Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Neuronal acetylcholine receptor subunit alpha-4 (Rattus norvegicus (Rat)) | BDBM50049757 (()-2-(6-Chloro-pyridin-3-yl)-7-aza-bicyclo[2.2.1]h...) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 0.0470 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Displacement of [3H]cytisine from alpha4beta2 nAChR in rat brain membrane | Bioorg Med Chem Lett 19: 1682-5 (2009) Article DOI: 10.1016/j.bmcl.2009.01.099 BindingDB Entry DOI: 10.7270/Q2HD7VJK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuronal acetylcholine receptor subunit alpha-4 (Rattus norvegicus (Rat)) | BDBM50062641 (5-((R)-1-Azetidin-2-ylmethoxy)-2-chloro-pyridine |...) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 0.0480 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Displacement of [3H]cytisine from alpha4beta2 nAChR in rat brain membrane | Bioorg Med Chem Lett 19: 1682-5 (2009) Article DOI: 10.1016/j.bmcl.2009.01.099 BindingDB Entry DOI: 10.7270/Q2HD7VJK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estrogen receptor (Homo sapiens (Human)) | BDBM50212159 (2-(4-isopropylphenyl)-3-(4-(2-(piperidin-1-yl)etho...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.0910 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Displacement of [3H]estradiol from human recombinant ERalpha | Bioorg Med Chem Lett 17: 3544-9 (2007) Article DOI: 10.1016/j.bmcl.2007.04.044 BindingDB Entry DOI: 10.7270/Q2ZS2W6F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human)) | BDBM202351 (US9238619, 70) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | <0.100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent | Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171... | US Patent US9238619 (2016) BindingDB Entry DOI: 10.7270/Q2XS5T6F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human)) | BDBM202353 (US9238619, 72) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | <0.100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent | Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171... | US Patent US9238619 (2016) BindingDB Entry DOI: 10.7270/Q2XS5T6F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human)) | BDBM202356 (US9238619, 73) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | <0.100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent | Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171... | US Patent US9238619 (2016) BindingDB Entry DOI: 10.7270/Q2XS5T6F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human)) | BDBM202358 (US9238619, 75) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | <0.100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent | Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171... | US Patent US9238619 (2016) BindingDB Entry DOI: 10.7270/Q2XS5T6F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human)) | BDBM202359 (US9238619, 76) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | <0.100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent | Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171... | US Patent US9238619 (2016) BindingDB Entry DOI: 10.7270/Q2XS5T6F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human)) | BDBM202361 (US9238619, 78) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | <0.100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent | Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171... | US Patent US9238619 (2016) BindingDB Entry DOI: 10.7270/Q2XS5T6F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human)) | BDBM202314 (US9238619, 50) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | <0.100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent | Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171... | US Patent US9238619 (2016) BindingDB Entry DOI: 10.7270/Q2XS5T6F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human)) | BDBM202238 (US9238619, 3) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | <0.100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent | Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171... | US Patent US9238619 (2016) BindingDB Entry DOI: 10.7270/Q2XS5T6F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human)) | BDBM202239 (US9238619, 4) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | <0.100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent | Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171... | US Patent US9238619 (2016) BindingDB Entry DOI: 10.7270/Q2XS5T6F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human)) | BDBM202240 (US9238619, 5) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | <0.100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent | Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171... | US Patent US9238619 (2016) BindingDB Entry DOI: 10.7270/Q2XS5T6F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human)) | BDBM202241 (US9238619, 6) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | <0.100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent | Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171... | US Patent US9238619 (2016) BindingDB Entry DOI: 10.7270/Q2XS5T6F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human)) | BDBM202247 (US9238619, 10) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | <0.100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent | Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171... | US Patent US9238619 (2016) BindingDB Entry DOI: 10.7270/Q2XS5T6F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human)) | BDBM202249 (US9238619, 12) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | <0.100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent | Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171... | US Patent US9238619 (2016) BindingDB Entry DOI: 10.7270/Q2XS5T6F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human)) | BDBM202260 (US9238619, 18) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | <0.100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent | Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171... | US Patent US9238619 (2016) BindingDB Entry DOI: 10.7270/Q2XS5T6F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human)) | BDBM202265 (US9238619, 23) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | <0.100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent | Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171... | US Patent US9238619 (2016) BindingDB Entry DOI: 10.7270/Q2XS5T6F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human)) | BDBM202266 (US9238619, 24) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | <0.100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent | Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171... | US Patent US9238619 (2016) BindingDB Entry DOI: 10.7270/Q2XS5T6F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human)) | BDBM202271 (US9238619, 29) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | <0.100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent | Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171... | US Patent US9238619 (2016) BindingDB Entry DOI: 10.7270/Q2XS5T6F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human)) | BDBM202272 (US9238619, 30) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | <0.100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent | Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171... | US Patent US9238619 (2016) BindingDB Entry DOI: 10.7270/Q2XS5T6F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human)) | BDBM202274 (US9238619, 32) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | <0.100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent | Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171... | US Patent US9238619 (2016) BindingDB Entry DOI: 10.7270/Q2XS5T6F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human)) | BDBM202275 (US9238619, 33) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | <0.100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent | Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171... | US Patent US9238619 (2016) BindingDB Entry DOI: 10.7270/Q2XS5T6F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human)) | BDBM202270 (US9238619, 28) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | <0.100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent | Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171... | US Patent US9238619 (2016) BindingDB Entry DOI: 10.7270/Q2XS5T6F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human)) | BDBM202273 (US9238619, 31) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | <0.100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent | Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171... | US Patent US9238619 (2016) BindingDB Entry DOI: 10.7270/Q2XS5T6F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human)) | BDBM202315 (US9238619, 51) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | <0.100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent | Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171... | US Patent US9238619 (2016) BindingDB Entry DOI: 10.7270/Q2XS5T6F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human)) | BDBM202335 (US9238619, 60) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | <0.100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent | Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171... | US Patent US9238619 (2016) BindingDB Entry DOI: 10.7270/Q2XS5T6F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human)) | BDBM202341 (US9238619, 63) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | <0.100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent | Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171... | US Patent US9238619 (2016) BindingDB Entry DOI: 10.7270/Q2XS5T6F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human)) | BDBM202348 (US9238619, 67) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | <0.100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent | Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171... | US Patent US9238619 (2016) BindingDB Entry DOI: 10.7270/Q2XS5T6F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human)) | BDBM202337 (US9238619, 62) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | <0.100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent | Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171... | US Patent US9238619 (2016) BindingDB Entry DOI: 10.7270/Q2XS5T6F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human)) | BDBM202336 (US9238619, 61) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | <0.100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent | Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171... | US Patent US9238619 (2016) BindingDB Entry DOI: 10.7270/Q2XS5T6F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human)) | BDBM202316 (US9238619, 52) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | <0.100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent | Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171... | US Patent US9238619 (2016) BindingDB Entry DOI: 10.7270/Q2XS5T6F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium- and chloride-dependent glycine transporter 1 (Homo sapiens (Human)) | BDBM202334 (US9238619, 59) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | <0.100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Deutschland GmbH & Co. KG; AbbVie Inc. US Patent | Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was determined as described in Mezler et al., Molecular Pharmacology 74:1705-171... | US Patent US9238619 (2016) BindingDB Entry DOI: 10.7270/Q2XS5T6F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1B (Homo sapiens (Human)) | BDBM50175484 (3-[2-(4-isoquinolin-8-yl-piperazin-1-yl)-ethyl]-7-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott GmbH & Co. KG Curated by ChEMBL | Assay Description Inhibitory activity against human recombinant 5HT1B receptor co-expressed with G-protein chimera Gqo5 in HEK293 cells by FLIPR | Bioorg Med Chem Lett 15: 5567-73 (2005) Article DOI: 10.1016/j.bmcl.2005.04.077 BindingDB Entry DOI: 10.7270/Q2CR5SX4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor X (Homo sapiens (Human)) | BDBM50228930 ((E)-2-(6-chloro-benzo[b]thiophen-2-yl)-ethenesulfo...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Inhibition of human F10a by fluorescence assay | Bioorg Med Chem Lett 18: 23-7 (2008) Article DOI: 10.1016/j.bmcl.2007.11.023 BindingDB Entry DOI: 10.7270/Q2SX6CZF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuronal acetylcholine receptor subunit alpha-4 (Rattus norvegicus (Rat)) | BDBM50216347 ((1R,4R)-2-(3-pyridinyl)-2,5-diazabicyclo[2.2.1]hep...) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.150 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Displacement of [3H]cytisine from alpha4beta2 nAChR in rat brain membrane | Bioorg Med Chem Lett 19: 1682-5 (2009) Article DOI: 10.1016/j.bmcl.2009.01.099 BindingDB Entry DOI: 10.7270/Q2HD7VJK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estrogen receptor beta (Homo sapiens (Human)) | BDBM50212148 (6-(3-fluorophenyl)-5-(4-(2-(piperidin-1-yl)ethoxy)...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.160 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Displacement of [3H]estradiol from human recombinant ERbeta | Bioorg Med Chem Lett 17: 3544-9 (2007) Article DOI: 10.1016/j.bmcl.2007.04.044 BindingDB Entry DOI: 10.7270/Q2ZS2W6F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estrogen receptor (Homo sapiens (Human)) | BDBM50212148 (6-(3-fluorophenyl)-5-(4-(2-(piperidin-1-yl)ethoxy)...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.180 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Displacement of [3H]estradiol from human recombinant ERalpha | Bioorg Med Chem Lett 17: 3544-9 (2007) Article DOI: 10.1016/j.bmcl.2007.04.044 BindingDB Entry DOI: 10.7270/Q2ZS2W6F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2 (Homo sapiens (Human)) | BDBM144227 (US8952008, 4) | UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | Article PubMed | 0.180 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Displacement of [3H]-flumazenil from human GABAA alpha1beta3gamma2 receptor expressed in HEK293 cell membranes measured after 2 hrs by liquid scintil... | J Med Chem 62: 5773-5796 (2019) Article DOI: 10.1021/acs.jmedchem.9b00322 BindingDB Entry DOI: 10.7270/Q2HQ437D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transcription initiation factor TFIID subunit 1 (Homo sapiens (Human)) | BDBM50572134 (CHEMBL4868363) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human partial length TAF1 bromodomain 2 (D1521 to D1656 residues) expressed in bacterial expression system by BROMOscan assay | Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00294 BindingDB Entry DOI: 10.7270/Q21V5JRX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estrogen receptor (Homo sapiens (Human)) | BDBM50212157 (6-(3,4-difluorophenyl)-5-(4-(2-(piperidin-1-yl)eth...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Displacement of [3H]estradiol from human recombinant ERalpha | Bioorg Med Chem Lett 17: 3544-9 (2007) Article DOI: 10.1016/j.bmcl.2007.04.044 BindingDB Entry DOI: 10.7270/Q2ZS2W6F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50175479 (7-methyl-3-[2-(4-quinolin-8-yl-piperazin-1-yl)-eth...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott GmbH & Co. KG Curated by ChEMBL | Assay Description Displacement of [35S]GTPgammaS from human recombinant 5HT1A receptor | Bioorg Med Chem Lett 15: 5567-73 (2005) Article DOI: 10.1016/j.bmcl.2005.04.077 BindingDB Entry DOI: 10.7270/Q2CR5SX4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor X (Homo sapiens (Human)) | BDBM50228950 ((E)-2-(5-chloro-thiophen-2-yl)-ethenesulfonic acid...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Inhibition of human F10a by fluorescence assay | Bioorg Med Chem Lett 18: 23-7 (2008) Article DOI: 10.1016/j.bmcl.2007.11.023 BindingDB Entry DOI: 10.7270/Q2SX6CZF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estrogen receptor (Homo sapiens (Human)) | BDBM19964 (6-(4-hydroxyphenyl)-5-({4-[2-(piperidin-1-yl)ethox...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents | Article PubMed | 0.200 | -54.8 | n/a | n/a | 1.14 | n/a | n/a | 7.5 | 22 |
Lilly Research Laboratories | Assay Description The binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer. The Kd for 3H-estradiol was determin... | J Med Chem 48: 6772-5 (2005) Article DOI: 10.1021/jm050723z BindingDB Entry DOI: 10.7270/Q2RR1WHW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estrogen receptor (Homo sapiens (Human)) | BDBM50212149 (6-(3-hydroxyphenyl)-5-(4-(2-(piperidin-1-yl)ethoxy...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 0.210 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Displacement of [3H]estradiol from human recombinant ERalpha | Bioorg Med Chem Lett 17: 3544-9 (2007) Article DOI: 10.1016/j.bmcl.2007.04.044 BindingDB Entry DOI: 10.7270/Q2ZS2W6F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estrogen receptor (Homo sapiens (Human)) | BDBM19967 (6-(4-fluorophenyl)-5-{4-[2-(piperidin-1-yl)ethoxy]...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.240 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Displacement of [3H]estradiol from human recombinant ERalpha | Bioorg Med Chem Lett 17: 3544-9 (2007) Article DOI: 10.1016/j.bmcl.2007.04.044 BindingDB Entry DOI: 10.7270/Q2ZS2W6F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estrogen receptor (Homo sapiens (Human)) | BDBM50212160 (3-(6-hydroxy-1-(4-(2-(piperidin-1-yl)ethoxy)phenox...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 0.240 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Displacement of [3H]estradiol from human recombinant ERalpha | Bioorg Med Chem Lett 17: 3544-9 (2007) Article DOI: 10.1016/j.bmcl.2007.04.044 BindingDB Entry DOI: 10.7270/Q2ZS2W6F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estrogen receptor (Homo sapiens (Human)) | BDBM19967 (6-(4-fluorophenyl)-5-{4-[2-(piperidin-1-yl)ethoxy]...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.25 | -54.3 | n/a | n/a | 3.18 | n/a | n/a | 7.5 | 22 |
Lilly Research Laboratories | Assay Description The binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer. The Kd for 3H-estradiol was determin... | J Med Chem 48: 6772-5 (2005) Article DOI: 10.1021/jm050723z BindingDB Entry DOI: 10.7270/Q2RR1WHW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estrogen receptor beta (Homo sapiens (Human)) | BDBM19967 (6-(4-fluorophenyl)-5-{4-[2-(piperidin-1-yl)ethoxy]...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.280 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Displacement of [3H]estradiol from human recombinant ERbeta | Bioorg Med Chem Lett 17: 3544-9 (2007) Article DOI: 10.1016/j.bmcl.2007.04.044 BindingDB Entry DOI: 10.7270/Q2ZS2W6F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estrogen receptor beta (Homo sapiens (Human)) | BDBM50212157 (6-(3,4-difluorophenyl)-5-(4-(2-(piperidin-1-yl)eth...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 0.290 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Displacement of [3H]estradiol from human recombinant ERbeta | Bioorg Med Chem Lett 17: 3544-9 (2007) Article DOI: 10.1016/j.bmcl.2007.04.044 BindingDB Entry DOI: 10.7270/Q2ZS2W6F | |||||||||||
More data for this Ligand-Target Pair |
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