Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Interleukin-1 beta (Homo sapiens (Human)) | BDBM531223 ((R)-2-(4-Methyl-6-((1-methylpiperidin-3-yl)amino)p...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.400 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Monocytic THP-1 cells (ATCC: TIB-202) were maintained according to providers' instructions in RPMI media (RPMI/Hepes+10% fetal bovine serum+Sodiu... | Citation and Details BindingDB Entry DOI: 10.7270/Q2JD50Z5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase D1 (Homo sapiens (Human)) | BDBM50324297 (4-(1-Piperazin-1-yl[2,6]naphthyridin-3-yl)pyridin-...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.400 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research Curated by ChEMBL | Assay Description Inhibition of PKD1 by TR-FRET assay | J Med Chem 53: 5400-21 (2010) Article DOI: 10.1021/jm100075z BindingDB Entry DOI: 10.7270/Q2T153T9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-1 beta (Homo sapiens (Human)) | BDBM531296 (US11208399, Example 53) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.400 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Monocytic THP-1 cells (ATCC: TIB-202) were maintained according to providers' instructions in RPMI media (RPMI/Hepes+10% fetal bovine serum+Sodiu... | Citation and Details BindingDB Entry DOI: 10.7270/Q2JD50Z5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase D1 (Homo sapiens (Human)) | BDBM50324315 (CHEMBL1214998 | Cyclohexyl-[4-(1-piperazin-1-yl[2,...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research Curated by ChEMBL | Assay Description Inhibition of PKD1 by TR-FRET assay | J Med Chem 53: 5400-21 (2010) Article DOI: 10.1021/jm100075z BindingDB Entry DOI: 10.7270/Q2T153T9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-1 beta (Homo sapiens (Human)) | BDBM531253 (US11208399, Example 12) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Monocytic THP-1 cells (ATCC: TIB-202) were maintained according to providers' instructions in RPMI media (RPMI/Hepes+10% fetal bovine serum+Sodiu... | Citation and Details BindingDB Entry DOI: 10.7270/Q2JD50Z5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-1 beta (Homo sapiens (Human)) | BDBM531331 (US11208399, Example 82) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.700 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Monocytic THP-1 cells (ATCC: TIB-202) were maintained according to providers' instructions in RPMI media (RPMI/Hepes+10% fetal bovine serum+Sodiu... | Citation and Details BindingDB Entry DOI: 10.7270/Q2JD50Z5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-1 beta (Homo sapiens (Human)) | BDBM531332 (US11208399, Example 83a) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.800 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Monocytic THP-1 cells (ATCC: TIB-202) were maintained according to providers' instructions in RPMI media (RPMI/Hepes+10% fetal bovine serum+Sodiu... | Citation and Details BindingDB Entry DOI: 10.7270/Q2JD50Z5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-1 beta (Homo sapiens (Human)) | BDBM531288 (US11208399, Example 47) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.800 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Monocytic THP-1 cells (ATCC: TIB-202) were maintained according to providers' instructions in RPMI media (RPMI/Hepes+10% fetal bovine serum+Sodiu... | Citation and Details BindingDB Entry DOI: 10.7270/Q2JD50Z5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-1 beta (Homo sapiens (Human)) | BDBM531289 (US11208399, Example 48) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.800 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Monocytic THP-1 cells (ATCC: TIB-202) were maintained according to providers' instructions in RPMI media (RPMI/Hepes+10% fetal bovine serum+Sodiu... | Citation and Details BindingDB Entry DOI: 10.7270/Q2JD50Z5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-1 beta (Homo sapiens (Human)) | BDBM531220 ((R)-2-(6-((1-Ethylpiperidin-3-yl)amino)pyridazin-3...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.800 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Monocytic THP-1 cells (ATCC: TIB-202) were maintained according to providers' instructions in RPMI media (RPMI/Hepes+10% fetal bovine serum+Sodiu... | Citation and Details BindingDB Entry DOI: 10.7270/Q2JD50Z5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-1 beta (Homo sapiens (Human)) | BDBM531319 (US11208399, Example 71) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.800 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Monocytic THP-1 cells (ATCC: TIB-202) were maintained according to providers' instructions in RPMI media (RPMI/Hepes+10% fetal bovine serum+Sodiu... | Citation and Details BindingDB Entry DOI: 10.7270/Q2JD50Z5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-1 beta (Homo sapiens (Human)) | BDBM531230 (US11208399, Example 6) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.900 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Monocytic THP-1 cells (ATCC: TIB-202) were maintained according to providers' instructions in RPMI media (RPMI/Hepes+10% fetal bovine serum+Sodiu... | Citation and Details BindingDB Entry DOI: 10.7270/Q2JD50Z5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase D1 (Homo sapiens (Human)) | BDBM50324306 (1-[3-(2-Cyclohexylaminopyridin-4-yl)[2,6]naphthyri...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research Curated by ChEMBL | Assay Description Inhibition of PKD1 by TR-FRET assay | J Med Chem 53: 5400-21 (2010) Article DOI: 10.1021/jm100075z BindingDB Entry DOI: 10.7270/Q2T153T9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase D1 (Homo sapiens (Human)) | BDBM50324298 (CHEMBL1215712 | {4-[1-(4-Isobutylpiperazin-1-yl)[2...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research Curated by ChEMBL | Assay Description Inhibition of PKD1 by TR-FRET assay | J Med Chem 53: 5400-21 (2010) Article DOI: 10.1021/jm100075z BindingDB Entry DOI: 10.7270/Q2T153T9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase D1 (Homo sapiens (Human)) | BDBM50324305 (CHEMBL1214711 | N-(2-(pyrrolidin-1-yl)ethyl)-1-(3-...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research Curated by ChEMBL | Assay Description Inhibition of PKD1 by TR-FRET assay | J Med Chem 53: 5400-21 (2010) Article DOI: 10.1021/jm100075z BindingDB Entry DOI: 10.7270/Q2T153T9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase D1 (Homo sapiens (Human)) | BDBM50324296 (1-[3-(2-Cyclohexylaminopyridin-4-yl)[2,6]naphthyri...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research Curated by ChEMBL | Assay Description Inhibition of PKD1 by TR-FRET assay | J Med Chem 53: 5400-21 (2010) Article DOI: 10.1021/jm100075z BindingDB Entry DOI: 10.7270/Q2T153T9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase D1 (Homo sapiens (Human)) | BDBM50324314 (1-{3-[2-(Tetrahydropyran-4-ylamino)pyridin-4-yl][2...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research Curated by ChEMBL | Assay Description Inhibition of PKD1 by TR-FRET assay | J Med Chem 53: 5400-21 (2010) Article DOI: 10.1021/jm100075z BindingDB Entry DOI: 10.7270/Q2T153T9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-1 beta (Homo sapiens (Human)) | BDBM531254 (US11208399, Example 13) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Monocytic THP-1 cells (ATCC: TIB-202) were maintained according to providers' instructions in RPMI media (RPMI/Hepes+10% fetal bovine serum+Sodiu... | Citation and Details BindingDB Entry DOI: 10.7270/Q2JD50Z5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-1 beta (Homo sapiens (Human)) | BDBM531337 (3-Methyl-2-(6-(((1R,2R,5R)-8-methyl-8-azabicyclo[3...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Monocytic THP-1 cells (ATCC: TIB-202) were maintained according to providers' instructions in RPMI media (RPMI/Hepes+10% fetal bovine serum+Sodiu... | Citation and Details BindingDB Entry DOI: 10.7270/Q2JD50Z5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-1 beta (Homo sapiens (Human)) | BDBM531252 (US11208399, Example 11) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Monocytic THP-1 cells (ATCC: TIB-202) were maintained according to providers' instructions in RPMI media (RPMI/Hepes+10% fetal bovine serum+Sodiu... | Citation and Details BindingDB Entry DOI: 10.7270/Q2JD50Z5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-1 beta (Homo sapiens (Human)) | BDBM531291 (US11208399, Example 49) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Monocytic THP-1 cells (ATCC: TIB-202) were maintained according to providers' instructions in RPMI media (RPMI/Hepes+10% fetal bovine serum+Sodiu... | Citation and Details BindingDB Entry DOI: 10.7270/Q2JD50Z5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-1 beta (Homo sapiens (Human)) | BDBM531354 (2-(6-(((3S, 5S)-5-Fluoro-1-methylpiperidin-3-yl)am...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Monocytic THP-1 cells (ATCC: TIB-202) were maintained according to providers' instructions in RPMI media (RPMI/Hepes+10% fetal bovine serum+Sodiu... | Citation and Details BindingDB Entry DOI: 10.7270/Q2JD50Z5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-1 beta (Homo sapiens (Human)) | BDBM531339 (2-(6-(((1S,2S,5S)-8-(2-Hydroxyethyl)-8-azabicyclo[...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Monocytic THP-1 cells (ATCC: TIB-202) were maintained according to providers' instructions in RPMI media (RPMI/Hepes+10% fetal bovine serum+Sodiu... | Citation and Details BindingDB Entry DOI: 10.7270/Q2JD50Z5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-1 beta (Homo sapiens (Human)) | BDBM531232 (US11208399, Example 7) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Monocytic THP-1 cells (ATCC: TIB-202) were maintained according to providers' instructions in RPMI media (RPMI/Hepes+10% fetal bovine serum+Sodiu... | Citation and Details BindingDB Entry DOI: 10.7270/Q2JD50Z5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-1 beta (Homo sapiens (Human)) | BDBM531364 ((R)-2-(6-((1-Ethylpiperidin-3-yl)amino)-5-methylpy...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Monocytic THP-1 cells (ATCC: TIB-202) were maintained according to providers' instructions in RPMI media (RPMI/Hepes+10% fetal bovine serum+Sodiu... | Citation and Details BindingDB Entry DOI: 10.7270/Q2JD50Z5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human)) | BDBM50320214 (3-(7-amino-3-(4-(4-methylpiperazin-1-yl)phenyl)pyr...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institute of Biomedical Research Curated by ChEMBL | Assay Description Inhibition of SRC | Bioorg Med Chem Lett 20: 3628-31 (2010) Article DOI: 10.1016/j.bmcl.2010.04.112 BindingDB Entry DOI: 10.7270/Q2XP754D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase D1 (Homo sapiens (Human)) | BDBM50324313 (1-{3-[2-(Tetrahydropyran-4-ylamino)pyridin-4-yl][2...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research Curated by ChEMBL | Assay Description Inhibition of PKD1 by TR-FRET assay | J Med Chem 53: 5400-21 (2010) Article DOI: 10.1021/jm100075z BindingDB Entry DOI: 10.7270/Q2T153T9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase D1 (Homo sapiens (Human)) | BDBM50324294 (CHEMBL1215643 | Cyclohexyl-{4-[1-(4-cyclopropylmet...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research Curated by ChEMBL | Assay Description Inhibition of PKD1 by TR-FRET assay | J Med Chem 53: 5400-21 (2010) Article DOI: 10.1021/jm100075z BindingDB Entry DOI: 10.7270/Q2T153T9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C eta type (Homo sapiens (Human)) | BDBM50391897 (CHEMBL2147537) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research Curated by ChEMBL | Assay Description Inhibition of recombinant human PKCeta assessed as [33P]-ATP incorporation into tridecapeptide substrate after 60 mins by scintillation proximity ass... | Bioorg Med Chem Lett 21: 7367-72 (2011) Article DOI: 10.1016/j.bmcl.2011.10.025 BindingDB Entry DOI: 10.7270/Q22J6CZ4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase D1 (Homo sapiens (Human)) | BDBM50324312 (1-{3-[2-(Tetrahydropyran-4-ylamino)pyridin-4-yl][2...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research Curated by ChEMBL | Assay Description Inhibition of PKD1 by TR-FRET assay | J Med Chem 53: 5400-21 (2010) Article DOI: 10.1021/jm100075z BindingDB Entry DOI: 10.7270/Q2T153T9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase D1 (Homo sapiens (Human)) | BDBM50324309 (1-{3-[2-(Tetrahydropyran-4-ylamino)pyridin-4-yl][2...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research Curated by ChEMBL | Assay Description Inhibition of PKD1 by TR-FRET assay | J Med Chem 53: 5400-21 (2010) Article DOI: 10.1021/jm100075z BindingDB Entry DOI: 10.7270/Q2T153T9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase D1 (Homo sapiens (Human)) | BDBM50324292 (CHEMBL1215641 | Cyclohexyl-{4-[1-(4-methylpiperazi...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research Curated by ChEMBL | Assay Description Inhibition of PKD1 by TR-FRET assay | J Med Chem 53: 5400-21 (2010) Article DOI: 10.1021/jm100075z BindingDB Entry DOI: 10.7270/Q2T153T9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-1 beta (Homo sapiens (Human)) | BDBM531292 (US11208399, Example 50) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Monocytic THP-1 cells (ATCC: TIB-202) were maintained according to providers' instructions in RPMI media (RPMI/Hepes+10% fetal bovine serum+Sodiu... | Citation and Details BindingDB Entry DOI: 10.7270/Q2JD50Z5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-1 beta (Homo sapiens (Human)) | BDBM531323 (US11208399, Example 74) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.60 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Monocytic THP-1 cells (ATCC: TIB-202) were maintained according to providers' instructions in RPMI media (RPMI/Hepes+10% fetal bovine serum+Sodiu... | Citation and Details BindingDB Entry DOI: 10.7270/Q2JD50Z5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-1 beta (Homo sapiens (Human)) | BDBM531293 (US11208399, Example 51) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.60 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Monocytic THP-1 cells (ATCC: TIB-202) were maintained according to providers' instructions in RPMI media (RPMI/Hepes+10% fetal bovine serum+Sodiu... | Citation and Details BindingDB Entry DOI: 10.7270/Q2JD50Z5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-1 beta (Homo sapiens (Human)) | BDBM531282 (US11208399, Example 41) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Monocytic THP-1 cells (ATCC: TIB-202) were maintained according to providers' instructions in RPMI media (RPMI/Hepes+10% fetal bovine serum+Sodiu... | Citation and Details BindingDB Entry DOI: 10.7270/Q2JD50Z5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase D1 (Homo sapiens (Human)) | BDBM50324291 (CHEMBL1215640 | Cyclohexyl-{4-[1-((cis-3,5-dimethy...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research Curated by ChEMBL | Assay Description Inhibition of PKD1 by TR-FRET assay | J Med Chem 53: 5400-21 (2010) Article DOI: 10.1021/jm100075z BindingDB Entry DOI: 10.7270/Q2T153T9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase D1 (Homo sapiens (Human)) | BDBM50324304 (1-[3-(2-Cyclohexylaminopyridin-4-yl)[2,6]naphthyri...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research Curated by ChEMBL | Assay Description Inhibition of PKD1 by TR-FRET assay | J Med Chem 53: 5400-21 (2010) Article DOI: 10.1021/jm100075z BindingDB Entry DOI: 10.7270/Q2T153T9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase D1 (Homo sapiens (Human)) | BDBM50324310 (1-{3-[2-(Tetrahydropyran-4-ylamino)pyridin-4-yl][2...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research Curated by ChEMBL | Assay Description Inhibition of PKD1 by TR-FRET assay | J Med Chem 53: 5400-21 (2010) Article DOI: 10.1021/jm100075z BindingDB Entry DOI: 10.7270/Q2T153T9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-1 beta (Homo sapiens (Human)) | BDBM531224 ((R)-3-Methyl-2-(5-methyl-6-((1-methylpiperidin-3-y...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Monocytic THP-1 cells (ATCC: TIB-202) were maintained according to providers' instructions in RPMI media (RPMI/Hepes+10% fetal bovine serum+Sodiu... | Citation and Details BindingDB Entry DOI: 10.7270/Q2JD50Z5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human)) | BDBM118314 (US8653092, 82) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description Test of Lipid Kinase Activity: The kinase reaction is performed in a final volume of 50 μl per well of a half area COSTAR, 96 well plate. The fi... | US Patent US8653092 (2014) BindingDB Entry DOI: 10.7270/Q2M61HXZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase D1 (Homo sapiens (Human)) | BDBM50324311 (1-{3-[2-(Tetrahydropyran-4-ylamino)pyridin-4-yl][2...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research Curated by ChEMBL | Assay Description Inhibition of PKD1 by TR-FRET assay | J Med Chem 53: 5400-21 (2010) Article DOI: 10.1021/jm100075z BindingDB Entry DOI: 10.7270/Q2T153T9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human)) | BDBM118301 (US8653092, 69) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description Test of Lipid Kinase Activity: The kinase reaction is performed in a final volume of 50 μl per well of a half area COSTAR, 96 well plate. The fi... | US Patent US8653092 (2014) BindingDB Entry DOI: 10.7270/Q2M61HXZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human)) | BDBM118303 (US8653092, 71) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description Test of Lipid Kinase Activity: The kinase reaction is performed in a final volume of 50 μl per well of a half area COSTAR, 96 well plate. The fi... | US Patent US8653092 (2014) BindingDB Entry DOI: 10.7270/Q2M61HXZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-1 beta (Homo sapiens (Human)) | BDBM531286 (US11208399, Example 45) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Monocytic THP-1 cells (ATCC: TIB-202) were maintained according to providers' instructions in RPMI media (RPMI/Hepes+10% fetal bovine serum+Sodiu... | Citation and Details BindingDB Entry DOI: 10.7270/Q2JD50Z5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-1 beta (Homo sapiens (Human)) | BDBM531279 (US11208399, Example 39) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Monocytic THP-1 cells (ATCC: TIB-202) were maintained according to providers' instructions in RPMI media (RPMI/Hepes+10% fetal bovine serum+Sodiu... | Citation and Details BindingDB Entry DOI: 10.7270/Q2JD50Z5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-1 beta (Homo sapiens (Human)) | BDBM531350 (2-(6-(((R)-1-((S)-2-Hydroxypropyl)piperidin-3-yl)a...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Monocytic THP-1 cells (ATCC: TIB-202) were maintained according to providers' instructions in RPMI media (RPMI/Hepes+10% fetal bovine serum+Sodiu... | Citation and Details BindingDB Entry DOI: 10.7270/Q2JD50Z5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-1 beta (Homo sapiens (Human)) | BDBM531318 (US11208399, Example 70) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Monocytic THP-1 cells (ATCC: TIB-202) were maintained according to providers' instructions in RPMI media (RPMI/Hepes+10% fetal bovine serum+Sodiu... | Citation and Details BindingDB Entry DOI: 10.7270/Q2JD50Z5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-1 beta (Homo sapiens (Human)) | BDBM531351 (2-(6-(((R)-1-((R)-2-Hydroxypropyl)piperidin-3-yl)a...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.60 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Monocytic THP-1 cells (ATCC: TIB-202) were maintained according to providers' instructions in RPMI media (RPMI/Hepes+10% fetal bovine serum+Sodiu... | Citation and Details BindingDB Entry DOI: 10.7270/Q2JD50Z5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C alpha type (Homo sapiens (Human)) | BDBM3033 (3-{23-methyl-14-oxo-3,13,23-triazahexacyclo[14.7.0...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 3.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research Curated by ChEMBL | Assay Description Inhibition of PKCalpha by TR-FRET assay | J Med Chem 53: 5400-21 (2010) Article DOI: 10.1021/jm100075z BindingDB Entry DOI: 10.7270/Q2T153T9 | |||||||||||
More data for this Ligand-Target Pair |
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