Compile Data Set for Download or QSAR

Found 32 hits with Last Name = 'priet' and Initial = 's'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 2 (Homo sapiens (Human))	BDBM50150754 (CHEMBL3775058) Show SMILES CCn1cnc2n(Cc3ccc(Cl)cc3)c(=O)[nH]c(=O)c12 Show InChI InChI=1S/C14H13ClN4O2/c1-2-18-8-16-12-11(18)13(20)17-14(21)19(12)7-9-3-5-10(15)6-4-9/h3-6,8H,2,7H2,1H3,(H,17,20,21)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibition of GST-tagged human BRD2 bromodomain2 using H4KAc 5/8/12/16 peptide as substrate incubated overnight by HTRF assay				J Med Chem 59: 1634-41 (2016) Article DOI: 10.1021/acs.jmedchem.5b01708 BindingDB Entry DOI: 10.7270/Q21N830R
					More data for this Ligand-Target Pair
Bromodomain-containing protein 3 (Homo sapiens (Human))	BDBM50150754 (CHEMBL3775058) Show SMILES CCn1cnc2n(Cc3ccc(Cl)cc3)c(=O)[nH]c(=O)c12 Show InChI InChI=1S/C14H13ClN4O2/c1-2-18-8-16-12-11(18)13(20)17-14(21)19(12)7-9-3-5-10(15)6-4-9/h3-6,8H,2,7H2,1H3,(H,17,20,21)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibition of GST-tagged human BRD3 bromodomain1 using H4KAc 5/8/12/16 peptide as substrate incubated overnight by HTRF assay				J Med Chem 59: 1634-41 (2016) Article DOI: 10.1021/acs.jmedchem.5b01708 BindingDB Entry DOI: 10.7270/Q21N830R
					More data for this Ligand-Target Pair
Bromodomain-containing protein 3 (Homo sapiens (Human))	BDBM50150754 (CHEMBL3775058) Show SMILES CCn1cnc2n(Cc3ccc(Cl)cc3)c(=O)[nH]c(=O)c12 Show InChI InChI=1S/C14H13ClN4O2/c1-2-18-8-16-12-11(18)13(20)17-14(21)19(12)7-9-3-5-10(15)6-4-9/h3-6,8H,2,7H2,1H3,(H,17,20,21)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibition of human BRD3 bromodomain2 using H4KAc 5/8/12/16 peptide as substrate incubated overnight by HTRF assay				J Med Chem 59: 1634-41 (2016) Article DOI: 10.1021/acs.jmedchem.5b01708 BindingDB Entry DOI: 10.7270/Q21N830R
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50150754 (CHEMBL3775058) Show SMILES CCn1cnc2n(Cc3ccc(Cl)cc3)c(=O)[nH]c(=O)c12 Show InChI InChI=1S/C14H13ClN4O2/c1-2-18-8-16-12-11(18)13(20)17-14(21)19(12)7-9-3-5-10(15)6-4-9/h3-6,8H,2,7H2,1H3,(H,17,20,21)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibition of GST-tagged human BRD4 bromodomain2 using H4KAc 5/8/12/16 peptide as substrate incubated overnight by HTRF assay				J Med Chem 59: 1634-41 (2016) Article DOI: 10.1021/acs.jmedchem.5b01708 BindingDB Entry DOI: 10.7270/Q21N830R
					More data for this Ligand-Target Pair				3D Structure (crystal)
Bromodomain testis-specific protein (Homo sapiens (Human))	BDBM50150754 (CHEMBL3775058) Show SMILES CCn1cnc2n(Cc3ccc(Cl)cc3)c(=O)[nH]c(=O)c12 Show InChI InChI=1S/C14H13ClN4O2/c1-2-18-8-16-12-11(18)13(20)17-14(21)19(12)7-9-3-5-10(15)6-4-9/h3-6,8H,2,7H2,1H3,(H,17,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibition of GST-tagged human BRDT bromodomain1 using H4KAc 5/8/12/16 peptide as substrate incubated overnight by HTRF assay				J Med Chem 59: 1634-41 (2016) Article DOI: 10.1021/acs.jmedchem.5b01708 BindingDB Entry DOI: 10.7270/Q21N830R
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50150754 (CHEMBL3775058) Show SMILES CCn1cnc2n(Cc3ccc(Cl)cc3)c(=O)[nH]c(=O)c12 Show InChI InChI=1S/C14H13ClN4O2/c1-2-18-8-16-12-11(18)13(20)17-14(21)19(12)7-9-3-5-10(15)6-4-9/h3-6,8H,2,7H2,1H3,(H,17,20,21)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibition of GST-tagged human BRD4 bromodomain1 using H4KAc 5/8/12/16 peptide as substrate incubated overnight by HTRF assay				J Med Chem 59: 1634-41 (2016) Article DOI: 10.1021/acs.jmedchem.5b01708 BindingDB Entry DOI: 10.7270/Q21N830R
					More data for this Ligand-Target Pair				3D Structure (crystal)
Bromodomain-containing protein 2 (Homo sapiens (Human))	BDBM50150754 (CHEMBL3775058) Show SMILES CCn1cnc2n(Cc3ccc(Cl)cc3)c(=O)[nH]c(=O)c12 Show InChI InChI=1S/C14H13ClN4O2/c1-2-18-8-16-12-11(18)13(20)17-14(21)19(12)7-9-3-5-10(15)6-4-9/h3-6,8H,2,7H2,1H3,(H,17,20,21)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	4.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibition of GST-tagged human BRD2 bromodomain1 using H4KAc 5/8/12/16 peptide as substrate incubated overnight by HTRF assay				J Med Chem 59: 1634-41 (2016) Article DOI: 10.1021/acs.jmedchem.5b01708 BindingDB Entry DOI: 10.7270/Q21N830R
					More data for this Ligand-Target Pair
Bromodomain-containing protein 3 (Homo sapiens (Human))	BDBM50150755 (CHEMBL3775270) Show SMILES CCCCn1c2ncn(CC)c2c(=O)[nH]c1=O Show InChI InChI=1S/C11H16N4O2/c1-3-5-6-15-9-8(10(16)13-11(15)17)14(4-2)7-12-9/h7H,3-6H2,1-2H3,(H,13,16,17)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibition of GST-tagged human BRD3 bromodomain1 using H4KAc 5/8/12/16 peptide as substrate incubated overnight by HTRF assay				J Med Chem 59: 1634-41 (2016) Article DOI: 10.1021/acs.jmedchem.5b01708 BindingDB Entry DOI: 10.7270/Q21N830R
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50150069 (CHEMBL3774931) Show SMILES CCCCc1c(C)nc2nc(SCc3nc4n(CCCC)c(=O)[nH]c(=O)c4n3CC)nn2c1C Show InChI InChI=1S/C23H32N8O2S/c1-6-9-11-16-14(4)24-21-27-22(28-31(21)15(16)5)34-13-17-25-19-18(29(17)8-3)20(32)26-23(33)30(19)12-10-7-2/h6-13H2,1-5H3,(H,26,32,33)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibition of GST-tagged human BRD4 bromodomain1 using H4KAc 5/8/12/16 peptide as substrate incubated overnight by HTRF assay				J Med Chem 59: 1634-41 (2016) Article DOI: 10.1021/acs.jmedchem.5b01708 BindingDB Entry DOI: 10.7270/Q21N830R
					More data for this Ligand-Target Pair				3D Structure (crystal)
Bromodomain-containing protein 3 (Homo sapiens (Human))	BDBM50150755 (CHEMBL3775270) Show SMILES CCCCn1c2ncn(CC)c2c(=O)[nH]c1=O Show InChI InChI=1S/C11H16N4O2/c1-3-5-6-15-9-8(10(16)13-11(15)17)14(4-2)7-12-9/h7H,3-6H2,1-2H3,(H,13,16,17)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibition of human BRD3 bromodomain2 using H4KAc 5/8/12/16 peptide as substrate incubated overnight by HTRF assay				J Med Chem 59: 1634-41 (2016) Article DOI: 10.1021/acs.jmedchem.5b01708 BindingDB Entry DOI: 10.7270/Q21N830R
					More data for this Ligand-Target Pair
Bromodomain-containing protein 2 (Homo sapiens (Human))	BDBM50150755 (CHEMBL3775270) Show SMILES CCCCn1c2ncn(CC)c2c(=O)[nH]c1=O Show InChI InChI=1S/C11H16N4O2/c1-3-5-6-15-9-8(10(16)13-11(15)17)14(4-2)7-12-9/h7H,3-6H2,1-2H3,(H,13,16,17)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibition of GST-tagged human BRD2 bromodomain2 using H4KAc 5/8/12/16 peptide as substrate incubated overnight by HTRF assay				J Med Chem 59: 1634-41 (2016) Article DOI: 10.1021/acs.jmedchem.5b01708 BindingDB Entry DOI: 10.7270/Q21N830R
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50484283 (CHEMBL1830070) Show SMILES [Na;v0+].[Na;v0+].[Na;v0+].[Na;v0+].[#7]-c1ncnc2n(-[#6]-[#6]-[#8]-[#6]P([#16-])(=O)[#8]P([#8-])(=O)[#8]P([#8-])([#8-])=O)cnc12 Show InChI InChI=1S/C8H14N5O9P3S.4Na/c9-7-6-8(11-3-10-7)13(4-12-6)1-2-20-5-23(14,26)21-25(18,19)22-24(15,16)17;;;;/h3-4H,1-2,5H2,(H,14,26)(H,18,19)(H2,9,10,11)(H2,15,16,17);;;;/q;4*+1/p-4	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£s Aix-Marseille I et II Curated by ChEMBL					Assay Description Inhibition of wild-type HIV1 subtype B reverse transcriptase assessed as incorporation of [3H]dTTP				Eur J Med Chem 46: 4281-8 (2011) Article DOI: 10.1016/j.ejmech.2011.06.034 BindingDB Entry DOI: 10.7270/Q2MW2M0C
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50484282 (CHEMBL1830071) Show SMILES [Na;v0+].[Na;v0+].[Na;v0+].[Na;v0+].[#7]-c1ncnc2n(-[#6]-[#6]-[#8]-[#6]P([#8-])(=O)[#8]P([#8-])(=O)[#8]P([#8-])([#8-])=O)cnc12 Show InChI InChI=1S/C8H14N5O10P3/c9-7-6-8(11-3-10-7)13(4-12-6)1-2-21-5-24(14,15)22-26(19,20)23-25(16,17)18/h3-4H,1-2,5H2,(H,14,15)(H,19,20)(H2,9,10,11)(H2,16,17,18)/p-4	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£s Aix-Marseille I et II Curated by ChEMBL					Assay Description Inhibition of wild-type HIV1 subtype B reverse transcriptase assessed as incorporation of [3H]dTTP				Eur J Med Chem 46: 4281-8 (2011) Article DOI: 10.1016/j.ejmech.2011.06.034 BindingDB Entry DOI: 10.7270/Q2MW2M0C
					More data for this Ligand-Target Pair
Bromodomain testis-specific protein (Homo sapiens (Human))	BDBM50150755 (CHEMBL3775270) Show SMILES CCCCn1c2ncn(CC)c2c(=O)[nH]c1=O Show InChI InChI=1S/C11H16N4O2/c1-3-5-6-15-9-8(10(16)13-11(15)17)14(4-2)7-12-9/h7H,3-6H2,1-2H3,(H,13,16,17)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibition of GST-tagged human BRDT bromodomain1 using H4KAc 5/8/12/16 peptide as substrate incubated overnight by HTRF assay				J Med Chem 59: 1634-41 (2016) Article DOI: 10.1021/acs.jmedchem.5b01708 BindingDB Entry DOI: 10.7270/Q21N830R
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50150755 (CHEMBL3775270) Show SMILES CCCCn1c2ncn(CC)c2c(=O)[nH]c1=O Show InChI InChI=1S/C11H16N4O2/c1-3-5-6-15-9-8(10(16)13-11(15)17)14(4-2)7-12-9/h7H,3-6H2,1-2H3,(H,13,16,17)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibition of GST-tagged human BRD4 bromodomain2 using H4KAc 5/8/12/16 peptide as substrate incubated overnight by HTRF assay				J Med Chem 59: 1634-41 (2016) Article DOI: 10.1021/acs.jmedchem.5b01708 BindingDB Entry DOI: 10.7270/Q21N830R
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50484281 (CHEMBL1830073) Show SMILES [Na;v0+].[Na;v0+].[Na;v0+].[Na;v0+].[#6]-[#6@H](-[#6]-n1cnc2c(-[#7])ncnc12)-[#8]-[#6]P([#8-])(=O)[#8]P([#8-])(=O)[#8]P([#8-])([#8-])=O |r| Show InChI InChI=1S/C9H16N5O10P3.4Na/c1-6(2-14-4-13-7-8(10)11-3-12-9(7)14)22-5-25(15,16)23-27(20,21)24-26(17,18)19;;;;/h3-4,6H,2,5H2,1H3,(H,15,16)(H,20,21)(H2,10,11,12)(H2,17,18,19);;;;/q;4*+1/p-4/t6-;;;;/m1..../s1	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.13E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£s Aix-Marseille I et II Curated by ChEMBL					Assay Description Inhibition of wild-type HIV1 subtype B reverse transcriptase assessed as incorporation of [3H]dTTP				Eur J Med Chem 46: 4281-8 (2011) Article DOI: 10.1016/j.ejmech.2011.06.034 BindingDB Entry DOI: 10.7270/Q2MW2M0C
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50150755 (CHEMBL3775270) Show SMILES CCCCn1c2ncn(CC)c2c(=O)[nH]c1=O Show InChI InChI=1S/C11H16N4O2/c1-3-5-6-15-9-8(10(16)13-11(15)17)14(4-2)7-12-9/h7H,3-6H2,1-2H3,(H,13,16,17)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibition of GST-tagged human BRD4 bromodomain1 using H4KAc 5/8/12/16 peptide as substrate incubated overnight by HTRF assay				J Med Chem 59: 1634-41 (2016) Article DOI: 10.1021/acs.jmedchem.5b01708 BindingDB Entry DOI: 10.7270/Q21N830R
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50484284 (CHEMBL1830072) Show SMILES [Na;v0+].[Na;v0+].[Na;v0+].[Na;v0+].[#6]-[#6@H](-[#6]-n1cnc2c(-[#7])ncnc12)-[#8]-[#6]P([#16-])(=O)[#8]P([#8-])(=O)[#8]P([#8-])([#8-])=O |r| Show InChI InChI=1S/C9H16N5O9P3S.4Na/c1-6(2-14-4-13-7-8(10)11-3-12-9(7)14)21-5-24(15,27)22-26(19,20)23-25(16,17)18;;;;/h3-4,6H,2,5H2,1H3,(H,15,27)(H,19,20)(H2,10,11,12)(H2,16,17,18);;;;/q;4*+1/p-4/t6-,24?;;;;/m1..../s1	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.39E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£s Aix-Marseille I et II Curated by ChEMBL					Assay Description Inhibition of wild-type HIV1 subtype B reverse transcriptase assessed as incorporation of [3H]dTTP				Eur J Med Chem 46: 4281-8 (2011) Article DOI: 10.1016/j.ejmech.2011.06.034 BindingDB Entry DOI: 10.7270/Q2MW2M0C
					More data for this Ligand-Target Pair
Bromodomain-containing protein 2 (Homo sapiens (Human))	BDBM50150755 (CHEMBL3775270) Show SMILES CCCCn1c2ncn(CC)c2c(=O)[nH]c1=O Show InChI InChI=1S/C11H16N4O2/c1-3-5-6-15-9-8(10(16)13-11(15)17)14(4-2)7-12-9/h7H,3-6H2,1-2H3,(H,13,16,17)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.88E+4	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibition of GST-tagged human BRD2 bromodomain1 using H4KAc 5/8/12/16 peptide as substrate incubated overnight by HTRF assay				J Med Chem 59: 1634-41 (2016) Article DOI: 10.1021/acs.jmedchem.5b01708 BindingDB Entry DOI: 10.7270/Q21N830R
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50150753 (CHEMBL3775772) Show SMILES CCCCc1c(C)nc2nc(SCc3nc4n(Cc5ccc(Cl)cc5)c(=O)[nH]c(=O)c4n3CC)nn2c1C Show InChI InChI=1S/C26H29ClN8O2S/c1-5-7-8-19-15(3)28-24-31-25(32-35(24)16(19)4)38-14-20-29-22-21(33(20)6-2)23(36)30-26(37)34(22)13-17-9-11-18(27)12-10-17/h9-12H,5-8,13-14H2,1-4H3,(H,30,36,37)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.04E+4	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibition of GST-tagged human BRD4 bromodomain1 using H4KAc 5/8/12/16 peptide as substrate incubated overnight by HTRF assay				J Med Chem 59: 1634-41 (2016) Article DOI: 10.1021/acs.jmedchem.5b01708 BindingDB Entry DOI: 10.7270/Q21N830R
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50150752 (CHEMBL3774900) Show SMILES CCn1c(CSc2n[nH]c(N)n2)nc2n(Cc3ccc(Cl)cc3)c(=O)[nH]c(=O)c12 Show InChI InChI=1S/C17H17ClN8O2S/c1-2-25-11(8-29-16-22-15(19)23-24-16)20-13-12(25)14(27)21-17(28)26(13)7-9-3-5-10(18)6-4-9/h3-6H,2,7-8H2,1H3,(H,21,27,28)(H3,19,22,23,24)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.64E+4	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibition of GST-tagged human BRD4 bromodomain1 using H4KAc 5/8/12/16 peptide as substrate incubated overnight by HTRF assay				J Med Chem 59: 1634-41 (2016) Article DOI: 10.1021/acs.jmedchem.5b01708 BindingDB Entry DOI: 10.7270/Q21N830R
					More data for this Ligand-Target Pair
Bromodomain-containing protein 2 (Homo sapiens (Human))	BDBM50150752 (CHEMBL3774900) Show SMILES CCn1c(CSc2n[nH]c(N)n2)nc2n(Cc3ccc(Cl)cc3)c(=O)[nH]c(=O)c12 Show InChI InChI=1S/C17H17ClN8O2S/c1-2-25-11(8-29-16-22-15(19)23-24-16)20-13-12(25)14(27)21-17(28)26(13)7-9-3-5-10(18)6-4-9/h3-6H,2,7-8H2,1H3,(H,21,27,28)(H3,19,22,23,24)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibition of GST-tagged human BRD2 bromodomain1 using H4KAc 5/8/12/16 peptide as substrate incubated overnight by HTRF assay				J Med Chem 59: 1634-41 (2016) Article DOI: 10.1021/acs.jmedchem.5b01708 BindingDB Entry DOI: 10.7270/Q21N830R
					More data for this Ligand-Target Pair
Bromodomain-containing protein 3 (Homo sapiens (Human))	BDBM50150752 (CHEMBL3774900) Show SMILES CCn1c(CSc2n[nH]c(N)n2)nc2n(Cc3ccc(Cl)cc3)c(=O)[nH]c(=O)c12 Show InChI InChI=1S/C17H17ClN8O2S/c1-2-25-11(8-29-16-22-15(19)23-24-16)20-13-12(25)14(27)21-17(28)26(13)7-9-3-5-10(18)6-4-9/h3-6H,2,7-8H2,1H3,(H,21,27,28)(H3,19,22,23,24)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.17E+4	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibition of GST-tagged human BRD3 bromodomain1 using H4KAc 5/8/12/16 peptide as substrate incubated overnight by HTRF assay				J Med Chem 59: 1634-41 (2016) Article DOI: 10.1021/acs.jmedchem.5b01708 BindingDB Entry DOI: 10.7270/Q21N830R
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50150714 (CHEMBL3775080) Show SMILES CCCCn1c2nc(CSc3n[nH]c(N)n3)n(CC)c2c(=O)[nH]c1=O Show InChI InChI=1S/C14H20N8O2S/c1-3-5-6-22-10-9(11(23)17-14(22)24)21(4-2)8(16-10)7-25-13-18-12(15)19-20-13/h3-7H2,1-2H3,(H,17,23,24)(H3,15,18,19,20)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibition of GST-tagged human BRD4 bromodomain1 using H4KAc 5/8/12/16 peptide as substrate incubated overnight by HTRF assay				J Med Chem 59: 1634-41 (2016) Article DOI: 10.1021/acs.jmedchem.5b01708 BindingDB Entry DOI: 10.7270/Q21N830R
					More data for this Ligand-Target Pair
Bromodomain-containing protein 2 (Homo sapiens (Human))	BDBM50150069 (CHEMBL3774931) Show SMILES CCCCc1c(C)nc2nc(SCc3nc4n(CCCC)c(=O)[nH]c(=O)c4n3CC)nn2c1C Show InChI InChI=1S/C23H32N8O2S/c1-6-9-11-16-14(4)24-21-27-22(28-31(21)15(16)5)34-13-17-25-19-18(29(17)8-3)20(32)26-23(33)30(19)12-10-7-2/h6-13H2,1-5H3,(H,26,32,33)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	5.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibition of GST-tagged human BRD2 bromodomain1 using H4KAc 5/8/12/16 peptide as substrate incubated overnight by HTRF assay				J Med Chem 59: 1634-41 (2016) Article DOI: 10.1021/acs.jmedchem.5b01708 BindingDB Entry DOI: 10.7270/Q21N830R
					More data for this Ligand-Target Pair
Bromodomain-containing protein 3 (Homo sapiens (Human))	BDBM50150069 (CHEMBL3774931) Show SMILES CCCCc1c(C)nc2nc(SCc3nc4n(CCCC)c(=O)[nH]c(=O)c4n3CC)nn2c1C Show InChI InChI=1S/C23H32N8O2S/c1-6-9-11-16-14(4)24-21-27-22(28-31(21)15(16)5)34-13-17-25-19-18(29(17)8-3)20(32)26-23(33)30(19)12-10-7-2/h6-13H2,1-5H3,(H,26,32,33)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	6.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibition of GST-tagged human BRD3 bromodomain1 using H4KAc 5/8/12/16 peptide as substrate incubated overnight by HTRF assay				J Med Chem 59: 1634-41 (2016) Article DOI: 10.1021/acs.jmedchem.5b01708 BindingDB Entry DOI: 10.7270/Q21N830R
					More data for this Ligand-Target Pair
Bromodomain testis-specific protein (Homo sapiens (Human))	BDBM50150069 (CHEMBL3774931) Show SMILES CCCCc1c(C)nc2nc(SCc3nc4n(CCCC)c(=O)[nH]c(=O)c4n3CC)nn2c1C Show InChI InChI=1S/C23H32N8O2S/c1-6-9-11-16-14(4)24-21-27-22(28-31(21)15(16)5)34-13-17-25-19-18(29(17)8-3)20(32)26-23(33)30(19)12-10-7-2/h6-13H2,1-5H3,(H,26,32,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibition of GST-tagged human BRDT bromodomain1 using H4KAc 5/8/12/16 peptide as substrate incubated overnight by HTRF assay				J Med Chem 59: 1634-41 (2016) Article DOI: 10.1021/acs.jmedchem.5b01708 BindingDB Entry DOI: 10.7270/Q21N830R
					More data for this Ligand-Target Pair
ATPase family AAA domain-containing protein 2 (Homo sapiens (Human))	BDBM50150069 (CHEMBL3774931) Show SMILES CCCCc1c(C)nc2nc(SCc3nc4n(CCCC)c(=O)[nH]c(=O)c4n3CC)nn2c1C Show InChI InChI=1S/C23H32N8O2S/c1-6-9-11-16-14(4)24-21-27-22(28-31(21)15(16)5)34-13-17-25-19-18(29(17)8-3)20(32)26-23(33)30(19)12-10-7-2/h6-13H2,1-5H3,(H,26,32,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibition of GST-tagged human ATAD2 using H4KAc 5/8/12/16 peptide as substrate incubated overnight by HTRF assay				J Med Chem 59: 1634-41 (2016) Article DOI: 10.1021/acs.jmedchem.5b01708 BindingDB Entry DOI: 10.7270/Q21N830R
					More data for this Ligand-Target Pair
Bromodomain testis-specific protein (Homo sapiens (Human))	BDBM50150752 (CHEMBL3774900) Show SMILES CCn1c(CSc2n[nH]c(N)n2)nc2n(Cc3ccc(Cl)cc3)c(=O)[nH]c(=O)c12 Show InChI InChI=1S/C17H17ClN8O2S/c1-2-25-11(8-29-16-22-15(19)23-24-16)20-13-12(25)14(27)21-17(28)26(13)7-9-3-5-10(18)6-4-9/h3-6H,2,7-8H2,1H3,(H,21,27,28)(H3,19,22,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibition of GST-tagged human BRDT bromodomain1 using H4KAc 5/8/12/16 peptide as substrate incubated overnight by HTRF assay				J Med Chem 59: 1634-41 (2016) Article DOI: 10.1021/acs.jmedchem.5b01708 BindingDB Entry DOI: 10.7270/Q21N830R
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1)	BDBM50553179 (CHEMBL4786487) Show SMILES COC(=O)c1c(N)c(nn1-c1ccccc1OCc1ccccc1)C#N Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of wild-type recombinant HIV-1 subtype B reverse transcriptase p66/p51 heterodimer expressed in Escherichia coli using calf thymus DNA and...				Citation and Details Article DOI: 10.1039/d0md00025f BindingDB Entry DOI: 10.7270/Q2280C84
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50150069 (CHEMBL3774931) Show SMILES CCCCc1c(C)nc2nc(SCc3nc4n(CCCC)c(=O)[nH]c(=O)c4n3CC)nn2c1C Show InChI InChI=1S/C23H32N8O2S/c1-6-9-11-16-14(4)24-21-27-22(28-31(21)15(16)5)34-13-17-25-19-18(29(17)8-3)20(32)26-23(33)30(19)12-10-7-2/h6-13H2,1-5H3,(H,26,32,33)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Binding affinity to his-tagged human BRD4 bromodomain1 by isothermal titration calorimetric analysis				J Med Chem 59: 1634-41 (2016) Article DOI: 10.1021/acs.jmedchem.5b01708 BindingDB Entry DOI: 10.7270/Q21N830R
					More data for this Ligand-Target Pair				3D Structure (crystal)
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50150754 (CHEMBL3775058) Show SMILES CCn1cnc2n(Cc3ccc(Cl)cc3)c(=O)[nH]c(=O)c12 Show InChI InChI=1S/C14H13ClN4O2/c1-2-18-8-16-12-11(18)13(20)17-14(21)19(12)7-9-3-5-10(15)6-4-9/h3-6,8H,2,7H2,1H3,(H,17,20,21)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Binding affinity to his-tagged human BRD4 bromodomain1 by isothermal titration calorimetric analysis				J Med Chem 59: 1634-41 (2016) Article DOI: 10.1021/acs.jmedchem.5b01708 BindingDB Entry DOI: 10.7270/Q21N830R
					More data for this Ligand-Target Pair				3D Structure (crystal)