Compile Data Set for Download or QSAR

Found 43 hits with Last Name = 'foo' and Initial = 'sy'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Membrane metallo-endopeptidase-like 1 (Homo sapiens (Human))	BDBM153119 (BDBM153120 | US8993631, 29) Show SMILES C[C@H](C[C@@H](Cc1ccc(cc1)-c1cccc(Cl)c1)NC(=O)c1cc(O)no1)C(O)=O Show InChI InChI=1S/C22H21ClN2O5/c1-13(22(28)29)9-18(24-21(27)19-12-20(26)25-30-19)10-14-5-7-15(8-6-14)16-3-2-4-17(23)11-16/h2-8,11-13,18H,9-10H2,1H3,(H,24,27)(H,25,26)(H,28,29)/t13-,18+/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.0300	n/a	n/a	n/a	n/a	7.4	25
Novartis AG US Patent					Assay Description Recombinant human neutral endopeptidase (expressed in insect cells and purified using standard methods, final concentration 7 μM) is pre-incubat...				US Patent US8993631 (2015) BindingDB Entry DOI: 10.7270/Q20C4THK
					More data for this Ligand-Target Pair
Membrane metallo-endopeptidase-like 1 (Homo sapiens (Human))	BDBM153119 (BDBM153120 | US8993631, 29) Show SMILES C[C@H](C[C@@H](Cc1ccc(cc1)-c1cccc(Cl)c1)NC(=O)c1cc(O)no1)C(O)=O Show InChI InChI=1S/C22H21ClN2O5/c1-13(22(28)29)9-18(24-21(27)19-12-20(26)25-30-19)10-14-5-7-15(8-6-14)16-3-2-4-17(23)11-16/h2-8,11-13,18H,9-10H2,1H3,(H,24,27)(H,25,26)(H,28,29)/t13-,18+/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.0400	n/a	n/a	n/a	n/a	7.4	25
Novartis AG US Patent					Assay Description Recombinant human neutral endopeptidase (expressed in insect cells and purified using standard methods, final concentration 7 μM) is pre-incubat...				US Patent US8993631 (2015) BindingDB Entry DOI: 10.7270/Q20C4THK
					More data for this Ligand-Target Pair
Membrane metallo-endopeptidase-like 1 (Homo sapiens (Human))	BDBM153105 (US8993631, 9-5) Show SMILES OC(=O)C[C@@H](Cc1ccc(cc1)-c1cccc(Cl)c1)NC(=O)C(\O)=C\C(O)=N |r| Show InChI InChI=1S/C20H19ClN2O5/c21-15-3-1-2-14(9-15)13-6-4-12(5-7-13)8-16(10-19(26)27)23-20(28)17(24)11-18(22)25/h1-7,9,11,16,24H,8,10H2,(H2,22,25)(H,23,28)(H,26,27)/b17-11-/t16-/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0700	n/a	n/a	n/a	n/a	7.4	25
Novartis AG US Patent					Assay Description Recombinant human neutral endopeptidase (expressed in insect cells and purified using standard methods, final concentration 7 μM) is pre-incubat...				US Patent US8993631 (2015) BindingDB Entry DOI: 10.7270/Q20C4THK
					More data for this Ligand-Target Pair
Membrane metallo-endopeptidase-like 1 (Homo sapiens (Human))	BDBM153122 (US8993631, 32-1) Show SMILES C[C@H](N[C@@H](Cc1ccc(cc1)-c1cccc(Cl)c1)C(=O)Nc1nnn[nH]1)C(O)=O Show InChI InChI=1S/C19H19ClN6O3/c1-11(18(28)29)21-16(17(27)22-19-23-25-26-24-19)9-12-5-7-13(8-6-12)14-3-2-4-15(20)10-14/h2-8,10-11,16,21H,9H2,1H3,(H,28,29)(H2,22,23,24,25,26,27)/t11-,16-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.0900	n/a	n/a	n/a	n/a	7.4	25
Novartis AG US Patent					Assay Description Recombinant human neutral endopeptidase (expressed in insect cells and purified using standard methods, final concentration 7 μM) is pre-incubat...				US Patent US8993631 (2015) BindingDB Entry DOI: 10.7270/Q20C4THK
					More data for this Ligand-Target Pair
Membrane metallo-endopeptidase-like 1 (Homo sapiens (Human))	BDBM153111 (US8993631, 10-1) Show SMILES OC(=O)CCC(=O)N[C@@H](CC(O)=O)Cc1ccc(cc1)-c1cc(Cl)ccc1Cl Show InChI InChI=1S/C20H19Cl2NO5/c21-14-5-6-17(22)16(10-14)13-3-1-12(2-4-13)9-15(11-20(27)28)23-18(24)7-8-19(25)26/h1-6,10,15H,7-9,11H2,(H,23,24)(H,25,26)(H,27,28)/t15-/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	7.4	25
Novartis AG US Patent					Assay Description Recombinant human neutral endopeptidase (expressed in insect cells and purified using standard methods, final concentration 7 μM) is pre-incubat...				US Patent US8993631 (2015) BindingDB Entry DOI: 10.7270/Q20C4THK
					More data for this Ligand-Target Pair
Membrane metallo-endopeptidase-like 1 (Homo sapiens (Human))	BDBM153127 (US8993631, 32-7) Show SMILES CC[C@H](N[C@@H](Cc1ccc(cc1)-c1cccc(Cl)c1)C(=O)Nc1nnn[nH]1)C(O)=O Show InChI InChI=1S/C20H21ClN6O3/c1-2-16(19(29)30)22-17(18(28)23-20-24-26-27-25-20)10-12-6-8-13(9-7-12)14-4-3-5-15(21)11-14/h3-9,11,16-17,22H,2,10H2,1H3,(H,29,30)(H2,23,24,25,26,27,28)/t16-,17-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	7.4	25
Novartis AG US Patent					Assay Description Recombinant human neutral endopeptidase (expressed in insect cells and purified using standard methods, final concentration 7 μM) is pre-incubat...				US Patent US8993631 (2015) BindingDB Entry DOI: 10.7270/Q20C4THK
					More data for this Ligand-Target Pair
Membrane metallo-endopeptidase-like 1 (Homo sapiens (Human))	BDBM153126 (US8993631, 32-6) Show SMILES OC(=O)[C@H](CCc1ccccc1)N[C@@H](Cc1ccc(cc1)-c1cccc(Cl)c1)C(=O)Nc1nnn[nH]1 Show InChI InChI=1S/C26H25ClN6O3/c27-21-8-4-7-20(16-21)19-12-9-18(10-13-19)15-23(24(34)29-26-30-32-33-31-26)28-22(25(35)36)14-11-17-5-2-1-3-6-17/h1-10,12-13,16,22-23,28H,11,14-15H2,(H,35,36)(H2,29,30,31,32,33,34)/t22-,23-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	7.4	25
Novartis AG US Patent					Assay Description Recombinant human neutral endopeptidase (expressed in insect cells and purified using standard methods, final concentration 7 μM) is pre-incubat...				US Patent US8993631 (2015) BindingDB Entry DOI: 10.7270/Q20C4THK
					More data for this Ligand-Target Pair
Membrane metallo-endopeptidase-like 1 (Homo sapiens (Human))	BDBM153121 (US8993631, 29-2 | US9006249, Example 49-1) Show SMILES C[C@@H](C[C@@H](Cc1ccc(cc1)-c1cccc(Cl)c1)NC(=O)c1cc(O)no1)C(O)=O Show InChI InChI=1S/C22H21ClN2O5/c1-13(22(28)29)9-18(24-21(27)19-12-20(26)25-30-19)10-14-5-7-15(8-6-14)16-3-2-4-17(23)11-16/h2-8,11-13,18H,9-10H2,1H3,(H,24,27)(H,25,26)(H,28,29)/t13-,18-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	7.4	25
Novartis AG US Patent					Assay Description Recombinant human neutral endopeptidase (expressed in insect cells and purified using standard methods, final concentration 7 μM) is pre-incubat...				US Patent US8993631 (2015) BindingDB Entry DOI: 10.7270/Q20C4THK
					More data for this Ligand-Target Pair
Membrane metallo-endopeptidase-like 1 (Homo sapiens (Human))	BDBM153123 (US8993631, 32-2) Show SMILES C[C@H](N[C@@H](Cc1ccc(cc1)-c1cc(Cl)ccc1Cl)C(=O)Nc1nnn[nH]1)C(O)=O Show InChI InChI=1S/C19H18Cl2N6O3/c1-10(18(29)30)22-16(17(28)23-19-24-26-27-25-19)8-11-2-4-12(5-3-11)14-9-13(20)6-7-15(14)21/h2-7,9-10,16,22H,8H2,1H3,(H,29,30)(H2,23,24,25,26,27,28)/t10-,16-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	7.4	25
Novartis AG US Patent					Assay Description Recombinant human neutral endopeptidase (expressed in insect cells and purified using standard methods, final concentration 7 μM) is pre-incubat...				US Patent US8993631 (2015) BindingDB Entry DOI: 10.7270/Q20C4THK
					More data for this Ligand-Target Pair
Membrane metallo-endopeptidase-like 1 (Homo sapiens (Human))	BDBM153128 (US8993631, 36) Show SMILES C[C@H](C[C@@H](Cc1ccc(cc1)-c1cccc(Cl)c1)NC(=O)CCC(O)=O)C(O)=O Show InChI InChI=1S/C22H24ClNO5/c1-14(22(28)29)11-19(24-20(25)9-10-21(26)27)12-15-5-7-16(8-6-15)17-3-2-4-18(23)13-17/h2-8,13-14,19H,9-12H2,1H3,(H,24,25)(H,26,27)(H,28,29)/t14-,19+/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	7.4	25
Novartis AG US Patent					Assay Description Recombinant human neutral endopeptidase (expressed in insect cells and purified using standard methods, final concentration 7 μM) is pre-incubat...				US Patent US8993631 (2015) BindingDB Entry DOI: 10.7270/Q20C4THK
					More data for this Ligand-Target Pair
Membrane metallo-endopeptidase-like 1 (Homo sapiens (Human))	BDBM153106 (US8993631, 9-7) Show SMILES CCc1ncc(o1)C(=O)N[C@@H](CC(O)=O)Cc1ccc(cc1)-c1cc(Cl)ccc1F |r| Show InChI InChI=1S/C22H20ClFN2O4/c1-2-20-25-12-19(30-20)22(29)26-16(11-21(27)28)9-13-3-5-14(6-4-13)17-10-15(23)7-8-18(17)24/h3-8,10,12,16H,2,9,11H2,1H3,(H,26,29)(H,27,28)/t16-/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	7.4	25
Novartis AG US Patent					Assay Description Recombinant human neutral endopeptidase (expressed in insect cells and purified using standard methods, final concentration 7 μM) is pre-incubat...				US Patent US8993631 (2015) BindingDB Entry DOI: 10.7270/Q20C4THK
					More data for this Ligand-Target Pair
Membrane metallo-endopeptidase-like 1 (Homo sapiens (Human))	BDBM130360 (US8822534, Example 5-46 | US8993631, 5-9) Show SMILES OC(=O)C[C@@H](Cc1ccc(cc1)-c1cccc(Cl)c1)NC(=O)c1n[nH]c(=O)o1 Show InChI InChI=1S/C19H16ClN3O5/c20-14-3-1-2-13(9-14)12-6-4-11(5-7-12)8-15(10-16(24)25)21-17(26)18-22-23-19(27)28-18/h1-7,9,15H,8,10H2,(H,21,26)(H,23,27)(H,24,25)/t15-/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	7.4	25
Novartis AG US Patent					Assay Description Recombinant human neutral endopeptidase (expressed in insect cells and purified using standard methods, final concentration 7 μM) is pre-incubat...				US Patent US8993631 (2015) BindingDB Entry DOI: 10.7270/Q20C4THK
					More data for this Ligand-Target Pair
Membrane metallo-endopeptidase-like 1 (Homo sapiens (Human))	BDBM130366 (US8822534, Example 11-11 | US8993631, 9-6) Show SMILES OC(=O)C[C@@H](Cc1ccc(cc1)-c1cccc(Cl)c1)NC(=O)C(F)(F)C(F)(F)C(O)=O Show InChI InChI=1S/C20H16ClF4NO5/c21-14-3-1-2-13(9-14)12-6-4-11(5-7-12)8-15(10-16(27)28)26-17(29)19(22,23)20(24,25)18(30)31/h1-7,9,15H,8,10H2,(H,26,29)(H,27,28)(H,30,31)/t15-/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	7.4	25
Novartis AG US Patent					Assay Description Recombinant human neutral endopeptidase (expressed in insect cells and purified using standard methods, final concentration 7 μM) is pre-incubat...				US Patent US8993631 (2015) BindingDB Entry DOI: 10.7270/Q20C4THK
					More data for this Ligand-Target Pair
Membrane metallo-endopeptidase-like 1 (Homo sapiens (Human))	BDBM130362 (US8822534, Example 5-55 | US8993631, 5-11) Show SMILES COc1ccc(F)cc1-c1ccc(C[C@H](CC(O)=O)NC(=O)c2cc(O)no2)cc1 Show InChI InChI=1S/C21H19FN2O6/c1-29-17-7-6-14(22)9-16(17)13-4-2-12(3-5-13)8-15(10-20(26)27)23-21(28)18-11-19(25)24-30-18/h2-7,9,11,15H,8,10H2,1H3,(H,23,28)(H,24,25)(H,26,27)/t15-/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.700	n/a	n/a	n/a	n/a	7.4	25
Novartis AG US Patent					Assay Description Recombinant human neutral endopeptidase (expressed in insect cells and purified using standard methods, final concentration 7 μM) is pre-incubat...				US Patent US8993631 (2015) BindingDB Entry DOI: 10.7270/Q20C4THK
					More data for this Ligand-Target Pair
Membrane metallo-endopeptidase-like 1 (Homo sapiens (Human))	BDBM130359 (US8822534, Example 5-39 | US8993631, 5-8) Show SMILES COc1ccc(Cl)cc1-c1ccc(C[C@H](CC(O)=O)NC(=O)CCC(O)=O)cc1 Show InChI InChI=1S/C21H22ClNO6/c1-29-18-7-6-15(22)11-17(18)14-4-2-13(3-5-14)10-16(12-21(27)28)23-19(24)8-9-20(25)26/h2-7,11,16H,8-10,12H2,1H3,(H,23,24)(H,25,26)(H,27,28)/t16-/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.700	n/a	n/a	n/a	n/a	7.4	25
Novartis AG US Patent					Assay Description Recombinant human neutral endopeptidase (expressed in insect cells and purified using standard methods, final concentration 7 μM) is pre-incubat...				US Patent US8993631 (2015) BindingDB Entry DOI: 10.7270/Q20C4THK
					More data for this Ligand-Target Pair
Membrane metallo-endopeptidase-like 1 (Homo sapiens (Human))	BDBM130369 (US8822534, Example 14-1 | US8993631, 11-1) Show SMILES OC(=O)CNC(=O)N[C@@H](CC(O)=O)Cc1ccc(cc1)-c1cccc(Cl)c1 Show InChI InChI=1S/C19H19ClN2O5/c20-15-3-1-2-14(9-15)13-6-4-12(5-7-13)8-16(10-17(23)24)22-19(27)21-11-18(25)26/h1-7,9,16H,8,10-11H2,(H,23,24)(H,25,26)(H2,21,22,27)/t16-/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.800	n/a	n/a	n/a	n/a	7.4	25
Novartis AG US Patent					Assay Description Recombinant human neutral endopeptidase (expressed in insect cells and purified using standard methods, final concentration 7 μM) is pre-incubat...				US Patent US8993631 (2015) BindingDB Entry DOI: 10.7270/Q20C4THK
					More data for this Ligand-Target Pair
Membrane metallo-endopeptidase-like 1 (Homo sapiens (Human))	BDBM153108 (US8993631, 16-5 | US9006249, Example 3-32 | US9603...) Show SMILES C[C@H](C[C@@H](Cc1ccc(cc1)-c1ccccc1)NC(=O)c1cc(ncn1)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C24H23N3O5/c1-15(23(29)30)11-19(27-22(28)20-13-21(24(31)32)26-14-25-20)12-16-7-9-18(10-8-16)17-5-3-2-4-6-17/h2-10,13-15,19H,11-12H2,1H3,(H,27,28)(H,29,30)(H,31,32)/t15-,19+/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	7.4	25
Novartis AG US Patent					Assay Description Recombinant human neutral endopeptidase (expressed in insect cells and purified using standard methods, final concentration 7 μM) is pre-incubat...				US Patent US8993631 (2015) BindingDB Entry DOI: 10.7270/Q20C4THK
					More data for this Ligand-Target Pair
Membrane metallo-endopeptidase-like 1 (Homo sapiens (Human))	BDBM130365 (US8822534, Example 11-1 | US8822534, Example 12-1 ...) Show SMILES OC(=O)CCC(=O)N[C@@H](CC(O)=O)Cc1ccc(cc1)-c1cccc(Cl)c1 Show InChI InChI=1S/C20H20ClNO5/c21-16-3-1-2-15(11-16)14-6-4-13(5-7-14)10-17(12-20(26)27)22-18(23)8-9-19(24)25/h1-7,11,17H,8-10,12H2,(H,22,23)(H,24,25)(H,26,27)/t17-/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid PDB UniChem Similars	US Patent	n/a	n/a	1.10	n/a	n/a	n/a	n/a	7.4	25
Novartis AG US Patent					Assay Description Recombinant human neutral endopeptidase (expressed in insect cells and purified using standard methods, final concentration 7 μM) is pre-incubat...				US Patent US8993631 (2015) BindingDB Entry DOI: 10.7270/Q20C4THK
					More data for this Ligand-Target Pair
Membrane metallo-endopeptidase-like 1 (Homo sapiens (Human))	BDBM130370 (US8822534, Example 15-1 | US8993631, 12-1) Show SMILES OC(=O)C[C@@H](Cc1ccc(cc1)-c1cccc(Cl)c1)NC(=O)c1nn[nH]n1 Show InChI InChI=1S/C18H16ClN5O3/c19-14-3-1-2-13(9-14)12-6-4-11(5-7-12)8-15(10-16(25)26)20-18(27)17-21-23-24-22-17/h1-7,9,15H,8,10H2,(H,20,27)(H,25,26)(H,21,22,23,24)/t15-/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.20	n/a	n/a	n/a	n/a	7.4	25
Novartis AG US Patent					Assay Description Recombinant human neutral endopeptidase (expressed in insect cells and purified using standard methods, final concentration 7 μM) is pre-incubat...				US Patent US8993631 (2015) BindingDB Entry DOI: 10.7270/Q20C4THK
					More data for this Ligand-Target Pair
Membrane metallo-endopeptidase-like 1 (Homo sapiens (Human))	BDBM130358 (US8822534, Example 5-37 | US8993631, 5-7) Show SMILES COc1ccc(F)cc1-c1ccc(C[C@H](CC(O)=O)NC(=O)CCC(O)=O)cc1 Show InChI InChI=1S/C21H22FNO6/c1-29-18-7-6-15(22)11-17(18)14-4-2-13(3-5-14)10-16(12-21(27)28)23-19(24)8-9-20(25)26/h2-7,11,16H,8-10,12H2,1H3,(H,23,24)(H,25,26)(H,27,28)/t16-/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.30	n/a	n/a	n/a	n/a	7.4	25
Novartis AG US Patent					Assay Description Recombinant human neutral endopeptidase (expressed in insect cells and purified using standard methods, final concentration 7 μM) is pre-incubat...				US Patent US8993631 (2015) BindingDB Entry DOI: 10.7270/Q20C4THK
					More data for this Ligand-Target Pair
Membrane metallo-endopeptidase-like 1 (Homo sapiens (Human))	BDBM138393 (US8877786, Example 3-7 | US8993631, 32-4) Show SMILES C[C@H](N[C@@H](Cc1ccc(cc1)-c1cccc(Cl)c1)C(=O)Nc1cc(O)no1)C(O)=O |r| Show InChI InChI=1S/C21H20ClN3O5/c1-12(21(28)29)23-17(20(27)24-19-11-18(26)25-30-19)9-13-5-7-14(8-6-13)15-3-2-4-16(22)10-15/h2-8,10-12,17,23H,9H2,1H3,(H,24,27)(H,25,26)(H,28,29)/t12-,17-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.40	n/a	n/a	n/a	n/a	7.4	25
Novartis AG US Patent					Assay Description Recombinant human neutral endopeptidase (expressed in insect cells and purified using standard methods, final concentration 7 μM) is pre-incubat...				US Patent US8993631 (2015) BindingDB Entry DOI: 10.7270/Q20C4THK
					More data for this Ligand-Target Pair
Membrane metallo-endopeptidase-like 1 (Homo sapiens (Human))	BDBM130361 (US8822534, Example 5-47 | US8993631, 5-10) Show SMILES CCc1ncc(o1)C(=O)N[C@@H](CC(O)=O)Cc1ccc(cc1)-c1cccc(Cl)c1 Show InChI InChI=1S/C22H21ClN2O4/c1-2-20-24-13-19(29-20)22(28)25-18(12-21(26)27)10-14-6-8-15(9-7-14)16-4-3-5-17(23)11-16/h3-9,11,13,18H,2,10,12H2,1H3,(H,25,28)(H,26,27)/t18-/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.70	n/a	n/a	n/a	n/a	7.4	25
Novartis AG US Patent					Assay Description Recombinant human neutral endopeptidase (expressed in insect cells and purified using standard methods, final concentration 7 μM) is pre-incubat...				US Patent US8993631 (2015) BindingDB Entry DOI: 10.7270/Q20C4THK
					More data for this Ligand-Target Pair
Membrane metallo-endopeptidase-like 1 (Homo sapiens (Human))	BDBM130356 (US8822534, Example 5-11 | US8993631, 5-4) Show SMILES OC(=O)C[C@@H](Cc1ccc(cc1)-c1ccccc1)NC(=O)c1cnc(O)nc1 Show InChI InChI=1S/C21H19N3O4/c25-19(26)11-18(24-20(27)17-12-22-21(28)23-13-17)10-14-6-8-16(9-7-14)15-4-2-1-3-5-15/h1-9,12-13,18H,10-11H2,(H,24,27)(H,25,26)(H,22,23,28)/t18-/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	7.4	25
Novartis AG US Patent					Assay Description Recombinant human neutral endopeptidase (expressed in insect cells and purified using standard methods, final concentration 7 μM) is pre-incubat...				US Patent US8993631 (2015) BindingDB Entry DOI: 10.7270/Q20C4THK
					More data for this Ligand-Target Pair
Membrane metallo-endopeptidase-like 1 (Homo sapiens (Human))	BDBM130355 (US8822534, Example 5-7 | US8993631, 5-3) Show SMILES COc1ccccc1-c1ccc(C[C@H](CC(O)=O)NC(=O)CCC(O)=O)cc1 Show InChI InChI=1S/C21H23NO6/c1-28-18-5-3-2-4-17(18)15-8-6-14(7-9-15)12-16(13-21(26)27)22-19(23)10-11-20(24)25/h2-9,16H,10-13H2,1H3,(H,22,23)(H,24,25)(H,26,27)/t16-/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	7.4	25
Novartis AG US Patent					Assay Description Recombinant human neutral endopeptidase (expressed in insect cells and purified using standard methods, final concentration 7 μM) is pre-incubat...				US Patent US8993631 (2015) BindingDB Entry DOI: 10.7270/Q20C4THK
					More data for this Ligand-Target Pair
Membrane metallo-endopeptidase-like 1 (Homo sapiens (Human))	BDBM130354 (US8822534, Example 5-4 | US8993631, 5-2) Show SMILES OC(=O)CCC(=O)N[C@@H](CC(O)=O)Cc1ccc(cc1)-c1cccc(F)c1 Show InChI InChI=1S/C20H20FNO5/c21-16-3-1-2-15(11-16)14-6-4-13(5-7-14)10-17(12-20(26)27)22-18(23)8-9-19(24)25/h1-7,11,17H,8-10,12H2,(H,22,23)(H,24,25)(H,26,27)/t17-/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	7.4	25
Novartis AG US Patent					Assay Description Recombinant human neutral endopeptidase (expressed in insect cells and purified using standard methods, final concentration 7 μM) is pre-incubat...				US Patent US8993631 (2015) BindingDB Entry DOI: 10.7270/Q20C4THK
					More data for this Ligand-Target Pair
Membrane metallo-endopeptidase-like 1 (Homo sapiens (Human))	BDBM153109 (US8993631, 16-8 | US9006249, Example 3-60) Show SMILES C[C@H](C[C@@H](Cc1ccc(cc1)-c1ccccc1)NC(=O)c1c[nH]c(n1)C(O)=O)C(O)=O |r| Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7.30	n/a	n/a	n/a	n/a	7.4	25
Novartis AG US Patent					Assay Description Recombinant human neutral endopeptidase (expressed in insect cells and purified using standard methods, final concentration 7 μM) is pre-incubat...				US Patent US8993631 (2015) BindingDB Entry DOI: 10.7270/Q20C4THK
					More data for this Ligand-Target Pair
Membrane metallo-endopeptidase-like 1 (Homo sapiens (Human))	BDBM153124 (US8993631, 32-3) Show SMILES C[C@H](N[C@@H](Cc1ccc(cc1)-c1ccccc1)C(=O)Nc1nnn[nH]1)C(O)=O Show InChI InChI=1S/C19H20N6O3/c1-12(18(27)28)20-16(17(26)21-19-22-24-25-23-19)11-13-7-9-15(10-8-13)14-5-3-2-4-6-14/h2-10,12,16,20H,11H2,1H3,(H,27,28)(H2,21,22,23,24,25,26)/t12-,16-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	7.4	25
Novartis AG US Patent					Assay Description Recombinant human neutral endopeptidase (expressed in insect cells and purified using standard methods, final concentration 7 μM) is pre-incubat...				US Patent US8993631 (2015) BindingDB Entry DOI: 10.7270/Q20C4THK
					More data for this Ligand-Target Pair
Membrane metallo-endopeptidase-like 1 (Homo sapiens (Human))	BDBM153118 (US8993631, 23) Show SMILES C[C@H](C[C@@H](Cc1ccc(cc1)-c1ccccc1)NC(=O)c1nnn[nH]1)C(O)=O Show InChI InChI=1S/C20H21N5O3/c1-13(20(27)28)11-17(21-19(26)18-22-24-25-23-18)12-14-7-9-16(10-8-14)15-5-3-2-4-6-15/h2-10,13,17H,11-12H2,1H3,(H,21,26)(H,27,28)(H,22,23,24,25)/t13-,17+/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	7.4	25
Novartis AG US Patent					Assay Description Recombinant human neutral endopeptidase (expressed in insect cells and purified using standard methods, final concentration 7 μM) is pre-incubat...				US Patent US8993631 (2015) BindingDB Entry DOI: 10.7270/Q20C4THK
					More data for this Ligand-Target Pair
Membrane metallo-endopeptidase-like 1 (Homo sapiens (Human))	BDBM130350 (US8822534, Example 3-25 | US8993631, 3-12) Show SMILES CCCCOC(=O)CCC(=O)N[C@@H](CC(O)=O)Cc1ccc(cc1)-c1cccc(Cl)c1 Show InChI InChI=1S/C24H28ClNO5/c1-2-3-13-31-24(30)12-11-22(27)26-21(16-23(28)29)14-17-7-9-18(10-8-17)19-5-4-6-20(25)15-19/h4-10,15,21H,2-3,11-14,16H2,1H3,(H,26,27)(H,28,29)/t21-/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	7.4	25
Novartis AG US Patent					Assay Description Recombinant human neutral endopeptidase (expressed in insect cells and purified using standard methods, final concentration 7 μM) is pre-incubat...				US Patent US8993631 (2015) BindingDB Entry DOI: 10.7270/Q20C4THK
					More data for this Ligand-Target Pair
Membrane metallo-endopeptidase-like 1 (Homo sapiens (Human))	BDBM130351 (US8822534, Example 3-26 | US8993631, 3-13) Show SMILES CCOC(=O)CCCC(=O)N[C@@H](CC(O)=O)Cc1ccc(cc1)-c1cccc(Cl)c1 Show InChI InChI=1S/C23H26ClNO5/c1-2-30-23(29)8-4-7-21(26)25-20(15-22(27)28)13-16-9-11-17(12-10-16)18-5-3-6-19(24)14-18/h3,5-6,9-12,14,20H,2,4,7-8,13,15H2,1H3,(H,25,26)(H,27,28)/t20-/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	7.4	25
Novartis AG US Patent					Assay Description Recombinant human neutral endopeptidase (expressed in insect cells and purified using standard methods, final concentration 7 μM) is pre-incubat...				US Patent US8993631 (2015) BindingDB Entry DOI: 10.7270/Q20C4THK
					More data for this Ligand-Target Pair
Membrane metallo-endopeptidase-like 1 (Homo sapiens (Human))	BDBM153110 (US8993631, 3-11) Show SMILES CCOC(=O)C[C@@H](Cc1ccc(cc1)-c1ccccc1)NC(=O)CN1CCCC1C(=O)OCc1ccccc1 Show InChI InChI=1S/C32H36N2O5/c1-2-38-31(36)21-28(20-24-15-17-27(18-16-24)26-12-7-4-8-13-26)33-30(35)22-34-19-9-14-29(34)32(37)39-23-25-10-5-3-6-11-25/h3-8,10-13,15-18,28-29H,2,9,14,19-23H2,1H3,(H,33,35)/t28-,29?/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	18	n/a	n/a	n/a	n/a	7.4	25
Novartis AG US Patent					Assay Description Recombinant human neutral endopeptidase (expressed in insect cells and purified using standard methods, final concentration 7 μM) is pre-incubat...				US Patent US8993631 (2015) BindingDB Entry DOI: 10.7270/Q20C4THK
					More data for this Ligand-Target Pair
Membrane metallo-endopeptidase-like 1 (Homo sapiens (Human))	BDBM7494 (US8822534, 5-36 | US8822534, Example 5-1 | US89936...) Show SMILES OC(=O)CCC(=O)N[C@@H](CC(O)=O)Cc1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C20H21NO5/c22-18(10-11-19(23)24)21-17(13-20(25)26)12-14-6-8-16(9-7-14)15-4-2-1-3-5-15/h1-9,17H,10-13H2,(H,21,22)(H,23,24)(H,25,26)/t17-/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	38	n/a	n/a	n/a	n/a	7.4	25
Novartis AG US Patent					Assay Description Recombinant human neutral endopeptidase (expressed in insect cells and purified using standard methods, final concentration 7 μM) is pre-incubat...				US Patent US8993631 (2015) BindingDB Entry DOI: 10.7270/Q20C4THK
					More data for this Ligand-Target Pair
Membrane metallo-endopeptidase-like 1 (Homo sapiens (Human))	BDBM130364 (US8822534, Example 9-1 | US8993631, 8-1) Show SMILES OC(=O)C[C@@H](Cc1ccc(cc1)-c1ccccc1)NC(=O)c1nnn[nH]1 Show InChI InChI=1S/C18H17N5O3/c24-16(25)11-15(19-18(26)17-20-22-23-21-17)10-12-6-8-14(9-7-12)13-4-2-1-3-5-13/h1-9,15H,10-11H2,(H,19,26)(H,24,25)(H,20,21,22,23)/t15-/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	56	n/a	n/a	n/a	n/a	7.4	25
Novartis AG US Patent					Assay Description Recombinant human neutral endopeptidase (expressed in insect cells and purified using standard methods, final concentration 7 μM) is pre-incubat...				US Patent US8993631 (2015) BindingDB Entry DOI: 10.7270/Q20C4THK
					More data for this Ligand-Target Pair
Membrane metallo-endopeptidase-like 1 (Homo sapiens (Human))	BDBM130357 (US8822534, Example 5-12 | US8993631, 5-5) Show SMILES OC(=O)C[C@@H](Cc1ccc(cc1)-c1ccccc1)NC(=O)c1cc(ncn1)C(O)=O Show InChI InChI=1S/C22H19N3O5/c26-20(27)11-17(25-21(28)18-12-19(22(29)30)24-13-23-18)10-14-6-8-16(9-7-14)15-4-2-1-3-5-15/h1-9,12-13,17H,10-11H2,(H,25,28)(H,26,27)(H,29,30)/t17-/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	67	n/a	n/a	n/a	n/a	7.4	25
Novartis AG US Patent					Assay Description Recombinant human neutral endopeptidase (expressed in insect cells and purified using standard methods, final concentration 7 μM) is pre-incubat...				US Patent US8993631 (2015) BindingDB Entry DOI: 10.7270/Q20C4THK
					More data for this Ligand-Target Pair
Membrane metallo-endopeptidase-like 1 (Homo sapiens (Human))	BDBM130363 (US8822534, Example 6-1 | US8993631, 6-1) Show SMILES OC(=O)CCNC(=O)[C@@H](CC(O)=O)Cc1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C20H21NO5/c22-18(23)10-11-21-20(26)17(13-19(24)25)12-14-6-8-16(9-7-14)15-4-2-1-3-5-15/h1-9,17H,10-13H2,(H,21,26)(H,22,23)(H,24,25)/t17-/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	75	n/a	n/a	n/a	n/a	7.4	25
Novartis AG US Patent					Assay Description Recombinant human neutral endopeptidase (expressed in insect cells and purified using standard methods, final concentration 7 μM) is pre-incubat...				US Patent US8993631 (2015) BindingDB Entry DOI: 10.7270/Q20C4THK
					More data for this Ligand-Target Pair
Membrane metallo-endopeptidase-like 1 (Homo sapiens (Human))	BDBM153125 (US8993631, 32-5) Show SMILES C[C@H](N[C@@H](Cc1ccc(cc1)-c1cccc(Cl)c1)C(=O)Nc1nnnn1C)C(O)=O Show InChI InChI=1S/C20H21ClN6O3/c1-12(19(29)30)22-17(18(28)23-20-24-25-26-27(20)2)10-13-6-8-14(9-7-13)15-4-3-5-16(21)11-15/h3-9,11-12,17,22H,10H2,1-2H3,(H,29,30)(H,23,24,26,28)/t12-,17-/m0/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	91	n/a	n/a	n/a	n/a	7.4	25
Novartis AG US Patent					Assay Description Recombinant human neutral endopeptidase (expressed in insect cells and purified using standard methods, final concentration 7 μM) is pre-incubat...				US Patent US8993631 (2015) BindingDB Entry DOI: 10.7270/Q20C4THK
					More data for this Ligand-Target Pair
Membrane metallo-endopeptidase-like 1 (Homo sapiens (Human))	BDBM153116 (US8993631, 19 | US9006249, Example 7-1 | US9603819...) Show SMILES C[C@H](C[C@@H](Cc1ccc(cc1)-c1ccccc1)NC(=O)NCC(O)=O)C(O)=O Show InChI InChI=1S/C21H24N2O5/c1-14(20(26)27)11-18(23-21(28)22-13-19(24)25)12-15-7-9-17(10-8-15)16-5-3-2-4-6-16/h2-10,14,18H,11-13H2,1H3,(H,24,25)(H,26,27)(H2,22,23,28)/t14-,18+/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	93	n/a	n/a	n/a	n/a	7.4	25
Novartis AG US Patent					Assay Description Recombinant human neutral endopeptidase (expressed in insect cells and purified using standard methods, final concentration 7 μM) is pre-incubat...				US Patent US8993631 (2015) BindingDB Entry DOI: 10.7270/Q20C4THK
					More data for this Ligand-Target Pair
Membrane metallo-endopeptidase-like 1 (Homo sapiens (Human))	BDBM153117 (US8993631, 20 | US9006249, Example 9-1 | US9603819...) Show SMILES C[C@H](C[C@@H](Cc1ccc(cc1)-c1ccccc1)NC(=O)n1ccc(n1)C(O)=O)C(O)=O Show InChI InChI=1S/C23H23N3O5/c1-15(21(27)28)13-19(24-23(31)26-12-11-20(25-26)22(29)30)14-16-7-9-18(10-8-16)17-5-3-2-4-6-17/h2-12,15,19H,13-14H2,1H3,(H,24,31)(H,27,28)(H,29,30)/t15-,19+/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	142	n/a	n/a	n/a	n/a	7.4	25
Novartis AG US Patent					Assay Description Recombinant human neutral endopeptidase (expressed in insect cells and purified using standard methods, final concentration 7 μM) is pre-incubat...				US Patent US8993631 (2015) BindingDB Entry DOI: 10.7270/Q20C4THK
					More data for this Ligand-Target Pair
Membrane metallo-endopeptidase-like 1 (Homo sapiens (Human))	BDBM153107 (US8993631, 16-3 | US9006249, Example 3-6 | US96038...) Show SMILES C[C@H](C[C@@H](Cc1ccc(cc1)-c1ccccc1)NC(=O)CCCc1ccc2nc(C)sc2c1)C(O)=O |r| Show InChI InChI=1S/C30H32N2O3S/c1-20(30(34)35)17-26(18-23-11-14-25(15-12-23)24-8-4-3-5-9-24)32-29(33)10-6-7-22-13-16-27-28(19-22)36-21(2)31-27/h3-5,8-9,11-16,19-20,26H,6-7,10,17-18H2,1-2H3,(H,32,33)(H,34,35)/t20-,26+/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	250	n/a	n/a	n/a	n/a	7.4	25
Novartis AG US Patent					Assay Description Recombinant human neutral endopeptidase (expressed in insect cells and purified using standard methods, final concentration 7 μM) is pre-incubat...				US Patent US8993631 (2015) BindingDB Entry DOI: 10.7270/Q20C4THK
					More data for this Ligand-Target Pair
Membrane metallo-endopeptidase-like 1 (Homo sapiens (Human))	BDBM153113 (US8993631, 15-1 | US9006249, Example 2-1 | US96038...) Show SMILES C[C@H](C[C@@H](Cc1ccc(cc1)-c1ccccc1)NC(=O)CC(C)(C)C(O)=O)C(O)=O Show InChI InChI=1S/C24H29NO5/c1-16(22(27)28)13-20(25-21(26)15-24(2,3)23(29)30)14-17-9-11-19(12-10-17)18-7-5-4-6-8-18/h4-12,16,20H,13-15H2,1-3H3,(H,25,26)(H,27,28)(H,29,30)/t16-,20+/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	267	n/a	n/a	n/a	n/a	7.4	25
Novartis AG US Patent					Assay Description Recombinant human neutral endopeptidase (expressed in insect cells and purified using standard methods, final concentration 7 μM) is pre-incubat...				US Patent US8993631 (2015) BindingDB Entry DOI: 10.7270/Q20C4THK
					More data for this Ligand-Target Pair
Membrane metallo-endopeptidase-like 1 (Homo sapiens (Human))	BDBM153112 (US8993631, 14-1 | US9006249, Example 1-1 | US96038...) Show SMILES C[C@H](C[C@@H](Cc1ccc(cc1)-c1ccccc1)NC(=O)c1cccc(c1)C(O)=O)C(O)=O Show InChI InChI=1S/C26H25NO5/c1-17(25(29)30)14-23(27-24(28)21-8-5-9-22(16-21)26(31)32)15-18-10-12-20(13-11-18)19-6-3-2-4-7-19/h2-13,16-17,23H,14-15H2,1H3,(H,27,28)(H,29,30)(H,31,32)/t17-,23+/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	283	n/a	n/a	n/a	n/a	7.4	25
Novartis AG US Patent					Assay Description Recombinant human neutral endopeptidase (expressed in insect cells and purified using standard methods, final concentration 7 μM) is pre-incubat...				US Patent US8993631 (2015) BindingDB Entry DOI: 10.7270/Q20C4THK
					More data for this Ligand-Target Pair
Membrane metallo-endopeptidase-like 1 (Homo sapiens (Human))	BDBM153114 (US8993631, 17 | US9006249, Example 5-1 | US9603819...) Show SMILES C[C@H](C[C@@H](Cc1ccc(cc1)-c1ccccc1)NC(=O)c1cc(=O)cc(o1)C(O)=O)C(O)=O Show InChI InChI=1S/C25H23NO7/c1-15(24(29)30)11-19(26-23(28)21-13-20(27)14-22(33-21)25(31)32)12-16-7-9-18(10-8-16)17-5-3-2-4-6-17/h2-10,13-15,19H,11-12H2,1H3,(H,26,28)(H,29,30)(H,31,32)/t15-,19+/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	350	n/a	n/a	n/a	n/a	7.4	25
Novartis AG US Patent					Assay Description Recombinant human neutral endopeptidase (expressed in insect cells and purified using standard methods, final concentration 7 μM) is pre-incubat...				US Patent US8993631 (2015) BindingDB Entry DOI: 10.7270/Q20C4THK
					More data for this Ligand-Target Pair
Membrane metallo-endopeptidase-like 1 (Homo sapiens (Human))	BDBM153115 (US8993631, 18-1 | US9006249, Example 6-1 | US96038...) Show SMILES C[C@H](C[C@@H](Cc1ccc(cc1)-c1ccccc1)NC(=O)N1CCC[C@H]1C(O)=O)C(O)=O Show InChI InChI=1S/C24H28N2O5/c1-16(22(27)28)14-20(25-24(31)26-13-5-8-21(26)23(29)30)15-17-9-11-19(12-10-17)18-6-3-2-4-7-18/h2-4,6-7,9-12,16,20-21H,5,8,13-15H2,1H3,(H,25,31)(H,27,28)(H,29,30)/t16-,20+,21+/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	450	n/a	n/a	n/a	n/a	7.4	25
Novartis AG US Patent					Assay Description Recombinant human neutral endopeptidase (expressed in insect cells and purified using standard methods, final concentration 7 μM) is pre-incubat...				US Patent US8993631 (2015) BindingDB Entry DOI: 10.7270/Q20C4THK
					More data for this Ligand-Target Pair