Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM31094 (PKC-412 | cid_24202429) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 9.50E+5 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2542M0R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM31096 (CHEMBL290084 | Staurosporine | cid_451705) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 2.00E+4 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2542M0R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM108426 (US8609688, 4) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | 0.400 | n/a | n/a | n/a | 7.5 | 80 |
ArQule, Inc. US Patent | Assay Description Protein-ligand binding was identified with the thermal shift assay which is based on the ligand-induced stabilization of the protein tertiary structu... | US Patent US8609688 (2013) BindingDB Entry DOI: 10.7270/Q2H41Q2M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM108427 (US8609688, 5) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | 0.700 | n/a | n/a | n/a | 7.5 | 80 |
ArQule, Inc. US Patent | Assay Description Protein-ligand binding was identified with the thermal shift assay which is based on the ligand-induced stabilization of the protein tertiary structu... | US Patent US8609688 (2013) BindingDB Entry DOI: 10.7270/Q2H41Q2M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM108428 (US8609688, 6) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | 1.40 | n/a | n/a | n/a | 7.5 | 80 |
ArQule, Inc. US Patent | Assay Description Protein-ligand binding was identified with the thermal shift assay which is based on the ligand-induced stabilization of the protein tertiary structu... | US Patent US8609688 (2013) BindingDB Entry DOI: 10.7270/Q2H41Q2M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM108429 (US8609688, 7) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | 7.10 | n/a | n/a | n/a | 7.5 | 80 |
ArQule, Inc. US Patent | Assay Description Protein-ligand binding was identified with the thermal shift assay which is based on the ligand-induced stabilization of the protein tertiary structu... | US Patent US8609688 (2013) BindingDB Entry DOI: 10.7270/Q2H41Q2M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM108430 (US8609688, 8) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | 1.20 | n/a | n/a | n/a | 7.5 | 80 |
ArQule, Inc. US Patent | Assay Description Protein-ligand binding was identified with the thermal shift assay which is based on the ligand-induced stabilization of the protein tertiary structu... | US Patent US8609688 (2013) BindingDB Entry DOI: 10.7270/Q2H41Q2M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM108431 (US8609688, 9) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | 0.200 | n/a | n/a | n/a | 7.5 | 80 |
ArQule, Inc. US Patent | Assay Description Protein-ligand binding was identified with the thermal shift assay which is based on the ligand-induced stabilization of the protein tertiary structu... | US Patent US8609688 (2013) BindingDB Entry DOI: 10.7270/Q2H41Q2M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM108432 (US8609688, 10) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | 0.200 | n/a | n/a | n/a | 7.5 | 80 |
ArQule, Inc. US Patent | Assay Description Protein-ligand binding was identified with the thermal shift assay which is based on the ligand-induced stabilization of the protein tertiary structu... | US Patent US8609688 (2013) BindingDB Entry DOI: 10.7270/Q2H41Q2M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM108433 (US8609688, 11) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | 0.200 | n/a | n/a | n/a | 7.5 | 80 |
ArQule, Inc. US Patent | Assay Description Protein-ligand binding was identified with the thermal shift assay which is based on the ligand-induced stabilization of the protein tertiary structu... | US Patent US8609688 (2013) BindingDB Entry DOI: 10.7270/Q2H41Q2M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM108434 (US8609688, 12) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | 0.200 | n/a | n/a | n/a | 7.5 | 80 |
ArQule, Inc. US Patent | Assay Description Protein-ligand binding was identified with the thermal shift assay which is based on the ligand-induced stabilization of the protein tertiary structu... | US Patent US8609688 (2013) BindingDB Entry DOI: 10.7270/Q2H41Q2M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM108435 (US8609688, 13) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | 1.40 | n/a | n/a | n/a | 7.5 | 80 |
ArQule, Inc. US Patent | Assay Description Protein-ligand binding was identified with the thermal shift assay which is based on the ligand-induced stabilization of the protein tertiary structu... | US Patent US8609688 (2013) BindingDB Entry DOI: 10.7270/Q2H41Q2M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM108436 (US8609688, 14) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | 1.10 | n/a | n/a | n/a | 7.5 | 80 |
ArQule, Inc. US Patent | Assay Description Protein-ligand binding was identified with the thermal shift assay which is based on the ligand-induced stabilization of the protein tertiary structu... | US Patent US8609688 (2013) BindingDB Entry DOI: 10.7270/Q2H41Q2M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM108437 (US8609688, 15) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | 1.10 | n/a | n/a | n/a | 7.5 | 80 |
ArQule, Inc. US Patent | Assay Description Protein-ligand binding was identified with the thermal shift assay which is based on the ligand-induced stabilization of the protein tertiary structu... | US Patent US8609688 (2013) BindingDB Entry DOI: 10.7270/Q2H41Q2M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM108438 (US8609688, 16) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | 1.70 | n/a | n/a | n/a | 7.5 | 80 |
ArQule, Inc. US Patent | Assay Description Protein-ligand binding was identified with the thermal shift assay which is based on the ligand-induced stabilization of the protein tertiary structu... | US Patent US8609688 (2013) BindingDB Entry DOI: 10.7270/Q2H41Q2M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM108439 (US8609688, 17) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | 3.10 | n/a | n/a | n/a | 7.5 | 80 |
ArQule, Inc. US Patent | Assay Description Protein-ligand binding was identified with the thermal shift assay which is based on the ligand-induced stabilization of the protein tertiary structu... | US Patent US8609688 (2013) BindingDB Entry DOI: 10.7270/Q2H41Q2M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM108440 (US8609688, 18) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | 0.800 | n/a | n/a | n/a | 7.5 | 80 |
ArQule, Inc. US Patent | Assay Description Protein-ligand binding was identified with the thermal shift assay which is based on the ligand-induced stabilization of the protein tertiary structu... | US Patent US8609688 (2013) BindingDB Entry DOI: 10.7270/Q2H41Q2M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM108442 (US8609688, 20) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | 57.3 | n/a | n/a | n/a | 7.5 | 80 |
ArQule, Inc. US Patent | Assay Description AKT1 activity was assayed using the GSK3-derived biotinylated peptide substrate, crosstide (biotin-GRPRTSSFAEG), and AlphaScreen (Amplified Lum... | US Patent US8609688 (2013) BindingDB Entry DOI: 10.7270/Q2H41Q2M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM108443 (US8609688, 21) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 110 | n/a | n/a | n/a | 7.5 | 80 |
ArQule, Inc. US Patent | Assay Description Protein-ligand binding was identified with the thermal shift assay which is based on the ligand-induced stabilization of the protein tertiary structu... | US Patent US8609688 (2013) BindingDB Entry DOI: 10.7270/Q2H41Q2M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM108444 (US8609688, 22) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 83.1 | n/a | n/a | n/a | 7.5 | 80 |
ArQule, Inc. US Patent | Assay Description Protein-ligand binding was identified with the thermal shift assay which is based on the ligand-induced stabilization of the protein tertiary structu... | US Patent US8609688 (2013) BindingDB Entry DOI: 10.7270/Q2H41Q2M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM108425 (US8609688, 3) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | 7 | n/a | n/a | n/a | 7.5 | 80 |
ArQule, Inc. US Patent | Assay Description Protein-ligand binding was identified with the thermal shift assay which is based on the ligand-induced stabilization of the protein tertiary structu... | US Patent US8609688 (2013) BindingDB Entry DOI: 10.7270/Q2H41Q2M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM108425 (US8609688, 3) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a |
ArQule, Inc. US Patent | Assay Description Binding analysis. Protein-ligand binding was identified with the thermal shift assay which is based on the ligand-induced stabilization of the protei... | US Patent US8962619 (2015) BindingDB Entry DOI: 10.7270/Q2W957W7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM108426 (US8609688, 4) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | 0.400 | n/a | n/a | n/a | n/a | n/a |
ArQule, Inc. US Patent | Assay Description Binding analysis. Protein-ligand binding was identified with the thermal shift assay which is based on the ligand-induced stabilization of the protei... | US Patent US8962619 (2015) BindingDB Entry DOI: 10.7270/Q2W957W7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM108427 (US8609688, 5) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | 0.700 | n/a | n/a | n/a | n/a | n/a |
ArQule, Inc. US Patent | Assay Description Binding analysis. Protein-ligand binding was identified with the thermal shift assay which is based on the ligand-induced stabilization of the protei... | US Patent US8962619 (2015) BindingDB Entry DOI: 10.7270/Q2W957W7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM108428 (US8609688, 6) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a |
ArQule, Inc. US Patent | Assay Description Binding analysis. Protein-ligand binding was identified with the thermal shift assay which is based on the ligand-induced stabilization of the protei... | US Patent US8962619 (2015) BindingDB Entry DOI: 10.7270/Q2W957W7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM108429 (US8609688, 7) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | 7.10 | n/a | n/a | n/a | n/a | n/a |
ArQule, Inc. US Patent | Assay Description Binding analysis. Protein-ligand binding was identified with the thermal shift assay which is based on the ligand-induced stabilization of the protei... | US Patent US8962619 (2015) BindingDB Entry DOI: 10.7270/Q2W957W7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM108430 (US8609688, 8) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a |
ArQule, Inc. US Patent | Assay Description Binding analysis. Protein-ligand binding was identified with the thermal shift assay which is based on the ligand-induced stabilization of the protei... | US Patent US8962619 (2015) BindingDB Entry DOI: 10.7270/Q2W957W7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM108431 (US8609688, 9) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | n/a |
ArQule, Inc. US Patent | Assay Description Binding analysis. Protein-ligand binding was identified with the thermal shift assay which is based on the ligand-induced stabilization of the protei... | US Patent US8962619 (2015) BindingDB Entry DOI: 10.7270/Q2W957W7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM108432 (US8609688, 10) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | n/a |
ArQule, Inc. US Patent | Assay Description Binding analysis. Protein-ligand binding was identified with the thermal shift assay which is based on the ligand-induced stabilization of the protei... | US Patent US8962619 (2015) BindingDB Entry DOI: 10.7270/Q2W957W7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM108433 (US8609688, 11) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | n/a |
ArQule, Inc. US Patent | Assay Description Binding analysis. Protein-ligand binding was identified with the thermal shift assay which is based on the ligand-induced stabilization of the protei... | US Patent US8962619 (2015) BindingDB Entry DOI: 10.7270/Q2W957W7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM108434 (US8609688, 12) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | n/a |
ArQule, Inc. US Patent | Assay Description Binding analysis. Protein-ligand binding was identified with the thermal shift assay which is based on the ligand-induced stabilization of the protei... | US Patent US8962619 (2015) BindingDB Entry DOI: 10.7270/Q2W957W7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM108435 (US8609688, 13) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a |
ArQule, Inc. US Patent | Assay Description Binding analysis. Protein-ligand binding was identified with the thermal shift assay which is based on the ligand-induced stabilization of the protei... | US Patent US8962619 (2015) BindingDB Entry DOI: 10.7270/Q2W957W7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM108436 (US8609688, 14) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a |
ArQule, Inc. US Patent | Assay Description Binding analysis. Protein-ligand binding was identified with the thermal shift assay which is based on the ligand-induced stabilization of the protei... | US Patent US8962619 (2015) BindingDB Entry DOI: 10.7270/Q2W957W7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM108437 (US8609688, 15) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a |
ArQule, Inc. US Patent | Assay Description Binding analysis. Protein-ligand binding was identified with the thermal shift assay which is based on the ligand-induced stabilization of the protei... | US Patent US8962619 (2015) BindingDB Entry DOI: 10.7270/Q2W957W7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM108438 (US8609688, 16) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | 1.70 | n/a | n/a | n/a | n/a | n/a |
ArQule, Inc. US Patent | Assay Description Binding analysis. Protein-ligand binding was identified with the thermal shift assay which is based on the ligand-induced stabilization of the protei... | US Patent US8962619 (2015) BindingDB Entry DOI: 10.7270/Q2W957W7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM108439 (US8609688, 17) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | 3.10 | n/a | n/a | n/a | n/a | n/a |
ArQule, Inc. US Patent | Assay Description Binding analysis. Protein-ligand binding was identified with the thermal shift assay which is based on the ligand-induced stabilization of the protei... | US Patent US8962619 (2015) BindingDB Entry DOI: 10.7270/Q2W957W7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM108440 (US8609688, 18) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | 0.800 | n/a | n/a | n/a | n/a | n/a |
ArQule, Inc. US Patent | Assay Description Binding analysis. Protein-ligand binding was identified with the thermal shift assay which is based on the ligand-induced stabilization of the protei... | US Patent US8962619 (2015) BindingDB Entry DOI: 10.7270/Q2W957W7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM108442 (US8609688, 20) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | 57.3 | n/a | n/a | n/a | n/a | n/a |
ArQule, Inc. US Patent | Assay Description Binding analysis. Protein-ligand binding was identified with the thermal shift assay which is based on the ligand-induced stabilization of the protei... | US Patent US8962619 (2015) BindingDB Entry DOI: 10.7270/Q2W957W7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM108443 (US8609688, 21) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a |
ArQule, Inc. US Patent | Assay Description Binding analysis. Protein-ligand binding was identified with the thermal shift assay which is based on the ligand-induced stabilization of the protei... | US Patent US8962619 (2015) BindingDB Entry DOI: 10.7270/Q2W957W7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM108444 (US8609688, 22) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 83.1 | n/a | n/a | n/a | n/a | n/a |
ArQule, Inc. US Patent | Assay Description Binding analysis. Protein-ligand binding was identified with the thermal shift assay which is based on the ligand-induced stabilization of the protei... | US Patent US8962619 (2015) BindingDB Entry DOI: 10.7270/Q2W957W7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-alpha serine/threonine-protein kinase [E49C,C296S,C310S,C344S] (Homo sapiens (Human)) | BDBM153702 (2-(4-((4-(2-Oxo-2,3-dihydro-1H-benzo[d]imidazol-1-...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 410 | n/a | n/a | n/a | 7.4 | n/a |
Technische Universität Dortmund | Assay Description Labeled Akt1 was diluted to 200 nM in the measurement buffer consisting of 50 mMHEPES pH 7.4, 200 mM NaCl, and 0.01% Triton-X 100. Dilution series of... | ACS Chem Biol 10: 279-88 (2015) Article DOI: 10.1021/cb500355c BindingDB Entry DOI: 10.7270/Q218358G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-alpha serine/threonine-protein kinase [E49C,C296S,C310S,C344S] (Homo sapiens (Human)) | BDBM153703 (2-(4-((4-(5-Chloro-2-oxo-2,3-dihydro-1H-benzo[d]im...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 150 | n/a | n/a | n/a | 7.4 | n/a |
Technische Universität Dortmund | Assay Description Labeled Akt1 was diluted to 200 nM in the measurement buffer consisting of 50 mMHEPES pH 7.4, 200 mM NaCl, and 0.01% Triton-X 100. Dilution series of... | ACS Chem Biol 10: 279-88 (2015) Article DOI: 10.1021/cb500355c BindingDB Entry DOI: 10.7270/Q218358G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-alpha serine/threonine-protein kinase [E49C,C296S,C310S,C344S] (Homo sapiens (Human)) | BDBM153704 (2-(4-((3,4-Dihydroisoquinolin-2(1H)-yl)methyl)phen...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 6.00E+3 | n/a | n/a | n/a | 7.4 | n/a |
Technische Universität Dortmund | Assay Description Labeled Akt1 was diluted to 200 nM in the measurement buffer consisting of 50 mMHEPES pH 7.4, 200 mM NaCl, and 0.01% Triton-X 100. Dilution series of... | ACS Chem Biol 10: 279-88 (2015) Article DOI: 10.1021/cb500355c BindingDB Entry DOI: 10.7270/Q218358G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-alpha serine/threonine-protein kinase [E49C,C296S,C310S,C344S] (Homo sapiens (Human)) | BDBM153705 (Methyl 1-(4-(5-oxo-3-phenyl-5,6-dihydro-1,6-naphth...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 900 | n/a | n/a | n/a | 7.4 | n/a |
Technische Universität Dortmund | Assay Description Labeled Akt1 was diluted to 200 nM in the measurement buffer consisting of 50 mMHEPES pH 7.4, 200 mM NaCl, and 0.01% Triton-X 100. Dilution series of... | ACS Chem Biol 10: 279-88 (2015) Article DOI: 10.1021/cb500355c BindingDB Entry DOI: 10.7270/Q218358G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-alpha serine/threonine-protein kinase [E49C,C296S,C310S,C344S] (Homo sapiens (Human)) | BDBM153706 (2-(4-((4-(4-Methoxyphenyl)piperazin-1-yl)methyl)ph...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 7.20E+3 | n/a | n/a | n/a | 7.4 | n/a |
Technische Universität Dortmund | Assay Description Labeled Akt1 was diluted to 200 nM in the measurement buffer consisting of 50 mMHEPES pH 7.4, 200 mM NaCl, and 0.01% Triton-X 100. Dilution series of... | ACS Chem Biol 10: 279-88 (2015) Article DOI: 10.1021/cb500355c BindingDB Entry DOI: 10.7270/Q218358G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-alpha serine/threonine-protein kinase [E49C,C296S,C310S,C344S] (Homo sapiens (Human)) | BDBM153707 (3-Phenyl-2-(4-((4-(pyrimidin-2-yl)piperazin-1-yl)m...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 1.10E+3 | n/a | n/a | n/a | 7.4 | n/a |
Technische Universität Dortmund | Assay Description Labeled Akt1 was diluted to 200 nM in the measurement buffer consisting of 50 mMHEPES pH 7.4, 200 mM NaCl, and 0.01% Triton-X 100. Dilution series of... | ACS Chem Biol 10: 279-88 (2015) Article DOI: 10.1021/cb500355c BindingDB Entry DOI: 10.7270/Q218358G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-alpha serine/threonine-protein kinase [E49C,C296S,C310S,C344S] (Homo sapiens (Human)) | BDBM153708 (3-Phenyl-2-(4-((4-(tetrahydrofuran-2-carbonyl)pipe...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 8.00E+3 | n/a | n/a | n/a | 7.4 | n/a |
Technische Universität Dortmund | Assay Description Labeled Akt1 was diluted to 200 nM in the measurement buffer consisting of 50 mMHEPES pH 7.4, 200 mM NaCl, and 0.01% Triton-X 100. Dilution series of... | ACS Chem Biol 10: 279-88 (2015) Article DOI: 10.1021/cb500355c BindingDB Entry DOI: 10.7270/Q218358G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-alpha serine/threonine-protein kinase [E49C,C296S,C310S,C344S] (Homo sapiens (Human)) | BDBM50313650 (8-(4-(1-aminocyclobutyl)phenyl)-9-phenyl-[1,2,4]tr...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | n/a | 90 | n/a | n/a | n/a | 7.4 | n/a |
Technische Universität Dortmund | Assay Description Labeled Akt1 was diluted to 200 nM in the measurement buffer consisting of 50 mMHEPES pH 7.4, 200 mM NaCl, and 0.01% Triton-X 100. Dilution series of... | ACS Chem Biol 10: 279-88 (2015) Article DOI: 10.1021/cb500355c BindingDB Entry DOI: 10.7270/Q218358G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-alpha serine/threonine-protein kinase [E49C,C296S,C310S,C344S] (Homo sapiens (Human)) | BDBM153709 (7-(4-methylphenyl)-5-phenyl-N-(thiophen-2-ylmethyl...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 2.20E+3 | n/a | n/a | n/a | 7.4 | n/a |
Technische Universität Dortmund | Assay Description Labeled Akt1 was diluted to 200 nM in the measurement buffer consisting of 50 mMHEPES pH 7.4, 200 mM NaCl, and 0.01% Triton-X 100. Dilution series of... | ACS Chem Biol 10: 279-88 (2015) Article DOI: 10.1021/cb500355c BindingDB Entry DOI: 10.7270/Q218358G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-alpha serine/threonine-protein kinase [E49C,C296S,C310S,C344S] (Homo sapiens (Human)) | BDBM153710 (7-(4-methylphenyl)-5-phenyl-N-(pyridin-3-ylmethyl)...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 7.80E+3 | n/a | n/a | n/a | 7.4 | n/a |
Technische Universität Dortmund | Assay Description Labeled Akt1 was diluted to 200 nM in the measurement buffer consisting of 50 mMHEPES pH 7.4, 200 mM NaCl, and 0.01% Triton-X 100. Dilution series of... | ACS Chem Biol 10: 279-88 (2015) Article DOI: 10.1021/cb500355c BindingDB Entry DOI: 10.7270/Q218358G | |||||||||||
More data for this Ligand-Target Pair |
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