Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Dihydrofolate reductase (Escherichia coli) | BDBM50022831 (6,7-Dimethyl-pteridine-2,4-diamine | CHEMBL29143) | MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents | PubMed | 44 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pennsylvania State University Curated by ChEMBL | Assay Description Thermodynamic Dissociation Constant for compound-Tyr31-dihydrofolate reductase (DHFR) complex at pH 8 | J Med Chem 31: 129-37 (1988) BindingDB Entry DOI: 10.7270/Q2MP53VF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Escherichia coli) | BDBM50022831 (6,7-Dimethyl-pteridine-2,4-diamine | CHEMBL29143) | MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents | PubMed | 57 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pennsylvania State University Curated by ChEMBL | Assay Description Inhibition constant for Tyr31-dihydrofolate reductase (DHFR)-NADPH-Compound complex | J Med Chem 31: 129-37 (1988) BindingDB Entry DOI: 10.7270/Q2MP53VF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Escherichia coli) | BDBM18050 (2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...) | MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | 330 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pennsylvania State University Curated by ChEMBL | Assay Description Thermodynamic Dissociation Constant for compound-Tyr31-dihydrofolate reductase (DHFR) complex at pH 9.5 | J Med Chem 31: 129-37 (1988) BindingDB Entry DOI: 10.7270/Q2MP53VF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Escherichia coli) | BDBM18050 (2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...) | MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | 2.40E+3 | -32.1 | n/a | n/a | n/a | n/a | n/a | 5.5 | 25 |
Pennsylvania State University Curated by ChEMBL | Assay Description Thermodynamic Dissociation Constant for compound-Val31-dihydrofolate reductase (DHFR) complex at pH 7 | J Med Chem 31: 129-37 (1988) BindingDB Entry DOI: 10.7270/Q2MP53VF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Escherichia coli) | BDBM50022831 (6,7-Dimethyl-pteridine-2,4-diamine | CHEMBL29143) | MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents | PubMed | 9.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pennsylvania State University Curated by ChEMBL | Assay Description Dissociation constant at(Koff) Tyr-31 of dihydrofolate reductase (DHFR) | J Med Chem 31: 129-37 (1988) BindingDB Entry DOI: 10.7270/Q2MP53VF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Escherichia coli) | BDBM18050 (2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...) | MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | 1.70E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pennsylvania State University Curated by ChEMBL | Assay Description Thermodynamic Dissociation Constant for compound-Phe31-dihydrofolate reductase (DHFR) complex at pH 8.5 | J Med Chem 31: 129-37 (1988) BindingDB Entry DOI: 10.7270/Q2MP53VF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Escherichia coli) | BDBM50022831 (6,7-Dimethyl-pteridine-2,4-diamine | CHEMBL29143) | MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents | PubMed | n/a | n/a | n/a | n/a | n/a | 25 | n/a | n/a | n/a |
Pennsylvania State University Curated by ChEMBL | Assay Description Thermodynamic Dissociation Constant for compound-Val31-dihydrofolate reductase (DHFR) complex at pH 7 | J Med Chem 31: 129-37 (1988) BindingDB Entry DOI: 10.7270/Q2MP53VF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Escherichia coli) | BDBM18050 (2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...) | MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | n/a | 1.10E+3 | n/a | n/a | n/a | 9.5 | n/a |
Pennsylvania State University Curated by ChEMBL | Assay Description Thermodynamic Dissociation Constant for compound-Tyr31-dihydrofolate reductase (DHFR) complex at pH 6 | J Med Chem 31: 129-37 (1988) BindingDB Entry DOI: 10.7270/Q2MP53VF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Escherichia coli) | BDBM50422885 (CHEMBL2364573 | NADPH) | MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 490 | n/a | n/a | n/a | 8.5 | n/a |
Pennsylvania State University Curated by ChEMBL | Assay Description Association constant (Kon) at Phe-31 of dihydrofolate reductase (DHFR) | J Med Chem 31: 129-37 (1988) BindingDB Entry DOI: 10.7270/Q2MP53VF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Escherichia coli) | BDBM50367343 ((2S)-2-[[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methyl...) | MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase MCE KEGG MMDB PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 810 | n/a | n/a | n/a | 7.0 | n/a |
Pennsylvania State University Curated by ChEMBL | Assay Description Thermodynamic Dissociation Constant for compound-Val31-dihydrofolate reductase (DHFR) complex at pH 7 | J Med Chem 31: 129-37 (1988) BindingDB Entry DOI: 10.7270/Q2MP53VF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Escherichia coli) | BDBM50367343 ((2S)-2-[[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methyl...) | MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase MCE KEGG MMDB PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 4.40E+3 | n/a | n/a | n/a | 7.0 | n/a |
Pennsylvania State University Curated by ChEMBL | Assay Description Dissociation constant at(Koff) Tyr-31 of dihydrofolate reductase (DHFR) | J Med Chem 31: 129-37 (1988) BindingDB Entry DOI: 10.7270/Q2MP53VF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Escherichia coli) | BDBM18044 ((2S)-2-[(4-{[(2-amino-4-oxo-1,4,7,8-tetrahydropter...) | MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid PDB UniChem Similars | PubMed | n/a | n/a | n/a | 6.20E+3 | n/a | n/a | n/a | 8.5 | n/a |
Pennsylvania State University Curated by ChEMBL | Assay Description Thermodynamic Dissociation Constant for compound-Val31-dihydrofolate reductase (DHFR) complex at pH 7 | J Med Chem 31: 129-37 (1988) BindingDB Entry DOI: 10.7270/Q2MP53VF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Escherichia coli) | BDBM18050 (2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...) | MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | n/a | n/a | n/a | 12 | n/a | n/a | n/a |
Pennsylvania State University Curated by ChEMBL | Assay Description Thermodynamic Dissociation Constant for compound-Val31-dihydrofolate reductase (DHFR) complex at pH 8.5 | J Med Chem 31: 129-37 (1988) BindingDB Entry DOI: 10.7270/Q2MP53VF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Escherichia coli) | BDBM18044 ((2S)-2-[(4-{[(2-amino-4-oxo-1,4,7,8-tetrahydropter...) | MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid PDB UniChem Similars | PubMed | n/a | n/a | n/a | 2.60E+3 | n/a | n/a | n/a | 7.0 | n/a |
Pennsylvania State University Curated by ChEMBL | Assay Description Thermodynamic Dissociation Constant for compound-Val31-dihydrofolate reductase (DHFR) complex at pH 8.5 | J Med Chem 31: 129-37 (1988) BindingDB Entry DOI: 10.7270/Q2MP53VF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Escherichia coli) | BDBM50022831 (6,7-Dimethyl-pteridine-2,4-diamine | CHEMBL29143) | MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents | PubMed | n/a | n/a | n/a | n/a | n/a | n/a | 1.20E+7 | n/a | n/a |
Pennsylvania State University Curated by ChEMBL | Assay Description Association constant (Kon) at Phe-31 of dihydrofolate reductase (DHFR) | J Med Chem 31: 129-37 (1988) BindingDB Entry DOI: 10.7270/Q2MP53VF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Escherichia coli) | BDBM18050 (2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...) | MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | n/a | n/a | n/a | n/a | 1.10E+7 | n/a | n/a |
Pennsylvania State University Curated by ChEMBL | Assay Description Thermodynamic Dissociation Constant for compound-Val31-dihydrofolate reductase (DHFR) complex at pH 7 | J Med Chem 31: 129-37 (1988) BindingDB Entry DOI: 10.7270/Q2MP53VF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Escherichia coli) | BDBM50422885 (CHEMBL2364573 | NADPH) | MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 340 | n/a | n/a | n/a | 7.0 | n/a |
Pennsylvania State University Curated by ChEMBL | Assay Description Thermodynamic Dissociation Constant for compound-Val31-dihydrofolate reductase (DHFR) complex at pH 7 | J Med Chem 31: 129-37 (1988) BindingDB Entry DOI: 10.7270/Q2MP53VF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Escherichia coli) | BDBM18044 ((2S)-2-[(4-{[(2-amino-4-oxo-1,4,7,8-tetrahydropter...) | MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid PDB UniChem Similars | PubMed | n/a | n/a | n/a | 210 | n/a | n/a | n/a | 7.0 | n/a |
Pennsylvania State University Curated by ChEMBL | Assay Description Thermodynamic Dissociation Constant for compound-Val31-dihydrofolate reductase (DHFR) complex at pH 7 | J Med Chem 31: 129-37 (1988) BindingDB Entry DOI: 10.7270/Q2MP53VF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Escherichia coli) | BDBM18050 (2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...) | MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | n/a | 140 | n/a | n/a | n/a | 8.0 | n/a |
Pennsylvania State University Curated by ChEMBL | Assay Description Thermodynamic Dissociation Constant for compound-Val31-dihydrofolate reductase (DHFR) complex at pH 7 | J Med Chem 31: 129-37 (1988) BindingDB Entry DOI: 10.7270/Q2MP53VF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Escherichia coli) | BDBM18050 (2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...) | MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | n/a | 0.0960 | n/a | n/a | n/a | 8.0 | n/a |
Pennsylvania State University Curated by ChEMBL | Assay Description Association constant(Kon) at Tyr-31 of dihydrofolate reductase (DHFR) | J Med Chem 31: 129-37 (1988) BindingDB Entry DOI: 10.7270/Q2MP53VF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Escherichia coli) | BDBM18050 (2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...) | MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | n/a | 1.70E+3 | n/a | n/a | n/a | 9.5 | n/a |
Pennsylvania State University Curated by ChEMBL | Assay Description Thermodynamic Dissociation Constant for compound-Val31-dihydrofolate reductase (DHFR) complex at pH 7 | J Med Chem 31: 129-37 (1988) BindingDB Entry DOI: 10.7270/Q2MP53VF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Escherichia coli) | BDBM50022831 (6,7-Dimethyl-pteridine-2,4-diamine | CHEMBL29143) | MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents | PubMed | n/a | n/a | n/a | 1.60E+3 | n/a | n/a | n/a | 6.0 | n/a |
Pennsylvania State University Curated by ChEMBL | Assay Description Thermodynamic Dissociation Constant for compound-Phe31-dihydrofolate reductase (DHFR) complex at pH 8 | J Med Chem 31: 129-37 (1988) BindingDB Entry DOI: 10.7270/Q2MP53VF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Escherichia coli) | BDBM50022831 (6,7-Dimethyl-pteridine-2,4-diamine | CHEMBL29143) | MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents | PubMed | n/a | n/a | n/a | 3.90E+3 | n/a | n/a | n/a | 6.0 | n/a |
Pennsylvania State University Curated by ChEMBL | Assay Description Thermodynamic Dissociation Constant for compound-Phe31-dihydrofolate reductase (DHFR) complex at pH 6 | J Med Chem 31: 129-37 (1988) BindingDB Entry DOI: 10.7270/Q2MP53VF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Escherichia coli) | BDBM18050 (2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...) | MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | n/a | n/a | n/a | 26 | n/a | n/a | n/a |
Pennsylvania State University Curated by ChEMBL | Assay Description Binding constant(Ki) to dihydrofolate reductase (DHFR) Phe -31 was determined | J Med Chem 31: 129-37 (1988) BindingDB Entry DOI: 10.7270/Q2MP53VF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Escherichia coli) | BDBM18050 (2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...) | MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | n/a | 31 | n/a | n/a | n/a | 9.5 | n/a |
Pennsylvania State University Curated by ChEMBL | Assay Description Thermodynamic Dissociation Constant for compound-Val31-dihydrofolate reductase (DHFR) complex at pH 7 | J Med Chem 31: 129-37 (1988) BindingDB Entry DOI: 10.7270/Q2MP53VF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Escherichia coli) | BDBM18050 (2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...) | MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | n/a | 0.0230 | n/a | n/a | n/a | 6.0 | n/a |
Pennsylvania State University Curated by ChEMBL | Assay Description Thermodynamic Dissociation Constant for compound-Tyr31-dihydrofolate reductase (DHFR) complex at pH 6 | J Med Chem 31: 129-37 (1988) BindingDB Entry DOI: 10.7270/Q2MP53VF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Escherichia coli) | BDBM18044 ((2S)-2-[(4-{[(2-amino-4-oxo-1,4,7,8-tetrahydropter...) | MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid PDB UniChem Similars | PubMed | n/a | n/a | n/a | 240 | n/a | n/a | n/a | 8.5 | n/a |
Pennsylvania State University Curated by ChEMBL | Assay Description Dissociation constant at Val-31(Kon)of dihydrofolate reductase (DHFR) | J Med Chem 31: 129-37 (1988) BindingDB Entry DOI: 10.7270/Q2MP53VF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Escherichia coli) | BDBM50022831 (6,7-Dimethyl-pteridine-2,4-diamine | CHEMBL29143) | MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents | PubMed | n/a | n/a | n/a | n/a | n/a | n/a | 6.80E+6 | n/a | n/a |
Pennsylvania State University Curated by ChEMBL | Assay Description Thermodynamic Dissociation Constant for compound-Val31-dihydrofolate reductase (DHFR) complex at pH 7 | J Med Chem 31: 129-37 (1988) BindingDB Entry DOI: 10.7270/Q2MP53VF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Escherichia coli) | BDBM50422885 (CHEMBL2364573 | NADPH) | MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 400 | n/a | n/a | n/a | 8.5 | n/a |
Pennsylvania State University Curated by ChEMBL | Assay Description Thermodynamic Dissociation Constant for compound-Phe31-dihydrofolate reductase (DHFR) complex at pH 8.5 | J Med Chem 31: 129-37 (1988) BindingDB Entry DOI: 10.7270/Q2MP53VF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Escherichia coli) | BDBM18044 ((2S)-2-[(4-{[(2-amino-4-oxo-1,4,7,8-tetrahydropter...) | MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid PDB UniChem Similars | PubMed | n/a | n/a | n/a | 2.90E+3 | n/a | n/a | n/a | 8.5 | n/a |
Pennsylvania State University Curated by ChEMBL | Assay Description Thermodynamic Dissociation Constant for compound-Phe31-dihydrofolate reductase (DHFR) complex at pH 6 | J Med Chem 31: 129-37 (1988) BindingDB Entry DOI: 10.7270/Q2MP53VF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Escherichia coli) | BDBM18050 (2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...) | MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | n/a | n/a | n/a | n/a | 1.50E+5 | n/a | n/a |
Pennsylvania State University Curated by ChEMBL | Assay Description Thermodynamic Dissociation Constant for compound-Phe31-dihydrofolate reductase (DHFR) complex at pH 9.5 | J Med Chem 31: 129-37 (1988) BindingDB Entry DOI: 10.7270/Q2MP53VF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Escherichia coli) | BDBM50422885 (CHEMBL2364573 | NADPH) | MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 220 | n/a | n/a | n/a | 7.0 | n/a |
Pennsylvania State University Curated by ChEMBL | Assay Description Association constant(Kon) at Tyr-31 of dihydrofolate reductase (DHFR) | J Med Chem 31: 129-37 (1988) BindingDB Entry DOI: 10.7270/Q2MP53VF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Escherichia coli) | BDBM50022833 ((S)-2-{4-[(2-Amino-4-oxo-1,4,5,6,7,8-hexahydro-pte...) | MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | 300 | n/a | n/a | n/a | 7.0 | n/a |
Pennsylvania State University Curated by ChEMBL | Assay Description Thermodynamic Dissociation Constant for compound-Tyr31-dihydrofolate reductase (DHFR) complex at pH 8.5 | J Med Chem 31: 129-37 (1988) BindingDB Entry DOI: 10.7270/Q2MP53VF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Escherichia coli) | BDBM50022833 ((S)-2-{4-[(2-Amino-4-oxo-1,4,5,6,7,8-hexahydro-pte...) | MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | 60 | n/a | n/a | n/a | 7.0 | n/a |
Pennsylvania State University Curated by ChEMBL | Assay Description Thermodynamic Dissociation Constant for compound-Tyr31-dihydrofolate reductase (DHFR) complex at pH 7 | J Med Chem 31: 129-37 (1988) BindingDB Entry DOI: 10.7270/Q2MP53VF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Escherichia coli) | BDBM50422885 (CHEMBL2364573 | NADPH) | MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 380 | n/a | n/a | n/a | 7.0 | n/a |
Pennsylvania State University Curated by ChEMBL | Assay Description Association constant at Val-31(Kon) of dihydrofolate reductase (DHFR) | J Med Chem 31: 129-37 (1988) BindingDB Entry DOI: 10.7270/Q2MP53VF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Escherichia coli) | BDBM50022831 (6,7-Dimethyl-pteridine-2,4-diamine | CHEMBL29143) | MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents | PubMed | n/a | n/a | n/a | n/a | n/a | 35 | n/a | n/a | n/a |
Pennsylvania State University Curated by ChEMBL | Assay Description Binding constant(Ki) to dihydrofolate reductase (DHFR) Val -31 was determined | J Med Chem 31: 129-37 (1988) BindingDB Entry DOI: 10.7270/Q2MP53VF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Escherichia coli) | BDBM18050 (2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...) | MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | n/a | 84 | n/a | n/a | n/a | 8.0 | n/a |
Pennsylvania State University Curated by ChEMBL | Assay Description Dissociation constant(Koff) at Phe-31 of dihydrofolate reductase (DHFR) | J Med Chem 31: 129-37 (1988) BindingDB Entry DOI: 10.7270/Q2MP53VF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Escherichia coli) | BDBM18050 (2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...) | MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | n/a | n/a | n/a | 26 | n/a | n/a | n/a |
Pennsylvania State University Curated by ChEMBL | Assay Description Thermodynamic Dissociation Constant for compound-Val31-dihydrofolate reductase (DHFR) complex at pH 8 | J Med Chem 31: 129-37 (1988) BindingDB Entry DOI: 10.7270/Q2MP53VF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Escherichia coli) | BDBM18050 (2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...) | MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | n/a | n/a | n/a | n/a | 3.60E+7 | n/a | n/a |
Pennsylvania State University Curated by ChEMBL | Assay Description Thermodynamic Dissociation Constant for compound-Val31-dihydrofolate reductase (DHFR) complex at pH 6 | J Med Chem 31: 129-37 (1988) BindingDB Entry DOI: 10.7270/Q2MP53VF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Escherichia coli) | BDBM18050 (2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...) | MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | n/a | 2.30 | n/a | n/a | n/a | 6.0 | n/a |
Pennsylvania State University Curated by ChEMBL | Assay Description Thermodynamic Dissociation Constant for compound-Val31-dihydrofolate reductase (DHFR) complex at pH 7 | J Med Chem 31: 129-37 (1988) BindingDB Entry DOI: 10.7270/Q2MP53VF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Escherichia coli) | BDBM18050 (2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...) | MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | n/a | 3.20 | n/a | n/a | n/a | 6.0 | n/a |
Pennsylvania State University Curated by ChEMBL | Assay Description Thermodynamic Dissociation Constant for compound-Val31-dihydrofolate reductase (DHFR) complex at pH 7 | J Med Chem 31: 129-37 (1988) BindingDB Entry DOI: 10.7270/Q2MP53VF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Escherichia coli) | BDBM50422885 (CHEMBL2364573 | NADPH) | MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 300 | n/a | n/a | n/a | 8.5 | n/a |
Pennsylvania State University Curated by ChEMBL | Assay Description Thermodynamic Dissociation Constant for compound-Val31-dihydrofolate reductase (DHFR) complex at pH 7 | J Med Chem 31: 129-37 (1988) BindingDB Entry DOI: 10.7270/Q2MP53VF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Escherichia coli) | BDBM18044 ((2S)-2-[(4-{[(2-amino-4-oxo-1,4,7,8-tetrahydropter...) | MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid PDB UniChem Similars | PubMed | n/a | n/a | n/a | 6.60E+3 | n/a | n/a | n/a | 7.0 | 25 |
Pennsylvania State University Curated by ChEMBL | Assay Description Thermodynamic Dissociation Constant for compound-Val31-dihydrofolate reductase (DHFR) complex at pH 7 | J Med Chem 31: 129-37 (1988) BindingDB Entry DOI: 10.7270/Q2MP53VF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Escherichia coli) | BDBM50367343 ((2S)-2-[[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methyl...) | MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase MCE KEGG MMDB PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 4.80E+3 | n/a | n/a | n/a | 7.0 | 25 |
Pennsylvania State University Curated by ChEMBL | Assay Description Thermodynamic Dissociation Constant for compound-Val31-dihydrofolate reductase (DHFR) complex at pH 7 | J Med Chem 31: 129-37 (1988) BindingDB Entry DOI: 10.7270/Q2MP53VF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Escherichia coli) | BDBM50022833 ((S)-2-{4-[(2-Amino-4-oxo-1,4,5,6,7,8-hexahydro-pte...) | MMDB NCI pathway Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL KEGG MMDB PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | 300 | n/a | n/a | n/a | 7.0 | 25 |
Pennsylvania State University Curated by ChEMBL | Assay Description Thermodynamic Dissociation Constant for compound-Val31-dihydrofolate reductase (DHFR) complex at pH 7 | J Med Chem 31: 129-37 (1988) BindingDB Entry DOI: 10.7270/Q2MP53VF | |||||||||||
More data for this Ligand-Target Pair |