Compile Data Set for Download or QSAR

Found 46 hits Enz. Inhib. hit(s) with all data for entry = 50015261   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50104600 ((S)-3-{[(R)-1-(3-Piperidin-4-yl-propionyl)-piperid...) Show SMILES OC(=O)C[C@H](NC(=O)[C@@H]1CCCN(C1)C(=O)CCC1CCNCC1)c1cccnc1 Show InChI InChI=1S/C22H32N4O4/c27-20(6-5-16-7-10-23-11-8-16)26-12-2-4-18(15-26)22(30)25-19(13-21(28)29)17-3-1-9-24-14-17/h1,3,9,14,16,18-19,23H,2,4-8,10-13,15H2,(H,25,30)(H,28,29)/t18-,19+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.150	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of human Biotinylated Fg binding to immobilized Alpha II beta-3				Bioorg Med Chem Lett 14: 5227-32 (2004) Article DOI: 10.1016/j.bmcl.2004.06.061 BindingDB Entry DOI: 10.7270/Q2TH8M5Z
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50153559 (3-(2-Methyl-pyrimidin-5-yl)-4-[1-(3-5,6,7,8-tetrah...) Show SMILES Cc1ncc(cn1)C(CC1CCN(CC1)C(=O)CCc1ccc2CCCNc2n1)CC(O)=O Show InChI InChI=1S/C25H33N5O3/c1-17-27-15-21(16-28-17)20(14-24(32)33)13-18-8-11-30(12-9-18)23(31)7-6-22-5-4-19-3-2-10-26-25(19)29-22/h4-5,15-16,18,20H,2-3,6-14H2,1H3,(H,26,29)(H,32,33)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of human vitronectin binding to immobilized Alpha v beta-3				Bioorg Med Chem Lett 14: 5227-32 (2004) Article DOI: 10.1016/j.bmcl.2004.06.061 BindingDB Entry DOI: 10.7270/Q2TH8M5Z
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50153566 (3-Pyridin-3-yl-4-[1-(3-5,6,7,8-tetrahydro-[1,8]nap...) Show SMILES OC(=O)CC(CC1CCN(CC1)C(=O)CCc1ccc2CCCNc2n1)c1cccnc1 Show InChI InChI=1S/C25H32N4O3/c30-23(8-7-22-6-5-19-3-2-12-27-25(19)28-22)29-13-9-18(10-14-29)15-21(16-24(31)32)20-4-1-11-26-17-20/h1,4-6,11,17-18,21H,2-3,7-10,12-16H2,(H,27,28)(H,31,32)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of human vitronectin binding to immobilized Alpha v beta-3				Bioorg Med Chem Lett 14: 5227-32 (2004) Article DOI: 10.1016/j.bmcl.2004.06.061 BindingDB Entry DOI: 10.7270/Q2TH8M5Z
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50153554 (3-(3-Fluoro-phenyl)-4-[1-(3-5,6,7,8-tetrahydro-[1,...) Show SMILES OC(=O)CC(CC1CCN(CC1)C(=O)CCc1ccc2CCCNc2n1)c1cccc(F)c1 Show InChI InChI=1S/C26H32FN3O3/c27-22-5-1-3-20(16-22)21(17-25(32)33)15-18-10-13-30(14-11-18)24(31)9-8-23-7-6-19-4-2-12-28-26(19)29-23/h1,3,5-7,16,18,21H,2,4,8-15,17H2,(H,28,29)(H,32,33)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of human vitronectin binding to immobilized Alpha v beta-3				Bioorg Med Chem Lett 14: 5227-32 (2004) Article DOI: 10.1016/j.bmcl.2004.06.061 BindingDB Entry DOI: 10.7270/Q2TH8M5Z
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50153553 (3-Benzo[1,3]dioxol-5-yl-4-[1-(3-5,6,7,8-tetrahydro...) Show SMILES OC(=O)CC(CC1CCN(CC1)C(=O)CCc1ccc2CCCNc2n1)c1ccc2OCOc2c1 Show InChI InChI=1S/C27H33N3O5/c31-25(8-6-22-5-3-19-2-1-11-28-27(19)29-22)30-12-9-18(10-13-30)14-21(16-26(32)33)20-4-7-23-24(15-20)35-17-34-23/h3-5,7,15,18,21H,1-2,6,8-14,16-17H2,(H,28,29)(H,32,33)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of human vitronectin binding to immobilized Alpha v beta-3				Bioorg Med Chem Lett 14: 5227-32 (2004) Article DOI: 10.1016/j.bmcl.2004.06.061 BindingDB Entry DOI: 10.7270/Q2TH8M5Z
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50153555 (3-(2,4-Dimethoxy-pyrimidin-5-yl)-4-[1-(3-5,6,7,8-t...) Show SMILES COc1ncc(C(CC2CCN(CC2)C(=O)CCc2ccc3CCCNc3n2)CC(O)=O)c(OC)n1 Show InChI InChI=1S/C26H35N5O5/c1-35-25-21(16-28-26(30-25)36-2)19(15-23(33)34)14-17-9-12-31(13-10-17)22(32)8-7-20-6-5-18-4-3-11-27-24(18)29-20/h5-6,16-17,19H,3-4,7-15H2,1-2H3,(H,27,29)(H,33,34)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of human vitronectin binding to immobilized Alpha v beta-3				Bioorg Med Chem Lett 14: 5227-32 (2004) Article DOI: 10.1016/j.bmcl.2004.06.061 BindingDB Entry DOI: 10.7270/Q2TH8M5Z
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50153558 (3-Benzo[1,3]dioxol-5-yl-5-{1-[3-(5-hydroxy-1,4,5,6...) Show SMILES OC1CCC(Nc2cccc(c2)C(=O)N2CCC(CCC(CC(O)=O)c3ccc4OCOc4c3)CC2)=NC1 |c:39| Show InChI InChI=1S/C29H35N3O6/c33-24-7-9-27(30-17-24)31-23-3-1-2-22(14-23)29(36)32-12-10-19(11-13-32)4-5-21(16-28(34)35)20-6-8-25-26(15-20)38-18-37-25/h1-3,6,8,14-15,19,21,24,33H,4-5,7,9-13,16-18H2,(H,30,31)(H,34,35)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of human vitronectin binding to immobilized Alpha v beta-3				Bioorg Med Chem Lett 14: 5227-32 (2004) Article DOI: 10.1016/j.bmcl.2004.06.061 BindingDB Entry DOI: 10.7270/Q2TH8M5Z
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50153569 (3-Naphthalen-2-yl-4-[1-(3-5,6,7,8-tetrahydro-[1,8]...) Show SMILES OC(=O)CC(CC1CCN(CC1)C(=O)CCc1ccc2CCCNc2n1)c1ccc2ccccc2c1 Show InChI InChI=1S/C30H35N3O3/c34-28(12-11-27-10-9-23-6-3-15-31-30(23)32-27)33-16-13-21(14-17-33)18-26(20-29(35)36)25-8-7-22-4-1-2-5-24(22)19-25/h1-2,4-5,7-10,19,21,26H,3,6,11-18,20H2,(H,31,32)(H,35,36)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of human vitronectin binding to immobilized Alpha v beta-3				Bioorg Med Chem Lett 14: 5227-32 (2004) Article DOI: 10.1016/j.bmcl.2004.06.061 BindingDB Entry DOI: 10.7270/Q2TH8M5Z
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50153570 (3-Benzo[1,3]dioxol-5-yl-3-[1-(4-5,6,7,8-tetrahydro...) Show SMILES OC(=O)CC(C1CCN(CC1)C(=O)CCCc1ccc2CCCNc2n1)c1ccc2OCOc2c1 Show InChI InChI=1S/C27H33N3O5/c31-25(5-1-4-21-8-6-19-3-2-12-28-27(19)29-21)30-13-10-18(11-14-30)22(16-26(32)33)20-7-9-23-24(15-20)35-17-34-23/h6-9,15,18,22H,1-5,10-14,16-17H2,(H,28,29)(H,32,33)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of human vitronectin binding to immobilized Alpha v beta-3				Bioorg Med Chem Lett 14: 5227-32 (2004) Article DOI: 10.1016/j.bmcl.2004.06.061 BindingDB Entry DOI: 10.7270/Q2TH8M5Z
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50153573 (3-Quinolin-3-yl-3-{[1-(3-5,6,7,8-tetrahydro-[1,8]n...) Show SMILES OC(=O)CC(NC(=O)C1CCN(CC1)C(=O)CCc1ccc2CCCNc2n1)c1cnc2ccccc2c1 Show InChI InChI=1S/C29H33N5O4/c35-26(10-9-23-8-7-19-5-3-13-30-28(19)32-23)34-14-11-20(12-15-34)29(38)33-25(17-27(36)37)22-16-21-4-1-2-6-24(21)31-18-22/h1-2,4,6-8,16,18,20,25H,3,5,9-15,17H2,(H,30,32)(H,33,38)(H,36,37)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.60	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of human vitronectin binding to immobilized Alpha v beta-3				Bioorg Med Chem Lett 14: 5227-32 (2004) Article DOI: 10.1016/j.bmcl.2004.06.061 BindingDB Entry DOI: 10.7270/Q2TH8M5Z
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50153571 (3-({1-[4-(4,5-Dihydro-1H-imidazol-2-ylamino)-butyr...) Show SMILES OC(=O)CC(NC(=O)C1CCN(CC1)C(=O)CCCNC1=NCCN1)c1cnc2ccccc2c1 |t:21| Show InChI InChI=1S/C25H32N6O4/c32-22(6-3-9-26-25-27-10-11-28-25)31-12-7-17(8-13-31)24(35)30-21(15-23(33)34)19-14-18-4-1-2-5-20(18)29-16-19/h1-2,4-5,14,16-17,21H,3,6-13,15H2,(H,30,35)(H,33,34)(H2,26,27,28)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.80	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of human vitronectin binding to immobilized Alpha v beta-3				Bioorg Med Chem Lett 14: 5227-32 (2004) Article DOI: 10.1016/j.bmcl.2004.06.061 BindingDB Entry DOI: 10.7270/Q2TH8M5Z
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50153564 (3-({1-[3-(5-Hydroxy-1,4,5,6-tetrahydro-pyridin-2-y...) Show SMILES OC1CCC(Nc2cccc(c2)C(=O)N2CCC(CC2)C(=O)NC(CC(O)=O)c2cnc3ccccc3c2)=NC1 |c:41| Show InChI InChI=1S/C30H33N5O5/c36-24-8-9-27(32-18-24)33-23-6-3-5-21(15-23)30(40)35-12-10-19(11-13-35)29(39)34-26(16-28(37)38)22-14-20-4-1-2-7-25(20)31-17-22/h1-7,14-15,17,19,24,26,36H,8-13,16,18H2,(H,32,33)(H,34,39)(H,37,38)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.5	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of human vitronectin binding to immobilized Alpha v beta-3				Bioorg Med Chem Lett 14: 5227-32 (2004) Article DOI: 10.1016/j.bmcl.2004.06.061 BindingDB Entry DOI: 10.7270/Q2TH8M5Z
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50153572 (3-Benzo[1,3]dioxol-5-yl-3-({1-[3-(1,4,5,6-tetrahyd...) Show SMILES OC(=O)CC(NC(=O)C1CCN(CC1)C(=O)c1cccc(NC2=NCCCC2)c1)c1ccc2OCOc2c1 |t:23| Show InChI InChI=1S/C28H32N4O6/c33-26(34)16-22(19-7-8-23-24(15-19)38-17-37-23)31-27(35)18-9-12-32(13-10-18)28(36)20-4-3-5-21(14-20)30-25-6-1-2-11-29-25/h3-5,7-8,14-15,18,22H,1-2,6,9-13,16-17H2,(H,29,30)(H,31,35)(H,33,34)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	10.4	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of human vitronectin binding to immobilized Alpha v beta-3				Bioorg Med Chem Lett 14: 5227-32 (2004) Article DOI: 10.1016/j.bmcl.2004.06.061 BindingDB Entry DOI: 10.7270/Q2TH8M5Z
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50153561 (3-({1-[4-(4,5-Dihydro-1H-imidazol-2-ylamino)-butyr...) Show SMILES OC(=O)CC(NC(=O)C1CCN(CC1)C(=O)CCCNC1=NCCN1)c1cccnc1 |t:21| Show InChI InChI=1S/C21H30N6O4/c28-18(4-2-8-23-21-24-9-10-25-21)27-11-5-15(6-12-27)20(31)26-17(13-19(29)30)16-3-1-7-22-14-16/h1,3,7,14-15,17H,2,4-6,8-13H2,(H,26,31)(H,29,30)(H2,23,24,25)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of human vitronectin binding to immobilized Alpha v beta-3				Bioorg Med Chem Lett 14: 5227-32 (2004) Article DOI: 10.1016/j.bmcl.2004.06.061 BindingDB Entry DOI: 10.7270/Q2TH8M5Z
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50153561 (3-({1-[4-(4,5-Dihydro-1H-imidazol-2-ylamino)-butyr...) Show SMILES OC(=O)CC(NC(=O)C1CCN(CC1)C(=O)CCCNC1=NCCN1)c1cccnc1 |t:21| Show InChI InChI=1S/C21H30N6O4/c28-18(4-2-8-23-21-24-9-10-25-21)27-11-5-15(6-12-27)20(31)26-17(13-19(29)30)16-3-1-7-22-14-16/h1,3,7,14-15,17H,2,4-6,8-13H2,(H,26,31)(H,29,30)(H2,23,24,25)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of human vitronectin binding to immobilized Alpha v beta-3				Bioorg Med Chem Lett 14: 5227-32 (2004) Article DOI: 10.1016/j.bmcl.2004.06.061 BindingDB Entry DOI: 10.7270/Q2TH8M5Z
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50153563 (3-Benzo[1,3]dioxol-5-yl-4-[1-(4-5,6,7,8-tetrahydro...) Show SMILES OC(=O)CC(CC1CCN(CC1)C(=O)CCCc1ccc2CCCNc2n1)c1ccc2OCOc2c1 Show InChI InChI=1S/C28H35N3O5/c32-26(5-1-4-23-8-6-20-3-2-12-29-28(20)30-23)31-13-10-19(11-14-31)15-22(17-27(33)34)21-7-9-24-25(16-21)36-18-35-24/h6-9,16,19,22H,1-5,10-15,17-18H2,(H,29,30)(H,33,34)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20.6	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of human vitronectin binding to immobilized Alpha v beta-3				Bioorg Med Chem Lett 14: 5227-32 (2004) Article DOI: 10.1016/j.bmcl.2004.06.061 BindingDB Entry DOI: 10.7270/Q2TH8M5Z
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50153567 (3-Benzo[1,3]dioxol-5-yl-3-{[1-(3-5,6,7,8-tetrahydr...) Show SMILES OC(=O)CC(NC(=O)C1CCN(CC1)C(=O)CCc1ccc2CCCNc2n1)c1ccc2OCOc2c1 Show InChI InChI=1S/C27H32N4O6/c32-24(8-6-20-5-3-17-2-1-11-28-26(17)29-20)31-12-9-18(10-13-31)27(35)30-21(15-25(33)34)19-4-7-22-23(14-19)37-16-36-22/h3-5,7,14,18,21H,1-2,6,8-13,15-16H2,(H,28,29)(H,30,35)(H,33,34)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	21.7	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of human vitronectin binding to immobilized Alpha v beta-3				Bioorg Med Chem Lett 14: 5227-32 (2004) Article DOI: 10.1016/j.bmcl.2004.06.061 BindingDB Entry DOI: 10.7270/Q2TH8M5Z
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50153568 (3-Benzo[1,3]dioxol-5-yl-3-({1-[3-(N''-pyridin-4-yl...) Show SMILES NC(NCc1ccncc1)=Nc1cccc(c1)C(=O)N1CCC(CC1)C(=O)NC(CC(O)=O)c1ccc2OCOc2c1 |w:10.11| Show InChI InChI=1S/C30H32N6O6/c31-30(33-17-19-6-10-32-11-7-19)34-23-3-1-2-22(14-23)29(40)36-12-8-20(9-13-36)28(39)35-24(16-27(37)38)21-4-5-25-26(15-21)42-18-41-25/h1-7,10-11,14-15,20,24H,8-9,12-13,16-18H2,(H,35,39)(H,37,38)(H3,31,33,34)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	25.3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of human vitronectin binding to immobilized Alpha v beta-3				Bioorg Med Chem Lett 14: 5227-32 (2004) Article DOI: 10.1016/j.bmcl.2004.06.061 BindingDB Entry DOI: 10.7270/Q2TH8M5Z
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50153562 (3-Benzo[1,3]dioxol-5-yl-3-[1-(3-5,6,7,8-tetrahydro...) Show SMILES OC(=O)CC(C1CCN(CC1)C(=O)CCc1ccc2CCCNc2n1)c1ccc2OCOc2c1 Show InChI InChI=1S/C26H31N3O5/c30-24(8-6-20-5-3-18-2-1-11-27-26(18)28-20)29-12-9-17(10-13-29)21(15-25(31)32)19-4-7-22-23(14-19)34-16-33-22/h3-5,7,14,17,21H,1-2,6,8-13,15-16H2,(H,27,28)(H,31,32)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	28.1	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of human vitronectin binding to immobilized Alpha v beta-3				Bioorg Med Chem Lett 14: 5227-32 (2004) Article DOI: 10.1016/j.bmcl.2004.06.061 BindingDB Entry DOI: 10.7270/Q2TH8M5Z
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50153568 (3-Benzo[1,3]dioxol-5-yl-3-({1-[3-(N''-pyridin-4-yl...) Show SMILES NC(NCc1ccncc1)=Nc1cccc(c1)C(=O)N1CCC(CC1)C(=O)NC(CC(O)=O)c1ccc2OCOc2c1 |w:10.11| Show InChI InChI=1S/C30H32N6O6/c31-30(33-17-19-6-10-32-11-7-19)34-23-3-1-2-22(14-23)29(40)36-12-8-20(9-13-36)28(39)35-24(16-27(37)38)21-4-5-25-26(15-21)42-18-41-25/h1-7,10-11,14-15,20,24H,8-9,12-13,16-18H2,(H,35,39)(H,37,38)(H3,31,33,34)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	56.4	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of human Biotinylated Fg binding to immobilized Alpha II beta-3				Bioorg Med Chem Lett 14: 5227-32 (2004) Article DOI: 10.1016/j.bmcl.2004.06.061 BindingDB Entry DOI: 10.7270/Q2TH8M5Z
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50153565 (3-Benzo[1,3]dioxol-5-yl-5-[1-(2-5,6,7,8-tetrahydro...) Show SMILES OC(=O)CC(CCC1CCN(CC1)C(=O)Cc1ccc2CCCNc2n1)c1ccc2OCOc2c1 Show InChI InChI=1S/C27H33N3O5/c31-25(16-22-7-5-19-2-1-11-28-27(19)29-22)30-12-9-18(10-13-30)3-4-21(15-26(32)33)20-6-8-23-24(14-20)35-17-34-23/h5-8,14,18,21H,1-4,9-13,15-17H2,(H,28,29)(H,32,33)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	75	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of human vitronectin binding to immobilized Alpha v beta-3				Bioorg Med Chem Lett 14: 5227-32 (2004) Article DOI: 10.1016/j.bmcl.2004.06.061 BindingDB Entry DOI: 10.7270/Q2TH8M5Z
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50153571 (3-({1-[4-(4,5-Dihydro-1H-imidazol-2-ylamino)-butyr...) Show SMILES OC(=O)CC(NC(=O)C1CCN(CC1)C(=O)CCCNC1=NCCN1)c1cnc2ccccc2c1 |t:21| Show InChI InChI=1S/C25H32N6O4/c32-22(6-3-9-26-25-27-10-11-28-25)31-12-7-17(8-13-31)24(35)30-21(15-23(33)34)19-14-18-4-1-2-5-20(18)29-16-19/h1-2,4-5,14,16-17,21H,3,6-13,15H2,(H,30,35)(H,33,34)(H2,26,27,28)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	79.3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of human Biotinylated Fg binding to immobilized Alpha II beta-3				Bioorg Med Chem Lett 14: 5227-32 (2004) Article DOI: 10.1016/j.bmcl.2004.06.061 BindingDB Entry DOI: 10.7270/Q2TH8M5Z
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50153557 (3-Benzo[1,3]dioxol-5-yl-5-[1-(3-5,6,7,8-tetrahydro...) Show SMILES OC(=O)CC(CCC1CCN(CC1)C(=O)CCc1ccc2CCCNc2n1)c1ccc2OCOc2c1 Show InChI InChI=1S/C28H35N3O5/c32-26(10-8-23-7-5-20-2-1-13-29-28(20)30-23)31-14-11-19(12-15-31)3-4-22(17-27(33)34)21-6-9-24-25(16-21)36-18-35-24/h5-7,9,16,19,22H,1-4,8,10-15,17-18H2,(H,29,30)(H,33,34)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	142	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of human vitronectin binding to immobilized Alpha v beta-3				Bioorg Med Chem Lett 14: 5227-32 (2004) Article DOI: 10.1016/j.bmcl.2004.06.061 BindingDB Entry DOI: 10.7270/Q2TH8M5Z
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50153564 (3-({1-[3-(5-Hydroxy-1,4,5,6-tetrahydro-pyridin-2-y...) Show SMILES OC1CCC(Nc2cccc(c2)C(=O)N2CCC(CC2)C(=O)NC(CC(O)=O)c2cnc3ccccc3c2)=NC1 |c:41| Show InChI InChI=1S/C30H33N5O5/c36-24-8-9-27(32-18-24)33-23-6-3-5-21(15-23)30(40)35-12-10-19(11-13-35)29(39)34-26(16-28(37)38)22-14-20-4-1-2-7-25(20)31-17-22/h1-7,14-15,17,19,24,26,36H,8-13,16,18H2,(H,32,33)(H,34,39)(H,37,38)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	177	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of human Biotinylated Fg binding to immobilized Alpha II beta-3				Bioorg Med Chem Lett 14: 5227-32 (2004) Article DOI: 10.1016/j.bmcl.2004.06.061 BindingDB Entry DOI: 10.7270/Q2TH8M5Z
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50153572 (3-Benzo[1,3]dioxol-5-yl-3-({1-[3-(1,4,5,6-tetrahyd...) Show SMILES OC(=O)CC(NC(=O)C1CCN(CC1)C(=O)c1cccc(NC2=NCCCC2)c1)c1ccc2OCOc2c1 |t:23| Show InChI InChI=1S/C28H32N4O6/c33-26(34)16-22(19-7-8-23-24(15-19)38-17-37-23)31-27(35)18-9-12-32(13-10-18)28(36)20-4-3-5-21(14-20)30-25-6-1-2-11-29-25/h3-5,7-8,14-15,18,22H,1-2,6,9-13,16-17H2,(H,29,30)(H,31,35)(H,33,34)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	209	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of human Biotinylated Fg binding to immobilized Alpha II beta-3				Bioorg Med Chem Lett 14: 5227-32 (2004) Article DOI: 10.1016/j.bmcl.2004.06.061 BindingDB Entry DOI: 10.7270/Q2TH8M5Z
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50153560 (3-Benzo[1,3]dioxol-5-yl-5-{1-[4-(pyridin-2-ylamino...) Show SMILES OC(=O)CC(CCC1CCN(CC1)C(=O)CCCNc1ccccn1)c1ccc2OCOc2c1 Show InChI InChI=1S/C26H33N3O5/c30-25(5-3-13-28-24-4-1-2-12-27-24)29-14-10-19(11-15-29)6-7-21(17-26(31)32)20-8-9-22-23(16-20)34-18-33-22/h1-2,4,8-9,12,16,19,21H,3,5-7,10-11,13-15,17-18H2,(H,27,28)(H,31,32)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	233	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of human vitronectin binding to immobilized Alpha v beta-3				Bioorg Med Chem Lett 14: 5227-32 (2004) Article DOI: 10.1016/j.bmcl.2004.06.061 BindingDB Entry DOI: 10.7270/Q2TH8M5Z
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50153556 (3-Benzo[1,3]dioxol-5-yl-3-[1-(2-5,6,7,8-tetrahydro...) Show SMILES OC(=O)CC(C1CCN(CC1)C(=O)Cc1ccc2CCCNc2n1)c1ccc2OCOc2c1 Show InChI InChI=1S/C25H29N3O5/c29-23(13-19-5-3-17-2-1-9-26-25(17)27-19)28-10-7-16(8-11-28)20(14-24(30)31)18-4-6-21-22(12-18)33-15-32-21/h3-6,12,16,20H,1-2,7-11,13-15H2,(H,26,27)(H,30,31)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	281	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of human vitronectin binding to immobilized Alpha v beta-3 (N=1)				Bioorg Med Chem Lett 14: 5227-32 (2004) Article DOI: 10.1016/j.bmcl.2004.06.061 BindingDB Entry DOI: 10.7270/Q2TH8M5Z
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50153559 (3-(2-Methyl-pyrimidin-5-yl)-4-[1-(3-5,6,7,8-tetrah...) Show SMILES Cc1ncc(cn1)C(CC1CCN(CC1)C(=O)CCc1ccc2CCCNc2n1)CC(O)=O Show InChI InChI=1S/C25H33N5O3/c1-17-27-15-21(16-28-17)20(14-24(32)33)13-18-8-11-30(12-9-18)23(31)7-6-22-5-4-19-3-2-10-26-25(19)29-22/h4-5,15-16,18,20H,2-3,6-14H2,1H3,(H,26,29)(H,32,33)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	965	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of human Biotinylated Fg binding to immobilized Alpha II beta-3				Bioorg Med Chem Lett 14: 5227-32 (2004) Article DOI: 10.1016/j.bmcl.2004.06.061 BindingDB Entry DOI: 10.7270/Q2TH8M5Z
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50153555 (3-(2,4-Dimethoxy-pyrimidin-5-yl)-4-[1-(3-5,6,7,8-t...) Show SMILES COc1ncc(C(CC2CCN(CC2)C(=O)CCc2ccc3CCCNc3n2)CC(O)=O)c(OC)n1 Show InChI InChI=1S/C26H35N5O5/c1-35-25-21(16-28-26(30-25)36-2)19(15-23(33)34)14-17-9-12-31(13-10-17)22(32)8-7-20-6-5-18-4-3-11-27-24(18)29-20/h5-6,16-17,19H,3-4,7-15H2,1-2H3,(H,27,29)(H,33,34)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.47E+3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of human Biotinylated Fg binding to immobilized Alpha II beta-3				Bioorg Med Chem Lett 14: 5227-32 (2004) Article DOI: 10.1016/j.bmcl.2004.06.061 BindingDB Entry DOI: 10.7270/Q2TH8M5Z
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50153558 (3-Benzo[1,3]dioxol-5-yl-5-{1-[3-(5-hydroxy-1,4,5,6...) Show SMILES OC1CCC(Nc2cccc(c2)C(=O)N2CCC(CCC(CC(O)=O)c3ccc4OCOc4c3)CC2)=NC1 |c:39| Show InChI InChI=1S/C29H35N3O6/c33-24-7-9-27(30-17-24)31-23-3-1-2-22(14-23)29(36)32-12-10-19(11-13-32)4-5-21(16-28(34)35)20-6-8-25-26(15-20)38-18-37-25/h1-3,6,8,14-15,19,21,24,33H,4-5,7,9-13,16-18H2,(H,30,31)(H,34,35)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.58E+3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of human Biotinylated Fg binding to immobilized Alpha II beta-3				Bioorg Med Chem Lett 14: 5227-32 (2004) Article DOI: 10.1016/j.bmcl.2004.06.061 BindingDB Entry DOI: 10.7270/Q2TH8M5Z
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50153561 (3-({1-[4-(4,5-Dihydro-1H-imidazol-2-ylamino)-butyr...) Show SMILES OC(=O)CC(NC(=O)C1CCN(CC1)C(=O)CCCNC1=NCCN1)c1cccnc1 |t:21| Show InChI InChI=1S/C21H30N6O4/c28-18(4-2-8-23-21-24-9-10-25-21)27-11-5-15(6-12-27)20(31)26-17(13-19(29)30)16-3-1-7-22-14-16/h1,3,7,14-15,17H,2,4-6,8-13H2,(H,26,31)(H,29,30)(H2,23,24,25)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of human Biotinylated Fg binding to immobilized Alpha II beta-3				Bioorg Med Chem Lett 14: 5227-32 (2004) Article DOI: 10.1016/j.bmcl.2004.06.061 BindingDB Entry DOI: 10.7270/Q2TH8M5Z
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50153561 (3-({1-[4-(4,5-Dihydro-1H-imidazol-2-ylamino)-butyr...) Show SMILES OC(=O)CC(NC(=O)C1CCN(CC1)C(=O)CCCNC1=NCCN1)c1cccnc1 |t:21| Show InChI InChI=1S/C21H30N6O4/c28-18(4-2-8-23-21-24-9-10-25-21)27-11-5-15(6-12-27)20(31)26-17(13-19(29)30)16-3-1-7-22-14-16/h1,3,7,14-15,17H,2,4-6,8-13H2,(H,26,31)(H,29,30)(H2,23,24,25)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.81E+3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of human Biotinylated Fg binding to immobilized Alpha II beta-3				Bioorg Med Chem Lett 14: 5227-32 (2004) Article DOI: 10.1016/j.bmcl.2004.06.061 BindingDB Entry DOI: 10.7270/Q2TH8M5Z
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50153553 (3-Benzo[1,3]dioxol-5-yl-4-[1-(3-5,6,7,8-tetrahydro...) Show SMILES OC(=O)CC(CC1CCN(CC1)C(=O)CCc1ccc2CCCNc2n1)c1ccc2OCOc2c1 Show InChI InChI=1S/C27H33N3O5/c31-25(8-6-22-5-3-19-2-1-11-28-27(19)29-22)30-12-9-18(10-13-30)14-21(16-26(32)33)20-4-7-23-24(15-20)35-17-34-23/h3-5,7,15,18,21H,1-2,6,8-14,16-17H2,(H,28,29)(H,32,33)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.52E+3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of human Biotinylated Fg binding to immobilized Alpha II beta-3				Bioorg Med Chem Lett 14: 5227-32 (2004) Article DOI: 10.1016/j.bmcl.2004.06.061 BindingDB Entry DOI: 10.7270/Q2TH8M5Z
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50153573 (3-Quinolin-3-yl-3-{[1-(3-5,6,7,8-tetrahydro-[1,8]n...) Show SMILES OC(=O)CC(NC(=O)C1CCN(CC1)C(=O)CCc1ccc2CCCNc2n1)c1cnc2ccccc2c1 Show InChI InChI=1S/C29H33N5O4/c35-26(10-9-23-8-7-19-5-3-13-30-28(19)32-23)34-14-11-20(12-15-34)29(38)33-25(17-27(36)37)22-16-21-4-1-2-6-24(21)31-18-22/h1-2,4,6-8,16,18,20,25H,3,5,9-15,17H2,(H,30,32)(H,33,38)(H,36,37)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.85E+3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of human Biotinylated Fg binding to immobilized Alpha II beta-3				Bioorg Med Chem Lett 14: 5227-32 (2004) Article DOI: 10.1016/j.bmcl.2004.06.061 BindingDB Entry DOI: 10.7270/Q2TH8M5Z
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50153570 (3-Benzo[1,3]dioxol-5-yl-3-[1-(4-5,6,7,8-tetrahydro...) Show SMILES OC(=O)CC(C1CCN(CC1)C(=O)CCCc1ccc2CCCNc2n1)c1ccc2OCOc2c1 Show InChI InChI=1S/C27H33N3O5/c31-25(5-1-4-21-8-6-19-3-2-12-28-27(19)29-21)30-13-10-18(11-14-30)22(16-26(32)33)20-7-9-23-24(15-20)35-17-34-23/h6-9,15,18,22H,1-5,10-14,16-17H2,(H,28,29)(H,32,33)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.03E+3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of human Biotinylated Fg binding to immobilized Alpha II beta-3				Bioorg Med Chem Lett 14: 5227-32 (2004) Article DOI: 10.1016/j.bmcl.2004.06.061 BindingDB Entry DOI: 10.7270/Q2TH8M5Z
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50153563 (3-Benzo[1,3]dioxol-5-yl-4-[1-(4-5,6,7,8-tetrahydro...) Show SMILES OC(=O)CC(CC1CCN(CC1)C(=O)CCCc1ccc2CCCNc2n1)c1ccc2OCOc2c1 Show InChI InChI=1S/C28H35N3O5/c32-26(5-1-4-23-8-6-20-3-2-12-29-28(20)30-23)31-13-10-19(11-14-31)15-22(17-27(33)34)21-7-9-24-25(16-21)36-18-35-24/h6-9,16,19,22H,1-5,10-15,17-18H2,(H,29,30)(H,33,34)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.26E+3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of human Biotinylated Fg binding to immobilized Alpha II beta-3				Bioorg Med Chem Lett 14: 5227-32 (2004) Article DOI: 10.1016/j.bmcl.2004.06.061 BindingDB Entry DOI: 10.7270/Q2TH8M5Z
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50153557 (3-Benzo[1,3]dioxol-5-yl-5-[1-(3-5,6,7,8-tetrahydro...) Show SMILES OC(=O)CC(CCC1CCN(CC1)C(=O)CCc1ccc2CCCNc2n1)c1ccc2OCOc2c1 Show InChI InChI=1S/C28H35N3O5/c32-26(10-8-23-7-5-20-2-1-13-29-28(20)30-23)31-14-11-19(12-15-31)3-4-22(17-27(33)34)21-6-9-24-25(16-21)36-18-35-24/h5-7,9,16,19,22H,1-4,8,10-15,17-18H2,(H,29,30)(H,33,34)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.36E+3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of human Biotinylated Fg binding to immobilized Alpha II beta-3				Bioorg Med Chem Lett 14: 5227-32 (2004) Article DOI: 10.1016/j.bmcl.2004.06.061 BindingDB Entry DOI: 10.7270/Q2TH8M5Z
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50153562 (3-Benzo[1,3]dioxol-5-yl-3-[1-(3-5,6,7,8-tetrahydro...) Show SMILES OC(=O)CC(C1CCN(CC1)C(=O)CCc1ccc2CCCNc2n1)c1ccc2OCOc2c1 Show InChI InChI=1S/C26H31N3O5/c30-24(8-6-20-5-3-18-2-1-11-27-26(18)28-20)29-12-9-17(10-13-29)21(15-25(31)32)19-4-7-22-23(14-19)34-16-33-22/h3-5,7,14,17,21H,1-2,6,8-13,15-16H2,(H,27,28)(H,31,32)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of human Biotinylated Fg binding to immobilized Alpha II beta-3				Bioorg Med Chem Lett 14: 5227-32 (2004) Article DOI: 10.1016/j.bmcl.2004.06.061 BindingDB Entry DOI: 10.7270/Q2TH8M5Z
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50153566 (3-Pyridin-3-yl-4-[1-(3-5,6,7,8-tetrahydro-[1,8]nap...) Show SMILES OC(=O)CC(CC1CCN(CC1)C(=O)CCc1ccc2CCCNc2n1)c1cccnc1 Show InChI InChI=1S/C25H32N4O3/c30-23(8-7-22-6-5-19-3-2-12-27-25(19)28-22)29-13-9-18(10-14-29)15-21(16-24(31)32)20-4-1-11-26-17-20/h1,4-6,11,17-18,21H,2-3,7-10,12-16H2,(H,27,28)(H,31,32)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.61E+3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of human Biotinylated Fg binding to immobilized Alpha II beta-3				Bioorg Med Chem Lett 14: 5227-32 (2004) Article DOI: 10.1016/j.bmcl.2004.06.061 BindingDB Entry DOI: 10.7270/Q2TH8M5Z
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50153569 (3-Naphthalen-2-yl-4-[1-(3-5,6,7,8-tetrahydro-[1,8]...) Show SMILES OC(=O)CC(CC1CCN(CC1)C(=O)CCc1ccc2CCCNc2n1)c1ccc2ccccc2c1 Show InChI InChI=1S/C30H35N3O3/c34-28(12-11-27-10-9-23-6-3-15-31-30(23)32-27)33-16-13-21(14-17-33)18-26(20-29(35)36)25-8-7-22-4-1-2-5-24(22)19-25/h1-2,4-5,7-10,19,21,26H,3,6,11-18,20H2,(H,31,32)(H,35,36)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of human Biotinylated Fg binding to immobilized Alpha II beta-3				Bioorg Med Chem Lett 14: 5227-32 (2004) Article DOI: 10.1016/j.bmcl.2004.06.061 BindingDB Entry DOI: 10.7270/Q2TH8M5Z
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50153565 (3-Benzo[1,3]dioxol-5-yl-5-[1-(2-5,6,7,8-tetrahydro...) Show SMILES OC(=O)CC(CCC1CCN(CC1)C(=O)Cc1ccc2CCCNc2n1)c1ccc2OCOc2c1 Show InChI InChI=1S/C27H33N3O5/c31-25(16-22-7-5-19-2-1-11-28-27(19)29-22)30-12-9-18(10-13-30)3-4-21(15-26(32)33)20-6-8-23-24(14-20)35-17-34-23/h5-8,14,18,21H,1-4,9-13,15-17H2,(H,28,29)(H,32,33)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of human Biotinylated Fg binding to immobilized Alpha II beta-3				Bioorg Med Chem Lett 14: 5227-32 (2004) Article DOI: 10.1016/j.bmcl.2004.06.061 BindingDB Entry DOI: 10.7270/Q2TH8M5Z
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50153554 (3-(3-Fluoro-phenyl)-4-[1-(3-5,6,7,8-tetrahydro-[1,...) Show SMILES OC(=O)CC(CC1CCN(CC1)C(=O)CCc1ccc2CCCNc2n1)c1cccc(F)c1 Show InChI InChI=1S/C26H32FN3O3/c27-22-5-1-3-20(16-22)21(17-25(32)33)15-18-10-13-30(14-11-18)24(31)9-8-23-7-6-19-4-2-12-28-26(19)29-23/h1,3,5-7,16,18,21H,2,4,8-15,17H2,(H,28,29)(H,32,33)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of human Biotinylated Fg binding to immobilized Alpha II beta-3				Bioorg Med Chem Lett 14: 5227-32 (2004) Article DOI: 10.1016/j.bmcl.2004.06.061 BindingDB Entry DOI: 10.7270/Q2TH8M5Z
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50153556 (3-Benzo[1,3]dioxol-5-yl-3-[1-(2-5,6,7,8-tetrahydro...) Show SMILES OC(=O)CC(C1CCN(CC1)C(=O)Cc1ccc2CCCNc2n1)c1ccc2OCOc2c1 Show InChI InChI=1S/C25H29N3O5/c29-23(13-19-5-3-17-2-1-9-26-25(17)27-19)28-10-7-16(8-11-28)20(14-24(30)31)18-4-6-21-22(12-18)33-15-32-21/h3-6,12,16,20H,1-2,7-11,13-15H2,(H,26,27)(H,30,31)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of human Biotinylated Fg binding to immobilized Alpha IIb beta-3 (N=1)				Bioorg Med Chem Lett 14: 5227-32 (2004) Article DOI: 10.1016/j.bmcl.2004.06.061 BindingDB Entry DOI: 10.7270/Q2TH8M5Z
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50153560 (3-Benzo[1,3]dioxol-5-yl-5-{1-[4-(pyridin-2-ylamino...) Show SMILES OC(=O)CC(CCC1CCN(CC1)C(=O)CCCNc1ccccn1)c1ccc2OCOc2c1 Show InChI InChI=1S/C26H33N3O5/c30-25(5-3-13-28-24-4-1-2-12-27-24)29-14-10-19(11-15-29)6-7-21(17-26(31)32)20-8-9-22-23(16-20)34-18-33-22/h1-2,4,8-9,12,16,19,21H,3,5-7,10-11,13-15,17-18H2,(H,27,28)(H,31,32)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.09E+4	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of human Biotinylated Fg binding to immobilized Alpha II beta-3				Bioorg Med Chem Lett 14: 5227-32 (2004) Article DOI: 10.1016/j.bmcl.2004.06.061 BindingDB Entry DOI: 10.7270/Q2TH8M5Z
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50153567 (3-Benzo[1,3]dioxol-5-yl-3-{[1-(3-5,6,7,8-tetrahydr...) Show SMILES OC(=O)CC(NC(=O)C1CCN(CC1)C(=O)CCc1ccc2CCCNc2n1)c1ccc2OCOc2c1 Show InChI InChI=1S/C27H32N4O6/c32-24(8-6-20-5-3-17-2-1-11-28-26(17)29-20)31-12-9-18(10-13-31)27(35)30-21(15-25(33)34)19-4-7-22-23(14-19)37-16-36-22/h3-5,7,14,18,21H,1-2,6,8-13,15-16H2,(H,28,29)(H,30,35)(H,33,34)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.57E+4	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of human Biotinylated Fg binding to immobilized Alpha II beta-3				Bioorg Med Chem Lett 14: 5227-32 (2004) Article DOI: 10.1016/j.bmcl.2004.06.061 BindingDB Entry DOI: 10.7270/Q2TH8M5Z
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50104600 ((S)-3-{[(R)-1-(3-Piperidin-4-yl-propionyl)-piperid...) Show SMILES OC(=O)C[C@H](NC(=O)[C@@H]1CCCN(C1)C(=O)CCC1CCNCC1)c1cccnc1 Show InChI InChI=1S/C22H32N4O4/c27-20(6-5-16-7-10-23-11-8-16)26-12-2-4-18(15-26)22(30)25-19(13-21(28)29)17-3-1-9-24-14-17/h1,3,9,14,16,18-19,23H,2,4-8,10-13,15H2,(H,25,30)(H,28,29)/t18-,19+/m1/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of human vitronectin binding to immobilized Alpha v beta-3				Bioorg Med Chem Lett 14: 5227-32 (2004) Article DOI: 10.1016/j.bmcl.2004.06.061 BindingDB Entry DOI: 10.7270/Q2TH8M5Z
					More data for this Ligand-Target Pair