Compile Data Set for Download or QSAR

Found 284 hits with Last Name = 'nagasue' and Initial = 'h'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor IX (Rattus norvegicus)	BDBM50240469 (CHEMBL4096341) Show SMILES [H][C@@]12CC[C@]([H])([C@H]1NC(=O)c1ccc(cc1Cl)-n1cnc(C)n1)N(C2)c1ncc(Cl)c2cnoc12 |r,TLB:7:6:23.24:2.3,THB:25:23:6:2.3| Show InChI InChI=1S/C22H19Cl2N7O2/c1-11-26-10-31(29-11)13-3-4-14(16(23)6-13)22(32)28-19-12-2-5-18(19)30(9-12)21-20-15(7-27-33-20)17(24)8-25-21/h3-4,6-8,10,12,18-19H,2,5,9H2,1H3,(H,28,32)/t12-,18+,19-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.70	n/a	n/a	n/a	n/a	n/a	n/a
Mochida Pharmaceutical Co. Ltd. Curated by ChEMBL					Assay Description Inhibition of rat coagulation factor 9a				Bioorg Med Chem Lett 27: 2622-2628 (2017) Article DOI: 10.1016/j.bmcl.2017.03.002 BindingDB Entry DOI: 10.7270/Q28054RH
					More data for this Ligand-Target Pair
Coagulation factor IX (Homo sapiens (Human))	BDBM50240469 (CHEMBL4096341) Show SMILES [H][C@@]12CC[C@]([H])([C@H]1NC(=O)c1ccc(cc1Cl)-n1cnc(C)n1)N(C2)c1ncc(Cl)c2cnoc12 |r,TLB:7:6:23.24:2.3,THB:25:23:6:2.3| Show InChI InChI=1S/C22H19Cl2N7O2/c1-11-26-10-31(29-11)13-3-4-14(16(23)6-13)22(32)28-19-12-2-5-18(19)30(9-12)21-20-15(7-27-33-20)17(24)8-25-21/h3-4,6-8,10,12,18-19H,2,5,9H2,1H3,(H,28,32)/t12-,18+,19-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.90	n/a	n/a	n/a	n/a	n/a	n/a
Mochida Pharmaceutical Co. Ltd. Curated by ChEMBL					Assay Description Inhibition of human coagulation factor 9a using SPECTROFLUOR F9a as substrate after 60 mins by fluorescence assay				Bioorg Med Chem Lett 27: 2622-2628 (2017) Article DOI: 10.1016/j.bmcl.2017.03.002 BindingDB Entry DOI: 10.7270/Q28054RH
					More data for this Ligand-Target Pair
Coagulation factor IX (Homo sapiens (Human))	BDBM50240470 (CHEMBL4092982 | US9969724, Example 27) Show SMILES Nc1noc2c(ncc(Cl)c12)N1CC[C@H](C1)NC(=O)c1ccc(cc1Cl)-n1cnc(CCO)c1 |r| Show InChI InChI=1S/C22H21Cl2N7O3/c23-16-7-14(31-9-12(4-6-32)27-11-31)1-2-15(16)22(33)28-13-3-5-30(10-13)21-19-18(17(24)8-26-21)20(25)29-34-19/h1-2,7-9,11,13,32H,3-6,10H2,(H2,25,29)(H,28,33)/t13-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Mochida Pharmaceutical Co. Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against human plasma renin at pH 7.4				Bioorg Med Chem Lett 27: 2622-2628 (2017) Article DOI: 10.1016/j.bmcl.2017.03.002 BindingDB Entry DOI: 10.7270/Q28054RH
					More data for this Ligand-Target Pair
Coagulation factor IX (Homo sapiens (Human))	BDBM50240487 (CHEMBL4066380 | US9969724, Example 32) Show SMILES Nc1noc2c(ncc(Cl)c12)N1CC[C@H](C1)NC(=O)c1ccc(cc1Cl)-n1cnc2ncccc12 |r| Show InChI InChI=1S/C23H18Cl2N8O2/c24-15-8-13(33-11-29-21-17(33)2-1-6-27-21)3-4-14(15)23(34)30-12-5-7-32(10-12)22-19-18(16(25)9-28-22)20(26)31-35-19/h1-4,6,8-9,11-12H,5,7,10H2,(H2,26,31)(H,30,34)/t12-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Mochida Pharmaceutical Co. Ltd. Curated by ChEMBL					Assay Description Inhibition of human coagulation factor 9a using SPECTROFLUOR F9a as substrate after 60 mins by fluorescence assay				Bioorg Med Chem Lett 27: 2622-2628 (2017) Article DOI: 10.1016/j.bmcl.2017.03.002 BindingDB Entry DOI: 10.7270/Q28054RH
					More data for this Ligand-Target Pair
Coagulation factor IX (Homo sapiens (Human))	BDBM50240471 (CHEMBL4069082 | US9969724, Example 45) Show SMILES Cn1ncn(-c2ccc(C(=O)N[C@@H]3CCN(C3)c3ncc(Cl)c4c(N)noc34)c(Cl)c2)c1=O |r| Show InChI InChI=1S/C20H18Cl2N8O3/c1-28-20(32)30(9-25-28)11-2-3-12(13(21)6-11)19(31)26-10-4-5-29(8-10)18-16-15(14(22)7-24-18)17(23)27-33-16/h2-3,6-7,9-10H,4-5,8H2,1H3,(H2,23,27)(H,26,31)/t10-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Mochida Pharmaceutical Co. Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against human plasma renin at pH 7.4				Bioorg Med Chem Lett 27: 2622-2628 (2017) Article DOI: 10.1016/j.bmcl.2017.03.002 BindingDB Entry DOI: 10.7270/Q28054RH
					More data for this Ligand-Target Pair
Coagulation factor IX (Homo sapiens (Human))	BDBM50240472 (CHEMBL4090664) Show SMILES Nc1noc2c(cc(Cl)cc12)N1CCC(C1)NC(=O)c1ccc(cc1Cl)-n1cnnc1 Show InChI InChI=1S/C20H17Cl2N7O2/c21-11-5-15-18(31-27-19(15)23)17(6-11)28-4-3-12(8-28)26-20(30)14-2-1-13(7-16(14)22)29-9-24-25-10-29/h1-2,5-7,9-10,12H,3-4,8H2,(H2,23,27)(H,26,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Mochida Pharmaceutical Co. Ltd. Curated by ChEMBL					Assay Description Inhibition of human coagulation factor 9a using SPECTROFLUOR F9a as substrate after 60 mins by fluorescence assay				Bioorg Med Chem Lett 27: 2622-2628 (2017) Article DOI: 10.1016/j.bmcl.2017.03.002 BindingDB Entry DOI: 10.7270/Q28054RH
					More data for this Ligand-Target Pair
Coagulation factor IX (Homo sapiens (Human))	BDBM50240473 (CHEMBL4095415) Show SMILES Cn1cc(ccc1=O)-c1ccc(C(=O)N[C@@H]2CCN(C2)c2ncc(Cl)c3c(N)noc23)c(Cl)c1 |r| Show InChI InChI=1S/C23H20Cl2N6O3/c1-30-10-13(3-5-18(30)32)12-2-4-15(16(24)8-12)23(33)28-14-6-7-31(11-14)22-20-19(17(25)9-27-22)21(26)29-34-20/h2-5,8-10,14H,6-7,11H2,1H3,(H2,26,29)(H,28,33)/t14-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Mochida Pharmaceutical Co. Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against purified human renal renin at pH 6.5				Bioorg Med Chem Lett 27: 2622-2628 (2017) Article DOI: 10.1016/j.bmcl.2017.03.002 BindingDB Entry DOI: 10.7270/Q28054RH
					More data for this Ligand-Target Pair
Coagulation factor IX (Homo sapiens (Human))	BDBM50240489 (CHEMBL4101793 | US9969724, Example 20) Show SMILES Nc1noc2c(ncc(Cl)c12)N1CC[C@H](C1)NC(=O)c1ccc(cc1Cl)-c1cncnc1 |r| Show InChI InChI=1S/C21H17Cl2N7O2/c22-15-5-11(12-6-25-10-26-7-12)1-2-14(15)21(31)28-13-3-4-30(9-13)20-18-17(16(23)8-27-20)19(24)29-32-18/h1-2,5-8,10,13H,3-4,9H2,(H2,24,29)(H,28,31)/t13-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Mochida Pharmaceutical Co. Ltd. Curated by ChEMBL					Assay Description Inhibition of human coagulation factor 9a using SPECTROFLUOR F9a as substrate after 60 mins by fluorescence assay				Bioorg Med Chem Lett 27: 2622-2628 (2017) Article DOI: 10.1016/j.bmcl.2017.03.002 BindingDB Entry DOI: 10.7270/Q28054RH
					More data for this Ligand-Target Pair
Coagulation factor IX (Homo sapiens (Human))	BDBM50240474 (CHEMBL4082857) Show SMILES Nc1noc2c(ncc(Cl)c12)N1CC[C@H](C1)NC(=O)c1ccc(cc1Cl)-n1cnnc1 |r| Show InChI InChI=1S/C19H16Cl2N8O2/c20-13-5-11(29-8-24-25-9-29)1-2-12(13)19(30)26-10-3-4-28(7-10)18-16-15(14(21)6-23-18)17(22)27-31-16/h1-2,5-6,8-10H,3-4,7H2,(H2,22,27)(H,26,30)/t10-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
Mochida Pharmaceutical Co. Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against human plasma renin at pH 7.4				Bioorg Med Chem Lett 27: 2622-2628 (2017) Article DOI: 10.1016/j.bmcl.2017.03.002 BindingDB Entry DOI: 10.7270/Q28054RH
					More data for this Ligand-Target Pair
Coagulation factor IX (Homo sapiens (Human))	BDBM50240475 (CHEMBL4080361 | US9969724, Example 9) Show SMILES Nc1noc2c(ccc(Cl)c12)N1CC[C@H](C1)NC(=O)c1ccc(cc1Cl)-n1cnnc1 |r| Show InChI InChI=1S/C20H17Cl2N7O2/c21-14-3-4-16(18-17(14)19(23)27-31-18)28-6-5-11(8-28)26-20(30)13-2-1-12(7-15(13)22)29-9-24-25-10-29/h1-4,7,9-11H,5-6,8H2,(H2,23,27)(H,26,30)/t11-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
Mochida Pharmaceutical Co. Ltd. Curated by ChEMBL					Assay Description Inhibition of human coagulation factor 9a using SPECTROFLUOR F9a as substrate after 60 mins by fluorescence assay				Bioorg Med Chem Lett 27: 2622-2628 (2017) Article DOI: 10.1016/j.bmcl.2017.03.002 BindingDB Entry DOI: 10.7270/Q28054RH
					More data for this Ligand-Target Pair
Coagulation factor IX (Homo sapiens (Human))	BDBM50240476 (CHEMBL4087720 | US9969724, Example 29) Show SMILES Nc1noc2c(ncc(Cl)c12)N1CC[C@H](C1)NC(=O)c1ccc(cc1Cl)-n1cnc2ccccc12 |r| Show InChI InChI=1S/C24H19Cl2N7O2/c25-16-9-14(33-12-29-18-3-1-2-4-19(18)33)5-6-15(16)24(34)30-13-7-8-32(11-13)23-21-20(17(26)10-28-23)22(27)31-35-21/h1-6,9-10,12-13H,7-8,11H2,(H2,27,31)(H,30,34)/t13-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
Mochida Pharmaceutical Co. Ltd. Curated by ChEMBL					Assay Description Inhibition of human coagulation factor 9a using SPECTROFLUOR F9a as substrate after 60 mins by fluorescence assay				Bioorg Med Chem Lett 27: 2622-2628 (2017) Article DOI: 10.1016/j.bmcl.2017.03.002 BindingDB Entry DOI: 10.7270/Q28054RH
					More data for this Ligand-Target Pair
Coagulation factor IX (Homo sapiens (Human))	BDBM50240491 (CHEMBL4065316 | US9969724, Example 11) Show SMILES Cc1ncn(n1)-c1ccc(C(=O)N[C@@H]2CCN(C2)c2ncc(Cl)c3c(N)noc23)c(Cl)c1 |r| Show InChI InChI=1S/C20H18Cl2N8O2/c1-10-25-9-30(27-10)12-2-3-13(14(21)6-12)20(31)26-11-4-5-29(8-11)19-17-16(15(22)7-24-19)18(23)28-32-17/h2-3,6-7,9,11H,4-5,8H2,1H3,(H2,23,28)(H,26,31)/t11-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
Mochida Pharmaceutical Co. Ltd. Curated by ChEMBL					Assay Description Inhibition of human coagulation factor 9a using SPECTROFLUOR F9a as substrate after 60 mins by fluorescence assay				Bioorg Med Chem Lett 27: 2622-2628 (2017) Article DOI: 10.1016/j.bmcl.2017.03.002 BindingDB Entry DOI: 10.7270/Q28054RH
					More data for this Ligand-Target Pair
Coagulation factor IX (Homo sapiens (Human))	BDBM50240477 (CHEMBL4074983 | US9969724, Example 44) Show SMILES Cn1cc(cnc1=O)-c1ccc(C(=O)N[C@@H]2CCN(C2)c2ncc(Cl)c3c(N)noc23)c(Cl)c1 |r| Show InChI InChI=1S/C22H19Cl2N7O3/c1-30-9-12(7-27-22(30)33)11-2-3-14(15(23)6-11)21(32)28-13-4-5-31(10-13)20-18-17(16(24)8-26-20)19(25)29-34-18/h2-3,6-9,13H,4-5,10H2,1H3,(H2,25,29)(H,28,32)/t13-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
Mochida Pharmaceutical Co. Ltd. Curated by ChEMBL					Assay Description Inhibition of human coagulation factor 9a using SPECTROFLUOR F9a as substrate after 60 mins by fluorescence assay				Bioorg Med Chem Lett 27: 2622-2628 (2017) Article DOI: 10.1016/j.bmcl.2017.03.002 BindingDB Entry DOI: 10.7270/Q28054RH
					More data for this Ligand-Target Pair
Coagulation factor IX (Homo sapiens (Human))	BDBM50240478 (CHEMBL4083789) Show SMILES Cc1cc2c(N)noc2c(n1)N1CC[C@H](C1)NC(=O)c1ccc(cc1Cl)-n1cnnc1 |r| Show InChI InChI=1S/C20H19ClN8O2/c1-11-6-15-17(31-27-18(15)22)19(25-11)28-5-4-12(8-28)26-20(30)14-3-2-13(7-16(14)21)29-9-23-24-10-29/h2-3,6-7,9-10,12H,4-5,8H2,1H3,(H2,22,27)(H,26,30)/t12-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
Mochida Pharmaceutical Co. Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against human plasma renin at pH 7.4				Bioorg Med Chem Lett 27: 2622-2628 (2017) Article DOI: 10.1016/j.bmcl.2017.03.002 BindingDB Entry DOI: 10.7270/Q28054RH
					More data for this Ligand-Target Pair
Coagulation factor IX (Homo sapiens (Human))	BDBM50240493 (CHEMBL4085239 | US9969724, Example 28) Show SMILES Nc1noc2c(ncc(Cl)c12)N1CC[C@H](C1)NC(=O)c1ccc(cc1Cl)-n1cnnc1C(F)F |r| Show InChI InChI=1S/C20H16Cl2F2N8O2/c21-12-5-10(32-8-27-29-19(32)16(23)24)1-2-11(12)20(33)28-9-3-4-31(7-9)18-15-14(13(22)6-26-18)17(25)30-34-15/h1-2,5-6,8-9,16H,3-4,7H2,(H2,25,30)(H,28,33)/t9-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
Mochida Pharmaceutical Co. Ltd. Curated by ChEMBL					Assay Description Inhibition of human coagulation factor 9a using SPECTROFLUOR F9a as substrate after 60 mins by fluorescence assay				Bioorg Med Chem Lett 27: 2622-2628 (2017) Article DOI: 10.1016/j.bmcl.2017.03.002 BindingDB Entry DOI: 10.7270/Q28054RH
					More data for this Ligand-Target Pair
Coagulation factor IX (Homo sapiens (Human))	BDBM50240479 (CHEMBL4072364 | US9969724, Example 14) Show SMILES Nc1noc2c(cc(Cl)c(Cl)c12)N1CC[C@H](C1)NC(=O)c1ccc(cc1Cl)-n1cnnc1 |r| Show InChI InChI=1S/C20H16Cl3N7O2/c21-13-5-11(30-8-25-26-9-30)1-2-12(13)20(31)27-10-3-4-29(7-10)15-6-14(22)17(23)16-18(15)32-28-19(16)24/h1-2,5-6,8-10H,3-4,7H2,(H2,24,28)(H,27,31)/t10-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
Mochida Pharmaceutical Co. Ltd. Curated by ChEMBL					Assay Description Inhibition of human coagulation factor 9a using SPECTROFLUOR F9a as substrate after 60 mins by fluorescence assay				Bioorg Med Chem Lett 27: 2622-2628 (2017) Article DOI: 10.1016/j.bmcl.2017.03.002 BindingDB Entry DOI: 10.7270/Q28054RH
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM445277 (US10669239, Compound 12 | US10669239, Compound 14) Show SMILES Cc1cc(NC(=O)NC2[C@H](O)CC(C)(C)c3ccccc23)c(nc1-c1ccc(nc1)S(C)(=O)=O)-c1ccccc1 |r| Show InChI InChI=1S/C31H32N4O4S/c1-19-16-24(33-30(37)35-29-22-12-8-9-13-23(22)31(2,3)17-25(29)36)28(20-10-6-5-7-11-20)34-27(19)21-14-15-26(32-18-21)40(4,38)39/h5-16,18,25,29,36H,17H2,1-4H3,(H2,33,35,37)/t25-,29?/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10669239 (2020) BindingDB Entry DOI: 10.7270/Q2T72MGZ
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM445278 (US10669239, Compound 13) Show SMILES Cc1cc(NC(=O)NC2[C@H](O)CC(C)(C)c3ccccc23)c(nc1-c1ccc(nc1)C#N)-c1ccccc1 |r| Show InChI InChI=1S/C31H29N5O2/c1-19-15-25(34-30(38)36-29-23-11-7-8-12-24(23)31(2,3)16-26(29)37)28(20-9-5-4-6-10-20)35-27(19)21-13-14-22(17-32)33-18-21/h4-15,18,26,29,37H,16H2,1-3H3,(H2,34,36,38)/t26-,29?/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10669239 (2020) BindingDB Entry DOI: 10.7270/Q2T72MGZ
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM445277 (US10669239, Compound 12 | US10669239, Compound 14) Show SMILES Cc1cc(NC(=O)NC2[C@H](O)CC(C)(C)c3ccccc23)c(nc1-c1ccc(nc1)S(C)(=O)=O)-c1ccccc1 |r| Show InChI InChI=1S/C31H32N4O4S/c1-19-16-24(33-30(37)35-29-22-12-8-9-13-23(22)31(2,3)17-25(29)36)28(20-10-6-5-7-11-20)34-27(19)21-14-15-26(32-18-21)40(4,38)39/h5-16,18,25,29,36H,17H2,1-4H3,(H2,33,35,37)/t25-,29?/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10669239 (2020) BindingDB Entry DOI: 10.7270/Q2T72MGZ
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM445280 (US10669239, Compound 15) Show SMILES Cc1cc(NC(=O)NC2[C@H](O)CC(C)(C)c3ccccc23)c(nc1-c1cnc(nc1)S(F)(F)F)-c1ccccc1 |r| Show InChI InChI=1S/C29H28F3N5O2S/c1-17-13-22(35-27(39)37-26-20-11-7-8-12-21(20)29(2,3)14-23(26)38)25(18-9-5-4-6-10-18)36-24(17)19-15-33-28(34-16-19)40(30,31)32/h4-13,15-16,23,26,38H,14H2,1-3H3,(H2,35,37,39)/t23-,26?/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10669239 (2020) BindingDB Entry DOI: 10.7270/Q2T72MGZ
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM412277 (US10399945, Example 16 | US10669239, Compound 16 |...) Show SMILES Cc1cc(NC(=O)N[C@H]2[C@H](O)CC(C)(C)c3ccccc23)c(nc1-c1ccc(cc1)C#N)-c1ccccc1 |r| Show InChI InChI=1S/C32H30N4O2/c1-20-17-26(34-31(38)36-30-24-11-7-8-12-25(24)32(2,3)18-27(30)37)29(22-9-5-4-6-10-22)35-28(20)23-15-13-21(19-33)14-16-23/h4-17,27,30,37H,18H2,1-3H3,(H2,34,36,38)/t27-,30-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10669239 (2020) BindingDB Entry DOI: 10.7270/Q2T72MGZ
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM412278 (US10399945, Example 17 | US10669239, Compound 17 |...) Show SMILES Cc1cc(NC(=O)N[C@H]2[C@H](O)CC(C)(C)c3ccccc23)c(nc1-c1ccnc(c1)C(F)(F)F)-c1ccccc1 |r| Show InChI InChI=1S/C31H29F3N4O2/c1-18-15-23(36-29(40)38-28-21-11-7-8-12-22(21)30(2,3)17-24(28)39)27(19-9-5-4-6-10-19)37-26(18)20-13-14-35-25(16-20)31(32,33)34/h4-16,24,28,39H,17H2,1-3H3,(H2,36,38,40)/t24-,28-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10669239 (2020) BindingDB Entry DOI: 10.7270/Q2T72MGZ
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM412265 (US10399945, Example 10 | US10399945, Example 4 | U...) Show SMILES Cc1cc(NC(=O)N[C@H]2[C@H](O)CC(C)(C)c3ccccc23)c(nc1-c1cnn(C)c1)-c1ccccc1 |r| Show InChI InChI=1S/C29H31N5O2/c1-18-14-23(26(19-10-6-5-7-11-19)32-25(18)20-16-30-34(4)17-20)31-28(36)33-27-21-12-8-9-13-22(21)29(2,3)15-24(27)35/h5-14,16-17,24,27,35H,15H2,1-4H3,(H2,31,33,36)/t24-,27-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10669239 (2020) BindingDB Entry DOI: 10.7270/Q2T72MGZ
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM412280 (US10399945, Example 19 | US10669239, Compound 19 |...) Show SMILES Cc1cc(NC(=O)N[C@H]2[C@H](O)CC(C)(C)c3ccccc23)c(nc1-c1cnc(O)nc1)-c1ccccc1 |r| Show InChI InChI=1S/C29H29N5O3/c1-17-13-22(25(18-9-5-4-6-10-18)33-24(17)19-15-30-27(36)31-16-19)32-28(37)34-26-20-11-7-8-12-21(20)29(2,3)14-23(26)35/h4-13,15-16,23,26,35H,14H2,1-3H3,(H,30,31,36)(H2,32,34,37)/t23-,26-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10669239 (2020) BindingDB Entry DOI: 10.7270/Q2T72MGZ
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM412267 (US10399945, Example 6 | US10669239, Compound 20 | ...) Show SMILES Cc1cc(NC(=O)N[C@H]2[C@H](O)CC(C)(C)c3ccccc23)c(nc1-c1ccc(O)nc1)-c1ccccc1 |r| Show InChI InChI=1S/C30H30N4O3/c1-18-15-23(27(19-9-5-4-6-10-19)33-26(18)20-13-14-25(36)31-17-20)32-29(37)34-28-21-11-7-8-12-22(21)30(2,3)16-24(28)35/h4-15,17,24,28,35H,16H2,1-3H3,(H,31,36)(H2,32,34,37)/t24-,28-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10669239 (2020) BindingDB Entry DOI: 10.7270/Q2T72MGZ
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM445286 (US10669239, Compound 21) Show SMILES Cc1cc(NC(=O)N[C@H]2[C@H](O)CC(C)(C)c3ccccc23)c(nc1-c1cnc(nc1)C(C)(C)O)-c1ccccc1 |r| Show InChI InChI=1S/C32H35N5O3/c1-19-15-24(35-30(39)37-28-22-13-9-10-14-23(22)31(2,3)16-25(28)38)27(20-11-7-6-8-12-20)36-26(19)21-17-33-29(34-18-21)32(4,5)40/h6-15,17-18,25,28,38,40H,16H2,1-5H3,(H2,35,37,39)/t25-,28-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10669239 (2020) BindingDB Entry DOI: 10.7270/Q2T72MGZ
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM412283 (US10399945, Example 22 | US10669239, Compound 22 |...) Show SMILES Cc1cnc(c(NC(=O)N[C@H]2[C@H](O)CC(C)(C)c3cc(Br)ccc23)c1)-c1ccccc1 |r| Show InChI InChI=1S/C25H26BrN3O2/c1-15-11-20(22(27-14-15)16-7-5-4-6-8-16)28-24(31)29-23-18-10-9-17(26)12-19(18)25(2,3)13-21(23)30/h4-12,14,21,23,30H,13H2,1-3H3,(H2,28,29,31)/t21-,23-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10669239 (2020) BindingDB Entry DOI: 10.7270/Q2T72MGZ
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM412284 (US10399945, Example 23 | US10669239, Compound 23 |...) Show SMILES Cc1cc(NC(=O)N[C@H]2[C@H](O)CC(C)(C)c3cc(Br)ccc23)c(nc1C(N)=O)-c1ccccc1 |r| Show InChI InChI=1S/C26H27BrN4O3/c1-14-11-19(22(30-21(14)24(28)33)15-7-5-4-6-8-15)29-25(34)31-23-17-10-9-16(27)12-18(17)26(2,3)13-20(23)32/h4-12,20,23,32H,13H2,1-3H3,(H2,28,33)(H2,29,31,34)/t20-,23-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10669239 (2020) BindingDB Entry DOI: 10.7270/Q2T72MGZ
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM412285 (US10399945, Example 24 | US10669239, Compound 24 |...) Show SMILES Cc1cc(NC(=O)N[C@H]2[C@H](O)CC(C)(C)c3ccccc23)c(nc1C(N)=O)-c1ccccc1 |r| Show InChI InChI=1S/C26H28N4O3/c1-15-13-19(22(29-21(15)24(27)32)16-9-5-4-6-10-16)28-25(33)30-23-17-11-7-8-12-18(17)26(2,3)14-20(23)31/h4-13,20,23,31H,14H2,1-3H3,(H2,27,32)(H2,28,30,33)/t20-,23-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10669239 (2020) BindingDB Entry DOI: 10.7270/Q2T72MGZ
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM412286 (US10399945, Example 25 | US10669239, Compound 25 |...) Show SMILES Cc1cc(NC(=O)N[C@H]2[C@H](O)CC(C)(C)c3ccccc23)c(nc1C(=O)NCC(C)(C)O)-c1ccccc1 |r| Show InChI InChI=1S/C30H36N4O4/c1-18-15-22(25(19-11-7-6-8-12-19)33-24(18)27(36)31-17-30(4,5)38)32-28(37)34-26-20-13-9-10-14-21(20)29(2,3)16-23(26)35/h6-15,23,26,35,38H,16-17H2,1-5H3,(H,31,36)(H2,32,34,37)/t23-,26-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10669239 (2020) BindingDB Entry DOI: 10.7270/Q2T72MGZ
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM412287 (US10399945, Example 26 | US10669239, Compound 26 |...) Show SMILES Cc1cnc(C2CCOCC2)c(NC(=O)N[C@H]2[C@H](O)CC(C)(C)c3ccccc23)c1 |r| Show InChI InChI=1S/C24H31N3O3/c1-15-12-19(21(25-14-15)16-8-10-30-11-9-16)26-23(29)27-22-17-6-4-5-7-18(17)24(2,3)13-20(22)28/h4-7,12,14,16,20,22,28H,8-11,13H2,1-3H3,(H2,26,27,29)/t20-,22-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10669239 (2020) BindingDB Entry DOI: 10.7270/Q2T72MGZ
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM412289 (US10399945, Example 28 | US10669239, Compound 28 |...) Show SMILES Cc1ncc(cn1)-c1nc(C2CCOCC2)c(NC(=O)N[C@H]2[C@H](O)CC(C)(C)c3ccccc23)cc1C |r| Show InChI InChI=1S/C29H35N5O3/c1-17-13-23(26(19-9-11-37-12-10-19)33-25(17)20-15-30-18(2)31-16-20)32-28(36)34-27-21-7-5-6-8-22(21)29(3,4)14-24(27)35/h5-8,13,15-16,19,24,27,35H,9-12,14H2,1-4H3,(H2,32,34,36)/t24-,27-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10669239 (2020) BindingDB Entry DOI: 10.7270/Q2T72MGZ
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM412299 (US10399945, Example 36 | US10669239, Compound 36 |...) Show SMILES CC1(C)C[C@@H](O)[C@H](NC(=O)Nc2cccnc2-c2ccccc2)c2cc(F)c(F)cc12 |r| Show InChI InChI=1S/C24H23F2N3O2/c1-24(2)13-20(30)22(15-11-17(25)18(26)12-16(15)24)29-23(31)28-19-9-6-10-27-21(19)14-7-4-3-5-8-14/h3-12,20,22,30H,13H2,1-2H3,(H2,28,29,31)/t20-,22-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10669239 (2020) BindingDB Entry DOI: 10.7270/Q2T72MGZ
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM445331 (US10669239, Compound 56 | US10927079, Compound 56) Show SMILES Cc1cc(NC(=O)N[C@H]2[C@H](O)CC(C)(C)c3cc(F)c(F)cc23)c(nc1-c1ccnc(CO)c1)-c1ccccc1 |r| Show InChI InChI=1S/C31H30F2N4O3/c1-17-11-25(28(18-7-5-4-6-8-18)36-27(17)19-9-10-34-20(12-19)16-38)35-30(40)37-29-21-13-23(32)24(33)14-22(21)31(2,3)15-26(29)39/h4-14,26,29,38-39H,15-16H2,1-3H3,(H2,35,37,40)/t26-,29-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10669239 (2020) BindingDB Entry DOI: 10.7270/Q2T72MGZ
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM412308 (US10399945, Example 41b | US10669239, Compound 41b) Show SMILES Cc1nnc(CNC(=O)c2nc(c(NC(=O)N[C@@H]3[C@H](O)CC(C)(C)c4cc(F)c(F)cc34)cc2C)-c2ccccc2)o1 |r| Show InChI InChI=1S/C30H30F2N6O4/c1-15-10-22(34-29(41)36-27-18-11-20(31)21(32)12-19(18)30(3,4)13-23(27)39)26(17-8-6-5-7-9-17)35-25(15)28(40)33-14-24-38-37-16(2)42-24/h5-12,23,27,39H,13-14H2,1-4H3,(H,33,40)(H2,34,36,41)/t23-,27+/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10399945 (2019) BindingDB Entry DOI: 10.7270/Q2BG2RCB
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM412309 (US10399945, Example 42 | US10669239, Compound 42 |...) Show SMILES Cc1cc(NC(=O)N[C@H]2[C@H](O)CC(C)(C)c3cc(F)c(F)cc23)c(nc1C(=O)NCC(C)(C)O)-c1ccccc1 |r| Show InChI InChI=1S/C30H34F2N4O4/c1-16-11-22(25(17-9-7-6-8-10-17)35-24(16)27(38)33-15-30(4,5)40)34-28(39)36-26-18-12-20(31)21(32)13-19(18)29(2,3)14-23(26)37/h6-13,23,26,37,40H,14-15H2,1-5H3,(H,33,38)(H2,34,36,39)/t23-,26-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10399945 (2019) BindingDB Entry DOI: 10.7270/Q2BG2RCB
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM412310 (US10399945, Example 43) Show SMILES Cc1cc(NC(=O)NC2[C@H](O)CC(C)(C)c3cc(F)c(F)cc23)c(nc1CO)-c1ccccc1 |r| Show InChI InChI=1S/C26H27F2N3O3/c1-14-9-20(23(29-21(14)13-32)15-7-5-4-6-8-15)30-25(34)31-24-16-10-18(27)19(28)11-17(16)26(2,3)12-22(24)33/h4-11,22,24,32-33H,12-13H2,1-3H3,(H2,30,31,34)/t22-,24?/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10399945 (2019) BindingDB Entry DOI: 10.7270/Q2BG2RCB
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM412311 (US10399945, Example 44 | US10399945, Example 44a |...) Show SMILES Cc1ncc(cn1)-c1nc(c(NC(=O)N[C@H]2[C@H](O)CC(C)(C)c3cc(F)c(F)cc23)cc1C)-c1ccccc1 |r| Show InChI InChI=1S/C30H29F2N5O2/c1-16-10-24(27(18-8-6-5-7-9-18)36-26(16)19-14-33-17(2)34-15-19)35-29(39)37-28-20-11-22(31)23(32)12-21(20)30(3,4)13-25(28)38/h5-12,14-15,25,28,38H,13H2,1-4H3,(H2,35,37,39)/t25-,28-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10399945 (2019) BindingDB Entry DOI: 10.7270/Q2BG2RCB
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM412311 (US10399945, Example 44 | US10399945, Example 44a |...) Show SMILES Cc1ncc(cn1)-c1nc(c(NC(=O)N[C@H]2[C@H](O)CC(C)(C)c3cc(F)c(F)cc23)cc1C)-c1ccccc1 |r| Show InChI InChI=1S/C30H29F2N5O2/c1-16-10-24(27(18-8-6-5-7-9-18)36-26(16)19-14-33-17(2)34-15-19)35-29(39)37-28-20-11-22(31)23(32)12-21(20)30(3,4)13-25(28)38/h5-12,14-15,25,28,38H,13H2,1-4H3,(H2,35,37,39)/t25-,28-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10399945 (2019) BindingDB Entry DOI: 10.7270/Q2BG2RCB
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM412313 (US10399945, Example 44b) Show SMILES Cc1cc(NC(=O)N[C@@H]2[C@H](O)CC(C)(C)c3cc(F)c(F)cc23)c(nc1-c1ccc(CO)cc1)-c1ccccc1 |r| Show InChI InChI=1S/C32H31F2N3O3/c1-18-13-26(29(20-7-5-4-6-8-20)36-28(18)21-11-9-19(17-38)10-12-21)35-31(40)37-30-22-14-24(33)25(34)15-23(22)32(2,3)16-27(30)39/h4-15,27,30,38-39H,16-17H2,1-3H3,(H2,35,37,40)/t27-,30+/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10399945 (2019) BindingDB Entry DOI: 10.7270/Q2BG2RCB
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM412314 (US10399945, Example 45) Show SMILES Cc1cc(NC(=O)NC2[C@H](O)CC(C)(C)c3cc(F)c(F)cc23)c(nc1-c1ccc(CO)cc1)-c1ccccc1 |r| Show InChI InChI=1S/C32H31F2N3O3/c1-18-13-26(29(20-7-5-4-6-8-20)36-28(18)21-11-9-19(17-38)10-12-21)35-31(40)37-30-22-14-24(33)25(34)15-23(22)32(2,3)16-27(30)39/h4-15,27,30,38-39H,16-17H2,1-3H3,(H2,35,37,40)/t27-,30?/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10399945 (2019) BindingDB Entry DOI: 10.7270/Q2BG2RCB
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM412315 (US10399945, Example 46 | US10669239, Compound 46) Show SMILES Cc1cc(NC(=O)NC2[C@H](O)CC(C)(C)c3cc(F)c(F)cc23)c(nc1-c1cccc(CO)c1)-c1ccccc1 |r| Show InChI InChI=1S/C32H31F2N3O3/c1-18-12-26(29(20-9-5-4-6-10-20)36-28(18)21-11-7-8-19(13-21)17-38)35-31(40)37-30-22-14-24(33)25(34)15-23(22)32(2,3)16-27(30)39/h4-15,27,30,38-39H,16-17H2,1-3H3,(H2,35,37,40)/t27-,30?/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10399945 (2019) BindingDB Entry DOI: 10.7270/Q2BG2RCB
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM412316 (US10399945, Example 47 | US10669239, Compound 47) Show SMILES Cc1cc(NC(=O)NC2[C@H](O)CC(C)(C)c3cc(F)c(F)cc23)c(nc1-c1cccc(c1)C#N)-c1ccccc1 |r| Show InChI InChI=1S/C32H28F2N4O2/c1-18-12-26(29(20-9-5-4-6-10-20)37-28(18)21-11-7-8-19(13-21)17-35)36-31(40)38-30-22-14-24(33)25(34)15-23(22)32(2,3)16-27(30)39/h4-15,27,30,39H,16H2,1-3H3,(H2,36,38,40)/t27-,30?/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10399945 (2019) BindingDB Entry DOI: 10.7270/Q2BG2RCB
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM412317 (US10399945, Example 48 | US10669239, Compound 48) Show SMILES Cc1cc(NC(=O)NC2[C@H](O)CC(C)(C)c3cc(F)c(F)cc23)c(nc1-c1ccn(C)n1)-c1ccccc1 |r| Show InChI InChI=1S/C29H29F2N5O2/c1-16-12-23(26(17-8-6-5-7-9-17)33-25(16)22-10-11-36(4)35-22)32-28(38)34-27-18-13-20(30)21(31)14-19(18)29(2,3)15-24(27)37/h5-14,24,27,37H,15H2,1-4H3,(H2,32,34,38)/t24-,27?/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10399945 (2019) BindingDB Entry DOI: 10.7270/Q2BG2RCB
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM412318 (US10399945, Example 48a | US10669239, Compound 48a...) Show SMILES Cc1cc(NC(=O)N[C@H]2[C@H](O)CC(C)(C)c3cc(F)c(F)cc23)c(nc1-c1ccn(C)n1)-c1ccccc1 |r| Show InChI InChI=1S/C29H29F2N5O2/c1-16-12-23(26(17-8-6-5-7-9-17)33-25(16)22-10-11-36(4)35-22)32-28(38)34-27-18-13-20(30)21(31)14-19(18)29(2,3)15-24(27)37/h5-14,24,27,37H,15H2,1-4H3,(H2,32,34,38)/t24-,27-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10399945 (2019) BindingDB Entry DOI: 10.7270/Q2BG2RCB
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM412319 (US10399945, Example 48b | US10669239, Compound 48b) Show SMILES Cc1cc(NC(=O)N[C@@H]2[C@H](O)CC(C)(C)c3cc(F)c(F)cc23)c(nc1-c1ccn(C)n1)-c1ccccc1 |r| Show InChI InChI=1S/C29H29F2N5O2/c1-16-12-23(26(17-8-6-5-7-9-17)33-25(16)22-10-11-36(4)35-22)32-28(38)34-27-18-13-20(30)21(31)14-19(18)29(2,3)15-24(27)37/h5-14,24,27,37H,15H2,1-4H3,(H2,32,34,38)/t24-,27+/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10399945 (2019) BindingDB Entry DOI: 10.7270/Q2BG2RCB
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM412320 (US10399945, Example 49 | US10927079, Compound 49) Show SMILES Cc1cc(cnn1)-c1nc(c(NC(=O)N[C@H]2[C@H](O)CC(C)(C)c3cc(F)c(F)cc23)cc1C)-c1ccccc1 |r| Show InChI InChI=1S/C30H29F2N5O2/c1-16-10-24(27(18-8-6-5-7-9-18)35-26(16)19-11-17(2)37-33-15-19)34-29(39)36-28-20-12-22(31)23(32)13-21(20)30(3,4)14-25(28)38/h5-13,15,25,28,38H,14H2,1-4H3,(H2,34,36,39)/t25-,28-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10399945 (2019) BindingDB Entry DOI: 10.7270/Q2BG2RCB
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM412322 (US10399945, Example 51 | US10669239, Compound 51 |...) Show SMILES Cc1cc(NC(=O)N[C@H]2[C@H](O)CC(C)(C)c3cc(F)c(F)cc23)c(nc1-c1cnn(C)c1)-c1ccccc1 |r| Show InChI InChI=1S/C29H29F2N5O2/c1-16-10-23(26(17-8-6-5-7-9-17)34-25(16)18-14-32-36(4)15-18)33-28(38)35-27-19-11-21(30)22(31)12-20(19)29(2,3)13-24(27)37/h5-12,14-15,24,27,37H,13H2,1-4H3,(H2,33,35,38)/t24-,27-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10399945 (2019) BindingDB Entry DOI: 10.7270/Q2BG2RCB
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM412323 (US10399945, Example 52 | US10669239, Compound 52 |...) Show SMILES Cc1cc(NC(=O)N[C@H]2[C@H](O)CC(C)(C)c3cc(F)c(F)cc23)c(nc1-c1ccc(cc1)C#N)-c1ccccc1 |r| Show InChI InChI=1S/C32H28F2N4O2/c1-18-13-26(29(20-7-5-4-6-8-20)37-28(18)21-11-9-19(17-35)10-12-21)36-31(40)38-30-22-14-24(33)25(34)15-23(22)32(2,3)16-27(30)39/h4-15,27,30,39H,16H2,1-3H3,(H2,36,38,40)/t27-,30-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10399945 (2019) BindingDB Entry DOI: 10.7270/Q2BG2RCB
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM412324 (US10399945, Example 53 | US10669239, Compound 53 |...) Show SMILES Cc1cc(NC(=O)N[C@H]2[C@H](O)CC(C)(C)c3cc(F)c(F)cc23)c(nc1-c1cn[nH]c1)-c1ccccc1 |r| Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	<50	n/a	n/a	n/a	n/a	n/a	n/a
MOCHIDA PHARMACEUTICAL CO., LTD. US Patent					Assay Description Measurement was carried out using TrkA LanthaScreen (registered trademark) Eu Kinase Binding Assay (ThermoFisher SCIENTIFIC). To a 384 well plate (Co...				US Patent US10399945 (2019) BindingDB Entry DOI: 10.7270/Q2BG2RCB
					More data for this Ligand-Target Pair

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