Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Integrin alpha-L/beta-2 (Homo sapiens (Human)) | BDBM50154483 ((R)-3-(4-Bromo-benzyl)-1-(3,5-dichloro-phenyl)-5-(...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL | Assay Description Dissociation constant for human Lymphocyte function associated antigen 1 in LFA-1/ICAM-1 binding assay | J Med Chem 47: 5356-66 (2004) Article DOI: 10.1021/jm049657b BindingDB Entry DOI: 10.7270/Q2B857MB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-L/beta-2 (Homo sapiens (Human)) | BDBM50154483 ((R)-3-(4-Bromo-benzyl)-1-(3,5-dichloro-phenyl)-5-(...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL | Assay Description Dissociation constant for human Lymphocyte function-associated antigen-1 in LFA-1/ICAM-1 binding assay | J Med Chem 47: 5356-66 (2004) Article DOI: 10.1021/jm049657b BindingDB Entry DOI: 10.7270/Q2B857MB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-L/beta-2 (Homo sapiens (Human)) | BDBM50154472 ((R)-3-(4-Bromo-benzyl)-1-(3,5-dichloro-phenyl)-3-m...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL | Assay Description Dissociation constant for human Lymphocyte function associated antigen 1 in LFA-1/ICAM-1 binding assay | J Med Chem 47: 5356-66 (2004) Article DOI: 10.1021/jm049657b BindingDB Entry DOI: 10.7270/Q2B857MB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-L/beta-2 (Homo sapiens (Human)) | BDBM50154481 (Acetic acid 3-[(R)-5-(4-bromo-benzyl)-7-(3,5-dichl...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL | Assay Description Dissociation constant for human Lymphocyte function associated antigen 1 in LFA-1/ICAM-1 binding assay | J Med Chem 47: 5356-66 (2004) Article DOI: 10.1021/jm049657b BindingDB Entry DOI: 10.7270/Q2B857MB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-L/beta-2 (Homo sapiens (Human)) | BDBM50154476 ((R)-3-(4-Bromo-benzyl)-1-(3,5-dichloro-phenyl)-5-(...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL | Assay Description Dissociation constant for human Lymphocyte function associated antigen1 in LFA-1/ICAM-1 binding assay | J Med Chem 47: 5356-66 (2004) Article DOI: 10.1021/jm049657b BindingDB Entry DOI: 10.7270/Q2B857MB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-L/beta-2 (Homo sapiens (Human)) | BDBM50154506 ((R)-3-(4-Bromo-benzyl)-1-(3,5-dichloro-phenyl)-5-(...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL | Assay Description Dissociation constant for human Lymphocyte function associated antigen 1 in LFA-1/ICAM-1 binding assay | J Med Chem 47: 5356-66 (2004) Article DOI: 10.1021/jm049657b BindingDB Entry DOI: 10.7270/Q2B857MB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-L/beta-2 (Homo sapiens (Human)) | BDBM50154476 ((R)-3-(4-Bromo-benzyl)-1-(3,5-dichloro-phenyl)-5-(...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL | Assay Description Dissociation constant for human Lymphocyte function associated antigen 1 in LFA-1/ICAM-1 binding assay | J Med Chem 47: 5356-66 (2004) Article DOI: 10.1021/jm049657b BindingDB Entry DOI: 10.7270/Q2B857MB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-L/beta-2 (Homo sapiens (Human)) | BDBM50154489 ((R)-3-(4-Bromo-benzyl)-1-(3,5-dichloro-phenyl)-3-m...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL | Assay Description Dissociation constant for human Lymphocyte function associated antigen 1 in LFA-1/ICAM-1 binding assay | J Med Chem 47: 5356-66 (2004) Article DOI: 10.1021/jm049657b BindingDB Entry DOI: 10.7270/Q2B857MB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-L/beta-2 (Homo sapiens (Human)) | BDBM50538002 (CHEMBL1233907) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a |
Pliant Therapeutics Curated by ChEMBL | Assay Description Binding affinity to human lymphocyte integrin alphaL beta2 (Cys125 to Gly311residues) expressed in Escherichia coli XL-1B cells by isothermal titrati... | J Med Chem 63: 5675-5696 (2020) Article DOI: 10.1021/acs.jmedchem.9b01869 BindingDB Entry DOI: 10.7270/Q2DR302Z | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Integrin alpha-L/beta-2 (Homo sapiens (Human)) | BDBM50154478 ((R)-3-(4-Bromo-benzyl)-1-(3,5-dichloro-phenyl)-5-(...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL | Assay Description Dissociation constant for human Lymphocyte function associated antigen 1 in LFA-1/ICAM-1 binding assay | J Med Chem 47: 5356-66 (2004) Article DOI: 10.1021/jm049657b BindingDB Entry DOI: 10.7270/Q2B857MB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-L/beta-2 (Homo sapiens (Human)) | BDBM50154480 ((R)-3-(4-Bromo-benzyl)-1-(3,5-dichloro-phenyl)-3-m...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL | Assay Description Dissociation constant for human Lymphocyte function associated antigen 1 in LFA-1/ICAM-1 binding assay | J Med Chem 47: 5356-66 (2004) Article DOI: 10.1021/jm049657b BindingDB Entry DOI: 10.7270/Q2B857MB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-L/beta-2 (Homo sapiens (Human)) | BDBM50154496 ((R)-5-(4-Bromo-benzyl)-3-(3,5-dichloro-phenyl)-1,5...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL | Assay Description Dissociation constant for human Lymphocyte function associated antigen 1 in LFA-1/ICAM-1 binding assay | J Med Chem 47: 5356-66 (2004) Article DOI: 10.1021/jm049657b BindingDB Entry DOI: 10.7270/Q2B857MB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-L/beta-2 (Homo sapiens (Human)) | BDBM50154492 (CHEMBL188615 | N-{3-[(R)-5-(4-Bromo-benzyl)-7-(3,5...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL | Assay Description Dissociation constant for human Lymphocyte function associated antigen 1 in LFA-1/ICAM-1 binding assay | J Med Chem 47: 5356-66 (2004) Article DOI: 10.1021/jm049657b BindingDB Entry DOI: 10.7270/Q2B857MB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-L/beta-2 (Homo sapiens (Human)) | BDBM50154502 (Acetic acid 4-[(R)-5-(4-bromo-benzyl)-7-(3,5-dichl...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL | Assay Description Dissociation constant for human Lymphocyte function associated antigen 1 in LFA-1/ICAM-1 binding assay | J Med Chem 47: 5356-66 (2004) Article DOI: 10.1021/jm049657b BindingDB Entry DOI: 10.7270/Q2B857MB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-L/beta-2 (Homo sapiens (Human)) | BDBM50154483 ((R)-3-(4-Bromo-benzyl)-1-(3,5-dichloro-phenyl)-5-(...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL | Assay Description Dissociation constant against human Lymphocyte function associated antigen1 in LFA-1/ICAM-1 binding assay | J Med Chem 47: 5356-66 (2004) Article DOI: 10.1021/jm049657b BindingDB Entry DOI: 10.7270/Q2B857MB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-L/beta-2 (Homo sapiens (Human)) | BDBM50154501 (5-(4-Bromo-benzyl)-7-(3,5-dichloro-phenyl)-5-methy...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL | Assay Description Dissociation constant for human Lymphocyte function associated antigen 1 in LFA-1/ICAM-1 binding assay | J Med Chem 47: 5356-66 (2004) Article DOI: 10.1021/jm049657b BindingDB Entry DOI: 10.7270/Q2B857MB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-L/beta-2 (Homo sapiens (Human)) | BDBM50154481 (Acetic acid 3-[(R)-5-(4-bromo-benzyl)-7-(3,5-dichl...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL | Assay Description Dissociation constant against human Lymphocyte function associated antigen1 in LFA-1/ICAM-1 binding assay | J Med Chem 47: 5356-66 (2004) Article DOI: 10.1021/jm049657b BindingDB Entry DOI: 10.7270/Q2B857MB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-L/beta-2 (Homo sapiens (Human)) | BDBM50154494 ((R)-3-(4-Bromo-benzyl)-1-(3,5-dichloro-phenyl)-5-(...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL | Assay Description Dissociation constant for human Lymphocyte function associated antigen 1 in LFA-1/ICAM-1 binding assay | J Med Chem 47: 5356-66 (2004) Article DOI: 10.1021/jm049657b BindingDB Entry DOI: 10.7270/Q2B857MB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-L/beta-2 (Homo sapiens (Human)) | BDBM50154477 ((R)-3-(4-Bromo-benzyl)-1-(3,5-dichloro-phenyl)-5-m...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL | Assay Description Dissociation constant for human Lymphocyte function associated antigen 1 in LFA-1/ICAM-1 binding assay | J Med Chem 47: 5356-66 (2004) Article DOI: 10.1021/jm049657b BindingDB Entry DOI: 10.7270/Q2B857MB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-L/beta-2 (Homo sapiens (Human)) | BDBM50154498 ((R)-3-(4-Bromo-benzyl)-1-(3,5-dichloro-phenyl)-3-m...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL | Assay Description Dissociation constant for human Lymphocyte function associated antigen 1 in LFA-1/ICAM-1 binding assay | J Med Chem 47: 5356-66 (2004) Article DOI: 10.1021/jm049657b BindingDB Entry DOI: 10.7270/Q2B857MB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-L/beta-2 (Homo sapiens (Human)) | BDBM50154488 ((R)-3-(4-Bromo-benzyl)-1-(3,5-dichloro-phenyl)-3-m...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL | Assay Description Dissociation constant for human Lymphocyte function associated antigen 1 in LFA-1/ICAM-1 binding assay | J Med Chem 47: 5356-66 (2004) Article DOI: 10.1021/jm049657b BindingDB Entry DOI: 10.7270/Q2B857MB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-L/beta-2 (Homo sapiens (Human)) | BDBM50154475 (3-(4-Bromo-benzyl)-1-(3,5-dichloro-phenyl)-5-metha...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 70 | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL | Assay Description Dissociation constant for human Lymphocyte function associated antigen 1 in LFA-1/ICAM-1 binding assay | J Med Chem 47: 5356-66 (2004) Article DOI: 10.1021/jm049657b BindingDB Entry DOI: 10.7270/Q2B857MB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-L/beta-2 (Homo sapiens (Human)) | BDBM50154504 ((R)-3-(4-Bromo-benzyl)-1-(3,5-dichloro-phenyl)-5-(...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 70 | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL | Assay Description Dissociation constant for human Lymphocyte function associated antigen 1 in LFA-1/ICAM-1 binding assay | J Med Chem 47: 5356-66 (2004) Article DOI: 10.1021/jm049657b BindingDB Entry DOI: 10.7270/Q2B857MB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-L/beta-2 (Homo sapiens (Human)) | BDBM50154492 (CHEMBL188615 | N-{3-[(R)-5-(4-Bromo-benzyl)-7-(3,5...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 70 | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL | Assay Description Dissociation constant against human Lymphocyte function associated antigen1 in LFA-1/ICAM-1 binding assay | J Med Chem 47: 5356-66 (2004) Article DOI: 10.1021/jm049657b BindingDB Entry DOI: 10.7270/Q2B857MB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-L/beta-2 (Homo sapiens (Human)) | BDBM50154476 ((R)-3-(4-Bromo-benzyl)-1-(3,5-dichloro-phenyl)-5-(...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL | Assay Description Dissociation constant against human Lymphocyte function associated antigen1 in LFA-1/ICAM-1 binding assay | J Med Chem 47: 5356-66 (2004) Article DOI: 10.1021/jm049657b BindingDB Entry DOI: 10.7270/Q2B857MB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-L/beta-2 (Homo sapiens (Human)) | BDBM50154486 (6-(4-Bromo-benzyl)-4-(3,5-dichloro-phenyl)-6-methy...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL | Assay Description Dissociation constant for human Lymphocyte function associated antigen 1 in LFA-1/ICAM-1 binding assay | J Med Chem 47: 5356-66 (2004) Article DOI: 10.1021/jm049657b BindingDB Entry DOI: 10.7270/Q2B857MB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-L/beta-2 (Homo sapiens (Human)) | BDBM50154503 ((R)-3-(4-Bromo-benzyl)-1-(3,5-dichloro-phenyl)-3-m...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL | Assay Description Dissociation constant for human Lymphocyte function associated antigen 1 in LFA-1/ICAM-1 binding assay | J Med Chem 47: 5356-66 (2004) Article DOI: 10.1021/jm049657b BindingDB Entry DOI: 10.7270/Q2B857MB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-L/beta-2 (Homo sapiens (Human)) | BDBM50154479 ((R)-5-(3-Amino-propane-1-sulfonyl)-3-(4-bromo-benz...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 170 | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL | Assay Description Dissociation constant for human Lymphocyte function associated antigen 1 in LFA-1/ICAM-1 binding assay | J Med Chem 47: 5356-66 (2004) Article DOI: 10.1021/jm049657b BindingDB Entry DOI: 10.7270/Q2B857MB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-L/beta-2 (Homo sapiens (Human)) | BDBM50154505 (5-Bromo-3-(4-bromo-benzyl)-1-(3,5-dichloro-phenyl)...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL | Assay Description Dissociation constant for human Lymphocyte function associated antigen 1 in LFA-1/ICAM-1 binding assay | J Med Chem 47: 5356-66 (2004) Article DOI: 10.1021/jm049657b BindingDB Entry DOI: 10.7270/Q2B857MB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-L/beta-2 (Homo sapiens (Human)) | BDBM50154482 (5-(4-Bromo-benzyl)-7-(3,5-dichloro-phenyl)-5-methy...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 190 | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL | Assay Description Dissociation constant for human Lymphocyte function associated antigen 1 in LFA-1/ICAM-1 binding assay | J Med Chem 47: 5356-66 (2004) Article DOI: 10.1021/jm049657b BindingDB Entry DOI: 10.7270/Q2B857MB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-L/beta-2 (Homo sapiens (Human)) | BDBM50154491 (5-Acetyl-3-(4-bromo-benzyl)-1-(3,5-dichloro-phenyl...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 240 | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL | Assay Description Dissociation constant for human Lymphocyte function associated antigen 1 in LFA-1/ICAM-1 binding assay | J Med Chem 47: 5356-66 (2004) Article DOI: 10.1021/jm049657b BindingDB Entry DOI: 10.7270/Q2B857MB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-L/beta-2 (Homo sapiens (Human)) | BDBM50154497 (5-(4-Bromo-benzyl)-7-(3,5-dichloro-phenyl)-5-methy...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 280 | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL | Assay Description Dissociation constant for human Lymphocyte function associated antigen 1 in LFA-1/ICAM-1 binding assay | J Med Chem 47: 5356-66 (2004) Article DOI: 10.1021/jm049657b BindingDB Entry DOI: 10.7270/Q2B857MB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-L/beta-2 (Homo sapiens (Human)) | BDBM50154472 ((R)-3-(4-Bromo-benzyl)-1-(3,5-dichloro-phenyl)-3-m...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL | Assay Description Dissociation constant against human Lymphocyte function associated antigen1 in LFA-1/ICAM-1 binding assay | J Med Chem 47: 5356-66 (2004) Article DOI: 10.1021/jm049657b BindingDB Entry DOI: 10.7270/Q2B857MB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-L/beta-2 (Homo sapiens (Human)) | BDBM50154499 (3-(4-Bromo-benzyl)-1-(3,5-dichloro-phenyl)-3,5-dim...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 340 | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL | Assay Description Dissociation constant for human Lymphocyte function associated antigen 1 in LFA-1/ICAM-1 binding assay | J Med Chem 47: 5356-66 (2004) Article DOI: 10.1021/jm049657b BindingDB Entry DOI: 10.7270/Q2B857MB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-L/beta-2 (Homo sapiens (Human)) | BDBM50154485 (3-(4-Bromo-benzyl)-1-(3,5-dichloro-phenyl)-5-metho...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 360 | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL | Assay Description Dissociation constant for human Lymphocyte function associated antigen 1 in LFA-1/ICAM-1 binding assay | J Med Chem 47: 5356-66 (2004) Article DOI: 10.1021/jm049657b BindingDB Entry DOI: 10.7270/Q2B857MB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-L/beta-2 (Homo sapiens (Human)) | BDBM50154490 (3-(4-Bromo-benzyl)-1-(3,5-dichloro-phenyl)-3-methy...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 380 | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL | Assay Description Dissociation constant for human Lymphocyte function associated antigen 1 in LFA-1/ICAM-1 binding assay | J Med Chem 47: 5356-66 (2004) Article DOI: 10.1021/jm049657b BindingDB Entry DOI: 10.7270/Q2B857MB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-L/beta-2 (Homo sapiens (Human)) | BDBM50154488 ((R)-3-(4-Bromo-benzyl)-1-(3,5-dichloro-phenyl)-3-m...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL | Assay Description Dissociation constant against human Lymphocyte function associated antigen1 in LFA-1/ICAM-1 binding assay | J Med Chem 47: 5356-66 (2004) Article DOI: 10.1021/jm049657b BindingDB Entry DOI: 10.7270/Q2B857MB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-L/beta-2 (Homo sapiens (Human)) | BDBM50154474 (3-(4-Bromo-benzyl)-1-(3,5-dichloro-phenyl)-5-iodo-...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 410 | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL | Assay Description Dissociation constant for human Lymphocyte function associated antigen 1 in LFA-1/ICAM-1 binding assay | J Med Chem 47: 5356-66 (2004) Article DOI: 10.1021/jm049657b BindingDB Entry DOI: 10.7270/Q2B857MB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-L/beta-2 (Homo sapiens (Human)) | BDBM50154473 (6-Bromo-3-(4-bromo-benzyl)-1-(3,5-dichloro-phenyl)...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 630 | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL | Assay Description Dissociation constant for human Lymphocyte function associated antigen 1 in LFA-1/ICAM-1 binding assay | J Med Chem 47: 5356-66 (2004) Article DOI: 10.1021/jm049657b BindingDB Entry DOI: 10.7270/Q2B857MB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-L/beta-2 (Homo sapiens (Human)) | BDBM50154484 (3-Benzyl-1-(3,5-dichloro-phenyl)-3-methyl-1,3-dihy...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 760 | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL | Assay Description Dissociation constant for human Lymphocyte function associated antigen 1 in LFA-1/ICAM-1 binding assay | J Med Chem 47: 5356-66 (2004) Article DOI: 10.1021/jm049657b BindingDB Entry DOI: 10.7270/Q2B857MB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-L/beta-2 (Homo sapiens (Human)) | BDBM50154487 (3-(4-Bromo-benzyl)-1-(3,5-dichloro-phenyl)-6-metha...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 920 | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL | Assay Description Dissociation constant for human Lymphocyte function associated antigen 1 in LFA-1/ICAM-1 binding assay | J Med Chem 47: 5356-66 (2004) Article DOI: 10.1021/jm049657b BindingDB Entry DOI: 10.7270/Q2B857MB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-L/beta-2 (Homo sapiens (Human)) | BDBM50154493 (6-Acetyl-3-(4-bromo-benzyl)-1-(3,5-dichloro-phenyl...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 1.62E+3 | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL | Assay Description Dissociation constant for human Lymphocyte function associated antigen 1 in LFA-1/ICAM-1 binding assay | J Med Chem 47: 5356-66 (2004) Article DOI: 10.1021/jm049657b BindingDB Entry DOI: 10.7270/Q2B857MB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-L/beta-2 (Homo sapiens (Human)) | BDBM50154495 ((S)-3-(4-Bromo-benzyl)-1-(3,5-dichloro-phenyl)-3-m...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | >7.00E+3 | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL | Assay Description Dissociation constant for human Lymphocyte function associated antigen 1 in LFA-1/ICAM-1 binding assay | J Med Chem 47: 5356-66 (2004) Article DOI: 10.1021/jm049657b BindingDB Entry DOI: 10.7270/Q2B857MB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-L/beta-2 (Homo sapiens (Human)) | BDBM50154500 (3-(4-Bromo-benzyl)-1-(3,5-dichloro-phenyl)-6-iodo-...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL | Assay Description Dissociation constant for human Lymphocyte function associated antigen 1 in LFA-1/ICAM-1 binding assay | J Med Chem 47: 5356-66 (2004) Article DOI: 10.1021/jm049657b BindingDB Entry DOI: 10.7270/Q2B857MB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-L/beta-2 (Homo sapiens (Human)) | BDBM50094702 (1H-indole | CHEMBL15844 | Indol | Indole, 7 | indo...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | n/a | 3.00E+5 | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Inhibition of JY-8 cell adhesion via leukocyte function associated antigen 1 (LFA-1) to ICAM-1 | J Med Chem 44: 1202-10 (2001) BindingDB Entry DOI: 10.7270/Q22Z14TP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-L/beta-2 (Homo sapiens (Human)) | BDBM50094702 (1H-indole | CHEMBL15844 | Indol | Indole, 7 | indo...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 3.00E+5 | n/a | n/a | n/a | n/a | n/a |
Sunesis Pharmaceuticals Inc. Curated by ChEMBL | Assay Description Dissociation constant for Leukocyte function associated antigen 1 (LFA-1) | J Med Chem 47: 3463-82 (2004) Article DOI: 10.1021/jm040031v BindingDB Entry DOI: 10.7270/Q2NC61ZJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-L/beta-2 (Homo sapiens (Human)) | BDBM50098763 (1-Methyl-1H-indole | CHEMBL19912) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | 1.40E+6 | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Inhibition of JY-8 cell adhesion via leukocyte function associated antigen 1 (LFA-1) to ICAM-1 | J Med Chem 44: 1202-10 (2001) BindingDB Entry DOI: 10.7270/Q22Z14TP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-L/beta-2 (Homo sapiens (Human)) | BDBM50098751 (Benzo[1,2,5]thiadiazole | CHEMBL283327) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents | PubMed | n/a | n/a | n/a | 8.00E+6 | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Inhibition of JY-8 cell adhesion via leukocyte function associated antigen 1 (LFA-1) to ICAM-1 | J Med Chem 44: 1202-10 (2001) BindingDB Entry DOI: 10.7270/Q22Z14TP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-L/beta-2 (Homo sapiens (Human)) | BDBM50098766 (2,3-Dihydro-benzo[1,4]dioxine | CHEMBL19452) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 1.00E+7 | n/a | n/a | n/a | n/a | n/a |
Sunesis Pharmaceuticals Inc. Curated by ChEMBL | Assay Description Dissociation constant for Leukocyte function associated antigen 1 (LFA-1) | J Med Chem 47: 3463-82 (2004) Article DOI: 10.1021/jm040031v BindingDB Entry DOI: 10.7270/Q2NC61ZJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-L/beta-2 (Homo sapiens (Human)) | BDBM50098766 (2,3-Dihydro-benzo[1,4]dioxine | CHEMBL19452) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | 1.00E+7 | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Inhibition of JY-8 cell adhesion via leukocyte function associated antigen 1 (LFA-1) to ICAM-1 | J Med Chem 44: 1202-10 (2001) BindingDB Entry DOI: 10.7270/Q22Z14TP | |||||||||||
More data for this Ligand-Target Pair |