Found 38 hits with Last Name = 'ramarao' and Initial = 'mk' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50205525
(4-{2-[5-Chloro-2-(2-{[(2-chlorobenzyl)sulfonyl]ami...)Show SMILES OC(=O)c1ccc(OCCc2c(CCNS(=O)(=O)Cc3ccccc3Cl)n(C(c3ccccc3)c3ccccc3)c3ccc(Cl)cc23)cc1 Show InChI InChI=1S/C39H34Cl2N2O5S/c40-31-17-20-36-34(25-31)33(22-24-48-32-18-15-29(16-19-32)39(44)45)37(21-23-42-49(46,47)26-30-13-7-8-14-35(30)41)43(36)38(27-9-3-1-4-10-27)28-11-5-2-6-12-28/h1-20,25,38,42H,21-24,26H2,(H,44,45) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 52 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of human cPLA2 alpha by GLU micelle assay |
J Med Chem 50: 1380-400 (2007)
Article DOI: 10.1021/jm061131z
BindingDB Entry DOI: 10.7270/Q23F4PB9 |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50205516
(4-{2-[5-chloro-2-(2-{[(2,4-dichlorobenzyl)sulfonyl...)Show SMILES OC(=O)c1ccc(OCCc2c(CCNS(=O)(=O)Cc3ccc(Cl)cc3Cl)n(C(c3ccccc3)c3ccccc3)c3ccc(Cl)cc23)cc1 Show InChI InChI=1S/C39H33Cl3N2O5S/c40-30-15-18-36-34(23-30)33(20-22-49-32-16-12-28(13-17-32)39(45)46)37(19-21-43-50(47,48)25-29-11-14-31(41)24-35(29)42)44(36)38(26-7-3-1-4-8-26)27-9-5-2-6-10-27/h1-18,23-24,38,43H,19-22,25H2,(H,45,46) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of human cPLA2 alpha by GLU micelle assay |
J Med Chem 50: 1380-400 (2007)
Article DOI: 10.1021/jm061131z
BindingDB Entry DOI: 10.7270/Q23F4PB9 |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50205513
(4-{2-[5-chloro-2-(2-{[(2,3-dichlorobenzyl)sulfonyl...)Show SMILES OC(=O)c1ccc(OCCc2c(CCNS(=O)(=O)Cc3cccc(Cl)c3Cl)n(C(c3ccccc3)c3ccccc3)c3ccc(Cl)cc23)cc1 Show InChI InChI=1S/C39H33Cl3N2O5S/c40-30-16-19-35-33(24-30)32(21-23-49-31-17-14-28(15-18-31)39(45)46)36(20-22-43-50(47,48)25-29-12-7-13-34(41)37(29)42)44(35)38(26-8-3-1-4-9-26)27-10-5-2-6-11-27/h1-19,24,38,43H,20-23,25H2,(H,45,46) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of human cPLA2 alpha by GLU micelle assay |
J Med Chem 50: 1380-400 (2007)
Article DOI: 10.1021/jm061131z
BindingDB Entry DOI: 10.7270/Q23F4PB9 |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50205527
(CHEMBL221504 | N-(((2S,4R)-1-(2-(2,4-difluorobenzo...)Show SMILES Fc1ccc(C(=O)c2ccccc2C(=O)N2C[C@@H](C[C@H]2CNC(=O)c2ccc(\C=C3/SC(=O)NC3=O)cc2)SC(c2ccccc2)(c2ccccc2)c2ccccc2)c(F)c1 Show InChI InChI=1S/C49H37F2N3O5S2/c50-36-24-25-41(42(51)27-36)44(55)39-18-10-11-19-40(39)47(58)54-30-38(28-37(54)29-52-45(56)32-22-20-31(21-23-32)26-43-46(57)53-48(59)60-43)61-49(33-12-4-1-5-13-33,34-14-6-2-7-15-34)35-16-8-3-9-17-35/h1-27,37-38H,28-30H2,(H,52,56)(H,53,57,59)/b43-26-/t37-,38+/m0/s1 | PDB
MMDB
KEGG
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PC cid
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| Article
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| n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of human cPLA2 alpha by GLU micelle assay |
J Med Chem 50: 1380-400 (2007)
Article DOI: 10.1021/jm061131z
BindingDB Entry DOI: 10.7270/Q23F4PB9 |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50205537
(4-(2-(1-benzhydryl-5-chloro-2-(2-(phenylmethylsulf...)Show SMILES OC(=O)c1ccc(OCCc2c(CCNS(=O)(=O)Cc3ccccc3)n(C(c3ccccc3)c3ccccc3)c3ccc(Cl)cc23)cc1 Show InChI InChI=1S/C39H35ClN2O5S/c40-32-18-21-36-35(26-32)34(23-25-47-33-19-16-31(17-20-33)39(43)44)37(22-24-41-48(45,46)27-28-10-4-1-5-11-28)42(36)38(29-12-6-2-7-13-29)30-14-8-3-9-15-30/h1-21,26,38,41H,22-25,27H2,(H,43,44) | PDB
MMDB
KEGG
UniProtKB/SwissProt
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GoogleScholar
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| CHEMBL
PC cid
PC sid
UniChem
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| Article
PubMed
| n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of human cPLA2 alpha by GLU micelle assay |
J Med Chem 50: 1380-400 (2007)
Article DOI: 10.1021/jm061131z
BindingDB Entry DOI: 10.7270/Q23F4PB9 |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50205532
(4-{2-[1-benzhydryl-5-nitro-2-(3-phenylmethanesulfo...)Show SMILES OC(=O)c1ccc(OCCc2c(CCNS(=O)(=O)Cc3ccccc3)n(C(c3ccccc3)c3ccccc3)c3ccc(cc23)[N+]([O-])=O)cc1 Show InChI InChI=1S/C39H35N3O7S/c43-39(44)31-16-19-33(20-17-31)49-25-23-34-35-26-32(42(45)46)18-21-36(35)41(38(29-12-6-2-7-13-29)30-14-8-3-9-15-30)37(34)22-24-40-50(47,48)27-28-10-4-1-5-11-28/h1-21,26,38,40H,22-25,27H2,(H,43,44) | PDB
MMDB
KEGG
UniProtKB/SwissProt
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antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
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| Article
PubMed
| n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of human cPLA2 alpha by GLU micelle assay |
J Med Chem 50: 1380-400 (2007)
Article DOI: 10.1021/jm061131z
BindingDB Entry DOI: 10.7270/Q23F4PB9 |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50205514
(4-{2-[5-chloro-2-(2-{[(4-chlorobenzyl)sulfonyl]ami...)Show SMILES OC(=O)c1ccc(OCCc2c(CCNS(=O)(=O)Cc3ccc(Cl)cc3)n(C(c3ccccc3)c3ccccc3)c3ccc(Cl)cc23)cc1 Show InChI InChI=1S/C39H34Cl2N2O5S/c40-31-15-11-27(12-16-31)26-49(46,47)42-23-21-37-34(22-24-48-33-18-13-30(14-19-33)39(44)45)35-25-32(41)17-20-36(35)43(37)38(28-7-3-1-4-8-28)29-9-5-2-6-10-29/h1-20,25,38,42H,21-24,26H2,(H,44,45) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of human cPLA2 alpha by GLU micelle assay |
J Med Chem 50: 1380-400 (2007)
Article DOI: 10.1021/jm061131z
BindingDB Entry DOI: 10.7270/Q23F4PB9 |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50205515
(4-(2-(1-benzhydryl-5-chloro-2-(2-((3,4-dichlorophe...)Show SMILES OC(=O)c1ccc(OCCc2c(CCNS(=O)(=O)Cc3ccc(Cl)c(Cl)c3)n(C(c3ccccc3)c3ccccc3)c3ccc(Cl)cc23)cc1 Show InChI InChI=1S/C39H33Cl3N2O5S/c40-30-14-18-36-33(24-30)32(20-22-49-31-15-12-29(13-16-31)39(45)46)37(19-21-43-50(47,48)25-26-11-17-34(41)35(42)23-26)44(36)38(27-7-3-1-4-8-27)28-9-5-2-6-10-28/h1-18,23-24,38,43H,19-22,25H2,(H,45,46) | PDB
MMDB
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antibodypedia
GoogleScholar
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| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
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| Article
PubMed
| n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of human cPLA2 alpha by GLU micelle assay |
J Med Chem 50: 1380-400 (2007)
Article DOI: 10.1021/jm061131z
BindingDB Entry DOI: 10.7270/Q23F4PB9 |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50205519
(4-(2-(1-benzhydryl-6-chloro-2-(2-(phenylmethylsulf...)Show SMILES OC(=O)c1ccc(OCCc2c(CCNS(=O)(=O)Cc3ccccc3)n(C(c3ccccc3)c3ccccc3)c3cc(Cl)ccc23)cc1 Show InChI InChI=1S/C39H35ClN2O5S/c40-32-18-21-34-35(23-25-47-33-19-16-31(17-20-33)39(43)44)36(22-24-41-48(45,46)27-28-10-4-1-5-11-28)42(37(34)26-32)38(29-12-6-2-7-13-29)30-14-8-3-9-15-30/h1-21,26,38,41H,22-25,27H2,(H,43,44) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 160 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of human cPLA2 alpha by GLU micelle assay |
J Med Chem 50: 1380-400 (2007)
Article DOI: 10.1021/jm061131z
BindingDB Entry DOI: 10.7270/Q23F4PB9 |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50205540
(4-{2-[5-chloro-2-(2-{[(3,5-dichlorobenzyl)sulfonyl...)Show SMILES OC(=O)c1ccc(OCCc2c(CCNS(=O)(=O)Cc3cc(Cl)cc(Cl)c3)n(C(c3ccccc3)c3ccccc3)c3ccc(Cl)cc23)cc1 Show InChI InChI=1S/C39H33Cl3N2O5S/c40-30-13-16-36-35(24-30)34(18-20-49-33-14-11-29(12-15-33)39(45)46)37(17-19-43-50(47,48)25-26-21-31(41)23-32(42)22-26)44(36)38(27-7-3-1-4-8-27)28-9-5-2-6-10-28/h1-16,21-24,38,43H,17-20,25H2,(H,45,46) | PDB
MMDB
KEGG
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DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 190 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of human cPLA2 alpha by GLU micelle assay |
J Med Chem 50: 1380-400 (2007)
Article DOI: 10.1021/jm061131z
BindingDB Entry DOI: 10.7270/Q23F4PB9 |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50205533
(4-{2-[2-{3-[(benzylsulfonyl)amino]propyl}-5-chloro...)Show SMILES OC(=O)c1ccc(OCCc2c(CCCNS(=O)(=O)Cc3ccccc3)n(C(c3ccccc3)c3ccccc3)c3ccc(Cl)cc23)cc1 Show InChI InChI=1S/C40H37ClN2O5S/c41-33-20-23-38-36(27-33)35(24-26-48-34-21-18-32(19-22-34)40(44)45)37(17-10-25-42-49(46,47)28-29-11-4-1-5-12-29)43(38)39(30-13-6-2-7-14-30)31-15-8-3-9-16-31/h1-9,11-16,18-23,27,39,42H,10,17,24-26,28H2,(H,44,45) | PDB
MMDB
KEGG
UniProtKB/SwissProt
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DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 260 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of human cPLA2 alpha by GLU micelle assay |
J Med Chem 50: 1380-400 (2007)
Article DOI: 10.1021/jm061131z
BindingDB Entry DOI: 10.7270/Q23F4PB9 |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50205539
(4-(2-(1-benzhydryl-5-chloro-2-(2-(2-phenylethylsul...)Show SMILES OC(=O)c1ccc(OCCc2c(CCNS(=O)(=O)CCc3ccccc3)n(C(c3ccccc3)c3ccccc3)c3ccc(Cl)cc23)cc1 Show InChI InChI=1S/C40H37ClN2O5S/c41-33-18-21-37-36(28-33)35(23-26-48-34-19-16-32(17-20-34)40(44)45)38(22-25-42-49(46,47)27-24-29-10-4-1-5-11-29)43(37)39(30-12-6-2-7-13-30)31-14-8-3-9-15-31/h1-21,28,39,42H,22-27H2,(H,44,45) | PDB
MMDB
KEGG
UniProtKB/SwissProt
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antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 520 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of human cPLA2 alpha by GLU micelle assay |
J Med Chem 50: 1380-400 (2007)
Article DOI: 10.1021/jm061131z
BindingDB Entry DOI: 10.7270/Q23F4PB9 |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50205511
(4-[2-(1-benzhydryl-2-{2-[(benzylsulfonyl)amino]eth...)Show SMILES OC(=O)c1ccc(OCCc2c(CCNS(=O)(=O)Cc3ccccc3)n(C(c3ccccc3)c3ccccc3)c3ccc(cc23)N2CCOCC2)cc1 Show InChI InChI=1S/C43H43N3O6S/c47-43(48)35-16-19-37(20-17-35)52-27-23-38-39-30-36(45-25-28-51-29-26-45)18-21-40(39)46(42(33-12-6-2-7-13-33)34-14-8-3-9-15-34)41(38)22-24-44-53(49,50)31-32-10-4-1-5-11-32/h1-21,30,42,44H,22-29,31H2,(H,47,48) | PDB
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of human cPLA2 alpha by GLU micelle assay |
J Med Chem 50: 1380-400 (2007)
Article DOI: 10.1021/jm061131z
BindingDB Entry DOI: 10.7270/Q23F4PB9 |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50205517
(4-[2-[5-chloro-1-(diphenylmethyl)-2-{2-[(methylsul...)Show SMILES CS(=O)(=O)NCCc1c(CCOc2ccc(cc2)C(O)=O)c2cc(Cl)ccc2n1C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C33H31ClN2O5S/c1-42(39,40)35-20-18-31-28(19-21-41-27-15-12-25(13-16-27)33(37)38)29-22-26(34)14-17-30(29)36(31)32(23-8-4-2-5-9-23)24-10-6-3-7-11-24/h2-17,22,32,35H,18-21H2,1H3,(H,37,38) | PDB
MMDB
KEGG
UniProtKB/SwissProt
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GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 650 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of human cPLA2 alpha by GLU micelle assay |
J Med Chem 50: 1380-400 (2007)
Article DOI: 10.1021/jm061131z
BindingDB Entry DOI: 10.7270/Q23F4PB9 |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50180081
(4-(2-(1-benzhydryl-5-chloro-2-methyl-1H-indol-3-yl...)Show SMILES Cc1c(CCS(=O)(=O)c2ccc(cc2)C(O)=O)c2cc(Cl)ccc2n1C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C31H26ClNO4S/c1-21-27(18-19-38(36,37)26-15-12-24(13-16-26)31(34)35)28-20-25(32)14-17-29(28)33(21)30(22-8-4-2-5-9-22)23-10-6-3-7-11-23/h2-17,20,30H,18-19H2,1H3,(H,34,35) | PDB
MMDB
KEGG
UniProtKB/SwissProt
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antibodypedia
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AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of human cPLA2 alpha by GLU micelle assay |
J Med Chem 50: 1380-400 (2007)
Article DOI: 10.1021/jm061131z
BindingDB Entry DOI: 10.7270/Q23F4PB9 |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50205534
(4-{2-[1-benzhydryl-2-({[(benzyloxy)carbonyl]amino}...)Show SMILES OC(=O)c1ccc(OCCc2c(CNC(=O)OCc3ccccc3)n(C(c3ccccc3)c3ccccc3)c3ccc(Cl)cc23)cc1 Show InChI InChI=1S/C39H33ClN2O5/c40-31-18-21-35-34(24-31)33(22-23-46-32-19-16-30(17-20-32)38(43)44)36(25-41-39(45)47-26-27-10-4-1-5-11-27)42(35)37(28-12-6-2-7-13-28)29-14-8-3-9-15-29/h1-21,24,37H,22-23,25-26H2,(H,41,45)(H,43,44) | PDB
MMDB
KEGG
UniProtKB/SwissProt
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AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of human cPLA2 alpha by GLU micelle assay |
J Med Chem 50: 1380-400 (2007)
Article DOI: 10.1021/jm061131z
BindingDB Entry DOI: 10.7270/Q23F4PB9 |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50205523
(4-{2-[2-(2-{[(benzyloxy)carbonyl]amino}ethyl)-5-ch...)Show SMILES OC(=O)c1ccc(OCCc2c(CCNC(=O)OCc3ccccc3)n(C(c3ccccc3)c3ccccc3)c3ccc(Cl)cc23)cc1 Show InChI InChI=1S/C40H35ClN2O5/c41-32-18-21-36-35(26-32)34(23-25-47-33-19-16-31(17-20-33)39(44)45)37(22-24-42-40(46)48-27-28-10-4-1-5-11-28)43(36)38(29-12-6-2-7-13-29)30-14-8-3-9-15-30/h1-21,26,38H,22-25,27H2,(H,42,46)(H,44,45) | PDB
MMDB
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of human cPLA2 alpha by GLU micelle assay |
J Med Chem 50: 1380-400 (2007)
Article DOI: 10.1021/jm061131z
BindingDB Entry DOI: 10.7270/Q23F4PB9 |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50205530
(4-{2-[1-benzhydryl-5-chloro-2-(hydroxymethyl)-1H-i...)Show SMILES OCc1c(CCOc2ccc(cc2)C(O)=O)c2cc(Cl)ccc2n1C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C31H26ClNO4/c32-24-13-16-28-27(19-24)26(17-18-37-25-14-11-23(12-15-25)31(35)36)29(20-34)33(28)30(21-7-3-1-4-8-21)22-9-5-2-6-10-22/h1-16,19,30,34H,17-18,20H2,(H,35,36) | PDB
MMDB
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of human cPLA2 alpha by GLU micelle assay |
J Med Chem 50: 1380-400 (2007)
Article DOI: 10.1021/jm061131z
BindingDB Entry DOI: 10.7270/Q23F4PB9 |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50205520
(4-[2-(1-benzhydryl-2-{2-[(benzylsulfonyl)(methyl)a...)Show SMILES CN(CCc1c(CCOc2ccc(cc2)C(O)=O)c2cc(Cl)ccc2n1C(c1ccccc1)c1ccccc1)S(=O)(=O)Cc1ccccc1 Show InChI InChI=1S/C40H37ClN2O5S/c1-42(49(46,47)28-29-11-5-2-6-12-29)25-23-38-35(24-26-48-34-20-17-32(18-21-34)40(44)45)36-27-33(41)19-22-37(36)43(38)39(30-13-7-3-8-14-30)31-15-9-4-10-16-31/h2-22,27,39H,23-26,28H2,1H3,(H,44,45) | PDB
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PC sid
UniChem
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| Article
PubMed
| n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of human cPLA2 alpha by GLU micelle assay |
J Med Chem 50: 1380-400 (2007)
Article DOI: 10.1021/jm061131z
BindingDB Entry DOI: 10.7270/Q23F4PB9 |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50180057
(4-(2-(1-benzhydryl-2-methyl-1H-indol-3-yl)ethoxy)b...)Show SMILES Cc1c(CCOc2ccc(cc2)C(O)=O)c2cc(Cl)ccc2n1C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C31H26ClNO3/c1-21-27(18-19-36-26-15-12-24(13-16-26)31(34)35)28-20-25(32)14-17-29(28)33(21)30(22-8-4-2-5-9-22)23-10-6-3-7-11-23/h2-17,20,30H,18-19H2,1H3,(H,34,35) | PDB
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| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of human cPLA2 alpha by GLU micelle assay |
J Med Chem 50: 1380-400 (2007)
Article DOI: 10.1021/jm061131z
BindingDB Entry DOI: 10.7270/Q23F4PB9 |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50205541
(4-{2-[2-[3-(benzylsulfonyl)propyl]-5-chloro-1-(dip...)Show SMILES OC(=O)c1ccc(OCCc2c(CCCS(=O)(=O)Cc3ccccc3)n(C(c3ccccc3)c3ccccc3)c3ccc(Cl)cc23)cc1 Show InChI InChI=1S/C40H36ClNO5S/c41-33-20-23-38-36(27-33)35(24-25-47-34-21-18-32(19-22-34)40(43)44)37(17-10-26-48(45,46)28-29-11-4-1-5-12-29)42(38)39(30-13-6-2-7-14-30)31-15-8-3-9-16-31/h1-9,11-16,18-23,27,39H,10,17,24-26,28H2,(H,43,44) | PDB
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PC sid
UniChem
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| Article
PubMed
| n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of human cPLA2 alpha by GLU micelle assay |
J Med Chem 50: 1380-400 (2007)
Article DOI: 10.1021/jm061131z
BindingDB Entry DOI: 10.7270/Q23F4PB9 |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50205518
(4-(2-(1-benzhydryl-5-chloro-2-(2-(phenylsulfonamid...)Show SMILES OC(=O)c1ccc(OCCc2c(CCNS(=O)(=O)c3ccccc3)n(C(c3ccccc3)c3ccccc3)c3ccc(Cl)cc23)cc1 Show InChI InChI=1S/C38H33ClN2O5S/c39-30-18-21-35-34(26-30)33(23-25-46-31-19-16-29(17-20-31)38(42)43)36(22-24-40-47(44,45)32-14-8-3-9-15-32)41(35)37(27-10-4-1-5-11-27)28-12-6-2-7-13-28/h1-21,26,37,40H,22-25H2,(H,42,43) | PDB
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PC cid
PC sid
UniChem
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| Article
PubMed
| n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of human cPLA2 alpha by GLU micelle assay |
J Med Chem 50: 1380-400 (2007)
Article DOI: 10.1021/jm061131z
BindingDB Entry DOI: 10.7270/Q23F4PB9 |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50205542
(4-[2-(1-benzhydryl-5-chloro-2-{2-[(2-phenylethyl)a...)Show SMILES OC(=O)c1ccc(OCCc2c(CCNCCc3ccccc3)n(C(c3ccccc3)c3ccccc3)c3ccc(Cl)cc23)cc1 Show InChI InChI=1S/C40H37ClN2O3/c41-33-18-21-37-36(28-33)35(24-27-46-34-19-16-32(17-20-34)40(44)45)38(23-26-42-25-22-29-10-4-1-5-11-29)43(37)39(30-12-6-2-7-13-30)31-14-8-3-9-15-31/h1-21,28,39,42H,22-27H2,(H,44,45) | PDB
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PC sid
UniChem
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| Article
PubMed
| n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of human cPLA2 alpha by GLU micelle assay |
J Med Chem 50: 1380-400 (2007)
Article DOI: 10.1021/jm061131z
BindingDB Entry DOI: 10.7270/Q23F4PB9 |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50205524
(4-[2-(1-benzhydryl-2-{[(benzylsulfonyl)amino]methy...)Show SMILES OC(=O)c1ccc(OCCc2c(CNS(=O)(=O)Cc3ccccc3)n(C(c3ccccc3)c3ccccc3)c3ccc(Cl)cc23)cc1 Show InChI InChI=1S/C38H33ClN2O5S/c39-31-18-21-35-34(24-31)33(22-23-46-32-19-16-30(17-20-32)38(42)43)36(25-40-47(44,45)26-27-10-4-1-5-11-27)41(35)37(28-12-6-2-7-13-28)29-14-8-3-9-15-29/h1-21,24,37,40H,22-23,25-26H2,(H,42,43) | PDB
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of human cPLA2 alpha by GLU micelle assay |
J Med Chem 50: 1380-400 (2007)
Article DOI: 10.1021/jm061131z
BindingDB Entry DOI: 10.7270/Q23F4PB9 |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50149408
(4-(2-Oxo-hexadecanoylamino)-butyric acid | 4-(2-ox...)Show InChI InChI=1S/C20H37NO4/c1-2-3-4-5-6-7-8-9-10-11-12-13-15-18(22)20(25)21-17-14-16-19(23)24/h2-17H2,1H3,(H,21,25)(H,23,24) | PDB
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PC cid
PC sid
UniChem
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| Article
PubMed
| n/a | n/a | 4.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of human cPLA2 alpha by GLU micelle assay |
J Med Chem 50: 1380-400 (2007)
Article DOI: 10.1021/jm061131z
BindingDB Entry DOI: 10.7270/Q23F4PB9 |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50205522
(4-[2-(1-benzyl-2-{2-[(benzylsulfonyl)amino]ethyl}-...)Show SMILES OC(=O)c1ccc(OCCc2c(CCNS(=O)(=O)Cc3ccccc3)n(Cc3ccccc3)c3ccc(Cl)cc23)cc1 Show InChI InChI=1S/C33H31ClN2O5S/c34-27-13-16-31-30(21-27)29(18-20-41-28-14-11-26(12-15-28)33(37)38)32(36(31)22-24-7-3-1-4-8-24)17-19-35-42(39,40)23-25-9-5-2-6-10-25/h1-16,21,35H,17-20,22-23H2,(H,37,38) | PDB
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| CHEMBL
PC cid
PC sid
UniChem
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| Article
PubMed
| n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of human cPLA2 alpha by GLU micelle assay |
J Med Chem 50: 1380-400 (2007)
Article DOI: 10.1021/jm061131z
BindingDB Entry DOI: 10.7270/Q23F4PB9 |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50205531
(4-{2-[1-benzhydryl-5-chloro-2-({[(2-phenylethyl)su...)Show SMILES OC(=O)c1ccc(OCCc2c(CNS(=O)(=O)CCc3ccccc3)n(C(c3ccccc3)c3ccccc3)c3ccc(Cl)cc23)cc1 Show InChI InChI=1S/C39H35ClN2O5S/c40-32-18-21-36-35(26-32)34(22-24-47-33-19-16-31(17-20-33)39(43)44)37(27-41-48(45,46)25-23-28-10-4-1-5-11-28)42(36)38(29-12-6-2-7-13-29)30-14-8-3-9-15-30/h1-21,26,38,41H,22-25,27H2,(H,43,44) | PDB
MMDB
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UniProtKB/SwissProt
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DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of human cPLA2 alpha by GLU micelle assay |
J Med Chem 50: 1380-400 (2007)
Article DOI: 10.1021/jm061131z
BindingDB Entry DOI: 10.7270/Q23F4PB9 |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50205526
(4-{2-[5-chloro-1-(diphenylmethyl)-2-(2-hydroxyethy...)Show SMILES OCCc1c(CCOc2ccc(cc2)C(O)=O)c2cc(Cl)ccc2n1C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C32H28ClNO4/c33-25-13-16-29-28(21-25)27(18-20-38-26-14-11-24(12-15-26)32(36)37)30(17-19-35)34(29)31(22-7-3-1-4-8-22)23-9-5-2-6-10-23/h1-16,21,31,35H,17-20H2,(H,36,37) | PDB
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of human cPLA2 alpha by GLU micelle assay |
J Med Chem 50: 1380-400 (2007)
Article DOI: 10.1021/jm061131z
BindingDB Entry DOI: 10.7270/Q23F4PB9 |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50205528
(4-[2-(1-benzhydryl-2-{2-[(benzylsulfonyl)(methyl)a...)Show SMILES OC(=O)c1ccc(OCCc2c(CCNC(=O)Cc3ccccc3)n(C(c3ccccc3)c3ccccc3)c3ccc(Cl)cc23)cc1 Show InChI InChI=1S/C40H35ClN2O4/c41-32-18-21-36-35(27-32)34(23-25-47-33-19-16-31(17-20-33)40(45)46)37(22-24-42-38(44)26-28-10-4-1-5-11-28)43(36)39(29-12-6-2-7-13-29)30-14-8-3-9-15-30/h1-21,27,39H,22-26H2,(H,42,44)(H,45,46) | PDB
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of human cPLA2 alpha by GLU micelle assay |
J Med Chem 50: 1380-400 (2007)
Article DOI: 10.1021/jm061131z
BindingDB Entry DOI: 10.7270/Q23F4PB9 |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50205529
(4-(2-(1-benzhydryl-5-chloro-2-(2-(phenylmethylsulf...)Show SMILES NC(=O)c1ccc(OCCc2c(CCNS(=O)(=O)Cc3ccccc3)n(C(c3ccccc3)c3ccccc3)c3ccc(Cl)cc23)cc1 Show InChI InChI=1S/C39H36ClN3O4S/c40-32-18-21-36-35(26-32)34(23-25-47-33-19-16-31(17-20-33)39(41)44)37(22-24-42-48(45,46)27-28-10-4-1-5-11-28)43(36)38(29-12-6-2-7-13-29)30-14-8-3-9-15-30/h1-21,26,38,42H,22-25,27H2,(H2,41,44) | PDB
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of human cPLA2 alpha by GLU micelle assay |
J Med Chem 50: 1380-400 (2007)
Article DOI: 10.1021/jm061131z
BindingDB Entry DOI: 10.7270/Q23F4PB9 |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50205521
(4-{2-[2-(aminomethyl)-1-benzhydryl-5-chloro-1H-ind...)Show SMILES NCc1c(CCOc2ccc(cc2)C(O)=O)c2cc(Cl)ccc2n1C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C31H27ClN2O3/c32-24-13-16-28-27(19-24)26(17-18-37-25-14-11-23(12-15-25)31(35)36)29(20-33)34(28)30(21-7-3-1-4-8-21)22-9-5-2-6-10-22/h1-16,19,30H,17-18,20,33H2,(H,35,36) | PDB
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of human cPLA2 alpha by GLU micelle assay |
J Med Chem 50: 1380-400 (2007)
Article DOI: 10.1021/jm061131z
BindingDB Entry DOI: 10.7270/Q23F4PB9 |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50205512
(4-[2-(1-benzhydryl-2-{2-[(benzylamino)sulfonyl]eth...)Show SMILES OC(=O)c1ccc(OCCc2c(CCS(=O)(=O)NCc3ccccc3)n(C(c3ccccc3)c3ccccc3)c3ccc(Cl)cc23)cc1 Show InChI InChI=1S/C39H35ClN2O5S/c40-32-18-21-36-35(26-32)34(22-24-47-33-19-16-31(17-20-33)39(43)44)37(23-25-48(45,46)41-27-28-10-4-1-5-11-28)42(36)38(29-12-6-2-7-13-29)30-14-8-3-9-15-30/h1-21,26,38,41H,22-25,27H2,(H,43,44) | PDB
MMDB
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UniProtKB/SwissProt
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antibodypedia
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AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of human cPLA2 alpha by GLU micelle assay |
J Med Chem 50: 1380-400 (2007)
Article DOI: 10.1021/jm061131z
BindingDB Entry DOI: 10.7270/Q23F4PB9 |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50205538
(3-(2-(1-benzhydryl-5-chloro-2-(2-(phenylmethylsulf...)Show SMILES OC(=O)c1cccc(OCCc2c(CCNS(=O)(=O)Cc3ccccc3)n(C(c3ccccc3)c3ccccc3)c3ccc(Cl)cc23)c1 Show InChI InChI=1S/C39H35ClN2O5S/c40-32-19-20-36-35(26-32)34(22-24-47-33-18-10-17-31(25-33)39(43)44)37(21-23-41-48(45,46)27-28-11-4-1-5-12-28)42(36)38(29-13-6-2-7-14-29)30-15-8-3-9-16-30/h1-20,25-26,38,41H,21-24,27H2,(H,43,44) | PDB
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AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.65E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of human cPLA2 alpha by GLU micelle assay |
J Med Chem 50: 1380-400 (2007)
Article DOI: 10.1021/jm061131z
BindingDB Entry DOI: 10.7270/Q23F4PB9 |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50205535
(4-{2-[2{2-[(benzylsulfonyl)amino]ethyl}-5-chloro-1...)Show SMILES OC(=O)c1ccc(OCCc2c(CCNS(=O)(=O)Cc3ccccc3)n(Cc3ccc(Cl)c(Cl)c3)c3ccc(Cl)cc23)cc1 Show InChI InChI=1S/C33H29Cl3N2O5S/c34-25-9-13-31-28(19-25)27(15-17-43-26-10-7-24(8-11-26)33(39)40)32(38(31)20-23-6-12-29(35)30(36)18-23)14-16-37-44(41,42)21-22-4-2-1-3-5-22/h1-13,18-19,37H,14-17,20-21H2,(H,39,40) | PDB
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| CHEMBL
PC cid
PC sid
UniChem
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| Article
PubMed
| n/a | n/a | 1.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of human cPLA2 alpha by GLU micelle assay |
J Med Chem 50: 1380-400 (2007)
Article DOI: 10.1021/jm061131z
BindingDB Entry DOI: 10.7270/Q23F4PB9 |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50205543
(4-{2-[3-{2-[(benzylsulfonyl)amino]ethyl}-1-(diphen...)Show SMILES OC(=O)c1ccc(OCCc2c(CCNS(=O)(=O)Cc3ccccc3)c3cc(ccc3n2C(c2ccccc2)c2ccccc2)[N+]([O-])=O)cc1 Show InChI InChI=1S/C39H35N3O7S/c43-39(44)31-16-19-33(20-17-31)49-25-23-37-34(22-24-40-50(47,48)27-28-10-4-1-5-11-28)35-26-32(42(45)46)18-21-36(35)41(37)38(29-12-6-2-7-13-29)30-14-8-3-9-15-30/h1-21,26,38,40H,22-25,27H2,(H,43,44) | PDB
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UniProtKB/SwissProt
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antibodypedia
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| CHEMBL
PC cid
PC sid
UniChem
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| Article
PubMed
| n/a | n/a | 2.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of human cPLA2 alpha by GLU micelle assay |
J Med Chem 50: 1380-400 (2007)
Article DOI: 10.1021/jm061131z
BindingDB Entry DOI: 10.7270/Q23F4PB9 |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50205536
(CHEMBL220734 | N-(2-(1-benzhydryl-5-chloro-3-(2-(4...)Show SMILES OCc1ccc(OCCc2c(CCNS(=O)(=O)Cc3ccccc3)n(C(c3ccccc3)c3ccccc3)c3ccc(Cl)cc23)cc1 Show InChI InChI=1S/C39H37ClN2O4S/c40-33-18-21-37-36(26-33)35(23-25-46-34-19-16-29(27-43)17-20-34)38(22-24-41-47(44,45)28-30-10-4-1-5-11-30)42(37)39(31-12-6-2-7-13-31)32-14-8-3-9-15-32/h1-21,26,39,41,43H,22-25,27-28H2 | PDB
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UniProtKB/SwissProt
B.MOAD
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antibodypedia
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AffyNet
| CHEMBL
PC cid
PC sid
UniChem
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| Article
PubMed
| n/a | n/a | 3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of human cPLA2 alpha by GLU micelle assay |
J Med Chem 50: 1380-400 (2007)
Article DOI: 10.1021/jm061131z
BindingDB Entry DOI: 10.7270/Q23F4PB9 |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50205544
(4-[2-(2-{2-[benzylsulfonyl)amino]ethyl}-5-chloro-1...)Show SMILES CC(C)n1c(CCNS(=O)(=O)Cc2ccccc2)c(CCOc2ccc(cc2)C(O)=O)c2cc(Cl)ccc12 Show InChI InChI=1S/C29H31ClN2O5S/c1-20(2)32-27-13-10-23(30)18-26(27)25(15-17-37-24-11-8-22(9-12-24)29(33)34)28(32)14-16-31-38(35,36)19-21-6-4-3-5-7-21/h3-13,18,20,31H,14-17,19H2,1-2H3,(H,33,34) | PDB
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UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 9.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of human cPLA2 alpha by GLU micelle assay |
J Med Chem 50: 1380-400 (2007)
Article DOI: 10.1021/jm061131z
BindingDB Entry DOI: 10.7270/Q23F4PB9 |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50205515
(4-(2-(1-benzhydryl-5-chloro-2-(2-((3,4-dichlorophe...)Show SMILES OC(=O)c1ccc(OCCc2c(CCNS(=O)(=O)Cc3ccc(Cl)c(Cl)c3)n(C(c3ccccc3)c3ccccc3)c3ccc(Cl)cc23)cc1 Show InChI InChI=1S/C39H33Cl3N2O5S/c40-30-14-18-36-33(24-30)32(20-22-49-31-15-12-29(13-16-31)39(45)46)37(19-21-43-50(47,48)25-26-11-17-34(41)35(42)23-26)44(36)38(27-7-3-1-4-8-27)28-9-5-2-6-10-28/h1-18,23-24,38,43H,19-22,25H2,(H,45,46) | PDB
MMDB
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UniProtKB/SwissProt
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antibodypedia
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| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 139 | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Binding affinity to human cPLA2 alpha by isothermal calorimetry |
J Med Chem 50: 1380-400 (2007)
Article DOI: 10.1021/jm061131z
BindingDB Entry DOI: 10.7270/Q23F4PB9 |
More data for this
Ligand-Target Pair | |
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