Compile Data Set for Download or QSAR

Found 54 hits Enz. Inhib. hit(s) with all data for entry = 2397   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Oxysterols receptor LXR-beta [154-461] (Homo sapiens (Human))	BDBM20024 (2-{4-[({3-[3-benzoyl-8-(trifluoromethyl)quinolin-4...) Show SMILES NC(=O)Cc1ccc(CNc2cccc(c2)-c2c(cnc3c(cccc23)C(F)(F)F)C(=O)c2ccccc2)cc1 Show InChI InChI=1S/C32H24F3N3O2/c33-32(34,35)27-11-5-10-25-29(26(19-38-30(25)27)31(40)22-6-2-1-3-7-22)23-8-4-9-24(17-23)37-18-21-14-12-20(13-15-21)16-28(36)39/h1-15,17,19,37H,16,18H2,(H2,36,39)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40	n/a	316	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...				Bioorg Med Chem 15: 3321-33 (2007) Article DOI: 10.1016/j.bmc.2007.03.013 BindingDB Entry DOI: 10.7270/Q2VH5M37
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta [154-461] (Homo sapiens (Human))	BDBM20015 (2-[4-({[3-(3-benzyl-8-chloroquinolin-4-yl)phenyl]a...) Show SMILES OC(=O)Cc1ccc(CNc2cccc(c2)-c2c(Cc3ccccc3)cnc3c(Cl)cccc23)cc1 Show InChI InChI=1S/C31H25ClN2O2/c32-28-11-5-10-27-30(25(20-34-31(27)28)16-21-6-2-1-3-7-21)24-8-4-9-26(18-24)33-19-23-14-12-22(13-15-23)17-29(35)36/h1-15,18,20,33H,16-17,19H2,(H,35,36)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40	n/a	23	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...				Bioorg Med Chem 15: 3321-33 (2007) Article DOI: 10.1016/j.bmc.2007.03.013 BindingDB Entry DOI: 10.7270/Q2VH5M37
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta [154-461] (Homo sapiens (Human))	BDBM20001 (2-{4-[({3-[3-benzyl-8-(trifluoromethyl)quinolin-4-...) Show SMILES OC(=O)Cc1ccc(CNc2cccc(c2)-c2c(Cc3ccccc3)cnc3c(cccc23)C(F)(F)F)cc1 Show InChI InChI=1S/C32H25F3N2O2/c33-32(34,35)28-11-5-10-27-30(25(20-37-31(27)28)16-21-6-2-1-3-7-21)24-8-4-9-26(18-24)36-19-23-14-12-22(13-15-23)17-29(38)39/h1-15,18,20,36H,16-17,19H2,(H,38,39)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.90	n/a	33	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...				Bioorg Med Chem 15: 3321-33 (2007) Article DOI: 10.1016/j.bmc.2007.03.013 BindingDB Entry DOI: 10.7270/Q2VH5M37
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta [154-461] (Homo sapiens (Human))	BDBM20004 (2-{4-[({3-[3-benzoyl-8-(trifluoromethyl)quinolin-4...) Show SMILES OC(=O)Cc1ccc(CNc2cccc(c2)-c2c(cnc3c(cccc23)C(F)(F)F)C(=O)c2ccccc2)cc1 Show InChI InChI=1S/C32H23F3N2O3/c33-32(34,35)27-11-5-10-25-29(26(19-37-30(25)27)31(40)22-6-2-1-3-7-22)23-8-4-9-24(17-23)36-18-21-14-12-20(13-15-21)16-28(38)39/h1-15,17,19,36H,16,18H2,(H,38,39)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.40	n/a	29	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...				Bioorg Med Chem 15: 3321-33 (2007) Article DOI: 10.1016/j.bmc.2007.03.013 BindingDB Entry DOI: 10.7270/Q2VH5M37
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta [154-461] (Homo sapiens (Human))	BDBM20020 (2-{4-[({3-[3-benzoyl-8-(trifluoromethyl)quinolin-4...) Show SMILES CC(C(O)=O)c1ccc(CNc2cccc(c2)-c2c(cnc3c(cccc23)C(F)(F)F)C(=O)c2ccccc2)cc1 Show InChI InChI=1S/C33H25F3N2O3/c1-20(32(40)41)22-15-13-21(14-16-22)18-37-25-10-5-9-24(17-25)29-26-11-6-12-28(33(34,35)36)30(26)38-19-27(29)31(39)23-7-3-2-4-8-23/h2-17,19-20,37H,18H2,1H3,(H,40,41)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.60	n/a	58	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...				Bioorg Med Chem 15: 3321-33 (2007) Article DOI: 10.1016/j.bmc.2007.03.013 BindingDB Entry DOI: 10.7270/Q2VH5M37
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta [154-461] (Homo sapiens (Human))	BDBM20014 (2-[4-({[3-(3-benzoyl-8-chloroquinolin-4-yl)phenyl]...) Show SMILES OC(=O)Cc1ccc(CNc2cccc(c2)-c2c(cnc3c(Cl)cccc23)C(=O)c2ccccc2)cc1 Show InChI InChI=1S/C31H23ClN2O3/c32-27-11-5-10-25-29(26(19-34-30(25)27)31(37)22-6-2-1-3-7-22)23-8-4-9-24(17-23)33-18-21-14-12-20(13-15-21)16-28(35)36/h1-15,17,19,33H,16,18H2,(H,35,36)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.70	n/a	39	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...				Bioorg Med Chem 15: 3321-33 (2007) Article DOI: 10.1016/j.bmc.2007.03.013 BindingDB Entry DOI: 10.7270/Q2VH5M37
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta [154-461] (Homo sapiens (Human))	BDBM20006 (2-{4-[({3-[3-phenyl-8-(trifluoromethyl)quinolin-4-...) Show SMILES OC(=O)Cc1ccc(CNc2cccc(c2)-c2c(cnc3c(cccc23)C(F)(F)F)-c2ccccc2)cc1 Show InChI InChI=1S/C31H23F3N2O2/c32-31(33,34)27-11-5-10-25-29(26(19-36-30(25)27)22-6-2-1-3-7-22)23-8-4-9-24(17-23)35-18-21-14-12-20(13-15-21)16-28(37)38/h1-15,17,19,35H,16,18H2,(H,37,38)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.70	n/a	44	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...				Bioorg Med Chem 15: 3321-33 (2007) Article DOI: 10.1016/j.bmc.2007.03.013 BindingDB Entry DOI: 10.7270/Q2VH5M37
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta [154-461] (Homo sapiens (Human))	BDBM20021 (2-{4-[({3-[3-benzoyl-8-(trifluoromethyl)quinolin-4...) Show SMILES CC(C)(C(O)=O)c1ccc(CNc2cccc(c2)-c2c(cnc3c(cccc23)C(F)(F)F)C(=O)c2ccccc2)cc1 Show InChI InChI=1S/C34H27F3N2O3/c1-33(2,32(41)42)24-16-14-21(15-17-24)19-38-25-11-6-10-23(18-25)29-26-12-7-13-28(34(35,36)37)30(26)39-20-27(29)31(40)22-8-4-3-5-9-22/h3-18,20,38H,19H2,1-2H3,(H,41,42)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.80	n/a	78	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...				Bioorg Med Chem 15: 3321-33 (2007) Article DOI: 10.1016/j.bmc.2007.03.013 BindingDB Entry DOI: 10.7270/Q2VH5M37
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta [154-461] (Homo sapiens (Human))	BDBM20005 (2-{4-[({3-[3-methyl-8-(trifluoromethyl)quinolin-4-...) Show SMILES Cc1cnc2c(cccc2c1-c1cccc(NCc2ccc(CC(O)=O)cc2)c1)C(F)(F)F Show InChI InChI=1S/C26H21F3N2O2/c1-16-14-31-25-21(6-3-7-22(25)26(27,28)29)24(16)19-4-2-5-20(13-19)30-15-18-10-8-17(9-11-18)12-23(32)33/h2-11,13-14,30H,12,15H2,1H3,(H,32,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.30	n/a	100	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...				Bioorg Med Chem 15: 3321-33 (2007) Article DOI: 10.1016/j.bmc.2007.03.013 BindingDB Entry DOI: 10.7270/Q2VH5M37
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta [154-461] (Homo sapiens (Human))	BDBM20011 (2-[4-({[3-(3-benzyl-8-methylquinolin-4-yl)phenyl]a...) Show SMILES Cc1cccc2c(c(Cc3ccccc3)cnc12)-c1cccc(NCc2ccc(CC(O)=O)cc2)c1 Show InChI InChI=1S/C32H28N2O2/c1-22-7-5-12-29-31(27(21-34-32(22)29)17-23-8-3-2-4-9-23)26-10-6-11-28(19-26)33-20-25-15-13-24(14-16-25)18-30(35)36/h2-16,19,21,33H,17-18,20H2,1H3,(H,35,36)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	90	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...				Bioorg Med Chem 15: 3321-33 (2007) Article DOI: 10.1016/j.bmc.2007.03.013 BindingDB Entry DOI: 10.7270/Q2VH5M37
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha [197-447] (Homo sapiens (Human))	BDBM20015 (2-[4-({[3-(3-benzyl-8-chloroquinolin-4-yl)phenyl]a...) Show SMILES OC(=O)Cc1ccc(CNc2cccc(c2)-c2c(Cc3ccccc3)cnc3c(Cl)cccc23)cc1 Show InChI InChI=1S/C31H25ClN2O2/c32-28-11-5-10-27-30(25(20-34-31(27)28)16-21-6-2-1-3-7-21)24-8-4-9-26(18-24)33-19-23-14-12-22(13-15-23)17-29(35)36/h1-15,18,20,33H,16-17,19H2,(H,35,36)	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	7.4	4
Wyeth Research					Assay Description Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...				Bioorg Med Chem 15: 3321-33 (2007) Article DOI: 10.1016/j.bmc.2007.03.013 BindingDB Entry DOI: 10.7270/Q2VH5M37
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta [154-461] (Homo sapiens (Human))	BDBM20025 (2-{4-[({3-[3-benzoyl-8-(trifluoromethyl)quinolin-4...) Show SMILES OCCc1ccc(CNc2cccc(c2)-c2c(cnc3c(cccc23)C(F)(F)F)C(=O)c2ccccc2)cc1 Show InChI InChI=1S/C32H25F3N2O2/c33-32(34,35)28-11-5-10-26-29(27(20-37-30(26)28)31(39)23-6-2-1-3-7-23)24-8-4-9-25(18-24)36-19-22-14-12-21(13-15-22)16-17-38/h1-15,18,20,36,38H,16-17,19H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.40	n/a	795	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...				Bioorg Med Chem 15: 3321-33 (2007) Article DOI: 10.1016/j.bmc.2007.03.013 BindingDB Entry DOI: 10.7270/Q2VH5M37
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta [154-461] (Homo sapiens (Human))	BDBM20010 (2-[4-({[3-(3-benzoyl-8-methylquinolin-4-yl)phenyl]...) Show SMILES Cc1cccc2c(-c3cccc(NCc4ccc(CC(O)=O)cc4)c3)c(cnc12)C(=O)c1ccccc1 Show InChI InChI=1S/C32H26N2O3/c1-21-7-5-12-27-30(28(20-34-31(21)27)32(37)24-8-3-2-4-9-24)25-10-6-11-26(18-25)33-19-23-15-13-22(14-16-23)17-29(35)36/h2-16,18,20,33H,17,19H2,1H3,(H,35,36)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.5	n/a	61	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...				Bioorg Med Chem 15: 3321-33 (2007) Article DOI: 10.1016/j.bmc.2007.03.013 BindingDB Entry DOI: 10.7270/Q2VH5M37
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta [154-461] (Homo sapiens (Human))	BDBM20016 (2-{3-[({3-[3-benzoyl-8-(trifluoromethyl)quinolin-4...) Show SMILES OC(=O)Cc1cccc(CNc2cccc(c2)-c2c(cnc3c(cccc23)C(F)(F)F)C(=O)c2ccccc2)c1 Show InChI InChI=1S/C32H23F3N2O3/c33-32(34,35)27-14-6-13-25-29(26(19-37-30(25)27)31(40)22-9-2-1-3-10-22)23-11-5-12-24(17-23)36-18-21-8-4-7-20(15-21)16-28(38)39/h1-15,17,19,36H,16,18H2,(H,38,39)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	141	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...				Bioorg Med Chem 15: 3321-33 (2007) Article DOI: 10.1016/j.bmc.2007.03.013 BindingDB Entry DOI: 10.7270/Q2VH5M37
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha [197-447] (Homo sapiens (Human))	BDBM20004 (2-{4-[({3-[3-benzoyl-8-(trifluoromethyl)quinolin-4...) Show SMILES OC(=O)Cc1ccc(CNc2cccc(c2)-c2c(cnc3c(cccc23)C(F)(F)F)C(=O)c2ccccc2)cc1 Show InChI InChI=1S/C32H23F3N2O3/c33-32(34,35)27-11-5-10-25-29(26(19-37-30(25)27)31(40)22-6-2-1-3-7-22)23-8-4-9-24(17-23)36-18-21-14-12-20(13-15-21)16-28(38)39/h1-15,17,19,36H,16,18H2,(H,38,39)	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	7.4	4
Wyeth Research					Assay Description Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...				Bioorg Med Chem 15: 3321-33 (2007) Article DOI: 10.1016/j.bmc.2007.03.013 BindingDB Entry DOI: 10.7270/Q2VH5M37
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha [197-447] (Homo sapiens (Human))	BDBM20001 (2-{4-[({3-[3-benzyl-8-(trifluoromethyl)quinolin-4-...) Show SMILES OC(=O)Cc1ccc(CNc2cccc(c2)-c2c(Cc3ccccc3)cnc3c(cccc23)C(F)(F)F)cc1 Show InChI InChI=1S/C32H25F3N2O2/c33-32(34,35)28-11-5-10-27-30(25(20-37-31(27)28)16-21-6-2-1-3-7-21)24-8-4-9-26(18-24)36-19-23-14-12-22(13-15-23)17-29(38)39/h1-15,18,20,36H,16-17,19H2,(H,38,39)	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7.60	n/a	n/a	n/a	n/a	7.4	4
Wyeth Research					Assay Description Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...				Bioorg Med Chem 15: 3321-33 (2007) Article DOI: 10.1016/j.bmc.2007.03.013 BindingDB Entry DOI: 10.7270/Q2VH5M37
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta [154-461] (Homo sapiens (Human))	BDBM20023 (2-{4-[({3-[3-benzoyl-8-(trifluoromethyl)quinolin-4...) Show SMILES OC(=O)C(F)(F)c1ccc(CNc2cccc(c2)-c2c(cnc3c(cccc23)C(F)(F)F)C(=O)c2ccccc2)cc1 Show InChI InChI=1S/C32H21F5N2O3/c33-31(34,30(41)42)22-14-12-19(13-15-22)17-38-23-9-4-8-21(16-23)27-24-10-5-11-26(32(35,36)37)28(24)39-18-25(27)29(40)20-6-2-1-3-7-20/h1-16,18,38H,17H2,(H,41,42)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.80	n/a	2.40E+3	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...				Bioorg Med Chem 15: 3321-33 (2007) Article DOI: 10.1016/j.bmc.2007.03.013 BindingDB Entry DOI: 10.7270/Q2VH5M37
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha [197-447] (Homo sapiens (Human))	BDBM20006 (2-{4-[({3-[3-phenyl-8-(trifluoromethyl)quinolin-4-...) Show SMILES OC(=O)Cc1ccc(CNc2cccc(c2)-c2c(cnc3c(cccc23)C(F)(F)F)-c2ccccc2)cc1 Show InChI InChI=1S/C31H23F3N2O2/c32-31(33,34)27-11-5-10-25-29(26(19-36-30(25)27)22-6-2-1-3-7-22)23-8-4-9-24(17-23)35-18-21-14-12-20(13-15-21)16-28(37)38/h1-15,17,19,35H,16,18H2,(H,37,38)	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	7.4	4
Wyeth Research					Assay Description Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...				Bioorg Med Chem 15: 3321-33 (2007) Article DOI: 10.1016/j.bmc.2007.03.013 BindingDB Entry DOI: 10.7270/Q2VH5M37
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta [154-461] (Homo sapiens (Human))	BDBM20022 (2-{4-[({3-[3-benzoyl-8-(trifluoromethyl)quinolin-4...) Show SMILES OC(C(O)=O)c1ccc(CNc2cccc(c2)-c2c(cnc3c(cccc23)C(F)(F)F)C(=O)c2ccccc2)cc1 Show InChI InChI=1S/C32H23F3N2O4/c33-32(34,35)26-11-5-10-24-27(25(18-37-28(24)26)29(38)20-6-2-1-3-7-20)22-8-4-9-23(16-22)36-17-19-12-14-21(15-13-19)30(39)31(40)41/h1-16,18,30,36,39H,17H2,(H,40,41)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.5	n/a	4.00E+3	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...				Bioorg Med Chem 15: 3321-33 (2007) Article DOI: 10.1016/j.bmc.2007.03.013 BindingDB Entry DOI: 10.7270/Q2VH5M37
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha [197-447] (Homo sapiens (Human))	BDBM20014 (2-[4-({[3-(3-benzoyl-8-chloroquinolin-4-yl)phenyl]...) Show SMILES OC(=O)Cc1ccc(CNc2cccc(c2)-c2c(cnc3c(Cl)cccc23)C(=O)c2ccccc2)cc1 Show InChI InChI=1S/C31H23ClN2O3/c32-27-11-5-10-25-29(26(19-34-30(25)27)31(37)22-6-2-1-3-7-22)23-8-4-9-24(17-23)33-18-21-14-12-20(13-15-21)16-28(35)36/h1-15,17,19,33H,16,18H2,(H,35,36)	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	7.4	4
Wyeth Research					Assay Description Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...				Bioorg Med Chem 15: 3321-33 (2007) Article DOI: 10.1016/j.bmc.2007.03.013 BindingDB Entry DOI: 10.7270/Q2VH5M37
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha [197-447] (Homo sapiens (Human))	BDBM20024 (2-{4-[({3-[3-benzoyl-8-(trifluoromethyl)quinolin-4...) Show SMILES NC(=O)Cc1ccc(CNc2cccc(c2)-c2c(cnc3c(cccc23)C(F)(F)F)C(=O)c2ccccc2)cc1 Show InChI InChI=1S/C32H24F3N3O2/c33-32(34,35)27-11-5-10-25-29(26(19-38-30(25)27)31(40)22-6-2-1-3-7-22)23-8-4-9-24(17-23)37-18-21-14-12-20(13-15-21)16-28(36)39/h1-15,17,19,37H,16,18H2,(H2,36,39)	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	7.4	4
Wyeth Research					Assay Description Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...				Bioorg Med Chem 15: 3321-33 (2007) Article DOI: 10.1016/j.bmc.2007.03.013 BindingDB Entry DOI: 10.7270/Q2VH5M37
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta [154-461] (Homo sapiens (Human))	BDBM20017 (2-{4-[({3-[3-benzoyl-8-(trifluoromethyl)quinolin-4...) Show SMILES OC(=O)COc1ccc(CNc2cccc(c2)-c2c(cnc3c(cccc23)C(F)(F)F)C(=O)c2ccccc2)cc1 Show InChI InChI=1S/C32H23F3N2O4/c33-32(34,35)27-11-5-10-25-29(26(18-37-30(25)27)31(40)21-6-2-1-3-7-21)22-8-4-9-23(16-22)36-17-20-12-14-24(15-13-20)41-19-28(38)39/h1-16,18,36H,17,19H2,(H,38,39)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	1.27E+3	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...				Bioorg Med Chem 15: 3321-33 (2007) Article DOI: 10.1016/j.bmc.2007.03.013 BindingDB Entry DOI: 10.7270/Q2VH5M37
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta [154-461] (Homo sapiens (Human))	BDBM20027 (methyl alcohol analogue,39 | {4-[({3-[3-benzoyl-8-...) Show SMILES OCc1ccc(CNc2cccc(c2)-c2c(cnc3c(cccc23)C(F)(F)F)C(=O)c2ccccc2)cc1 Show InChI InChI=1S/C31H23F3N2O2/c32-31(33,34)27-11-5-10-25-28(26(18-36-29(25)27)30(38)22-6-2-1-3-7-22)23-8-4-9-24(16-23)35-17-20-12-14-21(19-37)15-13-20/h1-16,18,35,37H,17,19H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12.8	n/a	2.30E+3	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...				Bioorg Med Chem 15: 3321-33 (2007) Article DOI: 10.1016/j.bmc.2007.03.013 BindingDB Entry DOI: 10.7270/Q2VH5M37
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha [197-447] (Homo sapiens (Human))	BDBM20020 (2-{4-[({3-[3-benzoyl-8-(trifluoromethyl)quinolin-4...) Show SMILES CC(C(O)=O)c1ccc(CNc2cccc(c2)-c2c(cnc3c(cccc23)C(F)(F)F)C(=O)c2ccccc2)cc1 Show InChI InChI=1S/C33H25F3N2O3/c1-20(32(40)41)22-15-13-21(14-16-22)18-37-25-10-5-9-24(17-25)29-26-11-6-12-28(33(34,35)36)30(26)38-19-27(29)31(39)23-7-3-2-4-8-23/h2-17,19-20,37H,18H2,1H3,(H,40,41)	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15.2	n/a	n/a	n/a	n/a	7.4	4
Wyeth Research					Assay Description Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...				Bioorg Med Chem 15: 3321-33 (2007) Article DOI: 10.1016/j.bmc.2007.03.013 BindingDB Entry DOI: 10.7270/Q2VH5M37
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha [197-447] (Homo sapiens (Human))	BDBM20005 (2-{4-[({3-[3-methyl-8-(trifluoromethyl)quinolin-4-...) Show SMILES Cc1cnc2c(cccc2c1-c1cccc(NCc2ccc(CC(O)=O)cc2)c1)C(F)(F)F Show InChI InChI=1S/C26H21F3N2O2/c1-16-14-31-25-21(6-3-7-22(25)26(27,28)29)24(16)19-4-2-5-20(13-19)30-15-18-10-8-17(9-11-18)12-23(32)33/h2-11,13-14,30H,12,15H2,1H3,(H,32,33)	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	7.4	4
Wyeth Research					Assay Description Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...				Bioorg Med Chem 15: 3321-33 (2007) Article DOI: 10.1016/j.bmc.2007.03.013 BindingDB Entry DOI: 10.7270/Q2VH5M37
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta [154-461] (Homo sapiens (Human))	BDBM20012 (2-[4-({[3-(3-benzoyl-8-fluoroquinolin-4-yl)phenyl]...) Show SMILES OC(=O)Cc1ccc(CNc2cccc(c2)-c2c(cnc3c(F)cccc23)C(=O)c2ccccc2)cc1 Show InChI InChI=1S/C31H23FN2O3/c32-27-11-5-10-25-29(26(19-34-30(25)27)31(37)22-6-2-1-3-7-22)23-8-4-9-24(17-23)33-18-21-14-12-20(13-15-21)16-28(35)36/h1-15,17,19,33H,16,18H2,(H,35,36)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	700	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...				Bioorg Med Chem 15: 3321-33 (2007) Article DOI: 10.1016/j.bmc.2007.03.013 BindingDB Entry DOI: 10.7270/Q2VH5M37
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha [197-447] (Homo sapiens (Human))	BDBM20021 (2-{4-[({3-[3-benzoyl-8-(trifluoromethyl)quinolin-4...) Show SMILES CC(C)(C(O)=O)c1ccc(CNc2cccc(c2)-c2c(cnc3c(cccc23)C(F)(F)F)C(=O)c2ccccc2)cc1 Show InChI InChI=1S/C34H27F3N2O3/c1-33(2,32(41)42)24-16-14-21(15-17-24)19-38-25-11-6-10-23(18-25)29-26-12-7-13-28(34(35,36)37)30(26)39-20-27(29)31(40)22-8-4-3-5-9-22/h3-18,20,38H,19H2,1-2H3,(H,41,42)	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17.2	n/a	n/a	n/a	n/a	7.4	4
Wyeth Research					Assay Description Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...				Bioorg Med Chem 15: 3321-33 (2007) Article DOI: 10.1016/j.bmc.2007.03.013 BindingDB Entry DOI: 10.7270/Q2VH5M37
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha [197-447] (Homo sapiens (Human))	BDBM20010 (2-[4-({[3-(3-benzoyl-8-methylquinolin-4-yl)phenyl]...) Show SMILES Cc1cccc2c(-c3cccc(NCc4ccc(CC(O)=O)cc4)c3)c(cnc12)C(=O)c1ccccc1 Show InChI InChI=1S/C32H26N2O3/c1-21-7-5-12-27-30(28(20-34-31(21)27)32(37)24-8-3-2-4-9-24)25-10-6-11-26(18-25)33-19-23-15-13-22(14-16-23)17-29(35)36/h2-16,18,20,33H,17,19H2,1H3,(H,35,36)	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	7.4	4
Wyeth Research					Assay Description Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...				Bioorg Med Chem 15: 3321-33 (2007) Article DOI: 10.1016/j.bmc.2007.03.013 BindingDB Entry DOI: 10.7270/Q2VH5M37
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha [197-447] (Homo sapiens (Human))	BDBM20011 (2-[4-({[3-(3-benzyl-8-methylquinolin-4-yl)phenyl]a...) Show SMILES Cc1cccc2c(c(Cc3ccccc3)cnc12)-c1cccc(NCc2ccc(CC(O)=O)cc2)c1 Show InChI InChI=1S/C32H28N2O2/c1-22-7-5-12-29-31(27(21-34-32(22)29)17-23-8-3-2-4-9-23)26-10-6-11-28(19-26)33-20-25-15-13-24(14-16-25)18-30(35)36/h2-16,19,21,33H,17-18,20H2,1H3,(H,35,36)	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	7.4	4
Wyeth Research					Assay Description Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...				Bioorg Med Chem 15: 3321-33 (2007) Article DOI: 10.1016/j.bmc.2007.03.013 BindingDB Entry DOI: 10.7270/Q2VH5M37
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha [197-447] (Homo sapiens (Human))	BDBM20023 (2-{4-[({3-[3-benzoyl-8-(trifluoromethyl)quinolin-4...) Show SMILES OC(=O)C(F)(F)c1ccc(CNc2cccc(c2)-c2c(cnc3c(cccc23)C(F)(F)F)C(=O)c2ccccc2)cc1 Show InChI InChI=1S/C32H21F5N2O3/c33-31(34,30(41)42)22-14-12-19(13-15-22)17-38-23-9-4-8-21(16-23)27-24-10-5-11-26(32(35,36)37)28(24)39-18-25(27)29(40)20-6-2-1-3-7-20/h1-16,18,38H,17H2,(H,41,42)	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30.2	n/a	n/a	n/a	n/a	7.4	4
Wyeth Research					Assay Description Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...				Bioorg Med Chem 15: 3321-33 (2007) Article DOI: 10.1016/j.bmc.2007.03.013 BindingDB Entry DOI: 10.7270/Q2VH5M37
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha [197-447] (Homo sapiens (Human))	BDBM20022 (2-{4-[({3-[3-benzoyl-8-(trifluoromethyl)quinolin-4...) Show SMILES OC(C(O)=O)c1ccc(CNc2cccc(c2)-c2c(cnc3c(cccc23)C(F)(F)F)C(=O)c2ccccc2)cc1 Show InChI InChI=1S/C32H23F3N2O4/c33-32(34,35)26-11-5-10-24-27(25(18-37-28(24)26)29(38)20-6-2-1-3-7-20)22-8-4-9-23(16-22)36-17-19-12-14-21(15-13-19)30(39)31(40)41/h1-16,18,30,36,39H,17H2,(H,40,41)	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	33.6	n/a	n/a	n/a	n/a	7.4	4
Wyeth Research					Assay Description Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...				Bioorg Med Chem 15: 3321-33 (2007) Article DOI: 10.1016/j.bmc.2007.03.013 BindingDB Entry DOI: 10.7270/Q2VH5M37
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha [197-447] (Homo sapiens (Human))	BDBM20016 (2-{3-[({3-[3-benzoyl-8-(trifluoromethyl)quinolin-4...) Show SMILES OC(=O)Cc1cccc(CNc2cccc(c2)-c2c(cnc3c(cccc23)C(F)(F)F)C(=O)c2ccccc2)c1 Show InChI InChI=1S/C32H23F3N2O3/c33-32(34,35)27-14-6-13-25-29(26(19-37-30(25)27)31(40)22-9-2-1-3-10-22)23-11-5-12-24(17-23)36-18-21-8-4-7-20(15-21)16-28(38)39/h1-15,17,19,36H,16,18H2,(H,38,39)	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	33.6	n/a	n/a	n/a	n/a	7.4	4
Wyeth Research					Assay Description Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...				Bioorg Med Chem 15: 3321-33 (2007) Article DOI: 10.1016/j.bmc.2007.03.013 BindingDB Entry DOI: 10.7270/Q2VH5M37
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta [154-461] (Homo sapiens (Human))	BDBM20008 (2-{4-[({3-[3-cyano-8-(trifluoromethyl)quinolin-4-y...) Show SMILES OC(=O)Cc1ccc(CNc2cccc(c2)-c2c(cnc3c(cccc23)C(F)(F)F)C#N)cc1 Show InChI InChI=1S/C26H18F3N3O2/c27-26(28,29)22-6-2-5-21-24(19(13-30)15-32-25(21)22)18-3-1-4-20(12-18)31-14-17-9-7-16(8-10-17)11-23(33)34/h1-10,12,15,31H,11,14H2,(H,33,34)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	33.8	n/a	450	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...				Bioorg Med Chem 15: 3321-33 (2007) Article DOI: 10.1016/j.bmc.2007.03.013 BindingDB Entry DOI: 10.7270/Q2VH5M37
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha [197-447] (Homo sapiens (Human))	BDBM20025 (2-{4-[({3-[3-benzoyl-8-(trifluoromethyl)quinolin-4...) Show SMILES OCCc1ccc(CNc2cccc(c2)-c2c(cnc3c(cccc23)C(F)(F)F)C(=O)c2ccccc2)cc1 Show InChI InChI=1S/C32H25F3N2O2/c33-32(34,35)28-11-5-10-26-29(27(20-37-30(26)28)31(39)23-6-2-1-3-7-23)24-8-4-9-25(18-24)36-19-22-14-12-21(13-15-22)16-17-38/h1-15,18,20,36,38H,16-17,19H2	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	7.4	4
Wyeth Research					Assay Description Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...				Bioorg Med Chem 15: 3321-33 (2007) Article DOI: 10.1016/j.bmc.2007.03.013 BindingDB Entry DOI: 10.7270/Q2VH5M37
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta [154-461] (Homo sapiens (Human))	BDBM20026 (3-[3-benzoyl-8-(trifluoromethyl)quinolin-4-yl]-N-b...) Show SMILES FC(F)(F)c1cccc2c(-c3cccc(NCc4ccccc4)c3)c(cnc12)C(=O)c1ccccc1 Show InChI InChI=1S/C30H21F3N2O/c31-30(32,33)26-16-8-15-24-27(25(19-35-28(24)26)29(36)21-11-5-2-6-12-21)22-13-7-14-23(17-22)34-18-20-9-3-1-4-10-20/h1-17,19,34H,18H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	45	n/a	770	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...				Bioorg Med Chem 15: 3321-33 (2007) Article DOI: 10.1016/j.bmc.2007.03.013 BindingDB Entry DOI: 10.7270/Q2VH5M37
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta [154-461] (Homo sapiens (Human))	BDBM20007 (2-(4-{[(3-{3-[hydroxy(phenyl)methyl]-8-(trifluorom...) Show SMILES OC(c1ccccc1)c1cnc2c(cccc2c1-c1cccc(NCc2ccc(CC(O)=O)cc2)c1)C(F)(F)F Show InChI InChI=1S/C32H25F3N2O3/c33-32(34,35)27-11-5-10-25-29(26(19-37-30(25)27)31(40)22-6-2-1-3-7-22)23-8-4-9-24(17-23)36-18-21-14-12-20(13-15-21)16-28(38)39/h1-15,17,19,31,36,40H,16,18H2,(H,38,39)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	56.4	n/a	812	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...				Bioorg Med Chem 15: 3321-33 (2007) Article DOI: 10.1016/j.bmc.2007.03.013 BindingDB Entry DOI: 10.7270/Q2VH5M37
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha [197-447] (Homo sapiens (Human))	BDBM20017 (2-{4-[({3-[3-benzoyl-8-(trifluoromethyl)quinolin-4...) Show SMILES OC(=O)COc1ccc(CNc2cccc(c2)-c2c(cnc3c(cccc23)C(F)(F)F)C(=O)c2ccccc2)cc1 Show InChI InChI=1S/C32H23F3N2O4/c33-32(34,35)27-11-5-10-25-29(26(18-37-30(25)27)31(40)21-6-2-1-3-7-21)22-8-4-9-23(16-22)36-17-20-12-14-24(15-13-20)41-19-28(38)39/h1-16,18,36H,17,19H2,(H,38,39)	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	63.9	n/a	n/a	n/a	n/a	7.4	4
Wyeth Research					Assay Description Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...				Bioorg Med Chem 15: 3321-33 (2007) Article DOI: 10.1016/j.bmc.2007.03.013 BindingDB Entry DOI: 10.7270/Q2VH5M37
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha [197-447] (Homo sapiens (Human))	BDBM20027 (methyl alcohol analogue,39 | {4-[({3-[3-benzoyl-8-...) Show SMILES OCc1ccc(CNc2cccc(c2)-c2c(cnc3c(cccc23)C(F)(F)F)C(=O)c2ccccc2)cc1 Show InChI InChI=1S/C31H23F3N2O2/c32-31(33,34)27-11-5-10-25-28(26(18-36-29(25)27)30(38)22-6-2-1-3-7-22)23-8-4-9-24(16-23)35-17-20-12-14-21(19-37)15-13-20/h1-16,18,35,37H,17,19H2	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	90.5	n/a	n/a	n/a	n/a	7.4	4
Wyeth Research					Assay Description Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...				Bioorg Med Chem 15: 3321-33 (2007) Article DOI: 10.1016/j.bmc.2007.03.013 BindingDB Entry DOI: 10.7270/Q2VH5M37
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha [197-447] (Homo sapiens (Human))	BDBM20012 (2-[4-({[3-(3-benzoyl-8-fluoroquinolin-4-yl)phenyl]...) Show SMILES OC(=O)Cc1ccc(CNc2cccc(c2)-c2c(cnc3c(F)cccc23)C(=O)c2ccccc2)cc1 Show InChI InChI=1S/C31H23FN2O3/c32-27-11-5-10-25-29(26(19-34-30(25)27)31(37)22-6-2-1-3-7-22)23-8-4-9-24(17-23)33-18-21-14-12-20(13-15-21)16-28(35)36/h1-15,17,19,33H,16,18H2,(H,35,36)	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	104	n/a	n/a	n/a	n/a	7.4	4
Wyeth Research					Assay Description Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...				Bioorg Med Chem 15: 3321-33 (2007) Article DOI: 10.1016/j.bmc.2007.03.013 BindingDB Entry DOI: 10.7270/Q2VH5M37
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta [154-461] (Homo sapiens (Human))	BDBM20019 (4-[({3-[3-benzoyl-8-(trifluoromethyl)quinolin-4-yl...) Show SMILES OC(=O)c1ccc(CNc2cccc(c2)-c2c(cnc3c(cccc23)C(F)(F)F)C(=O)c2ccccc2)cc1 Show InChI InChI=1S/C31H21F3N2O3/c32-31(33,34)26-11-5-10-24-27(25(18-36-28(24)26)29(37)20-6-2-1-3-7-20)22-8-4-9-23(16-22)35-17-19-12-14-21(15-13-19)30(38)39/h1-16,18,35H,17H2,(H,38,39)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	138	n/a	365	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...				Bioorg Med Chem 15: 3321-33 (2007) Article DOI: 10.1016/j.bmc.2007.03.013 BindingDB Entry DOI: 10.7270/Q2VH5M37
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha [197-447] (Homo sapiens (Human))	BDBM20008 (2-{4-[({3-[3-cyano-8-(trifluoromethyl)quinolin-4-y...) Show SMILES OC(=O)Cc1ccc(CNc2cccc(c2)-c2c(cnc3c(cccc23)C(F)(F)F)C#N)cc1 Show InChI InChI=1S/C26H18F3N3O2/c27-26(28,29)22-6-2-5-21-24(19(13-30)15-32-25(21)22)18-3-1-4-20(12-18)31-14-17-9-7-16(8-10-17)11-23(33)34/h1-10,12,15,31H,11,14H2,(H,33,34)	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	7.4	4
Wyeth Research					Assay Description Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...				Bioorg Med Chem 15: 3321-33 (2007) Article DOI: 10.1016/j.bmc.2007.03.013 BindingDB Entry DOI: 10.7270/Q2VH5M37
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta [154-461] (Homo sapiens (Human))	BDBM20013 (2-[4-({[3-(3-benzoylquinolin-4-yl)phenyl]amino}met...) Show SMILES OC(=O)Cc1ccc(CNc2cccc(c2)-c2c(cnc3ccccc23)C(=O)c2ccccc2)cc1 Show InChI InChI=1S/C31H24N2O3/c34-29(35)17-21-13-15-22(16-14-21)19-32-25-10-6-9-24(18-25)30-26-11-4-5-12-28(26)33-20-27(30)31(36)23-7-2-1-3-8-23/h1-16,18,20,32H,17,19H2,(H,34,35)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	154	n/a	1.65E+3	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...				Bioorg Med Chem 15: 3321-33 (2007) Article DOI: 10.1016/j.bmc.2007.03.013 BindingDB Entry DOI: 10.7270/Q2VH5M37
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha [197-447] (Homo sapiens (Human))	BDBM20026 (3-[3-benzoyl-8-(trifluoromethyl)quinolin-4-yl]-N-b...) Show SMILES FC(F)(F)c1cccc2c(-c3cccc(NCc4ccccc4)c3)c(cnc12)C(=O)c1ccccc1 Show InChI InChI=1S/C30H21F3N2O/c31-30(32,33)26-16-8-15-24-27(25(19-35-28(24)26)29(36)21-11-5-2-6-12-21)22-13-7-14-23(17-22)34-18-20-9-3-1-4-10-20/h1-17,19,34H,18H2	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	241	n/a	n/a	n/a	n/a	7.4	4
Wyeth Research					Assay Description Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...				Bioorg Med Chem 15: 3321-33 (2007) Article DOI: 10.1016/j.bmc.2007.03.013 BindingDB Entry DOI: 10.7270/Q2VH5M37
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta [154-461] (Homo sapiens (Human))	BDBM20028 ((5Z)-5-({4-[({3-[3-benzoyl-8-(trifluoromethyl)quin...) Show SMILES FC(F)(F)c1cccc2c(-c3cccc(NCc4ccc(\C=C5/SC(=O)NC5=O)cc4)c3)c(cnc12)C(=O)c1ccccc1 Show InChI InChI=1S/C34H22F3N3O3S/c35-34(36,37)27-11-5-10-25-29(26(19-39-30(25)27)31(41)22-6-2-1-3-7-22)23-8-4-9-24(17-23)38-18-21-14-12-20(13-15-21)16-28-32(42)40-33(43)44-28/h1-17,19,38H,18H2,(H,40,42,43)/b28-16-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	276	n/a	369	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...				Bioorg Med Chem 15: 3321-33 (2007) Article DOI: 10.1016/j.bmc.2007.03.013 BindingDB Entry DOI: 10.7270/Q2VH5M37
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta [154-461] (Homo sapiens (Human))	BDBM20029 ((5Z)-5-({4-[({3-[3-benzoyl-8-(trifluoromethyl)quin...) Show SMILES FC(F)(F)c1cccc2c(-c3cccc(NCc4ccc(\C=C5/SC(=S)NC5=O)cc4)c3)c(cnc12)C(=O)c1ccccc1 Show InChI InChI=1S/C34H22F3N3O2S2/c35-34(36,37)27-11-5-10-25-29(26(19-39-30(25)27)31(41)22-6-2-1-3-7-22)23-8-4-9-24(17-23)38-18-21-14-12-20(13-15-21)16-28-32(42)40-33(43)44-28/h1-17,19,38H,18H2,(H,40,42,43)/b28-16-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	310	n/a	286	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...				Bioorg Med Chem 15: 3321-33 (2007) Article DOI: 10.1016/j.bmc.2007.03.013 BindingDB Entry DOI: 10.7270/Q2VH5M37
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha [197-447] (Homo sapiens (Human))	BDBM20007 (2-(4-{[(3-{3-[hydroxy(phenyl)methyl]-8-(trifluorom...) Show SMILES OC(c1ccccc1)c1cnc2c(cccc2c1-c1cccc(NCc2ccc(CC(O)=O)cc2)c1)C(F)(F)F Show InChI InChI=1S/C32H25F3N2O3/c33-32(34,35)27-11-5-10-25-29(26(19-37-30(25)27)31(40)22-6-2-1-3-7-22)23-8-4-9-24(17-23)36-18-21-14-12-20(13-15-21)16-28(38)39/h1-15,17,19,31,36,40H,16,18H2,(H,38,39)	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	384	n/a	n/a	n/a	n/a	7.4	4
Wyeth Research					Assay Description Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...				Bioorg Med Chem 15: 3321-33 (2007) Article DOI: 10.1016/j.bmc.2007.03.013 BindingDB Entry DOI: 10.7270/Q2VH5M37
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha [197-447] (Homo sapiens (Human))	BDBM20019 (4-[({3-[3-benzoyl-8-(trifluoromethyl)quinolin-4-yl...) Show SMILES OC(=O)c1ccc(CNc2cccc(c2)-c2c(cnc3c(cccc23)C(F)(F)F)C(=O)c2ccccc2)cc1 Show InChI InChI=1S/C31H21F3N2O3/c32-31(33,34)26-11-5-10-24-27(25(18-36-28(24)26)29(37)20-6-2-1-3-7-20)22-8-4-9-23(16-22)35-17-19-12-14-21(15-13-19)30(38)39/h1-16,18,35H,17H2,(H,38,39)	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	420	n/a	n/a	n/a	n/a	7.4	4
Wyeth Research					Assay Description Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...				Bioorg Med Chem 15: 3321-33 (2007) Article DOI: 10.1016/j.bmc.2007.03.013 BindingDB Entry DOI: 10.7270/Q2VH5M37
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha [197-447] (Homo sapiens (Human))	BDBM20028 ((5Z)-5-({4-[({3-[3-benzoyl-8-(trifluoromethyl)quin...) Show SMILES FC(F)(F)c1cccc2c(-c3cccc(NCc4ccc(\C=C5/SC(=O)NC5=O)cc4)c3)c(cnc12)C(=O)c1ccccc1 Show InChI InChI=1S/C34H22F3N3O3S/c35-34(36,37)27-11-5-10-25-29(26(19-39-30(25)27)31(41)22-6-2-1-3-7-22)23-8-4-9-24(17-23)38-18-21-14-12-20(13-15-21)16-28-32(42)40-33(43)44-28/h1-17,19,38H,18H2,(H,40,42,43)/b28-16-	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	456	n/a	n/a	n/a	n/a	7.4	4
Wyeth Research					Assay Description Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...				Bioorg Med Chem 15: 3321-33 (2007) Article DOI: 10.1016/j.bmc.2007.03.013 BindingDB Entry DOI: 10.7270/Q2VH5M37
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha [197-447] (Homo sapiens (Human))	BDBM20029 ((5Z)-5-({4-[({3-[3-benzoyl-8-(trifluoromethyl)quin...) Show SMILES FC(F)(F)c1cccc2c(-c3cccc(NCc4ccc(\C=C5/SC(=S)NC5=O)cc4)c3)c(cnc12)C(=O)c1ccccc1 Show InChI InChI=1S/C34H22F3N3O2S2/c35-34(36,37)27-11-5-10-25-29(26(19-39-30(25)27)31(41)22-6-2-1-3-7-22)23-8-4-9-24(17-23)38-18-21-14-12-20(13-15-21)16-28-32(42)40-33(43)44-28/h1-17,19,38H,18H2,(H,40,42,43)/b28-16-	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	479	n/a	n/a	n/a	n/a	7.4	4
Wyeth Research					Assay Description Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...				Bioorg Med Chem 15: 3321-33 (2007) Article DOI: 10.1016/j.bmc.2007.03.013 BindingDB Entry DOI: 10.7270/Q2VH5M37
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha [197-447] (Homo sapiens (Human))	BDBM20013 (2-[4-({[3-(3-benzoylquinolin-4-yl)phenyl]amino}met...) Show SMILES OC(=O)Cc1ccc(CNc2cccc(c2)-c2c(cnc3ccccc23)C(=O)c2ccccc2)cc1 Show InChI InChI=1S/C31H24N2O3/c34-29(35)17-21-13-15-22(16-14-21)19-32-25-10-6-9-24(18-25)30-26-11-4-5-12-28(26)33-20-27(30)31(36)23-7-2-1-3-8-23/h1-16,18,20,32H,17,19H2,(H,34,35)	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	650	n/a	n/a	n/a	n/a	7.4	4
Wyeth Research					Assay Description Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...				Bioorg Med Chem 15: 3321-33 (2007) Article DOI: 10.1016/j.bmc.2007.03.013 BindingDB Entry DOI: 10.7270/Q2VH5M37
					More data for this Ligand-Target Pair

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