Compile Data Set for Download or QSAR

Found 24 hits Enz. Inhib. hit(s) with all data for entry = 50031016   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carboxypeptidase B2 (Homo sapiens (Human))	BDBM50305346 ((S)-2-(2-aminoethoxy)-3-(1-phenyl-1H-imidazol-4-yl...) Show SMILES NCCO[C@@H](Cc1cn(cn1)-c1ccccc1)C(O)=O |r| Show InChI InChI=1S/C14H17N3O3/c15-6-7-20-13(14(18)19)8-11-9-17(10-16-11)12-4-2-1-3-5-12/h1-5,9-10,13H,6-8,15H2,(H,18,19)/t13-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of active form of human recombinant TAFI assessed as substrate turnover every 15 seconds for 30 mins				Bioorg Med Chem Lett 20: 92-6 (2010) Article DOI: 10.1016/j.bmcl.2009.11.029 BindingDB Entry DOI: 10.7270/Q2J1038R
					More data for this Ligand-Target Pair
Carboxypeptidase B2 (Homo sapiens (Human))	BDBM50305347 ((S)-2-(2-aminoethoxy)-3-(1-(4-tert-butylphenyl)-1H...) Show SMILES CC(C)(C)c1ccc(cc1)-n1cnc(C[C@H](OCCN)C(O)=O)c1 |r| Show InChI InChI=1S/C18H25N3O3/c1-18(2,3)13-4-6-15(7-5-13)21-11-14(20-12-21)10-16(17(22)23)24-9-8-19/h4-7,11-12,16H,8-10,19H2,1-3H3,(H,22,23)/t16-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	5.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of active form of human recombinant TAFI assessed as substrate turnover every 15 seconds for 30 mins				Bioorg Med Chem Lett 20: 92-6 (2010) Article DOI: 10.1016/j.bmcl.2009.11.029 BindingDB Entry DOI: 10.7270/Q2J1038R
					More data for this Ligand-Target Pair
Carboxypeptidase B2 (Homo sapiens (Human))	BDBM50305351 ((S)-2-((R)-1-aminopropan-2-yloxy)-3-(1-(pyridin-2-...) Show SMILES C[C@H](CN)O[C@@H](Cc1cn(cn1)-c1ccccn1)C(O)=O |r| Show InChI InChI=1S/C14H18N4O3/c1-10(7-15)21-12(14(19)20)6-11-8-18(9-17-11)13-4-2-3-5-16-13/h2-5,8-10,12H,6-7,15H2,1H3,(H,19,20)/t10-,12+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	5.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of active form of human recombinant TAFI assessed as substrate turnover every 15 seconds for 30 mins				Bioorg Med Chem Lett 20: 92-6 (2010) Article DOI: 10.1016/j.bmcl.2009.11.029 BindingDB Entry DOI: 10.7270/Q2J1038R
					More data for this Ligand-Target Pair
Carboxypeptidase B2 (Homo sapiens (Human))	BDBM50305345 ((S)-2-(2-aminoethoxy)-3-(1-propyl-1H-imidazol-4-yl...) Show SMILES CCCn1cnc(C[C@H](OCCN)C(O)=O)c1 |r| Show InChI InChI=1S/C11H19N3O3/c1-2-4-14-7-9(13-8-14)6-10(11(15)16)17-5-3-12/h7-8,10H,2-6,12H2,1H3,(H,15,16)/t10-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	6.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of active form of human recombinant TAFI assessed as substrate turnover every 15 seconds for 30 mins				Bioorg Med Chem Lett 20: 92-6 (2010) Article DOI: 10.1016/j.bmcl.2009.11.029 BindingDB Entry DOI: 10.7270/Q2J1038R
					More data for this Ligand-Target Pair
Carboxypeptidase B2 (Homo sapiens (Human))	BDBM50305352 ((S)-2-((R)-1-aminopropan-2-yloxy)-3-(1-phenyl-1H-i...) Show SMILES C[C@H](CN)O[C@@H](Cc1cn(cn1)-c1ccccc1)C(O)=O |r| Show InChI InChI=1S/C15H19N3O3/c1-11(8-16)21-14(15(19)20)7-12-9-18(10-17-12)13-5-3-2-4-6-13/h2-6,9-11,14H,7-8,16H2,1H3,(H,19,20)/t11-,14+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	7.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of active form of human recombinant TAFI assessed as substrate turnover every 15 seconds for 30 mins				Bioorg Med Chem Lett 20: 92-6 (2010) Article DOI: 10.1016/j.bmcl.2009.11.029 BindingDB Entry DOI: 10.7270/Q2J1038R
					More data for this Ligand-Target Pair
Carboxypeptidase B2 (Homo sapiens (Human))	BDBM50305348 ((S)-2-(2-aminoethoxy)-3-(1-(2-cyclohexylethyl)-1H-...) Show SMILES NCCO[C@@H](Cc1cn(CCC2CCCCC2)cn1)C(O)=O |r| Show InChI InChI=1S/C16H27N3O3/c17-7-9-22-15(16(20)21)10-14-11-19(12-18-14)8-6-13-4-2-1-3-5-13/h11-13,15H,1-10,17H2,(H,20,21)/t15-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	8.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of active form of human recombinant TAFI assessed as substrate turnover every 15 seconds for 30 mins				Bioorg Med Chem Lett 20: 92-6 (2010) Article DOI: 10.1016/j.bmcl.2009.11.029 BindingDB Entry DOI: 10.7270/Q2J1038R
					More data for this Ligand-Target Pair
Carboxypeptidase B2 (Homo sapiens (Human))	BDBM50305349 ((+/-)-2-(2-aminoethoxy)-3-(1-butyl-1H-imidazol-4-y...) Show SMILES CCCCn1cnc(CC(OCCN)C(O)=O)c1 Show InChI InChI=1S/C12H21N3O3/c1-2-3-5-15-8-10(14-9-15)7-11(12(16)17)18-6-4-13/h8-9,11H,2-7,13H2,1H3,(H,16,17)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of active form of human recombinant TAFI assessed as substrate turnover every 15 seconds for 30 mins				Bioorg Med Chem Lett 20: 92-6 (2010) Article DOI: 10.1016/j.bmcl.2009.11.029 BindingDB Entry DOI: 10.7270/Q2J1038R
					More data for this Ligand-Target Pair
Carboxypeptidase B2 (Homo sapiens (Human))	BDBM50226610 ((2S)-5-AMINO-2-[(1-PROPYL-1H-IMIDAZOL-4-YL)METHYL]...) Show SMILES CCCn1cnc(C[C@H](CCCN)C(O)=O)c1 Show InChI InChI=1S/C12H21N3O2/c1-2-6-15-8-11(14-9-15)7-10(12(16)17)4-3-5-13/h8-10H,2-7,13H2,1H3,(H,16,17)/t10-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of active form of human recombinant TAFI assessed as substrate turnover every 15 seconds for 30 mins				Bioorg Med Chem Lett 20: 92-6 (2010) Article DOI: 10.1016/j.bmcl.2009.11.029 BindingDB Entry DOI: 10.7270/Q2J1038R
					More data for this Ligand-Target Pair
Carboxypeptidase B (Homo sapiens (Human))	BDBM50305348 ((S)-2-(2-aminoethoxy)-3-(1-(2-cyclohexylethyl)-1H-...) Show SMILES NCCO[C@@H](Cc1cn(CCC2CCCCC2)cn1)C(O)=O |r| Show InChI InChI=1S/C16H27N3O3/c17-7-9-22-15(16(20)21)10-14-11-19(12-18-14)8-6-13-4-2-1-3-5-13/h11-13,15H,1-10,17H2,(H,20,21)/t15-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human pancreatic carboxypeptidase B				Bioorg Med Chem Lett 20: 92-6 (2010) Article DOI: 10.1016/j.bmcl.2009.11.029 BindingDB Entry DOI: 10.7270/Q2J1038R
					More data for this Ligand-Target Pair
Carboxypeptidase B (Homo sapiens (Human))	BDBM50305346 ((S)-2-(2-aminoethoxy)-3-(1-phenyl-1H-imidazol-4-yl...) Show SMILES NCCO[C@@H](Cc1cn(cn1)-c1ccccc1)C(O)=O |r| Show InChI InChI=1S/C14H17N3O3/c15-6-7-20-13(14(18)19)8-11-9-17(10-16-11)12-4-2-1-3-5-12/h1-5,9-10,13H,6-8,15H2,(H,18,19)/t13-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human pancreatic carboxypeptidase B				Bioorg Med Chem Lett 20: 92-6 (2010) Article DOI: 10.1016/j.bmcl.2009.11.029 BindingDB Entry DOI: 10.7270/Q2J1038R
					More data for this Ligand-Target Pair
Carboxypeptidase B (Homo sapiens (Human))	BDBM50305347 ((S)-2-(2-aminoethoxy)-3-(1-(4-tert-butylphenyl)-1H...) Show SMILES CC(C)(C)c1ccc(cc1)-n1cnc(C[C@H](OCCN)C(O)=O)c1 |r| Show InChI InChI=1S/C18H25N3O3/c1-18(2,3)13-4-6-15(7-5-13)21-11-14(20-12-21)10-16(17(22)23)24-9-8-19/h4-7,11-12,16H,8-10,19H2,1-3H3,(H,22,23)/t16-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	49	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human pancreatic carboxypeptidase B				Bioorg Med Chem Lett 20: 92-6 (2010) Article DOI: 10.1016/j.bmcl.2009.11.029 BindingDB Entry DOI: 10.7270/Q2J1038R
					More data for this Ligand-Target Pair
Carboxypeptidase B2 (Homo sapiens (Human))	BDBM50305350 ((+/-)-2-(2-aminoethoxy)-3-(1-o-tolyl-1H-imidazol-4...) Show SMILES Cc1ccccc1-n1cnc(CC(OCCN)C(O)=O)c1 Show InChI InChI=1S/C15H19N3O3/c1-11-4-2-3-5-13(11)18-9-12(17-10-18)8-14(15(19)20)21-7-6-16/h2-5,9-10,14H,6-8,16H2,1H3,(H,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	65	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of active form of human recombinant TAFI assessed as substrate turnover every 15 seconds for 30 mins				Bioorg Med Chem Lett 20: 92-6 (2010) Article DOI: 10.1016/j.bmcl.2009.11.029 BindingDB Entry DOI: 10.7270/Q2J1038R
					More data for this Ligand-Target Pair
Carboxypeptidase B2 (Homo sapiens (Human))	BDBM50226606 ((S)-2-(2-aminoethylamino)-3-(1-propyl-1H-imidazol-...) Show SMILES CCCn1cnc(C[C@H](NCCN)C(O)=O)c1 Show InChI InChI=1S/C11H20N4O2/c1-2-5-15-7-9(14-8-15)6-10(11(16)17)13-4-3-12/h7-8,10,13H,2-6,12H2,1H3,(H,16,17)/t10-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of active form of human recombinant TAFI assessed as substrate turnover every 15 seconds for 30 mins				Bioorg Med Chem Lett 20: 92-6 (2010) Article DOI: 10.1016/j.bmcl.2009.11.029 BindingDB Entry DOI: 10.7270/Q2J1038R
					More data for this Ligand-Target Pair
Carboxypeptidase B (Homo sapiens (Human))	BDBM50226610 ((2S)-5-AMINO-2-[(1-PROPYL-1H-IMIDAZOL-4-YL)METHYL]...) Show SMILES CCCn1cnc(C[C@H](CCCN)C(O)=O)c1 Show InChI InChI=1S/C12H21N3O2/c1-2-6-15-8-11(14-9-15)7-10(12(16)17)4-3-5-13/h8-10H,2-7,13H2,1H3,(H,16,17)/t10-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	206	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human pancreatic carboxypeptidase B				Bioorg Med Chem Lett 20: 92-6 (2010) Article DOI: 10.1016/j.bmcl.2009.11.029 BindingDB Entry DOI: 10.7270/Q2J1038R
					More data for this Ligand-Target Pair
Carboxypeptidase B (Homo sapiens (Human))	BDBM50305345 ((S)-2-(2-aminoethoxy)-3-(1-propyl-1H-imidazol-4-yl...) Show SMILES CCCn1cnc(C[C@H](OCCN)C(O)=O)c1 |r| Show InChI InChI=1S/C11H19N3O3/c1-2-4-14-7-9(13-8-14)6-10(11(15)16)17-5-3-12/h7-8,10H,2-6,12H2,1H3,(H,15,16)/t10-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	238	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human pancreatic carboxypeptidase B				Bioorg Med Chem Lett 20: 92-6 (2010) Article DOI: 10.1016/j.bmcl.2009.11.029 BindingDB Entry DOI: 10.7270/Q2J1038R
					More data for this Ligand-Target Pair
Carboxypeptidase B (Homo sapiens (Human))	BDBM50305352 ((S)-2-((R)-1-aminopropan-2-yloxy)-3-(1-phenyl-1H-i...) Show SMILES C[C@H](CN)O[C@@H](Cc1cn(cn1)-c1ccccc1)C(O)=O |r| Show InChI InChI=1S/C15H19N3O3/c1-11(8-16)21-14(15(19)20)7-12-9-18(10-17-12)13-5-3-2-4-6-13/h2-6,9-11,14H,7-8,16H2,1H3,(H,19,20)/t11-,14+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	240	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human pancreatic carboxypeptidase B				Bioorg Med Chem Lett 20: 92-6 (2010) Article DOI: 10.1016/j.bmcl.2009.11.029 BindingDB Entry DOI: 10.7270/Q2J1038R
					More data for this Ligand-Target Pair
Carboxypeptidase B (Homo sapiens (Human))	BDBM50305351 ((S)-2-((R)-1-aminopropan-2-yloxy)-3-(1-(pyridin-2-...) Show SMILES C[C@H](CN)O[C@@H](Cc1cn(cn1)-c1ccccn1)C(O)=O |r| Show InChI InChI=1S/C14H18N4O3/c1-10(7-15)21-12(14(19)20)6-11-8-18(9-17-11)13-4-2-3-5-16-13/h2-5,8-10,12H,6-7,15H2,1H3,(H,19,20)/t10-,12+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	265	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human pancreatic carboxypeptidase B				Bioorg Med Chem Lett 20: 92-6 (2010) Article DOI: 10.1016/j.bmcl.2009.11.029 BindingDB Entry DOI: 10.7270/Q2J1038R
					More data for this Ligand-Target Pair
Carboxypeptidase B (Homo sapiens (Human))	BDBM50305349 ((+/-)-2-(2-aminoethoxy)-3-(1-butyl-1H-imidazol-4-y...) Show SMILES CCCCn1cnc(CC(OCCN)C(O)=O)c1 Show InChI InChI=1S/C12H21N3O3/c1-2-3-5-15-8-10(14-9-15)7-11(12(16)17)18-6-4-13/h8-9,11H,2-7,13H2,1H3,(H,16,17)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	360	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human pancreatic carboxypeptidase B				Bioorg Med Chem Lett 20: 92-6 (2010) Article DOI: 10.1016/j.bmcl.2009.11.029 BindingDB Entry DOI: 10.7270/Q2J1038R
					More data for this Ligand-Target Pair
Carboxypeptidase B2 (Homo sapiens (Human))	BDBM50305353 ((+/-)-2-(2-(methylamino)ethoxy)-3-(1-propyl-1H-imi...) Show SMILES CCCn1cnc(CC(OCCNC)C(O)=O)c1 Show InChI InChI=1S/C12H21N3O3/c1-3-5-15-8-10(14-9-15)7-11(12(16)17)18-6-4-13-2/h8-9,11,13H,3-7H2,1-2H3,(H,16,17)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	407	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of active form of human recombinant TAFI assessed as substrate turnover every 15 seconds for 30 mins				Bioorg Med Chem Lett 20: 92-6 (2010) Article DOI: 10.1016/j.bmcl.2009.11.029 BindingDB Entry DOI: 10.7270/Q2J1038R
					More data for this Ligand-Target Pair
Carboxypeptidase B2 (Homo sapiens (Human))	BDBM50305354 ((R)-2-(2-aminoethoxy)-3-(1-propyl-1H-imidazol-4-yl...) Show SMILES CCCn1cnc(C[C@@H](OCCN)C(O)=O)c1 |r| Show InChI InChI=1S/C11H19N3O3/c1-2-4-14-7-9(13-8-14)6-10(11(15)16)17-5-3-12/h7-8,10H,2-6,12H2,1H3,(H,15,16)/t10-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of active form of human recombinant TAFI assessed as substrate turnover every 15 seconds for 30 mins				Bioorg Med Chem Lett 20: 92-6 (2010) Article DOI: 10.1016/j.bmcl.2009.11.029 BindingDB Entry DOI: 10.7270/Q2J1038R
					More data for this Ligand-Target Pair
Carboxypeptidase B (Homo sapiens (Human))	BDBM50226606 ((S)-2-(2-aminoethylamino)-3-(1-propyl-1H-imidazol-...) Show SMILES CCCn1cnc(C[C@H](NCCN)C(O)=O)c1 Show InChI InChI=1S/C11H20N4O2/c1-2-5-15-7-9(14-8-15)6-10(11(16)17)13-4-3-12/h7-8,10,13H,2-6,12H2,1H3,(H,16,17)/t10-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.16E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human pancreatic carboxypeptidase B				Bioorg Med Chem Lett 20: 92-6 (2010) Article DOI: 10.1016/j.bmcl.2009.11.029 BindingDB Entry DOI: 10.7270/Q2J1038R
					More data for this Ligand-Target Pair
Carboxypeptidase B (Homo sapiens (Human))	BDBM50305350 ((+/-)-2-(2-aminoethoxy)-3-(1-o-tolyl-1H-imidazol-4...) Show SMILES Cc1ccccc1-n1cnc(CC(OCCN)C(O)=O)c1 Show InChI InChI=1S/C15H19N3O3/c1-11-4-2-3-5-13(11)18-9-12(17-10-18)8-14(15(19)20)21-7-6-16/h2-5,9-10,14H,6-8,16H2,1H3,(H,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.72E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human pancreatic carboxypeptidase B				Bioorg Med Chem Lett 20: 92-6 (2010) Article DOI: 10.1016/j.bmcl.2009.11.029 BindingDB Entry DOI: 10.7270/Q2J1038R
					More data for this Ligand-Target Pair
Carboxypeptidase B (Homo sapiens (Human))	BDBM50305354 ((R)-2-(2-aminoethoxy)-3-(1-propyl-1H-imidazol-4-yl...) Show SMILES CCCn1cnc(C[C@@H](OCCN)C(O)=O)c1 |r| Show InChI InChI=1S/C11H19N3O3/c1-2-4-14-7-9(13-8-14)6-10(11(15)16)17-5-3-12/h7-8,10H,2-6,12H2,1H3,(H,15,16)/t10-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human pancreatic carboxypeptidase B				Bioorg Med Chem Lett 20: 92-6 (2010) Article DOI: 10.1016/j.bmcl.2009.11.029 BindingDB Entry DOI: 10.7270/Q2J1038R
					More data for this Ligand-Target Pair
Carboxypeptidase B (Homo sapiens (Human))	BDBM50305353 ((+/-)-2-(2-(methylamino)ethoxy)-3-(1-propyl-1H-imi...) Show SMILES CCCn1cnc(CC(OCCNC)C(O)=O)c1 Show InChI InChI=1S/C12H21N3O3/c1-3-5-15-8-10(14-9-15)7-11(12(16)17)18-6-4-13-2/h8-9,11,13H,3-7H2,1-2H3,(H,16,17)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human pancreatic carboxypeptidase B				Bioorg Med Chem Lett 20: 92-6 (2010) Article DOI: 10.1016/j.bmcl.2009.11.029 BindingDB Entry DOI: 10.7270/Q2J1038R
					More data for this Ligand-Target Pair