Found 111 hits Enz. Inhib. hit(s) with all data for entry = 50032704 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50333450
((R)-3-(2-(2-chloro-6-fluorophenoxy)-6-fluorophenox...)Show InChI InChI=1S/C16H14ClF2NO2/c17-11-3-1-4-12(18)15(11)22-14-6-2-5-13(19)16(14)21-10-7-8-20-9-10/h1-6,10,20H,7-9H2/t10-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by liquid scintillation spectrophotometry |
Bioorg Med Chem Lett 21: 865-8 (2011)
Article DOI: 10.1016/j.bmcl.2010.11.066 BindingDB Entry DOI: 10.7270/Q2HT2PK6 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50333433
(3-(2-(2-chloro-6-fluorophenoxy)-6-fluorophenoxy)az...)Show InChI InChI=1S/C15H12ClF2NO2/c16-10-3-1-4-11(17)14(10)21-13-6-2-5-12(18)15(13)20-9-7-19-8-9/h1-6,9,19H,7-8H2 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by liquid scintillation spectrophotometry |
Bioorg Med Chem Lett 21: 865-8 (2011)
Article DOI: 10.1016/j.bmcl.2010.11.066 BindingDB Entry DOI: 10.7270/Q2HT2PK6 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50333448
(3-(2-(2-chloro-6-fluorophenoxy)-6-fluorophenoxy)py...)Show InChI InChI=1S/C16H14ClF2NO2/c17-11-3-1-4-12(18)15(11)22-14-6-2-5-13(19)16(14)21-10-7-8-20-9-10/h1-6,10,20H,7-9H2 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by liquid scintillation spectrophotometry |
Bioorg Med Chem Lett 21: 865-8 (2011)
Article DOI: 10.1016/j.bmcl.2010.11.066 BindingDB Entry DOI: 10.7270/Q2HT2PK6 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50333434
(3-(2-fluoro-6-(2-fluoro-6-methylphenoxy)phenoxy)az...)Show InChI InChI=1S/C16H15F2NO2/c1-10-4-2-5-12(17)15(10)21-14-7-3-6-13(18)16(14)20-11-8-19-9-11/h2-7,11,19H,8-9H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by liquid scintillation spectrophotometry |
Bioorg Med Chem Lett 21: 865-8 (2011)
Article DOI: 10.1016/j.bmcl.2010.11.066 BindingDB Entry DOI: 10.7270/Q2HT2PK6 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50333447
(3-(2-fluoro-6-(2-fluoro-6-methylphenoxy)phenoxy)py...)Show InChI InChI=1S/C17H17F2NO2/c1-11-4-2-5-13(18)16(11)22-15-7-3-6-14(19)17(15)21-12-8-9-20-10-12/h2-7,12,20H,8-10H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by liquid scintillation spectrophotometry |
Bioorg Med Chem Lett 21: 865-8 (2011)
Article DOI: 10.1016/j.bmcl.2010.11.066 BindingDB Entry DOI: 10.7270/Q2HT2PK6 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50333442
(4-(2-fluoro-6-(2-fluoro-6-methylphenoxy)phenoxy)pi...)Show InChI InChI=1S/C18H19F2NO2/c1-12-4-2-5-14(19)17(12)23-16-7-3-6-15(20)18(16)22-13-8-10-21-11-9-13/h2-7,13,21H,8-11H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by liquid scintillation spectrophotometry |
Bioorg Med Chem Lett 21: 865-8 (2011)
Article DOI: 10.1016/j.bmcl.2010.11.066 BindingDB Entry DOI: 10.7270/Q2HT2PK6 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50309505
(4-(2-fluoro-6-(2-fluorophenoxy)phenyl)piperidine |...)Show InChI InChI=1S/C17H17F2NO/c18-13-4-1-2-6-15(13)21-16-7-3-5-14(19)17(16)12-8-10-20-11-9-12/h1-7,12,20H,8-11H2 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 4.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by liquid scintillation spectrophotometry |
Bioorg Med Chem Lett 21: 865-8 (2011)
Article DOI: 10.1016/j.bmcl.2010.11.066 BindingDB Entry DOI: 10.7270/Q2HT2PK6 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50333436
(3-(2-(2,6-dichlorophenoxy)-6-fluorophenoxy)azetidi...)Show InChI InChI=1S/C15H12Cl2FNO2/c16-10-3-1-4-11(17)14(10)21-13-6-2-5-12(18)15(13)20-9-7-19-8-9/h1-6,9,19H,7-8H2 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by liquid scintillation spectrophotometry |
Bioorg Med Chem Lett 21: 865-8 (2011)
Article DOI: 10.1016/j.bmcl.2010.11.066 BindingDB Entry DOI: 10.7270/Q2HT2PK6 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50333445
(3-(2-fluoro-6-(2-fluorophenoxy)phenoxy)pyrrolidine...)Show InChI InChI=1S/C16H15F2NO2/c17-12-4-1-2-6-14(12)21-15-7-3-5-13(18)16(15)20-11-8-9-19-10-11/h1-7,11,19H,8-10H2 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by liquid scintillation spectrophotometry |
Bioorg Med Chem Lett 21: 865-8 (2011)
Article DOI: 10.1016/j.bmcl.2010.11.066 BindingDB Entry DOI: 10.7270/Q2HT2PK6 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50333441
(4-(2-(2-chloro-6-fluorophenoxy)-6-fluorophenoxy)pi...)Show InChI InChI=1S/C17H16ClF2NO2/c18-12-3-1-4-13(19)16(12)23-15-6-2-5-14(20)17(15)22-11-7-9-21-10-8-11/h1-6,11,21H,7-10H2 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by liquid scintillation spectrophotometry |
Bioorg Med Chem Lett 21: 865-8 (2011)
Article DOI: 10.1016/j.bmcl.2010.11.066 BindingDB Entry DOI: 10.7270/Q2HT2PK6 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50309519
(2-(2-chloro-6-fluorophenoxy)-3-(piperidin-4-yl)pyr...)Show InChI InChI=1S/C16H16ClFN2O/c17-13-4-1-5-14(18)15(13)21-16-12(3-2-8-20-16)11-6-9-19-10-7-11/h1-5,8,11,19H,6-7,9-10H2 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 11 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by liquid scintillation spectrophotometry |
Bioorg Med Chem Lett 21: 865-8 (2011)
Article DOI: 10.1016/j.bmcl.2010.11.066 BindingDB Entry DOI: 10.7270/Q2HT2PK6 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50333431
(3-(2-fluoro-6-(2-fluorophenoxy)phenoxy)azetidine |...)Show InChI InChI=1S/C15H13F2NO2/c16-11-4-1-2-6-13(11)20-14-7-3-5-12(17)15(14)19-10-8-18-9-10/h1-7,10,18H,8-9H2 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by liquid scintillation spectrophotometry |
Bioorg Med Chem Lett 21: 865-8 (2011)
Article DOI: 10.1016/j.bmcl.2010.11.066 BindingDB Entry DOI: 10.7270/Q2HT2PK6 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50333449
((S)-3-(2-(2-chloro-6-fluorophenoxy)-6-fluorophenox...)Show InChI InChI=1S/C16H14ClF2NO2/c17-11-3-1-4-12(18)15(11)22-14-6-2-5-13(19)16(14)21-10-7-8-20-9-10/h1-6,10,20H,7-9H2/t10-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by liquid scintillation spectrophotometry |
Bioorg Med Chem Lett 21: 865-8 (2011)
Article DOI: 10.1016/j.bmcl.2010.11.066 BindingDB Entry DOI: 10.7270/Q2HT2PK6 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50333432
(3-(2-(2-chlorophenoxy)-6-fluorophenoxy)azetidine |...)Show InChI InChI=1S/C15H13ClFNO2/c16-11-4-1-2-6-13(11)20-14-7-3-5-12(17)15(14)19-10-8-18-9-10/h1-7,10,18H,8-9H2 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 14 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by liquid scintillation spectrophotometry |
Bioorg Med Chem Lett 21: 865-8 (2011)
Article DOI: 10.1016/j.bmcl.2010.11.066 BindingDB Entry DOI: 10.7270/Q2HT2PK6 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50333438
(3-(2-(2,3-dichlorophenoxy)-6-fluorophenoxy)azetidi...)Show InChI InChI=1S/C15H12Cl2FNO2/c16-10-3-1-5-12(14(10)17)21-13-6-2-4-11(18)15(13)20-9-7-19-8-9/h1-6,9,19H,7-8H2 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by liquid scintillation spectrophotometry |
Bioorg Med Chem Lett 21: 865-8 (2011)
Article DOI: 10.1016/j.bmcl.2010.11.066 BindingDB Entry DOI: 10.7270/Q2HT2PK6 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50333437
(3-(2-(2-chloro-6-methylphenoxy)-6-fluorophenoxy)az...)Show InChI InChI=1S/C16H15ClFNO2/c1-10-4-2-5-12(17)15(10)21-14-7-3-6-13(18)16(14)20-11-8-19-9-11/h2-7,11,19H,8-9H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by liquid scintillation spectrophotometry |
Bioorg Med Chem Lett 21: 865-8 (2011)
Article DOI: 10.1016/j.bmcl.2010.11.066 BindingDB Entry DOI: 10.7270/Q2HT2PK6 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50333446
(3-(2-(2-chlorophenoxy)-6-fluorophenoxy)pyrrolidine...)Show InChI InChI=1S/C16H15ClFNO2/c17-12-4-1-2-6-14(12)21-15-7-3-5-13(18)16(15)20-11-8-9-19-10-11/h1-7,11,19H,8-10H2 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 19 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by liquid scintillation spectrophotometry |
Bioorg Med Chem Lett 21: 865-8 (2011)
Article DOI: 10.1016/j.bmcl.2010.11.066 BindingDB Entry DOI: 10.7270/Q2HT2PK6 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50333430
(3-(2-(2-fluorophenoxy)phenoxy)azetidine | CHEMBL16...)Show InChI InChI=1S/C15H14FNO2/c16-12-5-1-2-6-13(12)19-15-8-4-3-7-14(15)18-11-9-17-10-11/h1-8,11,17H,9-10H2 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 22 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by liquid scintillation spectrophotometry |
Bioorg Med Chem Lett 21: 865-8 (2011)
Article DOI: 10.1016/j.bmcl.2010.11.066 BindingDB Entry DOI: 10.7270/Q2HT2PK6 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50333440
(4-(2-fluoro-6-(2-fluorophenoxy)phenoxy)piperidine ...)Show InChI InChI=1S/C17H17F2NO2/c18-13-4-1-2-6-15(13)22-16-7-3-5-14(19)17(16)21-12-8-10-20-11-9-12/h1-7,12,20H,8-11H2 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by liquid scintillation spectrophotometry |
Bioorg Med Chem Lett 21: 865-8 (2011)
Article DOI: 10.1016/j.bmcl.2010.11.066 BindingDB Entry DOI: 10.7270/Q2HT2PK6 |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50309505
(4-(2-fluoro-6-(2-fluorophenoxy)phenyl)piperidine |...)Show InChI InChI=1S/C17H17F2NO/c18-13-4-1-2-6-15(13)21-16-7-3-5-14(19)17(16)12-8-10-20-11-9-12/h1-7,12,20H,8-11H2 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 32 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]nisoxetine from human NET by scintillation proximity assay |
Bioorg Med Chem Lett 21: 865-8 (2011)
Article DOI: 10.1016/j.bmcl.2010.11.066 BindingDB Entry DOI: 10.7270/Q2HT2PK6 |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50309519
(2-(2-chloro-6-fluorophenoxy)-3-(piperidin-4-yl)pyr...)Show InChI InChI=1S/C16H16ClFN2O/c17-13-4-1-5-14(18)15(13)21-16-12(3-2-8-20-16)11-6-9-19-10-7-11/h1-5,8,11,19H,6-7,9-10H2 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 33 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]nisoxetine from human NET by scintillation proximity assay |
Bioorg Med Chem Lett 21: 865-8 (2011)
Article DOI: 10.1016/j.bmcl.2010.11.066 BindingDB Entry DOI: 10.7270/Q2HT2PK6 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50333429
(3-(2-phenoxyphenoxy)azetidine | CHEMBL1645596)Show InChI InChI=1S/C15H15NO2/c1-2-6-12(7-3-1)17-14-8-4-5-9-15(14)18-13-10-16-11-13/h1-9,13,16H,10-11H2 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
| Article PubMed
| 57 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by liquid scintillation spectrophotometry |
Bioorg Med Chem Lett 21: 865-8 (2011)
Article DOI: 10.1016/j.bmcl.2010.11.066 BindingDB Entry DOI: 10.7270/Q2HT2PK6 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50333452
(3-(azetidin-3-yloxy)-2-(2-chloro-6-fluorophenoxy)p...)Show InChI InChI=1S/C14H12ClFN2O2/c15-10-3-1-4-11(16)13(10)20-14-12(5-2-6-18-14)19-9-7-17-8-9/h1-6,9,17H,7-8H2 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 64 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by liquid scintillation spectrophotometry |
Bioorg Med Chem Lett 21: 865-8 (2011)
Article DOI: 10.1016/j.bmcl.2010.11.066 BindingDB Entry DOI: 10.7270/Q2HT2PK6 |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50333452
(3-(azetidin-3-yloxy)-2-(2-chloro-6-fluorophenoxy)p...)Show InChI InChI=1S/C14H12ClFN2O2/c15-10-3-1-4-11(16)13(10)20-14-12(5-2-6-18-14)19-9-7-17-8-9/h1-6,9,17H,7-8H2 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 73 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]nisoxetine from human NET by scintillation proximity assay |
Bioorg Med Chem Lett 21: 865-8 (2011)
Article DOI: 10.1016/j.bmcl.2010.11.066 BindingDB Entry DOI: 10.7270/Q2HT2PK6 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50333443
(3-(2-fluoro-6-(2-fluorophenoxy)phenoxy)piperidine ...)Show InChI InChI=1S/C17H17F2NO2/c18-13-6-1-2-8-15(13)22-16-9-3-7-14(19)17(16)21-12-5-4-10-20-11-12/h1-3,6-9,12,20H,4-5,10-11H2 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by liquid scintillation spectrophotometry |
Bioorg Med Chem Lett 21: 865-8 (2011)
Article DOI: 10.1016/j.bmcl.2010.11.066 BindingDB Entry DOI: 10.7270/Q2HT2PK6 |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50333438
(3-(2-(2,3-dichlorophenoxy)-6-fluorophenoxy)azetidi...)Show InChI InChI=1S/C15H12Cl2FNO2/c16-10-3-1-5-12(14(10)17)21-13-6-2-4-11(18)15(13)20-9-7-19-8-9/h1-6,9,19H,7-8H2 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 94 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]citalopram from human SERT by scintillation proximity assay |
Bioorg Med Chem Lett 21: 865-8 (2011)
Article DOI: 10.1016/j.bmcl.2010.11.066 BindingDB Entry DOI: 10.7270/Q2HT2PK6 |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50333450
((R)-3-(2-(2-chloro-6-fluorophenoxy)-6-fluorophenox...)Show InChI InChI=1S/C16H14ClF2NO2/c17-11-3-1-4-12(18)15(11)22-14-6-2-5-13(19)16(14)21-10-7-8-20-9-10/h1-6,10,20H,7-9H2/t10-/m1/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 110 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]nisoxetine from human NET by scintillation proximity assay |
Bioorg Med Chem Lett 21: 865-8 (2011)
Article DOI: 10.1016/j.bmcl.2010.11.066 BindingDB Entry DOI: 10.7270/Q2HT2PK6 |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50333434
(3-(2-fluoro-6-(2-fluoro-6-methylphenoxy)phenoxy)az...)Show InChI InChI=1S/C16H15F2NO2/c1-10-4-2-5-12(17)15(10)21-14-7-3-6-13(18)16(14)20-11-8-19-9-11/h2-7,11,19H,8-9H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 116 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]nisoxetine from human NET by scintillation proximity assay |
Bioorg Med Chem Lett 21: 865-8 (2011)
Article DOI: 10.1016/j.bmcl.2010.11.066 BindingDB Entry DOI: 10.7270/Q2HT2PK6 |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50333433
(3-(2-(2-chloro-6-fluorophenoxy)-6-fluorophenoxy)az...)Show InChI InChI=1S/C15H12ClF2NO2/c16-10-3-1-4-11(17)14(10)21-13-6-2-5-12(18)15(13)20-9-7-19-8-9/h1-6,9,19H,7-8H2 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 138 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]nisoxetine from human NET by scintillation proximity assay |
Bioorg Med Chem Lett 21: 865-8 (2011)
Article DOI: 10.1016/j.bmcl.2010.11.066 BindingDB Entry DOI: 10.7270/Q2HT2PK6 |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50333436
(3-(2-(2,6-dichlorophenoxy)-6-fluorophenoxy)azetidi...)Show InChI InChI=1S/C15H12Cl2FNO2/c16-10-3-1-4-11(17)14(10)21-13-6-2-5-12(18)15(13)20-9-7-19-8-9/h1-6,9,19H,7-8H2 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 164 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]nisoxetine from human NET by scintillation proximity assay |
Bioorg Med Chem Lett 21: 865-8 (2011)
Article DOI: 10.1016/j.bmcl.2010.11.066 BindingDB Entry DOI: 10.7270/Q2HT2PK6 |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50333446
(3-(2-(2-chlorophenoxy)-6-fluorophenoxy)pyrrolidine...)Show InChI InChI=1S/C16H15ClFNO2/c17-12-4-1-2-6-14(12)21-15-7-3-5-13(18)16(15)20-11-8-9-19-10-11/h1-7,11,19H,8-10H2 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 192 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]nisoxetine from human NET by scintillation proximity assay |
Bioorg Med Chem Lett 21: 865-8 (2011)
Article DOI: 10.1016/j.bmcl.2010.11.066 BindingDB Entry DOI: 10.7270/Q2HT2PK6 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50333444
(3-(2-(2-fluorophenoxy)phenoxy)pyrrolidine | CHEMBL...)Show InChI InChI=1S/C16H16FNO2/c17-13-5-1-2-6-14(13)20-16-8-4-3-7-15(16)19-12-9-10-18-11-12/h1-8,12,18H,9-11H2 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 193 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by liquid scintillation spectrophotometry |
Bioorg Med Chem Lett 21: 865-8 (2011)
Article DOI: 10.1016/j.bmcl.2010.11.066 BindingDB Entry DOI: 10.7270/Q2HT2PK6 |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50309519
(2-(2-chloro-6-fluorophenoxy)-3-(piperidin-4-yl)pyr...)Show InChI InChI=1S/C16H16ClFN2O/c17-13-4-1-5-14(18)15(13)21-16-12(3-2-8-20-16)11-6-9-19-10-7-11/h1-5,8,11,19H,6-7,9-10H2 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 194 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]citalopram from human SERT by scintillation proximity assay |
Bioorg Med Chem Lett 21: 865-8 (2011)
Article DOI: 10.1016/j.bmcl.2010.11.066 BindingDB Entry DOI: 10.7270/Q2HT2PK6 |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50333432
(3-(2-(2-chlorophenoxy)-6-fluorophenoxy)azetidine |...)Show InChI InChI=1S/C15H13ClFNO2/c16-11-4-1-2-6-13(11)20-14-7-3-5-12(17)15(14)19-10-8-18-9-10/h1-7,10,18H,8-9H2 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 198 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]nisoxetine from human NET by scintillation proximity assay |
Bioorg Med Chem Lett 21: 865-8 (2011)
Article DOI: 10.1016/j.bmcl.2010.11.066 BindingDB Entry DOI: 10.7270/Q2HT2PK6 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50333451
(2-(2-chloro-6-fluorophenoxy)-3-(pyrrolidin-3-yloxy...)Show InChI InChI=1S/C15H14ClFN2O2/c16-11-3-1-4-12(17)14(11)21-15-13(5-2-7-19-15)20-10-6-8-18-9-10/h1-5,7,10,18H,6,8-9H2 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 203 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by liquid scintillation spectrophotometry |
Bioorg Med Chem Lett 21: 865-8 (2011)
Article DOI: 10.1016/j.bmcl.2010.11.066 BindingDB Entry DOI: 10.7270/Q2HT2PK6 |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50333441
(4-(2-(2-chloro-6-fluorophenoxy)-6-fluorophenoxy)pi...)Show InChI InChI=1S/C17H16ClF2NO2/c18-12-3-1-4-13(19)16(12)23-15-6-2-5-14(20)17(15)22-11-7-9-21-10-8-11/h1-6,11,21H,7-10H2 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 218 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]nisoxetine from human NET by scintillation proximity assay |
Bioorg Med Chem Lett 21: 865-8 (2011)
Article DOI: 10.1016/j.bmcl.2010.11.066 BindingDB Entry DOI: 10.7270/Q2HT2PK6 |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50333448
(3-(2-(2-chloro-6-fluorophenoxy)-6-fluorophenoxy)py...)Show InChI InChI=1S/C16H14ClF2NO2/c17-11-3-1-4-12(18)15(11)22-14-6-2-5-13(19)16(14)21-10-7-8-20-9-10/h1-6,10,20H,7-9H2 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 226 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]nisoxetine from human NET by scintillation proximity assay |
Bioorg Med Chem Lett 21: 865-8 (2011)
Article DOI: 10.1016/j.bmcl.2010.11.066 BindingDB Entry DOI: 10.7270/Q2HT2PK6 |
More data for this Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50309505
(4-(2-fluoro-6-(2-fluorophenoxy)phenyl)piperidine |...)Show InChI InChI=1S/C17H17F2NO/c18-13-4-1-2-6-15(13)21-16-7-3-5-14(19)17(16)12-8-10-20-11-9-12/h1-7,12,20H,8-11H2 | NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 278 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]WIN-35,428 from human DAT by scintillation proximity assay |
Bioorg Med Chem Lett 21: 865-8 (2011)
Article DOI: 10.1016/j.bmcl.2010.11.066 BindingDB Entry DOI: 10.7270/Q2HT2PK6 |
More data for this Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50333438
(3-(2-(2,3-dichlorophenoxy)-6-fluorophenoxy)azetidi...)Show InChI InChI=1S/C15H12Cl2FNO2/c16-10-3-1-5-12(14(10)17)21-13-6-2-4-11(18)15(13)20-9-7-19-8-9/h1-6,9,19H,7-8H2 | NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 312 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]WIN-35,428 from human DAT by scintillation proximity assay |
Bioorg Med Chem Lett 21: 865-8 (2011)
Article DOI: 10.1016/j.bmcl.2010.11.066 BindingDB Entry DOI: 10.7270/Q2HT2PK6 |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50333442
(4-(2-fluoro-6-(2-fluoro-6-methylphenoxy)phenoxy)pi...)Show InChI InChI=1S/C18H19F2NO2/c1-12-4-2-5-14(19)17(12)23-16-7-3-6-15(20)18(16)22-13-8-10-21-11-9-13/h2-7,13,21H,8-11H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 323 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]nisoxetine from human NET by scintillation proximity assay |
Bioorg Med Chem Lett 21: 865-8 (2011)
Article DOI: 10.1016/j.bmcl.2010.11.066 BindingDB Entry DOI: 10.7270/Q2HT2PK6 |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50333447
(3-(2-fluoro-6-(2-fluoro-6-methylphenoxy)phenoxy)py...)Show InChI InChI=1S/C17H17F2NO2/c1-11-4-2-5-13(18)16(11)22-15-7-3-6-14(19)17(15)21-12-8-9-20-10-12/h2-7,12,20H,8-10H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 328 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]nisoxetine from human NET by scintillation proximity assay |
Bioorg Med Chem Lett 21: 865-8 (2011)
Article DOI: 10.1016/j.bmcl.2010.11.066 BindingDB Entry DOI: 10.7270/Q2HT2PK6 |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50333438
(3-(2-(2,3-dichlorophenoxy)-6-fluorophenoxy)azetidi...)Show InChI InChI=1S/C15H12Cl2FNO2/c16-10-3-1-5-12(14(10)17)21-13-6-2-4-11(18)15(13)20-9-7-19-8-9/h1-6,9,19H,7-8H2 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 374 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]nisoxetine from human NET by scintillation proximity assay |
Bioorg Med Chem Lett 21: 865-8 (2011)
Article DOI: 10.1016/j.bmcl.2010.11.066 BindingDB Entry DOI: 10.7270/Q2HT2PK6 |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50333437
(3-(2-(2-chloro-6-methylphenoxy)-6-fluorophenoxy)az...)Show InChI InChI=1S/C16H15ClFNO2/c1-10-4-2-5-12(17)15(10)21-14-7-3-6-13(18)16(14)20-11-8-19-9-11/h2-7,11,19H,8-9H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 433 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]nisoxetine from human NET by scintillation proximity assay |
Bioorg Med Chem Lett 21: 865-8 (2011)
Article DOI: 10.1016/j.bmcl.2010.11.066 BindingDB Entry DOI: 10.7270/Q2HT2PK6 |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50333435
(3-(2-(2,6-difluorophenoxy)-6-fluorophenoxy)azetidi...)Show InChI InChI=1S/C15H12F3NO2/c16-10-3-1-4-11(17)14(10)21-13-6-2-5-12(18)15(13)20-9-7-19-8-9/h1-6,9,19H,7-8H2 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 482 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]nisoxetine from human NET by scintillation proximity assay |
Bioorg Med Chem Lett 21: 865-8 (2011)
Article DOI: 10.1016/j.bmcl.2010.11.066 BindingDB Entry DOI: 10.7270/Q2HT2PK6 |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50333440
(4-(2-fluoro-6-(2-fluorophenoxy)phenoxy)piperidine ...)Show InChI InChI=1S/C17H17F2NO2/c18-13-4-1-2-6-15(13)22-16-7-3-5-14(19)17(16)21-12-8-10-20-11-9-12/h1-7,12,20H,8-11H2 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 489 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]nisoxetine from human NET by scintillation proximity assay |
Bioorg Med Chem Lett 21: 865-8 (2011)
Article DOI: 10.1016/j.bmcl.2010.11.066 BindingDB Entry DOI: 10.7270/Q2HT2PK6 |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50333431
(3-(2-fluoro-6-(2-fluorophenoxy)phenoxy)azetidine |...)Show InChI InChI=1S/C15H13F2NO2/c16-11-4-1-2-6-13(11)20-14-7-3-5-12(17)15(14)19-10-8-18-9-10/h1-7,10,18H,8-9H2 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 507 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]nisoxetine from human NET by scintillation proximity assay |
Bioorg Med Chem Lett 21: 865-8 (2011)
Article DOI: 10.1016/j.bmcl.2010.11.066 BindingDB Entry DOI: 10.7270/Q2HT2PK6 |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50333430
(3-(2-(2-fluorophenoxy)phenoxy)azetidine | CHEMBL16...)Show InChI InChI=1S/C15H14FNO2/c16-12-5-1-2-6-13(12)19-15-8-4-3-7-14(15)18-11-9-17-10-11/h1-8,11,17H,9-10H2 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 528 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]nisoxetine from human NET by scintillation proximity assay |
Bioorg Med Chem Lett 21: 865-8 (2011)
Article DOI: 10.1016/j.bmcl.2010.11.066 BindingDB Entry DOI: 10.7270/Q2HT2PK6 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50333439
(4-(2-(2-fluorophenoxy)phenoxy)piperidine | CHEMBL1...)Show InChI InChI=1S/C17H18FNO2/c18-14-5-1-2-6-15(14)21-17-8-4-3-7-16(17)20-13-9-11-19-12-10-13/h1-8,13,19H,9-12H2 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 693 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by liquid scintillation spectrophotometry |
Bioorg Med Chem Lett 21: 865-8 (2011)
Article DOI: 10.1016/j.bmcl.2010.11.066 BindingDB Entry DOI: 10.7270/Q2HT2PK6 |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50333439
(4-(2-(2-fluorophenoxy)phenoxy)piperidine | CHEMBL1...)Show InChI InChI=1S/C17H18FNO2/c18-14-5-1-2-6-15(14)21-17-8-4-3-7-16(17)20-13-9-11-19-12-10-13/h1-8,13,19H,9-12H2 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]nisoxetine from human NET by scintillation proximity assay |
Bioorg Med Chem Lett 21: 865-8 (2011)
Article DOI: 10.1016/j.bmcl.2010.11.066 BindingDB Entry DOI: 10.7270/Q2HT2PK6 |
More data for this Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50333449
((S)-3-(2-(2-chloro-6-fluorophenoxy)-6-fluorophenox...)Show InChI InChI=1S/C16H14ClF2NO2/c17-11-3-1-4-12(18)15(11)22-14-6-2-5-13(19)16(14)21-10-7-8-20-9-10/h1-6,10,20H,7-9H2/t10-/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.01E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]nisoxetine from human NET by scintillation proximity assay |
Bioorg Med Chem Lett 21: 865-8 (2011)
Article DOI: 10.1016/j.bmcl.2010.11.066 BindingDB Entry DOI: 10.7270/Q2HT2PK6 |
More data for this Ligand-Target Pair | |