Compile Data Set for Download or QSAR

Found 27 hits Enz. Inhib. hit(s) with all data for entry = 50044293   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase kinase 4 (Homo sapiens (Human))	BDBM50011536 (CHEMBL3262587 | US9592235, Example 184 | US9855269...) Show SMILES Nc1ncnc2ccc(nc12)-c1cccc(F)c1 Show InChI InChI=1S/C13H9FN4/c14-9-3-1-2-8(6-9)10-4-5-11-12(18-10)13(15)17-7-16-11/h1-7H,(H2,15,16,17)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Inc. Curated by ChEMBL					Assay Description Inhibition of human MAP4K4 using 5-FAM-LGRDKYKTLRQIRQ-COOH as substrate by Z'-LYTE assay				J Med Chem 57: 3484-93 (2014) Article DOI: 10.1021/jm500155b BindingDB Entry DOI: 10.7270/Q2M046ZR
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase kinase 4 (Homo sapiens (Human))	BDBM50011561 (CHEMBL3262580 | US9592235, Example 174 | US9855269...) Show SMILES Nc1ncnc2ccc(cc12)-c1cccc(F)c1 Show InChI InChI=1S/C14H10FN3/c15-11-3-1-2-9(6-11)10-4-5-13-12(7-10)14(16)18-8-17-13/h1-8H,(H2,16,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Inc. Curated by ChEMBL					Assay Description Inhibition of human MAP4K4 using 5-FAM-LGRDKYKTLRQIRQ-COOH as substrate by Z'-LYTE assay				J Med Chem 57: 3484-93 (2014) Article DOI: 10.1021/jm500155b BindingDB Entry DOI: 10.7270/Q2M046ZR
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase kinase 4 (Homo sapiens (Human))	BDBM50011560 (CHEMBL3262579 | US9592235, Example 187 | US9855269...) Show SMILES Nc1cc(F)cc(c1)-c1ccc2ncnc(N)c2c1 Show InChI InChI=1S/C14H11FN4/c15-10-3-9(4-11(16)6-10)8-1-2-13-12(5-8)14(17)19-7-18-13/h1-7H,16H2,(H2,17,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Inc. Curated by ChEMBL					Assay Description Inhibition of human MAP4K4 using 5-FAM-LGRDKYKTLRQIRQ-COOH as substrate by Z'-LYTE assay				J Med Chem 57: 3484-93 (2014) Article DOI: 10.1021/jm500155b BindingDB Entry DOI: 10.7270/Q2M046ZR
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase kinase 4 (Homo sapiens (Human))	BDBM50011564 (CHEMBL3262583 | MAP10 | US9592235, Example 158 | U...) Show SMILES Nc1ncnc2ccc(cc12)-c1cccc(Cl)c1 Show InChI InChI=1S/C14H10ClN3/c15-11-3-1-2-9(6-11)10-4-5-13-12(7-10)14(16)18-8-17-13/h1-8H,(H2,16,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	77	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Inc. Curated by ChEMBL					Assay Description Inhibition of human MAP4K4 using 5-FAM-LGRDKYKTLRQIRQ-COOH as substrate by Z'-LYTE assay				J Med Chem 57: 3484-93 (2014) Article DOI: 10.1021/jm500155b BindingDB Entry DOI: 10.7270/Q2M046ZR
					More data for this Ligand-Target Pair				3D Structure (crystal)
Mitogen-activated protein kinase kinase kinase kinase 4 (Homo sapiens (Human))	BDBM50011551 (CHEMBL3262570 | US9592235, Example 268 | US9855269...) Show SMILES Nc1ncnc2ccc(cc12)-c1ccccc1 Show InChI InChI=1S/C14H11N3/c15-14-12-8-11(10-4-2-1-3-5-10)6-7-13(12)16-9-17-14/h1-9H,(H2,15,16,17)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	121	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Inc. Curated by ChEMBL					Assay Description Inhibition of human MAP4K4 using 5-FAM-LGRDKYKTLRQIRQ-COOH as substrate by Z'-LYTE assay				J Med Chem 57: 3484-93 (2014) Article DOI: 10.1021/jm500155b BindingDB Entry DOI: 10.7270/Q2M046ZR
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase kinase 4 (Homo sapiens (Human))	BDBM50011568 (CHEMBL3262584 | US9592235, Example 186 | US9855269...) Show SMILES Nc1ncnc2ccc(cc12)-c1cc(F)cc(F)c1 Show InChI InChI=1S/C14H9F2N3/c15-10-3-9(4-11(16)6-10)8-1-2-13-12(5-8)14(17)19-7-18-13/h1-7H,(H2,17,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	132	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Inc. Curated by ChEMBL					Assay Description Inhibition of human MAP4K4 using 5-FAM-LGRDKYKTLRQIRQ-COOH as substrate by Z'-LYTE assay				J Med Chem 57: 3484-93 (2014) Article DOI: 10.1021/jm500155b BindingDB Entry DOI: 10.7270/Q2M046ZR
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase kinase 4 (Homo sapiens (Human))	BDBM50011550 (CHEMBL3262569) Show SMILES Nc1cccc(c1)-c1ccc2ncnc(N)c2c1 Show InChI InChI=1S/C14H12N4/c15-11-3-1-2-9(6-11)10-4-5-13-12(7-10)14(16)18-8-17-13/h1-8H,15H2,(H2,16,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	189	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Inc. Curated by ChEMBL					Assay Description Inhibition of human MAP4K4 using 5-FAM-LGRDKYKTLRQIRQ-COOH as substrate by Z'-LYTE assay				J Med Chem 57: 3484-93 (2014) Article DOI: 10.1021/jm500155b BindingDB Entry DOI: 10.7270/Q2M046ZR
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase kinase 4 (Homo sapiens (Human))	BDBM50011556 (CHEMBL3262575 | US9592235, Example 164 | US9855269...) Show SMILES Nc1ncnc2ccc(cc12)-c1cccc(c1)C#N Show InChI InChI=1S/C15H10N4/c16-8-10-2-1-3-11(6-10)12-4-5-14-13(7-12)15(17)19-9-18-14/h1-7,9H,(H2,17,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	225	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Inc. Curated by ChEMBL					Assay Description Inhibition of human MAP4K4 using 5-FAM-LGRDKYKTLRQIRQ-COOH as substrate by Z'-LYTE assay				J Med Chem 57: 3484-93 (2014) Article DOI: 10.1021/jm500155b BindingDB Entry DOI: 10.7270/Q2M046ZR
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase kinase 4 (Homo sapiens (Human))	BDBM50011562 (CHEMBL3262581 | US9592235, Example 163 | US9855269...) Show SMILES Nc1ncnc2ccc(cc12)-c1ccccc1F Show InChI InChI=1S/C14H10FN3/c15-12-4-2-1-3-10(12)9-5-6-13-11(7-9)14(16)18-8-17-13/h1-8H,(H2,16,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	297	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Inc. Curated by ChEMBL					Assay Description Inhibition of human MAP4K4 using 5-FAM-LGRDKYKTLRQIRQ-COOH as substrate by Z'-LYTE assay				J Med Chem 57: 3484-93 (2014) Article DOI: 10.1021/jm500155b BindingDB Entry DOI: 10.7270/Q2M046ZR
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase kinase 4 (Homo sapiens (Human))	BDBM50011553 (CHEMBL3262572 | US9592235, Example 167 | US9855269...) Show SMILES COc1cccc(c1)-c1ccc2ncnc(N)c2c1 Show InChI InChI=1S/C15H13N3O/c1-19-12-4-2-3-10(7-12)11-5-6-14-13(8-11)15(16)18-9-17-14/h2-9H,1H3,(H2,16,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Inc. Curated by ChEMBL					Assay Description Inhibition of human MAP4K4 using 5-FAM-LGRDKYKTLRQIRQ-COOH as substrate by Z'-LYTE assay				J Med Chem 57: 3484-93 (2014) Article DOI: 10.1021/jm500155b BindingDB Entry DOI: 10.7270/Q2M046ZR
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase kinase 4 (Homo sapiens (Human))	BDBM50011559 (CHEMBL3262578 | US9592235, Example 269 | US9855269...) Show SMILES Nc1ccc(F)c(c1)-c1ccc2ncnc(N)c2c1 Show InChI InChI=1S/C14H11FN4/c15-12-3-2-9(16)6-10(12)8-1-4-13-11(5-8)14(17)19-7-18-13/h1-7H,16H2,(H2,17,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	351	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Inc. Curated by ChEMBL					Assay Description Inhibition of human MAP4K4 using 5-FAM-LGRDKYKTLRQIRQ-COOH as substrate by Z'-LYTE assay				J Med Chem 57: 3484-93 (2014) Article DOI: 10.1021/jm500155b BindingDB Entry DOI: 10.7270/Q2M046ZR
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase kinase 4 (Homo sapiens (Human))	BDBM50011563 (CHEMBL3262582) Show SMILES Nc1ncnc2ccc(cc12)-c1ccc(F)cc1 Show InChI InChI=1S/C14H10FN3/c15-11-4-1-9(2-5-11)10-3-6-13-12(7-10)14(16)18-8-17-13/h1-8H,(H2,16,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	381	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Inc. Curated by ChEMBL					Assay Description Inhibition of human MAP4K4 using 5-FAM-LGRDKYKTLRQIRQ-COOH as substrate by Z'-LYTE assay				J Med Chem 57: 3484-93 (2014) Article DOI: 10.1021/jm500155b BindingDB Entry DOI: 10.7270/Q2M046ZR
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase kinase 4 (Homo sapiens (Human))	BDBM50011558 (CHEMBL3262577 | US9592235, Example 266 | US9855269...) Show SMILES Nc1cc(ccc1F)-c1ccc2ncnc(N)c2c1 Show InChI InChI=1S/C14H11FN4/c15-11-3-1-9(6-12(11)16)8-2-4-13-10(5-8)14(17)19-7-18-13/h1-7H,16H2,(H2,17,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	387	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Inc. Curated by ChEMBL					Assay Description Inhibition of human MAP4K4 using 5-FAM-LGRDKYKTLRQIRQ-COOH as substrate by Z'-LYTE assay				J Med Chem 57: 3484-93 (2014) Article DOI: 10.1021/jm500155b BindingDB Entry DOI: 10.7270/Q2M046ZR
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase kinase 4 (Homo sapiens (Human))	BDBM50011555 (CHEMBL3262574 | US9592235, Example 162 | US9855269...) Show SMILES Cc1cccc(c1)-c1ccc2ncnc(N)c2c1 Show InChI InChI=1S/C15H13N3/c1-10-3-2-4-11(7-10)12-5-6-14-13(8-12)15(16)18-9-17-14/h2-9H,1H3,(H2,16,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	423	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Inc. Curated by ChEMBL					Assay Description Inhibition of human MAP4K4 using 5-FAM-LGRDKYKTLRQIRQ-COOH as substrate by Z'-LYTE assay				J Med Chem 57: 3484-93 (2014) Article DOI: 10.1021/jm500155b BindingDB Entry DOI: 10.7270/Q2M046ZR
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase kinase 4 (Homo sapiens (Human))	BDBM50011552 (CHEMBL3262571 | US9592235, Example 168 | US9855269...) Show SMILES COc1ccccc1-c1ccc2ncnc(N)c2c1 Show InChI InChI=1S/C15H13N3O/c1-19-14-5-3-2-4-11(14)10-6-7-13-12(8-10)15(16)18-9-17-13/h2-9H,1H3,(H2,16,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	546	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Inc. Curated by ChEMBL					Assay Description Inhibition of human MAP4K4 using 5-FAM-LGRDKYKTLRQIRQ-COOH as substrate by Z'-LYTE assay				J Med Chem 57: 3484-93 (2014) Article DOI: 10.1021/jm500155b BindingDB Entry DOI: 10.7270/Q2M046ZR
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase kinase 4 (Homo sapiens (Human))	BDBM50011554 (CHEMBL3262573 | US9592235, Example 166 | US9855269...) Show SMILES COc1ccc(cc1)-c1ccc2ncnc(N)c2c1 Show InChI InChI=1S/C15H13N3O/c1-19-12-5-2-10(3-6-12)11-4-7-14-13(8-11)15(16)18-9-17-14/h2-9H,1H3,(H2,16,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	689	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Inc. Curated by ChEMBL					Assay Description Inhibition of human MAP4K4 using 5-FAM-LGRDKYKTLRQIRQ-COOH as substrate by Z'-LYTE assay				J Med Chem 57: 3484-93 (2014) Article DOI: 10.1021/jm500155b BindingDB Entry DOI: 10.7270/Q2M046ZR
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase kinase 4 (Homo sapiens (Human))	BDBM50011557 (CHEMBL3262576 | US9592235, Example 165 | US9855269...) Show SMILES Nc1ncnc2ccc(cc12)-c1ccc(cc1)C#N Show InChI InChI=1S/C15H10N4/c16-8-10-1-3-11(4-2-10)12-5-6-14-13(7-12)15(17)19-9-18-14/h1-7,9H,(H2,17,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Inc. Curated by ChEMBL					Assay Description Inhibition of human MAP4K4 using 5-FAM-LGRDKYKTLRQIRQ-COOH as substrate by Z'-LYTE assay				J Med Chem 57: 3484-93 (2014) Article DOI: 10.1021/jm500155b BindingDB Entry DOI: 10.7270/Q2M046ZR
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase kinase 4 (Homo sapiens (Human))	BDBM50011535 (CHEMBL3262586) Show SMILES Nc1ncnc2cnc(cc12)-c1cccc(F)c1 Show InChI InChI=1S/C13H9FN4/c14-9-3-1-2-8(4-9)11-5-10-12(6-16-11)17-7-18-13(10)15/h1-7H,(H2,15,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.12E+3	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Inc. Curated by ChEMBL					Assay Description Inhibition of human MAP4K4 using 5-FAM-LGRDKYKTLRQIRQ-COOH as substrate by Z'-LYTE assay				J Med Chem 57: 3484-93 (2014) Article DOI: 10.1021/jm500155b BindingDB Entry DOI: 10.7270/Q2M046ZR
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase kinase 4 (Homo sapiens (Human))	BDBM50011534 (CHEMBL3262585) Show SMILES Nc1ncnc2ncc(cc12)-c1cccc(Cl)c1 Show InChI InChI=1S/C13H9ClN4/c14-10-3-1-2-8(4-10)9-5-11-12(15)17-7-18-13(11)16-6-9/h1-7H,(H2,15,16,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.84E+3	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Inc. Curated by ChEMBL					Assay Description Inhibition of human MAP4K4 using 5-FAM-LGRDKYKTLRQIRQ-COOH as substrate by Z'-LYTE assay				J Med Chem 57: 3484-93 (2014) Article DOI: 10.1021/jm500155b BindingDB Entry DOI: 10.7270/Q2M046ZR
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase kinase 4 (Homo sapiens (Human))	BDBM50011540 (CHEMBL3262564) Show SMILES Nc1cccc(c1)-c1cccnc1N Show InChI InChI=1S/C11H11N3/c12-9-4-1-3-8(7-9)10-5-2-6-14-11(10)13/h1-7H,12H2,(H2,13,14)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	6.50E+4	n/a	n/a	n/a	n/a	n/a
Genentech Inc. Curated by ChEMBL					Assay Description Binding affinity to N-terminal His-tagged C-terminal Avi-tagged MAP4K4 (unknown origin) expressed in baculovirus expression system by surface plasmon...				J Med Chem 57: 3484-93 (2014) Article DOI: 10.1021/jm500155b BindingDB Entry DOI: 10.7270/Q2M046ZR
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase kinase 4 (Homo sapiens (Human))	BDBM50011539 (CHEMBL3262563) Show SMILES Cc1onc(N)c1-c1cccc(N)c1 Show InChI InChI=1S/C10H11N3O/c1-6-9(10(12)13-14-6)7-3-2-4-8(11)5-7/h2-5H,11H2,1H3,(H2,12,13)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	3.51E+5	n/a	n/a	n/a	n/a	n/a
Genentech Inc. Curated by ChEMBL					Assay Description Binding affinity to N-terminal His-tagged C-terminal Avi-tagged MAP4K4 (unknown origin) expressed in baculovirus expression system by surface plasmon...				J Med Chem 57: 3484-93 (2014) Article DOI: 10.1021/jm500155b BindingDB Entry DOI: 10.7270/Q2M046ZR
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase kinase 4 (Homo sapiens (Human))	BDBM50011537 (CHEMBL3262562) Show SMILES Nc1cccc(c1)-c1cnco1 Show InChI InChI=1S/C9H8N2O/c10-8-3-1-2-7(4-8)9-5-11-6-12-9/h1-6H,10H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	2.20E+5	n/a	n/a	n/a	n/a	n/a
Genentech Inc. Curated by ChEMBL					Assay Description Binding affinity to N-terminal His-tagged C-terminal Avi-tagged MAP4K4 (unknown origin) expressed in baculovirus expression system by surface plasmon...				J Med Chem 57: 3484-93 (2014) Article DOI: 10.1021/jm500155b BindingDB Entry DOI: 10.7270/Q2M046ZR
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase kinase 4 (Homo sapiens (Human))	BDBM50011550 (CHEMBL3262569) Show SMILES Nc1cccc(c1)-c1ccc2ncnc(N)c2c1 Show InChI InChI=1S/C14H12N4/c15-11-3-1-2-9(6-11)10-4-5-13-12(7-10)14(16)18-8-17-13/h1-8H,15H2,(H2,16,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	4.30E+3	n/a	n/a	n/a	n/a	n/a
Genentech Inc. Curated by ChEMBL					Assay Description Binding affinity to N-terminal His-tagged C-terminal Avi-tagged MAP4K4 (unknown origin) expressed in baculovirus expression system by surface plasmon...				J Med Chem 57: 3484-93 (2014) Article DOI: 10.1021/jm500155b BindingDB Entry DOI: 10.7270/Q2M046ZR
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase kinase 4 (Homo sapiens (Human))	BDBM50011547 (CHEMBL3262566) Show SMILES Nc1cccc(c1)-c1cnc(N)nc1 Show InChI InChI=1S/C10H10N4/c11-9-3-1-2-7(4-9)8-5-13-10(12)14-6-8/h1-6H,11H2,(H2,12,13,14)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	1.75E+5	n/a	n/a	n/a	n/a	n/a
Genentech Inc. Curated by ChEMBL					Assay Description Binding affinity to N-terminal His-tagged C-terminal Avi-tagged MAP4K4 (unknown origin) expressed in baculovirus expression system by surface plasmon...				J Med Chem 57: 3484-93 (2014) Article DOI: 10.1021/jm500155b BindingDB Entry DOI: 10.7270/Q2M046ZR
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase kinase 4 (Homo sapiens (Human))	BDBM50011548 (CHEMBL3262567) Show SMILES Cc1cc(cnc1N)-c1cccc(N)c1 Show InChI InChI=1S/C12H13N3/c1-8-5-10(7-15-12(8)14)9-3-2-4-11(13)6-9/h2-7H,13H2,1H3,(H2,14,15)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	6.80E+4	n/a	n/a	n/a	n/a	n/a
Genentech Inc. Curated by ChEMBL					Assay Description Binding affinity to N-terminal His-tagged C-terminal Avi-tagged MAP4K4 (unknown origin) expressed in baculovirus expression system by surface plasmon...				J Med Chem 57: 3484-93 (2014) Article DOI: 10.1021/jm500155b BindingDB Entry DOI: 10.7270/Q2M046ZR
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase kinase 4 (Homo sapiens (Human))	BDBM50011549 (CHEMBL3262568) Show SMILES Nc1cccc(c1)-c1ccc(N)nc1 Show InChI InChI=1S/C11H11N3/c12-10-3-1-2-8(6-10)9-4-5-11(13)14-7-9/h1-7H,12H2,(H2,13,14)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	5.10E+5	n/a	n/a	n/a	n/a	n/a
Genentech Inc. Curated by ChEMBL					Assay Description Binding affinity to N-terminal His-tagged C-terminal Avi-tagged MAP4K4 (unknown origin) expressed in baculovirus expression system by surface plasmon...				J Med Chem 57: 3484-93 (2014) Article DOI: 10.1021/jm500155b BindingDB Entry DOI: 10.7270/Q2M046ZR
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase kinase 4 (Homo sapiens (Human))	BDBM50011546 (CHEMBL3262565) Show SMILES CNc1ncc(cn1)-c1cccc(N)c1 Show InChI InChI=1S/C11H12N4/c1-13-11-14-6-9(7-15-11)8-3-2-4-10(12)5-8/h2-7H,12H2,1H3,(H,13,14,15)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	2.80E+4	n/a	n/a	n/a	n/a	n/a
Genentech Inc. Curated by ChEMBL					Assay Description Binding affinity to N-terminal His-tagged C-terminal Avi-tagged MAP4K4 (unknown origin) expressed in baculovirus expression system by surface plasmon...				J Med Chem 57: 3484-93 (2014) Article DOI: 10.1021/jm500155b BindingDB Entry DOI: 10.7270/Q2M046ZR
					More data for this Ligand-Target Pair