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Compile Data Set for Download or QSAR

Found 372 hits of ic50 for UniProtKB: P00751   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Complement factor B


(Homo sapiens (Human))
BDBM160475
PNG
(US10093663, Example 26b | US9682968, Example-26a)
Show SMILES CCO[C@H]1CCN(Cc2c(OC)cc(C)c3[nH]ccc23)[C@@H](C1)c1ccc(cc1)C(O)=O |r|
PDB

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UniChem
US Patent
n/an/a 0.0100n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...


US Patent US9682968 (2017)


BindingDB Entry DOI: 10.7270/Q2XG9P9J
More data for this
Ligand-Target Pair
Complement factor B


(Homo sapiens (Human))
BDBM160272
PNG
(US9682968, Example-22-2b (-))
Show SMILES COc1cc(C)c2[nH]ccc2c1CN1CCC(C)(C)CC1c1ccc(cc1)C(O)=O
PDB

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Novartis AG

US Patent


Assay Description
CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...


US Patent US9682968 (2017)


BindingDB Entry DOI: 10.7270/Q2XG9P9J
More data for this
Ligand-Target Pair
Complement factor B


(Homo sapiens (Human))
BDBM159938
PNG
(US10093663, Example 17-29 | US9682968, Example-17-...)
Show SMILES COc1cc(C)c2[nH]ccc2c1CN1CCC2(CC2)CC1c1ccc(cc1)C(O)=O
PDB

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Novartis AG

US Patent


Assay Description
CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...


US Patent US9682968 (2017)


BindingDB Entry DOI: 10.7270/Q2XG9P9J
More data for this
Ligand-Target Pair
Complement factor B


(Homo sapiens (Human))
BDBM159545
PNG
(US10093663, Example 17-30 | US9682968, Example-17-...)
Show SMILES CCC1CCN(Cc2c(OC)cc(C)c3[nH]ccc23)C(C1)c1ccc(cc1)C(O)=O
PDB

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Novartis AG

US Patent


Assay Description
CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...


US Patent US9682968 (2017)


BindingDB Entry DOI: 10.7270/Q2XG9P9J
More data for this
Ligand-Target Pair
Complement factor B


(Homo sapiens (Human))
BDBM159970
PNG
(US10093663, Example 20a | US9682968, Example-20a)
Show SMILES COc1cc(C)c2[nH]ccc2c1CN1CC[C@@H](C)C[C@H]1c1ccc(cc1)C(O)=O |r|
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Novartis AG

US Patent


Assay Description
CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...


US Patent US9682968 (2017)


BindingDB Entry DOI: 10.7270/Q2XG9P9J
More data for this
Ligand-Target Pair
Complement factor B


(Homo sapiens (Human))
BDBM160485
PNG
(US9682968, Example-27-4a (+))
Show SMILES CCOC1CCN(Cc2c(cc(C)c3[nH]ccc23)C2CC2)C(C1)c1ccc(cc1)C(O)=O
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Novartis AG

US Patent


Assay Description
CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...


US Patent US9682968 (2017)


BindingDB Entry DOI: 10.7270/Q2XG9P9J
More data for this
Ligand-Target Pair
Complement factor B


(Homo sapiens (Human))
BDBM160483
PNG
(US9682968, Example-27-3a (-))
Show SMILES COC1CCN(Cc2c(cc(C)c3[nH]ccc23)C2CC2)C(C1)c1ccc(cc1)C(O)=O
PDB

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Novartis AG

US Patent


Assay Description
CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...


US Patent US9682968 (2017)


BindingDB Entry DOI: 10.7270/Q2XG9P9J
More data for this
Ligand-Target Pair
Complement factor B


(Homo sapiens (Human))
BDBM159312
PNG
(US10093663, Example 17-1 | US9682968, Example-17-1)
Show SMILES Cc1cc(C2CC2)c(CN2CCCC[C@H]2c2ccc(cc2)C(O)=O)c2cc[nH]c12 |r|
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Novartis AG

US Patent


Assay Description
CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...


US Patent US9682968 (2017)


BindingDB Entry DOI: 10.7270/Q2XG9P9J
More data for this
Ligand-Target Pair
Complement factor B


(Homo sapiens (Human))
BDBM160499
PNG
(US10093663, Example 36 | US9682968, Example-36)
Show SMILES CCOC1CCN(Cc2c(OC)cc(C)c3[nH]ccc23)C(C1)c1ccc(cc1)-c1nn[nH]n1
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Novartis AG

US Patent


Assay Description
CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...


US Patent US9682968 (2017)


BindingDB Entry DOI: 10.7270/Q2XG9P9J
More data for this
Ligand-Target Pair
Complement factor B


(Homo sapiens (Human))
BDBM160500
PNG
(US10093663, Example 37 | US9682968, Example-37)
Show SMILES CCO[C@H]1CCN(Cc2c(OC)cc(C)c3[nH]ccc23)[C@@H](C1)c1ccc(cc1)C(=O)NS(C)(=O)=O |r|
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Novartis AG

US Patent


Assay Description
CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...


US Patent US9682968 (2017)


BindingDB Entry DOI: 10.7270/Q2XG9P9J
More data for this
Ligand-Target Pair
Complement factor B


(Homo sapiens (Human))
BDBM159486
PNG
(US10093663, Example 17-11 | US9682968, Example-17-...)
Show SMILES CCCO[C@H]1CCN(Cc2c(OC)cc(C)c3[nH]ccc23)[C@@H](C1)c1ccc(cc1)C(O)=O |r|
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Novartis AG

US Patent


Assay Description
CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...


US Patent US9682968 (2017)


BindingDB Entry DOI: 10.7270/Q2XG9P9J
More data for this
Ligand-Target Pair
Complement factor B


(Homo sapiens (Human))
BDBM160102
PNG
(US9682968, Example-22-1a (-))
Show SMILES CCOC1CCN(Cc2c(OC)cc(C)c3[nH]ccc23)C(C1)c1ccc(nc1)C(O)=O
PDB

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Novartis AG

US Patent


Assay Description
CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...


US Patent US9682968 (2017)


BindingDB Entry DOI: 10.7270/Q2XG9P9J
More data for this
Ligand-Target Pair
Complement factor B


(Homo sapiens (Human))
BDBM160036
PNG
(US10093663, Example 21a | US9682968, Example-21a)
Show SMILES CO[C@H]1CCN(Cc2c(OC)cc(C)c3[nH]ccc23)[C@@H](C1)c1ccc(cc1)C(O)=O |r|
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Novartis AG

US Patent


Assay Description
CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...


US Patent US9682968 (2017)


BindingDB Entry DOI: 10.7270/Q2XG9P9J
More data for this
Ligand-Target Pair
Complement factor B


(Homo sapiens (Human))
BDBM160480
PNG
(US9682968, Example-27-1b (-))
Show SMILES COC1CCN(Cc2c(C)cc(C)c3[nH]ccc23)C(C1)c1ccc(cc1)C(O)=O
PDB

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Novartis AG

US Patent


Assay Description
CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...


US Patent US9682968 (2017)


BindingDB Entry DOI: 10.7270/Q2XG9P9J
More data for this
Ligand-Target Pair
Complement factor B


(Homo sapiens (Human))
BDBM159545
PNG
(US10093663, Example 17-30 | US9682968, Example-17-...)
Show SMILES CCC1CCN(Cc2c(OC)cc(C)c3[nH]ccc23)C(C1)c1ccc(cc1)C(O)=O
PDB

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Novartis AG

US Patent


Assay Description
CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...


US Patent US9682968 (2017)


BindingDB Entry DOI: 10.7270/Q2XG9P9J
More data for this
Ligand-Target Pair
Complement factor B


(Homo sapiens (Human))
BDBM160481
PNG
(US9682968, Example-27-2a (+))
Show SMILES CCOC1CCN(Cc2c(C)cc(C)c3[nH]ccc23)C(C1)c1ccc(cc1)C(O)=O
PDB

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Novartis AG

US Patent


Assay Description
CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...


US Patent US9682968 (2017)


BindingDB Entry DOI: 10.7270/Q2XG9P9J
More data for this
Ligand-Target Pair
Complement factor B


(Homo sapiens (Human))
BDBM159319
PNG
(US9682968, Example-17-5)
Show SMILES COc1cc(C)c2[nH]ccc2c1CN1CCCC[C@H]1c1ccc(cc1)C(O)=O |r|
PDB

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Novartis AG

US Patent


Assay Description
CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...


US Patent US9682968 (2017)


BindingDB Entry DOI: 10.7270/Q2XG9P9J
More data for this
Ligand-Target Pair
Complement factor B


(Homo sapiens (Human))
BDBM159566
PNG
(US10093663, Example 17-18 | US9682968, Example-17-...)
Show SMILES COC1CCN(Cc2c(cc(C)c3[nH]ccc23)C2CC2)C(C1)c1ccc(nc1)C(O)=O
PDB

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Novartis AG

US Patent


Assay Description
CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...


US Patent US9682968 (2017)


BindingDB Entry DOI: 10.7270/Q2XG9P9J
More data for this
Ligand-Target Pair
Complement factor B


(Homo sapiens (Human))
BDBM159311
PNG
(US10093663, Example 16 | US9682968, Example-16)
Show SMILES Cc1cc(C2CC2)c(CN2CCCC[C@H]2c2ccc(C(O)=O)c(F)c2)c2cc[nH]c12 |r|
PDB

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Novartis AG

US Patent


Assay Description
CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...


US Patent US9682968 (2017)


BindingDB Entry DOI: 10.7270/Q2XG9P9J
More data for this
Ligand-Target Pair
Complement factor B


(Homo sapiens (Human))
BDBM159873
PNG
(US10093663, Example 17-24 | US9682968, Example-17-...)
Show SMILES COc1cc(C)c2[nH]ccc2c1CN1CCCC[C@H]1c1ccc(cc1)-c1cc[nH]n1 |r|
PDB

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Novartis AG

US Patent


Assay Description
CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...


US Patent US9682968 (2017)


BindingDB Entry DOI: 10.7270/Q2XG9P9J
More data for this
Ligand-Target Pair
Complement factor B


(Homo sapiens (Human))
BDBM159314
PNG
(US9682968, Example-17-3)
Show SMILES Cc1cc(C2CC2)c(CN2CCCC[C@H]2c2ccc(nc2)C(O)=O)c2cc[nH]c12 |r|
PDB

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Novartis AG

US Patent


Assay Description
CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...


US Patent US9682968 (2017)


BindingDB Entry DOI: 10.7270/Q2XG9P9J
More data for this
Ligand-Target Pair
Complement factor B


(Homo sapiens (Human))
BDBM159289
PNG
(US10093663, Example 5-12 | US9682968, Example-5-12)
Show SMILES Cc1cc(C)c2[nH]ccc2c1CN1CCCCC1c1ccc(cc1)-c1nn[nH]n1
PDB

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Novartis AG

US Patent


Assay Description
CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...


US Patent US9682968 (2017)


BindingDB Entry DOI: 10.7270/Q2XG9P9J
More data for this
Ligand-Target Pair
Complement factor B


(Homo sapiens (Human))
BDBM160474
PNG
(US9682968, Example-25b (-))
Show SMILES Cc1cc(C)c2[nH]ccc2c1CN1CCCCC1c1ccc(cc1)C(O)=O
PDB

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Novartis AG

US Patent


Assay Description
CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...


US Patent US9682968 (2017)


BindingDB Entry DOI: 10.7270/Q2XG9P9J
More data for this
Ligand-Target Pair
Complement factor B


(Homo sapiens (Human))
BDBM159920
PNG
(US10093663, Example 17-25 | US9682968, Example-17-...)
Show SMILES COc1cc(C)c2[nH]ccc2c1CN1CCCCC1c1ccc(C(O)=O)c2ccccc12
PDB

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Novartis AG

US Patent


Assay Description
CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...


US Patent US9682968 (2017)


BindingDB Entry DOI: 10.7270/Q2XG9P9J
More data for this
Ligand-Target Pair
Complement factor B


(Homo sapiens (Human))
BDBM159509
PNG
(US10093663, Example 17-13 | US9682968, Example-17-...)
Show SMILES COc1cc(C)c2[nH]ccc2c1CN1CCCCC1c1ccc(cc1C)C(O)=O
PDB

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Novartis AG

US Patent


Assay Description
CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...


US Patent US9682968 (2017)


BindingDB Entry DOI: 10.7270/Q2XG9P9J
More data for this
Ligand-Target Pair
Complement factor B


(Homo sapiens (Human))
BDBM160506
PNG
(US10093663, Example 40 | US9682968, Example-40)
Show SMILES CC(=O)NS(=O)(=O)c1ccc(cc1)C1CCCCN1Cc1c(cc(C)c2[nH]ccc12)C1CC1
PDB

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Novartis AG

US Patent


Assay Description
CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...


US Patent US9682968 (2017)


BindingDB Entry DOI: 10.7270/Q2XG9P9J
More data for this
Ligand-Target Pair
Complement factor B


(Homo sapiens (Human))
BDBM159379
PNG
(US10093663, Example 17-8 | US9682968, Example-17-8)
Show SMILES COc1cc(C)c2[nH]ccc2c1CN1CCCC[C@H]1c1ccc(cc1F)C(O)=O |r|
PDB

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Novartis AG

US Patent


Assay Description
CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...


US Patent US9682968 (2017)


BindingDB Entry DOI: 10.7270/Q2XG9P9J
More data for this
Ligand-Target Pair
Complement factor B


(Homo sapiens (Human))
BDBM159316
PNG
(US9682968, Example-17-4)
Show SMILES COc1cc(ccc1[C@@H]1CCCCN1Cc1c(cc(C)c2[nH]ccc12)C1CC1)C(O)=O |r|
PDB

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Novartis AG

US Patent


Assay Description
CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...


US Patent US9682968 (2017)


BindingDB Entry DOI: 10.7270/Q2XG9P9J
More data for this
Ligand-Target Pair
Complement factor B


(Homo sapiens (Human))
BDBM159841
PNG
(US10093663, Example 17-22 | US9682968, Example-17-...)
Show SMILES COc1cc(C)c2[nH]ccc2c1CN1CCCCCC1c1ccc(cc1)C(O)=O
PDB

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Novartis AG

US Patent


Assay Description
CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...


US Patent US9682968 (2017)


BindingDB Entry DOI: 10.7270/Q2XG9P9J
More data for this
Ligand-Target Pair
Complement factor B


(Homo sapiens (Human))
BDBM159382
PNG
(US10093663, Example 17-10 | US9682968, Example-17-...)
Show SMILES COc1cc(C)c2[nH]ccc2c1CN1CCCC[C@H]1c1ccc(cn1)C(O)=O |r|
PDB

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Novartis AG

US Patent


Assay Description
CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...


US Patent US9682968 (2017)


BindingDB Entry DOI: 10.7270/Q2XG9P9J
More data for this
Ligand-Target Pair
Complement factor B


(Homo sapiens (Human))
BDBM159313
PNG
(US9682968, Example-17-2)
Show SMILES Cc1cc(C2CC2)c(CN2CCCC2c2ccc(cc2)C(O)=O)c2cc[nH]c12
PDB

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n/an/a 0.120n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...


US Patent US9682968 (2017)


BindingDB Entry DOI: 10.7270/Q2XG9P9J
More data for this
Ligand-Target Pair
Complement factor B


(Homo sapiens (Human))
BDBM160501
PNG
(US10093663, Example 38 | US9682968, Example-38)
Show SMILES CNC(=O)c1ccc(cc1)[C@@H]1C[C@H](CCN1Cc1c(OC)cc(C)c2[nH]ccc12)OC |r|
PDB

UniProtKB/SwissProt

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UniChem
US Patent
n/an/a 0.130n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...


US Patent US9682968 (2017)


BindingDB Entry DOI: 10.7270/Q2XG9P9J
More data for this
Ligand-Target Pair
Complement factor B


(Homo sapiens (Human))
BDBM159303
PNG
(US10093663, Example 13 | US9682968, Example-13)
Show SMILES Cc1cc(Cl)c(CN2CCCCC2c2ccc(cc2)C(O)=O)c2cc[nH]c12
PDB

UniProtKB/SwissProt

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UniChem
US Patent
n/an/a 0.140n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...


US Patent US9682968 (2017)


BindingDB Entry DOI: 10.7270/Q2XG9P9J
More data for this
Ligand-Target Pair
Complement factor B


(Homo sapiens (Human))
BDBM159932
PNG
(US10093663, Example 17-28 | US9682968, Example-17-...)
Show SMILES COc1cc(C)c2[nH]ccc2c1CN1CCCCC1c1ccc(C(O)=O)c(OC)c1
PDB

UniProtKB/SwissProt

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UniChem
US Patent
n/an/a 0.160n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...


US Patent US9682968 (2017)


BindingDB Entry DOI: 10.7270/Q2XG9P9J
More data for this
Ligand-Target Pair
Complement factor B


(Homo sapiens (Human))
BDBM160507
PNG
(US9682968, Example-41)
Show SMILES CCNC(=O)c1ccc(cc1)[C@@H]1C[C@H](C)CCN1Cc1c(OC)cc(C)c2[nH]ccc12 |r|
PDB

UniProtKB/SwissProt

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UniChem
US Patent
n/an/a 0.170n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...


US Patent US9682968 (2017)


BindingDB Entry DOI: 10.7270/Q2XG9P9J
More data for this
Ligand-Target Pair
Complement factor B


(Homo sapiens (Human))
BDBM159157
PNG
(US10093663, Example 5-4 | US9682968, Example-5-4)
Show SMILES Cc1cc(C)c2[nH]ccc2c1CN1CCCCC1c1ccc(cc1)S(N)(=O)=O
PDB

UniProtKB/SwissProt

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UniChem
US Patent
n/an/a 0.180n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...


US Patent US9682968 (2017)


BindingDB Entry DOI: 10.7270/Q2XG9P9J
More data for this
Ligand-Target Pair
Complement factor B


(Homo sapiens (Human))
BDBM159301
PNG
(US9682968, Example-11)
Show SMILES Cc1cc(C)c2[nH]ccc2c1CN1CCC(O)CC1c1ccc(cc1)C(N)=O
PDB

UniProtKB/SwissProt

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UniChem
US Patent
n/an/a 0.230n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...


US Patent US9682968 (2017)


BindingDB Entry DOI: 10.7270/Q2XG9P9J
More data for this
Ligand-Target Pair
Complement factor B


(Homo sapiens (Human))
BDBM160508
PNG
(US10093663, Example 42 | US9682968, Example-42)
Show SMILES CCO[C@H]1CCN(Cc2c(OC)cc(C)c3[nH]ccc23)[C@@H](C1)c1ccc(cc1)C(=O)OCC |r|
PDB

UniProtKB/SwissProt

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UniChem
US Patent
n/an/a 0.240n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...


US Patent US9682968 (2017)


BindingDB Entry DOI: 10.7270/Q2XG9P9J
More data for this
Ligand-Target Pair
Complement factor B


(Homo sapiens (Human))
BDBM160504
PNG
(US10093663, Example 39-3 | US9682968, Example-39-3)
Show SMILES CO[C@H]1CCN(Cc2c(OC)cc(C)c3[nH]ccc23)[C@@H](C1)c1ccc(cc1)C(=O)NCCO |r|
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/a 0.280n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...


US Patent US9682968 (2017)


BindingDB Entry DOI: 10.7270/Q2XG9P9J
More data for this
Ligand-Target Pair
Complement factor B


(Homo sapiens (Human))
BDBM159976
PNG
(US10093663, Example 20b | US9682968, Example-20b)
Show SMILES COc1cc(C)c2[nH]ccc2c1CN1CC[C@H](C)C[C@@H]1c1ccc(cc1)C(O)=O |r|
PDB

UniProtKB/SwissProt

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US Patent
n/an/a 0.290n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...


US Patent US9682968 (2017)


BindingDB Entry DOI: 10.7270/Q2XG9P9J
More data for this
Ligand-Target Pair
Complement factor B


(Homo sapiens (Human))
BDBM160505
PNG
(US10093663, Example 39-4 | US9682968, Example-39-4)
Show SMILES COCCNC(=O)c1ccc(cc1)[C@@H]1C[C@H](CCN1Cc1c(OC)cc(C)c2[nH]ccc12)OC |r|
PDB

UniProtKB/SwissProt

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UniChem
US Patent
n/an/a 0.300n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...


US Patent US9682968 (2017)


BindingDB Entry DOI: 10.7270/Q2XG9P9J
More data for this
Ligand-Target Pair
Complement factor B


(Homo sapiens (Human))
BDBM160495
PNG
(US10093663, Example 32-3 | US9682968, Example-32-3)
Show SMILES COC1CCN(Cc2c(OC)cc(C)c3[nH]ccc23)C(C1)c1ccc(CO)cc1
PDB

UniProtKB/SwissProt

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UniChem
US Patent
n/an/a 0.340n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...


US Patent US9682968 (2017)


BindingDB Entry DOI: 10.7270/Q2XG9P9J
More data for this
Ligand-Target Pair
Complement factor B


(Homo sapiens (Human))
BDBM159506
PNG
(US10093663, Example 17-12 | US9682968, Example-17-...)
Show SMILES COc1cc(C)c2[nH]ccc2c1CN1CC[C@H](O)C[C@H]1c1ccc(cc1)C(O)=O |r|
PDB

UniProtKB/SwissProt

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UniChem
US Patent
n/an/a 0.450n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...


US Patent US9682968 (2017)


BindingDB Entry DOI: 10.7270/Q2XG9P9J
More data for this
Ligand-Target Pair
Complement factor B


(Homo sapiens (Human))
BDBM159296
PNG
(US10093663, Example 9-2 | US9682968, Example-9-2)
Show SMILES COC1CCN(Cc2c(C)cc(C)c3[nH]ccc23)C(C1)c1ccc(cc1)C(N)=O
PDB

UniProtKB/SwissProt

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US Patent
n/an/a 0.640n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...


US Patent US9682968 (2017)


BindingDB Entry DOI: 10.7270/Q2XG9P9J
More data for this
Ligand-Target Pair
Complement factor B


(Homo sapiens (Human))
BDBM160051
PNG
(US10093663, Example 21b | US9682968, Example-21b)
Show SMILES CO[C@@H]1CCN(Cc2c(OC)cc(C)c3[nH]ccc23)[C@H](C1)c1ccc(cc1)C(O)=O |r|
PDB

UniProtKB/SwissProt

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UniChem
US Patent
n/an/a 0.650n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...


US Patent US9682968 (2017)


BindingDB Entry DOI: 10.7270/Q2XG9P9J
More data for this
Ligand-Target Pair
Complement factor B


(Homo sapiens (Human))
BDBM159184
PNG
(US10093663, Example 5-6 | US9682968, Example-5-6)
Show SMILES CNS(=O)(=O)c1ccc(cc1)C1CCCCN1Cc1c(C)cc(C)c2[nH]ccc12
PDB

UniProtKB/SwissProt

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US Patent
n/an/a 0.660n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...


US Patent US9682968 (2017)


BindingDB Entry DOI: 10.7270/Q2XG9P9J
More data for this
Ligand-Target Pair
Complement factor B


(Homo sapiens (Human))
BDBM159294
PNG
(US10093663, Example 8 | US9682968, Example-8)
Show SMILES Cc1cc(C)c2[nH]ccc2c1CN1CCCCC1c1ccc(cc1)C(N)=O
PDB

UniProtKB/SwissProt

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UniChem
US Patent
n/an/a 0.710n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...


US Patent US9682968 (2017)


BindingDB Entry DOI: 10.7270/Q2XG9P9J
More data for this
Ligand-Target Pair
Complement factor B


(Homo sapiens (Human))
BDBM159114
PNG
(US9682968, Example-4b (-))
Show SMILES COC1CCN(Cc2c(C)cc(C)c3[nH]ccc23)C(C1)c1ccccc1
PDB

UniProtKB/SwissProt

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US Patent
n/an/a 0.720n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...


US Patent US9682968 (2017)


BindingDB Entry DOI: 10.7270/Q2XG9P9J
More data for this
Ligand-Target Pair
Complement factor B


(Homo sapiens (Human))
BDBM160484
PNG
(US9682968, Example-27-3b (+))
Show SMILES COC1CCN(Cc2c(cc(C)c3[nH]ccc23)C2CC2)C(C1)c1ccc(cc1)C(O)=O
PDB

UniProtKB/SwissProt

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UniChem
US Patent
n/an/a 0.740n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...


US Patent US9682968 (2017)


BindingDB Entry DOI: 10.7270/Q2XG9P9J
More data for this
Ligand-Target Pair
Complement factor B


(Homo sapiens (Human))
BDBM159840
PNG
(US10093663, Example 17-21 | US9682968, Example-17-...)
Show SMILES Cc1cc(C)c2[nH]ccc2c1CN1CCCCC1c1cccc(c1)C(O)=O
PDB

UniProtKB/SwissProt

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PC sid
UniChem
US Patent
n/an/a 0.840n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...


US Patent US9682968 (2017)


BindingDB Entry DOI: 10.7270/Q2XG9P9J
More data for this
Ligand-Target Pair
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