Found 44 hits with Last Name = 'henshaw' and Initial = 'e' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Integrin alpha-V
(Homo sapiens (Human)) | BDBM50296598
((R)-2-(2,4-dichlorophenylsulfonamido)-3-(thiophene...)Show SMILES OC(=O)[C@@H](CNC(=O)c1ccsc1)NS(=O)(=O)c1ccc(Cl)cc1Cl |r| Show InChI InChI=1S/C14H12Cl2N2O5S2/c15-9-1-2-12(10(16)5-9)25(22,23)18-11(14(20)21)6-17-13(19)8-3-4-24-7-8/h1-5,7,11,18H,6H2,(H,17,19)(H,20,21)/t11-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Inhibition of fibrinogen binding to alphavbeta3 integrin |
Bioorg Med Chem Lett 19: 4832-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.041
BindingDB Entry DOI: 10.7270/Q2CJ8DJQ |
More data for this
Ligand-Target Pair | |
Integrin alpha-V
(Homo sapiens (Human)) | BDBM50296610
((R)-3-(1-methyl-1H-pyrazole-5-carboxamido)-2-(2,4,...)Show SMILES Cc1cc(C)c(c(C)c1)S(=O)(=O)N[C@H](CNC(=O)c1ccnn1C)C(O)=O |r| Show InChI InChI=1S/C17H22N4O5S/c1-10-7-11(2)15(12(3)8-10)27(25,26)20-13(17(23)24)9-18-16(22)14-5-6-19-21(14)4/h5-8,13,20H,9H2,1-4H3,(H,18,22)(H,23,24)/t13-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Inhibition of fibrinogen binding to alphavbeta3 integrin |
Bioorg Med Chem Lett 19: 4832-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.041
BindingDB Entry DOI: 10.7270/Q2CJ8DJQ |
More data for this
Ligand-Target Pair | |
Integrin alpha-V
(Homo sapiens (Human)) | BDBM50296635
((R)-2-(2,3-dichlorophenylsulfonamido)-3-(thiophene...)Show SMILES OC(=O)[C@@H](CNC(=O)c1ccsc1)NS(=O)(=O)c1cccc(Cl)c1Cl |r| Show InChI InChI=1S/C14H12Cl2N2O5S2/c15-9-2-1-3-11(12(9)16)25(22,23)18-10(14(20)21)6-17-13(19)8-4-5-24-7-8/h1-5,7,10,18H,6H2,(H,17,19)(H,20,21)/t10-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Inhibition of fibrinogen binding to alphavbeta3 integrin |
Bioorg Med Chem Lett 19: 4832-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.041
BindingDB Entry DOI: 10.7270/Q2CJ8DJQ |
More data for this
Ligand-Target Pair | |
Integrin alpha-V
(Homo sapiens (Human)) | BDBM50296597
((R)-3-(thiophene-3-carboxamido)-2-(2,4,6-trichloro...)Show SMILES OC(=O)[C@@H](CNC(=O)c1ccsc1)NS(=O)(=O)c1c(Cl)cc(Cl)cc1Cl |r| Show InChI InChI=1S/C14H11Cl3N2O5S2/c15-8-3-9(16)12(10(17)4-8)26(23,24)19-11(14(21)22)5-18-13(20)7-1-2-25-6-7/h1-4,6,11,19H,5H2,(H,18,20)(H,21,22)/t11-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Inhibition of fibrinogen binding to alphavbeta3 integrin |
Bioorg Med Chem Lett 19: 4832-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.041
BindingDB Entry DOI: 10.7270/Q2CJ8DJQ |
More data for this
Ligand-Target Pair | |
Integrin alpha-V
(Homo sapiens (Human)) | BDBM50296603
((R)-3-benzamido-2-(2-iodophenylsulfonamido)propano...)Show SMILES OC(=O)[C@@H](CNC(=O)c1ccccc1)NS(=O)(=O)c1ccccc1I |r| Show InChI InChI=1S/C16H15IN2O5S/c17-12-8-4-5-9-14(12)25(23,24)19-13(16(21)22)10-18-15(20)11-6-2-1-3-7-11/h1-9,13,19H,10H2,(H,18,20)(H,21,22)/t13-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Inhibition of fibrinogen binding to alphavbeta3 integrin |
Bioorg Med Chem Lett 19: 4832-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.041
BindingDB Entry DOI: 10.7270/Q2CJ8DJQ |
More data for this
Ligand-Target Pair | |
Integrin alpha-V
(Homo sapiens (Human)) | BDBM50296611
((R)-3-(furan-3-carboxamido)-2-(2,4,6-trimethylphen...)Show SMILES Cc1cc(C)c(c(C)c1)S(=O)(=O)N[C@H](CNC(=O)c1ccoc1)C(O)=O |r| Show InChI InChI=1S/C17H20N2O6S/c1-10-6-11(2)15(12(3)7-10)26(23,24)19-14(17(21)22)8-18-16(20)13-4-5-25-9-13/h4-7,9,14,19H,8H2,1-3H3,(H,18,20)(H,21,22)/t14-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 32 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Inhibition of fibrinogen binding to alphavbeta3 integrin |
Bioorg Med Chem Lett 19: 4832-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.041
BindingDB Entry DOI: 10.7270/Q2CJ8DJQ |
More data for this
Ligand-Target Pair | |
Integrin alpha-V
(Homo sapiens (Human)) | BDBM50296609
((R)-3-(2-methyloxazole-4-carboxamido)-2-(2,4,6-tri...)Show SMILES Cc1nc(co1)C(=O)NC[C@@H](NS(=O)(=O)c1c(C)cc(C)cc1C)C(O)=O |r| Show InChI InChI=1S/C17H21N3O6S/c1-9-5-10(2)15(11(3)6-9)27(24,25)20-13(17(22)23)7-18-16(21)14-8-26-12(4)19-14/h5-6,8,13,20H,7H2,1-4H3,(H,18,21)(H,22,23)/t13-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 41 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Inhibition of fibrinogen binding to alphavbeta3 integrin |
Bioorg Med Chem Lett 19: 4832-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.041
BindingDB Entry DOI: 10.7270/Q2CJ8DJQ |
More data for this
Ligand-Target Pair | |
Integrin alpha-V
(Homo sapiens (Human)) | BDBM50296612
((R)-3-(thiophene-3-carboxamido)-2-(2,4,6-trimethyl...)Show SMILES Cc1cc(C)c(c(C)c1)S(=O)(=O)N[C@H](CNC(=O)c1ccsc1)C(O)=O |r| Show InChI InChI=1S/C17H20N2O5S2/c1-10-6-11(2)15(12(3)7-10)26(23,24)19-14(17(21)22)8-18-16(20)13-4-5-25-9-13/h4-7,9,14,19H,8H2,1-3H3,(H,18,20)(H,21,22)/t14-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 44 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Inhibition of fibrinogen binding to alphavbeta3 integrin |
Bioorg Med Chem Lett 19: 4832-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.041
BindingDB Entry DOI: 10.7270/Q2CJ8DJQ |
More data for this
Ligand-Target Pair | |
Integrin alpha-V
(Homo sapiens (Human)) | BDBM50296600
((R)-3-benzamido-2-(2,3-dichlorophenylsulfonamido)p...)Show SMILES OC(=O)[C@@H](CNC(=O)c1ccccc1)NS(=O)(=O)c1cccc(Cl)c1Cl |r| Show InChI InChI=1S/C16H14Cl2N2O5S/c17-11-7-4-8-13(14(11)18)26(24,25)20-12(16(22)23)9-19-15(21)10-5-2-1-3-6-10/h1-8,12,20H,9H2,(H,19,21)(H,22,23)/t12-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 62 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Inhibition of fibrinogen binding to alphavbeta3 integrin |
Bioorg Med Chem Lett 19: 4832-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.041
BindingDB Entry DOI: 10.7270/Q2CJ8DJQ |
More data for this
Ligand-Target Pair | |
Integrin alpha-V
(Homo sapiens (Human)) | BDBM50296607
((R)-3-(pyrimidine-5-carboxamido)-2-(2,4,6-trimethy...)Show SMILES Cc1cc(C)c(c(C)c1)S(=O)(=O)N[C@H](CNC(=O)c1cncnc1)C(O)=O |r| Show InChI InChI=1S/C17H20N4O5S/c1-10-4-11(2)15(12(3)5-10)27(25,26)21-14(17(23)24)8-20-16(22)13-6-18-9-19-7-13/h4-7,9,14,21H,8H2,1-3H3,(H,20,22)(H,23,24)/t14-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 63 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Inhibition of fibrinogen binding to alphavbeta3 integrin |
Bioorg Med Chem Lett 19: 4832-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.041
BindingDB Entry DOI: 10.7270/Q2CJ8DJQ |
More data for this
Ligand-Target Pair | |
Integrin alpha-V
(Homo sapiens (Human)) | BDBM50296632
((R)-3-(2-methoxybenzamido)-2-(2,4,6-trimethylpheny...)Show SMILES COc1ccccc1C(=O)NC[C@@H](NS(=O)(=O)c1c(C)cc(C)cc1C)C(O)=O |r| Show InChI InChI=1S/C20H24N2O6S/c1-12-9-13(2)18(14(3)10-12)29(26,27)22-16(20(24)25)11-21-19(23)15-7-5-6-8-17(15)28-4/h5-10,16,22H,11H2,1-4H3,(H,21,23)(H,24,25)/t16-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 78 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Inhibition of fibrinogen binding to alphavbeta3 integrin |
Bioorg Med Chem Lett 19: 4832-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.041
BindingDB Entry DOI: 10.7270/Q2CJ8DJQ |
More data for this
Ligand-Target Pair | |
Integrin alpha-V
(Homo sapiens (Human)) | BDBM50296608
((R)-3-(nicotinamido)-2-(2,4,6-trimethylphenylsulfo...)Show SMILES Cc1cc(C)c(c(C)c1)S(=O)(=O)N[C@H](CNC(=O)c1cccnc1)C(O)=O |r| Show InChI InChI=1S/C18H21N3O5S/c1-11-7-12(2)16(13(3)8-11)27(25,26)21-15(18(23)24)10-20-17(22)14-5-4-6-19-9-14/h4-9,15,21H,10H2,1-3H3,(H,20,22)(H,23,24)/t15-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 81 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Inhibition of fibrinogen binding to alphavbeta3 integrin |
Bioorg Med Chem Lett 19: 4832-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.041
BindingDB Entry DOI: 10.7270/Q2CJ8DJQ |
More data for this
Ligand-Target Pair | |
Integrin alpha-V
(Homo sapiens (Human)) | BDBM50296596
((R)-2-(3-cyanophenylsulfonamido)-3-(furan-3-carbox...)Show SMILES OC(=O)[C@@H](CNC(=O)c1ccoc1)NS(=O)(=O)c1cccc(c1)C#N |r| Show InChI InChI=1S/C15H13N3O6S/c16-7-10-2-1-3-12(6-10)25(22,23)18-13(15(20)21)8-17-14(19)11-4-5-24-9-11/h1-6,9,13,18H,8H2,(H,17,19)(H,20,21)/t13-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 98 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Inhibition of fibrinogen binding to alphavbeta3 integrin |
Bioorg Med Chem Lett 19: 4832-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.041
BindingDB Entry DOI: 10.7270/Q2CJ8DJQ |
More data for this
Ligand-Target Pair | |
Integrin alpha-V
(Homo sapiens (Human)) | BDBM50296599
((R)-3-benzamido-2-(2,6-dichlorophenylsulfonamido)p...)Show SMILES OC(=O)[C@@H](CNC(=O)c1ccccc1)NS(=O)(=O)c1c(Cl)cccc1Cl |r| Show InChI InChI=1S/C16H14Cl2N2O5S/c17-11-7-4-8-12(18)14(11)26(24,25)20-13(16(22)23)9-19-15(21)10-5-2-1-3-6-10/h1-8,13,20H,9H2,(H,19,21)(H,22,23)/t13-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 118 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Inhibition of fibrinogen binding to alphavbeta3 integrin |
Bioorg Med Chem Lett 19: 4832-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.041
BindingDB Entry DOI: 10.7270/Q2CJ8DJQ |
More data for this
Ligand-Target Pair | |
Integrin alpha-V
(Homo sapiens (Human)) | BDBM50296623
((R)-3-benzamido-2-(2,4,6-trimethylphenylsulfonamid...)Show SMILES Cc1cc(C)c(c(C)c1)S(=O)(=O)N[C@H](CNC(=O)c1ccccc1)C(O)=O |r| Show InChI InChI=1S/C19H22N2O5S/c1-12-9-13(2)17(14(3)10-12)27(25,26)21-16(19(23)24)11-20-18(22)15-7-5-4-6-8-15/h4-10,16,21H,11H2,1-3H3,(H,20,22)(H,23,24)/t16-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Inhibition of fibrinogen binding to alphavbeta3 integrin |
Bioorg Med Chem Lett 19: 4832-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.041
BindingDB Entry DOI: 10.7270/Q2CJ8DJQ |
More data for this
Ligand-Target Pair | |
Integrin alpha-V
(Homo sapiens (Human)) | BDBM50296595
((R)-3-(furan-3-carboxamido)-2-(3-methoxyphenylsulf...)Show SMILES COc1cccc(c1)S(=O)(=O)N[C@H](CNC(=O)c1ccoc1)C(O)=O |r| Show InChI InChI=1S/C15H16N2O7S/c1-23-11-3-2-4-12(7-11)25(21,22)17-13(15(19)20)8-16-14(18)10-5-6-24-9-10/h2-7,9,13,17H,8H2,1H3,(H,16,18)(H,19,20)/t13-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 208 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Inhibition of fibrinogen binding to alphavbeta3 integrin |
Bioorg Med Chem Lett 19: 4832-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.041
BindingDB Entry DOI: 10.7270/Q2CJ8DJQ |
More data for this
Ligand-Target Pair | |
Integrin alpha-V
(Homo sapiens (Human)) | BDBM50296633
((R)-3-(furan-3-carboxamido)-2-(2-methylphenylsulfo...)Show SMILES Cc1ccccc1S(=O)(=O)N[C@H](CNC(=O)c1ccoc1)C(O)=O |r| Show InChI InChI=1S/C15H16N2O6S/c1-10-4-2-3-5-13(10)24(21,22)17-12(15(19)20)8-16-14(18)11-6-7-23-9-11/h2-7,9,12,17H,8H2,1H3,(H,16,18)(H,19,20)/t12-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 260 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Inhibition of fibrinogen binding to alphavbeta3 integrin |
Bioorg Med Chem Lett 19: 4832-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.041
BindingDB Entry DOI: 10.7270/Q2CJ8DJQ |
More data for this
Ligand-Target Pair | |
Integrin alpha-V
(Homo sapiens (Human)) | BDBM50296604
((R)-3-benzamido-2-(2-chlorophenylsulfonamido)propa...)Show SMILES OC(=O)[C@@H](CNC(=O)c1ccccc1)NS(=O)(=O)c1ccccc1Cl |r| Show InChI InChI=1S/C16H15ClN2O5S/c17-12-8-4-5-9-14(12)25(23,24)19-13(16(21)22)10-18-15(20)11-6-2-1-3-7-11/h1-9,13,19H,10H2,(H,18,20)(H,21,22)/t13-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 260 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Inhibition of fibrinogen binding to alphavbeta3 integrin |
Bioorg Med Chem Lett 19: 4832-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.041
BindingDB Entry DOI: 10.7270/Q2CJ8DJQ |
More data for this
Ligand-Target Pair | |
Integrin alpha-V
(Homo sapiens (Human)) | BDBM50296606
((R)-3-(isonicotinamido)-2-(2,4,6-trimethylphenylsu...)Show SMILES Cc1cc(C)c(c(C)c1)S(=O)(=O)N[C@H](CNC(=O)c1ccncc1)C(O)=O |r| Show InChI InChI=1S/C18H21N3O5S/c1-11-8-12(2)16(13(3)9-11)27(25,26)21-15(18(23)24)10-20-17(22)14-4-6-19-7-5-14/h4-9,15,21H,10H2,1-3H3,(H,20,22)(H,23,24)/t15-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 301 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Inhibition of fibrinogen binding to alphavbeta3 integrin |
Bioorg Med Chem Lett 19: 4832-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.041
BindingDB Entry DOI: 10.7270/Q2CJ8DJQ |
More data for this
Ligand-Target Pair | |
Integrin alpha-V
(Homo sapiens (Human)) | BDBM50296605
((R)-3-benzamido-2-(2-methylphenylsulfonamido)propa...)Show SMILES Cc1ccccc1S(=O)(=O)N[C@H](CNC(=O)c1ccccc1)C(O)=O |r| Show InChI InChI=1S/C17H18N2O5S/c1-12-7-5-6-10-15(12)25(23,24)19-14(17(21)22)11-18-16(20)13-8-3-2-4-9-13/h2-10,14,19H,11H2,1H3,(H,18,20)(H,21,22)/t14-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 320 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Inhibition of fibrinogen binding to alphavbeta3 integrin |
Bioorg Med Chem Lett 19: 4832-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.041
BindingDB Entry DOI: 10.7270/Q2CJ8DJQ |
More data for this
Ligand-Target Pair | |
Integrin alpha-V
(Homo sapiens (Human)) | BDBM50296634
((R)-3-(furan-3-carboxamido)-2-(2-methoxyphenylsulf...)Show SMILES COc1ccccc1S(=O)(=O)N[C@H](CNC(=O)c1ccoc1)C(O)=O |r| Show InChI InChI=1S/C15H16N2O7S/c1-23-12-4-2-3-5-13(12)25(21,22)17-11(15(19)20)8-16-14(18)10-6-7-24-9-10/h2-7,9,11,17H,8H2,1H3,(H,16,18)(H,19,20)/t11-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 700 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Inhibition of fibrinogen binding to alphavbeta3 integrin |
Bioorg Med Chem Lett 19: 4832-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.041
BindingDB Entry DOI: 10.7270/Q2CJ8DJQ |
More data for this
Ligand-Target Pair | |
Integrin alpha-V
(Homo sapiens (Human)) | BDBM50296601
((R)-3-benzamido-2-(2-methoxyphenylsulfonamido)prop...)Show SMILES COc1ccccc1S(=O)(=O)N[C@H](CNC(=O)c1ccccc1)C(O)=O |r| Show InChI InChI=1S/C17H18N2O6S/c1-25-14-9-5-6-10-15(14)26(23,24)19-13(17(21)22)11-18-16(20)12-7-3-2-4-8-12/h2-10,13,19H,11H2,1H3,(H,18,20)(H,21,22)/t13-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 729 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Inhibition of fibrinogen binding to alphavbeta3 integrin |
Bioorg Med Chem Lett 19: 4832-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.041
BindingDB Entry DOI: 10.7270/Q2CJ8DJQ |
More data for this
Ligand-Target Pair | |
Integrin alpha-V
(Homo sapiens (Human)) | BDBM50296594
((R)-3-(furan-3-carboxamido)-2-(pyridine-3-sulfonam...)Show SMILES OC(=O)[C@@H](CNC(=O)c1ccoc1)NS(=O)(=O)c1cccnc1 |r| Show InChI InChI=1S/C13H13N3O6S/c17-12(9-3-5-22-8-9)15-7-11(13(18)19)16-23(20,21)10-2-1-4-14-6-10/h1-6,8,11,16H,7H2,(H,15,17)(H,18,19)/t11-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 793 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Inhibition of fibrinogen binding to alphavbeta3 integrin |
Bioorg Med Chem Lett 19: 4832-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.041
BindingDB Entry DOI: 10.7270/Q2CJ8DJQ |
More data for this
Ligand-Target Pair | |
Integrin alpha-V
(Homo sapiens (Human)) | BDBM50296629
((R)-3-acetamido-2-(2,4,6-trimethylphenylsulfonamid...)Show SMILES CC(=O)NC[C@@H](NS(=O)(=O)c1c(C)cc(C)cc1C)C(O)=O |r| Show InChI InChI=1S/C14H20N2O5S/c1-8-5-9(2)13(10(3)6-8)22(20,21)16-12(14(18)19)7-15-11(4)17/h5-6,12,16H,7H2,1-4H3,(H,15,17)(H,18,19)/t12-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Inhibition of fibrinogen binding to alphavbeta3 integrin |
Bioorg Med Chem Lett 19: 4832-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.041
BindingDB Entry DOI: 10.7270/Q2CJ8DJQ |
More data for this
Ligand-Target Pair | |
Integrin alpha-V
(Homo sapiens (Human)) | BDBM50296631
((R)-3-(1-oxoisoindolin-2-yl)-2-(2,4,6-trimethylphe...)Show SMILES Cc1cc(C)c(c(C)c1)S(=O)(=O)N[C@H](CN1Cc2ccccc2C1=O)C(O)=O |r| Show InChI InChI=1S/C20H22N2O5S/c1-12-8-13(2)18(14(3)9-12)28(26,27)21-17(20(24)25)11-22-10-15-6-4-5-7-16(15)19(22)23/h4-9,17,21H,10-11H2,1-3H3,(H,24,25)/t17-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 975 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Inhibition of fibrinogen binding to alphavbeta3 integrin |
Bioorg Med Chem Lett 19: 4832-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.041
BindingDB Entry DOI: 10.7270/Q2CJ8DJQ |
More data for this
Ligand-Target Pair | |
Integrin alpha-2
(Homo sapiens (Human)) | BDBM50296633
((R)-3-(furan-3-carboxamido)-2-(2-methylphenylsulfo...)Show SMILES Cc1ccccc1S(=O)(=O)N[C@H](CNC(=O)c1ccoc1)C(O)=O |r| Show InChI InChI=1S/C15H16N2O6S/c1-10-4-2-3-5-13(10)24(21,22)17-12(15(19)20)8-16-14(18)11-6-7-23-9-11/h2-7,9,12,17H,8H2,1H3,(H,16,18)(H,19,20)/t12-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.38E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Inhibition of fibrinogen binding to alpha2beta3a integrin |
Bioorg Med Chem Lett 19: 4832-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.041
BindingDB Entry DOI: 10.7270/Q2CJ8DJQ |
More data for this
Ligand-Target Pair | |
Integrin alpha-V
(Homo sapiens (Human)) | BDBM50296602
((R)-3-benzamido-2-(2-(methylsulfonyl)phenylsulfona...)Show SMILES CS(=O)(=O)c1ccccc1S(=O)(=O)N[C@H](CNC(=O)c1ccccc1)C(O)=O |r| Show InChI InChI=1S/C17H18N2O7S2/c1-27(23,24)14-9-5-6-10-15(14)28(25,26)19-13(17(21)22)11-18-16(20)12-7-3-2-4-8-12/h2-10,13,19H,11H2,1H3,(H,18,20)(H,21,22)/t13-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Inhibition of fibrinogen binding to alphavbeta3 integrin |
Bioorg Med Chem Lett 19: 4832-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.041
BindingDB Entry DOI: 10.7270/Q2CJ8DJQ |
More data for this
Ligand-Target Pair | |
Integrin alpha-V
(Homo sapiens (Human)) | BDBM50296630
((R)-3-(2-(furan-3-yl)-2-oxoethylamino)-2-(2,4,6-tr...)Show SMILES Cc1cc(C)c(c(C)c1)S(=O)(=O)N[C@H](CNCC(=O)c1ccoc1)C(O)=O |r| Show InChI InChI=1S/C18H22N2O6S/c1-11-6-12(2)17(13(3)7-11)27(24,25)20-15(18(22)23)8-19-9-16(21)14-4-5-26-10-14/h4-7,10,15,19-20H,8-9H2,1-3H3,(H,22,23)/t15-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 8.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Inhibition of fibrinogen binding to alphavbeta3 integrin |
Bioorg Med Chem Lett 19: 4832-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.041
BindingDB Entry DOI: 10.7270/Q2CJ8DJQ |
More data for this
Ligand-Target Pair | |
Integrin alpha-V
(Homo sapiens (Human)) | BDBM50296620
((S)-3-acetamido-2-(2,4,6-trimethylphenylsulfonamid...)Show SMILES CC(=O)NC[C@H](NS(=O)(=O)c1c(C)cc(C)cc1C)C(O)=O |r| Show InChI InChI=1S/C14H20N2O5S/c1-8-5-9(2)13(10(3)6-8)22(20,21)16-12(14(18)19)7-15-11(4)17/h5-6,12,16H,7H2,1-4H3,(H,15,17)(H,18,19)/t12-/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 8.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Inhibition of fibrinogen binding to alphavbeta3 integrin |
Bioorg Med Chem Lett 19: 4832-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.041
BindingDB Entry DOI: 10.7270/Q2CJ8DJQ |
More data for this
Ligand-Target Pair | |
Integrin alpha-V
(Homo sapiens (Human)) | BDBM50296619
((R)-3-acetamido-2-(phenylsulfonamido)propanoic aci...)Show SMILES CC(=O)NC[C@@H](NS(=O)(=O)c1ccccc1)C(O)=O |r| Show InChI InChI=1S/C11H14N2O5S/c1-8(14)12-7-10(11(15)16)13-19(17,18)9-5-3-2-4-6-9/h2-6,10,13H,7H2,1H3,(H,12,14)(H,15,16)/t10-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 9.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Inhibition of fibrinogen binding to alphavbeta3 integrin |
Bioorg Med Chem Lett 19: 4832-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.041
BindingDB Entry DOI: 10.7270/Q2CJ8DJQ |
More data for this
Ligand-Target Pair | |
Integrin alpha-V
(Homo sapiens (Human)) | BDBM50296627
((R)-3-butyramido-2-(2,4,6-trimethylphenylsulfonami...)Show SMILES CCCC(=O)NC[C@@H](NS(=O)(=O)c1c(C)cc(C)cc1C)C(O)=O |r| Show InChI InChI=1S/C16H24N2O5S/c1-5-6-14(19)17-9-13(16(20)21)18-24(22,23)15-11(3)7-10(2)8-12(15)4/h7-8,13,18H,5-6,9H2,1-4H3,(H,17,19)(H,20,21)/t13-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Inhibition of fibrinogen binding to alphavbeta3 integrin |
Bioorg Med Chem Lett 19: 4832-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.041
BindingDB Entry DOI: 10.7270/Q2CJ8DJQ |
More data for this
Ligand-Target Pair | |
Integrin alpha-V
(Homo sapiens (Human)) | BDBM50296628
((R)-3-amino-2-(2,4,6-trimethylphenylsulfonamido)pr...)Show SMILES Cc1cc(C)c(c(C)c1)S(=O)(=O)N[C@H](CN)C(O)=O |r| Show InChI InChI=1S/C12H18N2O4S/c1-7-4-8(2)11(9(3)5-7)19(17,18)14-10(6-13)12(15)16/h4-5,10,14H,6,13H2,1-3H3,(H,15,16)/t10-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Inhibition of fibrinogen binding to alphavbeta3 integrin |
Bioorg Med Chem Lett 19: 4832-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.041
BindingDB Entry DOI: 10.7270/Q2CJ8DJQ |
More data for this
Ligand-Target Pair | |
Integrin alpha-V
(Homo sapiens (Human)) | BDBM50296626
((R)-3-(tert-butoxycarbonylamino)-2-(2,4,6-trimethy...)Show SMILES Cc1cc(C)c(c(C)c1)S(=O)(=O)N[C@H](CNC(=O)OC(C)(C)C)C(O)=O |r| Show InChI InChI=1S/C17H26N2O6S/c1-10-7-11(2)14(12(3)8-10)26(23,24)19-13(15(20)21)9-18-16(22)25-17(4,5)6/h7-8,13,19H,9H2,1-6H3,(H,18,22)(H,20,21)/t13-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Inhibition of fibrinogen binding to alphavbeta3 integrin |
Bioorg Med Chem Lett 19: 4832-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.041
BindingDB Entry DOI: 10.7270/Q2CJ8DJQ |
More data for this
Ligand-Target Pair | |
Integrin alpha-V
(Homo sapiens (Human)) | BDBM50296625
((R)-3-(methoxycarbonylamino)-2-(2,4,6-trimethylphe...)Show SMILES COC(=O)NC[C@@H](NS(=O)(=O)c1c(C)cc(C)cc1C)C(O)=O |r| Show InChI InChI=1S/C14H20N2O6S/c1-8-5-9(2)12(10(3)6-8)23(20,21)16-11(13(17)18)7-15-14(19)22-4/h5-6,11,16H,7H2,1-4H3,(H,15,19)(H,17,18)/t11-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Inhibition of fibrinogen binding to alphavbeta3 integrin |
Bioorg Med Chem Lett 19: 4832-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.041
BindingDB Entry DOI: 10.7270/Q2CJ8DJQ |
More data for this
Ligand-Target Pair | |
Integrin alpha-V
(Homo sapiens (Human)) | BDBM50296624
((R)-3-(methylsulfonamido)-2-(2,4,6-trimethylphenyl...)Show SMILES Cc1cc(C)c(c(C)c1)S(=O)(=O)N[C@H](CNS(C)(=O)=O)C(O)=O |r| Show InChI InChI=1S/C13H20N2O6S2/c1-8-5-9(2)12(10(3)6-8)23(20,21)15-11(13(16)17)7-14-22(4,18)19/h5-6,11,14-15H,7H2,1-4H3,(H,16,17)/t11-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Inhibition of fibrinogen binding to alphavbeta3 integrin |
Bioorg Med Chem Lett 19: 4832-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.041
BindingDB Entry DOI: 10.7270/Q2CJ8DJQ |
More data for this
Ligand-Target Pair | |
Integrin alpha-V
(Homo sapiens (Human)) | BDBM50296622
((R)-3-(2-phenylacetamido)-2-(2,4,6-trimethylphenyl...)Show SMILES Cc1cc(C)c(c(C)c1)S(=O)(=O)N[C@H](CNC(=O)Cc1ccccc1)C(O)=O |r| Show InChI InChI=1S/C20H24N2O5S/c1-13-9-14(2)19(15(3)10-13)28(26,27)22-17(20(24)25)12-21-18(23)11-16-7-5-4-6-8-16/h4-10,17,22H,11-12H2,1-3H3,(H,21,23)(H,24,25)/t17-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Inhibition of fibrinogen binding to alphavbeta3 integrin |
Bioorg Med Chem Lett 19: 4832-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.041
BindingDB Entry DOI: 10.7270/Q2CJ8DJQ |
More data for this
Ligand-Target Pair | |
Integrin alpha-V
(Homo sapiens (Human)) | BDBM50296621
((R)-3-(benzylamino)-2-(2,4,6-trimethylphenylsulfon...)Show SMILES Cc1cc(C)c(c(C)c1)S(=O)(=O)N[C@H](CNCc1ccccc1)C(O)=O |r| Show InChI InChI=1S/C19H24N2O4S/c1-13-9-14(2)18(15(3)10-13)26(24,25)21-17(19(22)23)12-20-11-16-7-5-4-6-8-16/h4-10,17,20-21H,11-12H2,1-3H3,(H,22,23)/t17-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Inhibition of fibrinogen binding to alphavbeta3 integrin |
Bioorg Med Chem Lett 19: 4832-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.041
BindingDB Entry DOI: 10.7270/Q2CJ8DJQ |
More data for this
Ligand-Target Pair | |
Integrin alpha-V
(Homo sapiens (Human)) | BDBM50296618
((R)-3-acetamido-2-(phenylmethylsulfonamido)propano...)Show SMILES CC(=O)NC[C@@H](NS(=O)(=O)Cc1ccccc1)C(O)=O |r| Show InChI InChI=1S/C12H16N2O5S/c1-9(15)13-7-11(12(16)17)14-20(18,19)8-10-5-3-2-4-6-10/h2-6,11,14H,7-8H2,1H3,(H,13,15)(H,16,17)/t11-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Inhibition of fibrinogen binding to alphavbeta3 integrin |
Bioorg Med Chem Lett 19: 4832-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.041
BindingDB Entry DOI: 10.7270/Q2CJ8DJQ |
More data for this
Ligand-Target Pair | |
Integrin alpha-V
(Homo sapiens (Human)) | BDBM50296617
((R)-3-acetamido-2-benzamidopropanoic acid | CHEMBL...)Show InChI InChI=1S/C12H14N2O4/c1-8(15)13-7-10(12(17)18)14-11(16)9-5-3-2-4-6-9/h2-6,10H,7H2,1H3,(H,13,15)(H,14,16)(H,17,18)/t10-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Inhibition of fibrinogen binding to alphavbeta3 integrin |
Bioorg Med Chem Lett 19: 4832-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.041
BindingDB Entry DOI: 10.7270/Q2CJ8DJQ |
More data for this
Ligand-Target Pair | |
Integrin alpha-V
(Homo sapiens (Human)) | BDBM50296616
((R)-3-acetamido-2-(2,6-dichlorobenzamido)propanoic...)Show SMILES CC(=O)NC[C@@H](NC(=O)c1c(Cl)cccc1Cl)C(O)=O |r| Show InChI InChI=1S/C12H12Cl2N2O4/c1-6(17)15-5-9(12(19)20)16-11(18)10-7(13)3-2-4-8(10)14/h2-4,9H,5H2,1H3,(H,15,17)(H,16,18)(H,19,20)/t9-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Inhibition of fibrinogen binding to alphavbeta3 integrin |
Bioorg Med Chem Lett 19: 4832-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.041
BindingDB Entry DOI: 10.7270/Q2CJ8DJQ |
More data for this
Ligand-Target Pair | |
Integrin alpha-V
(Homo sapiens (Human)) | BDBM50296614
((R)-3-acetamido-2-(tert-butoxycarbonylamino)propan...)Show InChI InChI=1S/C10H18N2O5/c1-6(13)11-5-7(8(14)15)12-9(16)17-10(2,3)4/h7H,5H2,1-4H3,(H,11,13)(H,12,16)(H,14,15)/t7-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Inhibition of fibrinogen binding to alphavbeta3 integrin |
Bioorg Med Chem Lett 19: 4832-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.041
BindingDB Entry DOI: 10.7270/Q2CJ8DJQ |
More data for this
Ligand-Target Pair | |
Integrin alpha-V
(Homo sapiens (Human)) | BDBM50296613
((R)-3-acetamido-2-(N,2,4,6-tetramethylphenylsulfon...)Show SMILES CN([C@H](CNC(C)=O)C(O)=O)S(=O)(=O)c1c(C)cc(C)cc1C |r| Show InChI InChI=1S/C15H22N2O5S/c1-9-6-10(2)14(11(3)7-9)23(21,22)17(5)13(15(19)20)8-16-12(4)18/h6-7,13H,8H2,1-5H3,(H,16,18)(H,19,20)/t13-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Inhibition of fibrinogen binding to alphavbeta3 integrin |
Bioorg Med Chem Lett 19: 4832-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.041
BindingDB Entry DOI: 10.7270/Q2CJ8DJQ |
More data for this
Ligand-Target Pair | |
Integrin alpha-V
(Homo sapiens (Human)) | BDBM50296615
((R)-3-acetamido-2-(phenoxycarbonylamino)propanoic ...)Show InChI InChI=1S/C12H14N2O5/c1-8(15)13-7-10(11(16)17)14-12(18)19-9-5-3-2-4-6-9/h2-6,10H,7H2,1H3,(H,13,15)(H,14,18)(H,16,17)/t10-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Inhibition of fibrinogen binding to alphavbeta3 integrin |
Bioorg Med Chem Lett 19: 4832-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.041
BindingDB Entry DOI: 10.7270/Q2CJ8DJQ |
More data for this
Ligand-Target Pair | |
Integrin alpha-2
(Homo sapiens (Human)) | BDBM50296634
((R)-3-(furan-3-carboxamido)-2-(2-methoxyphenylsulf...)Show SMILES COc1ccccc1S(=O)(=O)N[C@H](CNC(=O)c1ccoc1)C(O)=O |r| Show InChI InChI=1S/C15H16N2O7S/c1-23-12-4-2-3-5-13(12)25(21,22)17-11(15(19)20)8-16-14(18)10-6-7-24-9-10/h2-7,9,11,17H,8H2,1H3,(H,16,18)(H,19,20)/t11-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Inhibition of fibrinogen binding to alpha2beta3a integrin |
Bioorg Med Chem Lett 19: 4832-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.041
BindingDB Entry DOI: 10.7270/Q2CJ8DJQ |
More data for this
Ligand-Target Pair | |
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