Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
cGMP-dependent 3',5'-cyclic phosphodiesterase (Bos taurus) | BDBM50059037 ((6aR,9aS)-2-(Phenylmethyl)-5,6a,7,8,9,9a-hexahydro...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Inhibition of recombinant bovine adrenal cortex Phosphodiesterase 2 (PDE2) | J Med Chem 40: 2196-210 (1997) Article DOI: 10.1021/jm9608467 BindingDB Entry DOI: 10.7270/Q2G44PFZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-dependent 3',5'-cyclic phosphodiesterase (Bos taurus) | BDBM50059037 ((6aR,9aS)-2-(Phenylmethyl)-5,6a,7,8,9,9a-hexahydro...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Inhibition of Phosphodiesterase 2 from bovine aorta | J Med Chem 40: 4372-7 (1998) Article DOI: 10.1021/jm970495b BindingDB Entry DOI: 10.7270/Q2833R45 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-dependent 3',5'-cyclic phosphodiesterase (Bos taurus) | BDBM50059026 (5'-Methyl-2'-(biphenylmethyl)-3'-(phenylmethyl)spi...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Inhibition of recombinant bovine adrenal cortex Phosphodiesterase 2 (PDE2) | J Med Chem 40: 2196-210 (1997) Article DOI: 10.1021/jm9608467 BindingDB Entry DOI: 10.7270/Q2G44PFZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-dependent 3',5'-cyclic phosphodiesterase (Bos taurus) | BDBM50059044 ((6aR,9aS)-2-(Biphenylmethyl)-5,6a,7,8,9,9a-hexahyd...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Inhibition of recombinant bovine adrenal cortex Phosphodiesterase 2 (PDE2) | J Med Chem 40: 2196-210 (1997) Article DOI: 10.1021/jm9608467 BindingDB Entry DOI: 10.7270/Q2G44PFZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-dependent 3',5'-cyclic phosphodiesterase (Bos taurus) | BDBM50100673 (CHEMBL538498 | methyl 2-(4-aminophenyl)-4-(4-bromo...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tanabe Seiyaku Co., Ltd. Curated by ChEMBL | Assay Description Inhibition of bovine adrenal gland Phosphodiesterase 2 (PDE2) | J Med Chem 44: 2204-18 (2001) BindingDB Entry DOI: 10.7270/Q2QR4XT5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-dependent 3',5'-cyclic phosphodiesterase (Bos taurus) | BDBM50059061 ((6aR,9aS)-5,6a,7,8,9,9a-Hexahydro-5-methyl-2-(phen...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Inhibition of recombinant bovine adrenal cortex Phosphodiesterase 2 (PDE2) | J Med Chem 40: 2196-210 (1997) Article DOI: 10.1021/jm9608467 BindingDB Entry DOI: 10.7270/Q2G44PFZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-dependent 3',5'-cyclic phosphodiesterase (Bos taurus) | BDBM50100674 (CHEMBL541818 | methyl 2-(4-aminophenyl)-4-(3,5-dim...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 3.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tanabe Seiyaku Co., Ltd. Curated by ChEMBL | Assay Description Inhibition of bovine adrenal gland Phosphodiesterase 2 (PDE2) | J Med Chem 44: 2204-18 (2001) BindingDB Entry DOI: 10.7270/Q2QR4XT5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-dependent 3',5'-cyclic phosphodiesterase (Bos taurus) | BDBM50040375 (1,3-Bis(cyclopropylmethyl)-8-bis[(4-nitrophenylsul...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 5.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of phosphodiesterase 2 at 100 uM | J Med Chem 37: 476-85 (1994) BindingDB Entry DOI: 10.7270/Q2P26X6N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-dependent 3',5'-cyclic phosphodiesterase (Bos taurus) | BDBM50100662 (CHEMBL553371 | CHEMBL77971 | methyl 2-(4-aminophen...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 9.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tanabe Seiyaku Co., Ltd. Curated by ChEMBL | Assay Description Inhibitory activity against phosphodiesterase-2 (PDE2) isolated from bovine adrenal gland | Bioorg Med Chem Lett 13: 2341-5 (2003) BindingDB Entry DOI: 10.7270/Q2WQ04B2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-dependent 3',5'-cyclic phosphodiesterase (Bos taurus) | BDBM14390 (5-[2-ethoxy-5-(4-methyl-1-piperazinylsulfonyl)phen...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Tanabe Seiyaku Co., Ltd. Curated by ChEMBL | Assay Description Inhibition of bovine adrenal gland Phosphodiesterase 2 (PDE2) | J Med Chem 44: 2204-18 (2001) BindingDB Entry DOI: 10.7270/Q2QR4XT5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-dependent 3',5'-cyclic phosphodiesterase (Bos taurus) | BDBM50100659 (CHEMBL544289 | methyl 2-(4-aminophenyl)-1-oxo-7-(3...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Tanabe Seiyaku Co., Ltd. Curated by ChEMBL | Assay Description Inhibition of bovine adrenal gland Phosphodiesterase 2 (PDE2) | J Med Chem 44: 2204-18 (2001) BindingDB Entry DOI: 10.7270/Q2QR4XT5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-dependent 3',5'-cyclic phosphodiesterase (Bos taurus) | BDBM50100656 (2-(4-Amino-phenyl)-7-benzyloxy-1-oxo-4-(3,4,5-trim...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Tanabe Seiyaku Co., Ltd. Curated by ChEMBL | Assay Description Inhibition of bovine adrenal gland Phosphodiesterase 2 (PDE2) | J Med Chem 44: 2204-18 (2001) BindingDB Entry DOI: 10.7270/Q2QR4XT5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-dependent 3',5'-cyclic phosphodiesterase (Bos taurus) | BDBM50100670 (CHEMBL553786 | methyl 2-(4-aminophenyl)-1-oxo-7-(4...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Tanabe Seiyaku Co., Ltd. Curated by ChEMBL | Assay Description Inhibition of bovine adrenal gland Phosphodiesterase 2 (PDE2) | J Med Chem 44: 2204-18 (2001) BindingDB Entry DOI: 10.7270/Q2QR4XT5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-dependent 3',5'-cyclic phosphodiesterase (Bos taurus) | BDBM50100662 (CHEMBL553371 | CHEMBL77971 | methyl 2-(4-aminophen...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Tanabe Seiyaku Co., Ltd. Curated by ChEMBL | Assay Description Inhibition of bovine adrenal gland Phosphodiesterase 2 (PDE2) | J Med Chem 44: 2204-18 (2001) BindingDB Entry DOI: 10.7270/Q2QR4XT5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-dependent 3',5'-cyclic phosphodiesterase (Bos taurus) | BDBM50059063 (1-{4-[(Benzo[1,3]dioxol-5-ylmethyl)-amino]-6-chlor...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.09E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Inhibition of recombinant bovine adrenal cortex Phosphodiesterase 2 (PDE2) | J Med Chem 40: 2196-210 (1997) Article DOI: 10.1021/jm9608467 BindingDB Entry DOI: 10.7270/Q2G44PFZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-dependent 3',5'-cyclic phosphodiesterase (Bos taurus) | BDBM50061899 (2',5'-Dimethyl-3'-(phenylmethyl)spiro[cyclopentane...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Inhibition of Phosphodiesterase 2 from bovine adrenal cortex | J Med Chem 40: 4372-7 (1998) Article DOI: 10.1021/jm970495b BindingDB Entry DOI: 10.7270/Q2833R45 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-dependent 3',5'-cyclic phosphodiesterase (Bos taurus) | BDBM50059062 ((6aR,9aS)-2-Hexyl-5,6a,7,8,9,9a-hexahydro-5-methyl...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Inhibition of recombinant bovine adrenal cortex Phosphodiesterase 2 (PDE2) | J Med Chem 40: 2196-210 (1997) Article DOI: 10.1021/jm9608467 BindingDB Entry DOI: 10.7270/Q2G44PFZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-dependent 3',5'-cyclic phosphodiesterase (Bos taurus) | BDBM50059052 (5'-Methyl-2'-(cyclopentylmethyl)spiro[cyclopentane...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Inhibition of recombinant bovine adrenal cortex Phosphodiesterase 2 (PDE2) | J Med Chem 40: 2196-210 (1997) Article DOI: 10.1021/jm9608467 BindingDB Entry DOI: 10.7270/Q2G44PFZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-dependent 3',5'-cyclic phosphodiesterase (Bos taurus) | BDBM50059028 ((6aR,9aS)-5,6a,7,8,9,9a-Hexahydro-2,5-dimethyl-cyc...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Inhibition of recombinant bovine adrenal cortex Phosphodiesterase 2 (PDE2) | J Med Chem 40: 2196-210 (1997) Article DOI: 10.1021/jm9608467 BindingDB Entry DOI: 10.7270/Q2G44PFZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-dependent 3',5'-cyclic phosphodiesterase (Bos taurus) | BDBM50059054 (5'-Methyl-2'-phenyl-3'-(phenylmethyl)spiro[cyclope...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Inhibition of recombinant bovine adrenal cortex Phosphodiesterase 2 (PDE2) | J Med Chem 40: 2196-210 (1997) Article DOI: 10.1021/jm9608467 BindingDB Entry DOI: 10.7270/Q2G44PFZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-dependent 3',5'-cyclic phosphodiesterase (Bos taurus) | BDBM50059024 ((6aR,9aS)-2-(Cyclopentylmethyl)-5,6a,7,8,9,9a-hexa...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute Curated by ChEMBL | Assay Description Inhibition of recombinant bovine adrenal cortex Phosphodiesterase 2 (PDE2) | J Med Chem 40: 2196-210 (1997) Article DOI: 10.1021/jm9608467 BindingDB Entry DOI: 10.7270/Q2G44PFZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-dependent 3',5'-cyclic phosphodiesterase (Bos taurus) | BDBM50130021 (7-(2-Methyl-pyridin-4-ylmethyl)-8-oxo-2-(pyridin-2...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Tanabe Seiyaku Co., Ltd. Curated by ChEMBL | Assay Description Inhibitory activity against phosphodiesterase-2 (PDE2) isolated from bovine adrenal gland | Bioorg Med Chem Lett 13: 2341-5 (2003) BindingDB Entry DOI: 10.7270/Q2WQ04B2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-dependent 3',5'-cyclic phosphodiesterase (Bos taurus) | BDBM14390 (5-[2-ethoxy-5-(4-methyl-1-piperazinylsulfonyl)phen...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | 4.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Tanabe Seiyaku Co., Ltd. Curated by ChEMBL | Assay Description Inhibitory activity against phosphodiesterase-2 (PDE2) isolated from bovine adrenal gland | Bioorg Med Chem Lett 13: 2341-5 (2003) BindingDB Entry DOI: 10.7270/Q2WQ04B2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-dependent 3',5'-cyclic phosphodiesterase (Bos taurus) | BDBM50242771 (8-Benzyl-2-methyl-4-(N-methylamino)pyrazolo[1,5-a]...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Université Louis Pasteur Curated by ChEMBL | Assay Description Inhibition of bovine aorta PDE2 in presence of cGMP | Eur J Med Chem 43: 816-29 (2008) Article DOI: 10.1016/j.ejmech.2007.05.016 BindingDB Entry DOI: 10.7270/Q2F76C9X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-dependent 3',5'-cyclic phosphodiesterase (Bos taurus) | BDBM50130016 (8-(2-Hydroxy-ethylamino)-2-(2-methyl-pyridin-4-ylm...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 7.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Tanabe Seiyaku Co., Ltd. Curated by ChEMBL | Assay Description Inhibitory activity against phosphodiesterase-2 (PDE2) isolated from bovine adrenal gland | Bioorg Med Chem Lett 13: 2341-5 (2003) BindingDB Entry DOI: 10.7270/Q2WQ04B2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-dependent 3',5'-cyclic phosphodiesterase (Bos taurus) | BDBM50130026 (7-(2-Methyl-pyridin-4-ylmethyl)-8-oxo-2-(pyrimidin...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Tanabe Seiyaku Co., Ltd. Curated by ChEMBL | Assay Description Inhibitory activity against phosphodiesterase-2 (PDE2) isolated from bovine adrenal gland | Bioorg Med Chem Lett 13: 2341-5 (2003) BindingDB Entry DOI: 10.7270/Q2WQ04B2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-dependent 3',5'-cyclic phosphodiesterase (Bos taurus) | BDBM50130024 (2-(2-Methyl-pyridin-4-ylmethyl)-1-oxo-8-(2-pyridin...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Tanabe Seiyaku Co., Ltd. Curated by ChEMBL | Assay Description Inhibitory activity against phosphodiesterase-2 (PDE2) isolated from bovine adrenal gland | Bioorg Med Chem Lett 13: 2341-5 (2003) BindingDB Entry DOI: 10.7270/Q2WQ04B2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-dependent 3',5'-cyclic phosphodiesterase (Bos taurus) | BDBM50130017 (2-(2-Methyl-pyridin-4-ylmethyl)-1-oxo-8-(pyrimidin...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Tanabe Seiyaku Co., Ltd. Curated by ChEMBL | Assay Description Inhibitory activity against phosphodiesterase-2 (PDE2) isolated from bovine adrenal gland | Bioorg Med Chem Lett 13: 2341-5 (2003) BindingDB Entry DOI: 10.7270/Q2WQ04B2 | |||||||||||
More data for this Ligand-Target Pair |