Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Phosphotransferase pUL97 (Human cytomegalovirus) | BDBM50330328 ((Z)-2-amino-9-((2,2-bis(hydroxymethyl)cyclopropyli...) | UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Michigan Curated by ChEMBL | Assay Description Inhibition of Human cytomegalovirus pUL97 assessed as inhibition of phosphorylation of 100 to 1000 uM cyclopropavir | Antimicrob Agents Chemother 54: 3093-8 (2010) Article DOI: 10.1128/AAC.00468-10 BindingDB Entry DOI: 10.7270/Q25D8S36 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1) | BDBM50134782 (6-amino-9-[(Z)-(2-{[(1,2,3,3-tetrahydroxy-1,2,3-tr...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 320 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wayne State University School of Medicine Curated by ChEMBL | Assay Description Inhibitory activity against HIV-1 Reverse transcriptase wild-type (RT wt) | J Med Chem 46: 4799-802 (2003) Article DOI: 10.1021/jm030048y BindingDB Entry DOI: 10.7270/Q2D50NQB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1) | BDBM50164644 (2',3'-Dideoxyadenosine Triphosphate (Ddatp) | 2',3...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 500 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wayne State University School of Medicine Curated by ChEMBL | Assay Description Inhibitory activity against HIV-1 reverse transcriptase (RT M184V) | J Med Chem 46: 4799-802 (2003) Article DOI: 10.1021/jm030048y BindingDB Entry DOI: 10.7270/Q2D50NQB | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1) | BDBM50164644 (2',3'-Dideoxyadenosine Triphosphate (Ddatp) | 2',3...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 510 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wayne State University School of Medicine Curated by ChEMBL | Assay Description Inhibitory activity against HIV-1 Reverse transcriptase wild-type (RT wt) | J Med Chem 46: 4799-802 (2003) Article DOI: 10.1021/jm030048y BindingDB Entry DOI: 10.7270/Q2D50NQB | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1) | BDBM50164644 (2',3'-Dideoxyadenosine Triphosphate (Ddatp) | 2',3...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wayne State University School of Medicine Curated by ChEMBL | Assay Description Inhibitory activity against HIV-1 reverse transcriptase (RT M184I) | J Med Chem 46: 4799-802 (2003) Article DOI: 10.1021/jm030048y BindingDB Entry DOI: 10.7270/Q2D50NQB | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1) | BDBM50134782 (6-amino-9-[(Z)-(2-{[(1,2,3,3-tetrahydroxy-1,2,3-tr...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wayne State University School of Medicine Curated by ChEMBL | Assay Description Inhibitory activity against HIV-1 reverse transcriptase (RT M184V) | J Med Chem 46: 4799-802 (2003) Article DOI: 10.1021/jm030048y BindingDB Entry DOI: 10.7270/Q2D50NQB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1) | BDBM50134782 (6-amino-9-[(Z)-(2-{[(1,2,3,3-tetrahydroxy-1,2,3-tr...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wayne State University School of Medicine Curated by ChEMBL | Assay Description Inhibitory activity against HIV-1 reverse transcriptase (RT M184I) | J Med Chem 46: 4799-802 (2003) Article DOI: 10.1021/jm030048y BindingDB Entry DOI: 10.7270/Q2D50NQB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1) | BDBM50134783 (6-amino-9-[(E)-(2-{[(1,2,3,3-tetrahydroxy-1,2,3-tr...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wayne State University School of Medicine Curated by ChEMBL | Assay Description Inhibitory activity against HIV-1 Reverse transcriptase wild-type (RT wt) | J Med Chem 46: 4799-802 (2003) Article DOI: 10.1021/jm030048y BindingDB Entry DOI: 10.7270/Q2D50NQB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1) | BDBM50134783 (6-amino-9-[(E)-(2-{[(1,2,3,3-tetrahydroxy-1,2,3-tr...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 5.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wayne State University School of Medicine Curated by ChEMBL | Assay Description Inhibitory activity against HIV-1 reverse transcriptase (RT M184V) | J Med Chem 46: 4799-802 (2003) Article DOI: 10.1021/jm030048y BindingDB Entry DOI: 10.7270/Q2D50NQB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1) | BDBM50134783 (6-amino-9-[(E)-(2-{[(1,2,3,3-tetrahydroxy-1,2,3-tr...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 7.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wayne State University School of Medicine Curated by ChEMBL | Assay Description Inhibitory activity against HIV-1 reverse transcriptase (RT M184I) | J Med Chem 46: 4799-802 (2003) Article DOI: 10.1021/jm030048y BindingDB Entry DOI: 10.7270/Q2D50NQB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1) | BDBM50002692 ((AZT) 1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | DrugBank Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wayne State University School of Medicine Curated by ChEMBL | Assay Description Inhibitory concentration of the compound against human immunodeficiency virus type 1 (HIV-1 strain IIIB RT) reverse transcriptase was determined by t... | J Med Chem 41: 10-23 (1998) Article DOI: 10.1021/jm9705723 BindingDB Entry DOI: 10.7270/Q2VX0FM4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1) | BDBM50002692 ((AZT) 1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | DrugBank Article PubMed | n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
Wayne State University School of Medicine Curated by ChEMBL | Assay Description Inhibitory concentration of the compound against human immunodeficiency virus type 1 (HIV-1 strain IIIB RT) reverse transcriptase was determined by t... | J Med Chem 41: 10-23 (1998) Article DOI: 10.1021/jm9705723 BindingDB Entry DOI: 10.7270/Q2VX0FM4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1) | BDBM50061986 (CHEMBL305612 | [2-(6-Amino-purin-9-ylmethylene)-cy...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
Wayne State University School of Medicine Curated by ChEMBL | Assay Description Inhibitory concentration of the compound against human immunodeficiency virus type 1 (HIV-1 strain IIIB RT) reverse transcriptase was determined by t... | J Med Chem 41: 10-23 (1998) Article DOI: 10.1021/jm9705723 BindingDB Entry DOI: 10.7270/Q2VX0FM4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1) | BDBM50061987 (2-Amino-9-[2-hydroxymethyl-cycloprop-(Z)-ylideneme...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wayne State University School of Medicine Curated by ChEMBL | Assay Description Inhibitory concentration of the compound against human immunodeficiency virus type 1 (HIV-1 strain IIIB RT) reverse transcriptase was determined by t... | J Med Chem 41: 10-23 (1998) Article DOI: 10.1021/jm9705723 BindingDB Entry DOI: 10.7270/Q2VX0FM4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1) | BDBM50061983 (2-Amino-9-[2-hydroxymethyl-cycloprop-(E)-ylideneme...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wayne State University School of Medicine Curated by ChEMBL | Assay Description Inhibitory concentration of the compound against human immunodeficiency virus type 1 (HIV-1 strain IIIB RT) reverse transcriptase was determined by t... | J Med Chem 41: 10-23 (1998) Article DOI: 10.1021/jm9705723 BindingDB Entry DOI: 10.7270/Q2VX0FM4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1) | BDBM50061984 (CHEMBL74478 | {(2E)-2-[(6-amino-9H-purin-9-yl)meth...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wayne State University School of Medicine Curated by ChEMBL | Assay Description Inhibitory concentration of the compound against human immunodeficiency virus type 1 (HIV-1 strain IIIB RT) reverse transcriptase was determined by t... | J Med Chem 41: 10-23 (1998) Article DOI: 10.1021/jm9705723 BindingDB Entry DOI: 10.7270/Q2VX0FM4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1) | BDBM50061986 (CHEMBL305612 | [2-(6-Amino-purin-9-ylmethylene)-cy...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wayne State University School of Medicine Curated by ChEMBL | Assay Description Inhibitory concentration of the compound against human immunodeficiency virus type 1 (HIV-1 strain IIIB RT) reverse transcriptase was determined by t... | J Med Chem 41: 10-23 (1998) Article DOI: 10.1021/jm9705723 BindingDB Entry DOI: 10.7270/Q2VX0FM4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1) | BDBM50061987 (2-Amino-9-[2-hydroxymethyl-cycloprop-(Z)-ylideneme...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wayne State University School of Medicine Curated by ChEMBL | Assay Description Inhibitory concentration of the compound against human immunodeficiency virus type 1 (HIV-1 strain IIIB RT) reverse transcriptase was determined by t... | J Med Chem 41: 10-23 (1998) Article DOI: 10.1021/jm9705723 BindingDB Entry DOI: 10.7270/Q2VX0FM4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1) | BDBM50061983 (2-Amino-9-[2-hydroxymethyl-cycloprop-(E)-ylideneme...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wayne State University School of Medicine Curated by ChEMBL | Assay Description Inhibitory concentration of the compound against human immunodeficiency virus type 1 (HIV-1 strain IIIB RT) reverse transcriptase was determined by t... | J Med Chem 41: 10-23 (1998) Article DOI: 10.1021/jm9705723 BindingDB Entry DOI: 10.7270/Q2VX0FM4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1) | BDBM50061985 (CHEMBL76121 | {2-[1-(2-Amino-6-chloro-purin-9-yl)-...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Wayne State University School of Medicine Curated by ChEMBL | Assay Description Inhibitory concentration of the compound against human immunodeficiency virus type 1 (HIV-1 strain IIIB RT) reverse transcriptase was determined by t... | J Med Chem 41: 10-23 (1998) Article DOI: 10.1021/jm9705723 BindingDB Entry DOI: 10.7270/Q2VX0FM4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1) | BDBM50061982 (CHEMBL75950 | {2-[1-(2-Amino-6-chloro-purin-7-yl)-...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Wayne State University School of Medicine Curated by ChEMBL | Assay Description Inhibitory concentration of the compound against human immunodeficiency virus type 1 (HIV-1 strain IIIB RT) reverse transcriptase was determined by t... | J Med Chem 41: 10-23 (1998) Article DOI: 10.1021/jm9705723 BindingDB Entry DOI: 10.7270/Q2VX0FM4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1) | BDBM50061984 (CHEMBL74478 | {(2E)-2-[(6-amino-9H-purin-9-yl)meth...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Wayne State University School of Medicine Curated by ChEMBL | Assay Description Inhibitory concentration of the compound against human immunodeficiency virus type 1 (HIV-1 strain IIIB RT) reverse transcriptase was determined by t... | J Med Chem 41: 10-23 (1998) Article DOI: 10.1021/jm9705723 BindingDB Entry DOI: 10.7270/Q2VX0FM4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1) | BDBM50059015 (CHEMBL69158 | [(E)-5-(6-Amino-purin-9-yl)-pent-3-e...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 9.00E+3 | n/a | n/a | n/a | n/a |
Wayne State University School of Medicine Curated by ChEMBL | Assay Description tested for its inhibition of HIV-1 reverse transcriptase. | J Med Chem 40: 2191-5 (1997) Article DOI: 10.1021/jm970069q BindingDB Entry DOI: 10.7270/Q2KW5F5C | |||||||||||
More data for this Ligand-Target Pair |