Compile Data Set for Download or QSAR

Found 318 hits Enz. Inhib. hit(s) with Target = 'Transcription activator BRG1'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transcription activator BRG1 (Homo sapiens (Human))	BDBM50443232 (CHEMBL3086883) Show SMILES Cc1cc(N=Nc2ccc(cc2)S(=O)(=O)Nc2ccccn2)c(N)cc1O |w:4.3| Show InChI InChI=1S/C18H17N5O3S/c1-12-10-16(15(19)11-17(12)24)22-21-13-5-7-14(8-6-13)27(25,26)23-18-4-2-3-9-20-18/h2-11,24H,19H2,1H3,(H,20,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	7.97E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Displacement of fluorescein-labeled MS239 from recombinant human SMARCA4 bromodomain after 1 hr by fluorescence anisotropy assay				J Med Chem 56: 9251-64 (2013) Article DOI: 10.1021/jm401334s BindingDB Entry DOI: 10.7270/Q2ZW1NCF
					More data for this Ligand-Target Pair
Transcription activator BRG1 [1448-1575] (Homo sapiens (Human))	BDBM394450 (2-(6-amino-5-(8-(5- | US10308614, Example 51) Show SMILES Nc1nnc(cc1N1CC2CCC(C1)N2c1cncc(F)c1)-c1ccccc1O |TLB:15:14:10.11:7.8.13| Show InChI InChI=1S/C21H21FN6O/c22-13-7-16(10-24-9-13)28-14-5-6-15(28)12-27(11-14)19-8-18(25-26-21(19)23)17-3-1-2-4-20(17)29/h1-4,7-10,14-15,29H,5-6,11-12H2,(H2,23,26)	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.40	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research					Assay Description His-BRG1 (A1448-S1575; Swiss Prot P51532; mhhhhhhgslvpr\gsAEKLSPNPP NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNH KYRSLNDLEKDVMLLCQNA...				J Med Chem 52: 2255-64 (2009) BindingDB Entry DOI: 10.7270/Q26112NJ
					More data for this Ligand-Target Pair
Transcription activator BRG1 [1448-1575] (Homo sapiens (Human))	BDBM394468 (2-(6-amino-5-(8- | US10308614, Example 69) Show SMILES Nc1nnc(cc1N1CC2CCC(C1)N2c1ccccn1)-c1ccccc1O |TLB:15:14:7.8.13:10.11| Show InChI InChI=1S/C21H22N6O/c22-21-18(11-17(24-25-21)16-5-1-2-6-19(16)28)26-12-14-8-9-15(13-26)27(14)20-7-3-4-10-23-20/h1-7,10-11,14-15,28H,8-9,12-13H2,(H2,22,25)	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.90	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research					Assay Description His-BRG1 (A1448-S1575; Swiss Prot P51532; mhhhhhhgslvpr\gsAEKLSPNPP NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNH KYRSLNDLEKDVMLLCQNA...				J Med Chem 52: 2255-64 (2009) BindingDB Entry DOI: 10.7270/Q26112NJ
					More data for this Ligand-Target Pair
Transcription activator BRG1 [1448-1575] (Homo sapiens (Human))	BDBM394474 (2-(6-amino-5-(8-(5- | US10308614, Example 75) Show SMILES Nc1nnc(cc1N1CC2CCC(C1)N2c1ccc(F)cn1)-c1ccccc1O |TLB:15:14:7.8.13:10.11| Show InChI InChI=1S/C21H21FN6O/c22-13-5-8-20(24-10-13)28-14-6-7-15(28)12-27(11-14)18-9-17(25-26-21(18)23)16-3-1-2-4-19(16)29/h1-5,8-10,14-15,29H,6-7,11-12H2,(H2,23,26)	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research					Assay Description His-BRG1 (A1448-S1575; Swiss Prot P51532; mhhhhhhgslvpr\gsAEKLSPNPP NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNH KYRSLNDLEKDVMLLCQNA...				J Med Chem 52: 2255-64 (2009) BindingDB Entry DOI: 10.7270/Q26112NJ
					More data for this Ligand-Target Pair
Transcription activator BRG1 [1448-1575] (Homo sapiens (Human))	BDBM394469 (2-(6-amino-5-(8-(pyridin- | US10308614, Example 70) Show SMILES Nc1nnc(cc1N1CC2CCC(C1)N2c1cccnc1)-c1ccccc1O |TLB:15:14:7.8.13:10.11| Show InChI InChI=1S/C21H22N6O/c22-21-19(10-18(24-25-21)17-5-1-2-6-20(17)28)26-12-15-7-8-16(13-26)27(15)14-4-3-9-23-11-14/h1-6,9-11,15-16,28H,7-8,12-13H2,(H2,22,25)	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.10	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research					Assay Description His-BRG1 (A1448-S1575; Swiss Prot P51532; mhhhhhhgslvpr\gsAEKLSPNPP NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNH KYRSLNDLEKDVMLLCQNA...				J Med Chem 52: 2255-64 (2009) BindingDB Entry DOI: 10.7270/Q26112NJ
					More data for this Ligand-Target Pair
Transcription activator BRG1 [1448-1575] (Homo sapiens (Human))	BDBM394462 (2-(6-amino-5-(8-phenyl-3,8- | US10308614, Example ...) Show SMILES Nc1nnc(cc1N1CC2CCC(C1)N2c1ccccc1)-c1ccccc1O |TLB:15:14:7.8.13:10.11| Show InChI InChI=1S/C22H23N5O/c23-22-20(12-19(24-25-22)18-8-4-5-9-21(18)28)26-13-16-10-11-17(14-26)27(16)15-6-2-1-3-7-15/h1-9,12,16-17,28H,10-11,13-14H2,(H2,23,25)	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.30	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research					Assay Description His-BRG1 (A1448-S1575; Swiss Prot P51532; mhhhhhhgslvpr\gsAEKLSPNPP NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNH KYRSLNDLEKDVMLLCQNA...				J Med Chem 52: 2255-64 (2009) BindingDB Entry DOI: 10.7270/Q26112NJ
					More data for this Ligand-Target Pair
Transcription activator BRG1 [1448-1575] (Homo sapiens (Human))	BDBM394446 (2-(6-amino-5-(8-(2- | US10308614, Example 47) Show SMILES Nc1nnc(cc1N1CC2CCC(C1)N2c1ccnc(F)c1)-c1ccccc1O Show InChI InChI=1S/C21H21FN6O/c22-20-9-13(7-8-24-20)28-14-5-6-15(28)12-27(11-14)18-10-17(25-26-21(18)23)16-3-1-2-4-19(16)29/h1-4,7-10,14-15,29H,5-6,11-12H2,(H2,23,26)	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research					Assay Description His-BRG1 (A1448-S1575; Swiss Prot P51532; mhhhhhhgslvpr\gsAEKLSPNPP NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNH KYRSLNDLEKDVMLLCQNA...				J Med Chem 52: 2255-64 (2009) BindingDB Entry DOI: 10.7270/Q26112NJ
					More data for this Ligand-Target Pair
Transcription activator BRG1 (Homo sapiens (Human))	BDBM50469320 (CHEMBL4293567) Show SMILES OCc1cnc(Cl)cc1NC(=O)Nc1cc(ns1)C(F)F Show InChI InChI=1S/C11H9ClF2N4O2S/c12-8-1-6(5(4-19)3-15-8)16-11(20)17-9-2-7(10(13)14)18-21-9/h1-3,10,19H,4H2,(H2,15,16,17,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of recombinant His6-tagged BRG1 ATPase-SnAC (658 to 1361 residues) (unknown origin) expressed in insect sf9 cells preincubated for 5 mins ...				J Med Chem 61: 10155-10172 (2018) Article DOI: 10.1021/acs.jmedchem.8b01318 BindingDB Entry DOI: 10.7270/Q2TH8QDB
					More data for this Ligand-Target Pair
Transcription activator BRG1 [1448-1575] (Homo sapiens (Human))	BDBM394470 (2-(6-amino-5-(8- | US10308614, Example 71) Show SMILES Nc1nnc(cc1N1CC2CCC(C1)N2c1ncccn1)-c1ccccc1O |TLB:15:14:7.8.13:10.11| Show InChI InChI=1S/C20H21N7O/c21-19-17(10-16(24-25-19)15-4-1-2-5-18(15)28)26-11-13-6-7-14(12-26)27(13)20-22-8-3-9-23-20/h1-5,8-10,13-14,28H,6-7,11-12H2,(H2,21,25)	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research					Assay Description His-BRG1 (A1448-S1575; Swiss Prot P51532; mhhhhhhgslvpr\gsAEKLSPNPP NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNH KYRSLNDLEKDVMLLCQNA...				J Med Chem 52: 2255-64 (2009) BindingDB Entry DOI: 10.7270/Q26112NJ
					More data for this Ligand-Target Pair
Transcription activator BRG1 (Homo sapiens (Human))	BDBM50469331 (CHEMBL4282980) Show SMILES Nc1cnc(F)cc1NC(=O)Nc1cc(ns1)C(F)F Show InChI InChI=1S/C10H8F3N5OS/c11-7-1-5(4(14)3-15-7)16-10(19)17-8-2-6(9(12)13)18-20-8/h1-3,9H,14H2,(H2,15,16,17,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of recombinant His6-tagged BRG1 ATPase-SnAC (658 to 1361 residues) (unknown origin) expressed in insect sf9 cells preincubated for 5 mins ...				J Med Chem 61: 10155-10172 (2018) Article DOI: 10.1021/acs.jmedchem.8b01318 BindingDB Entry DOI: 10.7270/Q2TH8QDB
					More data for this Ligand-Target Pair
Transcription activator BRG1 (Homo sapiens (Human))	BDBM50469324 (CHEMBL4286345) Show SMILES Nc1cnc(Cl)cc1NC(=O)Nc1cc(ns1)C(F)F Show InChI InChI=1S/C10H8ClF2N5OS/c11-7-1-5(4(14)3-15-7)16-10(19)17-8-2-6(9(12)13)18-20-8/h1-3,9H,14H2,(H2,15,16,17,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of recombinant His6-tagged BRG1 ATPase-SnAC (658 to 1361 residues) (unknown origin) expressed in insect sf9 cells preincubated for 5 mins ...				J Med Chem 61: 10155-10172 (2018) Article DOI: 10.1021/acs.jmedchem.8b01318 BindingDB Entry DOI: 10.7270/Q2TH8QDB
					More data for this Ligand-Target Pair
Transcription activator BRG1 (Homo sapiens (Human))	BDBM50469330 (CHEMBL4295096) Show SMILES OCc1cnc(F)cc1NC(=O)Nc1cc(ns1)C(F)F Show InChI InChI=1S/C11H9F3N4O2S/c12-8-1-6(5(4-19)3-15-8)16-11(20)17-9-2-7(10(13)14)18-21-9/h1-3,10,19H,4H2,(H2,15,16,17,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of recombinant His6-tagged BRG1 ATPase-SnAC (658 to 1361 residues) (unknown origin) expressed in insect sf9 cells preincubated for 5 mins ...				J Med Chem 61: 10155-10172 (2018) Article DOI: 10.1021/acs.jmedchem.8b01318 BindingDB Entry DOI: 10.7270/Q2TH8QDB
					More data for this Ligand-Target Pair
Transcription activator BRG1 (Homo sapiens (Human))	BDBM50469329 (CHEMBL4278436) Show SMILES FC(F)c1cc(NC(=O)Nc2ccnc(Cl)c2)sn1 Show InChI InChI=1S/C10H7ClF2N4OS/c11-7-3-5(1-2-14-7)15-10(18)16-8-4-6(9(12)13)17-19-8/h1-4,9H,(H2,14,15,16,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of recombinant His6-tagged BRG1 ATPase-SnAC (658 to 1361 residues) (unknown origin) expressed in insect sf9 cells preincubated for 5 mins ...				J Med Chem 61: 10155-10172 (2018) Article DOI: 10.1021/acs.jmedchem.8b01318 BindingDB Entry DOI: 10.7270/Q2TH8QDB
					More data for this Ligand-Target Pair
Transcription activator BRG1 [1448-1575] (Homo sapiens (Human))	BDBM394589 (2-(6-amino-5-(1-(1- | US10308614, Example 192) Show SMILES CC(c1ccccc1)n1cnc(c1)-c1cc(nnc1N)-c1ccccc1O Show InChI InChI=1S/C21H19N5O/c1-14(15-7-3-2-4-8-15)26-12-19(23-13-26)17-11-18(24-25-21(17)22)16-9-5-6-10-20(16)27/h2-14,27H,1H3,(H2,22,25)	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.30	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research					Assay Description His-BRG1 (A1448-S1575; Swiss Prot P51532; mhhhhhhgslvpr\gsAEKLSPNPP NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNH KYRSLNDLEKDVMLLCQNA...				J Med Chem 52: 2255-64 (2009) BindingDB Entry DOI: 10.7270/Q26112NJ
					More data for this Ligand-Target Pair
Transcription activator BRG1 [1448-1575] (Homo sapiens (Human))	BDBM394476 (2-(6-amino-5-(8-(thiazol- | US10308614, Example 77) Show SMILES Nc1nnc(cc1N1CC2CCC(C1)N2c1nccs1)-c1ccccc1O |TLB:15:14:7.8.13:10.11| Show InChI InChI=1S/C19H20N6OS/c20-18-16(9-15(22-23-18)14-3-1-2-4-17(14)26)24-10-12-5-6-13(11-24)25(12)19-21-7-8-27-19/h1-4,7-9,12-13,26H,5-6,10-11H2,(H2,20,23)	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.5	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research					Assay Description His-BRG1 (A1448-S1575; Swiss Prot P51532; mhhhhhhgslvpr\gsAEKLSPNPP NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNH KYRSLNDLEKDVMLLCQNA...				J Med Chem 52: 2255-64 (2009) BindingDB Entry DOI: 10.7270/Q26112NJ
					More data for this Ligand-Target Pair
Transcription activator BRG1 [1448-1575] (Homo sapiens (Human))	BDBM394585 (2-(6-amino-5-(1-(1- | US10308614, Example 188) Show SMILES CC(c1ccccc1)n1cc(cn1)-c1cc(nnc1N)-c1ccccc1O Show InChI InChI=1S/C21H19N5O/c1-14(15-7-3-2-4-8-15)26-13-16(12-23-26)18-11-19(24-25-21(18)22)17-9-5-6-10-20(17)27/h2-14,27H,1H3,(H2,22,25)	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.60	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research					Assay Description His-BRG1 (A1448-S1575; Swiss Prot P51532; mhhhhhhgslvpr\gsAEKLSPNPP NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNH KYRSLNDLEKDVMLLCQNA...				J Med Chem 52: 2255-64 (2009) BindingDB Entry DOI: 10.7270/Q26112NJ
					More data for this Ligand-Target Pair
Transcription activator BRG1 [1448-1575] (Homo sapiens (Human))	BDBM394475 (2-(6-amino-5-(8-(4- | US10308614, Example 76) Show SMILES Nc1nnc(cc1N1CC2CCC(C1)N2c1ccc(F)cc1)-c1ccccc1O |TLB:15:14:7.8.13:10.11| Show InChI InChI=1S/C22H22FN5O/c23-14-5-7-15(8-6-14)28-16-9-10-17(28)13-27(12-16)20-11-19(25-26-22(20)24)18-3-1-2-4-21(18)29/h1-8,11,16-17,29H,9-10,12-13H2,(H2,24,26)	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.70	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research					Assay Description His-BRG1 (A1448-S1575; Swiss Prot P51532; mhhhhhhgslvpr\gsAEKLSPNPP NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNH KYRSLNDLEKDVMLLCQNA...				J Med Chem 52: 2255-64 (2009) BindingDB Entry DOI: 10.7270/Q26112NJ
					More data for this Ligand-Target Pair
Transcription activator BRG1 [1448-1575] (Homo sapiens (Human))	BDBM394427 ((trans-4a,8a)-2-(3-amino-6- | US10308614, Example ...) Show SMILES Nc1nnc(cc1N1CC[C@@]2(O)CCCC[C@@H]2C1)-c1ccccc1O |r| Show InChI InChI=1S/C19H24N4O2/c20-18-16(11-15(21-22-18)14-6-1-2-7-17(14)24)23-10-9-19(25)8-4-3-5-13(19)12-23/h1-2,6-7,11,13,24-25H,3-5,8-10,12H2,(H2,20,22)/t13-,19+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8.40	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research					Assay Description His-BRG1 (A1448-S1575; Swiss Prot P51532; mhhhhhhgslvpr\gsAEKLSPNPP NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNH KYRSLNDLEKDVMLLCQNA...				J Med Chem 52: 2255-64 (2009) BindingDB Entry DOI: 10.7270/Q26112NJ
					More data for this Ligand-Target Pair
Transcription activator BRG1 (Homo sapiens (Human))	BDBM50469325 (CHEMBL4294655) Show SMILES FC(F)(F)c1cc(NC(=O)Nc2ccnc(Cl)c2)sn1 Show InChI InChI=1S/C10H6ClF3N4OS/c11-7-3-5(1-2-15-7)16-9(19)17-8-4-6(18-20-8)10(12,13)14/h1-4H,(H2,15,16,17,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of recombinant His6-tagged BRG1 ATPase-SnAC (658 to 1361 residues) (unknown origin) expressed in insect sf9 cells preincubated for 5 mins ...				J Med Chem 61: 10155-10172 (2018) Article DOI: 10.1021/acs.jmedchem.8b01318 BindingDB Entry DOI: 10.7270/Q2TH8QDB
					More data for this Ligand-Target Pair
Transcription activator BRG1 [1448-1575] (Homo sapiens (Human))	BDBM394528 (1-(4-(3-amino-6-(2- | US10308614, Example 129) Show SMILES CC1CN(CCN1C(=O)C(C)(C)C)c1cc(nnc1N)-c1ccccc1O Show InChI InChI=1S/C20H27N5O2/c1-13-12-24(9-10-25(13)19(27)20(2,3)4)16-11-15(22-23-18(16)21)14-7-5-6-8-17(14)26/h5-8,11,13,26H,9-10,12H2,1-4H3,(H2,21,23)	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10.4	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research					Assay Description His-BRG1 (A1448-S1575; Swiss Prot P51532; mhhhhhhgslvpr\gsAEKLSPNPP NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNH KYRSLNDLEKDVMLLCQNA...				J Med Chem 52: 2255-64 (2009) BindingDB Entry DOI: 10.7270/Q26112NJ
					More data for this Ligand-Target Pair
Transcription activator BRG1 [1448-1575] (Homo sapiens (Human))	BDBM394473 (2-(6-amino-5-((1R,4R)-5- | US10308614, Example 74) Show SMILES Nc1nnc(cc1N1C[C@H]2C[C@@H]1CN2c1ccccn1)-c1ccccc1O |r| Show InChI InChI=1S/C20H20N6O/c21-20-17(10-16(23-24-20)15-5-1-2-6-18(15)27)25-11-14-9-13(25)12-26(14)19-7-3-4-8-22-19/h1-8,10,13-14,27H,9,11-12H2,(H2,21,24)/t13-,14-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10.6	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research					Assay Description His-BRG1 (A1448-S1575; Swiss Prot P51532; mhhhhhhgslvpr\gsAEKLSPNPP NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNH KYRSLNDLEKDVMLLCQNA...				J Med Chem 52: 2255-64 (2009) BindingDB Entry DOI: 10.7270/Q26112NJ
					More data for this Ligand-Target Pair
Transcription activator BRG1 [1448-1575] (Homo sapiens (Human))	BDBM394449 (2-(6-amino-5-(8- | US10308614, Example 50) Show SMILES Nc1nnc(cc1N1CC2CCC(C1)N2c1cnccn1)-c1ccccc1O |TLB:15:14:10.11:7.8.13| Show InChI InChI=1S/C20H21N7O/c21-20-17(9-16(24-25-20)15-3-1-2-4-18(15)28)26-11-13-5-6-14(12-26)27(13)19-10-22-7-8-23-19/h1-4,7-10,13-14,28H,5-6,11-12H2,(H2,21,25)	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10.6	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research					Assay Description His-BRG1 (A1448-S1575; Swiss Prot P51532; mhhhhhhgslvpr\gsAEKLSPNPP NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNH KYRSLNDLEKDVMLLCQNA...				J Med Chem 52: 2255-64 (2009) BindingDB Entry DOI: 10.7270/Q26112NJ
					More data for this Ligand-Target Pair
Transcription activator BRG1 [1448-1575] (Homo sapiens (Human))	BDBM394485 (Enantiomer 1 and Enantiomer 2 of (trans-4a,8a)-2-(...) Show SMILES Nc1nnc(cc1N1CC[C@]2(O)CCCC[C@@H]2C1)-c1ccccc1O |r| Show InChI InChI=1S/C19H24N4O2/c20-18-16(11-15(21-22-18)14-6-1-2-7-17(14)24)23-10-9-19(25)8-4-3-5-13(19)12-23/h1-2,6-7,11,13,24-25H,3-5,8-10,12H2,(H2,20,22)/t13-,19-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research					Assay Description His-BRG1 (A1448-S1575; Swiss Prot P51532; mhhhhhhgslvpr\gsAEKLSPNPP NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNH KYRSLNDLEKDVMLLCQNA...				J Med Chem 52: 2255-64 (2009) BindingDB Entry DOI: 10.7270/Q26112NJ
					More data for this Ligand-Target Pair
Transcription activator BRG1 [1448-1575] (Homo sapiens (Human))	BDBM394441 (1-(3-amino-6-(2- | US10308614, Example 42) Show SMILES Nc1nnc(cc1N1CCC(O)(CC1)c1ccccc1)-c1ccccc1O Show InChI InChI=1S/C21H22N4O2/c22-20-18(14-17(23-24-20)16-8-4-5-9-19(16)26)25-12-10-21(27,11-13-25)15-6-2-1-3-7-15/h1-9,14,26-27H,10-13H2,(H2,22,24)	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11.3	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research					Assay Description His-BRG1 (A1448-S1575; Swiss Prot P51532; mhhhhhhgslvpr\gsAEKLSPNPP NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNH KYRSLNDLEKDVMLLCQNA...				J Med Chem 52: 2255-64 (2009) BindingDB Entry DOI: 10.7270/Q26112NJ
					More data for this Ligand-Target Pair
Transcription activator BRG1 [1448-1575] (Homo sapiens (Human))	BDBM394461 ((4-(3-amino-6-(2- | US10308614, Example 62) Show SMILES CC1CN(CCN1C(=O)c1ccccc1)c1cc(nnc1N)-c1ccccc1O Show InChI InChI=1S/C22H23N5O2/c1-15-14-26(11-12-27(15)22(29)16-7-3-2-4-8-16)19-13-18(24-25-21(19)23)17-9-5-6-10-20(17)28/h2-10,13,15,28H,11-12,14H2,1H3,(H2,23,25)	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11.7	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research					Assay Description His-BRG1 (A1448-S1575; Swiss Prot P51532; mhhhhhhgslvpr\gsAEKLSPNPP NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNH KYRSLNDLEKDVMLLCQNA...				J Med Chem 52: 2255-64 (2009) BindingDB Entry DOI: 10.7270/Q26112NJ
					More data for this Ligand-Target Pair
Transcription activator BRG1 [1448-1575] (Homo sapiens (Human))	BDBM394595 (2-(6-amino-5-(trans-2-phenylcyclopropyl)pyridazin-...) Show SMILES Nc1nnc(cc1[C@@H]1C[C@H]1c1ccccc1)-c1ccccc1O |r| Show InChI InChI=1S/C19H17N3O/c20-19-16(15-10-14(15)12-6-2-1-3-7-12)11-17(21-22-19)13-8-4-5-9-18(13)23/h1-9,11,14-15,23H,10H2,(H2,20,22)/t14-,15+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12.1	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research					Assay Description His-BRG1 (A1448-S1575; Swiss Prot P51532; mhhhhhhgslvpr\gsAEKLSPNPP NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNH KYRSLNDLEKDVMLLCQNA...				J Med Chem 52: 2255-64 (2009) BindingDB Entry DOI: 10.7270/Q26112NJ
					More data for this Ligand-Target Pair
Transcription activator BRG1 [1448-1575] (Homo sapiens (Human))	BDBM394575 (2-(6-amino-5-(2- | US10308614, Example 178) Show SMILES CC(COc1cc(nnc1N)-c1ccccc1O)c1ccccc1 Show InChI InChI=1S/C19H19N3O2/c1-13(14-7-3-2-4-8-14)12-24-18-11-16(21-22-19(18)20)15-9-5-6-10-17(15)23/h2-11,13,23H,12H2,1H3,(H2,20,22)	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12.2	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research					Assay Description His-BRG1 (A1448-S1575; Swiss Prot P51532; mhhhhhhgslvpr\gsAEKLSPNPP NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNH KYRSLNDLEKDVMLLCQNA...				J Med Chem 52: 2255-64 (2009) BindingDB Entry DOI: 10.7270/Q26112NJ
					More data for this Ligand-Target Pair
Transcription activator BRG1 [1448-1575] (Homo sapiens (Human))	BDBM394537 ((4-(3-amino-6-(2- | US10308614, Example 138) Show SMILES CC1CN(CCN1C(=O)c1cncs1)c1cc(nnc1N)-c1ccccc1O Show InChI InChI=1S/C19H20N6O2S/c1-12-10-24(6-7-25(12)19(27)17-9-21-11-28-17)15-8-14(22-23-18(15)20)13-4-2-3-5-16(13)26/h2-5,8-9,11-12,26H,6-7,10H2,1H3,(H2,20,23)	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12.6	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research					Assay Description His-BRG1 (A1448-S1575; Swiss Prot P51532; mhhhhhhgslvpr\gsAEKLSPNPP NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNH KYRSLNDLEKDVMLLCQNA...				J Med Chem 52: 2255-64 (2009) BindingDB Entry DOI: 10.7270/Q26112NJ
					More data for this Ligand-Target Pair
Transcription activator BRG1 [1448-1575] (Homo sapiens (Human))	BDBM394584 (2-(6-amino-5-(1-methyl- | US10308614, Example 187) Show SMILES Cn1cc(cn1)-c1cc(nnc1N)-c1ccccc1O Show InChI InChI=1S/C14H13N5O/c1-19-8-9(7-16-19)11-6-12(17-18-14(11)15)10-4-2-3-5-13(10)20/h2-8,20H,1H3,(H2,15,18)	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12.8	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research					Assay Description His-BRG1 (A1448-S1575; Swiss Prot P51532; mhhhhhhgslvpr\gsAEKLSPNPP NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNH KYRSLNDLEKDVMLLCQNA...				J Med Chem 52: 2255-64 (2009) BindingDB Entry DOI: 10.7270/Q26112NJ
					More data for this Ligand-Target Pair
Transcription activator BRG1 [1448-1575] (Homo sapiens (Human))	BDBM394605 (2-(6-amino-5-cyclohexylpyridazin-3-yl)phenol | US1...) Show SMILES Nc1nnc(cc1C1CCCCC1)-c1ccccc1O Show InChI InChI=1S/C16H19N3O/c17-16-13(11-6-2-1-3-7-11)10-14(18-19-16)12-8-4-5-9-15(12)20/h4-5,8-11,20H,1-3,6-7H2,(H2,17,19)	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	14.5	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research					Assay Description His-BRG1 (A1448-S1575; Swiss Prot P51532; mhhhhhhgslvpr\gsAEKLSPNPP NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNH KYRSLNDLEKDVMLLCQNA...				J Med Chem 52: 2255-64 (2009) BindingDB Entry DOI: 10.7270/Q26112NJ
					More data for this Ligand-Target Pair
Transcription activator BRG1 [1448-1575] (Homo sapiens (Human))	BDBM394571 (2-(6-amino-5- | US10308614, Example 174) Show SMILES Nc1nnc(cc1OCCc1ccccc1)-c1ccccc1O Show InChI InChI=1S/C18H17N3O2/c19-18-17(23-11-10-13-6-2-1-3-7-13)12-15(20-21-18)14-8-4-5-9-16(14)22/h1-9,12,22H,10-11H2,(H2,19,21)	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	14.8	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research					Assay Description His-BRG1 (A1448-S1575; Swiss Prot P51532; mhhhhhhgslvpr\gsAEKLSPNPP NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNH KYRSLNDLEKDVMLLCQNA...				J Med Chem 52: 2255-64 (2009) BindingDB Entry DOI: 10.7270/Q26112NJ
					More data for this Ligand-Target Pair
Transcription activator BRG1 [1448-1575] (Homo sapiens (Human))	BDBM394458 (1-(3-amino-6-(2- | US10308614, Example 59) Show SMILES Nc1nnc(cc1N1CCCC(O)(C1)c1ccccc1)-c1ccccc1O Show InChI InChI=1S/C21H22N4O2/c22-20-18(13-17(23-24-20)16-9-4-5-10-19(16)26)25-12-6-11-21(27,14-25)15-7-2-1-3-8-15/h1-5,7-10,13,26-27H,6,11-12,14H2,(H2,22,24)	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15.8	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research					Assay Description His-BRG1 (A1448-S1575; Swiss Prot P51532; mhhhhhhgslvpr\gsAEKLSPNPP NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNH KYRSLNDLEKDVMLLCQNA...				J Med Chem 52: 2255-64 (2009) BindingDB Entry DOI: 10.7270/Q26112NJ
					More data for this Ligand-Target Pair
Transcription activator BRG1 [1448-1575] (Homo sapiens (Human))	BDBM394580 (2-(6-amino-5-((1- | US10308614, Example 183) Show SMILES Nc1nnc(cc1OC1CCCN(C1)c1ccccc1)-c1ccccc1O Show InChI InChI=1S/C21H22N4O2/c22-21-20(13-18(23-24-21)17-10-4-5-11-19(17)26)27-16-9-6-12-25(14-16)15-7-2-1-3-8-15/h1-5,7-8,10-11,13,16,26H,6,9,12,14H2,(H2,22,24)	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17.2	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research					Assay Description His-BRG1 (A1448-S1575; Swiss Prot P51532; mhhhhhhgslvpr\gsAEKLSPNPP NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNH KYRSLNDLEKDVMLLCQNA...				J Med Chem 52: 2255-64 (2009) BindingDB Entry DOI: 10.7270/Q26112NJ
					More data for this Ligand-Target Pair
Transcription activator BRG1 [1448-1575] (Homo sapiens (Human))	BDBM394427 ((trans-4a,8a)-2-(3-amino-6- | US10308614, Example ...) Show SMILES Nc1nnc(cc1N1CC[C@@]2(O)CCCC[C@@H]2C1)-c1ccccc1O |r| Show InChI InChI=1S/C19H24N4O2/c20-18-16(11-15(21-22-18)14-6-1-2-7-17(14)24)23-10-9-19(25)8-4-3-5-13(19)12-23/h1-2,6-7,11,13,24-25H,3-5,8-10,12H2,(H2,20,22)/t13-,19+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17.2	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research					Assay Description His-BRG1 (A1448-S1575; Swiss Prot P51532; mhhhhhhgslvpr\gsAEKLSPNPP NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNH KYRSLNDLEKDVMLLCQNA...				J Med Chem 52: 2255-64 (2009) BindingDB Entry DOI: 10.7270/Q26112NJ
					More data for this Ligand-Target Pair
Transcription activator BRG1 [1448-1575] (Homo sapiens (Human))	BDBM394424 (2-(6-amino-5-(4-methyl- | US10308614, Example 25) Show SMILES CN1CCOC2(CCN(CC2)c2cc(nnc2N)-c2ccccc2O)C1 Show InChI InChI=1S/C19H25N5O2/c1-23-10-11-26-19(13-23)6-8-24(9-7-19)16-12-15(21-22-18(16)20)14-4-2-3-5-17(14)25/h2-5,12,25H,6-11,13H2,1H3,(H2,20,22)	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17.6	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research					Assay Description His-BRG1 (A1448-S1575; Swiss Prot P51532; mhhhhhhgslvpr\gsAEKLSPNPP NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNH KYRSLNDLEKDVMLLCQNA...				J Med Chem 52: 2255-64 (2009) BindingDB Entry DOI: 10.7270/Q26112NJ
					More data for this Ligand-Target Pair
Transcription activator BRG1 [1448-1575] (Homo sapiens (Human))	BDBM394508 (2-(6-amino-5-(3-methyl- | US10308614, Example 109) Show SMILES CC1CN(CCN1S(=O)(=O)c1ccccc1)c1cc(nnc1N)-c1ccccc1O Show InChI InChI=1S/C21H23N5O3S/c1-15-14-25(11-12-26(15)30(28,29)16-7-3-2-4-8-16)19-13-18(23-24-21(19)22)17-9-5-6-10-20(17)27/h2-10,13,15,27H,11-12,14H2,1H3,(H2,22,24)	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17.6	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research					Assay Description His-BRG1 (A1448-S1575; Swiss Prot P51532; mhhhhhhgslvpr\gsAEKLSPNPP NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNH KYRSLNDLEKDVMLLCQNA...				J Med Chem 52: 2255-64 (2009) BindingDB Entry DOI: 10.7270/Q26112NJ
					More data for this Ligand-Target Pair
Transcription activator BRG1 [1448-1575] (Homo sapiens (Human))	BDBM394587 (2-(6-amino-5- | US10308614, Example 190) Show SMILES Nc1nnc(cc1C1CC1)-c1ccccc1O Show InChI InChI=1S/C13H13N3O/c14-13-10(8-5-6-8)7-11(15-16-13)9-3-1-2-4-12(9)17/h1-4,7-8,17H,5-6H2,(H2,14,16)	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17.6	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research					Assay Description His-BRG1 (A1448-S1575; Swiss Prot P51532; mhhhhhhgslvpr\gsAEKLSPNPP NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNH KYRSLNDLEKDVMLLCQNA...				J Med Chem 52: 2255-64 (2009) BindingDB Entry DOI: 10.7270/Q26112NJ
					More data for this Ligand-Target Pair
Transcription activator BRG1 [1448-1575] (Homo sapiens (Human))	BDBM394456 (2-(6-amino-5-(3- | US10308614, Example 57) Show SMILES Nc1nnc(cc1N1CC(C1)Oc1ccccc1)-c1ccccc1O Show InChI InChI=1S/C19H18N4O2/c20-19-17(10-16(21-22-19)15-8-4-5-9-18(15)24)23-11-14(12-23)25-13-6-2-1-3-7-13/h1-10,14,24H,11-12H2,(H2,20,22)	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17.7	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research					Assay Description His-BRG1 (A1448-S1575; Swiss Prot P51532; mhhhhhhgslvpr\gsAEKLSPNPP NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNH KYRSLNDLEKDVMLLCQNA...				J Med Chem 52: 2255-64 (2009) BindingDB Entry DOI: 10.7270/Q26112NJ
					More data for this Ligand-Target Pair
Transcription activator BRG1 [1448-1575] (Homo sapiens (Human))	BDBM394492 ((S)-2-(6-amino-5-(3-methyl-4-((1-methyl-1H-imidazo...) Show SMILES C[C@H]1CN(CCN1Cc1nccn1C)c1cc(nnc1N)-c1ccccc1O |r| Show InChI InChI=1S/C20H25N7O/c1-14-12-27(10-9-26(14)13-19-22-7-8-25(19)2)17-11-16(23-24-20(17)21)15-5-3-4-6-18(15)28/h3-8,11,14,28H,9-10,12-13H2,1-2H3,(H2,21,24)/t14-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	18.5	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research					Assay Description His-BRG1 (A1448-S1575; Swiss Prot P51532; mhhhhhhgslvpr\gsAEKLSPNPP NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNH KYRSLNDLEKDVMLLCQNA...				J Med Chem 52: 2255-64 (2009) BindingDB Entry DOI: 10.7270/Q26112NJ
					More data for this Ligand-Target Pair
Transcription activator BRG1 [1448-1575] (Homo sapiens (Human))	BDBM394621 (2-(6-amino-5-((1,4-trans)-4-methylcyclohexyl)pyrid...) Show SMILES C[C@H]1CC[C@@H](CC1)c1cc(nnc1N)-c1ccccc1O |r,wU:1.0,wD:4.7,(1.33,-5.78,;1.33,-4.23,;,-3.47,;,-1.93,;1.33,-1.15,;2.67,-1.93,;2.67,-3.47,;1.33,.38,;,1.15,;,2.69,;1.33,3.47,;2.67,2.69,;2.67,1.15,;4,.38,;-1.33,3.47,;-2.67,2.69,;-4,3.47,;-4,5,;-2.67,5.78,;-1.33,5,;,5.78,)| Show InChI InChI=1S/C17H21N3O/c1-11-6-8-12(9-7-11)14-10-15(19-20-17(14)18)13-4-2-3-5-16(13)21/h2-5,10-12,21H,6-9H2,1H3,(H2,18,20)/t11-,12-	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research					Assay Description His-BRG1 (A1448-S1575; Swiss Prot P51532; mhhhhhhgslvpr\gsAEKLSPNPP NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNH KYRSLNDLEKDVMLLCQNA...				J Med Chem 52: 2255-64 (2009) BindingDB Entry DOI: 10.7270/Q26112NJ
					More data for this Ligand-Target Pair
Transcription activator BRG1 [1448-1575] (Homo sapiens (Human))	BDBM394481 (Enantiomer 1 and Enantiomer 2 of 2-(6-amino-5-(4-(...) Show SMILES C[C@@H](N1CCN(CC1)c1cc(nnc1N)-c1ccccc1O)c1ccccc1 |r| Show InChI InChI=1S/C22H25N5O/c1-16(17-7-3-2-4-8-17)26-11-13-27(14-12-26)20-15-19(24-25-22(20)23)18-9-5-6-10-21(18)28/h2-10,15-16,28H,11-14H2,1H3,(H2,23,25)/t16-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	19.1	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research					Assay Description His-BRG1 (A1448-S1575; Swiss Prot P51532; mhhhhhhgslvpr\gsAEKLSPNPP NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNH KYRSLNDLEKDVMLLCQNA...				J Med Chem 52: 2255-64 (2009) BindingDB Entry DOI: 10.7270/Q26112NJ
					More data for this Ligand-Target Pair
Transcription activator BRG1 [1448-1575] (Homo sapiens (Human))	BDBM394442 (2-(6-amino-5-(8- | US10308614, Example 43) Show SMILES Nc1nnc(cc1N1CC2CCC(C1)N2c1cncnc1)-c1ccccc1O |TLB:15:14:7.8.13:10.11| Show InChI InChI=1S/C20H21N7O/c21-20-18(7-17(24-25-20)16-3-1-2-4-19(16)28)26-10-13-5-6-14(11-26)27(13)15-8-22-12-23-9-15/h1-4,7-9,12-14,28H,5-6,10-11H2,(H2,21,25)	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	19.3	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research					Assay Description His-BRG1 (A1448-S1575; Swiss Prot P51532; mhhhhhhgslvpr\gsAEKLSPNPP NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNH KYRSLNDLEKDVMLLCQNA...				J Med Chem 52: 2255-64 (2009) BindingDB Entry DOI: 10.7270/Q26112NJ
					More data for this Ligand-Target Pair
Transcription activator BRG1 [1448-1575] (Homo sapiens (Human))	BDBM394510 (2-(6-amino-5-(4- | US10308614, Example 111) Show SMILES CC1CN(CCN1S(=O)(=O)C1CC1)c1cc(nnc1N)-c1ccccc1O Show InChI InChI=1S/C18H23N5O3S/c1-12-11-22(8-9-23(12)27(25,26)13-6-7-13)16-10-15(20-21-18(16)19)14-4-2-3-5-17(14)24/h2-5,10,12-13,24H,6-9,11H2,1H3,(H2,19,21)	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	19.7	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research					Assay Description His-BRG1 (A1448-S1575; Swiss Prot P51532; mhhhhhhgslvpr\gsAEKLSPNPP NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNH KYRSLNDLEKDVMLLCQNA...				J Med Chem 52: 2255-64 (2009) BindingDB Entry DOI: 10.7270/Q26112NJ
					More data for this Ligand-Target Pair
Transcription activator BRG1 [1448-1575] (Homo sapiens (Human))	BDBM394525 ((3-(3-amino-6-(2- | US10308614, Example 126) Show SMILES Nc1nnc(cc1N1CC2CCC(C1)N2C(=O)c1cncs1)-c1ccccc1O |TLB:15:14:7.8.13:10.11| Show InChI InChI=1S/C20H20N6O2S/c21-19-16(7-15(23-24-19)14-3-1-2-4-17(14)27)25-9-12-5-6-13(10-25)26(12)20(28)18-8-22-11-29-18/h1-4,7-8,11-13,27H,5-6,9-10H2,(H2,21,24)	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20.3	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research					Assay Description His-BRG1 (A1448-S1575; Swiss Prot P51532; mhhhhhhgslvpr\gsAEKLSPNPP NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNH KYRSLNDLEKDVMLLCQNA...				J Med Chem 52: 2255-64 (2009) BindingDB Entry DOI: 10.7270/Q26112NJ
					More data for this Ligand-Target Pair
Transcription activator BRG1 [1448-1575] (Homo sapiens (Human))	BDBM394619 (2-(6-amino-5-(1-benzyl-1,2,3,6-tetrahydropyridin-4...) Show SMILES Nc1nnc(cc1C1=CCN(Cc2ccccc2)CC1)-c1ccccc1O |t:8| Show InChI InChI=1S/C22H22N4O/c23-22-19(14-20(24-25-22)18-8-4-5-9-21(18)27)17-10-12-26(13-11-17)15-16-6-2-1-3-7-16/h1-10,14,27H,11-13,15H2,(H2,23,25)	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20.5	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research					Assay Description His-BRG1 (A1448-S1575; Swiss Prot P51532; mhhhhhhgslvpr\gsAEKLSPNPP NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNH KYRSLNDLEKDVMLLCQNA...				J Med Chem 52: 2255-64 (2009) BindingDB Entry DOI: 10.7270/Q26112NJ
					More data for this Ligand-Target Pair
Transcription activator BRG1 [1448-1575] (Homo sapiens (Human))	BDBM394542 ((4-(3-amino-6-(2- | US10308614, Example 143) Show SMILES Nc1nnc(cc1N1CCN(C(CO)C1)C(=O)c1cncs1)-c1ccccc1O Show InChI InChI=1S/C19H20N6O3S/c20-18-15(7-14(22-23-18)13-3-1-2-4-16(13)27)24-5-6-25(12(9-24)10-26)19(28)17-8-21-11-29-17/h1-4,7-8,11-12,26-27H,5-6,9-10H2,(H2,20,23)	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20.6	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research					Assay Description His-BRG1 (A1448-S1575; Swiss Prot P51532; mhhhhhhgslvpr\gsAEKLSPNPP NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNH KYRSLNDLEKDVMLLCQNA...				J Med Chem 52: 2255-64 (2009) BindingDB Entry DOI: 10.7270/Q26112NJ
					More data for this Ligand-Target Pair
Transcription activator BRG1 [1448-1575] (Homo sapiens (Human))	BDBM394430 (1-(3-amino-6-(2- | US10308614, Example 31) Show SMILES CN(C)CC1(O)CCN(CC1)c1cc(nnc1N)-c1ccccc1O Show InChI InChI=1S/C18H25N5O2/c1-22(2)12-18(25)7-9-23(10-8-18)15-11-14(20-21-17(15)19)13-5-3-4-6-16(13)24/h3-6,11,24-25H,7-10,12H2,1-2H3,(H2,19,21)	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20.8	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research					Assay Description His-BRG1 (A1448-S1575; Swiss Prot P51532; mhhhhhhgslvpr\gsAEKLSPNPP NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNH KYRSLNDLEKDVMLLCQNA...				J Med Chem 52: 2255-64 (2009) BindingDB Entry DOI: 10.7270/Q26112NJ
					More data for this Ligand-Target Pair
Transcription activator BRG1 [1448-1575] (Homo sapiens (Human))	BDBM394622 (2-(6-amino-5-((1,4-trans)-4-methylcyclohexyl)pyrid...) Show SMILES C[C@H]1CC[C@H](CC1)c1cc(nnc1N)-c1ccccc1O |r,wU:4.7,1.0,(1.33,-5.78,;1.33,-4.23,;,-3.47,;,-1.93,;1.33,-1.15,;2.67,-1.93,;2.67,-3.47,;1.33,.38,;,1.15,;,2.69,;1.33,3.47,;2.67,2.69,;2.67,1.15,;4,.38,;-1.33,3.47,;-2.67,2.69,;-4,3.47,;-4,5,;-2.67,5.78,;-1.33,5,;,5.78,)| Show InChI InChI=1S/C17H21N3O/c1-11-6-8-12(9-7-11)14-10-15(19-20-17(14)18)13-4-2-3-5-16(13)21/h2-5,10-12,21H,6-9H2,1H3,(H2,18,20)/t11-,12+	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20.9	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research					Assay Description His-BRG1 (A1448-S1575; Swiss Prot P51532; mhhhhhhgslvpr\gsAEKLSPNPP NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNH KYRSLNDLEKDVMLLCQNA...				J Med Chem 52: 2255-64 (2009) BindingDB Entry DOI: 10.7270/Q26112NJ
					More data for this Ligand-Target Pair
Transcription activator BRG1 [1448-1575] (Homo sapiens (Human))	BDBM394414 (2-(6-amino-5-(4-(1- | US10308614, Example 15) Show SMILES CC(N1CCN(CC1)c1cc(nnc1N)-c1ccccc1O)c1ccccc1 Show InChI InChI=1S/C22H25N5O/c1-16(17-7-3-2-4-8-17)26-11-13-27(14-12-26)20-15-19(24-25-22(20)23)18-9-5-6-10-21(18)28/h2-10,15-16,28H,11-14H2,1H3,(H2,23,25)	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20.9	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research					Assay Description His-BRG1 (A1448-S1575; Swiss Prot P51532; mhhhhhhgslvpr\gsAEKLSPNPP NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNH KYRSLNDLEKDVMLLCQNA...				J Med Chem 52: 2255-64 (2009) BindingDB Entry DOI: 10.7270/Q26112NJ
					More data for this Ligand-Target Pair
Transcription activator BRG1 [1448-1575] (Homo sapiens (Human))	BDBM394399 (US10308614, Example 1 | tert-butyl 4-(3-amino-6-(2...) Show SMILES CC(C)(C)OC(=O)N1CCN(CC1)c1cc(nnc1N)-c1ccccc1O Show InChI InChI=1S/C19H25N5O3/c1-19(2,3)27-18(26)24-10-8-23(9-11-24)15-12-14(21-22-17(15)20)13-6-4-5-7-16(13)25/h4-7,12,25H,8-11H2,1-3H3,(H2,20,22)	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	US Patent	n/a	n/a	21.4	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research					Assay Description His-BRG1 (A1448-S1575; Swiss Prot P51532; mhhhhhhgslvpr\gsAEKLSPNPP NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNH KYRSLNDLEKDVMLLCQNA...				J Med Chem 52: 2255-64 (2009) BindingDB Entry DOI: 10.7270/Q26112NJ
					More data for this Ligand-Target Pair

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