Found 31 hits Enz. Inhib. hit(s) with all data for entry = 50016406 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Ribosomal protein S6 kinase alpha-5
(Homo sapiens (Human)) | BDBM50168577
(4-(1-Cyclopropyl-1H-imidazo[4,5-c]pyridin-2-yl)-fu...)Show InChI InChI=1S/C11H10N6O/c12-10-9(15-18-16-10)11-14-7-5-13-4-3-8(7)17(11)6-1-2-6/h3-6H,1-2H2,(H2,12,16) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
| Assay Description Inhibitory concentration exhibited towards MSK-1 |
Bioorg Med Chem Lett 15: 3402-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.021 BindingDB Entry DOI: 10.7270/Q2Z037P9 |
More data for this Ligand-Target Pair | |
Ribosomal protein S6 kinase alpha-5
(Homo sapiens (Human)) | BDBM50168587
(4-(1-Cyclohexyl-1H-imidazo[4,5-c]pyridin-2-yl)-fur...)Show InChI InChI=1S/C14H16N6O/c15-13-12(18-21-19-13)14-17-10-8-16-7-6-11(10)20(14)9-4-2-1-3-5-9/h6-9H,1-5H2,(H2,15,19) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL MCE PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
| Assay Description Inhibitory concentration exhibited towards MSK-1 |
Bioorg Med Chem Lett 15: 3402-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.021 BindingDB Entry DOI: 10.7270/Q2Z037P9 |
More data for this Ligand-Target Pair | |
Ribosomal protein S6 kinase alpha-5
(Homo sapiens (Human)) | BDBM14032
(4-(1-ethyl-1H-imidazo[4,5-c]pyridin-2-yl)-1,2,5-ox...)Show InChI InChI=1S/C10H10N6O/c1-2-16-7-3-4-12-5-6(7)13-10(16)8-9(11)15-17-14-8/h3-5H,2H2,1H3,(H2,11,15) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
| Assay Description Inhibitory concentration exhibited towards MSK-1 |
Bioorg Med Chem Lett 15: 3402-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.021 BindingDB Entry DOI: 10.7270/Q2Z037P9 |
More data for this Ligand-Target Pair | |
Ribosomal protein S6 kinase alpha-5
(Homo sapiens (Human)) | BDBM50168581
(4-(1-Phenyl-1H-imidazo[4,5-c]pyridin-2-yl)-furazan...)Show InChI InChI=1S/C14H10N6O/c15-13-12(18-21-19-13)14-17-10-8-16-7-6-11(10)20(14)9-4-2-1-3-5-9/h1-8H,(H2,15,19) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
| Assay Description Inhibitory concentration exhibited towards MSK-1 |
Bioorg Med Chem Lett 15: 3402-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.021 BindingDB Entry DOI: 10.7270/Q2Z037P9 |
More data for this Ligand-Target Pair | |
Ribosomal protein S6 kinase alpha-5
(Homo sapiens (Human)) | BDBM50168578
(4-[1-(1-Amino-butyl)-1H-imidazo[4,5-c]pyridin-2-yl...)Show InChI InChI=1S/C12H15N7O/c1-2-3-9(13)19-8-4-5-15-6-7(8)16-12(19)10-11(14)18-20-17-10/h4-6,9H,2-3,13H2,1H3,(H2,14,18) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
| Assay Description Inhibitory concentration exhibited towards MSK-1 |
Bioorg Med Chem Lett 15: 3402-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.021 BindingDB Entry DOI: 10.7270/Q2Z037P9 |
More data for this Ligand-Target Pair | |
Ribosomal protein S6 kinase alpha-5
(Homo sapiens (Human)) | BDBM50168594
(2-(4-Amino-furazan-3-yl)-1-ethyl-1H-benzoimidazol-...)Show InChI InChI=1S/C11H11N5O2/c1-2-16-8-4-3-6(17)5-7(8)13-11(16)9-10(12)15-18-14-9/h3-5,17H,2H2,1H3,(H2,12,15) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
| Assay Description Inhibitory concentration exhibited towards MSK-1 |
Bioorg Med Chem Lett 15: 3402-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.021 BindingDB Entry DOI: 10.7270/Q2Z037P9 |
More data for this Ligand-Target Pair | |
Ribosomal protein S6 kinase alpha-5
(Homo sapiens (Human)) | BDBM50168601
(4-(1-Piperidin-4-yl-1H-imidazo[4,5-c]pyridin-2-yl)...)Show InChI InChI=1S/C13H15N7O/c14-12-11(18-21-19-12)13-17-9-7-16-6-3-10(9)20(13)8-1-4-15-5-2-8/h3,6-8,15H,1-2,4-5H2,(H2,14,19) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
| Assay Description Inhibitory concentration exhibited towards MSK-1 |
Bioorg Med Chem Lett 15: 3402-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.021 BindingDB Entry DOI: 10.7270/Q2Z037P9 |
More data for this Ligand-Target Pair | |
Ribosomal protein S6 kinase alpha-5
(Homo sapiens (Human)) | BDBM50168576
(3-(1-Ethyl-1H-imidazo[4,5-c]pyridin-2-yl)-pyrazin-...)Show InChI InChI=1S/C12H12N6/c1-2-18-9-3-4-14-7-8(9)17-12(18)10-11(13)16-6-5-15-10/h3-7H,2H2,1H3,(H2,13,16) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
| Assay Description Inhibitory concentration exhibited towards MSK-1 |
Bioorg Med Chem Lett 15: 3402-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.021 BindingDB Entry DOI: 10.7270/Q2Z037P9 |
More data for this Ligand-Target Pair | |
Ribosomal protein S6 kinase alpha-5
(Homo sapiens (Human)) | BDBM50168595
(4-(1-Ethyl-5-fluoro-1H-benzoimidazol-2-yl)-furazan...)Show InChI InChI=1S/C11H10FN5O/c1-2-17-8-4-3-6(12)5-7(8)14-11(17)9-10(13)16-18-15-9/h3-5H,2H2,1H3,(H2,13,16) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 38 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
| Assay Description Inhibitory concentration exhibited towards MSK-1 |
Bioorg Med Chem Lett 15: 3402-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.021 BindingDB Entry DOI: 10.7270/Q2Z037P9 |
More data for this Ligand-Target Pair | |
Ribosomal protein S6 kinase alpha-5
(Homo sapiens (Human)) | BDBM50168586
(4-(1-Ethyl-1H-imidazo[4,5-c]pyridin-2-yl)-5-methyl...)Show SMILES CCn1c(nc2cnccc12)-c1c(C)[nH]nc1N |(11.15,-8.55,;12.2,-7.41,;11.71,-5.96,;12.62,-4.7,;11.71,-3.45,;10.24,-3.93,;8.92,-3.16,;7.59,-3.93,;7.59,-5.48,;8.92,-6.24,;10.24,-5.48,;14.15,-4.58,;15.15,-5.75,;14.78,-7.24,;16.57,-5.17,;16.46,-3.64,;14.97,-3.26,;14.39,-1.85,)| Show InChI InChI=1S/C12H14N6/c1-3-18-9-4-5-14-6-8(9)15-12(18)10-7(2)16-17-11(10)13/h4-6H,3H2,1-2H3,(H3,13,16,17) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 55 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
| Assay Description Inhibitory concentration exhibited towards MSK-1 |
Bioorg Med Chem Lett 15: 3402-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.021 BindingDB Entry DOI: 10.7270/Q2Z037P9 |
More data for this Ligand-Target Pair | |
Ribosomal protein S6 kinase alpha-5
(Homo sapiens (Human)) | BDBM50168589
(3-(1-Ethyl-1H-imidazo[4,5-c]pyridin-2-yl)-pyridin-...)Show InChI InChI=1S/C13H13N5/c1-2-18-11-5-7-15-8-10(11)17-13(18)9-4-3-6-16-12(9)14/h3-8H,2H2,1H3,(H2,14,16) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 107 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
| Assay Description Inhibitory concentration exhibited towards MSK-1 |
Bioorg Med Chem Lett 15: 3402-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.021 BindingDB Entry DOI: 10.7270/Q2Z037P9 |
More data for this Ligand-Target Pair | |
Ribosomal protein S6 kinase alpha-5
(Homo sapiens (Human)) | BDBM50168582
(4-(1-Methyl-1H-imidazo[4,5-c]pyridin-2-yl)-furazan...)Show InChI InChI=1S/C9H8N6O/c1-15-6-2-3-11-4-5(6)12-9(15)7-8(10)14-16-13-7/h2-4H,1H3,(H2,10,14) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 126 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
| Assay Description Inhibitory concentration exhibited towards MSK-1 |
Bioorg Med Chem Lett 15: 3402-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.021 BindingDB Entry DOI: 10.7270/Q2Z037P9 |
More data for this Ligand-Target Pair | |
Ribosomal protein S6 kinase alpha-5
(Homo sapiens (Human)) | BDBM50168588
(4-(1-Ethyl-1H-benzoimidazol-2-yl)-furazan-3-ylamin...)Show InChI InChI=1S/C11H11N5O/c1-2-16-8-6-4-3-5-7(8)13-11(16)9-10(12)15-17-14-9/h3-6H,2H2,1H3,(H2,12,15) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
| Assay Description Inhibitory concentration exhibited towards MSK-1 |
Bioorg Med Chem Lett 15: 3402-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.021 BindingDB Entry DOI: 10.7270/Q2Z037P9 |
More data for this Ligand-Target Pair | |
Ribosomal protein S6 kinase alpha-5
(Homo sapiens (Human)) | BDBM50168593
(2-(4-Amino-furazan-3-yl)-3-ethyl-3H-benzoimidazol-...)Show InChI InChI=1S/C11H11N5O2/c1-2-16-8-5-6(17)3-4-7(8)13-11(16)9-10(12)15-18-14-9/h3-5,17H,2H2,1H3,(H2,12,15) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 258 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
| Assay Description Inhibitory concentration exhibited towards MSK-1 |
Bioorg Med Chem Lett 15: 3402-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.021 BindingDB Entry DOI: 10.7270/Q2Z037P9 |
More data for this Ligand-Target Pair | |
Ribosomal protein S6 kinase alpha-5
(Homo sapiens (Human)) | BDBM50168598
(CHEMBL185731 | [2-(4-Amino-furazan-3-yl)-1-ethyl-1...)Show InChI InChI=1S/C12H13N5O2/c1-2-17-9-4-3-7(6-18)5-8(9)14-12(17)10-11(13)16-19-15-10/h3-5,18H,2,6H2,1H3,(H2,13,16) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 974 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
| Assay Description Inhibitory concentration exhibited towards MSK-1 |
Bioorg Med Chem Lett 15: 3402-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.021 BindingDB Entry DOI: 10.7270/Q2Z037P9 |
More data for this Ligand-Target Pair | |
Ribosomal protein S6 kinase alpha-5
(Homo sapiens (Human)) | BDBM50168592
(4-(1-Ethyl-5-methoxy-1H-benzoimidazol-2-yl)-furaza...)Show InChI InChI=1S/C12H13N5O2/c1-3-17-9-5-4-7(18-2)6-8(9)14-12(17)10-11(13)16-19-15-10/h4-6H,3H2,1-2H3,(H2,13,16) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
| Assay Description Inhibitory concentration exhibited towards MSK-1 |
Bioorg Med Chem Lett 15: 3402-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.021 BindingDB Entry DOI: 10.7270/Q2Z037P9 |
More data for this Ligand-Target Pair | |
Ribosomal protein S6 kinase alpha-5
(Homo sapiens (Human)) | BDBM50168599
(4-(1-Ethyl-1H-imidazo[4,5-c]pyridin-2-yl)-1,5-dime...)Show SMILES CCn1c(nc2cnccc12)-c1c(N)nn(C)c1C |(11.18,-8.55,;12.21,-7.41,;11.73,-5.96,;12.64,-4.7,;11.73,-3.45,;10.27,-3.93,;8.93,-3.16,;7.61,-3.93,;7.61,-5.48,;8.93,-6.24,;10.27,-5.48,;14.18,-4.58,;14.99,-3.27,;14.4,-1.85,;16.48,-3.64,;16.6,-5.17,;17.9,-5.98,;15.18,-5.75,;14.81,-7.24,)| Show InChI InChI=1S/C13H16N6/c1-4-19-10-5-6-15-7-9(10)16-13(19)11-8(2)18(3)17-12(11)14/h5-7H,4H2,1-3H3,(H2,14,17) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.52E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
| Assay Description Inhibitory concentration exhibited towards MSK-1 |
Bioorg Med Chem Lett 15: 3402-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.021 BindingDB Entry DOI: 10.7270/Q2Z037P9 |
More data for this Ligand-Target Pair | |
Ribosomal protein S6 kinase alpha-5
(Homo sapiens (Human)) | BDBM50168584
(4-(3-Ethyl-3H-imidazo[4,5-c]pyridin-2-yl)-furazan-...)Show InChI InChI=1S/C10H10N6O/c1-2-16-7-5-12-4-3-6(7)13-10(16)8-9(11)15-17-14-8/h3-5H,2H2,1H3,(H2,11,15) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.54E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
| Assay Description Inhibitory concentration exhibited towards MSK-1 |
Bioorg Med Chem Lett 15: 3402-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.021 BindingDB Entry DOI: 10.7270/Q2Z037P9 |
More data for this Ligand-Target Pair | |
Ribosomal protein S6 kinase alpha-5
(Homo sapiens (Human)) | BDBM50168600
(4-(1H-Imidazo[4,5-c]pyridin-2-yl)-furazan-3-ylamin...)Show InChI InChI=1S/C8H6N6O/c9-7-6(13-15-14-7)8-11-4-1-2-10-3-5(4)12-8/h1-3H,(H2,9,14)(H,11,12) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.96E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
| Assay Description Inhibitory concentration exhibited towards MSK-1 |
Bioorg Med Chem Lett 15: 3402-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.021 BindingDB Entry DOI: 10.7270/Q2Z037P9 |
More data for this Ligand-Target Pair | |
Ribosomal protein S6 kinase alpha-5
(Homo sapiens (Human)) | BDBM50168591
(4-(1-Ethyl-6-fluoro-1H-benzoimidazol-2-yl)-furazan...)Show InChI InChI=1S/C11H10FN5O/c1-2-17-8-5-6(12)3-4-7(8)14-11(17)9-10(13)16-18-15-9/h3-5H,2H2,1H3,(H2,13,16) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 2.12E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
| Assay Description Inhibitory concentration exhibited towards MSK-1 |
Bioorg Med Chem Lett 15: 3402-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.021 BindingDB Entry DOI: 10.7270/Q2Z037P9 |
More data for this Ligand-Target Pair | |
Ribosomal protein S6 kinase alpha-5
(Homo sapiens (Human)) | BDBM50168583
(1-[2-(4-Amino-furazan-3-yl)-1-ethyl-1H-benzoimidaz...)Show InChI InChI=1S/C13H13N5O2/c1-3-18-10-5-4-8(7(2)19)6-9(10)15-13(18)11-12(14)17-20-16-11/h4-6H,3H2,1-2H3,(H2,14,17) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 4.39E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
| Assay Description Inhibitory concentration exhibited towards MSK-1 |
Bioorg Med Chem Lett 15: 3402-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.021 BindingDB Entry DOI: 10.7270/Q2Z037P9 |
More data for this Ligand-Target Pair | |
Ribosomal protein S6 kinase alpha-5
(Homo sapiens (Human)) | BDBM50168585
(CHEMBL362494 | N-[4-(1-Ethyl-1H-imidazo[4,5-c]pyri...)Show InChI InChI=1S/C12H12N6O2/c1-3-18-9-4-5-13-6-8(9)15-12(18)10-11(14-7(2)19)17-20-16-10/h4-6H,3H2,1-2H3,(H,14,17,19) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 5.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
| Assay Description Inhibitory concentration exhibited towards MSK-1 |
Bioorg Med Chem Lett 15: 3402-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.021 BindingDB Entry DOI: 10.7270/Q2Z037P9 |
More data for this Ligand-Target Pair | |
Ribosomal protein S6 kinase alpha-5
(Homo sapiens (Human)) | BDBM50168602
(4-(1-Ethyl-1H-imidazo[4,5-c]pyridin-2-yl)-5-methyl...)Show SMILES CCn1c(nc2cnccc12)-c1c(C)onc1N |(11.8,-8.55,;12.83,-7.41,;12.34,-5.96,;13.27,-4.7,;12.34,-3.45,;10.89,-3.93,;9.55,-3.16,;8.22,-3.93,;8.22,-5.48,;9.55,-6.24,;10.89,-5.48,;14.8,-4.58,;15.8,-5.75,;15.42,-7.24,;17.22,-5.17,;17.11,-3.64,;15.61,-3.26,;15.01,-1.85,)| Show InChI InChI=1S/C12H13N5O/c1-3-17-9-4-5-14-6-8(9)15-12(17)10-7(2)18-16-11(10)13/h4-6H,3H2,1-2H3,(H2,13,16) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
| Assay Description Inhibitory concentration exhibited towards MSK-1 |
Bioorg Med Chem Lett 15: 3402-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.021 BindingDB Entry DOI: 10.7270/Q2Z037P9 |
More data for this Ligand-Target Pair | |
Ribosomal protein S6 kinase alpha-5
(Homo sapiens (Human)) | BDBM50168596
(1-Ethyl-2-phenyl-1H-imidazo[4,5-c]pyridine | CHEMB...)Show InChI InChI=1S/C14H13N3/c1-2-17-13-8-9-15-10-12(13)16-14(17)11-6-4-3-5-7-11/h3-10H,2H2,1H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
| Assay Description Inhibitory concentration exhibited towards MSK-1 |
Bioorg Med Chem Lett 15: 3402-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.021 BindingDB Entry DOI: 10.7270/Q2Z037P9 |
More data for this Ligand-Target Pair | |
Ribosomal protein S6 kinase alpha-5
(Homo sapiens (Human)) | BDBM50168597
(2-(1,2-Dihydro-pyridin-4-yl)-1-ethyl-1H-imidazo[4,...)Show InChI InChI=1S/C13H14N4/c1-2-17-12-5-8-15-9-11(12)16-13(17)10-3-6-14-7-4-10/h3,5-6,8-9H,2,4,7H2,1H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
| Assay Description Inhibitory concentration exhibited towards MSK-1 |
Bioorg Med Chem Lett 15: 3402-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.021 BindingDB Entry DOI: 10.7270/Q2Z037P9 |
More data for this Ligand-Target Pair | |
Ribosomal protein S6 kinase alpha-5
(Homo sapiens (Human)) | BDBM50168590
(2-(4-Chloro-furazan-3-yl)-1-ethyl-1H-imidazo[4,5-c...)Show InChI InChI=1S/C10H8ClN5O/c1-2-16-7-3-4-12-5-6(7)13-10(16)8-9(11)15-17-14-8/h3-5H,2H2,1H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
| Assay Description Inhibitory concentration exhibited towards MSK-1 |
Bioorg Med Chem Lett 15: 3402-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.021 BindingDB Entry DOI: 10.7270/Q2Z037P9 |
More data for this Ligand-Target Pair | |
Ribosomal protein S6 kinase alpha-5
(Homo sapiens (Human)) | BDBM50168580
(2-(1,2-Dihydro-pyridin-2-yl)-1-ethyl-1H-imidazo[4,...)Show InChI InChI=1S/C13H14N4/c1-2-17-12-6-8-14-9-11(12)16-13(17)10-5-3-4-7-15-10/h3,5-10H,2,4H2,1H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
| Assay Description Inhibitory concentration exhibited towards MSK-1 |
Bioorg Med Chem Lett 15: 3402-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.021 BindingDB Entry DOI: 10.7270/Q2Z037P9 |
More data for this Ligand-Target Pair | |
Ribosomal protein S6 kinase alpha-5
(Homo sapiens (Human)) | BDBM50168579
(5-(1-Ethyl-1H-imidazo[4,5-c]pyridin-2-yl)-pyridin-...)Show InChI InChI=1S/C13H13N5/c1-2-18-11-5-6-15-8-10(11)17-13(18)9-3-4-12(14)16-7-9/h3-8H,2H2,1H3,(H2,14,16) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
| Assay Description Inhibitory concentration exhibited towards MSK-1 |
Bioorg Med Chem Lett 15: 3402-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.021 BindingDB Entry DOI: 10.7270/Q2Z037P9 |
More data for this Ligand-Target Pair | |
Ribosomal protein S6 kinase alpha-5
(Homo sapiens (Human)) | BDBM50168575
(1-Ethyl-2-pyridin-3-yl-1H-imidazo[4,5-c]pyridine |...)Show InChI InChI=1S/C13H12N4/c1-2-17-12-5-7-15-9-11(12)16-13(17)10-4-3-6-14-8-10/h3-9H,2H2,1H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
| Assay Description Inhibitory concentration exhibited towards MSK-1 |
Bioorg Med Chem Lett 15: 3402-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.021 BindingDB Entry DOI: 10.7270/Q2Z037P9 |
More data for this Ligand-Target Pair | |
Ribosomal protein S6 kinase alpha-5
(Homo sapiens (Human)) | BDBM50168574
(1-Ethyl-2-furan-3-yl-1H-imidazo[4,5-c]pyridine | C...)Show InChI InChI=1S/C12H11N3O/c1-2-15-11-3-5-13-7-10(11)14-12(15)9-4-6-16-8-9/h3-8H,2H2,1H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
| Assay Description Inhibitory concentration exhibited towards MSK-1 |
Bioorg Med Chem Lett 15: 3402-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.021 BindingDB Entry DOI: 10.7270/Q2Z037P9 |
More data for this Ligand-Target Pair | |
Ribosomal protein S6 kinase alpha-5
(Homo sapiens (Human)) | BDBM50168573
(3-(1-Ethyl-1H-imidazo[4,5-c]pyridin-2-yl)-pyridin-...)Show InChI InChI=1S/C13H12N4O/c1-2-17-11-5-7-14-8-10(11)16-12(17)9-4-3-6-15-13(9)18/h3-8H,2H2,1H3,(H,15,18) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
| Assay Description Inhibitory concentration exhibited towards MSK-1 |
Bioorg Med Chem Lett 15: 3402-6 (2005)
Article DOI: 10.1016/j.bmcl.2005.05.021 BindingDB Entry DOI: 10.7270/Q2Z037P9 |
More data for this Ligand-Target Pair | |