Compile Data Set for Download or QSAR

Found 451 hits Enz. Inhib. hit(s) with all data for entry = 2311   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Estrogen receptor (Homo sapiens (Human))	BDBM361453 (2,2-difluoro-3- ((1R,3R)-1-(6- fluoro-3-(2- ((3- f...) Show SMILES C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC(F)(F)CO)c1c(F)ccc(OCCNCCCF)c1C |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB US Patent	n/a	n/a	0.0340	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...				US Patent US10221173 (2019) BindingDB Entry DOI: 10.7270/Q2HD7XZS
					More data for this Ligand-Target Pair				3D Structure (crystal)
Estrogen receptor (Homo sapiens (Human))	BDBM361490 (N-(2-(3- ((1R,3R)-2- (2,2- difluoroethyl)- 3-methy...) Show SMILES COc1ccc(OCCNCCCF)c(F)c1[C@H]1N(CC(F)F)[C@H](C)Cc2c1[nH]c1ccccc21 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0420	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...				US Patent US10221173 (2019) BindingDB Entry DOI: 10.7270/Q2HD7XZS
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM361518 (2,2-difluoro-3- ((1R,3R)-1-(5- fluoro-2-(2- ((3- f...) Show SMILES C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC(F)(F)CO)c1c(F)cnc(OCCNCCCF)c1C |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0450	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...				US Patent US10221173 (2019) BindingDB Entry DOI: 10.7270/Q2HD7XZS
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM361473 (3-((1R,3R)-1- (3,5-difluoro- 2-(2-((3- fluoropropy...) Show SMILES C[C@@H]1Cc2c([nH]c3ccc(F)cc23)[C@H](N1CC(F)(F)CO)c1c(F)cnc(OCCNCCCF)c1F |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0580	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...				US Patent US10221173 (2019) BindingDB Entry DOI: 10.7270/Q2HD7XZS
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM361420 (Preparation of 3-fluoro-N-(2-((5-methoxy-4-((1R,3R...) Show SMILES COc1cnc(OCCNCCCF)cc1[C@H]1N(CC(F)(F)F)[C@H](C)Cc2c1[nH]c1ccccc21 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0590	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...				US Patent US10221173 (2019) BindingDB Entry DOI: 10.7270/Q2HD7XZS
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM361495 (3-((1R,3R)-1- (6-fluoro-3-(2- ((3- fluoropropyl) a...) Show SMILES C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CCC#N)c1c(F)ccc(OCCNCCCF)c1C |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0650	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...				US Patent US10221173 (2019) BindingDB Entry DOI: 10.7270/Q2HD7XZS
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM361519 (3-((1R,3R)-1- (3-chloro-5- fluoro-2-(2- ((3- fluor...) Show SMILES C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC(F)(F)CO)c1c(F)cnc(OCCNCCCF)c1Cl |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0700	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...				US Patent US10221173 (2019) BindingDB Entry DOI: 10.7270/Q2HD7XZS
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM361472 (3-((1R,3R)-1- (3,5-difluoro- 2-(2-((3- fluoropropy...) Show SMILES C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC(F)(F)CO)c1c(F)cnc(OCCNCCCF)c1F |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0710	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...				US Patent US10221173 (2019) BindingDB Entry DOI: 10.7270/Q2HD7XZS
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM361470 (3-((1R,3R)-1- (2,6-difluoro- 3-(2-((3- fluoropropy...) Show SMILES C[C@@H]1Cc2c([nH]c3cccc(F)c23)[C@H](N1CC(F)(F)CO)c1c(F)ccc(OCCNCCCF)c1F |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0760	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...				US Patent US10221173 (2019) BindingDB Entry DOI: 10.7270/Q2HD7XZS
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM361423 (3-((1R,3R)-1-(2,6-difluoro-3-(2-((3-fluoropropyl)a...) Show SMILES C[C@@H]1Cc2c([nH]c3ccc(F)cc23)[C@H](N1CC(F)(F)CO)c1c(F)ccc(OCCNCCCF)c1F |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0790	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...				US Patent US10221173 (2019) BindingDB Entry DOI: 10.7270/Q2HD7XZS
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM361441 (3-fluoro-N-(2- (4-fluoro-2- methyl-3- ((1R,3R)-3- ...) Show SMILES C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC(F)(F)F)c1c(F)ccc(OCCNCCCF)c1C |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0810	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...				US Patent US10221173 (2019) BindingDB Entry DOI: 10.7270/Q2HD7XZS
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM361511 (2,2-difluoro-3- ((1R,3R)-1-(2- (2-((3- fluoropropy...) Show SMILES C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC(F)(F)CO)c1ccnc(OCCNCCCF)c1C |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0840	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...				US Patent US10221173 (2019) BindingDB Entry DOI: 10.7270/Q2HD7XZS
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM361417 (Preparation of N-(2-(2,4-difluoro-3-((1R,3R)-3-met...) Show SMILES C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC(F)(F)F)c1c(F)ccc(OCCNCCCF)c1F |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0880	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...				US Patent US10221173 (2019) BindingDB Entry DOI: 10.7270/Q2HD7XZS
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM361493 (3-((1R,3R)-1- (2-chloro-6- fluoro-3-(2- ((3- fluor...) Show SMILES C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC(F)(F)CO)c1c(F)ccc(OCCNCCCF)c1Cl |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0890	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...				US Patent US10221173 (2019) BindingDB Entry DOI: 10.7270/Q2HD7XZS
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM361422 (3-((1R,3R)-1-(2,6-difluoro-3-(2-((3-fluoropropyl)a...) Show SMILES C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC(F)(F)CO)c1c(F)ccc(OCCNCCCF)c1F |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0920	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...				US Patent US10221173 (2019) BindingDB Entry DOI: 10.7270/Q2HD7XZS
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM361476 (3-((1R,3R)-1- (2- (difluoromethyl)- 3-(2-((3- fluo...) Show SMILES C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC(F)(F)CO)c1cccc(OCCNCCCF)c1C(F)F |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0950	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...				US Patent US10221173 (2019) BindingDB Entry DOI: 10.7270/Q2HD7XZS
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM361514 (3-fluoro-N-(2- ((3-methyl-4- ((1R,3R)-3- methyl-2-...) Show SMILES C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC(F)(F)F)c1ccnc(OCCNCCCF)c1C |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0950	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...				US Patent US10221173 (2019) BindingDB Entry DOI: 10.7270/Q2HD7XZS
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM361475 (3-((1R,3R)-1- (3,5-difluoro- 2-(2-((3- fluoropropy...) Show SMILES C[C@@H]1Cc2c([nH]c3ccc(F)cc23)[C@H](N1CC(F)(F)CO)c1c(F)cnc(OCCN(C)CCCF)c1F |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.0990	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...				US Patent US10221173 (2019) BindingDB Entry DOI: 10.7270/Q2HD7XZS
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM361486 (N-(2-(4- chloro-2- fluoro-3- ((1R,3R)-3- methyl-2-...) Show SMILES C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC(F)(F)F)c1c(Cl)ccc(OCCNCCCF)c1F |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.120	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...				US Patent US10221173 (2019) BindingDB Entry DOI: 10.7270/Q2HD7XZS
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM361430 (N-(2-(4- chloro-3- ((1R,3R)-3- methyl-2- (2,2,2- t...) Show SMILES C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC(F)(F)F)c1cc(OCCNCCCF)ccc1Cl |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.120	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...				US Patent US10221173 (2019) BindingDB Entry DOI: 10.7270/Q2HD7XZS
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM361415 (3-Fluoro-N-(2-(4-methoxy-3-((1R,3R)-3-methyl-2-(2,...) Show SMILES COc1ccc(OCCNCCCF)cc1[C@H]1N(CC(F)(F)F)[C@H](C)Cc2c1[nH]c1ccccc21 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.120	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...				US Patent US10221173 (2019) BindingDB Entry DOI: 10.7270/Q2HD7XZS
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM361468 (3-((1R,3R)-1- (2,6-difluoro- 3-(2-((3- fluoropropy...) Show SMILES C[C@@H]1Cc2c([nH]c3c(F)cccc23)[C@H](N1CC(F)(F)CO)c1c(F)ccc(OCCNCCCF)c1F |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.120	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...				US Patent US10221173 (2019) BindingDB Entry DOI: 10.7270/Q2HD7XZS
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM361459 (N-(2-(3- ((1R,3R)-2- (2,2- difluoroethyl)- 3-methy...) Show SMILES C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC(F)F)c1c(F)ccc(OCCNCCCF)c1F |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.120	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...				US Patent US10221173 (2019) BindingDB Entry DOI: 10.7270/Q2HD7XZS
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM361419 (Preparation of 3-fluoro-N-(2-(2-fluoro-4-methoxy-3...) Show SMILES COc1ccc(OCCNCCCF)c(F)c1[C@H]1N(CC(F)(F)F)[C@H](C)Cc2c1[nH]c1ccccc21 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.140	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...				US Patent US10221173 (2019) BindingDB Entry DOI: 10.7270/Q2HD7XZS
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM361452 (3-((1R,3R)-1- (2-chloro-5-(2- ((3- fluoropropyl) a...) Show SMILES C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC(F)(F)CO)c1cc(OCCNCCCF)ccc1Cl |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.140	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...				US Patent US10221173 (2019) BindingDB Entry DOI: 10.7270/Q2HD7XZS
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM361497 (3-((1R,3R)-1- (2,6-difluoro- 3-((2-((3- fluoroprop...) Show SMILES C[C@@H]1Cc2c([nH]c3ccc(F)cc23)[C@H](N1CC(F)(F)CO)c1c(F)ccc(NCCNCCCF)c1F |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.140	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...				US Patent US10221173 (2019) BindingDB Entry DOI: 10.7270/Q2HD7XZS
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM361457 (2,2-difluoro-3- ((1R,3R)-1-(5- ((S)-2-((3- fluorop...) Show SMILES COc1ccc(OC[C@H](C)NCCCF)cc1[C@H]1N(CC(F)(F)CO)[C@H](C)Cc2c1[nH]c1ccccc21 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.150	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...				US Patent US10221173 (2019) BindingDB Entry DOI: 10.7270/Q2HD7XZS
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM361434 (3-fluoro-N-(2- (4-methoxy-2- methyl-3- ((1R,3R)-3-...) Show SMILES COc1ccc(OCCNCCCF)c(C)c1[C@H]1N(CC(F)(F)F)[C@H](C)Cc2c1[nH]c1ccccc21 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.160	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...				US Patent US10221173 (2019) BindingDB Entry DOI: 10.7270/Q2HD7XZS
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM361492 (3-fluoro-N-(2- (2-fluoro-3- ((1R,3R)-2-((3- fluoro...) Show SMILES COc1ccc(OCCNCCCF)c(F)c1[C@H]1N(CC2(F)COC2)[C@H](C)Cc2c1[nH]c1ccccc21 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.160	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...				US Patent US10221173 (2019) BindingDB Entry DOI: 10.7270/Q2HD7XZS
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM361487 (N-(2-(2,4- dimethyl-3- ((1R,3R)-3- methyl-2- (2,2,...) Show SMILES C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC(F)(F)F)c1c(C)ccc(OCCNCCCF)c1C |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.160	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...				US Patent US10221173 (2019) BindingDB Entry DOI: 10.7270/Q2HD7XZS
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM361494 (2,2-difluoro-3- ((1R,3R)-6- fluoro-1-(2- fluoro-3-...) Show SMILES COc1ccc(OCCNCCCF)c(F)c1[C@H]1N(CC(F)(F)CO)[C@H](C)Cc2c1[nH]c1ccc(F)cc21 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.170	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...				US Patent US10221173 (2019) BindingDB Entry DOI: 10.7270/Q2HD7XZS
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM361489 (2,2-difluoro-3- ((1R,3R)-1-(2- fluoro-3-(2- ((3- f...) Show SMILES COc1ccc(OCCNCCCF)c(F)c1[C@H]1N(CC(F)(F)CO)[C@H](C)Cc2c1[nH]c1ccccc21 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.170	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...				US Patent US10221173 (2019) BindingDB Entry DOI: 10.7270/Q2HD7XZS
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM361512 (3-((1R,3R)-1- (3-chloro-2-(2- ((3- fluoropropyl) a...) Show SMILES C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC(F)(F)CO)c1ccnc(OCCNCCCF)c1Cl |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.170	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...				US Patent US10221173 (2019) BindingDB Entry DOI: 10.7270/Q2HD7XZS
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM361566 (Preparation of 3-((1R,3R)-1-(5-fluoro-2-(2-((3-flu...) Show SMILES CC(CC(O)=O)N1[C@H](C)Cc2c([nH]c3ccccc23)[C@H]1c1c(F)cnc(OCCN(C)CCCF)c1C |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.180	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...				US Patent US10221173 (2019) BindingDB Entry DOI: 10.7270/Q2HD7XZS
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM361446 (3-fluoro-N-(2- ((4-methyl-5- ((1R,3R)-3- methyl-2-...) Show SMILES C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC(F)(F)F)c1cncc(OCCNCCCF)c1C |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.190	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...				US Patent US10221173 (2019) BindingDB Entry DOI: 10.7270/Q2HD7XZS
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM361414 (N-(2-(3-((1R,3R)-2-(2,2-difluoroethyl)-3-methyl-2,...) Show SMILES COc1ccc(OCCNCCCF)cc1[C@H]1N(CC(F)F)[C@H](C)Cc2c1[nH]c1ccccc21 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.190	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...				US Patent US10221173 (2019) BindingDB Entry DOI: 10.7270/Q2HD7XZS
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM361469 (3-((1R,3R)-1- (2,6-difluoro- 3-(2-((3- fluoropropy...) Show SMILES C[C@@H]1Cc2c([nH]c3cc(F)ccc23)[C@H](N1CC(F)(F)CO)c1c(F)ccc(OCCNCCCF)c1F |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.190	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...				US Patent US10221173 (2019) BindingDB Entry DOI: 10.7270/Q2HD7XZS
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM361416 (2,2-Difluoro-3-((1R,3R)-1-(5-(2-((3-fluoropropyl)a...) Show SMILES COc1ccc(OCCNCCCF)cc1[C@H]1N(CC(F)(F)CO)[C@H](C)Cc2c1[nH]c1ccccc21 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...				US Patent US10221173 (2019) BindingDB Entry DOI: 10.7270/Q2HD7XZS
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM361522 (3-fluoro-N-(2- ((5-methyl-6- ((1S,3R)-3- methyl-2-...) Show SMILES C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC(F)(F)F)c1ncnc(OCCNCCCF)c1C |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...				US Patent US10221173 (2019) BindingDB Entry DOI: 10.7270/Q2HD7XZS
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM361504 (2,2-difluoro-3- ((1S,3R)-1-(4- (2-((3- fluoropropy...) Show SMILES C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC(F)(F)CO)c1nccc(OCCNCCCF)c1C |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...				US Patent US10221173 (2019) BindingDB Entry DOI: 10.7270/Q2HD7XZS
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM361563 ((2R)-3-[(1R,3R)-6-fluoro-1-[5-fluoro-2-[2-[3-fluor...) Show SMILES C[C@H](CN1[C@H](C)Cc2c([nH]c3ccc(F)cc23)[C@H]1c1c(F)cnc(OCCN(C)CCCF)c1C)C(O)=O |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.210	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...				US Patent US10221173 (2019) BindingDB Entry DOI: 10.7270/Q2HD7XZS
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM361515 (N-(2-((3,5- difluoro-4- ((1R,3R)-3- methyl-2- (2,2...) Show SMILES C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC(F)(F)F)c1c(F)cnc(OCCNCCCF)c1F |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.210	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...				US Patent US10221173 (2019) BindingDB Entry DOI: 10.7270/Q2HD7XZS
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM361484 (N-(2-(2,4- difluoro-3- ((1R,3R)-2-((1- fluorocyclo...) Show SMILES C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC1(F)CC1)c1c(F)ccc(OCCNCCCF)c1F |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.210	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...				US Patent US10221173 (2019) BindingDB Entry DOI: 10.7270/Q2HD7XZS
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM361454 (2,2-difluoro-3- ((1R,3R)-6- fluoro-1-(5-(2- ((3- f...) Show SMILES COc1ccc(OCCNCCCF)cc1[C@H]1N(CC(F)(F)CO)[C@H](C)Cc2c1[nH]c1ccc(F)cc21 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.220	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...				US Patent US10221173 (2019) BindingDB Entry DOI: 10.7270/Q2HD7XZS
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM361421 (Preparation of N-(2-(2,4-difluoro-3-((1R,3R)-2-((3...) Show SMILES C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC1(F)COC1)c1c(F)ccc(OCCNCCCF)c1F |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.220	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...				US Patent US10221173 (2019) BindingDB Entry DOI: 10.7270/Q2HD7XZS
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM361418 (Preparation of 3-fluoro-N-(2-(4-fluoro-3-((1R,3R)-...) Show SMILES C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC(F)(F)F)c1cc(OCCNCCCF)ccc1F |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.230	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...				US Patent US10221173 (2019) BindingDB Entry DOI: 10.7270/Q2HD7XZS
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM361433 (N-(2-(2- chloro-3- ((1R,3R)-3- methyl-2- (2,2,2- t...) Show SMILES C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC(F)(F)F)c1cccc(OCCNCCCF)c1Cl |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.25	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...				US Patent US10221173 (2019) BindingDB Entry DOI: 10.7270/Q2HD7XZS
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM361447 (3-fluoroN-(2- ((5-fluoro-4- ((1R,3R)-3- methyl-2- ...) Show SMILES C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC(F)(F)F)c1cc(OCCNCCCF)ncc1F |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.260	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...				US Patent US10221173 (2019) BindingDB Entry DOI: 10.7270/Q2HD7XZS
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM361491 (3-fluoro-N-(2- (2-fluoro-3- ((1R,3R)-2-((1- fluoro...) Show SMILES COc1ccc(OCCNCCCF)c(F)c1[C@H]1N(CC2(F)CC2)[C@H](C)Cc2c1[nH]c1ccccc21 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.280	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...				US Patent US10221173 (2019) BindingDB Entry DOI: 10.7270/Q2HD7XZS
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM361496 (N1-(2,4- difluoro-3- ((1R,3R)-3- methyl-2- (2,2,2-...) Show SMILES C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](N1CC(F)(F)F)c1c(F)ccc(NCCNCCCF)c1F |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.280	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...				US Patent US10221173 (2019) BindingDB Entry DOI: 10.7270/Q2HD7XZS
					More data for this Ligand-Target Pair

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