Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM50417875 (CHEMBL1668063) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.0794 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Medicines Research Center Curated by ChEMBL | Assay Description Agonist activity at glucocorticoid receptor in human A549 cells by NF-kappaB transrepression assay | Bioorg Med Chem Lett 21: 1126-33 (2011) Article DOI: 10.1016/j.bmcl.2010.12.121 BindingDB Entry DOI: 10.7270/Q2571D8H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM50417887 (CHEMBL1668077) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.126 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Medicines Research Center Curated by ChEMBL | Assay Description Agonist activity at glucocorticoid receptor in human A549 cells by NF-kappaB transrepression assay | Bioorg Med Chem Lett 21: 1126-33 (2011) Article DOI: 10.1016/j.bmcl.2010.12.121 BindingDB Entry DOI: 10.7270/Q2571D8H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM50417890 (CHEMBL1668080) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Medicines Research Center Curated by ChEMBL | Assay Description Agonist activity at glucocorticoid receptor in human A549 cells by NF-kappaB transrepression assay | Bioorg Med Chem Lett 21: 1126-33 (2011) Article DOI: 10.1016/j.bmcl.2010.12.121 BindingDB Entry DOI: 10.7270/Q2571D8H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM50417889 (CHEMBL1668079) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.251 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Medicines Research Center Curated by ChEMBL | Assay Description Agonist activity at glucocorticoid receptor in human A549 cells by NF-kappaB transrepression assay | Bioorg Med Chem Lett 21: 1126-33 (2011) Article DOI: 10.1016/j.bmcl.2010.12.121 BindingDB Entry DOI: 10.7270/Q2571D8H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM50417875 (CHEMBL1668063) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.316 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Medicines Research Center Curated by ChEMBL | Assay Description Agonist activity at GR in human A549 cells transfected with luciferase gene linked to MMTV promoter assessed as luciferase transactivation activity | Bioorg Med Chem Lett 21: 1126-33 (2011) Article DOI: 10.1016/j.bmcl.2010.12.121 BindingDB Entry DOI: 10.7270/Q2571D8H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM50417888 (CHEMBL1668078) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.316 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Medicines Research Center Curated by ChEMBL | Assay Description Agonist activity at glucocorticoid receptor in human A549 cells by NF-kappaB transrepression assay | Bioorg Med Chem Lett 21: 1126-33 (2011) Article DOI: 10.1016/j.bmcl.2010.12.121 BindingDB Entry DOI: 10.7270/Q2571D8H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM50417891 (CHEMBL1668081) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.501 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Medicines Research Center Curated by ChEMBL | Assay Description Agonist activity at glucocorticoid receptor in human A549 cells by NF-kappaB transrepression assay | Bioorg Med Chem Lett 21: 1126-33 (2011) Article DOI: 10.1016/j.bmcl.2010.12.121 BindingDB Entry DOI: 10.7270/Q2571D8H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM50417887 (CHEMBL1668077) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.501 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Medicines Research Center Curated by ChEMBL | Assay Description Agonist activity at GR in human A549 cells transfected with luciferase gene linked to MMTV promoter assessed as luciferase transactivation activity | Bioorg Med Chem Lett 21: 1126-33 (2011) Article DOI: 10.1016/j.bmcl.2010.12.121 BindingDB Entry DOI: 10.7270/Q2571D8H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM18207 ((1R,2S,10S,11S,13R,14R,15S,17S)-1-fluoro-14,17-dih...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank PDB Article PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Medicines Research Center Curated by ChEMBL | Assay Description Agonist activity at glucocorticoid receptor in human A549 cells by NF-kappaB transrepression assay | Bioorg Med Chem Lett 21: 1126-33 (2011) Article DOI: 10.1016/j.bmcl.2010.12.121 BindingDB Entry DOI: 10.7270/Q2571D8H | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Bromodomain-containing protein 4 (Homo sapiens (Human)) | BDBM50576438 (CHEMBL4869149) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant human BRD4 BD2 (333 to 460 residues) expressed in bacterial expression system by bromoscan assay | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00344 BindingDB Entry DOI: 10.7270/Q2S46WSG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM50417888 (CHEMBL1668078) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.26 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Medicines Research Center Curated by ChEMBL | Assay Description Agonist activity at GR in human A549 cells transfected with luciferase gene linked to MMTV promoter assessed as luciferase transactivation activity | Bioorg Med Chem Lett 21: 1126-33 (2011) Article DOI: 10.1016/j.bmcl.2010.12.121 BindingDB Entry DOI: 10.7270/Q2571D8H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM50417876 (CHEMBL1668064) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.26 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Medicines Research Center Curated by ChEMBL | Assay Description Agonist activity at glucocorticoid receptor in human A549 cells by NF-kappaB transrepression assay | Bioorg Med Chem Lett 21: 1126-33 (2011) Article DOI: 10.1016/j.bmcl.2010.12.121 BindingDB Entry DOI: 10.7270/Q2571D8H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM50417883 (CHEMBL1668073) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.26 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Medicines Research Center Curated by ChEMBL | Assay Description Agonist activity at glucocorticoid receptor in human A549 cells by NF-kappaB transrepression assay | Bioorg Med Chem Lett 21: 1126-33 (2011) Article DOI: 10.1016/j.bmcl.2010.12.121 BindingDB Entry DOI: 10.7270/Q2571D8H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bromodomain-containing protein 3 (Homo sapiens (Human)) | BDBM50576438 (CHEMBL4869149) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant human BRD3 BD2 (306 to 416 residues) expressed in bacterial expression system by bromoscan assay | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00344 BindingDB Entry DOI: 10.7270/Q2S46WSG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM50417891 (CHEMBL1668081) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.58 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Medicines Research Center Curated by ChEMBL | Assay Description Agonist activity at GR in human A549 cells transfected with luciferase gene linked to MMTV promoter assessed as luciferase transactivation activity | Bioorg Med Chem Lett 21: 1126-33 (2011) Article DOI: 10.1016/j.bmcl.2010.12.121 BindingDB Entry DOI: 10.7270/Q2571D8H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bromodomain testis-specific protein (Homo sapiens (Human)) | BDBM50576438 (CHEMBL4869149) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant human BRDT BD2 (250 to 382 residues) expressed in bacterial expression system by bromoscan assay | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00344 BindingDB Entry DOI: 10.7270/Q2S46WSG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM50417896 (CHEMBL1668086) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Medicines Research Center Curated by ChEMBL | Assay Description Agonist activity at glucocorticoid receptor in human A549 cells by NF-kappaB transrepression assay | Bioorg Med Chem Lett 21: 1126-33 (2011) Article DOI: 10.1016/j.bmcl.2010.12.121 BindingDB Entry DOI: 10.7270/Q2571D8H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM50417890 (CHEMBL1668080) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Medicines Research Center Curated by ChEMBL | Assay Description Agonist activity at GR in human A549 cells transfected with luciferase gene linked to MMTV promoter assessed as luciferase transactivation activity | Bioorg Med Chem Lett 21: 1126-33 (2011) Article DOI: 10.1016/j.bmcl.2010.12.121 BindingDB Entry DOI: 10.7270/Q2571D8H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM50417882 (CHEMBL1668072) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Medicines Research Center Curated by ChEMBL | Assay Description Agonist activity at glucocorticoid receptor in human A549 cells by NF-kappaB transrepression assay | Bioorg Med Chem Lett 21: 1126-33 (2011) Article DOI: 10.1016/j.bmcl.2010.12.121 BindingDB Entry DOI: 10.7270/Q2571D8H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM50417879 (CHEMBL1668068) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Medicines Research Center Curated by ChEMBL | Assay Description Agonist activity at glucocorticoid receptor in human A549 cells by NF-kappaB transrepression assay | Bioorg Med Chem Lett 21: 1126-33 (2011) Article DOI: 10.1016/j.bmcl.2010.12.121 BindingDB Entry DOI: 10.7270/Q2571D8H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bromodomain-containing protein 2 (Homo sapiens (Human)) | BDBM50576438 (CHEMBL4869149) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant human BRD2 BD2 (348 to 455 residues) expressed in bacterial expression system by bromoscan assay | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00344 BindingDB Entry DOI: 10.7270/Q2S46WSG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM50417900 (CHEMBL1668090) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.51 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Medicines Research Center Curated by ChEMBL | Assay Description Agonist activity at glucocorticoid receptor in human A549 cells by NF-kappaB transrepression assay | Bioorg Med Chem Lett 21: 1126-33 (2011) Article DOI: 10.1016/j.bmcl.2010.12.121 BindingDB Entry DOI: 10.7270/Q2571D8H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM50417889 (CHEMBL1668079) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.51 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Medicines Research Center Curated by ChEMBL | Assay Description Agonist activity at GR in human A549 cells transfected with luciferase gene linked to MMTV promoter assessed as luciferase transactivation activity | Bioorg Med Chem Lett 21: 1126-33 (2011) Article DOI: 10.1016/j.bmcl.2010.12.121 BindingDB Entry DOI: 10.7270/Q2571D8H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM50417902 (CHEMBL1668089) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.16 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Medicines Research Center Curated by ChEMBL | Assay Description Agonist activity at glucocorticoid receptor in human A549 cells by NF-kappaB transrepression assay | Bioorg Med Chem Lett 21: 1126-33 (2011) Article DOI: 10.1016/j.bmcl.2010.12.121 BindingDB Entry DOI: 10.7270/Q2571D8H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM50417884 (CHEMBL1668074) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.16 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Medicines Research Center Curated by ChEMBL | Assay Description Agonist activity at glucocorticoid receptor in human A549 cells by NF-kappaB transrepression assay | Bioorg Med Chem Lett 21: 1126-33 (2011) Article DOI: 10.1016/j.bmcl.2010.12.121 BindingDB Entry DOI: 10.7270/Q2571D8H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM50417876 (CHEMBL1668064) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.98 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Medicines Research Center Curated by ChEMBL | Assay Description Agonist activity at GR in human A549 cells transfected with luciferase gene linked to MMTV promoter assessed as luciferase transactivation activity | Bioorg Med Chem Lett 21: 1126-33 (2011) Article DOI: 10.1016/j.bmcl.2010.12.121 BindingDB Entry DOI: 10.7270/Q2571D8H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM18207 ((1R,2S,10S,11S,13R,14R,15S,17S)-1-fluoro-14,17-dih...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank PDB Article PubMed | n/a | n/a | 3.98 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Medicines Research Center Curated by ChEMBL | Assay Description Agonist activity at GR in human A549 cells transfected with luciferase gene linked to MMTV promoter assessed as luciferase transactivation activity | Bioorg Med Chem Lett 21: 1126-33 (2011) Article DOI: 10.1016/j.bmcl.2010.12.121 BindingDB Entry DOI: 10.7270/Q2571D8H | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Bromodomain-containing protein 4 (Homo sapiens (Human)) | BDBM50576449 (CHEMBL4853098) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of 6His-Thr-BRD4 (1 to 477 residues) BD2 domain Y390A mutant (unknown origin) incubated for 30 mins by TR-FRET assay | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00344 BindingDB Entry DOI: 10.7270/Q2S46WSG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bromodomain-containing protein 4 (Homo sapiens (Human)) | BDBM50572841 (CHEMBL4854203) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of Alexa Fluor 647 labelled ligand from 6His-tagged BRD4 BD2/BD1 Y97A mutant (1 to 477 residue) (unknown origin) measured after 30 mins ... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00412 BindingDB Entry DOI: 10.7270/Q2W099RP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM50417880 (CHEMBL1668069) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.01 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Medicines Research Center Curated by ChEMBL | Assay Description Agonist activity at glucocorticoid receptor in human A549 cells by NF-kappaB transrepression assay | Bioorg Med Chem Lett 21: 1126-33 (2011) Article DOI: 10.1016/j.bmcl.2010.12.121 BindingDB Entry DOI: 10.7270/Q2571D8H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM50417881 (CHEMBL1668071) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.01 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Medicines Research Center Curated by ChEMBL | Assay Description Agonist activity at glucocorticoid receptor in human A549 cells by NF-kappaB transrepression assay | Bioorg Med Chem Lett 21: 1126-33 (2011) Article DOI: 10.1016/j.bmcl.2010.12.121 BindingDB Entry DOI: 10.7270/Q2571D8H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM50417897 (CHEMBL1668087) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.01 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Medicines Research Center Curated by ChEMBL | Assay Description Agonist activity at glucocorticoid receptor in human A549 cells by NF-kappaB transrepression assay | Bioorg Med Chem Lett 21: 1126-33 (2011) Article DOI: 10.1016/j.bmcl.2010.12.121 BindingDB Entry DOI: 10.7270/Q2571D8H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM50417879 (CHEMBL1668068) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.01 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Medicines Research Center Curated by ChEMBL | Assay Description Agonist activity at GR in human A549 cells transfected with luciferase gene linked to MMTV promoter assessed as luciferase transactivation activity | Bioorg Med Chem Lett 21: 1126-33 (2011) Article DOI: 10.1016/j.bmcl.2010.12.121 BindingDB Entry DOI: 10.7270/Q2571D8H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM50417898 (CHEMBL1668088) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.01 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Medicines Research Center Curated by ChEMBL | Assay Description Agonist activity at glucocorticoid receptor in human A549 cells by NF-kappaB transrepression assay | Bioorg Med Chem Lett 21: 1126-33 (2011) Article DOI: 10.1016/j.bmcl.2010.12.121 BindingDB Entry DOI: 10.7270/Q2571D8H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM50417891 (CHEMBL1668081) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.01 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Medicines Research Center Curated by ChEMBL | Assay Description Displacement of fluorescent-labelled Dexamethasone from glucocorticoid receptor | Bioorg Med Chem Lett 21: 1126-33 (2011) Article DOI: 10.1016/j.bmcl.2010.12.121 BindingDB Entry DOI: 10.7270/Q2571D8H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bromodomain-containing protein 4 (Homo sapiens (Human)) | BDBM50576462 (CHEMBL4874566) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 6.30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of 6His-Thr-BRD4 (1 to 477 residues) BD2 domain Y390A mutant (unknown origin) incubated for 30 mins by TR-FRET assay | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00344 BindingDB Entry DOI: 10.7270/Q2S46WSG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bromodomain-containing protein 3 (Homo sapiens (Human)) | BDBM50576438 (CHEMBL4869149) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 6.30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of 6His-Thr-BRD3 (1 to 435 residues) BD2 domain Y348A or Y73A mutant (unknown origin) incubated for 30 mins by TR-FRET assay | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00344 BindingDB Entry DOI: 10.7270/Q2S46WSG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM50417887 (CHEMBL1668077) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.31 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Medicines Research Center Curated by ChEMBL | Assay Description Displacement of fluorescent-labelled Dexamethasone from glucocorticoid receptor | Bioorg Med Chem Lett 21: 1126-33 (2011) Article DOI: 10.1016/j.bmcl.2010.12.121 BindingDB Entry DOI: 10.7270/Q2571D8H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM50417901 (CHEMBL1668065) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.31 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Medicines Research Center Curated by ChEMBL | Assay Description Agonist activity at glucocorticoid receptor in human A549 cells by NF-kappaB transrepression assay | Bioorg Med Chem Lett 21: 1126-33 (2011) Article DOI: 10.1016/j.bmcl.2010.12.121 BindingDB Entry DOI: 10.7270/Q2571D8H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bromodomain-containing protein 4 (Homo sapiens (Human)) | BDBM50572839 (CHEMBL4857388) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | 7.90 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of Alexa Fluor 647 labelled ligand from 6His-tagged BRD4 BD2/BD1 Y97A mutant (1 to 477 residue) (unknown origin) measured after 30 mins ... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00412 BindingDB Entry DOI: 10.7270/Q2W099RP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bromodomain testis-specific protein (Homo sapiens (Human)) | BDBM50576438 (CHEMBL4869149) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 7.90 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of 6His-FLAG-Tev-BRDT (1 to 397 residues) BD2 domain Y309A or Y66A mutant (unknown origin) incubated for 30 mins by TR-FRET assay | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00344 BindingDB Entry DOI: 10.7270/Q2S46WSG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bromodomain-containing protein 4 (Homo sapiens (Human)) | BDBM50576461 (CHEMBL4869239) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 7.90 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of 6His-Thr-BRD4 (1 to 477 residues) BD2 domain Y390A mutant (unknown origin) incubated for 30 mins by TR-FRET assay | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00344 BindingDB Entry DOI: 10.7270/Q2S46WSG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bromodomain-containing protein 4 (Homo sapiens (Human)) | BDBM50572865 (CHEMBL4869314) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 7.90 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of Alexa Fluor 647 labelled ligand from 6His-tagged BRD4 BD2/BD1 Y97A mutant (1 to 477 residue) (unknown origin) measured after 30 mins ... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00412 BindingDB Entry DOI: 10.7270/Q2W099RP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bromodomain-containing protein 4 (Homo sapiens (Human)) | BDBM50572846 (CHEMBL4878095) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 7.90 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of Alexa Fluor 647 labelled ligand from 6His-tagged BRD4 BD2/BD1 Y97A mutant (1 to 477 residue) (unknown origin) measured after 30 mins ... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00412 BindingDB Entry DOI: 10.7270/Q2W099RP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bromodomain-containing protein 4 (Homo sapiens (Human)) | BDBM50572840 (CHEMBL4863889) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 7.90 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of Alexa Fluor 647 labelled ligand from 6His-tagged BRD4 BD2/BD1 Y97A mutant (1 to 477 residue) (unknown origin) measured after 30 mins ... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00412 BindingDB Entry DOI: 10.7270/Q2W099RP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM50417883 (CHEMBL1668073) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.94 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Medicines Research Center Curated by ChEMBL | Assay Description Agonist activity at GR in human A549 cells transfected with luciferase gene linked to MMTV promoter assessed as luciferase transactivation activity | Bioorg Med Chem Lett 21: 1126-33 (2011) Article DOI: 10.1016/j.bmcl.2010.12.121 BindingDB Entry DOI: 10.7270/Q2571D8H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM50417885 (CHEMBL1668075) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.94 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Medicines Research Center Curated by ChEMBL | Assay Description Agonist activity at glucocorticoid receptor in human A549 cells by NF-kappaB transrepression assay | Bioorg Med Chem Lett 21: 1126-33 (2011) Article DOI: 10.1016/j.bmcl.2010.12.121 BindingDB Entry DOI: 10.7270/Q2571D8H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM50417895 (CHEMBL1668085) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.94 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Medicines Research Center Curated by ChEMBL | Assay Description Agonist activity at glucocorticoid receptor in human A549 cells by NF-kappaB transrepression assay | Bioorg Med Chem Lett 21: 1126-33 (2011) Article DOI: 10.1016/j.bmcl.2010.12.121 BindingDB Entry DOI: 10.7270/Q2571D8H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM50417897 (CHEMBL1668087) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.94 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Medicines Research Center Curated by ChEMBL | Assay Description Displacement of fluorescent-labelled Dexamethasone from glucocorticoid receptor | Bioorg Med Chem Lett 21: 1126-33 (2011) Article DOI: 10.1016/j.bmcl.2010.12.121 BindingDB Entry DOI: 10.7270/Q2571D8H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glucocorticoid receptor (Homo sapiens (Human)) | BDBM50417888 (CHEMBL1668078) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.94 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Medicines Research Center Curated by ChEMBL | Assay Description Displacement of fluorescent-labelled Dexamethasone from glucocorticoid receptor | Bioorg Med Chem Lett 21: 1126-33 (2011) Article DOI: 10.1016/j.bmcl.2010.12.121 BindingDB Entry DOI: 10.7270/Q2571D8H | |||||||||||
More data for this Ligand-Target Pair |
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