Found 134 hits with Last Name = 'higgins' and Initial = 'ma' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM22416
((3S,4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-f...)Show SMILES Fc1ccc(cc1)[C@@H]1CCNC[C@H]1COc1ccc2OCOc2c1 Show InChI InChI=1S/C19H20FNO3/c20-15-3-1-13(2-4-15)17-7-8-21-10-14(17)11-22-16-5-6-18-19(9-16)24-12-23-18/h1-6,9,14,17,21H,7-8,10-12H2/t14-,17-/m0/s1 | PDB
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| 0.0400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description Binding inhibition towards human serotonin transporter |
J Med Chem 48: 6023-34 (2005)
Article DOI: 10.1021/jm0503291 BindingDB Entry DOI: 10.7270/Q2PN96DN |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50173715
((+)3-((1S,2S)-2-Dimethylaminomethyl-cyclopropyl)-1...)Show InChI InChI=1S/C15H17N3/c1-18(2)9-11-6-12(11)14-8-17-15-4-3-10(7-16)5-13(14)15/h3-5,8,11-12,17H,6,9H2,1-2H3/t11-,12+/m1/s1 | PDB
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| 0.180 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description In vitro binding inhibition towards human serotonin transporter |
J Med Chem 48: 6023-34 (2005)
Article DOI: 10.1021/jm0503291 BindingDB Entry DOI: 10.7270/Q2PN96DN |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50173715
((+)3-((1S,2S)-2-Dimethylaminomethyl-cyclopropyl)-1...)Show InChI InChI=1S/C15H17N3/c1-18(2)9-11-6-12(11)14-8-17-15-4-3-10(7-16)5-13(14)15/h3-5,8,11-12,17H,6,9H2,1-2H3/t11-,12+/m1/s1 | PDB
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| 0.560 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description Binding inhibition towards human serotonin transporter |
J Med Chem 48: 6023-34 (2005)
Article DOI: 10.1021/jm0503291 BindingDB Entry DOI: 10.7270/Q2PN96DN |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50173710
(3-((1S,2S)-2-Dimethylaminomethyl-cyclopropyl)-1H-i...)Show InChI InChI=1S/C15H17N3/c1-18(2)9-11-6-13(11)14-8-17-15-10(7-16)4-3-5-12(14)15/h3-5,8,11,13,17H,6,9H2,1-2H3/t11-,13+/m1/s1 | PDB
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| 0.580 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description Binding inhibition towards human serotonin transporter |
J Med Chem 48: 6023-34 (2005)
Article DOI: 10.1021/jm0503291 BindingDB Entry DOI: 10.7270/Q2PN96DN |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM30130
(CHEMBL1201082 | CHEMBL41 | Fluoxetin | Fluoxetine ...)Show InChI InChI=1S/C17H18F3NO/c1-21-12-11-16(13-5-3-2-4-6-13)22-15-9-7-14(8-10-15)17(18,19)20/h2-10,16,21H,11-12H2,1H3 | PDB
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| 0.720 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description Binding inhibition towards human serotonin transporter |
J Med Chem 48: 6023-34 (2005)
Article DOI: 10.1021/jm0503291 BindingDB Entry DOI: 10.7270/Q2PN96DN |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 2
(Homo sapiens (Human)) | BDBM50209103
(CHEMBL3885379)Show SMILES FC(F)(F)c1c(OC[C@H]2C[C@@H]2c2ccc(Cl)cc2)ccn2c(CC3CC3)nnc12 |r| Show InChI InChI=1S/C21H19ClF3N3O/c22-15-5-3-13(4-6-15)16-10-14(16)11-29-17-7-8-28-18(9-12-1-2-12)26-27-20(28)19(17)21(23,24)25/h3-8,12,14,16H,1-2,9-11H2/t14-,16-/m1/s1 | PDB
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| 1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb
Curated by ChEMBL
| Assay Description Displacement of [3H]-JNJ-40068782 from human mGlu2 receptor expressed in HEK293 cell membranes coexpressing rat glutamate transporter measured after ... |
Bioorg Med Chem 25: 496-513 (2017)
Article DOI: 10.1016/j.bmc.2016.11.018 BindingDB Entry DOI: 10.7270/Q2QR504D |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50173712
(3-((1S,2S)-2-Dimethylaminomethyl-cyclopropyl)-1-et...)Show InChI InChI=1S/C17H21N3/c1-4-20-11-16(14-8-13(14)10-19(2)3)15-7-12(9-18)5-6-17(15)20/h5-7,11,13-14H,4,8,10H2,1-3H3/t13-,14+/m1/s1 | PDB
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| 1.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description Binding inhibition towards human serotonin transporter |
J Med Chem 48: 6023-34 (2005)
Article DOI: 10.1021/jm0503291 BindingDB Entry DOI: 10.7270/Q2PN96DN |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50162700
(3-(3-(dimethylamino)propyl)-1H-indole-5-carbonitri...)Show InChI InChI=1S/C14H17N3/c1-17(2)7-3-4-12-10-16-14-6-5-11(9-15)8-13(12)14/h5-6,8,10,16H,3-4,7H2,1-2H3 | PDB
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| 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description Binding inhibition towards human serotonin transporter |
J Med Chem 48: 6023-34 (2005)
Article DOI: 10.1021/jm0503291 BindingDB Entry DOI: 10.7270/Q2PN96DN |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50173717
(((1S,2S)-2-(5-fluoro-1H-indol-3-yl)cyclopropyl)-N,...)Show InChI InChI=1S/C14H17FN2/c1-17(2)8-9-5-11(9)13-7-16-14-4-3-10(15)6-12(13)14/h3-4,6-7,9,11,16H,5,8H2,1-2H3/t9-,11+/m1/s1 | PDB
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| 2.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description Binding inhibition towards human serotonin transporter |
J Med Chem 48: 6023-34 (2005)
Article DOI: 10.1021/jm0503291 BindingDB Entry DOI: 10.7270/Q2PN96DN |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50173717
(((1S,2S)-2-(5-fluoro-1H-indol-3-yl)cyclopropyl)-N,...)Show InChI InChI=1S/C14H17FN2/c1-17(2)8-9-5-11(9)13-7-16-14-4-3-10(15)6-12(13)14/h3-4,6-7,9,11,16H,5,8H2,1-2H3/t9-,11+/m1/s1 | PDB
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| Article PubMed
| 2.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description Binding inhibition towards human serotonin transporter |
J Med Chem 48: 6023-34 (2005)
Article DOI: 10.1021/jm0503291 BindingDB Entry DOI: 10.7270/Q2PN96DN |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50162708
(3-(5-fluoro-1H-indol-3-yl)-N,N-dimethylpropan-1-am...)Show InChI InChI=1S/C13H17FN2/c1-16(2)7-3-4-10-9-15-13-6-5-11(14)8-12(10)13/h5-6,8-9,15H,3-4,7H2,1-2H3 | PDB
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| 4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description Binding inhibition towards human serotonin transporter |
J Med Chem 48: 6023-34 (2005)
Article DOI: 10.1021/jm0503291 BindingDB Entry DOI: 10.7270/Q2PN96DN |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50173706
(3-((1R,2S)-2-Dimethylaminomethyl-cyclopropyl)-1H-i...)Show InChI InChI=1S/C15H17N3/c1-18(2)9-11-6-12(11)14-8-17-15-4-3-10(7-16)5-13(14)15/h3-5,8,11-12,17H,6,9H2,1-2H3/t11-,12-/m1/s1 | PDB
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| Article PubMed
| 5.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description Binding inhibition towards human serotonin transporter |
J Med Chem 48: 6023-34 (2005)
Article DOI: 10.1021/jm0503291 BindingDB Entry DOI: 10.7270/Q2PN96DN |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50173713
(3-((1S,2S)-2-Dimethylaminomethyl-cyclopropyl)-1-me...)Show InChI InChI=1S/C16H19N3/c1-18(2)9-12-7-13(12)15-10-19(3)16-5-4-11(8-17)6-14(15)16/h4-6,10,12-13H,7,9H2,1-3H3/t12-,13+/m1/s1 | PDB
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| 6.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description Binding inhibition towards human serotonin transporter |
J Med Chem 48: 6023-34 (2005)
Article DOI: 10.1021/jm0503291 BindingDB Entry DOI: 10.7270/Q2PN96DN |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50173709
(3-((1S,2S)-2-Dimethylaminomethyl-cyclopropyl)-1H-i...)Show InChI InChI=1S/C15H17N3/c1-18(2)9-11-6-13(11)14-8-17-15-5-10(7-16)3-4-12(14)15/h3-5,8,11,13,17H,6,9H2,1-2H3/t11-,13+/m1/s1 | PDB
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| 7.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description Binding inhibition towards human serotonin transporter |
J Med Chem 48: 6023-34 (2005)
Article DOI: 10.1021/jm0503291 BindingDB Entry DOI: 10.7270/Q2PN96DN |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50173705
((-)3-((1R,2R)-2-Dimethylaminomethyl-cyclopropyl)-1...)Show InChI InChI=1S/C15H17N3/c1-18(2)9-11-6-12(11)14-8-17-15-4-3-10(7-16)5-13(14)15/h3-5,8,11-12,17H,6,9H2,1-2H3/t11-,12+/m0/s1 | PDB
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| 8.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description Binding inhibition towards human serotonin transporter |
J Med Chem 48: 6023-34 (2005)
Article DOI: 10.1021/jm0503291 BindingDB Entry DOI: 10.7270/Q2PN96DN |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50173714
(CHEMBL364050 | [(1S,2S)-2-(7-Fluoro-1H-indol-3-yl)...)Show InChI InChI=1S/C14H17FN2/c1-17(2)8-9-6-11(9)12-7-16-14-10(12)4-3-5-13(14)15/h3-5,7,9,11,16H,6,8H2,1-2H3/t9-,11+/m1/s1 | PDB
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| Article PubMed
| 10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description Binding inhibition towards human serotonin transporter |
J Med Chem 48: 6023-34 (2005)
Article DOI: 10.1021/jm0503291 BindingDB Entry DOI: 10.7270/Q2PN96DN |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50173711
((+)3-((1S,2R)-2-Dimethylaminomethyl-cyclopropyl)-1...)Show InChI InChI=1S/C15H17N3/c1-18(2)9-11-6-12(11)14-8-17-15-4-3-10(7-16)5-13(14)15/h3-5,8,11-12,17H,6,9H2,1-2H3/t11-,12-/m0/s1 | PDB
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| 17 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description Binding inhibition towards human serotonin transporter |
J Med Chem 48: 6023-34 (2005)
Article DOI: 10.1021/jm0503291 BindingDB Entry DOI: 10.7270/Q2PN96DN |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50173703
((-)[(1R,2S)-2-(5-Fluoro-1H-indol-3-yl)-cyclopropyl...)Show InChI InChI=1S/C14H17FN2/c1-17(2)8-9-5-11(9)13-7-16-14-4-3-10(15)6-12(13)14/h3-4,6-7,9,11,16H,5,8H2,1-2H3/t9-,11-/m0/s1 | PDB
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| Article PubMed
| 24 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description Binding inhibition towards human serotonin transporter |
J Med Chem 48: 6023-34 (2005)
Article DOI: 10.1021/jm0503291 BindingDB Entry DOI: 10.7270/Q2PN96DN |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50173703
((-)[(1R,2S)-2-(5-Fluoro-1H-indol-3-yl)-cyclopropyl...)Show InChI InChI=1S/C14H17FN2/c1-17(2)8-9-5-11(9)13-7-16-14-4-3-10(15)6-12(13)14/h3-4,6-7,9,11,16H,5,8H2,1-2H3/t9-,11-/m0/s1 | PDB
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| 24 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description Binding inhibition towards human serotonin transporter |
J Med Chem 48: 6023-34 (2005)
Article DOI: 10.1021/jm0503291 BindingDB Entry DOI: 10.7270/Q2PN96DN |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50173701
(CHEMBL194960 | [(1S,2S)-2-(6-Fluoro-1H-indol-3-yl)...)Show InChI InChI=1S/C14H17FN2/c1-17(2)8-9-5-12(9)13-7-16-14-6-10(15)3-4-11(13)14/h3-4,6-7,9,12,16H,5,8H2,1-2H3/t9-,12+/m1/s1 | PDB
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| 38 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description Binding inhibition towards human serotonin transporter |
J Med Chem 48: 6023-34 (2005)
Article DOI: 10.1021/jm0503291 BindingDB Entry DOI: 10.7270/Q2PN96DN |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50173704
((-)[(1R,2R)-2-(5-Fluoro-1H-indol-3-yl)-cyclopropyl...)Show InChI InChI=1S/C14H17FN2/c1-17(2)8-9-5-11(9)13-7-16-14-4-3-10(15)6-12(13)14/h3-4,6-7,9,11,16H,5,8H2,1-2H3/t9-,11+/m0/s1 | PDB
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| 41 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description Binding inhibition towards human serotonin transporter |
J Med Chem 48: 6023-34 (2005)
Article DOI: 10.1021/jm0503291 BindingDB Entry DOI: 10.7270/Q2PN96DN |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50173716
(CHEMBL194909 | [(1S,2S)-2-(4-Fluoro-1H-indol-3-yl)...)Show InChI InChI=1S/C14H17FN2/c1-17(2)8-9-6-10(9)11-7-16-13-5-3-4-12(15)14(11)13/h3-5,7,9-10,16H,6,8H2,1-2H3/t9-,10+/m1/s1 | PDB
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| 59 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description Binding inhibition towards human serotonin transporter |
J Med Chem 48: 6023-34 (2005)
Article DOI: 10.1021/jm0503291 BindingDB Entry DOI: 10.7270/Q2PN96DN |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM22416
((3S,4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-f...)Show SMILES Fc1ccc(cc1)[C@@H]1CCNC[C@H]1COc1ccc2OCOc2c1 Show InChI InChI=1S/C19H20FNO3/c20-15-3-1-13(2-4-15)17-7-8-21-10-14(17)11-22-16-5-6-18-19(9-16)24-12-23-18/h1-6,9,14,17,21H,7-8,10-12H2/t14-,17-/m0/s1 | Reactome pathway KEGG
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| DrugBank Article PubMed
| 90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description Binding inhibition towards human norepinephrine transporter |
J Med Chem 48: 6023-34 (2005)
Article DOI: 10.1021/jm0503291 BindingDB Entry DOI: 10.7270/Q2PN96DN |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50173707
((+)[(1S,2R)-2-(5-Fluoro-1H-indol-3-yl)-cyclopropyl...)Show InChI InChI=1S/C14H17FN2/c1-17(2)8-9-5-11(9)13-7-16-14-4-3-10(15)6-12(13)14/h3-4,6-7,9,11,16H,5,8H2,1-2H3/t9-,11-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description Binding inhibition towards human serotonin transporter |
J Med Chem 48: 6023-34 (2005)
Article DOI: 10.1021/jm0503291 BindingDB Entry DOI: 10.7270/Q2PN96DN |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50173702
(3-((1S,2S)-2-Dimethylaminomethyl-cyclopropyl)-1H-i...)Show InChI InChI=1S/C15H17N3/c1-18(2)9-11-6-12(11)13-8-17-14-5-3-4-10(7-16)15(13)14/h3-5,8,11-12,17H,6,9H2,1-2H3/t11-,12+/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 230 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description Binding inhibition towards human serotonin transporter |
J Med Chem 48: 6023-34 (2005)
Article DOI: 10.1021/jm0503291 BindingDB Entry DOI: 10.7270/Q2PN96DN |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50173702
(3-((1S,2S)-2-Dimethylaminomethyl-cyclopropyl)-1H-i...)Show InChI InChI=1S/C15H17N3/c1-18(2)9-11-6-12(11)13-8-17-14-5-3-4-10(7-16)15(13)14/h3-5,8,11-12,17H,6,9H2,1-2H3/t11-,12+/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 230 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description Binding inhibition towards human serotonin transporter |
J Med Chem 48: 6023-34 (2005)
Article DOI: 10.1021/jm0503291 BindingDB Entry DOI: 10.7270/Q2PN96DN |
More data for this Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM22416
((3S,4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-f...)Show SMILES Fc1ccc(cc1)[C@@H]1CCNC[C@H]1COc1ccc2OCOc2c1 Show InChI InChI=1S/C19H20FNO3/c20-15-3-1-13(2-4-15)17-7-8-21-10-14(17)11-22-16-5-6-18-19(9-16)24-12-23-18/h1-6,9,14,17,21H,7-8,10-12H2/t14-,17-/m0/s1 | NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| 400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description Binding inhibition towards human dopamine transporter |
J Med Chem 48: 6023-34 (2005)
Article DOI: 10.1021/jm0503291 BindingDB Entry DOI: 10.7270/Q2PN96DN |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM30130
(CHEMBL1201082 | CHEMBL41 | Fluoxetin | Fluoxetine ...)Show InChI InChI=1S/C17H18F3NO/c1-21-12-11-16(13-5-3-2-4-6-13)22-15-9-7-14(8-10-15)17(18,19)20/h2-10,16,21H,11-12H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL DrugBank MCE PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| 440 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description Binding inhibition towards human norepinephrine transporter |
J Med Chem 48: 6023-34 (2005)
Article DOI: 10.1021/jm0503291 BindingDB Entry DOI: 10.7270/Q2PN96DN |
More data for this Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM30130
(CHEMBL1201082 | CHEMBL41 | Fluoxetin | Fluoxetine ...)Show InChI InChI=1S/C17H18F3NO/c1-21-12-11-16(13-5-3-2-4-6-13)22-15-9-7-14(8-10-15)17(18,19)20/h2-10,16,21H,11-12H2,1H3 | NCI pathway Reactome pathway KEGG
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| Article PubMed
| 1.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description Binding inhibition towards human dopamine transporter |
J Med Chem 48: 6023-34 (2005)
Article DOI: 10.1021/jm0503291 BindingDB Entry DOI: 10.7270/Q2PN96DN |
More data for this Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50173715
((+)3-((1S,2S)-2-Dimethylaminomethyl-cyclopropyl)-1...)Show InChI InChI=1S/C15H17N3/c1-18(2)9-11-6-12(11)14-8-17-15-4-3-10(7-16)5-13(14)15/h3-5,8,11-12,17H,6,9H2,1-2H3/t11-,12+/m1/s1 | NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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CHEMBL PC cid PC sid UniChem
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| Article PubMed
| 2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description Binding inhibition towards human dopamine transporter |
J Med Chem 48: 6023-34 (2005)
Article DOI: 10.1021/jm0503291 BindingDB Entry DOI: 10.7270/Q2PN96DN |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50173715
((+)3-((1S,2S)-2-Dimethylaminomethyl-cyclopropyl)-1...)Show InChI InChI=1S/C15H17N3/c1-18(2)9-11-6-12(11)14-8-17-15-4-3-10(7-16)5-13(14)15/h3-5,8,11-12,17H,6,9H2,1-2H3/t11-,12+/m1/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
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| Article PubMed
| 4.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description In vitro binding affinity towards human norepinephrine transporter |
J Med Chem 48: 6023-34 (2005)
Article DOI: 10.1021/jm0503291 BindingDB Entry DOI: 10.7270/Q2PN96DN |
More data for this Ligand-Target Pair | |
Cytochrome P450 3A4
(Homo sapiens (Human)) | BDBM50458163
(CHEMBL4209316)Show SMILES CNc1nc(Nc2ccc(c(OC)c2)-n2cnc(C)n2)nc2[C@@H](CCc12)c1ccc(F)cc1 |r| Show InChI InChI=1S/C24H24FN7O/c1-14-27-13-32(31-14)20-11-8-17(12-21(20)33-3)28-24-29-22-18(15-4-6-16(25)7-5-15)9-10-19(22)23(26-2)30-24/h4-8,11-13,18H,9-10H2,1-3H3,(H2,26,28,29,30)/t18-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 8.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Time dependent inhibition of CYP3A4 in human liver microsomes assessed as inhibition constant |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.8b00541 BindingDB Entry DOI: 10.7270/Q24171P7 |
More data for this Ligand-Target Pair | |
Presenilin-1
(Homo sapiens (Human)) | BDBM50485806
(CHEMBL2164125)Show SMILES COc1ccc(CN([C@H](CC(C)C)C(N)=O)S(=O)(=O)c2ccc(Cl)cc2)cc1 |r| Show InChI InChI=1S/C20H25ClN2O4S/c1-14(2)12-19(20(22)24)23(13-15-4-8-17(27-3)9-5-15)28(25,26)18-10-6-16(21)7-11-18/h4-11,14,19H,12-13H2,1-3H3,(H2,22,24)/t19-/m1/s1 | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 0.190 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb R&D
Curated by ChEMBL
| Assay Description Inhibition of human gamma-secretase expressed in IMR32 cell membranes using MBPC-125 Swedish as substrate assessed as inhibition of amyloid beta40 pr... |
Bioorg Med Chem Lett 22: 6828-31 (2012)
Article DOI: 10.1016/j.bmcl.2012.09.057 BindingDB Entry DOI: 10.7270/Q2RJ4NBT |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50173715
((+)3-((1S,2S)-2-Dimethylaminomethyl-cyclopropyl)-1...)Show InChI InChI=1S/C15H17N3/c1-18(2)9-11-6-12(11)14-8-17-15-4-3-10(7-16)5-13(14)15/h3-5,8,11-12,17H,6,9H2,1-2H3/t11-,12+/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 0.480 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description Inhibition of human SERT |
Bioorg Med Chem Lett 17: 5647-51 (2007)
Article DOI: 10.1016/j.bmcl.2007.07.083 BindingDB Entry DOI: 10.7270/Q2KP82Z6 |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50173705
((-)3-((1R,2R)-2-Dimethylaminomethyl-cyclopropyl)-1...)Show InChI InChI=1S/C15H17N3/c1-18(2)9-11-6-12(11)14-8-17-15-4-3-10(7-16)5-13(14)15/h3-5,8,11-12,17H,6,9H2,1-2H3/t11-,12+/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description Inhibition of human SERT |
Bioorg Med Chem Lett 17: 5647-51 (2007)
Article DOI: 10.1016/j.bmcl.2007.07.083 BindingDB Entry DOI: 10.7270/Q2KP82Z6 |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50162700
(3-(3-(dimethylamino)propyl)-1H-indole-5-carbonitri...)Show InChI InChI=1S/C14H17N3/c1-17(2)7-3-4-12-10-16-14-6-5-11(9-15)8-13(12)14/h5-6,8,10,16H,3-4,7H2,1-2H3 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description Inhibition of human SERT |
Bioorg Med Chem Lett 17: 5647-51 (2007)
Article DOI: 10.1016/j.bmcl.2007.07.083 BindingDB Entry DOI: 10.7270/Q2KP82Z6 |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50162708
(3-(5-fluoro-1H-indol-3-yl)-N,N-dimethylpropan-1-am...)Show InChI InChI=1S/C13H17FN2/c1-16(2)7-3-4-10-9-15-13-6-5-11(14)8-12(10)13/h5-6,8-9,15H,3-4,7H2,1-2H3 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description Inhibition of human SERT |
Bioorg Med Chem Lett 17: 5647-51 (2007)
Article DOI: 10.1016/j.bmcl.2007.07.083 BindingDB Entry DOI: 10.7270/Q2KP82Z6 |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50173717
(((1S,2S)-2-(5-fluoro-1H-indol-3-yl)cyclopropyl)-N,...)Show InChI InChI=1S/C14H17FN2/c1-17(2)8-9-5-11(9)13-7-16-14-4-3-10(15)6-12(13)14/h3-4,6-7,9,11,16H,5,8H2,1-2H3/t9-,11+/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 4.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description Inhibition of human SERT |
Bioorg Med Chem Lett 17: 5647-51 (2007)
Article DOI: 10.1016/j.bmcl.2007.07.083 BindingDB Entry DOI: 10.7270/Q2KP82Z6 |
More data for this Ligand-Target Pair | |
Presenilin-1
(Homo sapiens (Human)) | BDBM50477715
(CHEMBL248647)Show SMILES COc1ccc(CN([C@@H]2CCCCNC2=O)S(=O)(=O)c2ccc(Cl)cc2)cc1 Show InChI InChI=1S/C20H23ClN2O4S/c1-27-17-9-5-15(6-10-17)14-23(19-4-2-3-13-22-20(19)24)28(25,26)18-11-7-16(21)8-12-18/h5-12,19H,2-4,13-14H2,1H3,(H,22,24)/t19-/m1/s1 | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 4.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb R&D
Curated by ChEMBL
| Assay Description Inhibition of gamma-secretase in human H4 cells expressing APP751 Swedish mutant assessed as inhibition of amyloid beta40 production after 19 hrs |
Bioorg Med Chem Lett 22: 6828-31 (2012)
Article DOI: 10.1016/j.bmcl.2012.09.057 BindingDB Entry DOI: 10.7270/Q2RJ4NBT |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50220645
(5-(2-((dimethylamino)methyl)cyclopropyl)-2-naphtho...)Show InChI InChI=1S/C17H18N2/c1-19(2)11-14-9-17(14)16-5-3-4-13-8-12(10-18)6-7-15(13)16/h3-8,14,17H,9,11H2,1-2H3 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 4.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description Inhibition of human SERT |
Bioorg Med Chem Lett 17: 5647-51 (2007)
Article DOI: 10.1016/j.bmcl.2007.07.083 BindingDB Entry DOI: 10.7270/Q2KP82Z6 |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50220664
(6-(2-((dimethylamino)methyl)cyclopropyl)naphthalen...)Show SMILES CN(C)CC1CC1c1ccc2cc(C#N)c(cc2c1)C#N |w:4.3,6.7| Show InChI InChI=1S/C18H17N3/c1-21(2)11-17-8-18(17)13-4-3-12-5-15(9-19)16(10-20)7-14(12)6-13/h3-7,17-18H,8,11H2,1-2H3 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 5.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description Inhibition of human SERT |
Bioorg Med Chem Lett 17: 5647-51 (2007)
Article DOI: 10.1016/j.bmcl.2007.07.083 BindingDB Entry DOI: 10.7270/Q2KP82Z6 |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50220657
(6-(2-((dimethylamino)methyl)cyclopropyl)-2-naphtho...)Show InChI InChI=1S/C17H18N2/c1-19(2)11-16-9-17(16)15-6-5-13-7-12(10-18)3-4-14(13)8-15/h3-8,16-17H,9,11H2,1-2H3 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description Inhibition of human SERT |
Bioorg Med Chem Lett 17: 5647-51 (2007)
Article DOI: 10.1016/j.bmcl.2007.07.083 BindingDB Entry DOI: 10.7270/Q2KP82Z6 |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50220660
(5-(2-((benzyl(methyl)amino)methyl)cyclopropyl)-2-n...)Show SMILES CN(CC1CC1c1cccc2cc(ccc12)C#N)Cc1ccccc1 |w:3.2,5.6| Show InChI InChI=1S/C23H22N2/c1-25(15-17-6-3-2-4-7-17)16-20-13-23(20)22-9-5-8-19-12-18(14-24)10-11-21(19)22/h2-12,20,23H,13,15-16H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description Inhibition of human SERT |
Bioorg Med Chem Lett 17: 5647-51 (2007)
Article DOI: 10.1016/j.bmcl.2007.07.083 BindingDB Entry DOI: 10.7270/Q2KP82Z6 |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50220646
(5-(2-((methylamino)methyl)cyclopropyl)-2-naphthoni...)Show InChI InChI=1S/C16H16N2/c1-18-10-13-8-16(13)15-4-2-3-12-7-11(9-17)5-6-14(12)15/h2-7,13,16,18H,8,10H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description Inhibition of human SERT |
Bioorg Med Chem Lett 17: 5647-51 (2007)
Article DOI: 10.1016/j.bmcl.2007.07.083 BindingDB Entry DOI: 10.7270/Q2KP82Z6 |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50220651
(CHEMBL399147 | N,N-dimethyl(2-(naphthalen-1-yl)cyc...)Show InChI InChI=1S/C16H19N/c1-17(2)11-13-10-16(13)15-9-5-7-12-6-3-4-8-14(12)15/h3-9,13,16H,10-11H2,1-2H3 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description Inhibition of human SERT |
Bioorg Med Chem Lett 17: 5647-51 (2007)
Article DOI: 10.1016/j.bmcl.2007.07.083 BindingDB Entry DOI: 10.7270/Q2KP82Z6 |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50220659
(5-(2-((ethylamino)methyl)cyclopropyl)-2-naphthonit...)Show InChI InChI=1S/C17H18N2/c1-2-19-11-14-9-17(14)16-5-3-4-13-8-12(10-18)6-7-15(13)16/h3-8,14,17,19H,2,9,11H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 37 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description Inhibition of human SERT |
Bioorg Med Chem Lett 17: 5647-51 (2007)
Article DOI: 10.1016/j.bmcl.2007.07.083 BindingDB Entry DOI: 10.7270/Q2KP82Z6 |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50220654
(5-(2-((dimethylamino)methyl)cyclopropyl)-1-naphtho...)Show InChI InChI=1S/C17H18N2/c1-19(2)11-13-9-17(13)16-8-4-6-14-12(10-18)5-3-7-15(14)16/h3-8,13,17H,9,11H2,1-2H3 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 48 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description Inhibition of human SERT |
Bioorg Med Chem Lett 17: 5647-51 (2007)
Article DOI: 10.1016/j.bmcl.2007.07.083 BindingDB Entry DOI: 10.7270/Q2KP82Z6 |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50220667
(5-(2-(pyrrolidin-1-ylmethyl)cyclopropyl)-2-naphtho...)Show SMILES N#Cc1ccc2c(cccc2c1)C1CC1CN1CCCC1 |w:14.17,12.13| Show InChI InChI=1S/C19H20N2/c20-12-14-6-7-17-15(10-14)4-3-5-18(17)19-11-16(19)13-21-8-1-2-9-21/h3-7,10,16,19H,1-2,8-9,11,13H2 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 51 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description Inhibition of human SERT |
Bioorg Med Chem Lett 17: 5647-51 (2007)
Article DOI: 10.1016/j.bmcl.2007.07.083 BindingDB Entry DOI: 10.7270/Q2KP82Z6 |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50220666
(CHEMBL249331 | N-methyl(2-(naphthalen-2-yl)cyclopr...)Show InChI InChI=1S/C15H17N/c1-16-10-14-9-15(14)13-7-6-11-4-2-3-5-12(11)8-13/h2-8,14-16H,9-10H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 52 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description Inhibition of human SERT |
Bioorg Med Chem Lett 17: 5647-51 (2007)
Article DOI: 10.1016/j.bmcl.2007.07.083 BindingDB Entry DOI: 10.7270/Q2KP82Z6 |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50220661
((2-(benzo[b]thiophen-3-yl)cyclopropyl)-N,N-dimethy...)Show InChI InChI=1S/C14H17NS/c1-15(2)8-10-7-12(10)13-9-16-14-6-4-3-5-11(13)14/h3-6,9-10,12H,7-8H2,1-2H3 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 55 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description Inhibition of human SERT |
Bioorg Med Chem Lett 17: 5647-51 (2007)
Article DOI: 10.1016/j.bmcl.2007.07.083 BindingDB Entry DOI: 10.7270/Q2KP82Z6 |
More data for this Ligand-Target Pair | |