Compile Data Set for Download or QSAR

Found 60 hits with Last Name = 'valkov' and Initial = 'v'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone acetyltransferase KAT2B (Homo sapiens (Human))	BDBM50346554 (CHEMBL106011) Show SMILES Fc1ccc(cc1)-n1sc2ncccc2c1=O Show InChI InChI=1S/C12H7FN2OS/c13-8-3-5-9(6-4-8)15-12(16)10-2-1-7-14-11(10)17-15/h1-7H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	720	n/a	n/a	n/a	n/a	n/a	n/a
Albert-Ludwigs-University of Freiburg Curated by ChEMBL					Assay Description Inhibition of histone acetylase activity of human recombinant PCAF expressed in Escherichia coli using biotinylated oligopeptide sequences from histo...				Bioorg Med Chem 19: 3678-89 (2011) Article DOI: 10.1016/j.bmc.2011.01.063 BindingDB Entry DOI: 10.7270/Q2NV9JKS
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT2B (Homo sapiens (Human))	BDBM50346563 (CHEMBL1795605) Show SMILES [O-][N+](=O)c1cnc2sn(-c3ccc(Br)cc3)c(=O)c2c1 Show InChI InChI=1S/C12H6BrN3O3S/c13-7-1-3-8(4-2-7)15-12(17)10-5-9(16(18)19)6-14-11(10)20-15/h1-6H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	860	n/a	n/a	n/a	n/a	n/a	n/a
Albert-Ludwigs-University of Freiburg Curated by ChEMBL					Assay Description Inhibition of histone acetylase activity of human recombinant PCAF expressed in Escherichia coli using biotinylated oligopeptide sequences from histo...				Bioorg Med Chem 19: 3678-89 (2011) Article DOI: 10.1016/j.bmc.2011.01.063 BindingDB Entry DOI: 10.7270/Q2NV9JKS
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50346550 (CHEMBL270110) Show SMILES Cc1ccc(cc1)[C@H]1CC(=O)Oc2ccc3cc(C)ccc3c12 Show InChI InChI=1S/C21H18O2/c1-13-3-6-15(7-4-13)18-12-20(22)23-19-10-8-16-11-14(2)5-9-17(16)21(18)19/h3-11,18H,12H2,1-2H3/t18-/m1/s1	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Albert-Ludwigs-Universit£t Freiburg Curated by ChEMBL					Assay Description Inhibition of human recombinant Sirt2 expressed in Escherichia coli BL21 by fluorescent deacetylase assay				J Med Chem 51: 1203-13 (2008) Article DOI: 10.1021/jm700972e BindingDB Entry DOI: 10.7270/Q22N534Q
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50373762 (CHEMBL438203) Show SMILES Cc1ccc(cc1)C1CC(=O)Oc2ccc3cc(Br)ccc3c12 |w:7.7| Show InChI InChI=1S/C20H15BrO2/c1-12-2-4-13(5-3-12)17-11-19(22)23-18-9-6-14-10-15(21)7-8-16(14)20(17)18/h2-10,17H,11H2,1H3	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Albert-Ludwigs-Universit£t Freiburg Curated by ChEMBL					Assay Description Inhibition of human recombinant Sirt2 expressed in Escherichia coli BL21 by fluorescent deacetylase assay				J Med Chem 51: 1203-13 (2008) Article DOI: 10.1021/jm700972e BindingDB Entry DOI: 10.7270/Q22N534Q
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50346550 (CHEMBL270110) Show SMILES Cc1ccc(cc1)[C@H]1CC(=O)Oc2ccc3cc(C)ccc3c12 Show InChI InChI=1S/C21H18O2/c1-13-3-6-15(7-4-13)18-12-20(22)23-19-10-8-16-11-14(2)5-9-17(16)21(18)19/h3-11,18H,12H2,1-2H3/t18-/m1/s1	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Albert-Ludwigs-Universit£t Freiburg Curated by ChEMBL					Assay Description Inhibition of human recombinant Sirt2 expressed in Escherichia coli BL21 by fluorescent deacetylase assay				J Med Chem 51: 1203-13 (2008) Article DOI: 10.1021/jm700972e BindingDB Entry DOI: 10.7270/Q22N534Q
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT2B (Homo sapiens (Human))	BDBM50346554 (CHEMBL106011) Show SMILES Fc1ccc(cc1)-n1sc2ncccc2c1=O Show InChI InChI=1S/C12H7FN2OS/c13-8-3-5-9(6-4-8)15-12(16)10-2-1-7-14-11(10)17-15/h1-7H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.64E+3	n/a	n/a	n/a	n/a	n/a	n/a
Albert-Ludwigs-University of Freiburg Curated by ChEMBL					Assay Description Inhibition of histone acetylase activity of human recombinant PCAF expressed in Escherichia coli using biotinylated oligopeptide sequences from histo...				Bioorg Med Chem 19: 3678-89 (2011) Article DOI: 10.1016/j.bmc.2011.01.063 BindingDB Entry DOI: 10.7270/Q2NV9JKS
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT2B (Homo sapiens (Human))	BDBM50346555 (CHEMBL1795609) Show SMILES COc1ccc(cc1)-n1sc2ncc(cc2c1=O)[N+]([O-])=O Show InChI InChI=1S/C13H9N3O4S/c1-20-10-4-2-8(3-5-10)15-13(17)11-6-9(16(18)19)7-14-12(11)21-15/h2-7H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.83E+3	n/a	n/a	n/a	n/a	n/a	n/a
Albert-Ludwigs-University of Freiburg Curated by ChEMBL					Assay Description Inhibition of histone acetylase activity of human recombinant PCAF expressed in Escherichia coli using biotinylated oligopeptide sequences from histo...				Bioorg Med Chem 19: 3678-89 (2011) Article DOI: 10.1016/j.bmc.2011.01.063 BindingDB Entry DOI: 10.7270/Q2NV9JKS
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50373754 (CHEMBL273076) Show SMILES Cc1ccc(cc1F)C1CC(=O)Oc2ccc3cc(Br)ccc3c12 |w:8.8| Show InChI InChI=1S/C20H14BrFO2/c1-11-2-3-13(9-17(11)22)16-10-19(23)24-18-7-4-12-8-14(21)5-6-15(12)20(16)18/h2-9,16H,10H2,1H3	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Albert-Ludwigs-Universit£t Freiburg Curated by ChEMBL					Assay Description Inhibition of human recombinant Sirt2 expressed in Escherichia coli BL21 by fluorescent deacetylase assay				J Med Chem 51: 1203-13 (2008) Article DOI: 10.1021/jm700972e BindingDB Entry DOI: 10.7270/Q22N534Q
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50373755 (CHEMBL270478) Show SMILES Cc1ccc(cc1Cl)C1CC(=O)Oc2ccc3cc(Br)ccc3c12 |w:8.8| Show InChI InChI=1S/C20H14BrClO2/c1-11-2-3-13(9-17(11)22)16-10-19(23)24-18-7-4-12-8-14(21)5-6-15(12)20(16)18/h2-9,16H,10H2,1H3	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Albert-Ludwigs-Universit£t Freiburg Curated by ChEMBL					Assay Description Inhibition of human recombinant Sirt2 expressed in Escherichia coli BL21 by fluorescent deacetylase assay				J Med Chem 51: 1203-13 (2008) Article DOI: 10.1021/jm700972e BindingDB Entry DOI: 10.7270/Q22N534Q
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50373756 (CHEMBL407517) Show SMILES COc1cccc(c1)C1CC(=O)Oc2ccc3cc(Br)ccc3c12 |w:8.8| Show InChI InChI=1S/C20H15BrO3/c1-23-15-4-2-3-12(10-15)17-11-19(22)24-18-8-5-13-9-14(21)6-7-16(13)20(17)18/h2-10,17H,11H2,1H3	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Albert-Ludwigs-Universit£t Freiburg Curated by ChEMBL					Assay Description Inhibition of human recombinant Sirt2 expressed in Escherichia coli BL21 by fluorescent deacetylase assay				J Med Chem 51: 1203-13 (2008) Article DOI: 10.1021/jm700972e BindingDB Entry DOI: 10.7270/Q22N534Q
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT2B (Homo sapiens (Human))	BDBM50346556 (CHEMBL1795611) Show SMILES Cc1cnc2sn(-c3ccc(cc3)[N+]([O-])=O)c(=O)c2c1 Show InChI InChI=1S/C13H9N3O3S/c1-8-6-11-12(14-7-8)20-15(13(11)17)9-2-4-10(5-3-9)16(18)19/h2-7H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.72E+3	n/a	n/a	n/a	n/a	n/a	n/a
Albert-Ludwigs-University of Freiburg Curated by ChEMBL					Assay Description Inhibition of histone acetylase activity of human recombinant PCAF expressed in Escherichia coli using biotinylated oligopeptide sequences from histo...				Bioorg Med Chem 19: 3678-89 (2011) Article DOI: 10.1016/j.bmc.2011.01.063 BindingDB Entry DOI: 10.7270/Q2NV9JKS
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT2B (Homo sapiens (Human))	BDBM50346557 (CHEMBL99137) Show SMILES [O-][N+](=O)c1ccc(cc1)-n1sc2ncccc2c1=O Show InChI InChI=1S/C12H7N3O3S/c16-12-10-2-1-7-13-11(10)19-14(12)8-3-5-9(6-4-8)15(17)18/h1-7H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.99E+3	n/a	n/a	n/a	n/a	n/a	n/a
Albert-Ludwigs-University of Freiburg Curated by ChEMBL					Assay Description Inhibition of histone acetylase activity of human recombinant PCAF expressed in Escherichia coli using biotinylated oligopeptide sequences from histo...				Bioorg Med Chem 19: 3678-89 (2011) Article DOI: 10.1016/j.bmc.2011.01.063 BindingDB Entry DOI: 10.7270/Q2NV9JKS
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT2B (Homo sapiens (Human))	BDBM50346561 (CHEMBL1795604) Show SMILES Cc1cnc2sn(-c3ccc(Br)cc3)c(=O)c2c1 Show InChI InChI=1S/C13H9BrN2OS/c1-8-6-11-12(15-7-8)18-16(13(11)17)10-4-2-9(14)3-5-10/h2-7H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.99E+3	n/a	n/a	n/a	n/a	n/a	n/a
Albert-Ludwigs-University of Freiburg Curated by ChEMBL					Assay Description Inhibition of histone acetylase activity of human recombinant PCAF expressed in Escherichia coli using biotinylated oligopeptide sequences from histo...				Bioorg Med Chem 19: 3678-89 (2011) Article DOI: 10.1016/j.bmc.2011.01.063 BindingDB Entry DOI: 10.7270/Q2NV9JKS
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50373751 (CHEMBL407059) Show SMILES Cc1ccc2c3C(CC(=O)Oc3ccc2c1)c1cccc(c1)C#N |w:6.18| Show InChI InChI=1S/C21H15NO2/c1-13-5-7-17-16(9-13)6-8-19-21(17)18(11-20(23)24-19)15-4-2-3-14(10-15)12-22/h2-10,18H,11H2,1H3	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Albert-Ludwigs-Universit£t Freiburg Curated by ChEMBL					Assay Description Inhibition of human recombinant Sirt2 expressed in Escherichia coli BL21 by fluorescent deacetylase assay				J Med Chem 51: 1203-13 (2008) Article DOI: 10.1021/jm700972e BindingDB Entry DOI: 10.7270/Q22N534Q
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50373757 (CHEMBL409006) Show SMILES Fc1cccc(c1)C1CC(=O)Oc2ccc3cc(Br)ccc3c12 |w:7.7| Show InChI InChI=1S/C19H12BrFO2/c20-13-5-6-15-12(8-13)4-7-17-19(15)16(10-18(22)23-17)11-2-1-3-14(21)9-11/h1-9,16H,10H2	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Albert-Ludwigs-Universit£t Freiburg Curated by ChEMBL					Assay Description Inhibition of human recombinant Sirt2 expressed in Escherichia coli BL21 by fluorescent deacetylase assay				J Med Chem 51: 1203-13 (2008) Article DOI: 10.1021/jm700972e BindingDB Entry DOI: 10.7270/Q22N534Q
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50373753 (CHEMBL261605) Show SMILES Cc1ccc2c3[C@H](CC(=O)Oc3ccc2c1)c1ccccc1 Show InChI InChI=1S/C20H16O2/c1-13-7-9-16-15(11-13)8-10-18-20(16)17(12-19(21)22-18)14-5-3-2-4-6-14/h2-11,17H,12H2,1H3/t17-/m1/s1	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Albert-Ludwigs-Universit£t Freiburg Curated by ChEMBL					Assay Description Inhibition of human recombinant Sirt2 expressed in Escherichia coli BL21 by fluorescent deacetylase assay				J Med Chem 51: 1203-13 (2008) Article DOI: 10.1021/jm700972e BindingDB Entry DOI: 10.7270/Q22N534Q
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50373752 (CHEMBL270109) Show SMILES Cc1ccc2c3C(CC(=O)Oc3ccc2c1)c1ccc(C)c(F)c1 |w:6.18| Show InChI InChI=1S/C21H17FO2/c1-12-3-7-16-14(9-12)6-8-19-21(16)17(11-20(23)24-19)15-5-4-13(2)18(22)10-15/h3-10,17H,11H2,1-2H3	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Albert-Ludwigs-Universit£t Freiburg Curated by ChEMBL					Assay Description Inhibition of human recombinant Sirt2 expressed in Escherichia coli BL21 by fluorescent deacetylase assay				J Med Chem 51: 1203-13 (2008) Article DOI: 10.1021/jm700972e BindingDB Entry DOI: 10.7270/Q22N534Q
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT2B (Homo sapiens (Human))	BDBM50346555 (CHEMBL1795609) Show SMILES COc1ccc(cc1)-n1sc2ncc(cc2c1=O)[N+]([O-])=O Show InChI InChI=1S/C13H9N3O4S/c1-20-10-4-2-8(3-5-10)15-13(17)11-6-9(16(18)19)7-14-12(11)21-15/h2-7H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.42E+3	n/a	n/a	n/a	n/a	n/a	n/a
Albert-Ludwigs-University of Freiburg Curated by ChEMBL					Assay Description Inhibition of histone acetylase activity of human recombinant PCAF expressed in Escherichia coli using biotinylated oligopeptide sequences from histo...				Bioorg Med Chem 19: 3678-89 (2011) Article DOI: 10.1016/j.bmc.2011.01.063 BindingDB Entry DOI: 10.7270/Q2NV9JKS
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT2B (Homo sapiens (Human))	BDBM50346567 (CHEMBL318367) Show SMILES Clc1ccc(cc1)-n1sc2ncccc2c1=O Show InChI InChI=1S/C12H7ClN2OS/c13-8-3-5-9(6-4-8)15-12(16)10-2-1-7-14-11(10)17-15/h1-7H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.53E+3	n/a	n/a	n/a	n/a	n/a	n/a
Albert-Ludwigs-University of Freiburg Curated by ChEMBL					Assay Description Inhibition of histone acetylase activity of human recombinant PCAF expressed in Escherichia coli using biotinylated oligopeptide sequences from histo...				Bioorg Med Chem 19: 3678-89 (2011) Article DOI: 10.1016/j.bmc.2011.01.063 BindingDB Entry DOI: 10.7270/Q2NV9JKS
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT2B (Homo sapiens (Human))	BDBM50346579 (CHEMBL1795800) Show SMILES Cc1ccc(cc1)-n1sc2cc(F)ccc2c1=O Show InChI InChI=1S/C14H10FNOS/c1-9-2-5-11(6-3-9)16-14(17)12-7-4-10(15)8-13(12)18-16/h2-8H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.69E+3	n/a	n/a	n/a	n/a	n/a	n/a
Albert-Ludwigs-University of Freiburg Curated by ChEMBL					Assay Description Inhibition of histone acetylase activity of human recombinant PCAF expressed in Escherichia coli using biotinylated oligopeptide sequences from histo...				Bioorg Med Chem 19: 3678-89 (2011) Article DOI: 10.1016/j.bmc.2011.01.063 BindingDB Entry DOI: 10.7270/Q2NV9JKS
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT2B (Homo sapiens (Human))	BDBM50346557 (CHEMBL99137) Show SMILES [O-][N+](=O)c1ccc(cc1)-n1sc2ncccc2c1=O Show InChI InChI=1S/C12H7N3O3S/c16-12-10-2-1-7-13-11(10)19-14(12)8-3-5-9(6-4-8)15(17)18/h1-7H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Albert-Ludwigs-University of Freiburg Curated by ChEMBL					Assay Description Inhibition of histone acetylase activity of human recombinant PCAF expressed in Escherichia coli using biotinylated oligopeptide sequences from histo...				Bioorg Med Chem 19: 3678-89 (2011) Article DOI: 10.1016/j.bmc.2011.01.063 BindingDB Entry DOI: 10.7270/Q2NV9JKS
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50373749 (CHEMBL271536) Show SMILES Cc1cccc(c1)C1CC(=O)Oc2ccc3cc(C)ccc3c12 |w:7.7| Show InChI InChI=1S/C21H18O2/c1-13-4-3-5-15(10-13)18-12-20(22)23-19-9-7-16-11-14(2)6-8-17(16)21(18)19/h3-11,18H,12H2,1-2H3	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Albert-Ludwigs-Universit£t Freiburg Curated by ChEMBL					Assay Description Inhibition of human recombinant Sirt2 expressed in Escherichia coli BL21 by fluorescent deacetylase assay				J Med Chem 51: 1203-13 (2008) Article DOI: 10.1021/jm700972e BindingDB Entry DOI: 10.7270/Q22N534Q
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT2B (Homo sapiens (Human))	BDBM50346562 (CHEMBL101422) Show SMILES Brc1ccc(cc1)-n1sc2ncccc2c1=O Show InChI InChI=1S/C12H7BrN2OS/c13-8-3-5-9(6-4-8)15-12(16)10-2-1-7-14-11(10)17-15/h1-7H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.43E+3	n/a	n/a	n/a	n/a	n/a	n/a
Albert-Ludwigs-University of Freiburg Curated by ChEMBL					Assay Description Inhibition of histone acetylase activity of human recombinant PCAF expressed in Escherichia coli using biotinylated oligopeptide sequences from histo...				Bioorg Med Chem 19: 3678-89 (2011) Article DOI: 10.1016/j.bmc.2011.01.063 BindingDB Entry DOI: 10.7270/Q2NV9JKS
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT2B (Homo sapiens (Human))	BDBM50346568 (CHEMBL1795614) Show SMILES Clc1ccc(cc1Cl)-n1sc2ncccc2c1=O Show InChI InChI=1S/C12H6Cl2N2OS/c13-9-4-3-7(6-10(9)14)16-12(17)8-2-1-5-15-11(8)18-16/h1-6H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.57E+3	n/a	n/a	n/a	n/a	n/a	n/a
Albert-Ludwigs-University of Freiburg Curated by ChEMBL					Assay Description Inhibition of histone acetylase activity of human recombinant PCAF expressed in Escherichia coli using biotinylated oligopeptide sequences from histo...				Bioorg Med Chem 19: 3678-89 (2011) Article DOI: 10.1016/j.bmc.2011.01.063 BindingDB Entry DOI: 10.7270/Q2NV9JKS
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT2B (Homo sapiens (Human))	BDBM50346570 (CHEMBL1795616) Show SMILES Cc1ccc(cc1)-n1sc2ncccc2c1=O Show InChI InChI=1S/C13H10N2OS/c1-9-4-6-10(7-5-9)15-13(16)11-3-2-8-14-12(11)17-15/h2-8H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.63E+3	n/a	n/a	n/a	n/a	n/a	n/a
Albert-Ludwigs-University of Freiburg Curated by ChEMBL					Assay Description Inhibition of histone acetylase activity of human recombinant PCAF expressed in Escherichia coli using biotinylated oligopeptide sequences from histo...				Bioorg Med Chem 19: 3678-89 (2011) Article DOI: 10.1016/j.bmc.2011.01.063 BindingDB Entry DOI: 10.7270/Q2NV9JKS
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT2B (Homo sapiens (Human))	BDBM50346580 (CHEMBL1795796) Show SMILES [O-][N+](=O)c1cc(ccc1Cl)-n1sccc1=O Show InChI InChI=1S/C9H5ClN2O3S/c10-7-2-1-6(5-8(7)12(14)15)11-9(13)3-4-16-11/h1-5H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Albert-Ludwigs-University of Freiburg Curated by ChEMBL					Assay Description Inhibition of histone acetylase activity of human recombinant PCAF expressed in Escherichia coli using biotinylated oligopeptide sequences from histo...				Bioorg Med Chem 19: 3678-89 (2011) Article DOI: 10.1016/j.bmc.2011.01.063 BindingDB Entry DOI: 10.7270/Q2NV9JKS
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT2B (Homo sapiens (Human))	BDBM50346563 (CHEMBL1795605) Show SMILES [O-][N+](=O)c1cnc2sn(-c3ccc(Br)cc3)c(=O)c2c1 Show InChI InChI=1S/C12H6BrN3O3S/c13-7-1-3-8(4-2-7)15-12(17)10-5-9(16(18)19)6-14-11(10)20-15/h1-6H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.91E+3	n/a	n/a	n/a	n/a	n/a	n/a
Albert-Ludwigs-University of Freiburg Curated by ChEMBL					Assay Description Inhibition of histone acetylase activity of human recombinant PCAF expressed in Escherichia coli using biotinylated oligopeptide sequences from histo...				Bioorg Med Chem 19: 3678-89 (2011) Article DOI: 10.1016/j.bmc.2011.01.063 BindingDB Entry DOI: 10.7270/Q2NV9JKS
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT2B (Homo sapiens (Human))	BDBM50346571 (CHEMBL102387) Show SMILES COc1cccc(c1)-n1sc2ncccc2c1=O Show InChI InChI=1S/C13H10N2O2S/c1-17-10-5-2-4-9(8-10)15-13(16)11-6-3-7-14-12(11)18-15/h2-8H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.03E+3	n/a	n/a	n/a	n/a	n/a	n/a
Albert-Ludwigs-University of Freiburg Curated by ChEMBL					Assay Description Inhibition of histone acetylase activity of human recombinant PCAF expressed in Escherichia coli using biotinylated oligopeptide sequences from histo...				Bioorg Med Chem 19: 3678-89 (2011) Article DOI: 10.1016/j.bmc.2011.01.063 BindingDB Entry DOI: 10.7270/Q2NV9JKS
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50373763 (CHEMBL270292) Show SMILES Brc1ccc2c3C(CC(=O)Oc3ccc2c1)c1ccccc1 |w:6.18| Show InChI InChI=1S/C19H13BrO2/c20-14-7-8-15-13(10-14)6-9-17-19(15)16(11-18(21)22-17)12-4-2-1-3-5-12/h1-10,16H,11H2	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Albert-Ludwigs-Universit£t Freiburg Curated by ChEMBL					Assay Description Inhibition of human recombinant Sirt2 expressed in Escherichia coli BL21 by fluorescent deacetylase assay				J Med Chem 51: 1203-13 (2008) Article DOI: 10.1021/jm700972e BindingDB Entry DOI: 10.7270/Q22N534Q
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50373761 (CHEMBL270291) Show SMILES COc1ccc(cc1)C1CC(=O)Oc2ccc3cc(Br)ccc3c12 |w:8.8| Show InChI InChI=1S/C20H15BrO3/c1-23-15-6-2-12(3-7-15)17-11-19(22)24-18-9-4-13-10-14(21)5-8-16(13)20(17)18/h2-10,17H,11H2,1H3	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Albert-Ludwigs-Universit£t Freiburg Curated by ChEMBL					Assay Description Inhibition of human recombinant Sirt2 expressed in Escherichia coli BL21 by fluorescent deacetylase assay				J Med Chem 51: 1203-13 (2008) Article DOI: 10.1021/jm700972e BindingDB Entry DOI: 10.7270/Q22N534Q
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT2B (Homo sapiens (Human))	BDBM50346565 (CHEMBL95284) Show SMILES COc1ccc(cc1)-n1sc2ncccc2c1=O Show InChI InChI=1S/C13H10N2O2S/c1-17-10-6-4-9(5-7-10)15-13(16)11-3-2-8-14-12(11)18-15/h2-8H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.71E+3	n/a	n/a	n/a	n/a	n/a	n/a
Albert-Ludwigs-University of Freiburg Curated by ChEMBL					Assay Description Inhibition of histone acetylase activity of human recombinant PCAF expressed in Escherichia coli using biotinylated oligopeptide sequences from histo...				Bioorg Med Chem 19: 3678-89 (2011) Article DOI: 10.1016/j.bmc.2011.01.063 BindingDB Entry DOI: 10.7270/Q2NV9JKS
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT2B (Homo sapiens (Human))	BDBM50346569 (CHEMBL1795615) Show SMILES Fc1ccc(cc1F)-n1sc2ncccc2c1=O Show InChI InChI=1S/C12H6F2N2OS/c13-9-4-3-7(6-10(9)14)16-12(17)8-2-1-5-15-11(8)18-16/h1-6H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Albert-Ludwigs-University of Freiburg Curated by ChEMBL					Assay Description Inhibition of histone acetylase activity of human recombinant PCAF expressed in Escherichia coli using biotinylated oligopeptide sequences from histo...				Bioorg Med Chem 19: 3678-89 (2011) Article DOI: 10.1016/j.bmc.2011.01.063 BindingDB Entry DOI: 10.7270/Q2NV9JKS
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50373746 (CHEMBL402446) Show SMILES Brc1ccc2c3C(CC(=O)Nc3ccc2c1)c1ccccc1 |w:6.18| Show InChI InChI=1S/C19H14BrNO/c20-14-7-8-15-13(10-14)6-9-17-19(15)16(11-18(22)21-17)12-4-2-1-3-5-12/h1-10,16H,11H2,(H,21,22)	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Albert-Ludwigs-Universit£t Freiburg Curated by ChEMBL					Assay Description Inhibition of human recombinant Sirt2 expressed in Escherichia coli BL21 by fluorescent deacetylase assay				J Med Chem 51: 1203-13 (2008) Article DOI: 10.1021/jm700972e BindingDB Entry DOI: 10.7270/Q22N534Q
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT2B (Homo sapiens (Human))	BDBM50346581 (CHEMBL1795612) Show SMILES COc1ccc(cc1)-n1sc2ncc(C)cc2c1=O Show InChI InChI=1S/C14H12N2O2S/c1-9-7-12-13(15-8-9)19-16(14(12)17)10-3-5-11(18-2)6-4-10/h3-8H,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.51E+3	n/a	n/a	n/a	n/a	n/a	n/a
Albert-Ludwigs-University of Freiburg Curated by ChEMBL					Assay Description Inhibition of histone acetylase activity of human recombinant PCAF expressed in Escherichia coli using biotinylated oligopeptide sequences from histo...				Bioorg Med Chem 19: 3678-89 (2011) Article DOI: 10.1016/j.bmc.2011.01.063 BindingDB Entry DOI: 10.7270/Q2NV9JKS
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT2B (Homo sapiens (Human))	BDBM50346574 (CHEMBL1795619) Show SMILES Clc1ccc(Cn2sc3ncccc3c2=O)cc1Cl Show InChI InChI=1S/C13H8Cl2N2OS/c14-10-4-3-8(6-11(10)15)7-17-13(18)9-2-1-5-16-12(9)19-17/h1-6H,7H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.94E+3	n/a	n/a	n/a	n/a	n/a	n/a
Albert-Ludwigs-University of Freiburg Curated by ChEMBL					Assay Description Inhibition of histone acetylase activity of human recombinant PCAF expressed in Escherichia coli using biotinylated oligopeptide sequences from histo...				Bioorg Med Chem 19: 3678-89 (2011) Article DOI: 10.1016/j.bmc.2011.01.063 BindingDB Entry DOI: 10.7270/Q2NV9JKS
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT2B (Homo sapiens (Human))	BDBM50346560 (CHEMBL1795799) Show SMILES [O-][N+](=O)c1ccc2c(c1)sn(Cc1ccccc1)c2=O Show InChI InChI=1S/C14H10N2O3S/c17-14-12-7-6-11(16(18)19)8-13(12)20-15(14)9-10-4-2-1-3-5-10/h1-8H,9H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.66E+3	n/a	n/a	n/a	n/a	n/a	n/a
Albert-Ludwigs-University of Freiburg Curated by ChEMBL					Assay Description Inhibition of histone acetylase activity of human recombinant PCAF expressed in Escherichia coli using biotinylated oligopeptide sequences from histo...				Bioorg Med Chem 19: 3678-89 (2011) Article DOI: 10.1016/j.bmc.2011.01.063 BindingDB Entry DOI: 10.7270/Q2NV9JKS
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT2B (Homo sapiens (Human))	BDBM50037078 (2-(Phenyl)-isothiazolo[5,4-b]pyridin-3(2H)-one | 2...) Show SMILES O=c1n(sc2ncccc12)-c1ccccc1 Show InChI InChI=1S/C12H8N2OS/c15-12-10-7-4-8-13-11(10)16-14(12)9-5-2-1-3-6-9/h1-8H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.85E+3	n/a	n/a	n/a	n/a	n/a	n/a
Albert-Ludwigs-University of Freiburg Curated by ChEMBL					Assay Description Inhibition of histone acetylase activity of human recombinant PCAF expressed in Escherichia coli using biotinylated oligopeptide sequences from histo...				Bioorg Med Chem 19: 3678-89 (2011) Article DOI: 10.1016/j.bmc.2011.01.063 BindingDB Entry DOI: 10.7270/Q2NV9JKS
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50373760 (CHEMBL405156) Show SMILES Fc1ccc(cc1)C1CC(=O)Oc2ccc3cc(Br)ccc3c12 |w:7.7| Show InChI InChI=1S/C19H12BrFO2/c20-13-4-7-15-12(9-13)3-8-17-19(15)16(10-18(22)23-17)11-1-5-14(21)6-2-11/h1-9,16H,10H2	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Albert-Ludwigs-Universit£t Freiburg Curated by ChEMBL					Assay Description Inhibition of human recombinant Sirt2 expressed in Escherichia coli BL21 by fluorescent deacetylase assay				J Med Chem 51: 1203-13 (2008) Article DOI: 10.1021/jm700972e BindingDB Entry DOI: 10.7270/Q22N534Q
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50373748 (CHEMBL429433) Show SMILES Cc1ccc2c3C(CC(=O)Oc3ccc2c1)c1cccc(Br)c1 |w:6.18| Show InChI InChI=1S/C20H15BrO2/c1-12-5-7-16-14(9-12)6-8-18-20(16)17(11-19(22)23-18)13-3-2-4-15(21)10-13/h2-10,17H,11H2,1H3	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Albert-Ludwigs-Universit£t Freiburg Curated by ChEMBL					Assay Description Inhibition of human recombinant Sirt2 expressed in Escherichia coli BL21 by fluorescent deacetylase assay				J Med Chem 51: 1203-13 (2008) Article DOI: 10.1021/jm700972e BindingDB Entry DOI: 10.7270/Q22N534Q
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50373758 (CHEMBL270075) Show SMILES Brc1cccc(c1)C1CC(=O)Oc2ccc3cc(Br)ccc3c12 |w:7.7| Show InChI InChI=1S/C19H12Br2O2/c20-13-3-1-2-11(8-13)16-10-18(22)23-17-7-4-12-9-14(21)5-6-15(12)19(16)17/h1-9,16H,10H2	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.01E+4	n/a	n/a	n/a	n/a	n/a	n/a
Albert-Ludwigs-Universit£t Freiburg Curated by ChEMBL					Assay Description Inhibition of human recombinant Sirt2 expressed in Escherichia coli BL21 by fluorescent deacetylase assay				J Med Chem 51: 1203-13 (2008) Article DOI: 10.1021/jm700972e BindingDB Entry DOI: 10.7270/Q22N534Q
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50373753 (CHEMBL261605) Show SMILES Cc1ccc2c3[C@H](CC(=O)Oc3ccc2c1)c1ccccc1 Show InChI InChI=1S/C20H16O2/c1-13-7-9-16-15(11-13)8-10-18-20(16)17(12-19(21)22-18)14-5-3-2-4-6-14/h2-11,17H,12H2,1H3/t17-/m1/s1	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.06E+4	n/a	n/a	n/a	n/a	n/a	n/a
Albert-Ludwigs-Universit£t Freiburg Curated by ChEMBL					Assay Description Inhibition of human recombinant Sirt2 expressed in Escherichia coli BL21 by fluorescent deacetylase assay				J Med Chem 51: 1203-13 (2008) Article DOI: 10.1021/jm700972e BindingDB Entry DOI: 10.7270/Q22N534Q
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT2B (Homo sapiens (Human))	BDBM50346558 (CHEMBL1795606) Show SMILES [O-][N+](=O)c1ccc(cc1)-n1sc2ncc(cc2c1=O)[N+]([O-])=O Show InChI InChI=1S/C12H6N4O5S/c17-12-10-5-9(16(20)21)6-13-11(10)22-14(12)7-1-3-8(4-2-7)15(18)19/h1-6H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.18E+4	n/a	n/a	n/a	n/a	n/a	n/a
Albert-Ludwigs-University of Freiburg Curated by ChEMBL					Assay Description Inhibition of histone acetylase activity of human recombinant PCAF expressed in Escherichia coli using biotinylated oligopeptide sequences from histo...				Bioorg Med Chem 19: 3678-89 (2011) Article DOI: 10.1016/j.bmc.2011.01.063 BindingDB Entry DOI: 10.7270/Q2NV9JKS
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT2B (Homo sapiens (Human))	BDBM50346564 (CHEMBL1795607) Show SMILES Cc1cnc2sn(-c3ccc(Oc4ccccc4)cc3)c(=O)c2c1 Show InChI InChI=1S/C19H14N2O2S/c1-13-11-17-18(20-12-13)24-21(19(17)22)14-7-9-16(10-8-14)23-15-5-3-2-4-6-15/h2-12H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.29E+4	n/a	n/a	n/a	n/a	n/a	n/a
Albert-Ludwigs-University of Freiburg Curated by ChEMBL					Assay Description Inhibition of histone acetylase activity of human recombinant PCAF expressed in Escherichia coli using biotinylated oligopeptide sequences from histo...				Bioorg Med Chem 19: 3678-89 (2011) Article DOI: 10.1016/j.bmc.2011.01.063 BindingDB Entry DOI: 10.7270/Q2NV9JKS
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT2B (Homo sapiens (Human))	BDBM50346556 (CHEMBL1795611) Show SMILES Cc1cnc2sn(-c3ccc(cc3)[N+]([O-])=O)c(=O)c2c1 Show InChI InChI=1S/C13H9N3O3S/c1-8-6-11-12(14-7-8)20-15(13(11)17)9-2-4-10(5-3-9)16(18)19/h2-7H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.53E+4	n/a	n/a	n/a	n/a	n/a	n/a
Albert-Ludwigs-University of Freiburg Curated by ChEMBL					Assay Description Inhibition of histone acetylase activity of human recombinant PCAF expressed in Escherichia coli using biotinylated oligopeptide sequences from histo...				Bioorg Med Chem 19: 3678-89 (2011) Article DOI: 10.1016/j.bmc.2011.01.063 BindingDB Entry DOI: 10.7270/Q2NV9JKS
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT2B (Homo sapiens (Human))	BDBM50346558 (CHEMBL1795606) Show SMILES [O-][N+](=O)c1ccc(cc1)-n1sc2ncc(cc2c1=O)[N+]([O-])=O Show InChI InChI=1S/C12H6N4O5S/c17-12-10-5-9(16(20)21)6-13-11(10)22-14(12)7-1-3-8(4-2-7)15(18)19/h1-6H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.58E+4	n/a	n/a	n/a	n/a	n/a	n/a
Albert-Ludwigs-University of Freiburg Curated by ChEMBL					Assay Description Inhibition of histone acetylase activity of human recombinant PCAF expressed in Escherichia coli using biotinylated oligopeptide sequences from histo...				Bioorg Med Chem 19: 3678-89 (2011) Article DOI: 10.1016/j.bmc.2011.01.063 BindingDB Entry DOI: 10.7270/Q2NV9JKS
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT2B (Homo sapiens (Human))	BDBM50346566 (CHEMBL1795610) Show SMILES CCCCc1ccc(cc1)-n1sc2ncccc2c1=O Show InChI InChI=1S/C16H16N2OS/c1-2-3-5-12-7-9-13(10-8-12)18-16(19)14-6-4-11-17-15(14)20-18/h4,6-11H,2-3,5H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.59E+4	n/a	n/a	n/a	n/a	n/a	n/a
Albert-Ludwigs-University of Freiburg Curated by ChEMBL					Assay Description Inhibition of histone acetylase activity of human recombinant PCAF expressed in Escherichia coli using biotinylated oligopeptide sequences from histo...				Bioorg Med Chem 19: 3678-89 (2011) Article DOI: 10.1016/j.bmc.2011.01.063 BindingDB Entry DOI: 10.7270/Q2NV9JKS
					More data for this Ligand-Target Pair
Histone acetyltransferase KAT2B (Homo sapiens (Human))	BDBM50346573 (CHEMBL1795618) Show SMILES Clc1ccc(Cn2sc3ncccc3c2=O)cc1 Show InChI InChI=1S/C13H9ClN2OS/c14-10-5-3-9(4-6-10)8-16-13(17)11-2-1-7-15-12(11)18-16/h1-7H,8H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.75E+4	n/a	n/a	n/a	n/a	n/a	n/a
Albert-Ludwigs-University of Freiburg Curated by ChEMBL					Assay Description Inhibition of histone acetylase activity of human recombinant PCAF expressed in Escherichia coli using biotinylated oligopeptide sequences from histo...				Bioorg Med Chem 19: 3678-89 (2011) Article DOI: 10.1016/j.bmc.2011.01.063 BindingDB Entry DOI: 10.7270/Q2NV9JKS
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50373747 (CHEMBL270905) Show SMILES Ic1ccc2c3C(CC(=O)Oc3ccc2c1)c1ccccc1 |w:6.18| Show InChI InChI=1S/C19H13IO2/c20-14-7-8-15-13(10-14)6-9-17-19(15)16(11-18(21)22-17)12-4-2-1-3-5-12/h1-10,16H,11H2	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.95E+4	n/a	n/a	n/a	n/a	n/a	n/a
Albert-Ludwigs-Universit£t Freiburg Curated by ChEMBL					Assay Description Inhibition of human recombinant Sirt2 expressed in Escherichia coli BL21 by fluorescent deacetylase assay				J Med Chem 51: 1203-13 (2008) Article DOI: 10.1021/jm700972e BindingDB Entry DOI: 10.7270/Q22N534Q
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50373759 (CHEMBL272461) Show SMILES Fc1ccc(cc1F)C1CC(=O)Oc2ccc3cc(Br)ccc3c12 |w:8.8| Show InChI InChI=1S/C19H11BrF2O2/c20-12-3-4-13-10(7-12)2-6-17-19(13)14(9-18(23)24-17)11-1-5-15(21)16(22)8-11/h1-8,14H,9H2	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.97E+4	n/a	n/a	n/a	n/a	n/a	n/a
Albert-Ludwigs-Universit£t Freiburg Curated by ChEMBL					Assay Description Inhibition of human recombinant Sirt2 expressed in Escherichia coli BL21 by fluorescent deacetylase assay				J Med Chem 51: 1203-13 (2008) Article DOI: 10.1021/jm700972e BindingDB Entry DOI: 10.7270/Q22N534Q
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50373750 (CHEMBL406803) Show SMILES Cc1ccc2c3C(CC(=O)Oc3ccc2c1)c1cccc(c1)C(N)=O |w:6.18| Show InChI InChI=1S/C21H17NO3/c1-12-5-7-16-14(9-12)6-8-18-20(16)17(11-19(23)25-18)13-3-2-4-15(10-13)21(22)24/h2-10,17H,11H2,1H3,(H2,22,24)	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Albert-Ludwigs-Universit£t Freiburg Curated by ChEMBL					Assay Description Inhibition of human recombinant Sirt2 expressed in Escherichia coli BL21 by fluorescent deacetylase assay				J Med Chem 51: 1203-13 (2008) Article DOI: 10.1021/jm700972e BindingDB Entry DOI: 10.7270/Q22N534Q
					More data for this Ligand-Target Pair

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