Compile Data Set for Download or QSAR

Found 24 hits with Last Name = 'gosetto' and Initial = 'f'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Quinolone resistance protein NorA (Staphylococcus aureus)	BDBM50434974 (CHEMBL2385690) Show SMILES CCCOc1ccc(cc1)-c1cc(OCCN2CCN(Cc3ccccc3)CC2)c2ccccc2n1 Show InChI InChI=1S/C31H35N3O2/c1-2-21-35-27-14-12-26(13-15-27)30-23-31(28-10-6-7-11-29(28)32-30)36-22-20-33-16-18-34(19-17-33)24-25-8-4-3-5-9-25/h3-15,23H,2,16-22,24H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Perugia Curated by ChEMBL					Assay Description Inhibition of NorA in Staphylococcus aureus 1199B harboring grlA A116E mutant assessed as inhibition of ethidium bromide efflux measured for 5 mins b...				J Med Chem 56: 4975-89 (2013) Article DOI: 10.1021/jm400262a BindingDB Entry DOI: 10.7270/Q2765GRD
					More data for this Ligand-Target Pair
Quinolone resistance protein NorA (Staphylococcus aureus)	BDBM50434973 (CHEMBL2385681) Show SMILES CCCOc1ccc(cc1)-c1cc(OCCCN(C)C)c2ccccc2n1 Show InChI InChI=1S/C23H28N2O2/c1-4-15-26-19-12-10-18(11-13-19)22-17-23(27-16-7-14-25(2)3)20-8-5-6-9-21(20)24-22/h5-6,8-13,17H,4,7,14-16H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Perugia Curated by ChEMBL					Assay Description Inhibition of NorA in Staphylococcus aureus 1199B harboring grlA A116E mutant assessed as inhibition of ethidium bromide efflux measured for 5 mins b...				J Med Chem 56: 4975-89 (2013) Article DOI: 10.1021/jm400262a BindingDB Entry DOI: 10.7270/Q2765GRD
					More data for this Ligand-Target Pair
Quinolone resistance protein NorA (Staphylococcus aureus)	BDBM50434972 (CHEMBL2385684) Show SMILES CCCOc1ccc(cc1)-c1cc(OCCN2CCCCCC2)c2ccccc2n1 Show InChI InChI=1S/C26H32N2O2/c1-2-18-29-22-13-11-21(12-14-22)25-20-26(23-9-5-6-10-24(23)27-25)30-19-17-28-15-7-3-4-8-16-28/h5-6,9-14,20H,2-4,7-8,15-19H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Perugia Curated by ChEMBL					Assay Description Inhibition of NorA in Staphylococcus aureus 1199B harboring grlA A116E mutant assessed as inhibition of ethidium bromide efflux measured for 5 mins b...				J Med Chem 56: 4975-89 (2013) Article DOI: 10.1021/jm400262a BindingDB Entry DOI: 10.7270/Q2765GRD
					More data for this Ligand-Target Pair
Quinolone resistance protein NorA (Staphylococcus aureus)	BDBM22416 ((3S,4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-f...) Show SMILES Fc1ccc(cc1)[C@@H]1CCNC[C@H]1COc1ccc2OCOc2c1 Show InChI InChI=1S/C19H20FNO3/c20-15-3-1-13(2-4-15)17-7-8-21-10-14(17)11-22-16-5-6-18-19(9-16)24-12-23-18/h1-6,9,14,17,21H,7-8,10-12H2/t14-,17-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universita` degli Studi di Perugia Curated by ChEMBL					Assay Description Inhibition of NorA in Staphylococcus aureus 1199B assessed as inhibition of ethidium bromide efflux dose response curve based fluorometric assay				J Med Chem 54: 5722-36 (2011) Article DOI: 10.1021/jm200370y BindingDB Entry DOI: 10.7270/Q2NS0V8C
					More data for this Ligand-Target Pair
Quinolone resistance protein NorA (Staphylococcus aureus)	BDBM50017712 ((-)-reserpine | (3beta,16beta,17alpha,18beta,20alp...) Show SMILES CO[C@H]1[C@@H](C[C@@H]2CN3CCc4c([nH]c5cc(OC)ccc45)[C@H]3C[C@@H]2[C@@H]1C(=O)OC)OC(=O)c1cc(OC)c(OC)c(OC)c1 |r| Show InChI InChI=1S/C33H40N2O9/c1-38-19-7-8-20-21-9-10-35-16-18-13-27(44-32(36)17-11-25(39-2)30(41-4)26(12-17)40-3)31(42-5)28(33(37)43-6)22(18)15-24(35)29(21)34-23(20)14-19/h7-8,11-12,14,18,22,24,27-28,31,34H,9-10,13,15-16H2,1-6H3/t18-,22+,24-,27-,28+,31+/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universita` degli Studi di Perugia Curated by ChEMBL					Assay Description Inhibition of NorA in Staphylococcus aureus 1199B assessed as inhibition of ethidium bromide efflux dose response curve based fluorometric assay				J Med Chem 54: 5722-36 (2011) Article DOI: 10.1021/jm200370y BindingDB Entry DOI: 10.7270/Q2NS0V8C
					More data for this Ligand-Target Pair
Quinolone resistance protein NorA (Staphylococcus aureus)	BDBM50350505 (CHEMBL1651180) Show SMILES CCCOc1ccc(cc1)-c1cc(OCCN(CC)CC)c2ccccc2n1 Show InChI InChI=1S/C24H30N2O2/c1-4-16-27-20-13-11-19(12-14-20)23-18-24(28-17-15-26(5-2)6-3)21-9-7-8-10-22(21)25-23/h7-14,18H,4-6,15-17H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universita` degli Studi di Perugia Curated by ChEMBL					Assay Description Inhibition of NorA in Staphylococcus aureus 1199B assessed as inhibition of ethidium bromide efflux dose response curve based fluorometric assay				J Med Chem 54: 5722-36 (2011) Article DOI: 10.1021/jm200370y BindingDB Entry DOI: 10.7270/Q2NS0V8C
					More data for this Ligand-Target Pair
Quinolone resistance protein NorA (Staphylococcus aureus)	BDBM50350506 (CHEMBL1651181) Show SMILES CCCOc1ccc(cc1)-c1cc(OCCN2CCCCC2)c2ccccc2n1 Show InChI InChI=1S/C25H30N2O2/c1-2-17-28-21-12-10-20(11-13-21)24-19-25(22-8-4-5-9-23(22)26-24)29-18-16-27-14-6-3-7-15-27/h4-5,8-13,19H,2-3,6-7,14-18H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universita` degli Studi di Perugia Curated by ChEMBL					Assay Description Inhibition of NorA in Staphylococcus aureus 1199B assessed as inhibition of ethidium bromide efflux dose response curve based fluorometric assay				J Med Chem 54: 5722-36 (2011) Article DOI: 10.1021/jm200370y BindingDB Entry DOI: 10.7270/Q2NS0V8C
					More data for this Ligand-Target Pair
Quinolone resistance protein NorA (Staphylococcus aureus)	BDBM50434971 (CHEMBL2385677) Show SMILES CCCOc1ccc(cc1)-c1cc(OCC(C)N(C)C)c2ccccc2n1 Show InChI InChI=1S/C23H28N2O2/c1-5-14-26-19-12-10-18(11-13-19)22-15-23(27-16-17(2)25(3)4)20-8-6-7-9-21(20)24-22/h6-13,15,17H,5,14,16H2,1-4H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Perugia Curated by ChEMBL					Assay Description Inhibition of NorA in Staphylococcus aureus 1199B harboring grlA A116E mutant assessed as inhibition of ethidium bromide efflux measured for 5 mins b...				J Med Chem 56: 4975-89 (2013) Article DOI: 10.1021/jm400262a BindingDB Entry DOI: 10.7270/Q2765GRD
					More data for this Ligand-Target Pair
Quinolone resistance protein NorA (Staphylococcus aureus)	BDBM50434970 (CHEMBL2385678) Show SMILES CCCOc1ccc(cc1)-c1cc(OC2CCCN(C)C2)c2ccccc2n1 Show InChI InChI=1S/C24H28N2O2/c1-3-15-27-19-12-10-18(11-13-19)23-16-24(21-8-4-5-9-22(21)25-23)28-20-7-6-14-26(2)17-20/h4-5,8-13,16,20H,3,6-7,14-15,17H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Perugia Curated by ChEMBL					Assay Description Inhibition of NorA in Staphylococcus aureus 1199B harboring grlA A116E mutant assessed as inhibition of ethidium bromide efflux measured for 5 mins b...				J Med Chem 56: 4975-89 (2013) Article DOI: 10.1021/jm400262a BindingDB Entry DOI: 10.7270/Q2765GRD
					More data for this Ligand-Target Pair
Quinolone resistance protein NorA (Staphylococcus aureus)	BDBM50434968 (CHEMBL2385688) Show SMILES CCCOc1ccc(cc1)-c1cc(OCCN2CCNCC2)c2ccccc2n1 Show InChI InChI=1S/C24H29N3O2/c1-2-16-28-20-9-7-19(8-10-20)23-18-24(21-5-3-4-6-22(21)26-23)29-17-15-27-13-11-25-12-14-27/h3-10,18,25H,2,11-17H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Perugia Curated by ChEMBL					Assay Description Inhibition of NorA in Staphylococcus aureus 1199B harboring grlA A116E mutant assessed as inhibition of ethidium bromide efflux measured for 5 mins b...				J Med Chem 56: 4975-89 (2013) Article DOI: 10.1021/jm400262a BindingDB Entry DOI: 10.7270/Q2765GRD
					More data for this Ligand-Target Pair
Quinolone resistance protein NorA (Staphylococcus aureus)	BDBM50434969 (CHEMBL2385680) Show SMILES CCCOc1ccc(cc1)-c1cc(OCCN(C(C)C)C(C)C)c2ccccc2n1 Show InChI InChI=1S/C26H34N2O2/c1-6-16-29-22-13-11-21(12-14-22)25-18-26(23-9-7-8-10-24(23)27-25)30-17-15-28(19(2)3)20(4)5/h7-14,18-20H,6,15-17H2,1-5H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Perugia Curated by ChEMBL					Assay Description Inhibition of NorA in Staphylococcus aureus 1199B harboring grlA A116E mutant assessed as inhibition of ethidium bromide efflux measured for 5 mins b...				J Med Chem 56: 4975-89 (2013) Article DOI: 10.1021/jm400262a BindingDB Entry DOI: 10.7270/Q2765GRD
					More data for this Ligand-Target Pair
Quinolone resistance protein NorA (Staphylococcus aureus)	BDBM50434967 (CHEMBL2385667) Show SMILES CCCOc1ccc(cc1)-c1cc(OCCN2CCC3(CC2)OCCO3)c2ccccc2n1 Show InChI InChI=1S/C27H32N2O4/c1-2-16-30-22-9-7-21(8-10-22)25-20-26(23-5-3-4-6-24(23)28-25)31-17-15-29-13-11-27(12-14-29)32-18-19-33-27/h3-10,20H,2,11-19H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Perugia Curated by ChEMBL					Assay Description Inhibition of NorA in Staphylococcus aureus 1199B harboring grlA A116E mutant assessed as inhibition of ethidium bromide efflux measured for 5 mins b...				J Med Chem 56: 4975-89 (2013) Article DOI: 10.1021/jm400262a BindingDB Entry DOI: 10.7270/Q2765GRD
					More data for this Ligand-Target Pair
Quinolone resistance protein NorA (Staphylococcus aureus)	BDBM50350505 (CHEMBL1651180) Show SMILES CCCOc1ccc(cc1)-c1cc(OCCN(CC)CC)c2ccccc2n1 Show InChI InChI=1S/C24H30N2O2/c1-4-16-27-20-13-11-19(12-14-20)23-18-24(28-17-15-26(5-2)6-3)21-9-7-8-10-22(21)25-23/h7-14,18H,4-6,15-17H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Perugia Curated by ChEMBL					Assay Description Inhibition of NorA in Staphylococcus aureus 1199B harboring grlA A116E mutant assessed as inhibition of ethidium bromide efflux measured for 5 mins b...				J Med Chem 56: 4975-89 (2013) Article DOI: 10.1021/jm400262a BindingDB Entry DOI: 10.7270/Q2765GRD
					More data for this Ligand-Target Pair
Quinolone resistance protein NorA (Staphylococcus aureus)	BDBM50017712 ((-)-reserpine | (3beta,16beta,17alpha,18beta,20alp...) Show SMILES CO[C@H]1[C@@H](C[C@@H]2CN3CCc4c([nH]c5cc(OC)ccc45)[C@H]3C[C@@H]2[C@@H]1C(=O)OC)OC(=O)c1cc(OC)c(OC)c(OC)c1 |r| Show InChI InChI=1S/C33H40N2O9/c1-38-19-7-8-20-21-9-10-35-16-18-13-27(44-32(36)17-11-25(39-2)30(41-4)26(12-17)40-3)31(42-5)28(33(37)43-6)22(18)15-24(35)29(21)34-23(20)14-19/h7-8,11-12,14,18,22,24,27-28,31,34H,9-10,13,15-16H2,1-6H3/t18-,22+,24-,27-,28+,31+/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	9.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Perugia Curated by ChEMBL					Assay Description Inhibition of NorA in Staphylococcus aureus 1199B harboring grlA A116E mutant assessed as inhibition of ethidium bromide efflux measured for 5 mins b...				J Med Chem 56: 4975-89 (2013) Article DOI: 10.1021/jm400262a BindingDB Entry DOI: 10.7270/Q2765GRD
					More data for this Ligand-Target Pair
Quinolone resistance protein NorA (Staphylococcus aureus)	BDBM50434966 (CHEMBL2385691) Show SMILES CCCCN(CCCC)CCOc1cc(nc2ccccc12)-c1ccc(OCCC)cc1 Show InChI InChI=1S/C28H38N2O2/c1-4-7-17-30(18-8-5-2)19-21-32-28-22-27(29-26-12-10-9-11-25(26)28)23-13-15-24(16-14-23)31-20-6-3/h9-16,22H,4-8,17-21H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Perugia Curated by ChEMBL					Assay Description Inhibition of NorA in Staphylococcus aureus 1199B harboring grlA A116E mutant assessed as inhibition of ethidium bromide efflux measured for 5 mins b...				J Med Chem 56: 4975-89 (2013) Article DOI: 10.1021/jm400262a BindingDB Entry DOI: 10.7270/Q2765GRD
					More data for this Ligand-Target Pair
Quinolone resistance protein NorA (Staphylococcus aureus)	BDBM50434964 (CHEMBL2385683) Show SMILES CCCOc1ccc(cc1)-c1cc(OCCN2CCCC2)c2ccccc2n1 Show InChI InChI=1S/C24H28N2O2/c1-2-16-27-20-11-9-19(10-12-20)23-18-24(21-7-3-4-8-22(21)25-23)28-17-15-26-13-5-6-14-26/h3-4,7-12,18H,2,5-6,13-17H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Perugia Curated by ChEMBL					Assay Description Inhibition of NorA in Staphylococcus aureus 1199B harboring grlA A116E mutant assessed as inhibition of ethidium bromide efflux measured for 5 mins b...				J Med Chem 56: 4975-89 (2013) Article DOI: 10.1021/jm400262a BindingDB Entry DOI: 10.7270/Q2765GRD
					More data for this Ligand-Target Pair
Quinolone resistance protein NorA (Staphylococcus aureus)	BDBM50434965 (CHEMBL2385675) Show SMILES CCCOc1ccc(cc1)-c1cc(OCCN)c2ccccc2n1 Show InChI InChI=1S/C20H22N2O2/c1-2-12-23-16-9-7-15(8-10-16)19-14-20(24-13-11-21)17-5-3-4-6-18(17)22-19/h3-10,14H,2,11-13,21H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Perugia Curated by ChEMBL					Assay Description Inhibition of NorA in Staphylococcus aureus 1199B harboring grlA A116E mutant assessed as inhibition of ethidium bromide efflux measured for 5 mins b...				J Med Chem 56: 4975-89 (2013) Article DOI: 10.1021/jm400262a BindingDB Entry DOI: 10.7270/Q2765GRD
					More data for this Ligand-Target Pair
Quinolone resistance protein NorA (Staphylococcus aureus)	BDBM50434963 (CHEMBL2385689) Show SMILES CCCOc1ccc(cc1)-c1cc(OCCN2CCN(C)CC2)c2ccccc2n1 Show InChI InChI=1S/C25H31N3O2/c1-3-17-29-21-10-8-20(9-11-21)24-19-25(22-6-4-5-7-23(22)26-24)30-18-16-28-14-12-27(2)13-15-28/h4-11,19H,3,12-18H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Perugia Curated by ChEMBL					Assay Description Inhibition of NorA in Staphylococcus aureus 1199B harboring grlA A116E mutant assessed as inhibition of ethidium bromide efflux measured for 5 mins b...				J Med Chem 56: 4975-89 (2013) Article DOI: 10.1021/jm400262a BindingDB Entry DOI: 10.7270/Q2765GRD
					More data for this Ligand-Target Pair
Quinolone resistance protein NorA (Staphylococcus aureus)	BDBM50434962 (CHEMBL2385670) Show SMILES CCCOc1ccc(cc1)-c1cc(OCCN(C)C)c2ccccc2n1 Show InChI InChI=1S/C22H26N2O2/c1-4-14-25-18-11-9-17(10-12-18)21-16-22(26-15-13-24(2)3)19-7-5-6-8-20(19)23-21/h5-12,16H,4,13-15H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Perugia Curated by ChEMBL					Assay Description Inhibition of NorA in Staphylococcus aureus 1199B harboring grlA A116E mutant assessed as inhibition of ethidium bromide efflux measured for 5 mins b...				J Med Chem 56: 4975-89 (2013) Article DOI: 10.1021/jm400262a BindingDB Entry DOI: 10.7270/Q2765GRD
					More data for this Ligand-Target Pair
Quinolone resistance protein NorA (Staphylococcus aureus)	BDBM50386656 (CHEMBL2048632) Show SMILES [O-][N+](=O)c1ccc(cc1)-n1nc(c2NS(=O)(=O)c3ccccc3-c12)-c1ccc(Cl)cc1 Show InChI InChI=1S/C21H13ClN4O4S/c22-14-7-5-13(6-8-14)19-20-21(17-3-1-2-4-18(17)31(29,30)24-20)25(23-19)15-9-11-16(12-10-15)26(27)28/h1-12,24H	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Perugia Curated by ChEMBL					Assay Description Inhibition of norA-mediated EtBr efflux in Staphylococcus aureus SA1199B overexpressing norA and expressing A116E GrlA mutation by fluorometry				J Med Chem 55: 3568-72 (2012) Article DOI: 10.1021/jm201446h BindingDB Entry DOI: 10.7270/Q2HD7WQ7
					More data for this Ligand-Target Pair
Quinolone resistance protein NorA (Staphylococcus aureus)	BDBM50434961 (CHEMBL2385682) Show SMILES CCCOc1ccc(cc1)-c1cc(OCCN2CCOCC2)c2ccccc2n1 Show InChI InChI=1S/C24H28N2O3/c1-2-14-28-20-9-7-19(8-10-20)23-18-24(21-5-3-4-6-22(21)25-23)29-17-13-26-11-15-27-16-12-26/h3-10,18H,2,11-17H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.07E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Perugia Curated by ChEMBL					Assay Description Inhibition of NorA in Staphylococcus aureus 1199B harboring grlA A116E mutant assessed as inhibition of ethidium bromide efflux measured for 5 mins b...				J Med Chem 56: 4975-89 (2013) Article DOI: 10.1021/jm400262a BindingDB Entry DOI: 10.7270/Q2765GRD
					More data for this Ligand-Target Pair
Quinolone resistance protein NorA (Staphylococcus aureus)	BDBM50434960 (CHEMBL2385676) Show SMILES CCCOc1ccc(cc1)-c1cc(OC(C)CN(C)C)c2ccccc2n1 Show InChI InChI=1S/C23H28N2O2/c1-5-14-26-19-12-10-18(11-13-19)22-15-23(27-17(2)16-25(3)4)20-8-6-7-9-21(20)24-22/h6-13,15,17H,5,14,16H2,1-4H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.33E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Perugia Curated by ChEMBL					Assay Description Inhibition of NorA in Staphylococcus aureus 1199B harboring grlA A116E mutant assessed as inhibition of ethidium bromide efflux measured for 5 mins b...				J Med Chem 56: 4975-89 (2013) Article DOI: 10.1021/jm400262a BindingDB Entry DOI: 10.7270/Q2765GRD
					More data for this Ligand-Target Pair
Quinolone resistance protein NorA (Staphylococcus aureus)	BDBM50434959 (CHEMBL2385679) Show SMILES CCCOc1ccc(cc1)-c1cc(OC2CN3CCC2CC3)c2ccccc2n1 |(30.56,-28.12,;30.56,-29.66,;31.9,-30.43,;31.9,-31.97,;30.56,-32.74,;29.23,-31.97,;27.9,-32.74,;27.9,-34.28,;29.23,-35.05,;30.56,-34.28,;26.56,-35.05,;26.56,-36.59,;25.23,-37.36,;25.23,-38.9,;26.56,-39.67,;26.56,-41.21,;27.9,-41.98,;27.22,-41,;28.5,-40.15,;27.9,-38.9,;29.23,-39.67,;29.23,-41.21,;23.9,-36.59,;22.56,-37.36,;21.23,-36.59,;21.23,-35.05,;22.56,-34.28,;23.9,-35.05,;25.23,-34.28,)| Show InChI InChI=1S/C25H28N2O2/c1-2-15-28-20-9-7-18(8-10-20)23-16-24(21-5-3-4-6-22(21)26-23)29-25-17-27-13-11-19(25)12-14-27/h3-10,16,19,25H,2,11-15,17H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.48E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Perugia Curated by ChEMBL					Assay Description Inhibition of NorA in Staphylococcus aureus 1199B harboring grlA A116E mutant assessed as inhibition of ethidium bromide efflux measured for 5 mins b...				J Med Chem 56: 4975-89 (2013) Article DOI: 10.1021/jm400262a BindingDB Entry DOI: 10.7270/Q2765GRD
					More data for this Ligand-Target Pair
Quinolone resistance protein NorA (Staphylococcus aureus)	BDBM11639 (4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...) Show SMILES Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F Show InChI InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Perugia Curated by ChEMBL					Assay Description Inhibition of norA-mediated EtBr efflux in Staphylococcus aureus SA1199B overexpressing norA and expressing A116E GrlA mutation by fluorometry				J Med Chem 55: 3568-72 (2012) Article DOI: 10.1021/jm201446h BindingDB Entry DOI: 10.7270/Q2HD7WQ7
					More data for this Ligand-Target Pair