BindingDB PrimarySearch

Found 149 hits with Last Name = 'perez-castillo' and Initial = 'a'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A (Homo sapiens (Human))	BDBM50385902 (CHEMBL2041596) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.91E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Qu£mica M£dica (CSIC) Curated by ChEMBL					Assay Description Competitive inhibition of human recombinant PDE7A1 using 5 nM to 2 uM cAMP as substrate by Lineweaver-Burk plot analysis				J Med Chem 55: 3274-84 (2012) Article DOI: 10.1021/jm201720d BindingDB Entry DOI: 10.7270/Q2ZS2XJB
Instituto de Qu£mica M£dica (CSIC) Curated by ChEMBL					More data for this Ligand-Target Pair
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A (Homo sapiens (Human))	BDBM50385903 (CHEMBL2041614) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	7.22E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Qu£mica M£dica (CSIC) Curated by ChEMBL					Assay Description Competitive inhibition of human recombinant PDE7A1 using 5 nM to 2 uM cAMP as substrate by Lineweaver-Burk plot analysis				J Med Chem 55: 3274-84 (2012) Article DOI: 10.1021/jm201720d BindingDB Entry DOI: 10.7270/Q2ZS2XJB
Instituto de Qu£mica M£dica (CSIC) Curated by ChEMBL					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM14361 ((R,S)-Rolipram \| 4-(3-cyclopentyloxy-4-methoxy-phe...) Show SMILES COc1ccc(cc1OC1CCCC1)C1CNC(=O)C1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	83	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigaciones Biol�gicas (CSIC) Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE4D3 assessed after 60 mins by IMAP fluorescence polarization assay				J Med Chem 57: 8590-607 (2014) Article DOI: 10.1021/jm501090m BindingDB Entry DOI: 10.7270/Q2S75HXC
					More data for this Ligand-Target Pair				3D Structure (crystal)
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A (Homo sapiens (Human))	BDBM50277784 (CHEMBL484928 \| N,N,2-trimethyl-5-nitrobenzenesulfo...) Show SMILES CN(C)S(=O)(=O)c1cc(ccc1C)[N+]([O-])=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Qu£mica M£dica (CSIC) Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE7A1-mediated [3H]cAMP hydrolysis after 20 mins by scintillation proximity assay				J Med Chem 55: 3274-84 (2012) Article DOI: 10.1021/jm201720d BindingDB Entry DOI: 10.7270/Q2ZS2XJB
Instituto de Qu£mica M£dica (CSIC) Curated by ChEMBL					More data for this Ligand-Target Pair
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A (Homo sapiens (Human))	BDBM50277784 (CHEMBL484928 \| N,N,2-trimethyl-5-nitrobenzenesulfo...) Show SMILES CN(C)S(=O)(=O)c1cc(ccc1C)[N+]([O-])=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigaciones Biol�gicas (CSIC) Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE7A1 assessed as inhibition of hydrolysis of [3H]cAMP after 20 mins by scintillation proximity assay				J Med Chem 57: 8590-607 (2014) Article DOI: 10.1021/jm501090m BindingDB Entry DOI: 10.7270/Q2S75HXC
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM14361 ((R,S)-Rolipram \| 4-(3-cyclopentyloxy-4-methoxy-phe...) Show SMILES COc1ccc(cc1OC1CCCC1)C1CNC(=O)C1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	98	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigaciones Biol�gicas (CSIC) Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE4B2 assessed after 60 mins by IMAP fluorescence polarization assay				J Med Chem 57: 8590-607 (2014) Article DOI: 10.1021/jm501090m BindingDB Entry DOI: 10.7270/Q2S75HXC
					More data for this Ligand-Target Pair				3D Structure (crystal)
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A (Homo sapiens (Human))	BDBM50028886 (CHEMBL3359633) Show SMILES [O-][N+](=O)c1ccc(Sc2ccncc2)c(Cl)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigaciones Biol�gicas (CSIC) Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE7A1 assessed as inhibition of hydrolysis of [3H]cAMP after 20 mins by scintillation proximity assay				J Med Chem 57: 8590-607 (2014) Article DOI: 10.1021/jm501090m BindingDB Entry DOI: 10.7270/Q2S75HXC
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50382604 (CHEMBL2022420 \| CHEMBL2024373) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Qu£mica M£dica-CSIC Curated by ChEMBL					Assay Description Inhibition of human recombinant GSK3beta after 30 mins by luminescence assay in presence of ATP				J Med Chem 55: 1645-61 (2012) Article DOI: 10.1021/jm201463v BindingDB Entry DOI: 10.7270/Q2862HGD
Instituto de Qu£mica M£dica-CSIC Curated by ChEMBL					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50382610 (CHEMBL2022413) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Qu£mica M£dica-CSIC Curated by ChEMBL					Assay Description Inhibition of human recombinant GSK3beta after 30 mins by luminescence assay in presence of ATP				J Med Chem 55: 1645-61 (2012) Article DOI: 10.1021/jm201463v BindingDB Entry DOI: 10.7270/Q2862HGD
Instituto de Qu£mica M£dica-CSIC Curated by ChEMBL					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50382608 (CHEMBL2022415) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Qu£mica M£dica-CSIC Curated by ChEMBL					Assay Description Inhibition of human recombinant GSK3beta after 30 mins by luminescence assay in presence of ATP				J Med Chem 55: 1645-61 (2012) Article DOI: 10.1021/jm201463v BindingDB Entry DOI: 10.7270/Q2862HGD
Instituto de Qu£mica M£dica-CSIC Curated by ChEMBL					More data for this Ligand-Target Pair
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A (Homo sapiens (Human))	BDBM50028926 (CHEMBL3359624) Show SMILES Nc1ccc(Sc2ccc(Cl)cc2[N+]([O-])=O)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigaciones Biol�gicas (CSIC) Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE7A1 assessed as inhibition of hydrolysis of [3H]cAMP after 20 mins by scintillation proximity assay				J Med Chem 57: 8590-607 (2014) Article DOI: 10.1021/jm501090m BindingDB Entry DOI: 10.7270/Q2S75HXC
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50382615 (CHEMBL2024372) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Qu£mica M£dica-CSIC Curated by ChEMBL					Assay Description Inhibition of human recombinant GSK3beta after 30 mins by luminescence assay in presence of ATP				J Med Chem 55: 1645-61 (2012) Article DOI: 10.1021/jm201463v BindingDB Entry DOI: 10.7270/Q2862HGD
Instituto de Qu£mica M£dica-CSIC Curated by ChEMBL					More data for this Ligand-Target Pair
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A (Homo sapiens (Human))	BDBM50385909 (CHEMBL2041586) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	580	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Qu£mica M£dica (CSIC) Curated by ChEMBL					Assay Description Inhibition of PDE7A1				J Med Chem 55: 3274-84 (2012) Article DOI: 10.1021/jm201720d BindingDB Entry DOI: 10.7270/Q2ZS2XJB
Instituto de Qu£mica M£dica (CSIC) Curated by ChEMBL					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50382606 (CHEMBL2022418 \| CHEMBL2024361) Show SMILES OCC\N=c1/nc(-c2ccccc2)n(s1)-c1ccccc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Qu£mica M£dica-CSIC Curated by ChEMBL					Assay Description Inhibition of human recombinant GSK3beta after 30 mins by luminescence assay in presence of ATP				J Med Chem 55: 1645-61 (2012) Article DOI: 10.1021/jm201463v BindingDB Entry DOI: 10.7270/Q2862HGD
Instituto de Qu£mica M£dica-CSIC Curated by ChEMBL					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 7B (Homo sapiens (Human))	BDBM50028886 (CHEMBL3359633) Show SMILES [O-][N+](=O)c1ccc(Sc2ccncc2)c(Cl)c1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigaciones Biol�gicas (CSIC) Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE7B assessed as inhibition of hydrolysis of [3H]cAMP after 20 mins by scintillation proximity assay				J Med Chem 57: 8590-607 (2014) Article DOI: 10.1021/jm501090m BindingDB Entry DOI: 10.7270/Q2S75HXC
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50382619 (CHEMBL2022416) Show SMILES Cc1n\c(=N/Cc2cccnc2)sn1-c1ccccc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Qu£mica M£dica-CSIC Curated by ChEMBL					Assay Description Inhibition of human recombinant GSK3beta after 30 mins by luminescence assay in presence of ATP				J Med Chem 55: 1645-61 (2012) Article DOI: 10.1021/jm201463v BindingDB Entry DOI: 10.7270/Q2862HGD
Instituto de Qu£mica M£dica-CSIC Curated by ChEMBL					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50382627 (CHEMBL2024362) Show SMILES N=c1nc(-c2ccccc2)n(s1)-c1ccccc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Qu£mica M£dica-CSIC Curated by ChEMBL					Assay Description Inhibition of human recombinant GSK3beta after 30 mins by luminescence assay in presence of ATP				J Med Chem 55: 1645-61 (2012) Article DOI: 10.1021/jm201463v BindingDB Entry DOI: 10.7270/Q2862HGD
Instituto de Qu£mica M£dica-CSIC Curated by ChEMBL					More data for this Ligand-Target Pair
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A (Homo sapiens (Human))	BDBM50028887 (CHEMBL3359635) Show SMILES [O-][N+](=O)c1cc(Cl)ccc1Sc1ccncc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	720	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigaciones Biol�gicas (CSIC) Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE7A1 assessed as inhibition of hydrolysis of [3H]cAMP after 20 mins by scintillation proximity assay				J Med Chem 57: 8590-607 (2014) Article DOI: 10.1021/jm501090m BindingDB Entry DOI: 10.7270/Q2S75HXC
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50382607 (CHEMBL2022417) Show SMILES CCCCCc1n\c(=N/Cc2cccnc2)sn1-c1ccccc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Qu£mica M£dica-CSIC Curated by ChEMBL					Assay Description Inhibition of human recombinant GSK3beta after 30 mins by luminescence assay in presence of ATP				J Med Chem 55: 1645-61 (2012) Article DOI: 10.1021/jm201463v BindingDB Entry DOI: 10.7270/Q2862HGD
Instituto de Qu£mica M£dica-CSIC Curated by ChEMBL					More data for this Ligand-Target Pair
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A (Homo sapiens (Human))	BDBM77437 (1-({[5-(ethoxycarbonyl)-4-methyl-1,3-thiazol-2-yl]...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	860	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Qu£mica M£dica (CSIC) Curated by ChEMBL					Assay Description Inhibition of PDE7A1				J Med Chem 55: 3274-84 (2012) Article DOI: 10.1021/jm201720d BindingDB Entry DOI: 10.7270/Q2ZS2XJB
Instituto de Qu£mica M£dica (CSIC) Curated by ChEMBL					More data for this Ligand-Target Pair
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A (Homo sapiens (Human))	BDBM50385910 (CHEMBL2041587) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	880	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Qu£mica M£dica (CSIC) Curated by ChEMBL					Assay Description Inhibition of PDE7A1				J Med Chem 55: 3274-84 (2012) Article DOI: 10.1021/jm201720d BindingDB Entry DOI: 10.7270/Q2ZS2XJB
Instituto de Qu£mica M£dica (CSIC) Curated by ChEMBL					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50382603 (CHEMBL2022421) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Qu£mica M£dica-CSIC Curated by ChEMBL					Assay Description Inhibition of human recombinant GSK3beta after 30 mins by luminescence assay in presence of ATP				J Med Chem 55: 1645-61 (2012) Article DOI: 10.1021/jm201463v BindingDB Entry DOI: 10.7270/Q2862HGD
Instituto de Qu£mica M£dica-CSIC Curated by ChEMBL					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50382625 (CHEMBL558982) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Qu£mica M£dica-CSIC Curated by ChEMBL					Assay Description Inhibition of human recombinant GSK3beta after 30 mins by luminescence assay in presence of ATP				J Med Chem 55: 1645-61 (2012) Article DOI: 10.1021/jm201463v BindingDB Entry DOI: 10.7270/Q2862HGD
Instituto de Qu£mica M£dica-CSIC Curated by ChEMBL					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50382605 (CHEMBL2022414 \| CHEMBL2022419) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Qu£mica M£dica-CSIC Curated by ChEMBL					Assay Description Inhibition of human recombinant GSK3beta after 30 mins by luminescence assay in presence of ATP				J Med Chem 55: 1645-61 (2012) Article DOI: 10.1021/jm201463v BindingDB Entry DOI: 10.7270/Q2862HGD
Instituto de Qu£mica M£dica-CSIC Curated by ChEMBL					More data for this Ligand-Target Pair
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A (Homo sapiens (Human))	BDBM50028925 (CHEMBL3359111) Show SMILES [O-][N+](=O)c1cc(Cl)ccc1Sc1ccccc1Br Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	990	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigaciones Biol�gicas (CSIC) Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE7A1 assessed as inhibition of hydrolysis of [3H]cAMP after 20 mins by scintillation proximity assay				J Med Chem 57: 8590-607 (2014) Article DOI: 10.1021/jm501090m BindingDB Entry DOI: 10.7270/Q2S75HXC
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50382621 (CHEMBL2024367) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Qu£mica M£dica-CSIC Curated by ChEMBL					Assay Description Inhibition of human recombinant GSK3beta after 30 mins by luminescence assay in presence of ATP				J Med Chem 55: 1645-61 (2012) Article DOI: 10.1021/jm201463v BindingDB Entry DOI: 10.7270/Q2862HGD
Instituto de Qu£mica M£dica-CSIC Curated by ChEMBL					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50382620 (CHEMBL2024368) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Qu£mica M£dica-CSIC Curated by ChEMBL					Assay Description Inhibition of human recombinant GSK3beta after 30 mins by luminescence assay in presence of ATP				J Med Chem 55: 1645-61 (2012) Article DOI: 10.1021/jm201463v BindingDB Entry DOI: 10.7270/Q2862HGD
Instituto de Qu£mica M£dica-CSIC Curated by ChEMBL					More data for this Ligand-Target Pair
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A (Homo sapiens (Human))	BDBM50028917 (CHEMBL3359103) Show SMILES [O-][N+](=O)c1ccc(Cl)cc1Sc1ccccc1Br Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.01E+3	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigaciones Biol�gicas (CSIC) Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE7A1 assessed as inhibition of hydrolysis of [3H]cAMP after 20 mins by scintillation proximity assay				J Med Chem 57: 8590-607 (2014) Article DOI: 10.1021/jm501090m BindingDB Entry DOI: 10.7270/Q2S75HXC
					More data for this Ligand-Target Pair
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A/cAMP-specific 3',5'-cyclic phosphodiesterase 7B (Homo sapiens (Human))	BDBM50359737 (CHEMBL1927722) Show SMILES S=c1[nH]c2ccccc2c(=S)n1-c1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1.04E+3	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigaciones Biol�gicas (CSIC) Curated by ChEMBL					Assay Description Inhibition of PDE7 (unknown origin)				J Med Chem 57: 8590-607 (2014) Article DOI: 10.1021/jm501090m BindingDB Entry DOI: 10.7270/Q2S75HXC
					More data for this Ligand-Target Pair
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A (Homo sapiens (Human))	BDBM50359737 (CHEMBL1927722) Show SMILES S=c1[nH]c2ccccc2c(=S)n1-c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1.04E+3	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Qu£mica M£dica (CSIC) Curated by ChEMBL					Assay Description Inhibition of PDE7A assessed as hydrolysis of [3H]cAMP after 20 mins by scintillation proximity assay				Eur J Med Chem 47: 175-85 (2012) Article DOI: 10.1016/j.ejmech.2011.10.040 BindingDB Entry DOI: 10.7270/Q20G3KJS
Instituto de Qu£mica M£dica (CSIC) Curated by ChEMBL					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50382604 (CHEMBL2022420 \| CHEMBL2024373) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Qu£mica M£dica-CSIC Curated by ChEMBL					Assay Description Inhibition of human recombinant GSK3beta after 30 mins by luminescence assay in presence of ATP				J Med Chem 55: 1645-61 (2012) Article DOI: 10.1021/jm201463v BindingDB Entry DOI: 10.7270/Q2862HGD
Instituto de Qu£mica M£dica-CSIC Curated by ChEMBL					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50382613 (CHEMBL2024374) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Qu£mica M£dica-CSIC Curated by ChEMBL					Assay Description Inhibition of human recombinant GSK3beta after 30 mins by luminescence assay in presence of ATP				J Med Chem 55: 1645-61 (2012) Article DOI: 10.1021/jm201463v BindingDB Entry DOI: 10.7270/Q2862HGD
Instituto de Qu£mica M£dica-CSIC Curated by ChEMBL					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50382600 (CHEMBL2022423) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Qu£mica M£dica-CSIC Curated by ChEMBL					Assay Description Inhibition of human recombinant GSK3beta after 30 mins by luminescence assay in presence of ATP				J Med Chem 55: 1645-61 (2012) Article DOI: 10.1021/jm201463v BindingDB Entry DOI: 10.7270/Q2862HGD
Instituto de Qu£mica M£dica-CSIC Curated by ChEMBL					More data for this Ligand-Target Pair
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A/cAMP-specific 3',5'-cyclic phosphodiesterase 7B (Homo sapiens (Human))	BDBM50028894 (CHEMBL3359649) Show SMILES Br.OCC\N=c1\nc(-c2ccccc2)n(s1)-c1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.11E+3	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigaciones Biol�gicas (CSIC) Curated by ChEMBL					Assay Description Inhibition of PDE7 (unknown origin)				J Med Chem 57: 8590-607 (2014) Article DOI: 10.1021/jm501090m BindingDB Entry DOI: 10.7270/Q2S75HXC
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50382617 (CHEMBL2024370) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Qu£mica M£dica-CSIC Curated by ChEMBL					Assay Description Inhibition of human recombinant GSK3beta after 30 mins by luminescence assay in presence of ATP				J Med Chem 55: 1645-61 (2012) Article DOI: 10.1021/jm201463v BindingDB Entry DOI: 10.7270/Q2862HGD
Instituto de Qu£mica M£dica-CSIC Curated by ChEMBL					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50382616 (CHEMBL2024371) Show SMILES COc1ccc(cc1)-c1n\c(=N/CCO)sn1-c1ccccc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Qu£mica M£dica-CSIC Curated by ChEMBL					Assay Description Inhibition of human recombinant GSK3beta after 30 mins by luminescence assay in presence of ATP				J Med Chem 55: 1645-61 (2012) Article DOI: 10.1021/jm201463v BindingDB Entry DOI: 10.7270/Q2862HGD
Instituto de Qu£mica M£dica-CSIC Curated by ChEMBL					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM50277784 (CHEMBL484928 \| N,N,2-trimethyl-5-nitrobenzenesulfo...) Show SMILES CN(C)S(=O)(=O)c1cc(ccc1C)[N+]([O-])=O Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1.28E+3	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigaciones Biol�gicas (CSIC) Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE4D3 assessed after 60 mins by IMAP fluorescence polarization assay				J Med Chem 57: 8590-607 (2014) Article DOI: 10.1021/jm501090m BindingDB Entry DOI: 10.7270/Q2S75HXC
					More data for this Ligand-Target Pair
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A (Homo sapiens (Human))	BDBM50028935 (CHEMBL3359632) Show SMILES [O-][N+](=O)c1ccc(Sc2ccccn2)c(Cl)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.29E+3	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigaciones Biol�gicas (CSIC) Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE7A1 assessed as inhibition of hydrolysis of [3H]cAMP after 20 mins by scintillation proximity assay				J Med Chem 57: 8590-607 (2014) Article DOI: 10.1021/jm501090m BindingDB Entry DOI: 10.7270/Q2S75HXC
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50382630 (CHEMBL2024359) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Qu£mica M£dica-CSIC Curated by ChEMBL					Assay Description Inhibition of human recombinant GSK3beta after 30 mins by luminescence assay in presence of ATP				J Med Chem 55: 1645-61 (2012) Article DOI: 10.1021/jm201463v BindingDB Entry DOI: 10.7270/Q2862HGD
Instituto de Qu£mica M£dica-CSIC Curated by ChEMBL					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50382626 (CHEMBL2024363) Show SMILES CCCCC\N=c1/nc(-c2ccccc2)n(s1)-c1ccccc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Qu£mica M£dica-CSIC Curated by ChEMBL					Assay Description Inhibition of human recombinant GSK3beta after 30 mins by luminescence assay in presence of ATP				J Med Chem 55: 1645-61 (2012) Article DOI: 10.1021/jm201463v BindingDB Entry DOI: 10.7270/Q2862HGD
Instituto de Qu£mica M£dica-CSIC Curated by ChEMBL					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 7B (Homo sapiens (Human))	BDBM50028925 (CHEMBL3359111) Show SMILES [O-][N+](=O)c1cc(Cl)ccc1Sc1ccccc1Br Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.41E+3	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigaciones Biol�gicas (CSIC) Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE7B assessed as inhibition of hydrolysis of [3H]cAMP after 20 mins by scintillation proximity assay				J Med Chem 57: 8590-607 (2014) Article DOI: 10.1021/jm501090m BindingDB Entry DOI: 10.7270/Q2S75HXC
					More data for this Ligand-Target Pair
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A (Homo sapiens (Human))	BDBM50028916 (CHEMBL3359101) Show SMILES Nc1ccc(Sc2ccc(c(Cl)c2)[N+]([O-])=O)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.47E+3	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigaciones Biol�gicas (CSIC) Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE7A1 assessed as inhibition of hydrolysis of [3H]cAMP after 20 mins by scintillation proximity assay				J Med Chem 57: 8590-607 (2014) Article DOI: 10.1021/jm501090m BindingDB Entry DOI: 10.7270/Q2S75HXC
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 7B (Homo sapiens (Human))	BDBM50028927 (CHEMBL196910) Show SMILES [O-][N+](=O)c1cc(Cl)ccc1Sc1ccccc1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigaciones Biol�gicas (CSIC) Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE7B assessed as inhibition of hydrolysis of [3H]cAMP after 20 mins by scintillation proximity assay				J Med Chem 57: 8590-607 (2014) Article DOI: 10.1021/jm501090m BindingDB Entry DOI: 10.7270/Q2S75HXC
					More data for this Ligand-Target Pair
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A (Homo sapiens (Human))	BDBM50028927 (CHEMBL196910) Show SMILES [O-][N+](=O)c1cc(Cl)ccc1Sc1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigaciones Biol�gicas (CSIC) Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE7A1 assessed as inhibition of hydrolysis of [3H]cAMP after 20 mins by scintillation proximity assay				J Med Chem 57: 8590-607 (2014) Article DOI: 10.1021/jm501090m BindingDB Entry DOI: 10.7270/Q2S75HXC
					More data for this Ligand-Target Pair
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A (Homo sapiens (Human))	BDBM50028932 (CHEMBL3359631) Show SMILES [O-][N+](=O)c1cc(Cl)ccc1Sc1cccs1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigaciones Biol�gicas (CSIC) Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE7A1 assessed as inhibition of hydrolysis of [3H]cAMP after 20 mins by scintillation proximity assay				J Med Chem 57: 8590-607 (2014) Article DOI: 10.1021/jm501090m BindingDB Entry DOI: 10.7270/Q2S75HXC
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50382612 (CHEMBL2024375) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Qu£mica M£dica-CSIC Curated by ChEMBL					Assay Description Inhibition of human recombinant GSK3beta after 30 mins by luminescence assay in presence of ATP				J Med Chem 55: 1645-61 (2012) Article DOI: 10.1021/jm201463v BindingDB Entry DOI: 10.7270/Q2862HGD
Instituto de Qu£mica M£dica-CSIC Curated by ChEMBL					More data for this Ligand-Target Pair
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A (Homo sapiens (Human))	BDBM50359736 (CHEMBL1927721) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Qu£mica M£dica (CSIC) Curated by ChEMBL					Assay Description Inhibition of PDE7A assessed as hydrolysis of [3H]cAMP after 20 mins by scintillation proximity assay				Eur J Med Chem 47: 175-85 (2012) Article DOI: 10.1016/j.ejmech.2011.10.040 BindingDB Entry DOI: 10.7270/Q20G3KJS
Instituto de Qu£mica M£dica (CSIC) Curated by ChEMBL					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50382601 (CHEMBL2022422 \| CHEMBL2024360) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Qu£mica M£dica-CSIC Curated by ChEMBL					Assay Description Inhibition of human recombinant GSK3beta after 30 mins by luminescence assay in presence of ATP				J Med Chem 55: 1645-61 (2012) Article DOI: 10.1021/jm201463v BindingDB Entry DOI: 10.7270/Q2862HGD
Instituto de Qu£mica M£dica-CSIC Curated by ChEMBL					More data for this Ligand-Target Pair
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A (Homo sapiens (Human))	BDBM50359739 (CHEMBL1927730) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Instituto de Qu£mica M£dica (CSIC) Curated by ChEMBL					Assay Description Inhibition of PDE7A assessed as hydrolysis of [3H]cAMP after 20 mins by scintillation proximity assay				Eur J Med Chem 47: 175-85 (2012) Article DOI: 10.1016/j.ejmech.2011.10.040 BindingDB Entry DOI: 10.7270/Q20G3KJS
Instituto de Qu£mica M£dica (CSIC) Curated by ChEMBL					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50277784 (CHEMBL484928 \| N,N,2-trimethyl-5-nitrobenzenesulfo...) Show SMILES CN(C)S(=O)(=O)c1cc(ccc1C)[N+]([O-])=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigaciones Biol�gicas (CSIC) Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE4B2 assessed after 60 mins by IMAP fluorescence polarization assay				J Med Chem 57: 8590-607 (2014) Article DOI: 10.1021/jm501090m BindingDB Entry DOI: 10.7270/Q2S75HXC
					More data for this Ligand-Target Pair

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