Compile Data Set for Download or QSAR

Found 20 hits Enz. Inhib. hit(s) with all data for entry = 50046026   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase B-raf (Homo sapiens (Human))	BDBM50091765 (CHEMBL3582396) Show SMILES Fc1ccc(NS(=O)(=O)c2cccnc2)c(F)c1C#Cc1cnc2[nH]nc(-c3ccncc3)c2c1 Show InChI InChI=1S/C24H14F2N6O2S/c25-20-5-6-21(32-35(33,34)17-2-1-9-28-14-17)22(26)18(20)4-3-15-12-19-23(16-7-10-27-11-8-16)30-31-24(19)29-13-15/h1-2,5-14,32H,(H,29,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Guangzhou Institutes of Biomedicine and Health Curated by ChEMBL					Assay Description Inhibition of human recombinant B-Raf V600E mutant by FRET-based Z'-lyte assay				ACS Med Chem Lett 6: 543-7 (2015) Article DOI: 10.1021/acsmedchemlett.5b00039 BindingDB Entry DOI: 10.7270/Q26W9CT5
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf (Homo sapiens (Human))	BDBM50091819 (CHEMBL3582394) Show SMILES Fc1ccc(NS(=O)(=O)c2cccnc2)c(F)c1C#Cc1cnc2[nH]nc(C3CC3)c2c1 Show InChI InChI=1S/C22H15F2N5O2S/c23-18-7-8-19(29-32(30,31)15-2-1-9-25-12-15)20(24)16(18)6-3-13-10-17-21(14-4-5-14)27-28-22(17)26-11-13/h1-2,7-12,14,29H,4-5H2,(H,26,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Guangzhou Institutes of Biomedicine and Health Curated by ChEMBL					Assay Description Inhibition of human recombinant B-Raf V600E mutant by FRET-based Z'-lyte assay				ACS Med Chem Lett 6: 543-7 (2015) Article DOI: 10.1021/acsmedchemlett.5b00039 BindingDB Entry DOI: 10.7270/Q26W9CT5
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf (Homo sapiens (Human))	BDBM50091712 (CHEMBL3582400) Show SMILES Fc1ccc(cc1)-c1n[nH]c2ncc(cc12)C#Cc1c(F)ccc(NS(=O)(=O)c2cccnc2)c1F Show InChI InChI=1S/C32H35F2N5O5/c1-43-18-26-27(29(40)44-2)28(20-8-11-24(33)25(34)16-20)39(31(42)37-26)30(41)36-22-9-10-23(17-22)38-14-12-32(19-35,13-15-38)21-6-4-3-5-7-21/h3-8,11,16,22-23,28H,9-10,12-15,17-18H2,1-2H3,(H,36,41)(H,37,42)/t22?,23-,28-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Guangzhou Institutes of Biomedicine and Health Curated by ChEMBL					Assay Description Inhibition of human recombinant B-Raf V600E mutant by FRET-based Z'-lyte assay				ACS Med Chem Lett 6: 543-7 (2015) Article DOI: 10.1021/acsmedchemlett.5b00039 BindingDB Entry DOI: 10.7270/Q26W9CT5
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf (Homo sapiens (Human))	BDBM50091796 (CHEMBL3582395) Show SMILES Fc1ccc(NS(=O)(=O)c2cccnc2)c(F)c1C#Cc1cnc2[nH]nc(-c3ccccc3)c2c1 Show InChI InChI=1S/C8H17N3O2/c9-4-2-1-3-7(8(12)13)11-6-5-10/h5,7,10-11H,1-4,6,9H2,(H,12,13)/t7-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Guangzhou Institutes of Biomedicine and Health Curated by ChEMBL					Assay Description Inhibition of human recombinant B-Raf V600E mutant by FRET-based Z'-lyte assay				ACS Med Chem Lett 6: 543-7 (2015) Article DOI: 10.1021/acsmedchemlett.5b00039 BindingDB Entry DOI: 10.7270/Q26W9CT5
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf (Homo sapiens (Human))	BDBM50091864 (CHEMBL3582391) Show SMILES COc1n[nH]c2ncc(cc12)C#Cc1c(F)ccc(NS(=O)(=O)c2cccnc2)c1F Show InChI InChI=1S/C20H13F2N5O3S/c1-30-20-15-9-12(10-24-19(15)25-26-20)4-5-14-16(21)6-7-17(18(14)22)27-31(28,29)13-3-2-8-23-11-13/h2-3,6-11,27H,1H3,(H,24,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Guangzhou Institutes of Biomedicine and Health Curated by ChEMBL					Assay Description Inhibition of human recombinant B-Raf V600E mutant by FRET-based Z'-lyte assay				ACS Med Chem Lett 6: 543-7 (2015) Article DOI: 10.1021/acsmedchemlett.5b00039 BindingDB Entry DOI: 10.7270/Q26W9CT5
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf (Homo sapiens (Human))	BDBM50091762 (CHEMBL3582399) Show SMILES Fc1ccc(NS(=O)(=O)c2cccnc2)c(F)c1C#Cc1cnc2[nH]nc(-c3ccc(Cl)cc3)c2c1 Show InChI InChI=1S/C25H14ClF2N5O2S/c26-17-6-4-16(5-7-17)24-20-12-15(13-30-25(20)32-31-24)3-8-19-21(27)9-10-22(23(19)28)33-36(34,35)18-2-1-11-29-14-18/h1-2,4-7,9-14,33H,(H,30,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Guangzhou Institutes of Biomedicine and Health Curated by ChEMBL					Assay Description Inhibition of human recombinant B-Raf V600E mutant by FRET-based Z'-lyte assay				ACS Med Chem Lett 6: 543-7 (2015) Article DOI: 10.1021/acsmedchemlett.5b00039 BindingDB Entry DOI: 10.7270/Q26W9CT5
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf (Homo sapiens (Human))	BDBM50091820 (CHEMBL3582393) Show SMILES Cc1n[nH]c2ncc(cc12)C#Cc1c(F)ccc(NS(=O)(=O)c2cccnc2)c1F Show InChI InChI=1S/C20H13F2N5O2S/c1-12-16-9-13(10-24-20(16)26-25-12)4-5-15-17(21)6-7-18(19(15)22)27-30(28,29)14-3-2-8-23-11-14/h2-3,6-11,27H,1H3,(H,24,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Guangzhou Institutes of Biomedicine and Health Curated by ChEMBL					Assay Description Inhibition of human recombinant B-Raf V600E mutant by FRET-based Z'-lyte assay				ACS Med Chem Lett 6: 543-7 (2015) Article DOI: 10.1021/acsmedchemlett.5b00039 BindingDB Entry DOI: 10.7270/Q26W9CT5
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf (Homo sapiens (Human))	BDBM50396483 (PLX-4032 | RG 7204 | Ro 5185426 | US10570155, Vemu...) Show SMILES CCCS(=O)(=O)Nc1ccc(F)c(C(=O)c2c[nH]c3ncc(cc23)-c2ccc(Cl)cc2)c1F Show InChI InChI=1S/C23H18ClF2N3O3S/c1-2-9-33(31,32)29-19-8-7-18(25)20(21(19)26)22(30)17-12-28-23-16(17)10-14(11-27-23)13-3-5-15(24)6-4-13/h3-8,10-12,29H,2,9H2,1H3,(H,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid PDB UniChem Similars	DrugBank PDB Article PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
Guangzhou Institutes of Biomedicine and Health Curated by ChEMBL					Assay Description Inhibition of human recombinant B-Raf V600E mutant by FRET-based Z'-lyte assay				ACS Med Chem Lett 6: 543-7 (2015) Article DOI: 10.1021/acsmedchemlett.5b00039 BindingDB Entry DOI: 10.7270/Q26W9CT5
					More data for this Ligand-Target Pair				3D Structure (crystal)
Serine/threonine-protein kinase B-raf (Homo sapiens (Human))	BDBM50091881 (CHEMBL3582388) Show SMILES Fc1ccc(NS(=O)(=O)c2cccnc2)c(F)c1C#Cc1cnc2[nH]ccc2c1 Show InChI InChI=1S/C27H34N2O4S/c1-3-18(2)23(34)24(30)29-27(15-7-8-16-27)26(33)28-22(25(31)32)17-19-11-13-21(14-12-19)20-9-5-4-6-10-20/h4-6,9-14,18,22-23,34H,3,7-8,15-17H2,1-2H3,(H,28,33)(H,29,30)(H,31,32)/t18?,22-,23+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
Guangzhou Institutes of Biomedicine and Health Curated by ChEMBL					Assay Description Inhibition of human recombinant B-Raf V600E mutant by FRET-based Z'-lyte assay				ACS Med Chem Lett 6: 543-7 (2015) Article DOI: 10.1021/acsmedchemlett.5b00039 BindingDB Entry DOI: 10.7270/Q26W9CT5
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf (Homo sapiens (Human))	BDBM50091957 (CHEMBL3582387) Show SMILES Fc1ccc(NS(=O)(=O)c2cccnc2)c(F)c1C#Cc1cnc2[nH]ncc2c1 Show InChI InChI=1S/C19H11F2N5O2S/c20-16-5-6-17(26-29(27,28)14-2-1-7-22-11-14)18(21)15(16)4-3-12-8-13-10-24-25-19(13)23-9-12/h1-2,5-11,26H,(H,23,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
Guangzhou Institutes of Biomedicine and Health Curated by ChEMBL					Assay Description Inhibition of human recombinant B-Raf V600E mutant by FRET-based Z'-lyte assay				ACS Med Chem Lett 6: 543-7 (2015) Article DOI: 10.1021/acsmedchemlett.5b00039 BindingDB Entry DOI: 10.7270/Q26W9CT5
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf (Homo sapiens (Human))	BDBM50092011 (CHEMBL3582384) Show SMILES Fc1cccc(c1)S(=O)(=O)Nc1ccc(F)c(C#Cc2cnc3[nH]ncc3c2)c1F Show InChI InChI=1S/C20H11F3N4O2S/c21-14-2-1-3-15(9-14)30(28,29)27-18-7-6-17(22)16(19(18)23)5-4-12-8-13-11-25-26-20(13)24-10-12/h1-3,6-11,27H,(H,24,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	68	n/a	n/a	n/a	n/a	n/a	n/a
Guangzhou Institutes of Biomedicine and Health Curated by ChEMBL					Assay Description Inhibition of human recombinant B-Raf V600E mutant by FRET-based Z'-lyte assay				ACS Med Chem Lett 6: 543-7 (2015) Article DOI: 10.1021/acsmedchemlett.5b00039 BindingDB Entry DOI: 10.7270/Q26W9CT5
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf (Homo sapiens (Human))	BDBM50091763 (CHEMBL3582398) Show SMILES Fc1ccc(NS(=O)(=O)c2cccnc2)c(F)c1C#Cc1cnc2[nH]nc(-c3cccc(Cl)c3)c2c1 Show InChI InChI=1S/C25H14ClF2N5O2S/c26-17-4-1-3-16(12-17)24-20-11-15(13-30-25(20)32-31-24)6-7-19-21(27)8-9-22(23(19)28)33-36(34,35)18-5-2-10-29-14-18/h1-5,8-14,33H,(H,30,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	107	n/a	n/a	n/a	n/a	n/a	n/a
Guangzhou Institutes of Biomedicine and Health Curated by ChEMBL					Assay Description Inhibition of human recombinant B-Raf V600E mutant by FRET-based Z'-lyte assay				ACS Med Chem Lett 6: 543-7 (2015) Article DOI: 10.1021/acsmedchemlett.5b00039 BindingDB Entry DOI: 10.7270/Q26W9CT5
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf (Homo sapiens (Human))	BDBM50091863 (CHEMBL3582392) Show SMILES CCOc1n[nH]c2ncc(cc12)C#Cc1c(F)ccc(NS(=O)(=O)c2cccnc2)c1F Show InChI InChI=1S/C21H15F2N5O3S/c1-2-31-21-16-10-13(11-25-20(16)26-27-21)5-6-15-17(22)7-8-18(19(15)23)28-32(29,30)14-4-3-9-24-12-14/h3-4,7-12,28H,2H2,1H3,(H,25,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	122	n/a	n/a	n/a	n/a	n/a	n/a
Guangzhou Institutes of Biomedicine and Health Curated by ChEMBL					Assay Description Inhibition of human recombinant B-Raf V600E mutant by FRET-based Z'-lyte assay				ACS Med Chem Lett 6: 543-7 (2015) Article DOI: 10.1021/acsmedchemlett.5b00039 BindingDB Entry DOI: 10.7270/Q26W9CT5
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf (Homo sapiens (Human))	BDBM50091764 (CHEMBL3582397) Show SMILES Fc1ccc(NS(=O)(=O)c2cccnc2)c(F)c1C#Cc1cnc2[nH]nc(-c3ccccc3Cl)c2c1 Show InChI InChI=1S/C25H14ClF2N5O2S/c26-20-6-2-1-5-17(20)24-19-12-15(13-30-25(19)32-31-24)7-8-18-21(27)9-10-22(23(18)28)33-36(34,35)16-4-3-11-29-14-16/h1-6,9-14,33H,(H,30,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	131	n/a	n/a	n/a	n/a	n/a	n/a
Guangzhou Institutes of Biomedicine and Health Curated by ChEMBL					Assay Description Inhibition of human recombinant B-Raf V600E mutant by FRET-based Z'-lyte assay				ACS Med Chem Lett 6: 543-7 (2015) Article DOI: 10.1021/acsmedchemlett.5b00039 BindingDB Entry DOI: 10.7270/Q26W9CT5
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf (Homo sapiens (Human))	BDBM50092013 (CHEMBL3582382) Show SMILES Fc1ccc(NS(=O)(=O)c2ccccc2)c(F)c1C#Cc1cnc2[nH]ncc2c1 Show InChI InChI=1S/C20H12F2N4O2S/c21-17-8-9-18(26-29(27,28)15-4-2-1-3-5-15)19(22)16(17)7-6-13-10-14-12-24-25-20(14)23-11-13/h1-5,8-12,26H,(H,23,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	149	n/a	n/a	n/a	n/a	n/a	n/a
Guangzhou Institutes of Biomedicine and Health Curated by ChEMBL					Assay Description Inhibition of human recombinant B-Raf V600E mutant by FRET-based Z'-lyte assay				ACS Med Chem Lett 6: 543-7 (2015) Article DOI: 10.1021/acsmedchemlett.5b00039 BindingDB Entry DOI: 10.7270/Q26W9CT5
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf (Homo sapiens (Human))	BDBM50092012 (CHEMBL3582383) Show SMILES Fc1ccccc1S(=O)(=O)Nc1ccc(F)c(C#Cc2cnc3[nH]ncc3c2)c1F Show InChI InChI=1S/C20H11F3N4O2S/c21-15-7-8-17(27-30(28,29)18-4-2-1-3-16(18)22)19(23)14(15)6-5-12-9-13-11-25-26-20(13)24-10-12/h1-4,7-11,27H,(H,24,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	177	n/a	n/a	n/a	n/a	n/a	n/a
Guangzhou Institutes of Biomedicine and Health Curated by ChEMBL					Assay Description Inhibition of human recombinant B-Raf V600E mutant by FRET-based Z'-lyte assay				ACS Med Chem Lett 6: 543-7 (2015) Article DOI: 10.1021/acsmedchemlett.5b00039 BindingDB Entry DOI: 10.7270/Q26W9CT5
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf (Homo sapiens (Human))	BDBM50091865 (CHEMBL3582390) Show SMILES Fc1ccc(NS(=O)(=O)c2cccnc2)c(F)c1C#Cc1cnc2ccnn2c1 Show InChI InChI=1S/C19H11F2N5O2S/c20-16-5-6-17(25-29(27,28)14-2-1-8-22-11-14)19(21)15(16)4-3-13-10-23-18-7-9-24-26(18)12-13/h1-2,5-12,25H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	533	n/a	n/a	n/a	n/a	n/a	n/a
Guangzhou Institutes of Biomedicine and Health Curated by ChEMBL					Assay Description Inhibition of human recombinant B-Raf V600E mutant by FRET-based Z'-lyte assay				ACS Med Chem Lett 6: 543-7 (2015) Article DOI: 10.1021/acsmedchemlett.5b00039 BindingDB Entry DOI: 10.7270/Q26W9CT5
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf (Homo sapiens (Human))	BDBM50091974 (CHEMBL3582386) Show SMILES Fc1ccc(NS(=O)(=O)c2ccccn2)c(F)c1C#Cc1cnc2[nH]ncc2c1 Show InChI InChI=1S/C19H11F2N5O2S/c20-15-6-7-16(26-29(27,28)17-3-1-2-8-22-17)18(21)14(15)5-4-12-9-13-11-24-25-19(13)23-10-12/h1-3,6-11,26H,(H,23,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	593	n/a	n/a	n/a	n/a	n/a	n/a
Guangzhou Institutes of Biomedicine and Health Curated by ChEMBL					Assay Description Inhibition of human recombinant B-Raf V600E mutant by FRET-based Z'-lyte assay				ACS Med Chem Lett 6: 543-7 (2015) Article DOI: 10.1021/acsmedchemlett.5b00039 BindingDB Entry DOI: 10.7270/Q26W9CT5
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf (Homo sapiens (Human))	BDBM50092010 (CHEMBL3582385) Show SMILES Fc1ccc(cc1)S(=O)(=O)Nc1ccc(F)c(C#Cc2cnc3[nH]ncc3c2)c1F Show InChI InChI=1S/C20H11F3N4O2S/c21-14-2-4-15(5-3-14)30(28,29)27-18-8-7-17(22)16(19(18)23)6-1-12-9-13-11-25-26-20(13)24-10-12/h2-5,7-11,27H,(H,24,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	917	n/a	n/a	n/a	n/a	n/a	n/a
Guangzhou Institutes of Biomedicine and Health Curated by ChEMBL					Assay Description Inhibition of human recombinant B-Raf V600E mutant by FRET-based Z'-lyte assay				ACS Med Chem Lett 6: 543-7 (2015) Article DOI: 10.1021/acsmedchemlett.5b00039 BindingDB Entry DOI: 10.7270/Q26W9CT5
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf (Homo sapiens (Human))	BDBM50091866 (CHEMBL3582389) Show SMILES Fc1ccc(NS(=O)(=O)c2cccnc2)c(F)c1C#Cc1ccc2[nH]ncc2c1 Show InChI InChI=1S/C20H12F2N4O2S/c21-17-6-8-19(26-29(27,28)15-2-1-9-23-12-15)20(22)16(17)5-3-13-4-7-18-14(10-13)11-24-25-18/h1-2,4,6-12,26H,(H,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.31E+3	n/a	n/a	n/a	n/a	n/a	n/a
Guangzhou Institutes of Biomedicine and Health Curated by ChEMBL					Assay Description Inhibition of human recombinant B-Raf V600E mutant by FRET-based Z'-lyte assay				ACS Med Chem Lett 6: 543-7 (2015) Article DOI: 10.1021/acsmedchemlett.5b00039 BindingDB Entry DOI: 10.7270/Q26W9CT5
					More data for this Ligand-Target Pair