Compile Data Set for Download or QSAR

Found 69 hits Enz. Inhib. hit(s) with all data for entry = 50031546   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50315107 (4-(3-(4-chlorophenyl)-4-(pyridin-4-yl)-1H-pyrazol-...) Show SMILES NS(=O)(=O)N1CCC(CC1)c1[nH]nc(c1-c1ccncc1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C19H20ClN5O2S/c20-16-3-1-14(2-4-16)18-17(13-5-9-22-10-6-13)19(24-23-18)15-7-11-25(12-8-15)28(21,26)27/h1-6,9-10,15H,7-8,11-12H2,(H,23,24)(H2,21,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of p38alpha assessed as gamma-[33P]ATP incorporation by scintillation counting				Bioorg Med Chem Lett 20: 2634-8 (2010) Article DOI: 10.1016/j.bmcl.2010.02.047 BindingDB Entry DOI: 10.7270/Q21N818H
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50315120 ((1S,2S)-2-(4-(3-(4-chlorophenyl)-4-(pyrimidin-4-yl...) Show SMILES O[C@H]1CCC[C@@H]1N1CCC(CC1)c1[nH]nc(c1-c1ccncn1)-c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C23H26ClN5O/c24-17-6-4-15(5-7-17)22-21(18-8-11-25-14-26-18)23(28-27-22)16-9-12-29(13-10-16)19-2-1-3-20(19)30/h4-8,11,14,16,19-20,30H,1-3,9-10,12-13H2,(H,27,28)/t19-,20-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of p38alpha assessed as gamma-[33P]ATP incorporation by scintillation counting				Bioorg Med Chem Lett 20: 2634-8 (2010) Article DOI: 10.1016/j.bmcl.2010.02.047 BindingDB Entry DOI: 10.7270/Q21N818H
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50315129 (4-(3-(4-fluorophenyl)-5-(piperidin-4-yl)-1H-pyrazo...) Show SMILES Fc1ccc(cc1)-c1n[nH]c(C2CCNCC2)c1-c1ccncc1 Show InChI InChI=1S/C19H19FN4/c20-16-3-1-14(2-4-16)18-17(13-5-9-21-10-6-13)19(24-23-18)15-7-11-22-12-8-15/h1-6,9-10,15,22H,7-8,11-12H2,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	25.3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of p38alpha assessed as gamma-[33P]ATP incorporation by scintillation counting				Bioorg Med Chem Lett 20: 2634-8 (2010) Article DOI: 10.1016/j.bmcl.2010.02.047 BindingDB Entry DOI: 10.7270/Q21N818H
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50315134 (4-(5-(1-methylpiperidin-4-yl)-3-(3-(trifluoromethy...) Show SMILES CN1CCC(CC1)c1[nH]nc(c1-c1ccncc1)-c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C21H21F3N4/c1-28-11-7-15(8-12-28)19-18(14-5-9-25-10-6-14)20(27-26-19)16-3-2-4-17(13-16)21(22,23)24/h2-6,9-10,13,15H,7-8,11-12H2,1H3,(H,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	26.5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of p38alpha assessed as gamma-[33P]ATP incorporation by scintillation counting				Bioorg Med Chem Lett 20: 2634-8 (2010) Article DOI: 10.1016/j.bmcl.2010.02.047 BindingDB Entry DOI: 10.7270/Q21N818H
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50315118 (4-(3-(4-chlorophenyl)-5-(1-(tetrahydrofuran-3-yl)p...) Show SMILES Clc1ccc(cc1)-c1n[nH]c(C2CCN(CC2)C2CCOC2)c1-c1ccncn1 Show InChI InChI=1S/C22H24ClN5O/c23-17-3-1-15(2-4-17)21-20(19-5-9-24-14-25-19)22(27-26-21)16-6-10-28(11-7-16)18-8-12-29-13-18/h1-5,9,14,16,18H,6-8,10-13H2,(H,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of p38alpha assessed as gamma-[33P]ATP incorporation by scintillation counting				Bioorg Med Chem Lett 20: 2634-8 (2010) Article DOI: 10.1016/j.bmcl.2010.02.047 BindingDB Entry DOI: 10.7270/Q21N818H
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50315131 (4-(3-(4-chlorophenyl)-5-(1-methylpiperidin-4-yl)-1...) Show SMILES CN1CCC(CC1)c1[nH]nc(c1-c1ccncc1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C20H21ClN4/c1-25-12-8-16(9-13-25)20-18(14-6-10-22-11-7-14)19(23-24-20)15-2-4-17(21)5-3-15/h2-7,10-11,16H,8-9,12-13H2,1H3,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	31.6	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of p38alpha assessed as gamma-[33P]ATP incorporation by scintillation counting				Bioorg Med Chem Lett 20: 2634-8 (2010) Article DOI: 10.1016/j.bmcl.2010.02.047 BindingDB Entry DOI: 10.7270/Q21N818H
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50315115 (2-(4-(3-(4-chlorophenyl)-4-(pyrimidin-4-yl)-1H-pyr...) Show SMILES OCCN1CCC(CC1)c1[nH]nc(c1-c1ccncn1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C20H22ClN5O/c21-16-3-1-14(2-4-16)19-18(17-5-8-22-13-23-17)20(25-24-19)15-6-9-26(10-7-15)11-12-27/h1-5,8,13,15,27H,6-7,9-12H2,(H,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of p38alpha assessed as gamma-[33P]ATP incorporation by scintillation counting				Bioorg Med Chem Lett 20: 2634-8 (2010) Article DOI: 10.1016/j.bmcl.2010.02.047 BindingDB Entry DOI: 10.7270/Q21N818H
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50315132 (4-(3-(3-chlorophenyl)-5-(1-methylpiperidin-4-yl)-1...) Show SMILES CN1CCC(CC1)c1[nH]nc(c1-c1ccncc1)-c1cccc(Cl)c1 Show InChI InChI=1S/C20H21ClN4/c1-25-11-7-15(8-12-25)19-18(14-5-9-22-10-6-14)20(24-23-19)16-3-2-4-17(21)13-16/h2-6,9-10,13,15H,7-8,11-12H2,1H3,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	39.2	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of p38alpha assessed as gamma-[33P]ATP incorporation by scintillation counting				Bioorg Med Chem Lett 20: 2634-8 (2010) Article DOI: 10.1016/j.bmcl.2010.02.047 BindingDB Entry DOI: 10.7270/Q21N818H
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50315133 (4-(5-(1-methylpiperidin-4-yl)-3-(4-(trifluoromethy...) Show SMILES CN1CCC(CC1)c1[nH]nc(c1-c1ccncc1)-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C21H21F3N4/c1-28-12-8-16(9-13-28)20-18(14-6-10-25-11-7-14)19(26-27-20)15-2-4-17(5-3-15)21(22,23)24/h2-7,10-11,16H,8-9,12-13H2,1H3,(H,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	40.5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of p38alpha assessed as gamma-[33P]ATP incorporation by scintillation counting				Bioorg Med Chem Lett 20: 2634-8 (2010) Article DOI: 10.1016/j.bmcl.2010.02.047 BindingDB Entry DOI: 10.7270/Q21N818H
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50315104 (2-(4-(3-(4-chlorophenyl)-4-(pyridin-4-yl)-1H-pyraz...) Show SMILES OCCN1CCC(CC1)c1[nH]nc(c1-c1ccncc1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C21H23ClN4O/c22-18-3-1-16(2-4-18)20-19(15-5-9-23-10-6-15)21(25-24-20)17-7-11-26(12-8-17)13-14-27/h1-6,9-10,17,27H,7-8,11-14H2,(H,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of p38alpha assessed as gamma-[33P]ATP incorporation by scintillation counting				Bioorg Med Chem Lett 20: 2634-8 (2010) Article DOI: 10.1016/j.bmcl.2010.02.047 BindingDB Entry DOI: 10.7270/Q21N818H
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50315121 (4-(3-(4-chlorophenyl)-5-(1-(pyridin-4-ylmethyl)pip...) Show SMILES Clc1ccc(cc1)-c1n[nH]c(C2CCN(Cc3ccncc3)CC2)c1-c1ccncn1 Show InChI InChI=1S/C24H23ClN6/c25-20-3-1-18(2-4-20)23-22(21-7-12-27-16-28-21)24(30-29-23)19-8-13-31(14-9-19)15-17-5-10-26-11-6-17/h1-7,10-12,16,19H,8-9,13-15H2,(H,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of p38alpha assessed as gamma-[33P]ATP incorporation by scintillation counting				Bioorg Med Chem Lett 20: 2634-8 (2010) Article DOI: 10.1016/j.bmcl.2010.02.047 BindingDB Entry DOI: 10.7270/Q21N818H
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50315114 (4-(3-(4-chlorophenyl)-5-(1-methylpiperidin-4-yl)-1...) Show SMILES CN1CCC(CC1)c1[nH]nc(c1-c1ccncn1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C19H20ClN5/c1-25-10-7-14(8-11-25)19-17(16-6-9-21-12-22-16)18(23-24-19)13-2-4-15(20)5-3-13/h2-6,9,12,14H,7-8,10-11H2,1H3,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of p38alpha assessed as gamma-[33P]ATP incorporation by scintillation counting				Bioorg Med Chem Lett 20: 2634-8 (2010) Article DOI: 10.1016/j.bmcl.2010.02.047 BindingDB Entry DOI: 10.7270/Q21N818H
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50315127 (4-(3-(4-fluorophenyl)-5-(piperidin-3-yl)-1H-pyrazo...) Show SMILES Fc1ccc(cc1)-c1n[nH]c(C2CCCNC2)c1-c1ccncc1 Show InChI InChI=1S/C19H19FN4/c20-16-5-3-14(4-6-16)18-17(13-7-10-21-11-8-13)19(24-23-18)15-2-1-9-22-12-15/h3-8,10-11,15,22H,1-2,9,12H2,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	48.3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of p38alpha assessed as gamma-[33P]ATP incorporation by scintillation counting				Bioorg Med Chem Lett 20: 2634-8 (2010) Article DOI: 10.1016/j.bmcl.2010.02.047 BindingDB Entry DOI: 10.7270/Q21N818H
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50315130 (4-(3-(4-fluorophenyl)-5-(1-methylpiperidin-4-yl)-1...) Show SMILES CN1CCC(CC1)c1[nH]nc(c1-c1ccncc1)-c1ccc(F)cc1 Show InChI InChI=1S/C20H21FN4/c1-25-12-8-16(9-13-25)20-18(14-6-10-22-11-7-14)19(23-24-20)15-2-4-17(21)5-3-15/h2-7,10-11,16H,8-9,12-13H2,1H3,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	54.7	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of p38alpha assessed as gamma-[33P]ATP incorporation by scintillation counting				Bioorg Med Chem Lett 20: 2634-8 (2010) Article DOI: 10.1016/j.bmcl.2010.02.047 BindingDB Entry DOI: 10.7270/Q21N818H
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50315103 (4-(5-(1-methylpiperidin-4-yl)-3-m-tolyl-1H-pyrazol...) Show SMILES CN1CCC(CC1)c1[nH]nc(c1-c1ccncc1)-c1cccc(C)c1 Show InChI InChI=1S/C21H24N4/c1-15-4-3-5-18(14-15)21-19(16-6-10-22-11-7-16)20(23-24-21)17-8-12-25(2)13-9-17/h3-7,10-11,14,17H,8-9,12-13H2,1-2H3,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	67.3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of p38alpha assessed as gamma-[33P]ATP incorporation by scintillation counting				Bioorg Med Chem Lett 20: 2634-8 (2010) Article DOI: 10.1016/j.bmcl.2010.02.047 BindingDB Entry DOI: 10.7270/Q21N818H
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50315110 (1-(4-(3-(4-chlorophenyl)-4-(pyridin-4-yl)-1H-pyraz...) Show SMILES CC(=O)N1CCC(CC1)c1[nH]nc(c1-c1ccncc1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C21H21ClN4O/c1-14(27)26-12-8-17(9-13-26)21-19(15-6-10-23-11-7-15)20(24-25-21)16-2-4-18(22)5-3-16/h2-7,10-11,17H,8-9,12-13H2,1H3,(H,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	68	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of p38alpha assessed as gamma-[33P]ATP incorporation by scintillation counting				Bioorg Med Chem Lett 20: 2634-8 (2010) Article DOI: 10.1016/j.bmcl.2010.02.047 BindingDB Entry DOI: 10.7270/Q21N818H
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50315108 (4-(3-(4-chlorophenyl)-5-(1-(methylsulfonyl)piperid...) Show SMILES CS(=O)(=O)N1CCC(CC1)c1[nH]nc(c1-c1ccncc1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C20H21ClN4O2S/c1-28(26,27)25-12-8-16(9-13-25)20-18(14-6-10-22-11-7-14)19(23-24-20)15-2-4-17(21)5-3-15/h2-7,10-11,16H,8-9,12-13H2,1H3,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of p38alpha assessed as gamma-[33P]ATP incorporation by scintillation counting				Bioorg Med Chem Lett 20: 2634-8 (2010) Article DOI: 10.1016/j.bmcl.2010.02.047 BindingDB Entry DOI: 10.7270/Q21N818H
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50315105 (4-(3-(4-chlorophenyl)-5-(1-(2-methoxyethyl)piperid...) Show SMILES COCCN1CCC(CC1)c1[nH]nc(c1-c1ccncc1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C22H25ClN4O/c1-28-15-14-27-12-8-18(9-13-27)22-20(16-6-10-24-11-7-16)21(25-26-22)17-2-4-19(23)5-3-17/h2-7,10-11,18H,8-9,12-15H2,1H3,(H,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of p38alpha assessed as gamma-[33P]ATP incorporation by scintillation counting				Bioorg Med Chem Lett 20: 2634-8 (2010) Article DOI: 10.1016/j.bmcl.2010.02.047 BindingDB Entry DOI: 10.7270/Q21N818H
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50315112 (1-(4-(3-(4-chlorophenyl)-4-(pyridin-4-yl)-1H-pyraz...) Show SMILES COCC(=O)N1CCC(CC1)c1[nH]nc(c1-c1ccncc1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C22H23ClN4O2/c1-29-14-19(28)27-12-8-17(9-13-27)22-20(15-6-10-24-11-7-15)21(25-26-22)16-2-4-18(23)5-3-16/h2-7,10-11,17H,8-9,12-14H2,1H3,(H,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	71	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of p38alpha assessed as gamma-[33P]ATP incorporation by scintillation counting				Bioorg Med Chem Lett 20: 2634-8 (2010) Article DOI: 10.1016/j.bmcl.2010.02.047 BindingDB Entry DOI: 10.7270/Q21N818H
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50315113 (1-(4-(3-(4-chlorophenyl)-4-(pyridin-4-yl)-1H-pyraz...) Show SMILES CN(C)CC(=O)N1CCC(CC1)c1[nH]nc(c1-c1ccncc1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C23H26ClN5O/c1-28(2)15-20(30)29-13-9-18(10-14-29)23-21(16-7-11-25-12-8-16)22(26-27-23)17-3-5-19(24)6-4-17/h3-8,11-12,18H,9-10,13-15H2,1-2H3,(H,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of p38alpha assessed as gamma-[33P]ATP incorporation by scintillation counting				Bioorg Med Chem Lett 20: 2634-8 (2010) Article DOI: 10.1016/j.bmcl.2010.02.047 BindingDB Entry DOI: 10.7270/Q21N818H
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50315102 (1-(4-(3-(4-fluorophenyl)-4-(pyridin-4-yl)-1H-pyraz...) Show SMILES CC(=O)N1CCC(CC1)c1[nH]nc(c1-c1ccncc1)-c1ccc(F)cc1 Show InChI InChI=1S/C21H21FN4O/c1-14(27)26-12-8-17(9-13-26)21-19(15-6-10-23-11-7-15)20(24-25-21)16-2-4-18(22)5-3-16/h2-7,10-11,17H,8-9,12-13H2,1H3,(H,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	82	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of p38alpha assessed as gamma-[33P]ATP incorporation by scintillation counting				Bioorg Med Chem Lett 20: 2634-8 (2010) Article DOI: 10.1016/j.bmcl.2010.02.047 BindingDB Entry DOI: 10.7270/Q21N818H
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50315125 (4-(3-(4-chlorophenyl)-4-(pyrimidin-4-yl)-1H-pyrazo...) Show SMILES CN(C)C(=O)N1CCC(CC1)c1[nH]nc(c1-c1ccncn1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C21H23ClN6O/c1-27(2)21(29)28-11-8-15(9-12-28)20-18(17-7-10-23-13-24-17)19(25-26-20)14-3-5-16(22)6-4-14/h3-7,10,13,15H,8-9,11-12H2,1-2H3,(H,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	88	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of p38alpha assessed as gamma-[33P]ATP incorporation by scintillation counting				Bioorg Med Chem Lett 20: 2634-8 (2010) Article DOI: 10.1016/j.bmcl.2010.02.047 BindingDB Entry DOI: 10.7270/Q21N818H
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50315117 (1-(4-(3-(4-chlorophenyl)-4-(pyrimidin-4-yl)-1H-pyr...) Show SMILES CC(C)(O)CN1CCC(CC1)c1[nH]nc(c1-c1ccncn1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C22H26ClN5O/c1-22(2,29)13-28-11-8-16(9-12-28)21-19(18-7-10-24-14-25-18)20(26-27-21)15-3-5-17(23)6-4-15/h3-7,10,14,16,29H,8-9,11-13H2,1-2H3,(H,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	88	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of p38alpha assessed as gamma-[33P]ATP incorporation by scintillation counting				Bioorg Med Chem Lett 20: 2634-8 (2010) Article DOI: 10.1016/j.bmcl.2010.02.047 BindingDB Entry DOI: 10.7270/Q21N818H
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50315128 (4-(3-(4-fluorophenyl)-5-(1-methylpiperidin-3-yl)-1...) Show SMILES CN1CCCC(C1)c1[nH]nc(c1-c1ccncc1)-c1ccc(F)cc1 Show InChI InChI=1S/C20H21FN4/c1-25-12-2-3-16(13-25)20-18(14-8-10-22-11-9-14)19(23-24-20)15-4-6-17(21)7-5-15/h4-11,16H,2-3,12-13H2,1H3,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of p38alpha assessed as gamma-[33P]ATP incorporation by scintillation counting				Bioorg Med Chem Lett 20: 2634-8 (2010) Article DOI: 10.1016/j.bmcl.2010.02.047 BindingDB Entry DOI: 10.7270/Q21N818H
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50315124 (1-(4-(3-(4-chlorophenyl)-4-(pyrimidin-4-yl)-1H-pyr...) Show SMILES COCC(=O)N1CCC(CC1)c1[nH]nc(c1-c1ccncn1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C21H22ClN5O2/c1-29-12-18(28)27-10-7-15(8-11-27)21-19(17-6-9-23-13-24-17)20(25-26-21)14-2-4-16(22)5-3-14/h2-6,9,13,15H,7-8,10-12H2,1H3,(H,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	94	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of p38alpha assessed as gamma-[33P]ATP incorporation by scintillation counting				Bioorg Med Chem Lett 20: 2634-8 (2010) Article DOI: 10.1016/j.bmcl.2010.02.047 BindingDB Entry DOI: 10.7270/Q21N818H
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50315135 (4-(5-(1-methylpiperidin-4-yl)-3-p-tolyl-1H-pyrazol...) Show SMILES CN1CCC(CC1)c1[nH]nc(c1-c1ccncc1)-c1ccc(C)cc1 Show InChI InChI=1S/C21H24N4/c1-15-3-5-17(6-4-15)20-19(16-7-11-22-12-8-16)21(24-23-20)18-9-13-25(2)14-10-18/h3-8,11-12,18H,9-10,13-14H2,1-2H3,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	99.6	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of p38alpha assessed as gamma-[33P]ATP incorporation by scintillation counting				Bioorg Med Chem Lett 20: 2634-8 (2010) Article DOI: 10.1016/j.bmcl.2010.02.047 BindingDB Entry DOI: 10.7270/Q21N818H
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50315106 (4-(3-(4-chlorophenyl)-5-(1-(3-methoxypropyl)piperi...) Show SMILES COCCCN1CCC(CC1)c1[nH]nc(c1-c1ccncc1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C23H27ClN4O/c1-29-16-2-13-28-14-9-19(10-15-28)23-21(17-7-11-25-12-8-17)22(26-27-23)18-3-5-20(24)6-4-18/h3-8,11-12,19H,2,9-10,13-16H2,1H3,(H,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	106	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of p38alpha assessed as gamma-[33P]ATP incorporation by scintillation counting				Bioorg Med Chem Lett 20: 2634-8 (2010) Article DOI: 10.1016/j.bmcl.2010.02.047 BindingDB Entry DOI: 10.7270/Q21N818H
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50315123 (1-(4-(3-(4-chlorophenyl)-4-(pyrimidin-4-yl)-1H-pyr...) Show SMILES OCC(=O)N1CCC(CC1)c1[nH]nc(c1-c1ccncn1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C20H20ClN5O2/c21-15-3-1-13(2-4-15)19-18(16-5-8-22-12-23-16)20(25-24-19)14-6-9-26(10-7-14)17(28)11-27/h1-5,8,12,14,27H,6-7,9-11H2,(H,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid UniChem Patents Similars	MMDB Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of p38alpha assessed as gamma-[33P]ATP incorporation by scintillation counting				Bioorg Med Chem Lett 20: 2634-8 (2010) Article DOI: 10.1016/j.bmcl.2010.02.047 BindingDB Entry DOI: 10.7270/Q21N818H
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50315111 (1-(4-(3-(4-chlorophenyl)-4-(pyridin-4-yl)-1H-pyraz...) Show SMILES OCC(=O)N1CCC(CC1)c1[nH]nc(c1-c1ccncc1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C21H21ClN4O2/c22-17-3-1-15(2-4-17)20-19(14-5-9-23-10-6-14)21(25-24-20)16-7-11-26(12-8-16)18(28)13-27/h1-6,9-10,16,27H,7-8,11-13H2,(H,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	111	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of p38alpha assessed as gamma-[33P]ATP incorporation by scintillation counting				Bioorg Med Chem Lett 20: 2634-8 (2010) Article DOI: 10.1016/j.bmcl.2010.02.047 BindingDB Entry DOI: 10.7270/Q21N818H
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50315109 (2-(4-(3-(4-chlorophenyl)-4-(pyridin-4-yl)-1H-pyraz...) Show SMILES OC(=O)CN1CCC(CC1)c1[nH]nc(c1-c1ccncc1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C21H21ClN4O2/c22-17-3-1-15(2-4-17)20-19(14-5-9-23-10-6-14)21(25-24-20)16-7-11-26(12-8-16)13-18(27)28/h1-6,9-10,16H,7-8,11-13H2,(H,24,25)(H,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	126	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of p38alpha assessed as gamma-[33P]ATP incorporation by scintillation counting				Bioorg Med Chem Lett 20: 2634-8 (2010) Article DOI: 10.1016/j.bmcl.2010.02.047 BindingDB Entry DOI: 10.7270/Q21N818H
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50315122 (1-(4-(3-(4-chlorophenyl)-4-(pyrimidin-4-yl)-1H-pyr...) Show SMILES CC(=O)N1CCC(CC1)c1[nH]nc(c1-c1ccncn1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C20H20ClN5O/c1-13(27)26-10-7-15(8-11-26)20-18(17-6-9-22-12-23-17)19(24-25-20)14-2-4-16(21)5-3-14/h2-6,9,12,15H,7-8,10-11H2,1H3,(H,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	152	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of p38alpha assessed as gamma-[33P]ATP incorporation by scintillation counting				Bioorg Med Chem Lett 20: 2634-8 (2010) Article DOI: 10.1016/j.bmcl.2010.02.047 BindingDB Entry DOI: 10.7270/Q21N818H
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 11 (Homo sapiens (Human))	BDBM50315134 (4-(5-(1-methylpiperidin-4-yl)-3-(3-(trifluoromethy...) Show SMILES CN1CCC(CC1)c1[nH]nc(c1-c1ccncc1)-c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C21H21F3N4/c1-28-11-7-15(8-12-28)19-18(14-5-9-25-10-6-14)20(27-26-19)16-3-2-4-17(13-16)21(22,23)24/h2-6,9-10,13,15H,7-8,11-12H2,1H3,(H,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	164	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of p38beta assessed as gamma-[33P]ATP incorporation by scintillation counting				Bioorg Med Chem Lett 20: 2634-8 (2010) Article DOI: 10.1016/j.bmcl.2010.02.047 BindingDB Entry DOI: 10.7270/Q21N818H
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50315116 (2-(4-(3-(4-chlorophenyl)-4-(pyrimidin-4-yl)-1H-pyr...) Show SMILES CC(C)(CO)N1CCC(CC1)c1[nH]nc(c1-c1ccncn1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C22H26ClN5O/c1-22(2,13-29)28-11-8-16(9-12-28)21-19(18-7-10-24-14-25-18)20(26-27-21)15-3-5-17(23)6-4-15/h3-7,10,14,16,29H,8-9,11-13H2,1-2H3,(H,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	184	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of p38alpha assessed as gamma-[33P]ATP incorporation by scintillation counting				Bioorg Med Chem Lett 20: 2634-8 (2010) Article DOI: 10.1016/j.bmcl.2010.02.047 BindingDB Entry DOI: 10.7270/Q21N818H
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50315126 (4-(3-(4-chlorophenyl)-5-(1-(methylsulfonyl)piperid...) Show SMILES CS(=O)(=O)N1CCC(CC1)c1[nH]nc(c1-c1ccncn1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C19H20ClN5O2S/c1-28(26,27)25-10-7-14(8-11-25)19-17(16-6-9-21-12-22-16)18(23-24-19)13-2-4-15(20)5-3-13/h2-6,9,12,14H,7-8,10-11H2,1H3,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	198	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of p38alpha assessed as gamma-[33P]ATP incorporation by scintillation counting				Bioorg Med Chem Lett 20: 2634-8 (2010) Article DOI: 10.1016/j.bmcl.2010.02.047 BindingDB Entry DOI: 10.7270/Q21N818H
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50315119 (4-(3-(4-chlorophenyl)-5-(1-(tetrahydro-2H-pyran-4-...) Show SMILES Clc1ccc(cc1)-c1n[nH]c(C2CCN(CC2)C2CCOCC2)c1-c1ccncn1 Show InChI InChI=1S/C23H26ClN5O/c24-18-3-1-16(2-4-18)22-21(20-5-10-25-15-26-20)23(28-27-22)17-6-11-29(12-7-17)19-8-13-30-14-9-19/h1-5,10,15,17,19H,6-9,11-14H2,(H,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	205	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of p38alpha assessed as gamma-[33P]ATP incorporation by scintillation counting				Bioorg Med Chem Lett 20: 2634-8 (2010) Article DOI: 10.1016/j.bmcl.2010.02.047 BindingDB Entry DOI: 10.7270/Q21N818H
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 11 (Homo sapiens (Human))	BDBM50315127 (4-(3-(4-fluorophenyl)-5-(piperidin-3-yl)-1H-pyrazo...) Show SMILES Fc1ccc(cc1)-c1n[nH]c(C2CCCNC2)c1-c1ccncc1 Show InChI InChI=1S/C19H19FN4/c20-16-5-3-14(4-6-16)18-17(13-7-10-21-11-8-13)19(24-23-18)15-2-1-9-22-12-15/h3-8,10-11,15,22H,1-2,9,12H2,(H,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	404	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of p38beta assessed as gamma-[33P]ATP incorporation by scintillation counting				Bioorg Med Chem Lett 20: 2634-8 (2010) Article DOI: 10.1016/j.bmcl.2010.02.047 BindingDB Entry DOI: 10.7270/Q21N818H
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 11 (Homo sapiens (Human))	BDBM50315129 (4-(3-(4-fluorophenyl)-5-(piperidin-4-yl)-1H-pyrazo...) Show SMILES Fc1ccc(cc1)-c1n[nH]c(C2CCNCC2)c1-c1ccncc1 Show InChI InChI=1S/C19H19FN4/c20-16-3-1-14(2-4-16)18-17(13-5-9-21-10-6-13)19(24-23-18)15-7-11-22-12-8-15/h1-6,9-10,15,22H,7-8,11-12H2,(H,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	510	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of p38beta assessed as gamma-[33P]ATP incorporation by scintillation counting				Bioorg Med Chem Lett 20: 2634-8 (2010) Article DOI: 10.1016/j.bmcl.2010.02.047 BindingDB Entry DOI: 10.7270/Q21N818H
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50315102 (1-(4-(3-(4-fluorophenyl)-4-(pyridin-4-yl)-1H-pyraz...) Show SMILES CC(=O)N1CCC(CC1)c1[nH]nc(c1-c1ccncc1)-c1ccc(F)cc1 Show InChI InChI=1S/C21H21FN4O/c1-14(27)26-12-8-17(9-13-26)21-19(15-6-10-23-11-7-15)20(24-25-21)16-2-4-18(22)5-3-16/h2-7,10-11,17H,8-9,12-13H2,1H3,(H,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	790	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human ERG by patch clamp technique				Bioorg Med Chem Lett 20: 2634-8 (2010) Article DOI: 10.1016/j.bmcl.2010.02.047 BindingDB Entry DOI: 10.7270/Q21N818H
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 11 (Homo sapiens (Human))	BDBM50315132 (4-(3-(3-chlorophenyl)-5-(1-methylpiperidin-4-yl)-1...) Show SMILES CN1CCC(CC1)c1[nH]nc(c1-c1ccncc1)-c1cccc(Cl)c1 Show InChI InChI=1S/C20H21ClN4/c1-25-11-7-15(8-12-25)19-18(14-5-9-22-10-6-14)20(24-23-19)16-3-2-4-17(21)13-16/h2-6,9-10,13,15H,7-8,11-12H2,1H3,(H,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.05E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of p38beta assessed as gamma-[33P]ATP incorporation by scintillation counting				Bioorg Med Chem Lett 20: 2634-8 (2010) Article DOI: 10.1016/j.bmcl.2010.02.047 BindingDB Entry DOI: 10.7270/Q21N818H
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 11 (Homo sapiens (Human))	BDBM50315107 (4-(3-(4-chlorophenyl)-4-(pyridin-4-yl)-1H-pyrazol-...) Show SMILES NS(=O)(=O)N1CCC(CC1)c1[nH]nc(c1-c1ccncc1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C19H20ClN5O2S/c20-16-3-1-14(2-4-16)18-17(13-5-9-22-10-6-13)19(24-23-18)15-7-11-25(12-8-15)28(21,26)27/h1-6,9-10,15H,7-8,11-12H2,(H,23,24)(H2,21,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.65E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of p38beta assessed as gamma-[33P]ATP incorporation by scintillation counting				Bioorg Med Chem Lett 20: 2634-8 (2010) Article DOI: 10.1016/j.bmcl.2010.02.047 BindingDB Entry DOI: 10.7270/Q21N818H
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 11 (Homo sapiens (Human))	BDBM50315102 (1-(4-(3-(4-fluorophenyl)-4-(pyridin-4-yl)-1H-pyraz...) Show SMILES CC(=O)N1CCC(CC1)c1[nH]nc(c1-c1ccncc1)-c1ccc(F)cc1 Show InChI InChI=1S/C21H21FN4O/c1-14(27)26-12-8-17(9-13-26)21-19(15-6-10-23-11-7-15)20(24-25-21)16-2-4-18(22)5-3-16/h2-7,10-11,17H,8-9,12-13H2,1H3,(H,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.68E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of p38beta assessed as gamma-[33P]ATP incorporation by scintillation counting				Bioorg Med Chem Lett 20: 2634-8 (2010) Article DOI: 10.1016/j.bmcl.2010.02.047 BindingDB Entry DOI: 10.7270/Q21N818H
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 11 (Homo sapiens (Human))	BDBM50315111 (1-(4-(3-(4-chlorophenyl)-4-(pyridin-4-yl)-1H-pyraz...) Show SMILES OCC(=O)N1CCC(CC1)c1[nH]nc(c1-c1ccncc1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C21H21ClN4O2/c22-17-3-1-15(2-4-17)20-19(14-5-9-23-10-6-14)21(25-24-20)16-7-11-26(12-8-16)18(28)13-27/h1-6,9-10,16,27H,7-8,11-13H2,(H,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.79E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of p38beta assessed as gamma-[33P]ATP incorporation by scintillation counting				Bioorg Med Chem Lett 20: 2634-8 (2010) Article DOI: 10.1016/j.bmcl.2010.02.047 BindingDB Entry DOI: 10.7270/Q21N818H
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 11 (Homo sapiens (Human))	BDBM50315130 (4-(3-(4-fluorophenyl)-5-(1-methylpiperidin-4-yl)-1...) Show SMILES CN1CCC(CC1)c1[nH]nc(c1-c1ccncc1)-c1ccc(F)cc1 Show InChI InChI=1S/C20H21FN4/c1-25-12-8-16(9-13-25)20-18(14-6-10-22-11-7-14)19(23-24-20)15-2-4-17(21)5-3-15/h2-7,10-11,16H,8-9,12-13H2,1H3,(H,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.96E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of p38beta assessed as gamma-[33P]ATP incorporation by scintillation counting				Bioorg Med Chem Lett 20: 2634-8 (2010) Article DOI: 10.1016/j.bmcl.2010.02.047 BindingDB Entry DOI: 10.7270/Q21N818H
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 11 (Homo sapiens (Human))	BDBM50315114 (4-(3-(4-chlorophenyl)-5-(1-methylpiperidin-4-yl)-1...) Show SMILES CN1CCC(CC1)c1[nH]nc(c1-c1ccncn1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C19H20ClN5/c1-25-10-7-14(8-11-25)19-17(16-6-9-21-12-22-16)18(23-24-19)13-2-4-15(20)5-3-13/h2-6,9,12,14H,7-8,10-11H2,1H3,(H,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.32E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of p38beta assessed as gamma-[33P]ATP incorporation by scintillation counting				Bioorg Med Chem Lett 20: 2634-8 (2010) Article DOI: 10.1016/j.bmcl.2010.02.047 BindingDB Entry DOI: 10.7270/Q21N818H
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 11 (Homo sapiens (Human))	BDBM50315103 (4-(5-(1-methylpiperidin-4-yl)-3-m-tolyl-1H-pyrazol...) Show SMILES CN1CCC(CC1)c1[nH]nc(c1-c1ccncc1)-c1cccc(C)c1 Show InChI InChI=1S/C21H24N4/c1-15-4-3-5-18(14-15)21-19(16-6-10-22-11-7-16)20(23-24-21)17-8-12-25(2)13-9-17/h3-7,10-11,14,17H,8-9,12-13H2,1-2H3,(H,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.35E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of p38beta assessed as gamma-[33P]ATP incorporation by scintillation counting				Bioorg Med Chem Lett 20: 2634-8 (2010) Article DOI: 10.1016/j.bmcl.2010.02.047 BindingDB Entry DOI: 10.7270/Q21N818H
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 11 (Homo sapiens (Human))	BDBM50315128 (4-(3-(4-fluorophenyl)-5-(1-methylpiperidin-3-yl)-1...) Show SMILES CN1CCCC(C1)c1[nH]nc(c1-c1ccncc1)-c1ccc(F)cc1 Show InChI InChI=1S/C20H21FN4/c1-25-12-2-3-16(13-25)20-18(14-8-10-22-11-9-14)19(23-24-20)15-4-6-17(21)7-5-15/h4-11,16H,2-3,12-13H2,1H3,(H,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.52E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of p38beta assessed as gamma-[33P]ATP incorporation by scintillation counting				Bioorg Med Chem Lett 20: 2634-8 (2010) Article DOI: 10.1016/j.bmcl.2010.02.047 BindingDB Entry DOI: 10.7270/Q21N818H
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 11 (Homo sapiens (Human))	BDBM50315115 (2-(4-(3-(4-chlorophenyl)-4-(pyrimidin-4-yl)-1H-pyr...) Show SMILES OCCN1CCC(CC1)c1[nH]nc(c1-c1ccncn1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C20H22ClN5O/c21-16-3-1-14(2-4-16)19-18(17-5-8-22-13-23-17)20(25-24-19)15-6-9-26(10-7-15)11-12-27/h1-5,8,13,15,27H,6-7,9-12H2,(H,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.54E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of p38beta assessed as gamma-[33P]ATP incorporation by scintillation counting				Bioorg Med Chem Lett 20: 2634-8 (2010) Article DOI: 10.1016/j.bmcl.2010.02.047 BindingDB Entry DOI: 10.7270/Q21N818H
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 11 (Homo sapiens (Human))	BDBM50315131 (4-(3-(4-chlorophenyl)-5-(1-methylpiperidin-4-yl)-1...) Show SMILES CN1CCC(CC1)c1[nH]nc(c1-c1ccncc1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C20H21ClN4/c1-25-12-8-16(9-13-25)20-18(14-6-10-22-11-7-14)19(23-24-20)15-2-4-17(21)5-3-15/h2-7,10-11,16H,8-9,12-13H2,1H3,(H,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.68E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of p38beta assessed as gamma-[33P]ATP incorporation by scintillation counting				Bioorg Med Chem Lett 20: 2634-8 (2010) Article DOI: 10.1016/j.bmcl.2010.02.047 BindingDB Entry DOI: 10.7270/Q21N818H
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 11 (Homo sapiens (Human))	BDBM50315116 (2-(4-(3-(4-chlorophenyl)-4-(pyrimidin-4-yl)-1H-pyr...) Show SMILES CC(C)(CO)N1CCC(CC1)c1[nH]nc(c1-c1ccncn1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C22H26ClN5O/c1-22(2,13-29)28-11-8-16(9-12-28)21-19(18-7-10-24-14-25-18)20(26-27-21)15-3-5-17(23)6-4-15/h3-7,10,14,16,29H,8-9,11-13H2,1-2H3,(H,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.78E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of p38beta assessed as gamma-[33P]ATP incorporation by scintillation counting				Bioorg Med Chem Lett 20: 2634-8 (2010) Article DOI: 10.1016/j.bmcl.2010.02.047 BindingDB Entry DOI: 10.7270/Q21N818H
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 11 (Homo sapiens (Human))	BDBM50315135 (4-(5-(1-methylpiperidin-4-yl)-3-p-tolyl-1H-pyrazol...) Show SMILES CN1CCC(CC1)c1[nH]nc(c1-c1ccncc1)-c1ccc(C)cc1 Show InChI InChI=1S/C21H24N4/c1-15-3-5-17(6-4-15)20-19(16-7-11-22-12-8-16)21(24-23-20)18-9-13-25(2)14-10-18/h3-8,11-12,18H,9-10,13-14H2,1-2H3,(H,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.07E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of p38beta assessed as gamma-[33P]ATP incorporation by scintillation counting				Bioorg Med Chem Lett 20: 2634-8 (2010) Article DOI: 10.1016/j.bmcl.2010.02.047 BindingDB Entry DOI: 10.7270/Q21N818H
					More data for this Ligand-Target Pair

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