Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
D-amino-acid oxidase (Homo sapiens (Human)) | BDBM50433372 (CHEMBL2375520) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals Inc. Curated by ChEMBL | Assay Description Competitive inhibition of human recombinant DAAO by Michaelis-Menten plot analysis in presence of D-serine | J Med Chem 56: 3710-24 (2013) Article DOI: 10.1021/jm4002583 BindingDB Entry DOI: 10.7270/Q2X92CPC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-amino-acid oxidase (Homo sapiens (Human)) | BDBM50260725 (4H-thieno[3,2-b]pyrrole-5-carboxylic acid | CHEMBL...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents | PDB Article PubMed | 3.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals Inc. Curated by ChEMBL | Assay Description Competitive inhibition of human recombinant DAAO by Michaelis-Menten plot analysis in presence of D-serine | J Med Chem 56: 3710-24 (2013) Article DOI: 10.1021/jm4002583 BindingDB Entry DOI: 10.7270/Q2X92CPC | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
D-amino-acid oxidase (Homo sapiens (Human)) | BDBM50260722 (4-(4-chlorophenethyl)-1H-pyrrole-2-carboxylic acid...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Patents | PDB Article PubMed | 7.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals Inc. Curated by ChEMBL | Assay Description Competitive inhibition of human recombinant DAAO by Michaelis-Menten plot analysis in presence of D-serine | J Med Chem 56: 3710-24 (2013) Article DOI: 10.1021/jm4002583 BindingDB Entry DOI: 10.7270/Q2X92CPC | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Amiloride-sensitive amine oxidase [copper-containing] (Homo sapiens (Human)) | BDBM50000999 (CHEBI:81724 | DIMINAZENE) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase DrugBank MCE KEGG PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Xavier University of Louisiana Curated by ChEMBL | Assay Description Mixed type inhibition of recombinant human DAO expressed in drosophila S2 cells | Bioorg Med Chem 22: 1983-92 (2014) Article DOI: 10.1016/j.bmc.2014.02.049 BindingDB Entry DOI: 10.7270/Q2N29ZGG | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
D-amino-acid oxidase (Homo sapiens (Human)) | BDBM50206007 (3-Hydroxy-chromen-2-one | 3-hydroxy-2H-chromen-2-o...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals Inc. Curated by ChEMBL | Assay Description Competitive inhibition of human recombinant DAAO by Michaelis-Menten plot analysis in presence of D-serine | J Med Chem 56: 3710-24 (2013) Article DOI: 10.1021/jm4002583 BindingDB Entry DOI: 10.7270/Q2X92CPC | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
D-amino-acid oxidase (Homo sapiens (Human)) | BDBM31147 (4H-furo[3,2-b]pyrrole-5-carboxylic acid | 5-carbox...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents | MMDB PDB Article PubMed | 36 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University Curated by ChEMBL | Assay Description Inhibition of human recombinant N-terminal His-tagged DAO expressed in Escherichia coli BL21(DE3) using D-serine as substrate by Lineweaver-Burk plot... | J Med Chem 56: 1894-907 (2013) Article DOI: 10.1021/jm3017865 BindingDB Entry DOI: 10.7270/Q2H70H4P | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
D-amino-acid oxidase (Homo sapiens (Human)) | BDBM50117763 (CHEMBL3613921 | US9505753, 5u) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johns Hopkins University Curated by ChEMBL | Assay Description Competitive inhibition of recombinant human DAAO expressed in HEK cells by double reciprocal plot analysis in presence of D-serine | J Med Chem 58: 7258-72 (2015) Article DOI: 10.1021/acs.jmedchem.5b00482 BindingDB Entry DOI: 10.7270/Q2SF2XZQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amiloride-sensitive amine oxidase [copper-containing] (Homo sapiens (Human)) | BDBM50207159 (2-aminoguanidine | 2-azanylguanidine | AMINOGUANID...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents | Article | 140 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Tested for ability of the compound to competitively inhibit hog kidney diamine oxidase (DAO) in a spectrometric assay | Bioorg Med Chem Lett 3: 353-356 (1993) Article DOI: 10.1016/S0960-894X(01)80909-4 BindingDB Entry DOI: 10.7270/Q24749ST | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-amino-acid oxidase (Homo sapiens (Human)) | BDBM50206007 (3-Hydroxy-chromen-2-one | 3-hydroxy-2H-chromen-2-o...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 156 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University Curated by ChEMBL | Assay Description Inhibition of human recombinant N-terminal His-tagged DAO expressed in Escherichia coli BL21(DE3) using D-serine as substrate by Lineweaver-Burk plot... | J Med Chem 56: 1894-907 (2013) Article DOI: 10.1021/jm3017865 BindingDB Entry DOI: 10.7270/Q2H70H4P | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Amiloride-sensitive amine oxidase [copper-containing] (Homo sapiens (Human)) | BDBM50281515 ((E)-3-(1H-Imidazol-4-yl)-allylamine | CHEMBL119195...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article | 170 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Tested for ability of the compound to competitively inhibit hog kidney diamine oxidase (DAO) in a spectrometric assay | Bioorg Med Chem Lett 3: 353-356 (1993) Article DOI: 10.1016/S0960-894X(01)80909-4 BindingDB Entry DOI: 10.7270/Q24749ST | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-amino-acid oxidase (Homo sapiens (Human)) | BDBM50433371 (CHEMBL2375519) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid UniChem | Article PubMed | 190 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals Inc. Curated by ChEMBL | Assay Description Competitive inhibition of human recombinant DAAO by Michaelis-Menten plot analysis in presence of D-serine | J Med Chem 56: 3710-24 (2013) Article DOI: 10.1021/jm4002583 BindingDB Entry DOI: 10.7270/Q2X92CPC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amiloride-sensitive amine oxidase [copper-containing] (Homo sapiens (Human)) | BDBM50281515 ((E)-3-(1H-Imidazol-4-yl)-allylamine | CHEMBL119195...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article | 200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Tested for ability of the compound to competitively inhibit hog kidney diamine oxidase (DAO) in a spectrometric assay | Bioorg Med Chem Lett 3: 353-356 (1993) Article DOI: 10.1016/S0960-894X(01)80909-4 BindingDB Entry DOI: 10.7270/Q24749ST | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amiloride-sensitive amine oxidase [copper-containing] (Homo sapiens (Human)) | BDBM45440 (4-[5-(4-amidinophenoxy)pentoxy]benzamidine;2-hydro...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 290 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Xavier University of Louisiana Curated by ChEMBL | Assay Description Mixed type inhibition of recombinant human DAO expressed in drosophila S2 cells | Bioorg Med Chem 22: 1983-92 (2014) Article DOI: 10.1016/j.bmc.2014.02.049 BindingDB Entry DOI: 10.7270/Q2N29ZGG | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Amiloride-sensitive amine oxidase [copper-containing] (Homo sapiens (Human)) | BDBM50281517 (3-(1H-Imidazol-4-yl)-prop-2-ynylamine | CHEMBL1165...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Tested for ability of the compound to competitively inhibit hog kidney diamine oxidase (DAO) in a spectrometric assay | Bioorg Med Chem Lett 3: 353-356 (1993) Article DOI: 10.1016/S0960-894X(01)80909-4 BindingDB Entry DOI: 10.7270/Q24749ST | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-amino-acid oxidase (Homo sapiens (Human)) | BDBM36181 (SODIUM BENZOATE | benzoate | benzoic acid | benzoi...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals Inc. Curated by ChEMBL | Assay Description Competitive inhibition of human recombinant DAAO by Michaelis-Menten plot analysis in presence of D-serine | J Med Chem 56: 3710-24 (2013) Article DOI: 10.1021/jm4002583 BindingDB Entry DOI: 10.7270/Q2X92CPC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amiloride-sensitive amine oxidase [copper-containing] (Homo sapiens (Human)) | BDBM50020274 (2,2-Difluoro-hex-5-yne-1,4-diamonium; dichloride |...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | 2.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merrell Dow Research Institute Curated by ChEMBL | Assay Description In vitro inhibition against hog kidney diamine oxidase | J Med Chem 32: 170-3 (1989) BindingDB Entry DOI: 10.7270/Q2DB80TK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-amino-acid oxidase (Sus scrofa (pig)) | BDBM50004955 (1H-Indole-2-carboxylic acid | CHEMBL278390 | Indol...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 3.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals Inc. Curated by ChEMBL | Assay Description Competitive inhibition of pig kidney DAAO in presence of D-alanine | J Med Chem 56: 3710-24 (2013) Article DOI: 10.1021/jm4002583 BindingDB Entry DOI: 10.7270/Q2X92CPC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amiloride-sensitive amine oxidase [copper-containing] (Homo sapiens (Human)) | BDBM50121458 (1-[3-(2-Hydroxy-phenyl)-5-o-tolyl-4,5-dihydro-pyra...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | 5.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Roma La Sapienza Curated by ChEMBL | Assay Description Inhibitory activity of the compound against Swine kidney diamine oxidase (SKDAO) | Bioorg Med Chem Lett 12: 3629-33 (2002) BindingDB Entry DOI: 10.7270/Q22B8XD8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-amino-acid oxidase (Homo sapiens (Human)) | BDBM36181 (SODIUM BENZOATE | benzoate | benzoic acid | benzoi...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | 7.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University Curated by ChEMBL | Assay Description Inhibition of human recombinant DAO expressed in Escherichia coli BL21(DE3) by oxygraphic assay | J Med Chem 56: 1894-907 (2013) Article DOI: 10.1021/jm3017865 BindingDB Entry DOI: 10.7270/Q2H70H4P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amiloride-sensitive amine oxidase [copper-containing] (Homo sapiens (Human)) | BDBM50281518 (2-(1H-Imidazol-4-yl)-allylamine | CHEMBL116538) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem | Article | 7.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Tested for ability of the compound to competitively inhibit hog kidney diamine oxidase (DAO) in a spectrometric assay | Bioorg Med Chem Lett 3: 353-356 (1993) Article DOI: 10.1016/S0960-894X(01)80909-4 BindingDB Entry DOI: 10.7270/Q24749ST | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amiloride-sensitive amine oxidase [copper-containing] (Homo sapiens (Human)) | BDBM50121455 (1-[3-(2-Hydroxy-phenyl)-5-m-tolyl-4,5-dihydro-pyra...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | 8.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Roma La Sapienza Curated by ChEMBL | Assay Description Inhibitory activity of the compound against Swine kidney diamine oxidase (SKDAO) | Bioorg Med Chem Lett 12: 3629-33 (2002) BindingDB Entry DOI: 10.7270/Q22B8XD8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-amino-acid oxidase (Homo sapiens (Human)) | BDBM50074328 (CHEMBL164585 | Thiophene-3-carboxylic acid) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents | Article PubMed | 8.16E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University Curated by ChEMBL | Assay Description Inhibition of human recombinant N-terminal His-tagged DAO expressed in Escherichia coli BL21(DE3) using D-serine as substrate by Lineweaver-Burk plot... | J Med Chem 56: 1894-907 (2013) Article DOI: 10.1021/jm3017865 BindingDB Entry DOI: 10.7270/Q2H70H4P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-amino-acid oxidase (Homo sapiens (Human)) | BDBM50427206 (CHEMBL2324852) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | 9.92E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University Curated by ChEMBL | Assay Description Inhibition of human recombinant N-terminal His-tagged DAO expressed in Escherichia coli BL21(DE3) using D-serine as substrate by Lineweaver-Burk plot... | J Med Chem 56: 1894-907 (2013) Article DOI: 10.1021/jm3017865 BindingDB Entry DOI: 10.7270/Q2H70H4P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-amino-acid oxidase (Homo sapiens (Human)) | BDBM36181 (SODIUM BENZOATE | benzoate | benzoic acid | benzoi...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | 1.09E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University Curated by ChEMBL | Assay Description Inhibition of human recombinant N-terminal His-tagged DAO expressed in Escherichia coli BL21(DE3) using D-serine as substrate by Lineweaver-Burk plot... | J Med Chem 56: 1894-907 (2013) Article DOI: 10.1021/jm3017865 BindingDB Entry DOI: 10.7270/Q2H70H4P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D-amino-acid oxidase (Sus scrofa (pig)) | BDBM50031467 (5-HYDROXY-2-(HYDROXYMETHYL)-4H-PYRAN-4-ONE | 5-Hyd...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 2.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johns Hopkins University Curated by ChEMBL | Assay Description Competitive inhibition of pig kidney DAAO using D-Alanine as substrate by Michaelis-Menten plot analysis | Bioorg Med Chem Lett 23: 3910-3 (2013) Article DOI: 10.1016/j.bmcl.2013.04.062 BindingDB Entry DOI: 10.7270/Q2K35W2G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amiloride-sensitive amine oxidase [copper-containing] (Homo sapiens (Human)) | BDBM50121457 (1-[3-(2,4-Dihydroxy-phenyl)-5-m-tolyl-4,5-dihydro-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Roma La Sapienza Curated by ChEMBL | Assay Description Inhibitory activity of the compound against Swine kidney diamine oxidase (SKDAO) | Bioorg Med Chem Lett 12: 3629-33 (2002) BindingDB Entry DOI: 10.7270/Q22B8XD8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amiloride-sensitive amine oxidase [copper-containing] (Homo sapiens (Human)) | BDBM50121456 (1-[3-(2,4-Dihydroxy-phenyl)-5-o-tolyl-4,5-dihydro-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Roma La Sapienza Curated by ChEMBL | Assay Description Inhibitory activity of the compound against Swine kidney diamine oxidase (SKDAO) | Bioorg Med Chem Lett 12: 3629-33 (2002) BindingDB Entry DOI: 10.7270/Q22B8XD8 | |||||||||||
More data for this Ligand-Target Pair |