Compile Data Set for Download or QSAR

Found 47 hits Enz. Inhib. hit(s) with all data for entry = 8577   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM259953 (US9512121, 37) Show SMILES COc1c(cnc2ccc(Sc3nnc4ccc(cn34)-c3cnn(C)c3)cc12)-c1cnn(C)c1 Show InChI InChI=1S/C24H20N8OS/c1-30-12-16(9-26-30)15-4-7-22-28-29-24(32(22)14-15)34-18-5-6-21-19(8-18)23(33-3)20(11-25-21)17-10-27-31(2)13-17/h4-14H,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	20
Jiangsu Hansoh Pharmaceutical Co., Ltd. US Patent					Assay Description Experimental Purpose: The purpose is to study the effect of the compounds on c-MET tyrosine kinase activity at the molecular level. IC50 values were ...				US Patent US9512121 (2016) BindingDB Entry DOI: 10.7270/Q2ST7NSV
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM259964 (US9512121, 48) Show SMILES COc1c(cnc2ccc(Sc3nnc4ccc(cn34)-c3cnn(C)c3)cc12)-c1cnn(CCO)c1 Show InChI InChI=1S/C25H22N8O2S/c1-31-13-17(10-27-31)16-3-6-23-29-30-25(33(23)15-16)36-19-4-5-22-20(9-19)24(35-2)21(12-26-22)18-11-28-32(14-18)7-8-34/h3-6,9-15,34H,7-8H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	20
Jiangsu Hansoh Pharmaceutical Co., Ltd. US Patent					Assay Description Experimental Purpose: The purpose is to study the effect of the compounds on c-MET tyrosine kinase activity at the molecular level. IC50 values were ...				US Patent US9512121 (2016) BindingDB Entry DOI: 10.7270/Q2ST7NSV
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM259956 (US9512121, 40) Show SMILES COc1c(cnc2ccc(Sc3nnc4c(F)cc(cn34)-c3cnn(C)c3)cc12)-c1cnn(C)c1 Show InChI InChI=1S/C24H19FN8OS/c1-31-11-15(8-27-31)14-6-20(25)23-29-30-24(33(23)13-14)35-17-4-5-21-18(7-17)22(34-3)19(10-26-21)16-9-28-32(2)12-16/h4-13H,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	20
Jiangsu Hansoh Pharmaceutical Co., Ltd. US Patent					Assay Description Experimental Purpose: The purpose is to study the effect of the compounds on c-MET tyrosine kinase activity at the molecular level. IC50 values were ...				US Patent US9512121 (2016) BindingDB Entry DOI: 10.7270/Q2ST7NSV
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50182493 (CHEMBL3818247 | US9512121, 22) Show SMILES CN1C(=O)COc2c1cnc1ccc(Sc3nnc4c(F)cc(cn34)-c3cnn(C)c3)cc21 Show InChI InChI=1S/C22H16FN7O2S/c1-28-9-13(7-25-28)12-5-16(23)21-26-27-22(30(21)10-12)33-14-3-4-17-15(6-14)20-18(8-24-17)29(2)19(31)11-32-20/h3-10H,11H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a	20
Jiangsu Hansoh Pharmaceutical Co., Ltd. US Patent					Assay Description Experimental Purpose: The purpose is to study the effect of the compounds on c-MET tyrosine kinase activity at the molecular level. IC50 values were ...				US Patent US9512121 (2016) BindingDB Entry DOI: 10.7270/Q2ST7NSV
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM259930 (US9512121, 5) Show SMILES Cn1cc(cn1)-c1cc(F)c2nnc(Sc3ccc4ncc(-c5cnn(C)c5)c(F)c4c3)n2c1 Show InChI InChI=1S/C23H16F2N8S/c1-31-10-14(7-27-31)13-5-19(24)22-29-30-23(33(22)12-13)34-16-3-4-20-17(6-16)21(25)18(9-26-20)15-8-28-32(2)11-15/h3-12H,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a	20
Jiangsu Hansoh Pharmaceutical Co., Ltd. US Patent					Assay Description Experimental Purpose: The purpose is to study the effect of the compounds on c-MET tyrosine kinase activity at the molecular level. IC50 values were ...				US Patent US9512121 (2016) BindingDB Entry DOI: 10.7270/Q2ST7NSV
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM259957 (US9512121, 41) Show SMILES Cn1cc(cn1)-c1ccc2nnc(Sc3ccc4ncc(-c5cnn(C)c5)c(F)c4c3)n2c1 Show InChI InChI=1S/C23H17FN8S/c1-30-11-15(8-26-30)14-3-6-21-28-29-23(32(21)13-14)33-17-4-5-20-18(7-17)22(24)19(10-25-20)16-9-27-31(2)12-16/h3-13H,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	20
Jiangsu Hansoh Pharmaceutical Co., Ltd. US Patent					Assay Description Experimental Purpose: The purpose is to study the effect of the compounds on c-MET tyrosine kinase activity at the molecular level. IC50 values were ...				US Patent US9512121 (2016) BindingDB Entry DOI: 10.7270/Q2ST7NSV
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM259931 (US9512121, 6) Show SMILES COc1c(cnc2ccc(Sc3nnc4c(F)cc(cn34)-c3cnn(C)c3)cc12)N1CCOC1=O Show InChI InChI=1S/C23H18FN7O3S/c1-29-11-14(9-26-29)13-7-17(24)21-27-28-22(31(21)12-13)35-15-3-4-18-16(8-15)20(33-2)19(10-25-18)30-5-6-34-23(30)32/h3-4,7-12H,5-6H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.30	n/a	n/a	n/a	n/a	n/a	20
Jiangsu Hansoh Pharmaceutical Co., Ltd. US Patent					Assay Description Experimental Purpose: The purpose is to study the effect of the compounds on c-MET tyrosine kinase activity at the molecular level. IC50 values were ...				US Patent US9512121 (2016) BindingDB Entry DOI: 10.7270/Q2ST7NSV
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM259944 (US9512121, 28) Show SMILES Cn1cc(cn1)-c1ccc2nnc(Sc3ccc4ncc(N5CCOCC5)c(F)c4c3)n2c1 Show InChI InChI=1S/C23H20FN7OS/c1-29-13-16(11-26-29)15-2-5-21-27-28-23(31(21)14-15)33-17-3-4-19-18(10-17)22(24)20(12-25-19)30-6-8-32-9-7-30/h2-5,10-14H,6-9H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	20
Jiangsu Hansoh Pharmaceutical Co., Ltd. US Patent					Assay Description Experimental Purpose: The purpose is to study the effect of the compounds on c-MET tyrosine kinase activity at the molecular level. IC50 values were ...				US Patent US9512121 (2016) BindingDB Entry DOI: 10.7270/Q2ST7NSV
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM259928 (US9512121, 3) Show SMILES Cn1cc(cn1)-c1cc(F)c2nnc(Sc3ccc4ncc5OCCOc5c4c3)n2c1 Show InChI InChI=1S/C21H15FN6O2S/c1-27-10-13(8-24-27)12-6-16(22)20-25-26-21(28(20)11-12)31-14-2-3-17-15(7-14)19-18(9-23-17)29-4-5-30-19/h2-3,6-11H,4-5H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.90	n/a	n/a	n/a	n/a	n/a	20
Jiangsu Hansoh Pharmaceutical Co., Ltd. US Patent					Assay Description Experimental Purpose: The purpose is to study the effect of the compounds on c-MET tyrosine kinase activity at the molecular level. IC50 values were ...				US Patent US9512121 (2016) BindingDB Entry DOI: 10.7270/Q2ST7NSV
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM259960 (US9512121, 44) Show SMILES Cn1cc(cn1)-c1ccc2nnc(Sc3ccc4ncc(N5CCOCC5)c(Cl)c4c3)n2c1 Show InChI InChI=1S/C23H20ClN7OS/c1-29-13-16(11-26-29)15-2-5-21-27-28-23(31(21)14-15)33-17-3-4-19-18(10-17)22(24)20(12-25-19)30-6-8-32-9-7-30/h2-5,10-14H,6-9H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.40	n/a	n/a	n/a	n/a	n/a	20
Jiangsu Hansoh Pharmaceutical Co., Ltd. US Patent					Assay Description Experimental Purpose: The purpose is to study the effect of the compounds on c-MET tyrosine kinase activity at the molecular level. IC50 values were ...				US Patent US9512121 (2016) BindingDB Entry DOI: 10.7270/Q2ST7NSV
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM259952 (US9512121, 36) Show SMILES Cn1cc(cn1)-c1ccc2nnc(Sc3ccc4ncc(-c5cnn(C)c5)c(Cl)c4c3)n2c1 Show InChI InChI=1S/C23H17ClN8S/c1-30-11-15(8-26-30)14-3-6-21-28-29-23(32(21)13-14)33-17-4-5-20-18(7-17)22(24)19(10-25-20)16-9-27-31(2)12-16/h3-13H,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.60	n/a	n/a	n/a	n/a	n/a	20
Jiangsu Hansoh Pharmaceutical Co., Ltd. US Patent					Assay Description Experimental Purpose: The purpose is to study the effect of the compounds on c-MET tyrosine kinase activity at the molecular level. IC50 values were ...				US Patent US9512121 (2016) BindingDB Entry DOI: 10.7270/Q2ST7NSV
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM259927 (US9512121, 2) Show SMILES COc1ccnc2ccc(Sc3nnc4c(F)cc(cn34)-c3cnn(C)c3)cc12 Show InChI InChI=1S/C20H15FN6OS/c1-26-10-13(9-23-26)12-7-16(21)19-24-25-20(27(19)11-12)29-14-3-4-17-15(8-14)18(28-2)5-6-22-17/h3-11H,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.90	n/a	n/a	n/a	n/a	n/a	20
Jiangsu Hansoh Pharmaceutical Co., Ltd. US Patent					Assay Description Experimental Purpose: The purpose is to study the effect of the compounds on c-MET tyrosine kinase activity at the molecular level. IC50 values were ...				US Patent US9512121 (2016) BindingDB Entry DOI: 10.7270/Q2ST7NSV
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM259955 (US9512121, 39) Show SMILES COc1c(cnc2ccc(Sc3nnc4ccc(cn34)-c3cnn(C)c3)cc12)N1CCOCC1 Show InChI InChI=1S/C24H23N7O2S/c1-29-14-17(12-26-29)16-3-6-22-27-28-24(31(22)15-16)34-18-4-5-20-19(11-18)23(32-2)21(13-25-20)30-7-9-33-10-8-30/h3-6,11-15H,7-10H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	20
Jiangsu Hansoh Pharmaceutical Co., Ltd. US Patent					Assay Description Experimental Purpose: The purpose is to study the effect of the compounds on c-MET tyrosine kinase activity at the molecular level. IC50 values were ...				US Patent US9512121 (2016) BindingDB Entry DOI: 10.7270/Q2ST7NSV
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM259942 (US9512121, 26) Show SMILES Cn1cc(cn1)-c1ccc2nnc(Sc3ccc4ncc(-c5cnn(C)c5)c(OC(F)F)c4c3)n2c1 Show InChI InChI=1S/C24H18F2N8OS/c1-32-11-15(8-28-32)14-3-6-21-30-31-24(34(21)13-14)36-17-4-5-20-18(7-17)22(35-23(25)26)19(10-27-20)16-9-29-33(2)12-16/h3-13,23H,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.5	n/a	n/a	n/a	n/a	n/a	20
Jiangsu Hansoh Pharmaceutical Co., Ltd. US Patent					Assay Description Experimental Purpose: The purpose is to study the effect of the compounds on c-MET tyrosine kinase activity at the molecular level. IC50 values were ...				US Patent US9512121 (2016) BindingDB Entry DOI: 10.7270/Q2ST7NSV
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM259963 (US9512121, 47) Show SMILES COc1c(cnc2ccc(Sc3nnc4ccc(cn34)-c3cnn(C)c3)cc12)N1CCN(CC1)C(C)=O Show InChI InChI=1S/C26H26N8O2S/c1-17(35)32-8-10-33(11-9-32)23-14-27-22-6-5-20(12-21(22)25(23)36-3)37-26-30-29-24-7-4-18(16-34(24)26)19-13-28-31(2)15-19/h4-7,12-16H,8-11H2,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.70	n/a	n/a	n/a	n/a	n/a	20
Jiangsu Hansoh Pharmaceutical Co., Ltd. US Patent					Assay Description Experimental Purpose: The purpose is to study the effect of the compounds on c-MET tyrosine kinase activity at the molecular level. IC50 values were ...				US Patent US9512121 (2016) BindingDB Entry DOI: 10.7270/Q2ST7NSV
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM259945 (US9512121, 29) Show SMILES COc1ccnc2ccc(Sc3nnc4ccc(cn34)-c3cnn(C)c3)cc12 Show InChI InChI=1S/C20H16N6OS/c1-25-11-14(10-22-25)13-3-6-19-23-24-20(26(19)12-13)28-15-4-5-17-16(9-15)18(27-2)7-8-21-17/h3-12H,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7.10	n/a	n/a	n/a	n/a	n/a	20
Jiangsu Hansoh Pharmaceutical Co., Ltd. US Patent					Assay Description Experimental Purpose: The purpose is to study the effect of the compounds on c-MET tyrosine kinase activity at the molecular level. IC50 values were ...				US Patent US9512121 (2016) BindingDB Entry DOI: 10.7270/Q2ST7NSV
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50182518 (CHEMBL3819436 | US9512121, 19) Show SMILES Cn1cc(cn1)-c1cc(F)c2nnc(Sc3ccc4ncc5NC(=O)COc5c4c3)n2c1 Show InChI InChI=1S/C21H14FN7O2S/c1-28-8-12(6-24-28)11-4-15(22)20-26-27-21(29(20)9-11)32-13-2-3-16-14(5-13)19-17(7-23-16)25-18(30)10-31-19/h2-9H,10H2,1H3,(H,25,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	7.90	n/a	n/a	n/a	n/a	n/a	20
Jiangsu Hansoh Pharmaceutical Co., Ltd. US Patent					Assay Description Experimental Purpose: The purpose is to study the effect of the compounds on c-MET tyrosine kinase activity at the molecular level. IC50 values were ...				US Patent US9512121 (2016) BindingDB Entry DOI: 10.7270/Q2ST7NSV
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM259938 (US9512121, 17) Show SMILES Cn1cc(cn1)-c1ccc2nnc(Sc3ccc4ncc(N5CCOCC5)c(OCC5CC5)c4c3)n2c1 Show InChI InChI=1S/C27H27N7O2S/c1-32-15-20(13-29-32)19-4-7-25-30-31-27(34(25)16-19)37-21-5-6-23-22(12-21)26(36-17-18-2-3-18)24(14-28-23)33-8-10-35-11-9-33/h4-7,12-16,18H,2-3,8-11,17H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8.5	n/a	n/a	n/a	n/a	n/a	20
Jiangsu Hansoh Pharmaceutical Co., Ltd. US Patent					Assay Description Experimental Purpose: The purpose is to study the effect of the compounds on c-MET tyrosine kinase activity at the molecular level. IC50 values were ...				US Patent US9512121 (2016) BindingDB Entry DOI: 10.7270/Q2ST7NSV
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM259933 (US9512121, 10) Show SMILES CC(C)Oc1c(cnc2ccc(Sc3nnc4ccc(cn34)-c3cnn(C)c3)cc12)-c1cnn(C)c1 Show InChI InChI=1S/C26H24N8OS/c1-16(2)35-25-21-9-20(6-7-23(21)27-12-22(25)19-11-29-33(4)14-19)36-26-31-30-24-8-5-17(15-34(24)26)18-10-28-32(3)13-18/h5-16H,1-4H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8.60	n/a	n/a	n/a	n/a	n/a	20
Jiangsu Hansoh Pharmaceutical Co., Ltd. US Patent					Assay Description Experimental Purpose: The purpose is to study the effect of the compounds on c-MET tyrosine kinase activity at the molecular level. IC50 values were ...				US Patent US9512121 (2016) BindingDB Entry DOI: 10.7270/Q2ST7NSV
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50182519 (CHEMBL3818738 | US9512121, 18) Show SMILES Cn1cc(cn1)-c1ccc2nnc(Sc3ccc4ncc5NC(=O)COc5c4c3)n2c1 Show InChI InChI=1S/C21H15N7O2S/c1-27-9-13(7-23-27)12-2-5-18-25-26-21(28(18)10-12)31-14-3-4-16-15(6-14)20-17(8-22-16)24-19(29)11-30-20/h2-10H,11H2,1H3,(H,24,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	9.30	n/a	n/a	n/a	n/a	n/a	20
Jiangsu Hansoh Pharmaceutical Co., Ltd. US Patent					Assay Description Experimental Purpose: The purpose is to study the effect of the compounds on c-MET tyrosine kinase activity at the molecular level. IC50 values were ...				US Patent US9512121 (2016) BindingDB Entry DOI: 10.7270/Q2ST7NSV
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM259948 (US9512121, 32) Show SMILES Cn1cc(cn1)-c1ccc2nnc(Sc3ccc4nccc(Cl)c4c3)n2c1 Show InChI InChI=1S/C19H13ClN6S/c1-25-10-13(9-22-25)12-2-5-18-23-24-19(26(18)11-12)27-14-3-4-17-15(8-14)16(20)6-7-21-17/h2-11H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	20
Jiangsu Hansoh Pharmaceutical Co., Ltd. US Patent					Assay Description Experimental Purpose: The purpose is to study the effect of the compounds on c-MET tyrosine kinase activity at the molecular level. IC50 values were ...				US Patent US9512121 (2016) BindingDB Entry DOI: 10.7270/Q2ST7NSV
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM259958 (US9512121, 42) Show SMILES Cn1cc(cn1)-c1cc(F)c2nnc(Sc3ccc4ncc(N5CCOCC5)c(F)c4c3)n2c1 Show InChI InChI=1S/C23H19F2N7OS/c1-30-12-15(10-27-30)14-8-18(24)22-28-29-23(32(22)13-14)34-16-2-3-19-17(9-16)21(25)20(11-26-19)31-4-6-33-7-5-31/h2-3,8-13H,4-7H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10.7	n/a	n/a	n/a	n/a	n/a	20
Jiangsu Hansoh Pharmaceutical Co., Ltd. US Patent					Assay Description Experimental Purpose: The purpose is to study the effect of the compounds on c-MET tyrosine kinase activity at the molecular level. IC50 values were ...				US Patent US9512121 (2016) BindingDB Entry DOI: 10.7270/Q2ST7NSV
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM259929 (US9512121, 4) Show SMILES COc1c(cnc2ccc(Sc3nnc4c(F)cc(cn34)-c3cnn(C)c3)cc12)N1CCCC1=O Show InChI InChI=1S/C24H20FN7O2S/c1-30-12-15(10-27-30)14-8-18(25)23-28-29-24(32(23)13-14)35-16-5-6-19-17(9-16)22(34-2)20(11-26-19)31-7-3-4-21(31)33/h5-6,8-13H,3-4,7H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11.3	n/a	n/a	n/a	n/a	n/a	20
Jiangsu Hansoh Pharmaceutical Co., Ltd. US Patent					Assay Description Experimental Purpose: The purpose is to study the effect of the compounds on c-MET tyrosine kinase activity at the molecular level. IC50 values were ...				US Patent US9512121 (2016) BindingDB Entry DOI: 10.7270/Q2ST7NSV
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50182517 (CHEMBL3818928 | US9512121, 21) Show SMILES COCCN1C(=O)COc2c1cnc1ccc(Sc3nnc4c(F)cc(cn34)-c3cnn(C)c3)cc21 Show InChI InChI=1S/C24H20FN7O3S/c1-30-11-15(9-27-30)14-7-18(25)23-28-29-24(32(23)12-14)36-16-3-4-19-17(8-16)22-20(10-26-19)31(5-6-34-2)21(33)13-35-22/h3-4,7-12H,5-6,13H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	11.4	n/a	n/a	n/a	n/a	n/a	20
Jiangsu Hansoh Pharmaceutical Co., Ltd. US Patent					Assay Description Experimental Purpose: The purpose is to study the effect of the compounds on c-MET tyrosine kinase activity at the molecular level. IC50 values were ...				US Patent US9512121 (2016) BindingDB Entry DOI: 10.7270/Q2ST7NSV
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50182492 (CHEMBL3818387 | US9512121, 16) Show SMILES CN1C(=O)COc2c1cnc1ccc(Sc3nnc4ccc(cn34)-c3cnn(C)c3)cc21 Show InChI InChI=1S/C22H17N7O2S/c1-27-10-14(8-24-27)13-3-6-19-25-26-22(29(19)11-13)32-15-4-5-17-16(7-15)21-18(9-23-17)28(2)20(30)12-31-21/h3-11H,12H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	20
Jiangsu Hansoh Pharmaceutical Co., Ltd. US Patent					Assay Description Experimental Purpose: The purpose is to study the effect of the compounds on c-MET tyrosine kinase activity at the molecular level. IC50 values were ...				US Patent US9512121 (2016) BindingDB Entry DOI: 10.7270/Q2ST7NSV
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM259936 (US9512121, 14) Show SMILES Cn1cc(cn1)-c1cc(F)c2nnc(Sc3ccc4ncc5OCCCOc5c4c3)n2c1 Show InChI InChI=1S/C22H17FN6O2S/c1-28-11-14(9-25-28)13-7-17(23)21-26-27-22(29(21)12-13)32-15-3-4-18-16(8-15)20-19(10-24-18)30-5-2-6-31-20/h3-4,7-12H,2,5-6H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12.1	n/a	n/a	n/a	n/a	n/a	20
Jiangsu Hansoh Pharmaceutical Co., Ltd. US Patent					Assay Description Experimental Purpose: The purpose is to study the effect of the compounds on c-MET tyrosine kinase activity at the molecular level. IC50 values were ...				US Patent US9512121 (2016) BindingDB Entry DOI: 10.7270/Q2ST7NSV
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM259947 (US9512121, 31) Show SMILES Cn1cc(cn1)-c1ccc2nnc(Sc3ccc4ncc5OCCOc5c4c3)n2c1 Show InChI InChI=1S/C21H16N6O2S/c1-26-11-14(9-23-26)13-2-5-19-24-25-21(27(19)12-13)30-15-3-4-17-16(8-15)20-18(10-22-17)28-6-7-29-20/h2-5,8-12H,6-7H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12.1	n/a	n/a	n/a	n/a	n/a	20
Jiangsu Hansoh Pharmaceutical Co., Ltd. US Patent					Assay Description Experimental Purpose: The purpose is to study the effect of the compounds on c-MET tyrosine kinase activity at the molecular level. IC50 values were ...				US Patent US9512121 (2016) BindingDB Entry DOI: 10.7270/Q2ST7NSV
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM259939 (US9512121, 23) Show SMILES Cn1cc(cn1)-c1ccc2nnc(Sc3ccc4ncc5nc(sc5c4c3)C3CC3)n2c1 Show InChI InChI=1S/C23H17N7S2/c1-29-11-15(9-25-29)14-4-7-20-27-28-23(30(20)12-14)31-16-5-6-18-17(8-16)21-19(10-24-18)26-22(32-21)13-2-3-13/h4-13H,2-3H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13.9	n/a	n/a	n/a	n/a	n/a	20
Jiangsu Hansoh Pharmaceutical Co., Ltd. US Patent					Assay Description Experimental Purpose: The purpose is to study the effect of the compounds on c-MET tyrosine kinase activity at the molecular level. IC50 values were ...				US Patent US9512121 (2016) BindingDB Entry DOI: 10.7270/Q2ST7NSV
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM259940 (US9512121, 24) Show SMILES Cn1cc(cn1)-c1cc(F)c2nnc(Sc3ccc4ncc5nc(sc5c4c3)C3CC3)n2c1 Show InChI InChI=1S/C23H16FN7S2/c1-30-10-14(8-26-30)13-6-17(24)21-28-29-23(31(21)11-13)32-15-4-5-18-16(7-15)20-19(9-25-18)27-22(33-20)12-2-3-12/h4-12H,2-3H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15.3	n/a	n/a	n/a	n/a	n/a	20
Jiangsu Hansoh Pharmaceutical Co., Ltd. US Patent					Assay Description Experimental Purpose: The purpose is to study the effect of the compounds on c-MET tyrosine kinase activity at the molecular level. IC50 values were ...				US Patent US9512121 (2016) BindingDB Entry DOI: 10.7270/Q2ST7NSV
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM259932 (US9512121, 9) Show SMILES Cn1cc(cn1)-c1ccc2nnc(Sc3ccc4ncc(-c5cnn(C)c5)c(OCC(F)(F)F)c4c3)n2c1 Show InChI InChI=1S/C25H19F3N8OS/c1-34-11-16(8-30-34)15-3-6-22-32-33-24(36(22)13-15)38-18-4-5-21-19(7-18)23(37-14-25(26,27)28)20(10-29-21)17-9-31-35(2)12-17/h3-13H,14H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17.8	n/a	n/a	n/a	n/a	n/a	20
Jiangsu Hansoh Pharmaceutical Co., Ltd. US Patent					Assay Description Experimental Purpose: The purpose is to study the effect of the compounds on c-MET tyrosine kinase activity at the molecular level. IC50 values were ...				US Patent US9512121 (2016) BindingDB Entry DOI: 10.7270/Q2ST7NSV
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50182495 (CHEMBL3818361 | US9512121, 20) Show SMILES COCCN1C(=O)COc2c1cnc1ccc(Sc3nnc4ccc(cn34)-c3cnn(C)c3)cc21 Show InChI InChI=1S/C24H21N7O3S/c1-29-12-16(10-26-29)15-3-6-21-27-28-24(31(21)13-15)35-17-4-5-19-18(9-17)23-20(11-25-19)30(7-8-33-2)22(32)14-34-23/h3-6,9-13H,7-8,14H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	20.1	n/a	n/a	n/a	n/a	n/a	20
Jiangsu Hansoh Pharmaceutical Co., Ltd. US Patent					Assay Description Experimental Purpose: The purpose is to study the effect of the compounds on c-MET tyrosine kinase activity at the molecular level. IC50 values were ...				US Patent US9512121 (2016) BindingDB Entry DOI: 10.7270/Q2ST7NSV
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM259935 (US9512121, 12) Show SMILES Cn1cc(cn1)-c1ccc2nnc(Sc3ccc4ncc(-c5cnn(C)c5)c(OCC5CC5)c4c3)n2c1 Show InChI InChI=1S/C27H24N8OS/c1-33-13-19(10-29-33)18-5-8-25-31-32-27(35(25)15-18)37-21-6-7-24-22(9-21)26(36-16-17-3-4-17)23(12-28-24)20-11-30-34(2)14-20/h5-15,17H,3-4,16H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	28.3	n/a	n/a	n/a	n/a	n/a	20
Jiangsu Hansoh Pharmaceutical Co., Ltd. US Patent					Assay Description Experimental Purpose: The purpose is to study the effect of the compounds on c-MET tyrosine kinase activity at the molecular level. IC50 values were ...				US Patent US9512121 (2016) BindingDB Entry DOI: 10.7270/Q2ST7NSV
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM259949 (US9512121, 33) Show SMILES Cn1cc(cn1)-c1ccc2nnc(Sc3ccc4nccc(OCCO)c4c3)n2c1 Show InChI InChI=1S/C21H18N6O2S/c1-26-12-15(11-23-26)14-2-5-20-24-25-21(27(20)13-14)30-16-3-4-18-17(10-16)19(6-7-22-18)29-9-8-28/h2-7,10-13,28H,8-9H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	35.9	n/a	n/a	n/a	n/a	n/a	20
Jiangsu Hansoh Pharmaceutical Co., Ltd. US Patent					Assay Description Experimental Purpose: The purpose is to study the effect of the compounds on c-MET tyrosine kinase activity at the molecular level. IC50 values were ...				US Patent US9512121 (2016) BindingDB Entry DOI: 10.7270/Q2ST7NSV
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50182554 (CHEMBL3818731 | US9512121, 8) Show SMILES [H][C@]12CCCN1c1cnc3ccc(Sc4nnc5c(F)cc(cn45)-c4cnn(C)c4)cc3c1OC2 |r| Show InChI InChI=1S/C24H20FN7OS/c1-30-11-15(9-27-30)14-7-19(25)23-28-29-24(32(23)12-14)34-17-4-5-20-18(8-17)22-21(10-26-20)31-6-2-3-16(31)13-33-22/h4-5,7-12,16H,2-3,6,13H2,1H3/t16-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem	US Patent	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	20
Jiangsu Hansoh Pharmaceutical Co., Ltd. US Patent					Assay Description Experimental Purpose: The purpose is to study the effect of the compounds on c-MET tyrosine kinase activity at the molecular level. IC50 values were ...				US Patent US9512121 (2016) BindingDB Entry DOI: 10.7270/Q2ST7NSV
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM259937 (US9512121, 15) Show SMILES Cn1cc(cn1)-c1ccc2nnc(Sc3ccc4ncc5N(CCOc5c4c3)C(=O)C3CC3)n2c1 Show InChI InChI=1S/C25H21N7O2S/c1-30-13-17(11-27-30)16-4-7-22-28-29-25(32(22)14-16)35-18-5-6-20-19(10-18)23-21(12-26-20)31(8-9-34-23)24(33)15-2-3-15/h4-7,10-15H,2-3,8-9H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	42.5	n/a	n/a	n/a	n/a	n/a	20
Jiangsu Hansoh Pharmaceutical Co., Ltd. US Patent					Assay Description Experimental Purpose: The purpose is to study the effect of the compounds on c-MET tyrosine kinase activity at the molecular level. IC50 values were ...				US Patent US9512121 (2016) BindingDB Entry DOI: 10.7270/Q2ST7NSV
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM259962 (US9512121, 46) Show SMILES COc1c(cnc2ccc(Sc3nnc4ccc(cn34)-c3cnn(C)c3)cc12)-c1ccc2OCOc2c1 Show InChI InChI=1S/C27H20N6O3S/c1-32-13-18(11-29-32)17-4-8-25-30-31-27(33(25)14-17)37-19-5-6-22-20(10-19)26(34-2)21(12-28-22)16-3-7-23-24(9-16)36-15-35-23/h3-14H,15H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	20
Jiangsu Hansoh Pharmaceutical Co., Ltd. US Patent					Assay Description Experimental Purpose: The purpose is to study the effect of the compounds on c-MET tyrosine kinase activity at the molecular level. IC50 values were ...				US Patent US9512121 (2016) BindingDB Entry DOI: 10.7270/Q2ST7NSV
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM259941 (US9512121, 25) Show SMILES Cn1cc(cn1)-c1ccc2nnc(Sc3ccc4ncc5n(C)c(=O)oc5c4c3)n2c1 Show InChI InChI=1S/C21H15N7O2S/c1-26-10-13(8-23-26)12-3-6-18-24-25-20(28(18)11-12)31-14-4-5-16-15(7-14)19-17(9-22-16)27(2)21(29)30-19/h3-11H,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	56.6	n/a	n/a	n/a	n/a	n/a	20
Jiangsu Hansoh Pharmaceutical Co., Ltd. US Patent					Assay Description Experimental Purpose: The purpose is to study the effect of the compounds on c-MET tyrosine kinase activity at the molecular level. IC50 values were ...				US Patent US9512121 (2016) BindingDB Entry DOI: 10.7270/Q2ST7NSV
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM259946 (US9512121, 30) Show SMILES Cn1cc(cn1)-c1ccc2nnc(Sc3ccc4nccc(N5CCOCC5)c4c3)n2c1 Show InChI InChI=1S/C23H21N7OS/c1-28-14-17(13-25-28)16-2-5-22-26-27-23(30(22)15-16)32-18-3-4-20-19(12-18)21(6-7-24-20)29-8-10-31-11-9-29/h2-7,12-15H,8-11H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	122	n/a	n/a	n/a	n/a	n/a	20
Jiangsu Hansoh Pharmaceutical Co., Ltd. US Patent					Assay Description Experimental Purpose: The purpose is to study the effect of the compounds on c-MET tyrosine kinase activity at the molecular level. IC50 values were ...				US Patent US9512121 (2016) BindingDB Entry DOI: 10.7270/Q2ST7NSV
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50182528 (CHEMBL3818743 | US9512121, 7) Show SMILES [H][C@@]12CCCN1c1cnc3ccc(Sc4nnc5c(F)cc(cn45)-c4cnn(C)c4)cc3c1OC2 |r| Show InChI InChI=1S/C24H20FN7OS/c1-30-11-15(9-27-30)14-7-19(25)23-28-29-24(32(23)12-14)34-17-4-5-20-18(8-17)22-21(10-26-20)31-6-2-3-16(31)13-33-22/h4-5,7-12,16H,2-3,6,13H2,1H3/t16-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	123	n/a	n/a	n/a	n/a	n/a	20
Jiangsu Hansoh Pharmaceutical Co., Ltd. US Patent					Assay Description Experimental Purpose: The purpose is to study the effect of the compounds on c-MET tyrosine kinase activity at the molecular level. IC50 values were ...				US Patent US9512121 (2016) BindingDB Entry DOI: 10.7270/Q2ST7NSV
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM259951 (US9512121, 35) Show SMILES COCCN(C)c1ccnc2ccc(Sc3nnc4ccc(cn34)-c3cnn(C)c3)cc12 Show InChI InChI=1S/C23H23N7OS/c1-28(10-11-31-3)21-8-9-24-20-6-5-18(12-19(20)21)32-23-27-26-22-7-4-16(15-30(22)23)17-13-25-29(2)14-17/h4-9,12-15H,10-11H2,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	175	n/a	n/a	n/a	n/a	n/a	20
Jiangsu Hansoh Pharmaceutical Co., Ltd. US Patent					Assay Description Experimental Purpose: The purpose is to study the effect of the compounds on c-MET tyrosine kinase activity at the molecular level. IC50 values were ...				US Patent US9512121 (2016) BindingDB Entry DOI: 10.7270/Q2ST7NSV
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM259961 (US9512121, 45) Show SMILES COc1c(cnc2ccc(Sc3nnc4ccc(cn34)-c3cnn(C)c3)cc12)-c1c(C)noc1C |(2.85,-1.32,;4.19,-.55,;4.19,.99,;5.52,1.76,;5.52,3.3,;4.19,4.07,;2.85,3.3,;1.52,4.07,;.19,3.3,;.19,1.76,;-1.15,.99,;-1.15,-.55,;.1,-1.46,;-.38,-2.92,;-1.92,-2.92,;-2.95,-4.07,;-4.46,-3.75,;-4.93,-2.28,;-3.9,-1.14,;-2.39,-1.46,;-6.44,-1.96,;-7.68,-2.87,;-8.93,-1.96,;-8.45,-.5,;-9.22,.84,;-6.91,-.5,;1.52,.99,;2.85,1.76,;6.85,.99,;6.85,-.55,;5.52,-1.32,;8.32,-1.03,;9.22,.22,;8.32,1.46,;9.09,2.8,)| Show InChI InChI=1S/C25H21N7O2S/c1-14-23(15(2)34-30-14)20-11-26-21-7-6-18(9-19(21)24(20)33-4)35-25-29-28-22-8-5-16(13-32(22)25)17-10-27-31(3)12-17/h5-13H,1-4H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	211	n/a	n/a	n/a	n/a	n/a	20
Jiangsu Hansoh Pharmaceutical Co., Ltd. US Patent					Assay Description Experimental Purpose: The purpose is to study the effect of the compounds on c-MET tyrosine kinase activity at the molecular level. IC50 values were ...				US Patent US9512121 (2016) BindingDB Entry DOI: 10.7270/Q2ST7NSV
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM259934 (US9512121, 11) Show SMILES COc1c(cnc2ccc(Sc3nnc4ccc(cn34)-c3cnn(C)c3)cc12)N1CCOCC1=O Show InChI InChI=1S/C24H21N7O3S/c1-29-12-16(10-26-29)15-3-6-21-27-28-24(31(21)13-15)35-17-4-5-19-18(9-17)23(33-2)20(11-25-19)30-7-8-34-14-22(30)32/h3-6,9-13H,7-8,14H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	309	n/a	n/a	n/a	n/a	n/a	20
Jiangsu Hansoh Pharmaceutical Co., Ltd. US Patent					Assay Description Experimental Purpose: The purpose is to study the effect of the compounds on c-MET tyrosine kinase activity at the molecular level. IC50 values were ...				US Patent US9512121 (2016) BindingDB Entry DOI: 10.7270/Q2ST7NSV
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM259950 (US9512121, 34) Show SMILES CN(CCO)c1ccnc2ccc(Sc3nnc4ccc(cn34)-c3cnn(C)c3)cc12 Show InChI InChI=1S/C22H21N7OS/c1-27(9-10-30)20-7-8-23-19-5-4-17(11-18(19)20)31-22-26-25-21-6-3-15(14-29(21)22)16-12-24-28(2)13-16/h3-8,11-14,30H,9-10H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	440	n/a	n/a	n/a	n/a	n/a	20
Jiangsu Hansoh Pharmaceutical Co., Ltd. US Patent					Assay Description Experimental Purpose: The purpose is to study the effect of the compounds on c-MET tyrosine kinase activity at the molecular level. IC50 values were ...				US Patent US9512121 (2016) BindingDB Entry DOI: 10.7270/Q2ST7NSV
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM259959 (US9512121, 43) Show SMILES Cn1cc(cn1)-c1ccc2nnc(Sc3ccc4ncc(C(=O)N5CCOCC5)c(Cl)c4c3)n2c1 Show InChI InChI=1S/C24H20ClN7O2S/c1-30-13-16(11-27-30)15-2-5-21-28-29-24(32(21)14-15)35-17-3-4-20-18(10-17)22(25)19(12-26-20)23(33)31-6-8-34-9-7-31/h2-5,10-14H,6-9H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	462	n/a	n/a	n/a	n/a	n/a	20
Jiangsu Hansoh Pharmaceutical Co., Ltd. US Patent					Assay Description Experimental Purpose: The purpose is to study the effect of the compounds on c-MET tyrosine kinase activity at the molecular level. IC50 values were ...				US Patent US9512121 (2016) BindingDB Entry DOI: 10.7270/Q2ST7NSV
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM259954 (US9512121, 38) Show SMILES COc1cc(cn2c(Sc3ccc4ncc(-c5cnn(C)c5)c(OC)c4c3)nnc12)-c1cnn(C)c1 Show InChI InChI=1S/C25H22N8O2S/c1-31-12-16(9-27-31)15-7-22(34-3)24-29-30-25(33(24)14-15)36-18-5-6-21-19(8-18)23(35-4)20(11-26-21)17-10-28-32(2)13-17/h5-14H,1-4H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	485	n/a	n/a	n/a	n/a	n/a	20
Jiangsu Hansoh Pharmaceutical Co., Ltd. US Patent					Assay Description Experimental Purpose: The purpose is to study the effect of the compounds on c-MET tyrosine kinase activity at the molecular level. IC50 values were ...				US Patent US9512121 (2016) BindingDB Entry DOI: 10.7270/Q2ST7NSV
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM259943 (US9512121, 27) Show SMILES CN(C(=O)C1CC1)c1cn(C)c2ccc(Sc3nnc4ccc(cn34)-c3cnn(C)c3)cc2c1=O Show InChI InChI=1S/C25H23N7O2S/c1-29-14-21(31(3)24(34)15-4-5-15)23(33)19-10-18(7-8-20(19)29)35-25-28-27-22-9-6-16(13-32(22)25)17-11-26-30(2)12-17/h6-15H,4-5H2,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	608	n/a	n/a	n/a	n/a	n/a	20
Jiangsu Hansoh Pharmaceutical Co., Ltd. US Patent					Assay Description Experimental Purpose: The purpose is to study the effect of the compounds on c-MET tyrosine kinase activity at the molecular level. IC50 values were ...				US Patent US9512121 (2016) BindingDB Entry DOI: 10.7270/Q2ST7NSV
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50182494 (CHEMBL3817891 | US9512121, 13) Show SMILES CN1C(=O)COc2c1cnc1ccc(Sc3nnc4c(OC(F)F)cc(cn34)-c3cnn(C)c3)cc21 Show InChI InChI=1S/C23H17F2N7O3S/c1-30-9-13(7-27-30)12-5-18(35-22(24)25)21-28-29-23(32(21)10-12)36-14-3-4-16-15(6-14)20-17(8-26-16)31(2)19(33)11-34-20/h3-10,22H,11H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	20
Jiangsu Hansoh Pharmaceutical Co., Ltd. US Patent					Assay Description Experimental Purpose: The purpose is to study the effect of the compounds on c-MET tyrosine kinase activity at the molecular level. IC50 values were ...				US Patent US9512121 (2016) BindingDB Entry DOI: 10.7270/Q2ST7NSV
					More data for this Ligand-Target Pair