Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Polymerase acidic protein [1-204,T86I,G186S] (2009 H1N1 Influenza) | BDBM105203 (6-(4-Fluorophenyl)-3-hydroxy-5-[4-(1H-1, 2, 3, 4-t...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | MMDB PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Rutgers University | Assay Description Cocktails of 4-8 compounds were used for the initial screening with single compound soaks to verify the bound fragment identity and to rule out coope... | ACS Chem Biol 8: 2501-8 (2013) Article DOI: 10.1021/cb400400j BindingDB Entry DOI: 10.7270/Q28W3BZW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polymerase acidic protein [1-204,T86I,G186S] (2009 H1N1 Influenza) | BDBM105202 (5,6-bis(4-Fluorophenyl)-3-hydroxypyridin-2(1H)-one...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | MMDB PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 41 | n/a | n/a | n/a | n/a | n/a | n/a |
Rutgers University | Assay Description Cocktails of 4-8 compounds were used for the initial screening with single compound soaks to verify the bound fragment identity and to rule out coope... | ACS Chem Biol 8: 2501-8 (2013) Article DOI: 10.1021/cb400400j BindingDB Entry DOI: 10.7270/Q28W3BZW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polymerase acidic protein [1-204,T86I,G186S] (2009 H1N1 Influenza) | BDBM105200 (6-Phenyl-3-hydroxypyridin-2(1H)-one (Compound 4)) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | MMDB PC cid PC sid UniChem | Article PubMed | n/a | n/a | 380 | n/a | n/a | n/a | n/a | n/a | n/a |
Rutgers University | Assay Description Cocktails of 4-8 compounds were used for the initial screening with single compound soaks to verify the bound fragment identity and to rule out coope... | ACS Chem Biol 8: 2501-8 (2013) Article DOI: 10.1021/cb400400j BindingDB Entry DOI: 10.7270/Q28W3BZW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polymerase acidic protein [1-204,T86I,G186S] (2009 H1N1 Influenza) | BDBM105201 (6-(3-Methoxyphenyl-3-hydroxypyridin-2(1H)-one (Com...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | MMDB PC cid PC sid UniChem | Article PubMed | n/a | n/a | 450 | n/a | n/a | n/a | n/a | n/a | n/a |
Rutgers University | Assay Description Cocktails of 4-8 compounds were used for the initial screening with single compound soaks to verify the bound fragment identity and to rule out coope... | ACS Chem Biol 8: 2501-8 (2013) Article DOI: 10.1021/cb400400j BindingDB Entry DOI: 10.7270/Q28W3BZW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polymerase acidic protein [1-204,T86I,G186S] (2009 H1N1 Influenza) | BDBM105199 (5-(3-Cyanophenyl)-3-hydroxypyridin-2(1H)-one (Comp...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MMDB PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | 730 | n/a | n/a | n/a | n/a | n/a | n/a |
Rutgers University | Assay Description Cocktails of 4-8 compounds were used for the initial screening with single compound soaks to verify the bound fragment identity and to rule out coope... | ACS Chem Biol 8: 2501-8 (2013) Article DOI: 10.1021/cb400400j BindingDB Entry DOI: 10.7270/Q28W3BZW | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Polymerase acidic protein [1-204,T86I,G186S] (2009 H1N1 Influenza) | BDBM50291683 (1-(3,4-Dihydroxy-benzyl)-2-methyl-1,2,3,4-tetrahyd...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Rutgers University | ACS Chem Biol 8: 2501-8 (2013) Article DOI: 10.1021/cb400400j BindingDB Entry DOI: 10.7270/Q28W3BZW | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polymerase acidic protein [1-204,T86I,G186S] (2009 H1N1 Influenza) | BDBM50291683 (1-(3,4-Dihydroxy-benzyl)-2-methyl-1,2,3,4-tetrahyd...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Rutgers University | Assay Description Cocktails of 4-8 compounds were used for the initial screening with single compound soaks to verify the bound fragment identity and to rule out coope... | ACS Chem Biol 8: 2501-8 (2013) Article DOI: 10.1021/cb400400j BindingDB Entry DOI: 10.7270/Q28W3BZW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polymerase acidic protein [1-204,T86I,G186S] (2009 H1N1 Influenza) | BDBM105198 (5‐bromo‐3‐hydroxy‐1,2̴...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE MMDB PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | 1.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Rutgers University | Assay Description Cocktails of 4-8 compounds were used for the initial screening with single compound soaks to verify the bound fragment identity and to rule out coope... | ACS Chem Biol 8: 2501-8 (2013) Article DOI: 10.1021/cb400400j BindingDB Entry DOI: 10.7270/Q28W3BZW | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Polymerase acidic protein [1-204,T86I,G186S] (2009 H1N1 Influenza) | BDBM105189 (5-chloropyridine-2,3-diol (CV22-1) | CHEMBL2338783) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Rutgers University | ACS Chem Biol 8: 2501-8 (2013) Article DOI: 10.1021/cb400400j BindingDB Entry DOI: 10.7270/Q28W3BZW | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polymerase acidic protein [1-204,T86I,G186S] (2009 H1N1 Influenza) | BDBM105189 (5-chloropyridine-2,3-diol (CV22-1) | CHEMBL2338783) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Rutgers University | Assay Description Cocktails of 4-8 compounds were used for the initial screening with single compound soaks to verify the bound fragment identity and to rule out coope... | ACS Chem Biol 8: 2501-8 (2013) Article DOI: 10.1021/cb400400j BindingDB Entry DOI: 10.7270/Q28W3BZW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polymerase acidic protein [1-204,T86I,G186S] (2009 H1N1 Influenza) | BDBM50027331 (1-(3,4-dihydroxybenzyl)-1,2,3,4-tetrahydroisoquino...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Rutgers University | ACS Chem Biol 8: 2501-8 (2013) Article DOI: 10.1021/cb400400j BindingDB Entry DOI: 10.7270/Q28W3BZW | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polymerase acidic protein [1-204,T86I,G186S] (2009 H1N1 Influenza) | BDBM105188 (N-[3-(aminomethyl)phenyl]aminosulfonamide | N-[3-(...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.20E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Rutgers University | ACS Chem Biol 8: 2501-8 (2013) Article DOI: 10.1021/cb400400j BindingDB Entry DOI: 10.7270/Q28W3BZW | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polymerase acidic protein [1-204,T86I,G186S] (2009 H1N1 Influenza) | BDBM105194 (methyl 4-(methylsulfanyl)-6-oxo-2-phenyl-1,6-dihyd...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.50E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Rutgers University | Assay Description Cocktails of 4-8 compounds were used for the initial screening with single compound soaks to verify the bound fragment identity and to rule out coope... | ACS Chem Biol 8: 2501-8 (2013) Article DOI: 10.1021/cb400400j BindingDB Entry DOI: 10.7270/Q28W3BZW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polymerase acidic protein [1-204,T86I,G186S] (2009 H1N1 Influenza) | BDBM105184 (1-methyl-1H-1,3-benzodiazole-2-carboxylic acid (MB...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Rutgers University | ACS Chem Biol 8: 2501-8 (2013) Article DOI: 10.1021/cb400400j BindingDB Entry DOI: 10.7270/Q28W3BZW | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polymerase acidic protein [1-204,T86I,G186S] (2009 H1N1 Influenza) | BDBM105186 (isoquinoline-3-carboxylic acid (MB61-3)) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 3.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Rutgers University | ACS Chem Biol 8: 2501-8 (2013) Article DOI: 10.1021/cb400400j BindingDB Entry DOI: 10.7270/Q28W3BZW | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polymerase acidic protein [1-204,T86I,G186S] (2009 H1N1 Influenza) | BDBM105185 (7-aminothieno[2,3-b]pyrazine-6-carboxylic acid (MB...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Rutgers University | ACS Chem Biol 8: 2501-8 (2013) Article DOI: 10.1021/cb400400j BindingDB Entry DOI: 10.7270/Q28W3BZW | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polymerase acidic protein [1-204,T86I,G186S] (2009 H1N1 Influenza) | BDBM105187 ([4-(aminomethyl)phenyl]methanesulfonamide (EN-8)) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Rutgers University | ACS Chem Biol 8: 2501-8 (2013) Article DOI: 10.1021/cb400400j BindingDB Entry DOI: 10.7270/Q28W3BZW | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polymerase acidic protein [1-204,T86I,G186S] (2009 H1N1 Influenza) | BDBM105193 (4‐(1H‐imidazol‐1‐yl)phenol...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase DrugBank MCE PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Rutgers University | Assay Description Cocktails of 4-8 compounds were used for the initial screening with single compound soaks to verify the bound fragment identity and to rule out coope... | ACS Chem Biol 8: 2501-8 (2013) Article DOI: 10.1021/cb400400j BindingDB Entry DOI: 10.7270/Q28W3BZW | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Polymerase acidic protein [1-204,T86I,G186S] (2009 H1N1 Influenza) | BDBM105196 (3-bromoimidazo[1,2-a]pyridine) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Rutgers University | Assay Description Cocktails of 4-8 compounds were used for the initial screening with single compound soaks to verify the bound fragment identity and to rule out coope... | ACS Chem Biol 8: 2501-8 (2013) Article DOI: 10.1021/cb400400j BindingDB Entry DOI: 10.7270/Q28W3BZW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polymerase acidic protein [1-204,T86I,G186S] (2009 H1N1 Influenza) | BDBM105195 (6-bromopyridin-3-amine | EN300-53250) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Rutgers University | Assay Description Cocktails of 4-8 compounds were used for the initial screening with single compound soaks to verify the bound fragment identity and to rule out coope... | ACS Chem Biol 8: 2501-8 (2013) Article DOI: 10.1021/cb400400j BindingDB Entry DOI: 10.7270/Q28W3BZW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polymerase acidic protein [1-204,T86I,G186S] (2009 H1N1 Influenza) | BDBM105193 (4‐(1H‐imidazol‐1‐yl)phenol...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase DrugBank MCE PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Rutgers University | Assay Description Cocktails of 4-8 compounds were used for the initial screening with single compound soaks to verify the bound fragment identity and to rule out coope... | ACS Chem Biol 8: 2501-8 (2013) Article DOI: 10.1021/cb400400j BindingDB Entry DOI: 10.7270/Q28W3BZW | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Polymerase acidic protein [1-204,T86I,G186S] (2009 H1N1 Influenza) | BDBM105192 (3-Aminothieno[2,3-b]pyridine-2-carboxylic acid) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Rutgers University | Assay Description Cocktails of 4-8 compounds were used for the initial screening with single compound soaks to verify the bound fragment identity and to rule out coope... | ACS Chem Biol 8: 2501-8 (2013) Article DOI: 10.1021/cb400400j BindingDB Entry DOI: 10.7270/Q28W3BZW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polymerase acidic protein [1-204,T86I,G186S] (2009 H1N1 Influenza) | BDBM105191 (4-(1H-1,2,4-Triazol-1-yl)benzoic acid) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Rutgers University | Assay Description Cocktails of 4-8 compounds were used for the initial screening with single compound soaks to verify the bound fragment identity and to rule out coope... | ACS Chem Biol 8: 2501-8 (2013) Article DOI: 10.1021/cb400400j BindingDB Entry DOI: 10.7270/Q28W3BZW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polymerase acidic protein [1-204,T86I,G186S] (2009 H1N1 Influenza) | BDBM105190 (4-amino-3-bromopyridine | EN300-81773) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Rutgers University | Assay Description Cocktails of 4-8 compounds were used for the initial screening with single compound soaks to verify the bound fragment identity and to rule out coope... | ACS Chem Biol 8: 2501-8 (2013) Article DOI: 10.1021/cb400400j BindingDB Entry DOI: 10.7270/Q28W3BZW | |||||||||||
More data for this Ligand-Target Pair |