Found 42 hits Enz. Inhib. hit(s) with all data for entry = 50040196 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
(Homo sapiens (Human)) | BDBM50390812
(CHEMBL2069321)Show InChI InChI=1S/C18H15ClN4O2/c1-10-17-22-21-16-14(8-11(24-2)9-15(16)25-3)23(17)18(20-10)12-6-4-5-7-13(12)19/h4-9H,1-3H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
MMDB
PC cid
PC sid
PDB
UniChem
Similars
| PDB
Article
PubMed
| n/a | n/a | 0.280 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant PDE10A-catalyzed cAMP hydrolysis |
Bioorg Med Chem Lett 22: 5876-84 (2012)
Article DOI: 10.1016/j.bmcl.2012.07.076
BindingDB Entry DOI: 10.7270/Q2FB5413 |
More data for this
Ligand-Target Pair | 
3D Structure (crystal) |
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
(Homo sapiens (Human)) | BDBM50390818
(CHEMBL2070655)Show SMILES COc1cc(cc2c1nnc1c(C)nc(-c3ccccc3Cl)n21)N1CCOCC1 Show InChI InChI=1S/C21H20ClN5O2/c1-13-20-25-24-19-17(27(20)21(23-13)15-5-3-4-6-16(15)22)11-14(12-18(19)28-2)26-7-9-29-10-8-26/h3-6,11-12H,7-10H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.850 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant PDE10A-catalyzed cAMP hydrolysis |
Bioorg Med Chem Lett 22: 5876-84 (2012)
Article DOI: 10.1016/j.bmcl.2012.07.076
BindingDB Entry DOI: 10.7270/Q2FB5413 |
More data for this
Ligand-Target Pair | |
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
(Homo sapiens (Human)) | BDBM50390834
(CHEMBL2070651)Show InChI InChI=1S/C18H17N5O2/c1-10-13(6-5-7-19-10)18-20-11(2)17-22-21-16-14(23(17)18)8-12(24-3)9-15(16)25-4/h5-9H,1-4H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.48 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant PDE10A-catalyzed cAMP hydrolysis |
Bioorg Med Chem Lett 22: 5876-84 (2012)
Article DOI: 10.1016/j.bmcl.2012.07.076
BindingDB Entry DOI: 10.7270/Q2FB5413 |
More data for this
Ligand-Target Pair | |
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
(Homo sapiens (Human)) | BDBM50390829
(CHEMBL2070666)Show SMILES COc1cc(cc2c1nnc1c(C)nc(-c3ccncc3C)n21)C(F)(F)F Show InChI InChI=1S/C18H14F3N5O/c1-9-8-22-5-4-12(9)17-23-10(2)16-25-24-15-13(26(16)17)6-11(18(19,20)21)7-14(15)27-3/h4-8H,1-3H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.48 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant PDE10A-catalyzed cAMP hydrolysis |
Bioorg Med Chem Lett 22: 5876-84 (2012)
Article DOI: 10.1016/j.bmcl.2012.07.076
BindingDB Entry DOI: 10.7270/Q2FB5413 |
More data for this
Ligand-Target Pair | |
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
(Homo sapiens (Human)) | BDBM50390817
(CHEMBL2070654)Show SMILES COc1cc(cc2c1nnc1c(C)nc(-c3ccccc3C)n21)N1CCOCC1 Show InChI InChI=1S/C22H23N5O2/c1-14-6-4-5-7-17(14)22-23-15(2)21-25-24-20-18(27(21)22)12-16(13-19(20)28-3)26-8-10-29-11-9-26/h4-7,12-13H,8-11H2,1-3H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.53 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant PDE10A-catalyzed cAMP hydrolysis |
Bioorg Med Chem Lett 22: 5876-84 (2012)
Article DOI: 10.1016/j.bmcl.2012.07.076
BindingDB Entry DOI: 10.7270/Q2FB5413 |
More data for this
Ligand-Target Pair | |
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
(Homo sapiens (Human)) | BDBM50390827
(CHEMBL2070664)Show InChI InChI=1S/C16H13FN4OS/c1-8-4-5-23-14(8)16-18-9(2)15-20-19-13-11(21(15)16)6-10(17)7-12(13)22-3/h4-7H,1-3H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.65 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant PDE10A-catalyzed cAMP hydrolysis |
Bioorg Med Chem Lett 22: 5876-84 (2012)
Article DOI: 10.1016/j.bmcl.2012.07.076
BindingDB Entry DOI: 10.7270/Q2FB5413 |
More data for this
Ligand-Target Pair | |
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
(Homo sapiens (Human)) | BDBM50390831
(CHEMBL2070668)Show SMILES COc1cc(cc2c1nnc1c(C)nc(-c3cccc(F)c3C)n21)C(F)(F)F Show InChI InChI=1S/C19H14F4N4O/c1-9-12(5-4-6-13(9)20)18-24-10(2)17-26-25-16-14(27(17)18)7-11(19(21,22)23)8-15(16)28-3/h4-8H,1-3H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.85 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant PDE10A-catalyzed cAMP hydrolysis |
Bioorg Med Chem Lett 22: 5876-84 (2012)
Article DOI: 10.1016/j.bmcl.2012.07.076
BindingDB Entry DOI: 10.7270/Q2FB5413 |
More data for this
Ligand-Target Pair | |
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
(Homo sapiens (Human)) | BDBM50390816
(CHEMBL2070653)Show InChI InChI=1S/C18H17N5O2/c1-10-9-19-6-5-13(10)18-20-11(2)17-22-21-16-14(23(17)18)7-12(24-3)8-15(16)25-4/h5-9H,1-4H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.06 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant PDE10A-catalyzed cAMP hydrolysis |
Bioorg Med Chem Lett 22: 5876-84 (2012)
Article DOI: 10.1016/j.bmcl.2012.07.076
BindingDB Entry DOI: 10.7270/Q2FB5413 |
More data for this
Ligand-Target Pair | |
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
(Homo sapiens (Human)) | BDBM50390811
(CHEMBL2070648)Show InChI InChI=1S/C17H13ClN4O/c1-10-16-21-20-15-13(8-5-9-14(15)23-2)22(16)17(19-10)11-6-3-4-7-12(11)18/h3-9H,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.41 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant PDE10A-catalyzed cAMP hydrolysis |
Bioorg Med Chem Lett 22: 5876-84 (2012)
Article DOI: 10.1016/j.bmcl.2012.07.076
BindingDB Entry DOI: 10.7270/Q2FB5413 |
More data for this
Ligand-Target Pair | |
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
(Homo sapiens (Human)) | BDBM50390810
(CHEMBL2070647)Show InChI InChI=1S/C18H16N4O/c1-11-7-4-5-8-13(11)18-19-12(2)17-21-20-16-14(22(17)18)9-6-10-15(16)23-3/h4-10H,1-3H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant PDE10A-catalyzed cAMP hydrolysis |
Bioorg Med Chem Lett 22: 5876-84 (2012)
Article DOI: 10.1016/j.bmcl.2012.07.076
BindingDB Entry DOI: 10.7270/Q2FB5413 |
More data for this
Ligand-Target Pair | |
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
(Homo sapiens (Human)) | BDBM50390814
(CHEMBL2070650)Show SMILES COc1cc(OC)c2nnc3c(C)nc(-c4ccccc4C(F)(F)F)n3c2c1 Show InChI InChI=1S/C19H15F3N4O2/c1-10-17-25-24-16-14(8-11(27-2)9-15(16)28-3)26(17)18(23-10)12-6-4-5-7-13(12)19(20,21)22/h4-9H,1-3H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.35 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant PDE10A-catalyzed cAMP hydrolysis |
Bioorg Med Chem Lett 22: 5876-84 (2012)
Article DOI: 10.1016/j.bmcl.2012.07.076
BindingDB Entry DOI: 10.7270/Q2FB5413 |
More data for this
Ligand-Target Pair | |
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
(Homo sapiens (Human)) | BDBM50390822
(CHEMBL2070659)Show InChI InChI=1S/C18H14F2N4O/c1-9-12(5-4-6-13(9)20)18-21-10(2)17-23-22-16-14(24(17)18)7-11(19)8-15(16)25-3/h4-8H,1-3H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.55 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant PDE10A-catalyzed cAMP hydrolysis |
Bioorg Med Chem Lett 22: 5876-84 (2012)
Article DOI: 10.1016/j.bmcl.2012.07.076
BindingDB Entry DOI: 10.7270/Q2FB5413 |
More data for this
Ligand-Target Pair | |
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
(Homo sapiens (Human)) | BDBM50390819
(CHEMBL2070656)Show SMILES COc1cc(cc2c1nnc1c(C)nc(-c3ccncc3C)n21)N1CCOCC1 Show InChI InChI=1S/C21H22N6O2/c1-13-12-22-5-4-16(13)21-23-14(2)20-25-24-19-17(27(20)21)10-15(11-18(19)28-3)26-6-8-29-9-7-26/h4-5,10-12H,6-9H2,1-3H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.99 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant PDE10A-catalyzed cAMP hydrolysis |
Bioorg Med Chem Lett 22: 5876-84 (2012)
Article DOI: 10.1016/j.bmcl.2012.07.076
BindingDB Entry DOI: 10.7270/Q2FB5413 |
More data for this
Ligand-Target Pair | |
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
(Homo sapiens (Human)) | BDBM50390815
(CHEMBL2070652)Show InChI InChI=1S/C18H17N5O2/c1-10-5-6-19-9-13(10)18-20-11(2)17-22-21-16-14(23(17)18)7-12(24-3)8-15(16)25-4/h5-9H,1-4H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.16 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant PDE10A-catalyzed cAMP hydrolysis |
Bioorg Med Chem Lett 22: 5876-84 (2012)
Article DOI: 10.1016/j.bmcl.2012.07.076
BindingDB Entry DOI: 10.7270/Q2FB5413 |
More data for this
Ligand-Target Pair | |
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
(Homo sapiens (Human)) | BDBM50390830
(CHEMBL2070667)Show SMILES COc1cc(cc2c1nnc1c(C)nc(-c3cnccc3C)n21)C(F)(F)F Show InChI InChI=1S/C18H14F3N5O/c1-9-4-5-22-8-12(9)17-23-10(2)16-25-24-15-13(26(16)17)6-11(18(19,20)21)7-14(15)27-3/h4-8H,1-3H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.11 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant PDE10A-catalyzed cAMP hydrolysis |
Bioorg Med Chem Lett 22: 5876-84 (2012)
Article DOI: 10.1016/j.bmcl.2012.07.076
BindingDB Entry DOI: 10.7270/Q2FB5413 |
More data for this
Ligand-Target Pair | |
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
(Homo sapiens (Human)) | BDBM50390813
(CHEMBL2070649)Show InChI InChI=1S/C19H18N4O2/c1-11-7-5-6-8-14(11)19-20-12(2)18-22-21-17-15(23(18)19)9-13(24-3)10-16(17)25-4/h5-10H,1-4H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.13 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant PDE10A-catalyzed cAMP hydrolysis |
Bioorg Med Chem Lett 22: 5876-84 (2012)
Article DOI: 10.1016/j.bmcl.2012.07.076
BindingDB Entry DOI: 10.7270/Q2FB5413 |
More data for this
Ligand-Target Pair | |
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
(Homo sapiens (Human)) | BDBM50390820
(CHEMBL2070657)Show InChI InChI=1S/C18H15FN4O2/c1-10-17-22-21-16-13(8-11(19)9-15(16)25-3)23(17)18(20-10)12-6-4-5-7-14(12)24-2/h4-9H,1-3H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6.53 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant PDE10A-catalyzed cAMP hydrolysis |
Bioorg Med Chem Lett 22: 5876-84 (2012)
Article DOI: 10.1016/j.bmcl.2012.07.076
BindingDB Entry DOI: 10.7270/Q2FB5413 |
More data for this
Ligand-Target Pair | |
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
(Homo sapiens (Human)) | BDBM50390835
(CHEMBL2070669)Show SMILES COc1cc(OC(F)F)cc2c1nnc1c(C)nc(-c3ccncc3C)n21 Show InChI InChI=1S/C18H15F2N5O2/c1-9-8-21-5-4-12(9)17-22-10(2)16-24-23-15-13(25(16)17)6-11(27-18(19)20)7-14(15)26-3/h4-8,18H,1-3H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant PDE10A-catalyzed cAMP hydrolysis |
Bioorg Med Chem Lett 22: 5876-84 (2012)
Article DOI: 10.1016/j.bmcl.2012.07.076
BindingDB Entry DOI: 10.7270/Q2FB5413 |
More data for this
Ligand-Target Pair | |
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
(Homo sapiens (Human)) | BDBM50390824
(CHEMBL2070661)Show InChI InChI=1S/C17H14FN5O/c1-9-8-19-5-4-12(9)17-20-10(2)16-22-21-15-13(23(16)17)6-11(18)7-14(15)24-3/h4-8H,1-3H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant PDE10A-catalyzed cAMP hydrolysis |
Bioorg Med Chem Lett 22: 5876-84 (2012)
Article DOI: 10.1016/j.bmcl.2012.07.076
BindingDB Entry DOI: 10.7270/Q2FB5413 |
More data for this
Ligand-Target Pair | |
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
(Homo sapiens (Human)) | BDBM50390825
(CHEMBL2070662)Show InChI InChI=1S/C17H14FN5O/c1-9-12(5-4-6-19-9)17-20-10(2)16-22-21-15-13(23(16)17)7-11(18)8-14(15)24-3/h4-8H,1-3H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7.84 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant PDE10A-catalyzed cAMP hydrolysis |
Bioorg Med Chem Lett 22: 5876-84 (2012)
Article DOI: 10.1016/j.bmcl.2012.07.076
BindingDB Entry DOI: 10.7270/Q2FB5413 |
More data for this
Ligand-Target Pair | |
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
(Homo sapiens (Human)) | BDBM50390832
(CHEMBL2070670)Show InChI InChI=1S/C18H15FN4O2/c1-10-17-22-21-16-13(19)8-11(24-2)9-14(16)23(17)18(20-10)12-6-4-5-7-15(12)25-3/h4-9H,1-3H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 8.33 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant PDE10A-catalyzed cAMP hydrolysis |
Bioorg Med Chem Lett 22: 5876-84 (2012)
Article DOI: 10.1016/j.bmcl.2012.07.076
BindingDB Entry DOI: 10.7270/Q2FB5413 |
More data for this
Ligand-Target Pair | |
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
(Homo sapiens (Human)) | BDBM50390821
(CHEMBL2070658)Show InChI InChI=1S/C18H15FN4O2/c1-10-17-22-21-16-14(8-12(19)9-15(16)25-3)23(17)18(20-10)11-5-4-6-13(7-11)24-2/h4-9H,1-3H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 9.11 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant PDE10A-catalyzed cAMP hydrolysis |
Bioorg Med Chem Lett 22: 5876-84 (2012)
Article DOI: 10.1016/j.bmcl.2012.07.076
BindingDB Entry DOI: 10.7270/Q2FB5413 |
More data for this
Ligand-Target Pair | |
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
(Homo sapiens (Human)) | BDBM50390833
(CHEMBL2070671)Show InChI InChI=1S/C16H13FN4OS/c1-8-4-5-23-14(8)16-18-9(2)15-20-19-13-11(17)6-10(22-3)7-12(13)21(15)16/h4-7H,1-3H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 9.43 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant PDE10A-catalyzed cAMP hydrolysis |
Bioorg Med Chem Lett 22: 5876-84 (2012)
Article DOI: 10.1016/j.bmcl.2012.07.076
BindingDB Entry DOI: 10.7270/Q2FB5413 |
More data for this
Ligand-Target Pair | |
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
(Homo sapiens (Human)) | BDBM50390804
(CHEMBL2070641)Show InChI InChI=1S/C17H14FN5O2/c1-9-15-22-21-13-6-7-14(25-3)20-17(13)23(15)16(19-9)11-8-10(24-2)4-5-12(11)18/h4-8H,1-3H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 9.83 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant PDE10A-catalyzed cAMP hydrolysis |
Bioorg Med Chem Lett 22: 5876-84 (2012)
Article DOI: 10.1016/j.bmcl.2012.07.076
BindingDB Entry DOI: 10.7270/Q2FB5413 |
More data for this
Ligand-Target Pair | |
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
(Homo sapiens (Human)) | BDBM50390808
(CHEMBL2070645)Show InChI InChI=1S/C16H14N6O/c1-9-8-17-6-4-11(9)15-19-10(2)14-21-20-13-12(23-3)5-7-18-16(13)22(14)15/h4-8H,1-3H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 10.1 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant PDE10A-catalyzed cAMP hydrolysis |
Bioorg Med Chem Lett 22: 5876-84 (2012)
Article DOI: 10.1016/j.bmcl.2012.07.076
BindingDB Entry DOI: 10.7270/Q2FB5413 |
More data for this
Ligand-Target Pair | |
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
(Homo sapiens (Human)) | BDBM50390828
(CHEMBL2070665)Show InChI InChI=1S/C16H14FN5OS/c1-7-14(24-9(3)18-7)16-19-8(2)15-21-20-13-11(22(15)16)5-10(17)6-12(13)23-4/h5-6H,1-4H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 11.7 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant PDE10A-catalyzed cAMP hydrolysis |
Bioorg Med Chem Lett 22: 5876-84 (2012)
Article DOI: 10.1016/j.bmcl.2012.07.076
BindingDB Entry DOI: 10.7270/Q2FB5413 |
More data for this
Ligand-Target Pair | |
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
(Homo sapiens (Human)) | BDBM50390809
(CHEMBL2070646)Show InChI InChI=1S/C16H14N6O/c1-9-11(5-4-7-17-9)15-19-10(2)14-21-20-13-12(23-3)6-8-18-16(13)22(14)15/h4-8H,1-3H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 12.4 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant PDE10A-catalyzed cAMP hydrolysis |
Bioorg Med Chem Lett 22: 5876-84 (2012)
Article DOI: 10.1016/j.bmcl.2012.07.076
BindingDB Entry DOI: 10.7270/Q2FB5413 |
More data for this
Ligand-Target Pair | |
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
(Homo sapiens (Human)) | BDBM50390802
(CHEMBL2070631)Show InChI InChI=1S/C16H11ClFN5O/c1-8-14-22-21-12-5-6-13(24-2)20-16(12)23(14)15(19-8)10-4-3-9(18)7-11(10)17/h3-7H,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 13.1 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant PDE10A-catalyzed cAMP hydrolysis |
Bioorg Med Chem Lett 22: 5876-84 (2012)
Article DOI: 10.1016/j.bmcl.2012.07.076
BindingDB Entry DOI: 10.7270/Q2FB5413 |
More data for this
Ligand-Target Pair | |
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
(Homo sapiens (Human)) | BDBM50390800
(CHEMBL2070639)Show InChI InChI=1S/C16H12ClN5O/c1-9-14-21-20-12-7-8-13(23-2)19-16(12)22(14)15(18-9)10-5-3-4-6-11(10)17/h3-8H,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 13.1 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant PDE10A-catalyzed cAMP hydrolysis |
Bioorg Med Chem Lett 22: 5876-84 (2012)
Article DOI: 10.1016/j.bmcl.2012.07.076
BindingDB Entry DOI: 10.7270/Q2FB5413 |
More data for this
Ligand-Target Pair | |
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
(Homo sapiens (Human)) | BDBM50390826
(CHEMBL2070663)Show SMILES COc1cc(F)cc2c1nnc1c(C)nc(-c3c(C)nn(C)c3C)n21 |(5.87,4.24,;4.53,3.46,;4.54,1.92,;3.21,1.15,;3.21,-.39,;1.87,-1.16,;4.54,-1.16,;5.87,-.4,;5.87,1.16,;7.21,1.94,;8.56,1.15,;8.56,-.4,;9.7,-1.44,;11.21,-1.13,;9.06,-2.85,;7.53,-2.68,;6.61,-3.91,;5.07,-3.89,;4.18,-2.64,;4.58,-5.35,;5.81,-6.27,;5.8,-7.81,;7.07,-5.38,;8.53,-5.87,;7.22,-1.17,)| Show InChI InChI=1S/C17H17FN6O/c1-8-14(10(3)23(4)22-8)17-19-9(2)16-21-20-15-12(24(16)17)6-11(18)7-13(15)25-5/h6-7H,1-5H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 13.1 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant PDE10A-catalyzed cAMP hydrolysis |
Bioorg Med Chem Lett 22: 5876-84 (2012)
Article DOI: 10.1016/j.bmcl.2012.07.076
BindingDB Entry DOI: 10.7270/Q2FB5413 |
More data for this
Ligand-Target Pair | |
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
(Homo sapiens (Human)) | BDBM50390801
(CHEMBL2070640)Show InChI InChI=1S/C16H11Cl2N5O/c1-8-14-22-21-12-5-6-13(24-2)20-16(12)23(14)15(19-8)10-4-3-9(17)7-11(10)18/h3-7H,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant PDE10A-catalyzed cAMP hydrolysis |
Bioorg Med Chem Lett 22: 5876-84 (2012)
Article DOI: 10.1016/j.bmcl.2012.07.076
BindingDB Entry DOI: 10.7270/Q2FB5413 |
More data for this
Ligand-Target Pair | |
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
(Homo sapiens (Human)) | BDBM50390823
(CHEMBL2070660)Show InChI InChI=1S/C17H14FN5O/c1-9-4-5-19-8-12(9)17-20-10(2)16-22-21-15-13(23(16)17)6-11(18)7-14(15)24-3/h4-8H,1-3H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 25.4 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant PDE10A-catalyzed cAMP hydrolysis |
Bioorg Med Chem Lett 22: 5876-84 (2012)
Article DOI: 10.1016/j.bmcl.2012.07.076
BindingDB Entry DOI: 10.7270/Q2FB5413 |
More data for this
Ligand-Target Pair | |
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
(Homo sapiens (Human)) | BDBM50390807
(CHEMBL2070644)Show InChI InChI=1S/C16H14N6O/c1-9-4-6-17-8-11(9)15-19-10(2)14-21-20-13-12(23-3)5-7-18-16(13)22(14)15/h4-8H,1-3H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 42.4 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant PDE10A-catalyzed cAMP hydrolysis |
Bioorg Med Chem Lett 22: 5876-84 (2012)
Article DOI: 10.1016/j.bmcl.2012.07.076
BindingDB Entry DOI: 10.7270/Q2FB5413 |
More data for this
Ligand-Target Pair | |
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
(Homo sapiens (Human)) | BDBM50390799
(CHEMBL2070633)Show InChI InChI=1S/C17H14FN5O/c1-9-8-11(18)4-5-12(9)16-19-10(2)15-22-21-13-6-7-14(24-3)20-17(13)23(15)16/h4-8H,1-3H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 45.9 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant PDE10A-catalyzed cAMP hydrolysis |
Bioorg Med Chem Lett 22: 5876-84 (2012)
Article DOI: 10.1016/j.bmcl.2012.07.076
BindingDB Entry DOI: 10.7270/Q2FB5413 |
More data for this
Ligand-Target Pair | |
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
(Homo sapiens (Human)) | BDBM50390798
(CHEMBL2070634)Show InChI InChI=1S/C17H15N5O/c1-10-6-4-5-7-12(10)16-18-11(2)15-21-20-13-8-9-14(23-3)19-17(13)22(15)16/h4-9H,1-3H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 47.6 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant PDE10A-catalyzed cAMP hydrolysis |
Bioorg Med Chem Lett 22: 5876-84 (2012)
Article DOI: 10.1016/j.bmcl.2012.07.076
BindingDB Entry DOI: 10.7270/Q2FB5413 |
More data for this
Ligand-Target Pair | |
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
(Homo sapiens (Human)) | BDBM50390837
(CHEMBL2070637)Show InChI InChI=1S/C16H14N6O/c1-9-6-11(8-17-7-9)15-18-10(2)14-21-20-12-4-5-13(23-3)19-16(12)22(14)15/h4-8H,1-3H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 51.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant PDE10A-catalyzed cAMP hydrolysis |
Bioorg Med Chem Lett 22: 5876-84 (2012)
Article DOI: 10.1016/j.bmcl.2012.07.076
BindingDB Entry DOI: 10.7270/Q2FB5413 |
More data for this
Ligand-Target Pair | |
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
(Homo sapiens (Human)) | BDBM50390803
(CHEMBL2070632)Show InChI InChI=1S/C16H11Cl2N5O/c1-8-14-22-21-12-5-6-13(24-2)20-16(12)23(14)15(19-8)10-7-9(17)3-4-11(10)18/h3-7H,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 53.1 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant PDE10A-catalyzed cAMP hydrolysis |
Bioorg Med Chem Lett 22: 5876-84 (2012)
Article DOI: 10.1016/j.bmcl.2012.07.076
BindingDB Entry DOI: 10.7270/Q2FB5413 |
More data for this
Ligand-Target Pair | |
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
(Homo sapiens (Human)) | BDBM50390797
(CHEMBL2070635)Show InChI InChI=1S/C15H14N6OS/c1-7-12(23-9(3)16-7)15-17-8(2)13-20-19-10-5-6-11(22-4)18-14(10)21(13)15/h5-6H,1-4H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 64.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant PDE10A-catalyzed cAMP hydrolysis |
Bioorg Med Chem Lett 22: 5876-84 (2012)
Article DOI: 10.1016/j.bmcl.2012.07.076
BindingDB Entry DOI: 10.7270/Q2FB5413 |
More data for this
Ligand-Target Pair | |
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
(Homo sapiens (Human)) | BDBM50390836
(CHEMBL2070636)Show InChI InChI=1S/C16H14N6O2/c1-9-14-21-20-12-4-5-13(24-3)19-16(12)22(14)15(18-9)10-6-11(23-2)8-17-7-10/h4-8H,1-3H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 91.3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant PDE10A-catalyzed cAMP hydrolysis |
Bioorg Med Chem Lett 22: 5876-84 (2012)
Article DOI: 10.1016/j.bmcl.2012.07.076
BindingDB Entry DOI: 10.7270/Q2FB5413 |
More data for this
Ligand-Target Pair | |
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
(Homo sapiens (Human)) | BDBM50390805
(CHEMBL2070642)Show SMILES CCOc1ccc(F)c(c1)-c1nc(C)c2nnc3ccc(OC)nc3n12 Show InChI InChI=1S/C18H16FN5O2/c1-4-26-11-5-6-13(19)12(9-11)17-20-10(2)16-23-22-14-7-8-15(25-3)21-18(14)24(16)17/h5-9H,4H2,1-3H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 114 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant PDE10A-catalyzed cAMP hydrolysis |
Bioorg Med Chem Lett 22: 5876-84 (2012)
Article DOI: 10.1016/j.bmcl.2012.07.076
BindingDB Entry DOI: 10.7270/Q2FB5413 |
More data for this
Ligand-Target Pair | |
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
(Homo sapiens (Human)) | BDBM50390838
(CHEMBL2070638)Show InChI InChI=1S/C16H14N6O/c1-9-6-7-17-8-11(9)15-18-10(2)14-21-20-12-4-5-13(23-3)19-16(12)22(14)15/h4-8H,1-3H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 388 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant PDE10A-catalyzed cAMP hydrolysis |
Bioorg Med Chem Lett 22: 5876-84 (2012)
Article DOI: 10.1016/j.bmcl.2012.07.076
BindingDB Entry DOI: 10.7270/Q2FB5413 |
More data for this
Ligand-Target Pair | |
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
(Homo sapiens (Human)) | BDBM50390806
(CHEMBL2070643)Show SMILES COc1ccc2nnc3c(C)nc(-c4cc(OC(C)C)ccc4F)n3c2n1 Show InChI InChI=1S/C19H18FN5O2/c1-10(2)27-12-5-6-14(20)13(9-12)18-21-11(3)17-24-23-15-7-8-16(26-4)22-19(15)25(17)18/h5-10H,1-4H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.43E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant PDE10A-catalyzed cAMP hydrolysis |
Bioorg Med Chem Lett 22: 5876-84 (2012)
Article DOI: 10.1016/j.bmcl.2012.07.076
BindingDB Entry DOI: 10.7270/Q2FB5413 |
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Ligand-Target Pair | |
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