Compile Data Set for Download or QSAR

Found 45 hits with Last Name = 'stark' and Initial = 'kc'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thrombopoietin receptor (Homo sapiens (Human))	BDBM50105938 (4-{N'-[1-(3,4-Dimethyl-phenyl)-3-ethoxy-5-oxo-1,5-...) Show SMILES CCOc1[nH]n(-c2ccc(C)c(C)c2)c(=O)c1N=Nc1c(O)cc(c2ccccc12)S(O)(=O)=O |w:18.20| Show InChI InChI=1S/C23H22N4O6S/c1-4-33-22-21(23(29)27(26-22)15-10-9-13(2)14(3)11-15)25-24-20-17-8-6-5-7-16(17)19(12-18(20)28)34(30,31)32/h5-12,26,28H,4H2,1-3H3,(H,30,31,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	600	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cells				J Med Chem 44: 3730-45 (2001) BindingDB Entry DOI: 10.7270/Q2MP52KF
					More data for this Ligand-Target Pair
Thrombopoietin receptor (Homo sapiens (Human))	BDBM50105963 (4-{N'-[1-(3,4-Dimethyl-phenyl)-3-methyl-5-oxo-1,5-...) Show SMILES Cc1[nH]n(-c2ccc(C)c(C)c2)c(=O)c1N=Nc1c(O)cc(c2ccccc12)S(O)(=O)=O |w:16.18| Show InChI InChI=1S/C22H20N4O5S/c1-12-8-9-15(10-13(12)2)26-22(28)20(14(3)25-26)23-24-21-17-7-5-4-6-16(17)19(11-18(21)27)32(29,30)31/h4-11,25,27H,1-3H3,(H,29,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	40	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cells				J Med Chem 44: 3730-45 (2001) BindingDB Entry DOI: 10.7270/Q2MP52KF
					More data for this Ligand-Target Pair
Thrombopoietin receptor (Homo sapiens (Human))	BDBM50105937 (3-Hydroxy-4-(10-hydroxy-phenanthren-9-ylazo)-napht...) Show SMILES Oc1cc(c2ccccc2c1N=Nc1c(O)c2ccccc2c2ccccc12)S(O)(=O)=O |w:12.14| Show InChI InChI=1S/C24H16N2O5S/c27-20-13-21(32(29,30)31)16-9-3-5-11-18(16)22(20)25-26-23-17-10-4-1-7-14(17)15-8-2-6-12-19(15)24(23)28/h1-13,27-28H,(H,29,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	200	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cells				J Med Chem 44: 3730-45 (2001) BindingDB Entry DOI: 10.7270/Q2MP52KF
					More data for this Ligand-Target Pair
Thrombopoietin receptor (Homo sapiens (Human))	BDBM50105939 (3-Hydroxy-4-[N'-(3-methyl-5-oxo-1-o-tolyl-1,5-dihy...) Show SMILES Cc1[nH]n(-c2ccccc2C)c(=O)c1N=Nc1c(O)cc(c2ccccc12)S(O)(=O)=O |w:15.17| Show InChI InChI=1S/C21H18N4O5S/c1-12-7-3-6-10-16(12)25-21(27)19(13(2)24-25)22-23-20-15-9-5-4-8-14(15)18(11-17(20)26)31(28,29)30/h3-11,24,26H,1-2H3,(H,28,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cells				J Med Chem 44: 3730-45 (2001) BindingDB Entry DOI: 10.7270/Q2MP52KF
					More data for this Ligand-Target Pair
Thrombopoietin receptor (Homo sapiens (Human))	BDBM50105940 (4-{N'-[1-(3,4-Dimethyl-phenyl)-5-oxo-1,5-dihydro-p...) Show SMILES Cc1ccc(cc1C)-n1[nH]cc(N=Nc2c(O)cc(c3ccccc23)S(O)(=O)=O)c1=O |w:13.14| Show InChI InChI=1S/C21H18N4O5S/c1-12-7-8-14(9-13(12)2)25-21(27)17(11-22-25)23-24-20-16-6-4-3-5-15(16)19(10-18(20)26)31(28,29)30/h3-11,22,26H,1-2H3,(H,28,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	100	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cells				J Med Chem 44: 3730-45 (2001) BindingDB Entry DOI: 10.7270/Q2MP52KF
					More data for this Ligand-Target Pair
Thrombopoietin receptor (Homo sapiens (Human))	BDBM50105942 (4-{N'-[1-(3-tert-Butyl-phenyl)-3-methyl-5-oxo-1,5-...) Show SMILES Cc1[nH]n(-c2cccc(c2)C(C)(C)C)c(=O)c1N=Nc1c(O)cc(c2ccccc12)S(O)(=O)=O |w:18.20| Show InChI InChI=1S/C24H24N4O5S/c1-14-21(23(30)28(27-14)16-9-7-8-15(12-16)24(2,3)4)25-26-22-18-11-6-5-10-17(18)20(13-19(22)29)34(31,32)33/h5-13,27,29H,1-4H3,(H,31,32,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	70	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cells				J Med Chem 44: 3730-45 (2001) BindingDB Entry DOI: 10.7270/Q2MP52KF
					More data for this Ligand-Target Pair
Thrombopoietin receptor (Homo sapiens (Human))	BDBM50105944 (3-Hydroxy-4-(2-hydroxy-5-methyl-phenylazo)-naphtha...) Show SMILES Cc1ccc(O)c(c1)N=Nc1c(O)cc(c2ccccc12)S(O)(=O)=O |w:8.8| Show InChI InChI=1S/C17H14N2O5S/c1-10-6-7-14(20)13(8-10)18-19-17-12-5-3-2-4-11(12)16(9-15(17)21)25(22,23)24/h2-9,20-21H,1H3,(H,22,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cells				J Med Chem 44: 3730-45 (2001) BindingDB Entry DOI: 10.7270/Q2MP52KF
					More data for this Ligand-Target Pair
Thrombopoietin receptor (Homo sapiens (Human))	BDBM50105941 (4-(2,3-Dihydroxy-naphthalen-1-ylazo)-3-hydroxy-nap...) Show SMILES Oc1cc(c2ccccc2c1N=Nc1c(O)c(O)cc2ccccc12)S(O)(=O)=O |w:12.14| Show InChI InChI=1S/C20H14N2O6S/c23-15-10-17(29(26,27)28)13-7-3-4-8-14(13)18(15)21-22-19-12-6-2-1-5-11(12)9-16(24)20(19)25/h1-10,23-25H,(H,26,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cells				J Med Chem 44: 3730-45 (2001) BindingDB Entry DOI: 10.7270/Q2MP52KF
					More data for this Ligand-Target Pair
Thrombopoietin receptor (Homo sapiens (Human))	BDBM50105943 (4-[N'-(1-Benzyl-3-methyl-5-oxo-1,5-dihydro-pyrazol...) Show SMILES Cc1[nH]n(Cc2ccccc2)c(=O)c1N=Nc1c(O)cc(c2ccccc12)S(O)(=O)=O |w:15.17| Show InChI InChI=1S/C21H18N4O5S/c1-13-19(21(27)25(24-13)12-14-7-3-2-4-8-14)22-23-20-16-10-6-5-9-15(16)18(11-17(20)26)31(28,29)30/h2-11,24,26H,12H2,1H3,(H,28,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cells				J Med Chem 44: 3730-45 (2001) BindingDB Entry DOI: 10.7270/Q2MP52KF
					More data for this Ligand-Target Pair
Thrombopoietin receptor (Homo sapiens (Human))	BDBM50105947 (3-Hydroxy-4-{N'-[3-methyl-5-oxo-1-(3-trifluorometh...) Show SMILES Cc1[nH]n(-c2cccc(c2)C(F)(F)F)c(=O)c1N=Nc1c(O)cc(c2ccccc12)S(O)(=O)=O |w:18.20| Show InChI InChI=1S/C21H15F3N4O5S/c1-11-18(20(30)28(27-11)13-6-4-5-12(9-13)21(22,23)24)25-26-19-15-8-3-2-7-14(15)17(10-16(19)29)34(31,32)33/h2-10,27,29H,1H3,(H,31,32,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	40	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cells				J Med Chem 44: 3730-45 (2001) BindingDB Entry DOI: 10.7270/Q2MP52KF
					More data for this Ligand-Target Pair
Thrombopoietin receptor (Homo sapiens (Human))	BDBM50105946 (4-{N'-[1-(3,4-Dimethyl-phenyl)-5-oxo-3-phenyl-1,5-...) Show SMILES Cc1ccc(cc1C)-n1[nH]c(c(N=Nc2c(O)cc(c3ccccc23)S(O)(=O)=O)c1=O)-c1ccccc1 |w:13.14| Show InChI InChI=1S/C27H22N4O5S/c1-16-12-13-19(14-17(16)2)31-27(33)26(24(30-31)18-8-4-3-5-9-18)29-28-25-21-11-7-6-10-20(21)23(15-22(25)32)37(34,35)36/h3-15,30,32H,1-2H3,(H,34,35,36)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	900	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cells				J Med Chem 44: 3730-45 (2001) BindingDB Entry DOI: 10.7270/Q2MP52KF
					More data for this Ligand-Target Pair
Thrombopoietin receptor (Homo sapiens (Human))	BDBM50105948 (4-{N'-[1-(3-Chloro-phenyl)-3-methyl-5-oxo-1,5-dihy...) Show SMILES Cc1[nH]n(-c2cccc(Cl)c2)c(=O)c1N=Nc1c(O)cc(c2ccccc12)S(O)(=O)=O |w:15.17| Show InChI InChI=1S/C20H15ClN4O5S/c1-11-18(20(27)25(24-11)13-6-4-5-12(21)9-13)22-23-19-15-8-3-2-7-14(15)17(10-16(19)26)31(28,29)30/h2-10,24,26H,1H3,(H,28,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cells				J Med Chem 44: 3730-45 (2001) BindingDB Entry DOI: 10.7270/Q2MP52KF
					More data for this Ligand-Target Pair
Thrombopoietin receptor (Homo sapiens (Human))	BDBM50105949 (4-(2,4-Dihydroxy-naphthalen-1-ylazo)-3-hydroxy-nap...) Show SMILES Oc1cc(O)c2ccccc2c1N=Nc1c(O)cc(c2ccccc12)S(O)(=O)=O |w:12.13| Show InChI InChI=1S/C20H14N2O6S/c23-15-9-16(24)19(13-7-3-1-5-11(13)15)21-22-20-14-8-4-2-6-12(14)18(10-17(20)25)29(26,27)28/h1-10,23-25H,(H,26,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cells				J Med Chem 44: 3730-45 (2001) BindingDB Entry DOI: 10.7270/Q2MP52KF
					More data for this Ligand-Target Pair
Thrombopoietin receptor (Homo sapiens (Human))	BDBM50105951 (4-(2,6-Dihydroxy-naphthalen-1-ylazo)-3-hydroxy-nap...) Show SMILES Oc1ccc2c(N=Nc3c(O)cc(c4ccccc34)S(O)(=O)=O)c(O)ccc2c1 |w:6.5| Show InChI InChI=1S/C20H14N2O6S/c23-12-6-7-13-11(9-12)5-8-16(24)19(13)21-22-20-15-4-2-1-3-14(15)18(10-17(20)25)29(26,27)28/h1-10,23-25H,(H,26,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cells				J Med Chem 44: 3730-45 (2001) BindingDB Entry DOI: 10.7270/Q2MP52KF
					More data for this Ligand-Target Pair
Thrombopoietin receptor (Homo sapiens (Human))	BDBM50105952 (4-{N'-[1-(4-Fluoro-phenyl)-3-methyl-5-oxo-1,5-dihy...) Show SMILES Cc1[nH]n(-c2ccc(F)cc2)c(=O)c1N=Nc1c(O)cc(c2ccccc12)S(O)(=O)=O |w:15.17| Show InChI InChI=1S/C20H15FN4O5S/c1-11-18(20(27)25(24-11)13-8-6-12(21)7-9-13)22-23-19-15-5-3-2-4-14(15)17(10-16(19)26)31(28,29)30/h2-10,24,26H,1H3,(H,28,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	500	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cells				J Med Chem 44: 3730-45 (2001) BindingDB Entry DOI: 10.7270/Q2MP52KF
					More data for this Ligand-Target Pair
Thrombopoietin receptor (Homo sapiens (Human))	BDBM50105945 (3-Hydroxy-4-[N'-(3-methyl-5-oxo-1-p-tolyl-1,5-dihy...) Show SMILES Cc1[nH]n(-c2ccc(C)cc2)c(=O)c1N=Nc1c(O)cc(c2ccccc12)S(O)(=O)=O |w:15.17| Show InChI InChI=1S/C21H18N4O5S/c1-12-7-9-14(10-8-12)25-21(27)19(13(2)24-25)22-23-20-16-6-4-3-5-15(16)18(11-17(20)26)31(28,29)30/h3-11,24,26H,1-2H3,(H,28,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cells				J Med Chem 44: 3730-45 (2001) BindingDB Entry DOI: 10.7270/Q2MP52KF
					More data for this Ligand-Target Pair
Thrombopoietin receptor (Homo sapiens (Human))	BDBM50105956 (3-Hydroxy-4-(2-hydroxy-4-sulfo-naphthalen-1-ylazo)...) Show SMILES OC(=O)c1cc2ccccc2c(N=Nc2c(O)cc(c3ccccc23)S(O)(=O)=O)c1O |w:12.12| Show InChI InChI=1S/C21H14N2O7S/c24-16-10-17(31(28,29)30)13-7-3-4-8-14(13)18(16)22-23-19-12-6-2-1-5-11(12)9-15(20(19)25)21(26)27/h1-10,24-25H,(H,26,27)(H,28,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cells				J Med Chem 44: 3730-45 (2001) BindingDB Entry DOI: 10.7270/Q2MP52KF
					More data for this Ligand-Target Pair
Thrombopoietin receptor (Homo sapiens (Human))	BDBM50105953 (4-(2,7-Dihydroxy-naphthalen-1-ylazo)-3-hydroxy-nap...) Show SMILES Oc1ccc2ccc(O)c(N=Nc3c(O)cc(c4ccccc34)S(O)(=O)=O)c2c1 |w:10.9| Show InChI InChI=1S/C20H14N2O6S/c23-12-7-5-11-6-8-16(24)20(15(11)9-12)22-21-19-14-4-2-1-3-13(14)18(10-17(19)25)29(26,27)28/h1-10,23-25H,(H,26,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cells				J Med Chem 44: 3730-45 (2001) BindingDB Entry DOI: 10.7270/Q2MP52KF
					More data for this Ligand-Target Pair
Thrombopoietin receptor (Homo sapiens (Human))	BDBM50105955 (3-Hydroxy-4-{N'-[3-methyl-1-(2-nitro-phenyl)-5-oxo...) Show SMILES Cc1[nH]n(-c2ccccc2[N+]([O-])=O)c(=O)c1N=Nc1c(O)cc(c2ccccc12)S(O)(=O)=O |w:17.19| Show InChI InChI=1S/C20H15N5O7S/c1-11-18(20(27)24(23-11)14-8-4-5-9-15(14)25(28)29)21-22-19-13-7-3-2-6-12(13)17(10-16(19)26)33(30,31)32/h2-10,23,26H,1H3,(H,30,31,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cells				J Med Chem 44: 3730-45 (2001) BindingDB Entry DOI: 10.7270/Q2MP52KF
					More data for this Ligand-Target Pair
Thrombopoietin receptor (Homo sapiens (Human))	BDBM50105954 (1-(4-tert-Butyl-phenyl)-4-[(2-hydroxy-4-sulfo-naph...) Show SMILES CC(C)(C)OC(=O)c1[nH]n(-c2ccc(cc2)C(C)(C)C)c(=O)c1N=Nc1c(O)cc(c2ccccc12)S(O)(=O)=O |w:24.26| Show InChI InChI=1S/C28H30N4O7S/c1-27(2,3)16-11-13-17(14-12-16)32-25(34)23(24(31-32)26(35)39-28(4,5)6)30-29-22-19-10-8-7-9-18(19)21(15-20(22)33)40(36,37)38/h7-15,31,33H,1-6H3,(H,36,37,38)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	200	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cells				J Med Chem 44: 3730-45 (2001) BindingDB Entry DOI: 10.7270/Q2MP52KF
					More data for this Ligand-Target Pair
Thrombopoietin receptor (Homo sapiens (Human))	BDBM50105959 (3-Hydroxy-4-{N'-[3-methyl-1-(4-nitro-phenyl)-5-oxo...) Show SMILES Cc1[nH]n(-c2ccc(cc2)[N+]([O-])=O)c(=O)c1N=Nc1c(O)cc(c2ccccc12)S(O)(=O)=O |w:17.19| Show InChI InChI=1S/C20H15N5O7S/c1-11-18(20(27)24(23-11)12-6-8-13(9-7-12)25(28)29)21-22-19-15-5-3-2-4-14(15)17(10-16(19)26)33(30,31)32/h2-10,23,26H,1H3,(H,30,31,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	400	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cells				J Med Chem 44: 3730-45 (2001) BindingDB Entry DOI: 10.7270/Q2MP52KF
					More data for this Ligand-Target Pair
Thrombopoietin receptor (Homo sapiens (Human))	BDBM50105958 (3-Hydroxy-4-[N'-(3-methyl-5-oxo-1-p-tolyl-1,5-dihy...) Show SMILES Cc1[nH]n(-c2ccc(C)cc2)c(=O)c1N=Nc1c(O)cc(C(O)=O)c2ccccc12 |w:15.17| Show InChI InChI=1S/C22H18N4O4/c1-12-7-9-14(10-8-12)26-21(28)19(13(2)25-26)23-24-20-16-6-4-3-5-15(16)17(22(29)30)11-18(20)27/h3-11,25,27H,1-2H3,(H,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cells				J Med Chem 44: 3730-45 (2001) BindingDB Entry DOI: 10.7270/Q2MP52KF
					More data for this Ligand-Target Pair
Thrombopoietin receptor (Homo sapiens (Human))	BDBM50105950 (4-{N'-[1-(3,4-Dichloro-phenyl)-3-methyl-5-oxo-1,5-...) Show SMILES Cc1[nH]n(-c2ccc(Cl)c(Cl)c2)c(=O)c1N=Nc1c(O)cc(c2ccccc12)S(O)(=O)=O |w:16.18| Show InChI InChI=1S/C20H14Cl2N4O5S/c1-10-18(20(28)26(25-10)11-6-7-14(21)15(22)8-11)23-24-19-13-5-3-2-4-12(13)17(9-16(19)27)32(29,30)31/h2-9,25,27H,1H3,(H,29,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	200	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cells				J Med Chem 44: 3730-45 (2001) BindingDB Entry DOI: 10.7270/Q2MP52KF
					More data for this Ligand-Target Pair
Thrombopoietin receptor (Homo sapiens (Human))	BDBM50105957 (4-{N'-[3-Amino-1-(4-tert-butyl-phenyl)-5-oxo-1,5-d...) Show SMILES CC(C)(C)c1ccc(cc1)-n1[nH]c(N)c(N=Nc2c(O)cc(c3ccccc23)S(O)(=O)=O)c1=O |w:16.17| Show InChI InChI=1S/C23H23N5O5S/c1-23(2,3)13-8-10-14(11-9-13)28-22(30)20(21(24)27-28)26-25-19-16-7-5-4-6-15(16)18(12-17(19)29)34(31,32)33/h4-12,27,29H,24H2,1-3H3,(H,31,32,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cells				J Med Chem 44: 3730-45 (2001) BindingDB Entry DOI: 10.7270/Q2MP52KF
					More data for this Ligand-Target Pair
Thrombopoietin receptor (Homo sapiens (Human))	BDBM50105962 (3-Hydroxy-4-{N'-[1-(4-isopropyl-phenyl)-3-methyl-5...) Show SMILES CC(C)c1ccc(cc1)-n1[nH]c(C)c(N=Nc2c(O)cc(c3ccccc23)S(O)(=O)=O)c1=O |w:15.16| Show InChI InChI=1S/C23H22N4O5S/c1-13(2)15-8-10-16(11-9-15)27-23(29)21(14(3)26-27)24-25-22-18-7-5-4-6-17(18)20(12-19(22)28)33(30,31)32/h4-13,26,28H,1-3H3,(H,30,31,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	70	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cells				J Med Chem 44: 3730-45 (2001) BindingDB Entry DOI: 10.7270/Q2MP52KF
					More data for this Ligand-Target Pair
Thrombopoietin receptor (Homo sapiens (Human))	BDBM50105960 (3-Hydroxy-4-[N'-(3-methyl-5-oxo-1-m-tolyl-1,5-dihy...) Show SMILES Cc1[nH]n(-c2cccc(C)c2)c(=O)c1N=Nc1c(O)cc(c2ccccc12)S(O)(=O)=O |w:15.17| Show InChI InChI=1S/C21H18N4O5S/c1-12-6-5-7-14(10-12)25-21(27)19(13(2)24-25)22-23-20-16-9-4-3-8-15(16)18(11-17(20)26)31(28,29)30/h3-11,24,26H,1-2H3,(H,28,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	700	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cells				J Med Chem 44: 3730-45 (2001) BindingDB Entry DOI: 10.7270/Q2MP52KF
					More data for this Ligand-Target Pair
Thrombopoietin receptor (Homo sapiens (Human))	BDBM50105961 (3-Hydroxy-4-(2-hydroxy-7-methoxy-naphthalen-1-ylaz...) Show SMILES COc1ccc2ccc(O)c(N=Nc3c(O)cc(c4ccccc34)S(O)(=O)=O)c2c1 |w:11.10| Show InChI InChI=1S/C21H16N2O6S/c1-29-13-8-6-12-7-9-17(24)21(16(12)10-13)23-22-20-15-5-3-2-4-14(15)19(11-18(20)25)30(26,27)28/h2-11,24-25H,1H3,(H,26,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	300	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cells				J Med Chem 44: 3730-45 (2001) BindingDB Entry DOI: 10.7270/Q2MP52KF
					More data for this Ligand-Target Pair
Thrombopoietin receptor (Homo sapiens (Human))	BDBM50105964 (3-Hydroxy-4-[N'-(3-methyl-5-oxo-1-pyridin-2-yl-1,5...) Show SMILES Cc1[nH]n(-c2ccccn2)c(=O)c1N=Nc1c(O)cc(c2ccccc12)S(O)(=O)=O |w:14.16| Show InChI InChI=1S/C19H15N5O5S/c1-11-17(19(26)24(23-11)16-8-4-5-9-20-16)21-22-18-13-7-3-2-6-12(13)15(10-14(18)25)30(27,28)29/h2-10,23,25H,1H3,(H,27,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cells				J Med Chem 44: 3730-45 (2001) BindingDB Entry DOI: 10.7270/Q2MP52KF
					More data for this Ligand-Target Pair
Thrombopoietin receptor (Homo sapiens (Human))	BDBM50105967 (3-Hydroxy-4-{N'-[1-(4-iodo-phenyl)-3-methyl-5-oxo-...) Show SMILES Cc1[nH]n(-c2ccc(I)cc2)c(=O)c1N=Nc1c(O)cc(c2ccccc12)S(O)(=O)=O |w:15.17| Show InChI InChI=1S/C20H15IN4O5S/c1-11-18(20(27)25(24-11)13-8-6-12(21)7-9-13)22-23-19-15-5-3-2-4-14(15)17(10-16(19)26)31(28,29)30/h2-10,24,26H,1H3,(H,28,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	300	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cells				J Med Chem 44: 3730-45 (2001) BindingDB Entry DOI: 10.7270/Q2MP52KF
					More data for this Ligand-Target Pair
Thrombopoietin receptor (Homo sapiens (Human))	BDBM50105965 (4-{N'-[1-(3,4-Dimethyl-phenyl)-3-methyl-5-oxo-1,5-...) Show SMILES Cc1[nH]n(-c2ccc(C)c(C)c2)c(=O)c1N=Nc1c(O)cc(C(O)=O)c2ccccc12 |w:16.18| Show InChI InChI=1S/C23H20N4O4/c1-12-8-9-15(10-13(12)2)27-22(29)20(14(3)26-27)24-25-21-17-7-5-4-6-16(17)18(23(30)31)11-19(21)28/h4-11,26,28H,1-3H3,(H,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cells				J Med Chem 44: 3730-45 (2001) BindingDB Entry DOI: 10.7270/Q2MP52KF
					More data for this Ligand-Target Pair
Thrombopoietin receptor (Homo sapiens (Human))	BDBM50105966 (3-Hydroxy-4-{N'-[3-methyl-5-oxo-1-(4-trifluorometh...) Show SMILES Cc1[nH]n(-c2ccc(cc2)C(F)(F)F)c(=O)c1N=Nc1c(O)cc(c2ccccc12)S(O)(=O)=O |w:18.20| Show InChI InChI=1S/C21H15F3N4O5S/c1-11-18(20(30)28(27-11)13-8-6-12(7-9-13)21(22,23)24)25-26-19-15-5-3-2-4-14(15)17(10-16(19)29)34(31,32)33/h2-10,27,29H,1H3,(H,31,32,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	100	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cells				J Med Chem 44: 3730-45 (2001) BindingDB Entry DOI: 10.7270/Q2MP52KF
					More data for this Ligand-Target Pair
Thrombopoietin receptor (Homo sapiens (Human))	BDBM50105968 (4-{N'-[1-(4-Chloro-phenyl)-3-methyl-5-oxo-1,5-dihy...) Show SMILES Cc1[nH]n(-c2ccc(Cl)cc2)c(=O)c1N=Nc1c(O)cc(c2ccccc12)S(O)(=O)=O |w:15.17| Show InChI InChI=1S/C20H15ClN4O5S/c1-11-18(20(27)25(24-11)13-8-6-12(21)7-9-13)22-23-19-15-5-3-2-4-14(15)17(10-16(19)26)31(28,29)30/h2-10,24,26H,1H3,(H,28,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cells				J Med Chem 44: 3730-45 (2001) BindingDB Entry DOI: 10.7270/Q2MP52KF
					More data for this Ligand-Target Pair
Thrombopoietin receptor (Homo sapiens (Human))	BDBM50105969 (4-{N'-[1-(4-Benzyloxy-phenyl)-3-methyl-5-oxo-1,5-d...) Show SMILES Cc1[nH]n(-c2ccc(OCc3ccccc3)cc2)c(=O)c1N=Nc1c(O)cc(c2ccccc12)S(O)(=O)=O |w:22.25| Show InChI InChI=1S/C27H22N4O6S/c1-17-25(28-29-26-22-10-6-5-9-21(22)24(15-23(26)32)38(34,35)36)27(33)31(30-17)19-11-13-20(14-12-19)37-16-18-7-3-2-4-8-18/h2-15,30,32H,16H2,1H3,(H,34,35,36)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	200	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cells				J Med Chem 44: 3730-45 (2001) BindingDB Entry DOI: 10.7270/Q2MP52KF
					More data for this Ligand-Target Pair
Thrombopoietin receptor (Homo sapiens (Human))	BDBM50105972 (3-Hydroxy-4-{N'-[3-methyl-1-(3-nitro-phenyl)-5-oxo...) Show SMILES Cc1[nH]n(-c2cccc(c2)[N+]([O-])=O)c(=O)c1N=Nc1c(O)cc(c2ccccc12)S(O)(=O)=O |w:17.19| Show InChI InChI=1S/C20H15N5O7S/c1-11-18(20(27)24(23-11)12-5-4-6-13(9-12)25(28)29)21-22-19-15-8-3-2-7-14(15)17(10-16(19)26)33(30,31)32/h2-10,23,26H,1H3,(H,30,31,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	300	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cells				J Med Chem 44: 3730-45 (2001) BindingDB Entry DOI: 10.7270/Q2MP52KF
					More data for this Ligand-Target Pair
Thrombopoietin receptor (Homo sapiens (Human))	BDBM50105973 (4-{N'-[3-tert-Butyl-1-(3,4-dimethyl-phenyl)-5-oxo-...) Show SMILES Cc1ccc(cc1C)-n1[nH]c(c(N=Nc2c(O)cc(c3ccccc23)S(O)(=O)=O)c1=O)C(C)(C)C |w:13.14| Show InChI InChI=1S/C25H26N4O5S/c1-14-10-11-16(12-15(14)2)29-24(31)22(23(28-29)25(3,4)5)27-26-21-18-9-7-6-8-17(18)20(13-19(21)30)35(32,33)34/h6-13,28,30H,1-5H3,(H,32,33,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	300	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cells				J Med Chem 44: 3730-45 (2001) BindingDB Entry DOI: 10.7270/Q2MP52KF
					More data for this Ligand-Target Pair
Thrombopoietin receptor (Homo sapiens (Human))	BDBM50105970 (4-{N'-[1-(4-tert-Butyl-phenyl)-3-methyl-5-oxo-1,5-...) Show SMILES Cc1[nH]n(-c2ccc(cc2)C(C)(C)C)c(=O)c1N=Nc1c(O)cc(c2ccccc12)S(O)(=O)=O |w:18.20| Show InChI InChI=1S/C24H24N4O5S/c1-14-21(23(30)28(27-14)16-11-9-15(10-12-16)24(2,3)4)25-26-22-18-8-6-5-7-17(18)20(13-19(22)29)34(31,32)33/h5-13,27,29H,1-4H3,(H,31,32,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	20	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cells				J Med Chem 44: 3730-45 (2001) BindingDB Entry DOI: 10.7270/Q2MP52KF
					More data for this Ligand-Target Pair
Thrombopoietin receptor (Homo sapiens (Human))	BDBM50105971 (4-{N'-[1-(2-Chloro-phenyl)-3-methyl-5-oxo-1,5-dihy...) Show SMILES Cc1[nH]n(-c2ccccc2Cl)c(=O)c1N=Nc1c(O)cc(c2ccccc12)S(O)(=O)=O |w:15.17| Show InChI InChI=1S/C20H15ClN4O5S/c1-11-18(20(27)25(24-11)15-9-5-4-8-14(15)21)22-23-19-13-7-3-2-6-12(13)17(10-16(19)26)31(28,29)30/h2-10,24,26H,1H3,(H,28,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cells				J Med Chem 44: 3730-45 (2001) BindingDB Entry DOI: 10.7270/Q2MP52KF
					More data for this Ligand-Target Pair
Thrombopoietin receptor (Homo sapiens (Human))	BDBM50105976 (3-Hydroxy-4-(1-hydroxy-naphthalen-2-ylazo)-naphtha...) Show SMILES Oc1cc(c2ccccc2c1N=Nc1ccc2ccccc2c1O)S(O)(=O)=O |w:12.14| Show InChI InChI=1S/C20H14N2O5S/c23-17-11-18(28(25,26)27)14-7-3-4-8-15(14)19(17)22-21-16-10-9-12-5-1-2-6-13(12)20(16)24/h1-11,23-24H,(H,25,26,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	70	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cells				J Med Chem 44: 3730-45 (2001) BindingDB Entry DOI: 10.7270/Q2MP52KF
					More data for this Ligand-Target Pair
Thrombopoietin receptor (Homo sapiens (Human))	BDBM50105974 (3-Hydroxy-4-(4-hydroxy-2-methoxy-naphthalen-1-ylaz...) Show SMILES COc1cc(O)c2ccccc2c1N=Nc1c(O)cc(c2ccccc12)S(O)(=O)=O |w:13.14| Show InChI InChI=1S/C21H16N2O6S/c1-29-18-10-16(24)12-6-2-4-8-14(12)21(18)23-22-20-15-9-5-3-7-13(15)19(11-17(20)25)30(26,27)28/h2-11,24-25H,1H3,(H,26,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cells				J Med Chem 44: 3730-45 (2001) BindingDB Entry DOI: 10.7270/Q2MP52KF
					More data for this Ligand-Target Pair
Thrombopoietin receptor (Homo sapiens (Human))	BDBM50105975 (3-Hydroxy-4-{N'-[1-(4-methanesulfonyl-phenyl)-3-me...) Show SMILES Cc1[nH]n(-c2ccc(cc2)S(C)(=O)=O)c(=O)c1N=Nc1c(O)cc(c2ccccc12)S(O)(=O)=O |w:18.20| Show InChI InChI=1S/C21H18N4O7S2/c1-12-19(21(27)25(24-12)13-7-9-14(10-8-13)33(2,28)29)22-23-20-16-6-4-3-5-15(16)18(11-17(20)26)34(30,31)32/h3-11,24,26H,1-2H3,(H,30,31,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cells				J Med Chem 44: 3730-45 (2001) BindingDB Entry DOI: 10.7270/Q2MP52KF
					More data for this Ligand-Target Pair
Thrombopoietin receptor (Homo sapiens (Human))	BDBM50105977 (3-Hydroxy-4-(2-hydroxy-naphthalen-1-ylazo)-naphtha...) Show SMILES Oc1ccc2ccccc2c1N=Nc1c(O)cc(c2ccccc12)S(O)(=O)=O |w:11.12| Show InChI InChI=1S/C20H14N2O5S/c23-16-10-9-12-5-1-2-6-13(12)19(16)21-22-20-15-8-4-3-7-14(15)18(11-17(20)24)28(25,26)27/h1-11,23-24H,(H,25,26,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	200	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cells				J Med Chem 44: 3730-45 (2001) BindingDB Entry DOI: 10.7270/Q2MP52KF
					More data for this Ligand-Target Pair
Thrombopoietin receptor (Homo sapiens (Human))	BDBM50105978 (4-{N'-[1-(3-Ethylsulfamoyl-phenyl)-3-methyl-5-oxo-...) Show SMILES CCNS(=O)(=O)c1cccc(c1)-n1[nH]c(C)c(N=Nc2c(O)cc(c3ccccc23)S(O)(=O)=O)c1=O |w:18.19| Show InChI InChI=1S/C22H21N5O7S2/c1-3-23-35(30,31)15-8-6-7-14(11-15)27-22(29)20(13(2)26-27)24-25-21-17-10-5-4-9-16(17)19(12-18(21)28)36(32,33)34/h4-12,23,26,28H,3H2,1-2H3,(H,32,33,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cells				J Med Chem 44: 3730-45 (2001) BindingDB Entry DOI: 10.7270/Q2MP52KF
					More data for this Ligand-Target Pair
Thrombopoietin receptor (Homo sapiens (Human))	BDBM50105979 (1-(4-tert-Butyl-phenyl)-4-[(2-hydroxy-4-sulfo-naph...) Show SMILES CCOC(=O)c1[nH]n(-c2ccc(cc2)C(C)(C)C)c(=O)c1N=Nc1c(O)cc(c2ccccc12)S(O)(=O)=O |w:22.24| Show InChI InChI=1S/C26H26N4O7S/c1-5-37-25(33)23-22(24(32)30(29-23)16-12-10-15(11-13-16)26(2,3)4)28-27-21-18-9-7-6-8-17(18)20(14-19(21)31)38(34,35)36/h6-14,29,31H,5H2,1-4H3,(H,34,35,36)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cells				J Med Chem 44: 3730-45 (2001) BindingDB Entry DOI: 10.7270/Q2MP52KF
					More data for this Ligand-Target Pair
Thrombopoietin receptor (Homo sapiens (Human))	BDBM50105980 (3-Hydroxy-4-[N'-(3-methyl-5-oxo-1-phenyl-1,5-dihyd...) Show SMILES Cc1[nH]n(-c2ccccc2)c(=O)c1N=Nc1c(O)cc(C(O)=O)c2ccccc12 |w:14.16| Show InChI InChI=1S/C21H16N4O4/c1-12-18(20(27)25(24-12)13-7-3-2-4-8-13)22-23-19-15-10-6-5-9-14(15)16(21(28)29)11-17(19)26/h2-11,24,26H,1H3,(H,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cells				J Med Chem 44: 3730-45 (2001) BindingDB Entry DOI: 10.7270/Q2MP52KF
					More data for this Ligand-Target Pair
Thrombopoietin receptor (Homo sapiens (Human))	BDBM50105936 (3-Hydroxy-4-[N'-(3-methyl-5-oxo-1-phenyl-1,5-dihyd...) Show SMILES Cc1[nH]n(-c2ccccc2)c(=O)c1N=Nc1c(O)cc(c2ccccc12)S(O)(=O)=O |w:14.16| Show InChI InChI=1S/C20H16N4O5S/c1-12-18(20(26)24(23-12)13-7-3-2-4-8-13)21-22-19-15-10-6-5-9-14(15)17(11-16(19)25)30(27,28)29/h2-11,23,25H,1H3,(H,27,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cells				J Med Chem 44: 3730-45 (2001) BindingDB Entry DOI: 10.7270/Q2MP52KF
					More data for this Ligand-Target Pair