Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Solute carrier family 15 member 1 (Homo sapiens (Human)) | BDBM50139892 ((S)-2-((S)-2-Amino-3-phenyl-propionylamino)-propio...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | 180 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Tromsø Curated by ChEMBL | Assay Description Affinity fo the compound against human Intestinal peptide transporter PepT1 in Caco-2 cells was measured as inhibition of [14C]-Gly-Sar uptake | J Med Chem 47: 1060-9 (2004) Article DOI: 10.1021/jm031022+ BindingDB Entry DOI: 10.7270/Q2DF6QMV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 15 member 1 (Homo sapiens (Human)) | BDBM50139894 (((S)-2-Amino-3-phenyl-propionylamino)-acetic acid ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Tromsø Curated by ChEMBL | Assay Description Affinity fo the compound against human Intestinal peptide transporter PepT1 in Caco-2 cells was measured as inhibition of [14C]-Gly-Sar uptake | J Med Chem 47: 1060-9 (2004) Article DOI: 10.1021/jm031022+ BindingDB Entry DOI: 10.7270/Q2DF6QMV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 15 member 1 (Homo sapiens (Human)) | BDBM50139890 ((S)-5-Amino-4-oxo-6-phenyl-hexanoic acid | CHEMBL1...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Tromsø Curated by ChEMBL | Assay Description Affinity fo the compound against human Intestinal peptide transporter PepT1 in Caco-2 cells was measured as inhibition of [14C]-Gly-Sar uptake | J Med Chem 47: 1060-9 (2004) Article DOI: 10.1021/jm031022+ BindingDB Entry DOI: 10.7270/Q2DF6QMV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 15 member 1 (Homo sapiens (Human)) | BDBM50152064 (2-(3-Amino-4-methyl-2-oxo-pentyl)-succinic acid 4-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Tromsø Curated by ChEMBL | Assay Description Affinity for hPEPT1 in mature Caco-2 cell monolayers using [14C]-Gly-Sar | J Med Chem 47: 4755-65 (2004) Article DOI: 10.1021/jm040780c BindingDB Entry DOI: 10.7270/Q2WM1CWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 15 member 1 (Homo sapiens (Human)) | BDBM50139893 ((E)-(S)-5-Amino-4-(S)-hydroxy-6-phenyl-hex-2-enoic...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.98E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Tromsø Curated by ChEMBL | Assay Description Affinity fo the compound against human Intestinal peptide transporter PepT1 in Caco-2 cells was measured as inhibition of [14C]-Gly-Sar uptake | J Med Chem 47: 1060-9 (2004) Article DOI: 10.1021/jm031022+ BindingDB Entry DOI: 10.7270/Q2DF6QMV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 15 member 1 (Homo sapiens (Human)) | BDBM50152062 (2-(3-Amino-2-oxo-4-phenyl-butyl)-succinic acid 4-b...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 6.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Tromsø Curated by ChEMBL | Assay Description Affinity for hPEPT1 in mature Caco-2 cell monolayers using [14C]-Gly-Sar | J Med Chem 47: 4755-65 (2004) Article DOI: 10.1021/jm040780c BindingDB Entry DOI: 10.7270/Q2WM1CWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 15 member 1 (Homo sapiens (Human)) | BDBM50152063 (5-Amino-6-methyl-4-oxo-heptanoic acid benzyl ester...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.33E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Tromsø Curated by ChEMBL | Assay Description Affinity for hPEPT1 in mature Caco-2 cell monolayers using [14C]-Gly-Sar | J Med Chem 47: 4755-65 (2004) Article DOI: 10.1021/jm040780c BindingDB Entry DOI: 10.7270/Q2WM1CWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 15 member 1 (Homo sapiens (Human)) | BDBM50420184 (CHEMBL2074601) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | 2.10E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Royal Danish School of Pharmacy Curated by ChEMBL | Assay Description TP_TRANSPORTER: inhibition of Gly-Sar uptake in Caco-2 cells | J Control Release 86: 279-92 (2003) BindingDB Entry DOI: 10.7270/Q27H1KVK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 15 member 1 (Homo sapiens (Human)) | BDBM50420183 (CHEMBL1823468) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | 2.80E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Royal Danish School of Pharmacy Curated by ChEMBL | Assay Description TP_TRANSPORTER: inhibition of Gly-Sar uptake in Caco-2 cells | J Control Release 86: 279-92 (2003) BindingDB Entry DOI: 10.7270/Q27H1KVK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 15 member 1 (Homo sapiens (Human)) | BDBM50152065 (3-Amino-4-oxo-heptanedioic acid 1-benzyl ester | C...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 4.17E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Tromsø Curated by ChEMBL | Assay Description Affinity for hPEPT1 in mature Caco-2 cell monolayers using [14C]-Gly-Sar | J Med Chem 47: 4755-65 (2004) Article DOI: 10.1021/jm040780c BindingDB Entry DOI: 10.7270/Q2WM1CWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 15 member 1 (Homo sapiens (Human)) | BDBM50152066 (5-Amino-4-oxo-6-phenyl-hexanoic acid benzyl ester ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 9.05E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Tromsø Curated by ChEMBL | Assay Description Affinity for hPEPT1 in mature Caco-2 cell monolayers using [14C]-Gly-Sar | J Med Chem 47: 4755-65 (2004) Article DOI: 10.1021/jm040780c BindingDB Entry DOI: 10.7270/Q2WM1CWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 15 member 1 (Homo sapiens (Human)) | BDBM50418932 (CHEMBL1807354) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 4.68E+7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Biogen Idec Inc. Curated by ChEMBL | Assay Description Binding affinity to PEPT1 in human Caco2 cells assessed as inhibition of [14C]Gly-Sar apical uptake after 5 mins by liquid scintillation counting | Bioorg Med Chem Lett 21: 4597-601 (2011) Article DOI: 10.1016/j.bmcl.2011.05.108 BindingDB Entry DOI: 10.7270/Q2VM4DHS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 15 member 1 (Homo sapiens (Human)) | BDBM50418933 (CHEMBL1807356) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 1.23E+8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Biogen Idec Inc. Curated by ChEMBL | Assay Description Binding affinity to PEPT1 in human Caco2 cells assessed as inhibition of [14C]Gly-Sar apical uptake after 5 mins by liquid scintillation counting | Bioorg Med Chem Lett 21: 4597-601 (2011) Article DOI: 10.1016/j.bmcl.2011.05.108 BindingDB Entry DOI: 10.7270/Q2VM4DHS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 15 member 1 (Homo sapiens (Human)) | BDBM50418934 (CHEMBL1807357) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 2.45E+8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Biogen Idec Inc. Curated by ChEMBL | Assay Description Binding affinity to PEPT1 in human Caco2 cells assessed as inhibition of [14C]Gly-Sar apical uptake after 5 mins by liquid scintillation counting | Bioorg Med Chem Lett 21: 4597-601 (2011) Article DOI: 10.1016/j.bmcl.2011.05.108 BindingDB Entry DOI: 10.7270/Q2VM4DHS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 15 member 1 (Homo sapiens (Human)) | BDBM50418935 (CHEMBL1807353) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.51E+8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Biogen Idec Inc. Curated by ChEMBL | Assay Description Binding affinity to PEPT1 in human Caco2 cells assessed as inhibition of [14C]Gly-Sar apical uptake after 5 mins by liquid scintillation counting | Bioorg Med Chem Lett 21: 4597-601 (2011) Article DOI: 10.1016/j.bmcl.2011.05.108 BindingDB Entry DOI: 10.7270/Q2VM4DHS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 15 member 1 (Homo sapiens (Human)) | BDBM50418931 (CHEMBL1807351) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 2.57E+8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Biogen Idec Inc. Curated by ChEMBL | Assay Description Binding affinity to PEPT1 in human Caco2 cells assessed as inhibition of [14C]Gly-Sar apical uptake after 5 mins by liquid scintillation counting | Bioorg Med Chem Lett 21: 4597-601 (2011) Article DOI: 10.1016/j.bmcl.2011.05.108 BindingDB Entry DOI: 10.7270/Q2VM4DHS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 15 member 1 (Homo sapiens (Human)) | BDBM50418936 (CHEMBL1807352) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.24E+8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Biogen Idec Inc. Curated by ChEMBL | Assay Description Binding affinity to PEPT1 in human Caco2 cells assessed as inhibition of [14C]Gly-Sar apical uptake after 5 mins by liquid scintillation counting | Bioorg Med Chem Lett 21: 4597-601 (2011) Article DOI: 10.1016/j.bmcl.2011.05.108 BindingDB Entry DOI: 10.7270/Q2VM4DHS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 15 member 1 (Homo sapiens (Human)) | BDBM50139892 ((S)-2-((S)-2-Amino-3-phenyl-propionylamino)-propio...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Tromsø Curated by ChEMBL | Assay Description Concentration required to inhibit the maximum [14C]-Gly-Sar uptake by human Intestinal peptide transporter PepT1 in Caco-2 cells | J Med Chem 47: 1060-9 (2004) Article DOI: 10.1021/jm031022+ BindingDB Entry DOI: 10.7270/Q2DF6QMV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 15 member 1 (Homo sapiens (Human)) | BDBM50139894 (((S)-2-Amino-3-phenyl-propionylamino)-acetic acid ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Tromsø Curated by ChEMBL | Assay Description Concentration required to inhibit the maximum [14C]-Gly-Sar uptake by human Intestinal peptide transporter PepT1 in Caco-2 cells | J Med Chem 47: 1060-9 (2004) Article DOI: 10.1021/jm031022+ BindingDB Entry DOI: 10.7270/Q2DF6QMV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 15 member 1 (Homo sapiens (Human)) | BDBM50139890 ((S)-5-Amino-4-oxo-6-phenyl-hexanoic acid | CHEMBL1...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Tromsø Curated by ChEMBL | Assay Description Concentration required to inhibit the maximum [14C]-Gly-Sar uptake by human Intestinal peptide transporter PepT1 in Caco-2 cells | J Med Chem 47: 1060-9 (2004) Article DOI: 10.1021/jm031022+ BindingDB Entry DOI: 10.7270/Q2DF6QMV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 15 member 1 (Homo sapiens (Human)) | BDBM50152064 (2-(3-Amino-4-methyl-2-oxo-pentyl)-succinic acid 4-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Tromsø Curated by ChEMBL | Assay Description Inhibition of [14C]-Gly-Sar transport by hPEPT1 in Caco-2 cell monolayers | J Med Chem 47: 4755-65 (2004) Article DOI: 10.1021/jm040780c BindingDB Entry DOI: 10.7270/Q2WM1CWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 15 member 1 (Homo sapiens (Human)) | BDBM50139893 ((E)-(S)-5-Amino-4-(S)-hydroxy-6-phenyl-hex-2-enoic...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.05E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Tromsø Curated by ChEMBL | Assay Description Concentration required to inhibit the maximum [14C]-Gly-Sar uptake by human Intestinal peptide transporter PepT1 in Caco-2 cells | J Med Chem 47: 1060-9 (2004) Article DOI: 10.1021/jm031022+ BindingDB Entry DOI: 10.7270/Q2DF6QMV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 15 member 1 (Homo sapiens (Human)) | BDBM50152062 (2-(3-Amino-2-oxo-4-phenyl-butyl)-succinic acid 4-b...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Tromsø Curated by ChEMBL | Assay Description Inhibition of [14C]-Gly-Sar transport by hPEPT1 in Caco-2 cell monolayers | J Med Chem 47: 4755-65 (2004) Article DOI: 10.1021/jm040780c BindingDB Entry DOI: 10.7270/Q2WM1CWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 15 member 1 (Homo sapiens (Human)) | BDBM50152063 (5-Amino-6-methyl-4-oxo-heptanoic acid benzyl ester...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.34E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Tromsø Curated by ChEMBL | Assay Description Inhibition of [14C]-Gly-Sar transport by hPEPT1 in Caco-2 cell monolayers | J Med Chem 47: 4755-65 (2004) Article DOI: 10.1021/jm040780c BindingDB Entry DOI: 10.7270/Q2WM1CWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 15 member 1 (Homo sapiens (Human)) | BDBM50152065 (3-Amino-4-oxo-heptanedioic acid 1-benzyl ester | C...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.22E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Tromsø Curated by ChEMBL | Assay Description Inhibition of [14C]-Gly-Sar transport by hPEPT1 in Caco-2 cell monolayers | J Med Chem 47: 4755-65 (2004) Article DOI: 10.1021/jm040780c BindingDB Entry DOI: 10.7270/Q2WM1CWG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 15 member 1 (Homo sapiens (Human)) | BDBM50152066 (5-Amino-4-oxo-6-phenyl-hexanoic acid benzyl ester ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9.15E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Tromsø Curated by ChEMBL | Assay Description Inhibition of [14C]-Gly-Sar transport by hPEPT1 in Caco-2 cell monolayers | J Med Chem 47: 4755-65 (2004) Article DOI: 10.1021/jm040780c BindingDB Entry DOI: 10.7270/Q2WM1CWG | |||||||||||
More data for this Ligand-Target Pair |