Compile Data Set for Download or QSAR

Found 119 hits with Last Name = 'kansagara' and Initial = 'm'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM50254419 (CHEMBL511391 | N2-(2,6-dichlorophenyl)-N7-(4-(pyrr...) Show SMILES Clc1cccc(Cl)c1Nc1nc2c(Nc3ccc(cc3)S(=O)(=O)N3CCCC3)ncnc2s1 Show InChI InChI=1S/C21H18Cl2N6O2S2/c22-15-4-3-5-16(23)17(15)27-21-28-18-19(24-12-25-20(18)32-21)26-13-6-8-14(9-7-13)33(30,31)29-10-1-2-11-29/h3-9,12H,1-2,10-11H2,(H,27,28)(H,24,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL					Assay Description Antagonist activity at rat TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium flux				Bioorg Med Chem Lett 19: 40-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.024 BindingDB Entry DOI: 10.7270/Q28052G3
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM50254080 ((3,5-dichloro-4-(7-(4-(trifluoromethyl)phenylamino...) Show SMILES OCc1cc(Cl)c(Nc2nc3c(Nc4ccc(cc4)C(F)(F)F)ncnc3s2)c(Cl)c1 Show InChI InChI=1S/C19H12Cl2F3N5OS/c20-12-5-9(7-30)6-13(21)14(12)28-18-29-15-16(25-8-26-17(15)31-18)27-11-3-1-10(2-4-11)19(22,23)24/h1-6,8,30H,7H2,(H,28,29)(H,25,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL					Assay Description Antagonist activity at rat TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium flux				Bioorg Med Chem Lett 19: 40-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.024 BindingDB Entry DOI: 10.7270/Q28052G3
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50254419 (CHEMBL511391 | N2-(2,6-dichlorophenyl)-N7-(4-(pyrr...) Show SMILES Clc1cccc(Cl)c1Nc1nc2c(Nc3ccc(cc3)S(=O)(=O)N3CCCC3)ncnc2s1 Show InChI InChI=1S/C21H18Cl2N6O2S2/c22-15-4-3-5-16(23)17(15)27-21-28-18-19(24-12-25-20(18)32-21)26-13-6-8-14(9-7-13)33(30,31)29-10-1-2-11-29/h3-9,12H,1-2,10-11H2,(H,27,28)(H,24,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL					Assay Description Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium flux				Bioorg Med Chem Lett 19: 40-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.024 BindingDB Entry DOI: 10.7270/Q28052G3
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50254080 ((3,5-dichloro-4-(7-(4-(trifluoromethyl)phenylamino...) Show SMILES OCc1cc(Cl)c(Nc2nc3c(Nc4ccc(cc4)C(F)(F)F)ncnc3s2)c(Cl)c1 Show InChI InChI=1S/C19H12Cl2F3N5OS/c20-12-5-9(7-30)6-13(21)14(12)28-18-29-15-16(25-8-26-17(15)31-18)27-11-3-1-10(2-4-11)19(22,23)24/h1-6,8,30H,7H2,(H,28,29)(H,25,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL					Assay Description Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium flux				Bioorg Med Chem Lett 19: 40-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.024 BindingDB Entry DOI: 10.7270/Q28052G3
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM50254325 (CHEMBL469302 | N7-(4-tert-butylphenyl)-N2-(2,6-dic...) Show SMILES CC(C)(C)c1ccc(Nc2ncnc3sc(Nc4c(Cl)cccc4Cl)nc23)cc1 Show InChI InChI=1S/C21H19Cl2N5S/c1-21(2,3)12-7-9-13(10-8-12)26-18-17-19(25-11-24-18)29-20(28-17)27-16-14(22)5-4-6-15(16)23/h4-11H,1-3H3,(H,27,28)(H,24,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL					Assay Description Antagonist activity at rat TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium flux				Bioorg Med Chem Lett 19: 40-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.024 BindingDB Entry DOI: 10.7270/Q28052G3
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM50254077 (CHEMBL517566 | N2-(2,6-dichlorophenyl)-N5-isobutyl...) Show SMILES CC(C)CNc1nc(Nc2ccc(cc2)C(F)(F)F)c2nc(Nc3c(Cl)cccc3Cl)sc2n1 Show InChI InChI=1S/C22H19Cl2F3N6S/c1-11(2)10-28-20-32-18(29-13-8-6-12(7-9-13)22(25,26)27)17-19(33-20)34-21(31-17)30-16-14(23)4-3-5-15(16)24/h3-9,11H,10H2,1-2H3,(H,30,31)(H2,28,29,32,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL					Assay Description Antagonist activity at rat TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium flux				Bioorg Med Chem Lett 19: 40-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.024 BindingDB Entry DOI: 10.7270/Q28052G3
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM50254154 (CHEMBL468470 | N2-(2-chloro-6-methylphenyl)-N7-(4-...) Show SMILES Cc1cccc(Cl)c1Nc1nc2c(Nc3ccc(cc3)C(F)(F)F)ncnc2s1 Show InChI InChI=1S/C19H13ClF3N5S/c1-10-3-2-4-13(20)14(10)27-18-28-15-16(24-9-25-17(15)29-18)26-12-7-5-11(6-8-12)19(21,22)23/h2-9H,1H3,(H,27,28)(H,24,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL					Assay Description Antagonist activity at rat TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium flux				Bioorg Med Chem Lett 19: 40-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.024 BindingDB Entry DOI: 10.7270/Q28052G3
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50254077 (CHEMBL517566 | N2-(2,6-dichlorophenyl)-N5-isobutyl...) Show SMILES CC(C)CNc1nc(Nc2ccc(cc2)C(F)(F)F)c2nc(Nc3c(Cl)cccc3Cl)sc2n1 Show InChI InChI=1S/C22H19Cl2F3N6S/c1-11(2)10-28-20-32-18(29-13-8-6-12(7-9-13)22(25,26)27)17-19(33-20)34-21(31-17)30-16-14(23)4-3-5-15(16)24/h3-9,11H,10H2,1-2H3,(H,30,31)(H2,28,29,32,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL					Assay Description Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium flux				Bioorg Med Chem Lett 19: 40-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.024 BindingDB Entry DOI: 10.7270/Q28052G3
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM50254421 (CHEMBL465990 | N7-(3-chloro-4-(trifluoromethyl)phe...) Show SMILES Cc1nc(Nc2ccc(c(Cl)c2)C(F)(F)F)c2nc(Nc3c(Cl)cccc3Cl)sc2n1 Show InChI InChI=1S/C19H11Cl3F3N5S/c1-8-26-16(28-9-5-6-10(13(22)7-9)19(23,24)25)15-17(27-8)31-18(30-15)29-14-11(20)3-2-4-12(14)21/h2-7H,1H3,(H,29,30)(H,26,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL					Assay Description Antagonist activity at rat TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium flux				Bioorg Med Chem Lett 19: 40-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.024 BindingDB Entry DOI: 10.7270/Q28052G3
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM50254326 (2-(4-(2-(2,6-dichlorophenylamino)thiazolo[5,4-d]py...) Show SMILES CC(C)(C(O)=O)c1ccc(Nc2ncnc3sc(Nc4c(Cl)cccc4Cl)nc23)cc1 Show InChI InChI=1S/C21H17Cl2N5O2S/c1-21(2,19(29)30)11-6-8-12(9-7-11)26-17-16-18(25-10-24-17)31-20(28-16)27-15-13(22)4-3-5-14(15)23/h3-10H,1-2H3,(H,27,28)(H,29,30)(H,24,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL					Assay Description Antagonist activity at rat TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium flux				Bioorg Med Chem Lett 19: 40-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.024 BindingDB Entry DOI: 10.7270/Q28052G3
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM50254324 (CHEMBL512298 | N2-(2,6-dichlorophenyl)-N7-(4-isopr...) Show SMILES CC(C)c1ccc(Nc2ncnc3sc(Nc4c(Cl)cccc4Cl)nc23)cc1 Show InChI InChI=1S/C20H17Cl2N5S/c1-11(2)12-6-8-13(9-7-12)25-18-17-19(24-10-23-18)28-20(27-17)26-16-14(21)4-3-5-15(16)22/h3-11H,1-2H3,(H,26,27)(H,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL					Assay Description Antagonist activity at rat TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium flux				Bioorg Med Chem Lett 19: 40-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.024 BindingDB Entry DOI: 10.7270/Q28052G3
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM50254136 (CHEMBL469297 | N2-(2,6-dichlorophenyl)-N7-(4-(trif...) Show SMILES FC(F)(F)c1ccc(Nc2ncnc3sc(Nc4c(Cl)cccc4Cl)nc23)cc1 Show InChI InChI=1S/C18H10Cl2F3N5S/c19-11-2-1-3-12(20)13(11)27-17-28-14-15(24-8-25-16(14)29-17)26-10-6-4-9(5-7-10)18(21,22)23/h1-8H,(H,27,28)(H,24,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL					Assay Description Antagonist activity at rat TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium flux				Bioorg Med Chem Lett 19: 40-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.024 BindingDB Entry DOI: 10.7270/Q28052G3
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM50254376 (CHEMBL467851 | N2-(2,6-dichlorophenyl)-N7-(4-(meth...) Show SMILES CS(=O)(=O)c1ccc(Nc2ncnc3sc(Nc4c(Cl)cccc4Cl)nc23)cc1 Show InChI InChI=1S/C18H13Cl2N5O2S2/c1-29(26,27)11-7-5-10(6-8-11)23-16-15-17(22-9-21-16)28-18(25-15)24-14-12(19)3-2-4-13(14)20/h2-9H,1H3,(H,24,25)(H,21,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL					Assay Description Antagonist activity at rat TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium flux				Bioorg Med Chem Lett 19: 40-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.024 BindingDB Entry DOI: 10.7270/Q28052G3
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50254421 (CHEMBL465990 | N7-(3-chloro-4-(trifluoromethyl)phe...) Show SMILES Cc1nc(Nc2ccc(c(Cl)c2)C(F)(F)F)c2nc(Nc3c(Cl)cccc3Cl)sc2n1 Show InChI InChI=1S/C19H11Cl3F3N5S/c1-8-26-16(28-9-5-6-10(13(22)7-9)19(23,24)25)15-17(27-8)31-18(30-15)29-14-11(20)3-2-4-12(14)21/h2-7H,1H3,(H,29,30)(H,26,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL					Assay Description Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium flux				Bioorg Med Chem Lett 19: 40-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.024 BindingDB Entry DOI: 10.7270/Q28052G3
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM50254078 (CHEMBL460373 | N5-(cyclopropylmethyl)-N2-(2,6-dich...) Show SMILES FC(F)(F)c1ccc(Nc2nc(NCC3CC3)nc3sc(Nc4c(Cl)cccc4Cl)nc23)cc1 Show InChI InChI=1S/C22H17Cl2F3N6S/c23-14-2-1-3-15(24)16(14)30-21-31-17-18(29-13-8-6-12(7-9-13)22(25,26)27)32-20(33-19(17)34-21)28-10-11-4-5-11/h1-3,6-9,11H,4-5,10H2,(H,30,31)(H2,28,29,32,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL					Assay Description Antagonist activity at rat TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium flux				Bioorg Med Chem Lett 19: 40-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.024 BindingDB Entry DOI: 10.7270/Q28052G3
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50254078 (CHEMBL460373 | N5-(cyclopropylmethyl)-N2-(2,6-dich...) Show SMILES FC(F)(F)c1ccc(Nc2nc(NCC3CC3)nc3sc(Nc4c(Cl)cccc4Cl)nc23)cc1 Show InChI InChI=1S/C22H17Cl2F3N6S/c23-14-2-1-3-15(24)16(14)30-21-31-17-18(29-13-8-6-12(7-9-13)22(25,26)27)32-20(33-19(17)34-21)28-10-11-4-5-11/h1-3,6-9,11H,4-5,10H2,(H,30,31)(H2,28,29,32,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL					Assay Description Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium flux				Bioorg Med Chem Lett 19: 40-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.024 BindingDB Entry DOI: 10.7270/Q28052G3
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM50254136 (CHEMBL469297 | N2-(2,6-dichlorophenyl)-N7-(4-(trif...) Show SMILES FC(F)(F)c1ccc(Nc2ncnc3sc(Nc4c(Cl)cccc4Cl)nc23)cc1 Show InChI InChI=1S/C18H10Cl2F3N5S/c19-11-2-1-3-12(20)13(11)27-17-28-14-15(24-8-25-16(14)29-17)26-10-6-4-9(5-7-10)18(21,22)23/h1-8H,(H,27,28)(H,24,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL					Assay Description Displacement of [3H]RTX from rat TRPV1 expressed in HEK293 cells				Bioorg Med Chem Lett 19: 40-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.024 BindingDB Entry DOI: 10.7270/Q28052G3
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM50254322 (CHEMBL467007 | N2-(2,6-dichlorophenyl)-N7-(6-(trif...) Show SMILES FC(F)(F)c1ccc(Nc2ncnc3sc(Nc4c(Cl)cccc4Cl)nc23)cn1 Show InChI InChI=1S/C17H9Cl2F3N6S/c18-9-2-1-3-10(19)12(9)27-16-28-13-14(24-7-25-15(13)29-16)26-8-4-5-11(23-6-8)17(20,21)22/h1-7H,(H,27,28)(H,24,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL					Assay Description Antagonist activity at rat TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium flux				Bioorg Med Chem Lett 19: 40-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.024 BindingDB Entry DOI: 10.7270/Q28052G3
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50254376 (CHEMBL467851 | N2-(2,6-dichlorophenyl)-N7-(4-(meth...) Show SMILES CS(=O)(=O)c1ccc(Nc2ncnc3sc(Nc4c(Cl)cccc4Cl)nc23)cc1 Show InChI InChI=1S/C18H13Cl2N5O2S2/c1-29(26,27)11-7-5-10(6-8-11)23-16-15-17(22-9-21-16)28-18(25-15)24-14-12(19)3-2-4-13(14)20/h2-9H,1H3,(H,24,25)(H,21,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL					Assay Description Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium flux				Bioorg Med Chem Lett 19: 40-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.024 BindingDB Entry DOI: 10.7270/Q28052G3
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM50254136 (CHEMBL469297 | N2-(2,6-dichlorophenyl)-N7-(4-(trif...) Show SMILES FC(F)(F)c1ccc(Nc2ncnc3sc(Nc4c(Cl)cccc4Cl)nc23)cc1 Show InChI InChI=1S/C18H10Cl2F3N5S/c19-11-2-1-3-12(20)13(11)27-17-28-14-15(24-8-25-16(14)29-17)26-10-6-4-9(5-7-10)18(21,22)23/h1-8H,(H,27,28)(H,24,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL					Assay Description Antagonist activity at rat TRPV1 expressed in HEK293 cells assessed as inhibition of low pH-induced calcium influx				Bioorg Med Chem Lett 19: 40-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.024 BindingDB Entry DOI: 10.7270/Q28052G3
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM50254153 (CHEMBL511589 | N2-(2,6-dimethylphenyl)-N7-(4-(trif...) Show SMILES Cc1cccc(C)c1Nc1nc2c(Nc3ccc(cc3)C(F)(F)F)ncnc2s1 Show InChI InChI=1S/C20H16F3N5S/c1-11-4-3-5-12(2)15(11)27-19-28-16-17(24-10-25-18(16)29-19)26-14-8-6-13(7-9-14)20(21,22)23/h3-10H,1-2H3,(H,27,28)(H,24,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL					Assay Description Antagonist activity at rat TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium flux				Bioorg Med Chem Lett 19: 40-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.024 BindingDB Entry DOI: 10.7270/Q28052G3
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM50254420 (CHEMBL517044 | N7-(3-chloro-4-(trifluoromethyl)phe...) Show SMILES FC(F)(F)c1ccc(Nc2ncnc3sc(Nc4c(Cl)cccc4Cl)nc23)cc1Cl Show InChI InChI=1S/C18H9Cl3F3N5S/c19-10-2-1-3-11(20)13(10)28-17-29-14-15(25-7-26-16(14)30-17)27-8-4-5-9(12(21)6-8)18(22,23)24/h1-7H,(H,28,29)(H,25,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL					Assay Description Antagonist activity at rat TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium flux				Bioorg Med Chem Lett 19: 40-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.024 BindingDB Entry DOI: 10.7270/Q28052G3
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM50254054 (CHEMBL462276 | N2-(2,6-dichlorophenyl)-N5-isopropy...) Show SMILES CC(C)Nc1nc(Nc2ccc(cc2)C(F)(F)F)c2nc(Nc3c(Cl)cccc3Cl)sc2n1 Show InChI InChI=1S/C21H17Cl2F3N6S/c1-10(2)27-19-31-17(28-12-8-6-11(7-9-12)21(24,25)26)16-18(32-19)33-20(30-16)29-15-13(22)4-3-5-14(15)23/h3-10H,1-2H3,(H,29,30)(H2,27,28,31,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL					Assay Description Antagonist activity at rat TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium flux				Bioorg Med Chem Lett 19: 40-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.024 BindingDB Entry DOI: 10.7270/Q28052G3
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50254154 (CHEMBL468470 | N2-(2-chloro-6-methylphenyl)-N7-(4-...) Show SMILES Cc1cccc(Cl)c1Nc1nc2c(Nc3ccc(cc3)C(F)(F)F)ncnc2s1 Show InChI InChI=1S/C19H13ClF3N5S/c1-10-3-2-4-13(20)14(10)27-18-28-15-16(24-9-25-17(15)29-18)26-12-7-5-11(6-8-12)19(21,22)23/h2-9H,1H3,(H,27,28)(H,24,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL					Assay Description Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium flux				Bioorg Med Chem Lett 19: 40-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.024 BindingDB Entry DOI: 10.7270/Q28052G3
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50254324 (CHEMBL512298 | N2-(2,6-dichlorophenyl)-N7-(4-isopr...) Show SMILES CC(C)c1ccc(Nc2ncnc3sc(Nc4c(Cl)cccc4Cl)nc23)cc1 Show InChI InChI=1S/C20H17Cl2N5S/c1-11(2)12-6-8-13(9-7-12)25-18-17-19(24-10-23-18)28-20(27-17)26-16-14(21)4-3-5-15(16)22/h3-11H,1-2H3,(H,26,27)(H,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL					Assay Description Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium flux				Bioorg Med Chem Lett 19: 40-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.024 BindingDB Entry DOI: 10.7270/Q28052G3
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM50254079 (CHEMBL459320 | N2-(2,6-dichlorophenyl)-N5-(2-morph...) Show SMILES FC(F)(F)c1ccc(Nc2nc(NCCN3CCOCC3)nc3sc(Nc4c(Cl)cccc4Cl)nc23)cc1 Show InChI InChI=1S/C24H22Cl2F3N7OS/c25-16-2-1-3-17(26)18(16)32-23-33-19-20(31-15-6-4-14(5-7-15)24(27,28)29)34-22(35-21(19)38-23)30-8-9-36-10-12-37-13-11-36/h1-7H,8-13H2,(H,32,33)(H2,30,31,34,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL					Assay Description Antagonist activity at rat TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium flux				Bioorg Med Chem Lett 19: 40-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.024 BindingDB Entry DOI: 10.7270/Q28052G3
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50254325 (CHEMBL469302 | N7-(4-tert-butylphenyl)-N2-(2,6-dic...) Show SMILES CC(C)(C)c1ccc(Nc2ncnc3sc(Nc4c(Cl)cccc4Cl)nc23)cc1 Show InChI InChI=1S/C21H19Cl2N5S/c1-21(2,3)12-7-9-13(10-8-12)26-18-17-19(25-11-24-18)29-20(28-17)27-16-14(22)5-4-6-15(16)23/h4-11H,1-3H3,(H,27,28)(H,24,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL					Assay Description Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium flux				Bioorg Med Chem Lett 19: 40-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.024 BindingDB Entry DOI: 10.7270/Q28052G3
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50253983 (CHEMBL462688 | N2-(2,6-dichlorophenyl)-5-(pyrrolid...) Show SMILES FC(F)(F)c1ccc(Nc2nc(nc3sc(Nc4c(Cl)cccc4Cl)nc23)N2CCCC2)cc1 Show InChI InChI=1S/C22H17Cl2F3N6S/c23-14-4-3-5-15(24)16(14)29-21-30-17-18(28-13-8-6-12(7-9-13)22(25,26)27)31-20(32-19(17)34-21)33-10-1-2-11-33/h3-9H,1-2,10-11H2,(H,29,30)(H,28,31,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL					Assay Description Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium flux				Bioorg Med Chem Lett 19: 40-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.024 BindingDB Entry DOI: 10.7270/Q28052G3
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM50254375 (CHEMBL467639 | N2-(2,6-dichlorophenyl)-N7-(4-(meth...) Show SMILES CSc1ccc(Nc2ncnc3sc(Nc4c(Cl)cccc4Cl)nc23)cc1 Show InChI InChI=1S/C18H13Cl2N5S2/c1-26-11-7-5-10(6-8-11)23-16-15-17(22-9-21-16)27-18(25-15)24-14-12(19)3-2-4-13(14)20/h2-9H,1H3,(H,24,25)(H,21,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL					Assay Description Antagonist activity at rat TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium flux				Bioorg Med Chem Lett 19: 40-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.024 BindingDB Entry DOI: 10.7270/Q28052G3
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50254136 (CHEMBL469297 | N2-(2,6-dichlorophenyl)-N7-(4-(trif...) Show SMILES FC(F)(F)c1ccc(Nc2ncnc3sc(Nc4c(Cl)cccc4Cl)nc23)cc1 Show InChI InChI=1S/C18H10Cl2F3N5S/c19-11-2-1-3-12(20)13(11)27-17-28-14-15(24-8-25-16(14)29-17)26-10-6-4-9(5-7-10)18(21,22)23/h1-8H,(H,27,28)(H,24,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL					Assay Description Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium flux				Bioorg Med Chem Lett 19: 40-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.024 BindingDB Entry DOI: 10.7270/Q28052G3
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50254054 (CHEMBL462276 | N2-(2,6-dichlorophenyl)-N5-isopropy...) Show SMILES CC(C)Nc1nc(Nc2ccc(cc2)C(F)(F)F)c2nc(Nc3c(Cl)cccc3Cl)sc2n1 Show InChI InChI=1S/C21H17Cl2F3N6S/c1-10(2)27-19-31-17(28-12-8-6-11(7-9-12)21(24,25)26)16-18(32-19)33-20(30-16)29-15-13(22)4-3-5-14(15)23/h3-10H,1-2H3,(H,29,30)(H2,27,28,31,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL					Assay Description Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium flux				Bioorg Med Chem Lett 19: 40-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.024 BindingDB Entry DOI: 10.7270/Q28052G3
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM50254173 (CHEMBL465986 | N2-o-tolyl-N7-(4-(trifluoromethyl)p...) Show SMILES Cc1ccccc1Nc1nc2c(Nc3ccc(cc3)C(F)(F)F)ncnc2s1 Show InChI InChI=1S/C19H14F3N5S/c1-11-4-2-3-5-14(11)26-18-27-15-16(23-10-24-17(15)28-18)25-13-8-6-12(7-9-13)19(20,21)22/h2-10H,1H3,(H,26,27)(H,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL					Assay Description Antagonist activity at rat TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium flux				Bioorg Med Chem Lett 19: 40-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.024 BindingDB Entry DOI: 10.7270/Q28052G3
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50254322 (CHEMBL467007 | N2-(2,6-dichlorophenyl)-N7-(6-(trif...) Show SMILES FC(F)(F)c1ccc(Nc2ncnc3sc(Nc4c(Cl)cccc4Cl)nc23)cn1 Show InChI InChI=1S/C17H9Cl2F3N6S/c18-9-2-1-3-10(19)12(9)27-16-28-13-14(24-7-25-15(13)29-16)26-8-4-5-11(23-6-8)17(20,21)22/h1-7H,(H,27,28)(H,24,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL					Assay Description Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium flux				Bioorg Med Chem Lett 19: 40-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.024 BindingDB Entry DOI: 10.7270/Q28052G3
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50254114 (CHEMBL461658 | N-(4-(trifluoromethyl)phenyl)-7-(3-...) Show SMILES FC(F)(F)c1ccc(Nc2ncnc3CN(CCc23)c2ncccc2C(F)(F)F)cc1 Show InChI InChI=1S/C20H15F6N5/c21-19(22,23)12-3-5-13(6-4-12)30-17-14-7-9-31(10-16(14)28-11-29-17)18-15(20(24,25)26)2-1-8-27-18/h1-6,8,11H,7,9-10H2,(H,28,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL					Assay Description Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium flux				Bioorg Med Chem Lett 19: 40-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.024 BindingDB Entry DOI: 10.7270/Q28052G3
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM50254029 (CHEMBL460146 | N2-(2,6-dichlorophenyl)-5-morpholin...) Show SMILES FC(F)(F)c1ccc(Nc2nc(nc3sc(Nc4c(Cl)cccc4Cl)nc23)N2CCOCC2)cc1 Show InChI InChI=1S/C22H17Cl2F3N6OS/c23-14-2-1-3-15(24)16(14)29-21-30-17-18(28-13-6-4-12(5-7-13)22(25,26)27)31-20(32-19(17)35-21)33-8-10-34-11-9-33/h1-7H,8-11H2,(H,29,30)(H,28,31,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL					Assay Description Antagonist activity at rat TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium flux				Bioorg Med Chem Lett 19: 40-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.024 BindingDB Entry DOI: 10.7270/Q28052G3
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50254136 (CHEMBL469297 | N2-(2,6-dichlorophenyl)-N7-(4-(trif...) Show SMILES FC(F)(F)c1ccc(Nc2ncnc3sc(Nc4c(Cl)cccc4Cl)nc23)cc1 Show InChI InChI=1S/C18H10Cl2F3N5S/c19-11-2-1-3-12(20)13(11)27-17-28-14-15(24-8-25-16(14)29-17)26-10-6-4-9(5-7-10)18(21,22)23/h1-8H,(H,27,28)(H,24,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL					Assay Description Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as inhibition of low pH-induced calcium influx				Bioorg Med Chem Lett 19: 40-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.024 BindingDB Entry DOI: 10.7270/Q28052G3
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50254420 (CHEMBL517044 | N7-(3-chloro-4-(trifluoromethyl)phe...) Show SMILES FC(F)(F)c1ccc(Nc2ncnc3sc(Nc4c(Cl)cccc4Cl)nc23)cc1Cl Show InChI InChI=1S/C18H9Cl3F3N5S/c19-10-2-1-3-11(20)13(10)28-17-29-14-15(25-7-26-16(14)30-17)27-8-4-5-9(12(21)6-8)18(22,23)24/h1-7H,(H,28,29)(H,25,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL					Assay Description Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium flux				Bioorg Med Chem Lett 19: 40-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.024 BindingDB Entry DOI: 10.7270/Q28052G3
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50254153 (CHEMBL511589 | N2-(2,6-dimethylphenyl)-N7-(4-(trif...) Show SMILES Cc1cccc(C)c1Nc1nc2c(Nc3ccc(cc3)C(F)(F)F)ncnc2s1 Show InChI InChI=1S/C20H16F3N5S/c1-11-4-3-5-12(2)15(11)27-19-28-16-17(24-10-25-18(16)29-19)26-14-8-6-13(7-9-14)20(21,22)23/h3-10H,1-2H3,(H,27,28)(H,24,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL					Assay Description Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium flux				Bioorg Med Chem Lett 19: 40-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.024 BindingDB Entry DOI: 10.7270/Q28052G3
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM50253964 (5-(azetidin-1-yl)-N2-(2,6-dichlorophenyl)-N7-(4-(t...) Show SMILES FC(F)(F)c1ccc(Nc2nc(nc3sc(Nc4c(Cl)cccc4Cl)nc23)N2CCC2)cc1 Show InChI InChI=1S/C21H15Cl2F3N6S/c22-13-3-1-4-14(23)15(13)28-20-29-16-17(27-12-7-5-11(6-8-12)21(24,25)26)30-19(31-18(16)33-20)32-9-2-10-32/h1,3-8H,2,9-10H2,(H,28,29)(H,27,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL					Assay Description Antagonist activity at rat TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium flux				Bioorg Med Chem Lett 19: 40-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.024 BindingDB Entry DOI: 10.7270/Q28052G3
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM50254156 (CHEMBL467634 | N2-(2-(methylthio)phenyl)-N7-(4-(tr...) Show SMILES CSc1ccccc1Nc1nc2c(Nc3ccc(cc3)C(F)(F)F)ncnc2s1 Show InChI InChI=1S/C19H14F3N5S2/c1-28-14-5-3-2-4-13(14)26-18-27-15-16(23-10-24-17(15)29-18)25-12-8-6-11(7-9-12)19(20,21)22/h2-10H,1H3,(H,26,27)(H,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL					Assay Description Antagonist activity at rat TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium flux				Bioorg Med Chem Lett 19: 40-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.024 BindingDB Entry DOI: 10.7270/Q28052G3
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50254029 (CHEMBL460146 | N2-(2,6-dichlorophenyl)-5-morpholin...) Show SMILES FC(F)(F)c1ccc(Nc2nc(nc3sc(Nc4c(Cl)cccc4Cl)nc23)N2CCOCC2)cc1 Show InChI InChI=1S/C22H17Cl2F3N6OS/c23-14-2-1-3-15(24)16(14)29-21-30-17-18(28-13-6-4-12(5-7-13)22(25,26)27)31-20(32-19(17)35-21)33-8-10-34-11-9-33/h1-7H,8-11H2,(H,29,30)(H,28,31,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL					Assay Description Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium flux				Bioorg Med Chem Lett 19: 40-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.024 BindingDB Entry DOI: 10.7270/Q28052G3
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50254326 (2-(4-(2-(2,6-dichlorophenylamino)thiazolo[5,4-d]py...) Show SMILES CC(C)(C(O)=O)c1ccc(Nc2ncnc3sc(Nc4c(Cl)cccc4Cl)nc23)cc1 Show InChI InChI=1S/C21H17Cl2N5O2S/c1-21(2,19(29)30)11-6-8-12(9-7-11)26-17-16-18(25-10-24-17)31-20(28-16)27-15-13(22)4-3-5-14(15)23/h3-10H,1-2H3,(H,27,28)(H,29,30)(H,24,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL					Assay Description Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium flux				Bioorg Med Chem Lett 19: 40-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.024 BindingDB Entry DOI: 10.7270/Q28052G3
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM50254155 (CHEMBL467431 | N2-(2-chlorophenyl)-N7-(4-(trifluor...) Show SMILES FC(F)(F)c1ccc(Nc2ncnc3sc(Nc4ccccc4Cl)nc23)cc1 Show InChI InChI=1S/C18H11ClF3N5S/c19-12-3-1-2-4-13(12)26-17-27-14-15(23-9-24-16(14)28-17)25-11-7-5-10(6-8-11)18(20,21)22/h1-9H,(H,26,27)(H,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL					Assay Description Antagonist activity at rat TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium flux				Bioorg Med Chem Lett 19: 40-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.024 BindingDB Entry DOI: 10.7270/Q28052G3
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM50254323 (CHEMBL511221 | N2-(2,6-dichlorophenyl)-N7-p-tolylt...) Show SMILES Cc1ccc(Nc2ncnc3sc(Nc4c(Cl)cccc4Cl)nc23)cc1 Show InChI InChI=1S/C18H13Cl2N5S/c1-10-5-7-11(8-6-10)23-16-15-17(22-9-21-16)26-18(25-15)24-14-12(19)3-2-4-13(14)20/h2-9H,1H3,(H,24,25)(H,21,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL					Assay Description Antagonist activity at rat TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium flux				Bioorg Med Chem Lett 19: 40-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.024 BindingDB Entry DOI: 10.7270/Q28052G3
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM50254028 (CHEMBL460145 | N2-(2,6-dichlorophenyl)-5-(piperidi...) Show SMILES FC(F)(F)c1ccc(Nc2nc(nc3sc(Nc4c(Cl)cccc4Cl)nc23)N2CCCCC2)cc1 Show InChI InChI=1S/C23H19Cl2F3N6S/c24-15-5-4-6-16(25)17(15)30-22-31-18-19(29-14-9-7-13(8-10-14)23(26,27)28)32-21(33-20(18)35-22)34-11-2-1-3-12-34/h4-10H,1-3,11-12H2,(H,30,31)(H,29,32,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL					Assay Description Antagonist activity at rat TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium flux				Bioorg Med Chem Lett 19: 40-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.024 BindingDB Entry DOI: 10.7270/Q28052G3
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50254323 (CHEMBL511221 | N2-(2,6-dichlorophenyl)-N7-p-tolylt...) Show SMILES Cc1ccc(Nc2ncnc3sc(Nc4c(Cl)cccc4Cl)nc23)cc1 Show InChI InChI=1S/C18H13Cl2N5S/c1-10-5-7-11(8-6-10)23-16-15-17(22-9-21-16)26-18(25-15)24-14-12(19)3-2-4-13(14)20/h2-9H,1H3,(H,24,25)(H,21,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL					Assay Description Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium flux				Bioorg Med Chem Lett 19: 40-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.024 BindingDB Entry DOI: 10.7270/Q28052G3
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM50254052 (CHEMBL462067 | N2-(2,6-dichlorophenyl)-N5,N5-dieth...) Show SMILES CCN(CC)c1nc(Nc2ccc(cc2)C(F)(F)F)c2nc(Nc3c(Cl)cccc3Cl)sc2n1 Show InChI InChI=1S/C22H19Cl2F3N6S/c1-3-33(4-2)20-31-18(28-13-10-8-12(9-11-13)22(25,26)27)17-19(32-20)34-21(30-17)29-16-14(23)6-5-7-15(16)24/h5-11H,3-4H2,1-2H3,(H,29,30)(H,28,31,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL					Assay Description Antagonist activity at rat TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium flux				Bioorg Med Chem Lett 19: 40-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.024 BindingDB Entry DOI: 10.7270/Q28052G3
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM50253983 (CHEMBL462688 | N2-(2,6-dichlorophenyl)-5-(pyrrolid...) Show SMILES FC(F)(F)c1ccc(Nc2nc(nc3sc(Nc4c(Cl)cccc4Cl)nc23)N2CCCC2)cc1 Show InChI InChI=1S/C22H17Cl2F3N6S/c23-14-4-3-5-15(24)16(14)29-21-30-17-18(28-13-8-6-12(7-9-13)22(25,26)27)31-20(32-19(17)34-21)33-10-1-2-11-33/h3-9H,1-2,10-11H2,(H,29,30)(H,28,31,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL					Assay Description Antagonist activity at rat TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium flux				Bioorg Med Chem Lett 19: 40-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.024 BindingDB Entry DOI: 10.7270/Q28052G3
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM50254174 (CHEMBL468268 | N2-(2-(trifluoromethyl)phenyl)-N7-(...) Show SMILES FC(F)(F)c1ccc(Nc2ncnc3sc(Nc4ccccc4C(F)(F)F)nc23)cc1 Show InChI InChI=1S/C19H11F6N5S/c20-18(21,22)10-5-7-11(8-6-10)28-15-14-16(27-9-26-15)31-17(30-14)29-13-4-2-1-3-12(13)19(23,24)25/h1-9H,(H,29,30)(H,26,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL					Assay Description Antagonist activity at rat TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium flux				Bioorg Med Chem Lett 19: 40-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.024 BindingDB Entry DOI: 10.7270/Q28052G3
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50254079 (CHEMBL459320 | N2-(2,6-dichlorophenyl)-N5-(2-morph...) Show SMILES FC(F)(F)c1ccc(Nc2nc(NCCN3CCOCC3)nc3sc(Nc4c(Cl)cccc4Cl)nc23)cc1 Show InChI InChI=1S/C24H22Cl2F3N7OS/c25-16-2-1-3-17(26)18(16)32-23-33-19-20(31-15-6-4-14(5-7-15)24(27,28)29)34-22(35-21(19)38-23)30-8-9-36-10-12-37-13-11-36/h1-7H,8-13H2,(H,32,33)(H2,30,31,34,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL					Assay Description Antagonist activity at human TRPV1 expressed in HEK293 cells assessed as inhibition of capsaicin-induced calcium flux				Bioorg Med Chem Lett 19: 40-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.024 BindingDB Entry DOI: 10.7270/Q28052G3
					More data for this Ligand-Target Pair

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