Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Kinesin-like protein KIF20A (Homo sapiens (Human)) | BDBM50140929 (CHEMBL3754608) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 230 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS Curated by ChEMBL | Assay Description Inhibition of microtubule-stimulated N-terminal MKLP-2 (56 to 505 residues) ATPase activity isolated from human hepatocellular carcinoma cells by pyr... | Bioorg Med Chem 24: 721-34 (2016) Article DOI: 10.1016/j.bmc.2015.12.042 BindingDB Entry DOI: 10.7270/Q29025NR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kinesin-like protein KIF20A (Homo sapiens (Human)) | BDBM50140923 (CHEMBL3753955) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 830 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS Curated by ChEMBL | Assay Description Inhibition of microtubule-stimulated N-terminal MKLP-2 (56 to 505 residues) ATPase activity isolated from human hepatocellular carcinoma cells by pyr... | Bioorg Med Chem 24: 721-34 (2016) Article DOI: 10.1016/j.bmc.2015.12.042 BindingDB Entry DOI: 10.7270/Q29025NR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kinesin-like protein KIF20A (Homo sapiens (Human)) | BDBM50140929 (CHEMBL3754608) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS Curated by ChEMBL | Assay Description Inhibition of N-terminal MKLP2 (56 to 505 residues) ATPase basal activity isolated from human hepatocellular carcinoma cells by pyruvate kinase/lacta... | Bioorg Med Chem 24: 721-34 (2016) Article DOI: 10.1016/j.bmc.2015.12.042 BindingDB Entry DOI: 10.7270/Q29025NR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kinesin-like protein KIF20A (Homo sapiens (Human)) | BDBM50140935 (CHEMBL3753380) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS Curated by ChEMBL | Assay Description Inhibition of microtubule-stimulated N-terminal MKLP-2 (56 to 505 residues) ATPase activity isolated from human hepatocellular carcinoma cells by pyr... | Bioorg Med Chem 24: 721-34 (2016) Article DOI: 10.1016/j.bmc.2015.12.042 BindingDB Entry DOI: 10.7270/Q29025NR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kinesin-like protein KIF20A (Homo sapiens (Human)) | BDBM50140923 (CHEMBL3753955) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.35E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS Curated by ChEMBL | Assay Description Inhibition of N-terminal MKLP2 (56 to 505 residues) ATPase basal activity isolated from human hepatocellular carcinoma cells by pyruvate kinase/lacta... | Bioorg Med Chem 24: 721-34 (2016) Article DOI: 10.1016/j.bmc.2015.12.042 BindingDB Entry DOI: 10.7270/Q29025NR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tubulin alpha-1A chain (Sus scrofa (Pig)) | BDBM50216333 (CHEBI:67357 | DOLASTATIN-10 | Dolastatin 10 | Dolo...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid PDB UniChem | PubMed | n/a | n/a | 2.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Laboratoire des M£canismes Mol£culaires des Communications Cellulaires (CNRS UPR 9023) Curated by ChEMBL | Assay Description Compound was tested in vitro for inhibition of tubulin polymerization. | Bioorg Med Chem Lett 8: 2855-8 (1999) BindingDB Entry DOI: 10.7270/Q2H41RX7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kinesin-like protein KIF20A (Homo sapiens (Human)) | BDBM50140931 (CHEMBL3753782) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS Curated by ChEMBL | Assay Description Inhibition of microtubule-stimulated N-terminal MKLP-2 (56 to 505 residues) ATPase activity isolated from human hepatocellular carcinoma cells by pyr... | Bioorg Med Chem 24: 721-34 (2016) Article DOI: 10.1016/j.bmc.2015.12.042 BindingDB Entry DOI: 10.7270/Q29025NR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kinesin-like protein KIF20A (Homo sapiens (Human)) | BDBM50140927 (CHEMBL3752100) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS Curated by ChEMBL | Assay Description Inhibition of N-terminal MKLP2 (56 to 505 residues) ATPase basal activity isolated from human hepatocellular carcinoma cells by pyruvate kinase/lacta... | Bioorg Med Chem 24: 721-34 (2016) Article DOI: 10.1016/j.bmc.2015.12.042 BindingDB Entry DOI: 10.7270/Q29025NR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kinesin-like protein KIF20A (Homo sapiens (Human)) | BDBM50140931 (CHEMBL3753782) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS Curated by ChEMBL | Assay Description Inhibition of N-terminal MKLP2 (56 to 505 residues) ATPase basal activity isolated from human hepatocellular carcinoma cells by pyruvate kinase/lacta... | Bioorg Med Chem 24: 721-34 (2016) Article DOI: 10.1016/j.bmc.2015.12.042 BindingDB Entry DOI: 10.7270/Q29025NR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kinesin-like protein KIF20A (Homo sapiens (Human)) | BDBM50140928 (CHEMBL3752687) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS Curated by ChEMBL | Assay Description Inhibition of microtubule-stimulated N-terminal MKLP-2 (56 to 505 residues) ATPase activity isolated from human hepatocellular carcinoma cells by pyr... | Bioorg Med Chem 24: 721-34 (2016) Article DOI: 10.1016/j.bmc.2015.12.042 BindingDB Entry DOI: 10.7270/Q29025NR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kinesin-like protein KIF20A (Homo sapiens (Human)) | BDBM50140930 (CHEMBL3753970) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS Curated by ChEMBL | Assay Description Inhibition of microtubule-stimulated N-terminal MKLP-2 (56 to 505 residues) ATPase activity isolated from human hepatocellular carcinoma cells by pyr... | Bioorg Med Chem 24: 721-34 (2016) Article DOI: 10.1016/j.bmc.2015.12.042 BindingDB Entry DOI: 10.7270/Q29025NR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kinesin-like protein KIF20A (Homo sapiens (Human)) | BDBM50140930 (CHEMBL3753970) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS Curated by ChEMBL | Assay Description Inhibition of N-terminal MKLP2 (56 to 505 residues) ATPase basal activity isolated from human hepatocellular carcinoma cells by pyruvate kinase/lacta... | Bioorg Med Chem 24: 721-34 (2016) Article DOI: 10.1016/j.bmc.2015.12.042 BindingDB Entry DOI: 10.7270/Q29025NR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kinesin-like protein KIF20A (Homo sapiens (Human)) | BDBM50140926 (CHEMBL3752869) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS Curated by ChEMBL | Assay Description Inhibition of microtubule-stimulated N-terminal MKLP-2 (56 to 505 residues) ATPase activity isolated from human hepatocellular carcinoma cells by pyr... | Bioorg Med Chem 24: 721-34 (2016) Article DOI: 10.1016/j.bmc.2015.12.042 BindingDB Entry DOI: 10.7270/Q29025NR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kinesin-like protein KIF20A (Homo sapiens (Human)) | BDBM50140927 (CHEMBL3752100) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS Curated by ChEMBL | Assay Description Inhibition of microtubule-stimulated N-terminal MKLP-2 (56 to 505 residues) ATPase activity isolated from human hepatocellular carcinoma cells by pyr... | Bioorg Med Chem 24: 721-34 (2016) Article DOI: 10.1016/j.bmc.2015.12.042 BindingDB Entry DOI: 10.7270/Q29025NR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kinesin-like protein KIF20A (Homo sapiens (Human)) | BDBM50140926 (CHEMBL3752869) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.01E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS Curated by ChEMBL | Assay Description Inhibition of N-terminal MKLP2 (56 to 505 residues) ATPase basal activity isolated from human hepatocellular carcinoma cells by pyruvate kinase/lacta... | Bioorg Med Chem 24: 721-34 (2016) Article DOI: 10.1016/j.bmc.2015.12.042 BindingDB Entry DOI: 10.7270/Q29025NR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kinesin-like protein KIF20A (Homo sapiens (Human)) | BDBM50140932 (CHEMBL3753668) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.02E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS Curated by ChEMBL | Assay Description Inhibition of microtubule-stimulated N-terminal MKLP-2 (56 to 505 residues) ATPase activity isolated from human hepatocellular carcinoma cells by pyr... | Bioorg Med Chem 24: 721-34 (2016) Article DOI: 10.1016/j.bmc.2015.12.042 BindingDB Entry DOI: 10.7270/Q29025NR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kinesin-like protein KIF20A (Homo sapiens (Human)) | BDBM50140932 (CHEMBL3753668) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS Curated by ChEMBL | Assay Description Inhibition of N-terminal MKLP2 (56 to 505 residues) ATPase basal activity isolated from human hepatocellular carcinoma cells by pyruvate kinase/lacta... | Bioorg Med Chem 24: 721-34 (2016) Article DOI: 10.1016/j.bmc.2015.12.042 BindingDB Entry DOI: 10.7270/Q29025NR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kinesin-like protein KIF20A (Homo sapiens (Human)) | BDBM50140928 (CHEMBL3752687) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.43E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS Curated by ChEMBL | Assay Description Inhibition of N-terminal MKLP2 (56 to 505 residues) ATPase basal activity isolated from human hepatocellular carcinoma cells by pyruvate kinase/lacta... | Bioorg Med Chem 24: 721-34 (2016) Article DOI: 10.1016/j.bmc.2015.12.042 BindingDB Entry DOI: 10.7270/Q29025NR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kinesin-like protein KIF20A (Homo sapiens (Human)) | BDBM50140936 (CHEMBL3752183) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.52E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS Curated by ChEMBL | Assay Description Inhibition of microtubule-stimulated N-terminal MKLP-2 (56 to 505 residues) ATPase activity isolated from human hepatocellular carcinoma cells by pyr... | Bioorg Med Chem 24: 721-34 (2016) Article DOI: 10.1016/j.bmc.2015.12.042 BindingDB Entry DOI: 10.7270/Q29025NR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kinesin-like protein KIF20A (Homo sapiens (Human)) | BDBM50140924 (CHEMBL3752271) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.85E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS Curated by ChEMBL | Assay Description Inhibition of N-terminal MKLP2 (56 to 505 residues) ATPase basal activity isolated from human hepatocellular carcinoma cells by pyruvate kinase/lacta... | Bioorg Med Chem 24: 721-34 (2016) Article DOI: 10.1016/j.bmc.2015.12.042 BindingDB Entry DOI: 10.7270/Q29025NR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kinesin-like protein KIF20A (Homo sapiens (Human)) | BDBM50140925 (CHEMBL3754386) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS Curated by ChEMBL | Assay Description Inhibition of microtubule-stimulated N-terminal MKLP-2 (56 to 505 residues) ATPase activity isolated from human hepatocellular carcinoma cells by pyr... | Bioorg Med Chem 24: 721-34 (2016) Article DOI: 10.1016/j.bmc.2015.12.042 BindingDB Entry DOI: 10.7270/Q29025NR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kinesin-like protein KIF20A (Homo sapiens (Human)) | BDBM50140934 (CHEMBL3754004) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.98E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS Curated by ChEMBL | Assay Description Inhibition of microtubule-stimulated N-terminal MKLP-2 (56 to 505 residues) ATPase activity isolated from human hepatocellular carcinoma cells by pyr... | Bioorg Med Chem 24: 721-34 (2016) Article DOI: 10.1016/j.bmc.2015.12.042 BindingDB Entry DOI: 10.7270/Q29025NR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kinesin-like protein KIF20A (Homo sapiens (Human)) | BDBM50140933 (CHEMBL3753648) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.31E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS Curated by ChEMBL | Assay Description Inhibition of N-terminal MKLP2 (56 to 505 residues) ATPase basal activity isolated from human hepatocellular carcinoma cells by pyruvate kinase/lacta... | Bioorg Med Chem 24: 721-34 (2016) Article DOI: 10.1016/j.bmc.2015.12.042 BindingDB Entry DOI: 10.7270/Q29025NR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kinesin-like protein KIF20A (Homo sapiens (Human)) | BDBM50140925 (CHEMBL3754386) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS Curated by ChEMBL | Assay Description Inhibition of N-terminal MKLP2 (56 to 505 residues) ATPase basal activity isolated from human hepatocellular carcinoma cells by pyruvate kinase/lacta... | Bioorg Med Chem 24: 721-34 (2016) Article DOI: 10.1016/j.bmc.2015.12.042 BindingDB Entry DOI: 10.7270/Q29025NR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kinesin-like protein KIF20A (Homo sapiens (Human)) | BDBM50140933 (CHEMBL3753648) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.45E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS Curated by ChEMBL | Assay Description Inhibition of microtubule-stimulated N-terminal MKLP-2 (56 to 505 residues) ATPase activity isolated from human hepatocellular carcinoma cells by pyr... | Bioorg Med Chem 24: 721-34 (2016) Article DOI: 10.1016/j.bmc.2015.12.042 BindingDB Entry DOI: 10.7270/Q29025NR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tubulin alpha-1A chain (Sus scrofa (Pig)) | BDBM50072182 ((2S,5S,6R,7S,14R,15S,18S,21S,22R)-2-Benzyl-15-((S)...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 3.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Laboratoire des M£canismes Mol£culaires des Communications Cellulaires (CNRS UPR 9023) Curated by ChEMBL | Assay Description Compound was tested in vitro for inhibition of tubulin polymerization | Bioorg Med Chem Lett 8: 2855-8 (1999) BindingDB Entry DOI: 10.7270/Q2H41RX7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kinesin-like protein KIF20A (Homo sapiens (Human)) | BDBM50140934 (CHEMBL3754004) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS Curated by ChEMBL | Assay Description Inhibition of N-terminal MKLP2 (56 to 505 residues) ATPase basal activity isolated from human hepatocellular carcinoma cells by pyruvate kinase/lacta... | Bioorg Med Chem 24: 721-34 (2016) Article DOI: 10.1016/j.bmc.2015.12.042 BindingDB Entry DOI: 10.7270/Q29025NR | |||||||||||
More data for this Ligand-Target Pair |