Compile Data Set for Download or QSAR

Found 279 hits with Last Name = 'kingston' and Initial = 'ae'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 3 (Homo sapiens (Human))	BDBM50138784 ((1R,2S,3R)-2-((S)-Amino-carboxy-methyl)-3-hydroxy-...) Show SMILES N[C@@H]([C@H]1[C@@H](O)[C@@H]1C(O)=O)C(O)=O Show InChI InChI=1S/C6H9NO5/c7-3(6(11)12)1-2(4(1)8)5(9)10/h1-4,8H,7H2,(H,9,10)(H,11,12)/t1-,2+,3-,4+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly, SA Curated by ChEMBL					Assay Description Binding affinity of the compound towards metabotropic glutamate receptor 3 was determined				J Med Chem 47: 456-66 (2004) Article DOI: 10.1021/jm030967o BindingDB Entry DOI: 10.7270/Q2K936Z5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50138784 ((1R,2S,3R)-2-((S)-Amino-carboxy-methyl)-3-hydroxy-...) Show SMILES N[C@@H]([C@H]1[C@@H](O)[C@@H]1C(O)=O)C(O)=O Show InChI InChI=1S/C6H9NO5/c7-3(6(11)12)1-2(4(1)8)5(9)10/h1-4,8H,7H2,(H,9,10)(H,11,12)/t1-,2+,3-,4+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly, SA Curated by ChEMBL					Assay Description Binding affinity of the compound towards metabotropic glutamate receptor 2 was determined				J Med Chem 47: 456-66 (2004) Article DOI: 10.1021/jm030967o BindingDB Entry DOI: 10.7270/Q2K936Z5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 3 (Homo sapiens (Human))	BDBM50138785 ((1S,2R,3S)-2-((R)-Amino-carboxy-methyl)-3-hydroxy-...) Show SMILES N[C@H]([C@@H]1[C@H](O)[C@H]1C(O)=O)C(O)=O Show InChI InChI=1S/C6H9NO5/c7-3(6(11)12)1-2(4(1)8)5(9)10/h1-4,8H,7H2,(H,9,10)(H,11,12)/t1-,2+,3-,4+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly, SA Curated by ChEMBL					Assay Description Binding affinity of the compound towards Metabotropic glutamate receptor 3 was determined				J Med Chem 47: 456-66 (2004) Article DOI: 10.1021/jm030967o BindingDB Entry DOI: 10.7270/Q2K936Z5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50138785 ((1S,2R,3S)-2-((R)-Amino-carboxy-methyl)-3-hydroxy-...) Show SMILES N[C@H]([C@@H]1[C@H](O)[C@H]1C(O)=O)C(O)=O Show InChI InChI=1S/C6H9NO5/c7-3(6(11)12)1-2(4(1)8)5(9)10/h1-4,8H,7H2,(H,9,10)(H,11,12)/t1-,2+,3-,4+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly, SA Curated by ChEMBL					Assay Description Binding affinity of the compound towards metabotropic glutamate receptor 2 was determined				J Med Chem 47: 456-66 (2004) Article DOI: 10.1021/jm030967o BindingDB Entry DOI: 10.7270/Q2K936Z5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50163592 ((3,4-Dihydro-2H-1-oxa-9-aza-anthracen-6-yl)-(4-met...) Show SMILES CO[C@H]1CC[C@H](CC1)C(=O)c1ccc2nc3OCCCc3cc2c1 |wU:5.8,2.1,(-8.6,-.89,;-7.27,-1.66,;-5.94,-.89,;-5.94,.65,;-4.61,1.42,;-3.28,.65,;-3.28,-.89,;-4.61,-1.66,;-1.95,1.42,;-1.98,2.96,;-.62,.67,;-.62,-.87,;.72,-1.64,;2.05,-.85,;3.39,-1.62,;4.72,-.82,;6.07,-1.57,;7.4,-.8,;7.38,.76,;6.03,1.51,;4.7,.72,;3.36,1.49,;2.04,.69,;.71,1.44,)| Show InChI InChI=1S/C20H23NO3/c1-23-17-7-4-13(5-8-17)19(22)14-6-9-18-16(11-14)12-15-3-2-10-24-20(15)21-18/h6,9,11-13,17H,2-5,7-8,10H2,1H3/t13-,17+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.21	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Labs Curated by ChEMBL					Assay Description Antagonist activity at human mGlu1 receptor				J Med Chem 50: 2563-8 (2007) Article DOI: 10.1021/jm060950g BindingDB Entry DOI: 10.7270/Q2XS5W7Q
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50177053 (9-Dimethylamino-3-(4-ethyl-phenyl)-3H-pyrido[3',2'...) Show SMILES CCc1ccc(cc1)-n1cnc2c(sc3nccc(N(C)C)c23)c1=O Show InChI InChI=1S/C19H18N4OS/c1-4-12-5-7-13(8-6-12)23-11-21-16-15-14(22(2)3)9-10-20-18(15)25-17(16)19(23)24/h5-11H,4H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Labs Curated by ChEMBL					Assay Description Antagonist activity at mGlu1 receptor				J Med Chem 50: 2563-8 (2007) Article DOI: 10.1021/jm060950g BindingDB Entry DOI: 10.7270/Q2XS5W7Q
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50212328 (4-(1-(2-fluoropyridin-3-yl)-5-methyl-1H-1,2,3-tria...) Show SMILES CC(C)N(C)C(=O)C1CCC(=CC1)c1nnn(c1C)-c1cccnc1F |w:7.6,c:10| Show InChI InChI=1S/C19H24FN5O/c1-12(2)24(4)19(26)15-9-7-14(8-10-15)17-13(3)25(23-22-17)16-6-5-11-21-18(16)20/h5-7,11-12,15H,8-10H2,1-4H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Labs Curated by ChEMBL					Assay Description Antagonist activity at mGlu1 receptor				J Med Chem 50: 2563-8 (2007) Article DOI: 10.1021/jm060950g BindingDB Entry DOI: 10.7270/Q2XS5W7Q
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50212324 (6-amino-N-cyclohexyl-N,3-dimethylthiazolo[3,2-alph...) Show SMILES Cc1c(sc2nc3ccc(N)cc3n12)C(=O)NC1CCCCC1 Show InChI InChI=1S/C17H20N4OS/c1-10-15(16(22)19-12-5-3-2-4-6-12)23-17-20-13-8-7-11(18)9-14(13)21(10)17/h7-9,12H,2-6,18H2,1H3,(H,19,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Labs Curated by ChEMBL					Assay Description Antagonist activity at mGlu1 receptor				J Med Chem 50: 2563-8 (2007) Article DOI: 10.1021/jm060950g BindingDB Entry DOI: 10.7270/Q2XS5W7Q
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 3 (Rattus norvegicus (Rat))	BDBM50062522 ((1S,2S)-2-((S)-1-amino-1-carboxy-2-(9H-xanthen-9-y...) Show SMILES N[C@@](CC1c2ccccc2Oc2ccccc12)([C@H]1C[C@@H]1C(O)=O)C(O)=O Show InChI InChI=1S/C20H19NO5/c21-20(19(24)25,15-9-13(15)18(22)23)10-14-11-5-1-3-7-16(11)26-17-8-4-2-6-12(14)17/h1-8,13-15H,9-10,21H2,(H,22,23)(H,24,25)/t13-,15-,20-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Similars	PDB PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigación Lilly, SA Curated by ChEMBL					Assay Description Antagonistic activity against metabotropic glutamate receptor 3 (mGluR3) was evaluated				Bioorg Med Chem Lett 8: 2849-54 (1999) BindingDB Entry DOI: 10.7270/Q2Z0379C
					More data for this Ligand-Target Pair				3D Structure (crystal)
Metabotropic glutamate receptor 3 (Rattus norvegicus (Rat))	BDBM50072177 ((1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl...) Show SMILES CCCC[C@@H]1[C@@H]([C@H]1C(N)(CC1c2ccccc2Oc2ccccc12)C(O)=O)C(O)=O Show InChI InChI=1S/C24H27NO5/c1-2-3-8-16-20(22(26)27)21(16)24(25,23(28)29)13-17-14-9-4-6-11-18(14)30-19-12-7-5-10-15(17)19/h4-7,9-12,16-17,20-21H,2-3,8,13,25H2,1H3,(H,26,27)(H,28,29)/t16-,20+,21+,24?/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigación Lilly, SA Curated by ChEMBL					Assay Description Antagonistic activity against metabotropic glutamate receptor 3 (mGluR3) was evaluated				Bioorg Med Chem Lett 8: 2849-54 (1999) BindingDB Entry DOI: 10.7270/Q2Z0379C
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 3 (Rattus norvegicus (Rat))	BDBM50072170 ((1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl...) Show SMILES CC(C)C[C@@H]1[C@@H]([C@H]1C(N)(CC1c2ccccc2Oc2ccccc12)C(O)=O)C(O)=O Show InChI InChI=1S/C24H27NO5/c1-13(2)11-16-20(22(26)27)21(16)24(25,23(28)29)12-17-14-7-3-5-9-18(14)30-19-10-6-4-8-15(17)19/h3-10,13,16-17,20-21H,11-12,25H2,1-2H3,(H,26,27)(H,28,29)/t16-,20+,21+,24?/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigación Lilly, SA Curated by ChEMBL					Assay Description Antagonistic activity against metabotropic glutamate receptor 3 (mGluR3) was evaluated				Bioorg Med Chem Lett 8: 2849-54 (1999) BindingDB Entry DOI: 10.7270/Q2Z0379C
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 3 (Rattus norvegicus (Rat))	BDBM50072172 ((1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl...) Show SMILES CC[C@@H]1[C@@H]([C@H]1C(N)(CC1c2ccccc2Oc2ccccc12)C(O)=O)C(O)=O Show InChI InChI=1S/C22H23NO5/c1-2-12-18(20(24)25)19(12)22(23,21(26)27)11-15-13-7-3-5-9-16(13)28-17-10-6-4-8-14(15)17/h3-10,12,15,18-19H,2,11,23H2,1H3,(H,24,25)(H,26,27)/t12-,18+,19+,22?/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	76	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigación Lilly, SA Curated by ChEMBL					Assay Description Antagonistic activity against metabotropic glutamate receptor 3 (mGluR3) was evaluated				Bioorg Med Chem Lett 8: 2849-54 (1999) BindingDB Entry DOI: 10.7270/Q2Z0379C
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50212322 (4-methoxyphenyl-6-methoxyquinazolin-4-yl | CHEMBL2...) Show SMILES COc1ccc(Nc2ncnc3ccc(OC)cc23)cc1 Show InChI InChI=1S/C16H15N3O2/c1-20-12-5-3-11(4-6-12)19-16-14-9-13(21-2)7-8-15(14)17-10-18-16/h3-10H,1-2H3,(H,17,18,19)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	96	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Labs Curated by ChEMBL					Assay Description Antagonist activity at mGlu1 receptor				J Med Chem 50: 2563-8 (2007) Article DOI: 10.1021/jm060950g BindingDB Entry DOI: 10.7270/Q2XS5W7Q
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 3 (Rattus norvegicus (Rat))	BDBM50072169 ((1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl...) Show SMILES CCCCC[C@@H]1[C@@H]([C@H]1C(N)(CC1c2ccccc2Oc2ccccc12)C(O)=O)C(O)=O Show InChI InChI=1S/C25H29NO5/c1-2-3-4-11-17-21(23(27)28)22(17)25(26,24(29)30)14-18-15-9-5-7-12-19(15)31-20-13-8-6-10-16(18)20/h5-10,12-13,17-18,21-22H,2-4,11,14,26H2,1H3,(H,27,28)(H,29,30)/t17-,21+,22+,25?/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigación Lilly, SA Curated by ChEMBL					Assay Description Antagonistic activity against metabotropic glutamate receptor 3 (mGluR3) was evaluated				Bioorg Med Chem Lett 8: 2849-54 (1999) BindingDB Entry DOI: 10.7270/Q2Z0379C
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 3 (Rattus norvegicus (Rat))	BDBM50072173 ((1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl...) Show SMILES CCCCCC[C@@H]1[C@@H]([C@H]1C(N)(CC1c2ccccc2Oc2ccccc12)C(O)=O)C(O)=O Show InChI InChI=1S/C26H31NO5/c1-2-3-4-5-12-18-22(24(28)29)23(18)26(27,25(30)31)15-19-16-10-6-8-13-20(16)32-21-14-9-7-11-17(19)21/h6-11,13-14,18-19,22-23H,2-5,12,15,27H2,1H3,(H,28,29)(H,30,31)/t18-,22+,23+,26?/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	122	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigación Lilly, SA Curated by ChEMBL					Assay Description Antagonistic activity against metabotropic glutamate receptor 3 (mGluR3) was evaluated				Bioorg Med Chem Lett 8: 2849-54 (1999) BindingDB Entry DOI: 10.7270/Q2Z0379C
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 3 (Rattus norvegicus (Rat))	BDBM50072176 ((1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl...) Show SMILES NC(CC1c2ccccc2Oc2ccccc12)([C@H]1[C@H](CCc2ccccc2)[C@@H]1C(O)=O)C(O)=O Show InChI InChI=1S/C28H27NO5/c29-28(27(32)33,25-20(24(25)26(30)31)15-14-17-8-2-1-3-9-17)16-21-18-10-4-6-12-22(18)34-23-13-7-5-11-19(21)23/h1-13,20-21,24-25H,14-16,29H2,(H,30,31)(H,32,33)/t20-,24+,25+,28?/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	125	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigación Lilly, SA Curated by ChEMBL					Assay Description Antagonistic activity against metabotropic glutamate receptor 3 (mGluR3) was evaluated				Bioorg Med Chem Lett 8: 2849-54 (1999) BindingDB Entry DOI: 10.7270/Q2Z0379C
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50212323 ((3aS,6aS)-5-methylene-6a-(naphthalen-2-ylmethyl)-h...) Show SMILES C=C1C[C@@H]2COC(=O)[C@]2(Cc2ccc3ccccc3c2)C1 Show InChI InChI=1S/C19H18O2/c1-13-8-17-12-21-18(20)19(17,10-13)11-14-6-7-15-4-2-3-5-16(15)9-14/h2-7,9,17H,1,8,10-12H2/t17-,19+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Labs Curated by ChEMBL					Assay Description Antagonist activity at mGlu1 receptor				J Med Chem 50: 2563-8 (2007) Article DOI: 10.1021/jm060950g BindingDB Entry DOI: 10.7270/Q2XS5W7Q
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 8 (Homo sapiens (Human))	BDBM50062522 ((1S,2S)-2-((S)-1-amino-1-carboxy-2-(9H-xanthen-9-y...) Show SMILES N[C@@](CC1c2ccccc2Oc2ccccc12)([C@H]1C[C@@H]1C(O)=O)C(O)=O Show InChI InChI=1S/C20H19NO5/c21-20(19(24)25,15-9-13(15)18(22)23)10-14-11-5-1-3-7-16(11)26-17-8-4-2-6-12(14)17/h1-8,13-15H,9-10,21H2,(H,22,23)(H,24,25)/t13-,15-,20-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Similars	PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigación Lilly, SA Curated by ChEMBL					Assay Description Antagonistic activity against metabotropic glutamate receptor 8 (mGluR8) was evaluated				Bioorg Med Chem Lett 8: 2849-54 (1999) BindingDB Entry DOI: 10.7270/Q2Z0379C
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 3 (Rattus norvegicus (Rat))	BDBM50072168 ((1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl...) Show SMILES CCC[C@@H]1[C@@H]([C@H]1C(N)(CC1c2ccccc2Oc2ccccc12)C(O)=O)C(O)=O Show InChI InChI=1S/C23H25NO5/c1-2-7-15-19(21(25)26)20(15)23(24,22(27)28)12-16-13-8-3-5-10-17(13)29-18-11-6-4-9-14(16)18/h3-6,8-11,15-16,19-20H,2,7,12,24H2,1H3,(H,25,26)(H,27,28)/t15-,19+,20+,23?/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	196	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigación Lilly, SA Curated by ChEMBL					Assay Description Antagonistic activity against metabotropic glutamate receptor 3 (mGluR3) was evaluated				Bioorg Med Chem Lett 8: 2849-54 (1999) BindingDB Entry DOI: 10.7270/Q2Z0379C
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Rattus norvegicus)	BDBM50062522 ((1S,2S)-2-((S)-1-amino-1-carboxy-2-(9H-xanthen-9-y...) Show SMILES N[C@@](CC1c2ccccc2Oc2ccccc12)([C@H]1C[C@@H]1C(O)=O)C(O)=O Show InChI InChI=1S/C20H19NO5/c21-20(19(24)25,15-9-13(15)18(22)23)10-14-11-5-1-3-7-16(11)26-17-8-4-2-6-12(14)17/h1-8,13-15H,9-10,21H2,(H,22,23)(H,24,25)/t13-,15-,20-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Similars	PDB PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigación Lilly, SA Curated by ChEMBL					Assay Description Antagonistic activity against metabotropic glutamate receptor 2 (mGluR2) was evaluated				Bioorg Med Chem Lett 8: 2849-54 (1999) BindingDB Entry DOI: 10.7270/Q2Z0379C
					More data for this Ligand-Target Pair				3D Structure (crystal)
Metabotropic glutamate receptor 8 (Homo sapiens (Human))	BDBM50072169 ((1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl...) Show SMILES CCCCC[C@@H]1[C@@H]([C@H]1C(N)(CC1c2ccccc2Oc2ccccc12)C(O)=O)C(O)=O Show InChI InChI=1S/C25H29NO5/c1-2-3-4-11-17-21(23(27)28)22(17)25(26,24(29)30)14-18-15-9-5-7-12-19(15)31-20-13-8-6-10-16(18)20/h5-10,12-13,17-18,21-22H,2-4,11,14,26H2,1H3,(H,27,28)(H,29,30)/t17-,21+,22+,25?/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigación Lilly, SA Curated by ChEMBL					Assay Description Antagonistic activity against metabotropic glutamate receptor 8 (mGluR8) was evaluated				Bioorg Med Chem Lett 8: 2849-54 (1999) BindingDB Entry DOI: 10.7270/Q2Z0379C
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 8 (Homo sapiens (Human))	BDBM50072170 ((1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl...) Show SMILES CC(C)C[C@@H]1[C@@H]([C@H]1C(N)(CC1c2ccccc2Oc2ccccc12)C(O)=O)C(O)=O Show InChI InChI=1S/C24H27NO5/c1-13(2)11-16-20(22(26)27)21(16)24(25,23(28)29)12-17-14-7-3-5-9-18(14)30-19-10-6-4-8-15(17)19/h3-10,13,16-17,20-21H,11-12,25H2,1-2H3,(H,26,27)(H,28,29)/t16-,20+,21+,24?/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	380	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigación Lilly, SA Curated by ChEMBL					Assay Description Antagonistic activity against metabotropic glutamate receptor 8 (mGluR8) was evaluated				Bioorg Med Chem Lett 8: 2849-54 (1999) BindingDB Entry DOI: 10.7270/Q2Z0379C
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 8 (Homo sapiens (Human))	BDBM50072177 ((1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl...) Show SMILES CCCC[C@@H]1[C@@H]([C@H]1C(N)(CC1c2ccccc2Oc2ccccc12)C(O)=O)C(O)=O Show InChI InChI=1S/C24H27NO5/c1-2-3-8-16-20(22(26)27)21(16)24(25,23(28)29)13-17-14-9-4-6-11-18(14)30-19-12-7-5-10-15(17)19/h4-7,9-12,16-17,20-21H,2-3,8,13,25H2,1H3,(H,26,27)(H,28,29)/t16-,20+,21+,24?/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	490	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigación Lilly, SA Curated by ChEMBL					Assay Description Antagonistic activity against metabotropic glutamate receptor 8 (mGluR8) was evaluated				Bioorg Med Chem Lett 8: 2849-54 (1999) BindingDB Entry DOI: 10.7270/Q2Z0379C
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 8 (Homo sapiens (Human))	BDBM50072173 ((1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl...) Show SMILES CCCCCC[C@@H]1[C@@H]([C@H]1C(N)(CC1c2ccccc2Oc2ccccc12)C(O)=O)C(O)=O Show InChI InChI=1S/C26H31NO5/c1-2-3-4-5-12-18-22(24(28)29)23(18)26(27,25(30)31)15-19-16-10-6-8-13-20(16)32-21-14-9-7-11-17(19)21/h6-11,13-14,18-19,22-23H,2-5,12,15,27H2,1H3,(H,28,29)(H,30,31)/t18-,22+,23+,26?/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	750	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigación Lilly, SA Curated by ChEMBL					Assay Description Antagonistic activity against metabotropic glutamate receptor 8 (mGluR8) was evaluated				Bioorg Med Chem Lett 8: 2849-54 (1999) BindingDB Entry DOI: 10.7270/Q2Z0379C
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 8 (Homo sapiens (Human))	BDBM50072176 ((1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl...) Show SMILES NC(CC1c2ccccc2Oc2ccccc12)([C@H]1[C@H](CCc2ccccc2)[C@@H]1C(O)=O)C(O)=O Show InChI InChI=1S/C28H27NO5/c29-28(27(32)33,25-20(24(25)26(30)31)15-14-17-8-2-1-3-9-17)16-21-18-10-4-6-12-22(18)34-23-13-7-5-11-19(21)23/h1-13,20-21,24-25H,14-16,29H2,(H,30,31)(H,32,33)/t20-,24+,25+,28?/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	990	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigación Lilly, SA Curated by ChEMBL					Assay Description Antagonistic activity against metabotropic glutamate receptor 8 (mGluR8) was evaluated				Bioorg Med Chem Lett 8: 2849-54 (1999) BindingDB Entry DOI: 10.7270/Q2Z0379C
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Homo sapiens (Human))	BDBM50062522 ((1S,2S)-2-((S)-1-amino-1-carboxy-2-(9H-xanthen-9-y...) Show SMILES N[C@@](CC1c2ccccc2Oc2ccccc12)([C@H]1C[C@@H]1C(O)=O)C(O)=O Show InChI InChI=1S/C20H19NO5/c21-20(19(24)25,15-9-13(15)18(22)23)10-14-11-5-1-3-7-16(11)26-17-8-4-2-6-12(14)17/h1-8,13-15H,9-10,21H2,(H,22,23)(H,24,25)/t13-,15-,20-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Similars	PDB PubMed	n/a	n/a	990	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigación Lilly, SA Curated by ChEMBL					Assay Description Antagonistic activity against metabotropic glutamate receptor 7 (mGluR7) was evaluated				Bioorg Med Chem Lett 8: 2849-54 (1999) BindingDB Entry DOI: 10.7270/Q2Z0379C
					More data for this Ligand-Target Pair				3D Structure (crystal)
Metabotropic glutamate receptor 3 (Rattus norvegicus (Rat))	BDBM50072171 ((1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl...) Show SMILES C[C@@H]1[C@@H]([C@H]1C(N)(CC1c2ccccc2Oc2ccccc12)C(O)=O)C(O)=O Show InChI InChI=1S/C21H21NO5/c1-11-17(19(23)24)18(11)21(22,20(25)26)10-14-12-6-2-4-8-15(12)27-16-9-5-3-7-13(14)16/h2-9,11,14,17-18H,10,22H2,1H3,(H,23,24)(H,25,26)/t11-,17+,18+,21?/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigación Lilly, SA Curated by ChEMBL					Assay Description Antagonistic activity against metabotropic glutamate receptor 3 (mGluR3) was evaluated				Bioorg Med Chem Lett 8: 2849-54 (1999) BindingDB Entry DOI: 10.7270/Q2Z0379C
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50212327 (3-(amino(carboxy)(9H-thioxanthen-9-yl)methyl)cyclo...) Show SMILES NC(C1CC(C1)C(O)=O)(C1c2ccccc2Sc2ccccc12)C(O)=O |w:1.0,(-.99,1.85,;.35,1.08,;1.11,2.41,;2.59,2.84,;2.17,4.34,;.71,3.93,;2.92,5.68,;4.45,5.7,;2.13,7,;1.68,.31,;1.7,-1.23,;.37,-2,;.37,-3.54,;1.7,-4.31,;3.04,-3.54,;3.04,-1.99,;4.36,-1.22,;4.36,.32,;5.69,1.09,;5.68,2.63,;4.34,3.4,;3.02,2.62,;3.02,1.09,;-.99,.32,;-2.31,1.09,;-1,-1.22,)| Show InChI InChI=1S/C20H19NO4S/c21-20(19(24)25,12-9-11(10-12)18(22)23)17-13-5-1-3-7-15(13)26-16-8-4-2-6-14(16)17/h1-8,11-12,17H,9-10,21H2,(H,22,23)(H,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Labs Curated by ChEMBL					Assay Description Antagonist activity at mGlu1 receptor				J Med Chem 50: 2563-8 (2007) Article DOI: 10.1021/jm060950g BindingDB Entry DOI: 10.7270/Q2XS5W7Q
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 3 (Rattus norvegicus (Rat))	BDBM50072174 ((1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl...) Show SMILES CCCCCCCCC[C@@H]1[C@@H]([C@H]1C(N)(CC1c2ccccc2Oc2ccccc12)C(O)=O)C(O)=O Show InChI InChI=1S/C29H37NO5/c1-2-3-4-5-6-7-8-15-21-25(27(31)32)26(21)29(30,28(33)34)18-22-19-13-9-11-16-23(19)35-24-17-12-10-14-20(22)24/h9-14,16-17,21-22,25-26H,2-8,15,18,30H2,1H3,(H,31,32)(H,33,34)/t21-,25+,26+,29?/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigación Lilly, SA Curated by ChEMBL					Assay Description Antagonistic activity against metabotropic glutamate receptor 3 (mGluR3) was evaluated				Bioorg Med Chem Lett 8: 2849-54 (1999) BindingDB Entry DOI: 10.7270/Q2Z0379C
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 8 (Homo sapiens (Human))	BDBM50072171 ((1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl...) Show SMILES C[C@@H]1[C@@H]([C@H]1C(N)(CC1c2ccccc2Oc2ccccc12)C(O)=O)C(O)=O Show InChI InChI=1S/C21H21NO5/c1-11-17(19(23)24)18(11)21(22,20(25)26)10-14-12-6-2-4-8-15(12)27-16-9-5-3-7-13(14)16/h2-9,11,14,17-18H,10,22H2,1H3,(H,23,24)(H,25,26)/t11-,17+,18+,21?/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.23E+3	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigación Lilly, SA Curated by ChEMBL					Assay Description Antagonistic activity against metabotropic glutamate receptor 8 (mGluR8) was evaluated				Bioorg Med Chem Lett 8: 2849-54 (1999) BindingDB Entry DOI: 10.7270/Q2Z0379C
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Rattus norvegicus)	BDBM50072177 ((1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl...) Show SMILES CCCC[C@@H]1[C@@H]([C@H]1C(N)(CC1c2ccccc2Oc2ccccc12)C(O)=O)C(O)=O Show InChI InChI=1S/C24H27NO5/c1-2-3-8-16-20(22(26)27)21(16)24(25,23(28)29)13-17-14-9-4-6-11-18(14)30-19-12-7-5-10-15(17)19/h4-7,9-12,16-17,20-21H,2-3,8,13,25H2,1H3,(H,26,27)(H,28,29)/t16-,20+,21+,24?/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.32E+3	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigación Lilly, SA Curated by ChEMBL					Assay Description Antagonistic activity against metabotropic glutamate receptor 2 (mGluR2) was evaluated				Bioorg Med Chem Lett 8: 2849-54 (1999) BindingDB Entry DOI: 10.7270/Q2Z0379C
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Rattus norvegicus)	BDBM50072170 ((1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl...) Show SMILES CC(C)C[C@@H]1[C@@H]([C@H]1C(N)(CC1c2ccccc2Oc2ccccc12)C(O)=O)C(O)=O Show InChI InChI=1S/C24H27NO5/c1-13(2)11-16-20(22(26)27)21(16)24(25,23(28)29)12-17-14-7-3-5-9-18(14)30-19-10-6-4-8-15(17)19/h3-10,13,16-17,20-21H,11-12,25H2,1-2H3,(H,26,27)(H,28,29)/t16-,20+,21+,24?/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.37E+3	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigación Lilly, SA Curated by ChEMBL					Assay Description Antagonistic activity against metabotropic glutamate receptor 2 (mGluR2) was evaluated				Bioorg Med Chem Lett 8: 2849-54 (1999) BindingDB Entry DOI: 10.7270/Q2Z0379C
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Rattus norvegicus)	BDBM50072176 ((1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl...) Show SMILES NC(CC1c2ccccc2Oc2ccccc12)([C@H]1[C@H](CCc2ccccc2)[C@@H]1C(O)=O)C(O)=O Show InChI InChI=1S/C28H27NO5/c29-28(27(32)33,25-20(24(25)26(30)31)15-14-17-8-2-1-3-9-17)16-21-18-10-4-6-12-22(18)34-23-13-7-5-11-19(21)23/h1-13,20-21,24-25H,14-16,29H2,(H,30,31)(H,32,33)/t20-,24+,25+,28?/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.67E+3	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigación Lilly, SA Curated by ChEMBL					Assay Description Antagonistic activity against metabotropic glutamate receptor 2 (mGluR2) was evaluated				Bioorg Med Chem Lett 8: 2849-54 (1999) BindingDB Entry DOI: 10.7270/Q2Z0379C
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Rattus norvegicus)	BDBM50072173 ((1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl...) Show SMILES CCCCCC[C@@H]1[C@@H]([C@H]1C(N)(CC1c2ccccc2Oc2ccccc12)C(O)=O)C(O)=O Show InChI InChI=1S/C26H31NO5/c1-2-3-4-5-12-18-22(24(28)29)23(18)26(27,25(30)31)15-19-16-10-6-8-13-20(16)32-21-14-9-7-11-17(19)21/h6-11,13-14,18-19,22-23H,2-5,12,15,27H2,1H3,(H,28,29)(H,30,31)/t18-,22+,23+,26?/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.87E+3	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigación Lilly, SA Curated by ChEMBL					Assay Description Antagonistic activity against metabotropic glutamate receptor 2 (mGluR2) was evaluated				Bioorg Med Chem Lett 8: 2849-54 (1999) BindingDB Entry DOI: 10.7270/Q2Z0379C
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Rattus norvegicus)	BDBM50072174 ((1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl...) Show SMILES CCCCCCCCC[C@@H]1[C@@H]([C@H]1C(N)(CC1c2ccccc2Oc2ccccc12)C(O)=O)C(O)=O Show InChI InChI=1S/C29H37NO5/c1-2-3-4-5-6-7-8-15-21-25(27(31)32)26(21)29(30,28(33)34)18-22-19-13-9-11-16-23(19)35-24-17-12-10-14-20(22)24/h9-14,16-17,21-22,25-26H,2-8,15,18,30H2,1H3,(H,31,32)(H,33,34)/t21-,25+,26+,29?/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.16E+3	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigación Lilly, SA Curated by ChEMBL					Assay Description Antagonistic activity against metabotropic glutamate receptor 2 (mGluR2) was evaluated				Bioorg Med Chem Lett 8: 2849-54 (1999) BindingDB Entry DOI: 10.7270/Q2Z0379C
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 8 (Homo sapiens (Human))	BDBM50072168 ((1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl...) Show SMILES CCC[C@@H]1[C@@H]([C@H]1C(N)(CC1c2ccccc2Oc2ccccc12)C(O)=O)C(O)=O Show InChI InChI=1S/C23H25NO5/c1-2-7-15-19(21(25)26)20(15)23(24,22(27)28)12-16-13-8-3-5-10-17(13)29-18-11-6-4-9-14(16)18/h3-6,8-11,15-16,19-20H,2,7,12,24H2,1H3,(H,25,26)(H,27,28)/t15-,19+,20+,23?/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.25E+3	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigación Lilly, SA Curated by ChEMBL					Assay Description Antagonistic activity against metabotropic glutamate receptor 8 (mGluR8) was evaluated				Bioorg Med Chem Lett 8: 2849-54 (1999) BindingDB Entry DOI: 10.7270/Q2Z0379C
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 8 (Homo sapiens (Human))	BDBM50072172 ((1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl...) Show SMILES CC[C@@H]1[C@@H]([C@H]1C(N)(CC1c2ccccc2Oc2ccccc12)C(O)=O)C(O)=O Show InChI InChI=1S/C22H23NO5/c1-2-12-18(20(24)25)19(12)22(23,21(26)27)11-15-13-7-3-5-9-16(13)28-17-10-6-4-8-14(15)17/h3-10,12,15,18-19H,2,11,23H2,1H3,(H,24,25)(H,26,27)/t12-,18+,19+,22?/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.52E+3	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigación Lilly, SA Curated by ChEMBL					Assay Description Antagonistic activity against metabotropic glutamate receptor 8 (mGluR8) was evaluated				Bioorg Med Chem Lett 8: 2849-54 (1999) BindingDB Entry DOI: 10.7270/Q2Z0379C
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Homo sapiens (Human))	BDBM50072170 ((1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl...) Show SMILES CC(C)C[C@@H]1[C@@H]([C@H]1C(N)(CC1c2ccccc2Oc2ccccc12)C(O)=O)C(O)=O Show InChI InChI=1S/C24H27NO5/c1-13(2)11-16-20(22(26)27)21(16)24(25,23(28)29)12-17-14-7-3-5-9-18(14)30-19-10-6-4-8-15(17)19/h3-10,13,16-17,20-21H,11-12,25H2,1-2H3,(H,26,27)(H,28,29)/t16-,20+,21+,24?/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigación Lilly, SA Curated by ChEMBL					Assay Description Antagonistic activity against metabotropic glutamate receptor 7 (mGluR7) was evaluated				Bioorg Med Chem Lett 8: 2849-54 (1999) BindingDB Entry DOI: 10.7270/Q2Z0379C
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Rattus norvegicus)	BDBM50072172 ((1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl...) Show SMILES CC[C@@H]1[C@@H]([C@H]1C(N)(CC1c2ccccc2Oc2ccccc12)C(O)=O)C(O)=O Show InChI InChI=1S/C22H23NO5/c1-2-12-18(20(24)25)19(12)22(23,21(26)27)11-15-13-7-3-5-9-16(13)28-17-10-6-4-8-14(15)17/h3-10,12,15,18-19H,2,11,23H2,1H3,(H,24,25)(H,26,27)/t12-,18+,19+,22?/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.85E+3	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigación Lilly, SA Curated by ChEMBL					Assay Description Antagonistic activity against metabotropic glutamate receptor 2 (mGluR2) was evaluated				Bioorg Med Chem Lett 8: 2849-54 (1999) BindingDB Entry DOI: 10.7270/Q2Z0379C
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50212325 ((S)-(ALPHA)-METHYL-4-CARBOXYPHENYLGLYCINE | (S)-4-...) Show SMILES C[C@@](N)(C(O)=O)c1ccc(cc1)C(O)=O Show InChI InChI=1S/C10H11NO4/c1-10(11,9(14)15)7-4-2-6(3-5-7)8(12)13/h2-5H,11H2,1H3,(H,12,13)(H,14,15)/t10-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	4.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Labs Curated by ChEMBL					Assay Description Antagonist activity at mGlu1 receptor				J Med Chem 50: 2563-8 (2007) Article DOI: 10.1021/jm060950g BindingDB Entry DOI: 10.7270/Q2XS5W7Q
					More data for this Ligand-Target Pair				3D Structure (crystal)
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50212325 ((S)-(ALPHA)-METHYL-4-CARBOXYPHENYLGLYCINE | (S)-4-...) Show SMILES C[C@@](N)(C(O)=O)c1ccc(cc1)C(O)=O Show InChI InChI=1S/C10H11NO4/c1-10(11,9(14)15)7-4-2-6(3-5-7)8(12)13/h2-5H,11H2,1H3,(H,12,13)(H,14,15)/t10-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	4.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Labs Curated by ChEMBL					Assay Description Antagonist activity at mGlu2 receptor				J Med Chem 50: 2563-8 (2007) Article DOI: 10.1021/jm060950g BindingDB Entry DOI: 10.7270/Q2XS5W7Q
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 8 (Homo sapiens (Human))	BDBM50072174 ((1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl...) Show SMILES CCCCCCCCC[C@@H]1[C@@H]([C@H]1C(N)(CC1c2ccccc2Oc2ccccc12)C(O)=O)C(O)=O Show InChI InChI=1S/C29H37NO5/c1-2-3-4-5-6-7-8-15-21-25(27(31)32)26(21)29(30,28(33)34)18-22-19-13-9-11-16-23(19)35-24-17-12-10-14-20(22)24/h9-14,16-17,21-22,25-26H,2-8,15,18,30H2,1H3,(H,31,32)(H,33,34)/t21-,25+,26+,29?/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.18E+3	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigación Lilly, SA Curated by ChEMBL					Assay Description Antagonistic activity against metabotropic glutamate receptor 8 (mGluR8) was evaluated				Bioorg Med Chem Lett 8: 2849-54 (1999) BindingDB Entry DOI: 10.7270/Q2Z0379C
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50072174 ((1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl...) Show SMILES CCCCCCCCC[C@@H]1[C@@H]([C@H]1C(N)(CC1c2ccccc2Oc2ccccc12)C(O)=O)C(O)=O Show InChI InChI=1S/C29H37NO5/c1-2-3-4-5-6-7-8-15-21-25(27(31)32)26(21)29(30,28(33)34)18-22-19-13-9-11-16-23(19)35-24-17-12-10-14-20(22)24/h9-14,16-17,21-22,25-26H,2-8,15,18,30H2,1H3,(H,31,32)(H,33,34)/t21-,25+,26+,29?/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigación Lilly, SA Curated by ChEMBL					Assay Description Antagonistic activity against metabotropic glutamate receptor 5 (mGluR5) was evaluated				Bioorg Med Chem Lett 8: 2849-54 (1999) BindingDB Entry DOI: 10.7270/Q2Z0379C
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50072174 ((1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl...) Show SMILES CCCCCCCCC[C@@H]1[C@@H]([C@H]1C(N)(CC1c2ccccc2Oc2ccccc12)C(O)=O)C(O)=O Show InChI InChI=1S/C29H37NO5/c1-2-3-4-5-6-7-8-15-21-25(27(31)32)26(21)29(30,28(33)34)18-22-19-13-9-11-16-23(19)35-24-17-12-10-14-20(22)24/h9-14,16-17,21-22,25-26H,2-8,15,18,30H2,1H3,(H,31,32)(H,33,34)/t21-,25+,26+,29?/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigación Lilly, SA Curated by ChEMBL					Assay Description Antagonistic activity against metabotropic glutamate receptor 1 (mGluR1) was evaluated				Bioorg Med Chem Lett 8: 2849-54 (1999) BindingDB Entry DOI: 10.7270/Q2Z0379C
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50089913 (4-(Amino-carboxy-methyl)-2-hydroxy-3-methyl-benzoi...) Show SMILES Cc1c(O)c(ccc1C(N)C(O)=O)C(O)=O Show InChI InChI=1S/C10H11NO5/c1-4-5(7(11)10(15)16)2-3-6(8(4)12)9(13)14/h2-3,7,12H,11H2,1H3,(H,13,14)(H,15,16)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested for functional response of human metabotropic glutamate receptor mGluR1-alpha expressed in AV-12 cells by measuring inhibitory co...				Bioorg Med Chem Lett 7: 2777-2780 (1997) Article DOI: 10.1016/S0960-894X(97)10071-3 BindingDB Entry DOI: 10.7270/Q25Q4W4G
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Homo sapiens (Human))	BDBM50072173 ((1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl...) Show SMILES CCCCCC[C@@H]1[C@@H]([C@H]1C(N)(CC1c2ccccc2Oc2ccccc12)C(O)=O)C(O)=O Show InChI InChI=1S/C26H31NO5/c1-2-3-4-5-12-18-22(24(28)29)23(18)26(27,25(30)31)15-19-16-10-6-8-13-20(16)32-21-14-9-7-11-17(19)21/h6-11,13-14,18-19,22-23H,2-5,12,15,27H2,1H3,(H,28,29)(H,30,31)/t18-,22+,23+,26?/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.25E+3	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigación Lilly, SA Curated by ChEMBL					Assay Description Antagonistic activity against metabotropic glutamate receptor 7 (mGluR7) was evaluated				Bioorg Med Chem Lett 8: 2849-54 (1999) BindingDB Entry DOI: 10.7270/Q2Z0379C
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM86213 (CAS_5126051 | CHEMBL327783 | CPCCOEt | NSC_5126051) Show SMILES CCOC(=O)C12CC1C(N=O)c1ccccc1O2 Show InChI InChI=1S/C13H13NO4/c1-2-17-12(15)13-7-9(13)11(14-16)8-5-3-4-6-10(8)18-13/h3-6,9,11H,2,7H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Labs Curated by ChEMBL					Assay Description Antagonist activity at human mGlu1b receptor				J Med Chem 50: 2563-8 (2007) Article DOI: 10.1021/jm060950g BindingDB Entry DOI: 10.7270/Q2XS5W7Q
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Homo sapiens (Human))	BDBM50072169 ((1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl...) Show SMILES CCCCC[C@@H]1[C@@H]([C@H]1C(N)(CC1c2ccccc2Oc2ccccc12)C(O)=O)C(O)=O Show InChI InChI=1S/C25H29NO5/c1-2-3-4-11-17-21(23(27)28)22(17)25(26,24(29)30)14-18-15-9-5-7-12-19(15)31-20-13-8-6-10-16(18)20/h5-10,12-13,17-18,21-22H,2-4,11,14,26H2,1H3,(H,27,28)(H,29,30)/t17-,21+,22+,25?/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	7.61E+3	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigación Lilly, SA Curated by ChEMBL					Assay Description Antagonistic activity against metabotropic glutamate receptor 7 (mGluR7) was evaluated				Bioorg Med Chem Lett 8: 2849-54 (1999) BindingDB Entry DOI: 10.7270/Q2Z0379C
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50062522 ((1S,2S)-2-((S)-1-amino-1-carboxy-2-(9H-xanthen-9-y...) Show SMILES N[C@@](CC1c2ccccc2Oc2ccccc12)([C@H]1C[C@@H]1C(O)=O)C(O)=O Show InChI InChI=1S/C20H19NO5/c21-20(19(24)25,15-9-13(15)18(22)23)10-14-11-5-1-3-7-16(11)26-17-8-4-2-6-12(14)17/h1-8,13-15H,9-10,21H2,(H,22,23)(H,24,25)/t13-,15-,20-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Similars	PDB PubMed	n/a	n/a	7.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigación Lilly, SA Curated by ChEMBL					Assay Description Antagonistic activity against metabotropic glutamate receptor 1 (mGluR1) was evaluated				Bioorg Med Chem Lett 8: 2849-54 (1999) BindingDB Entry DOI: 10.7270/Q2Z0379C
					More data for this Ligand-Target Pair				3D Structure (crystal)
Metabotropic glutamate receptor 7 (Homo sapiens (Human))	BDBM50072174 ((1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl...) Show SMILES CCCCCCCCC[C@@H]1[C@@H]([C@H]1C(N)(CC1c2ccccc2Oc2ccccc12)C(O)=O)C(O)=O Show InChI InChI=1S/C29H37NO5/c1-2-3-4-5-6-7-8-15-21-25(27(31)32)26(21)29(30,28(33)34)18-22-19-13-9-11-16-23(19)35-24-17-12-10-14-20(22)24/h9-14,16-17,21-22,25-26H,2-8,15,18,30H2,1H3,(H,31,32)(H,33,34)/t21-,25+,26+,29?/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	7.82E+3	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigación Lilly, SA Curated by ChEMBL					Assay Description Antagonistic activity against metabotropic glutamate receptor 7 (mGluR7) was evaluated				Bioorg Med Chem Lett 8: 2849-54 (1999) BindingDB Entry DOI: 10.7270/Q2Z0379C
					More data for this Ligand-Target Pair

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