Found 92 hits Enz. Inhib. hit(s) with all data for entry = 50043374 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Glucocorticoid receptor
(Homo sapiens (Human)) | BDBM50440105
(CHEMBL2426114)Show SMILES CC(C)(CNS(C)(=O)=O)[C@@H](c1ccccc1)c1ccc2n(ncc2c1)-c1ccc(F)cc1 |r| Show InChI InChI=1S/C25H26FN3O2S/c1-25(2,17-28-32(3,30)31)24(18-7-5-4-6-8-18)19-9-14-23-20(15-19)16-27-29(23)22-12-10-21(26)11-13-22/h4-16,24,28H,17H2,1-3H3/t24-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 0.530 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
Curated by ChEMBL
| Assay Description Binding affinity to glucocorticoid receptor (unknown origin) by fluorescence assay |
Bioorg Med Chem Lett 23: 5448-51 (2013)
Article DOI: 10.1016/j.bmcl.2013.06.085 BindingDB Entry DOI: 10.7270/Q22R3T2S |
More data for this Ligand-Target Pair | |
Glucocorticoid receptor
(Homo sapiens (Human)) | BDBM50440097
(CHEMBL2426118)Show SMILES CC(C)(CNS(=O)(=O)CC(F)(F)F)[C@@H](c1ccccc1)c1ccc2n(ncc2c1)-c1ccc(F)cc1 |r| Show InChI InChI=1S/C26H25F4N3O2S/c1-25(2,16-32-36(34,35)17-26(28,29)30)24(18-6-4-3-5-7-18)19-8-13-23-20(14-19)15-31-33(23)22-11-9-21(27)10-12-22/h3-15,24,32H,16-17H2,1-2H3/t24-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 0.640 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
Curated by ChEMBL
| Assay Description Binding affinity to glucocorticoid receptor (unknown origin) by fluorescence assay |
Bioorg Med Chem Lett 23: 5448-51 (2013)
Article DOI: 10.1016/j.bmcl.2013.06.085 BindingDB Entry DOI: 10.7270/Q22R3T2S |
More data for this Ligand-Target Pair | |
Glucocorticoid receptor
(Homo sapiens (Human)) | BDBM50440104
(CHEMBL2426115)Show SMILES CCS(=O)(=O)NCC(C)(C)[C@@H](c1ccccc1)c1ccc2n(ncc2c1)-c1ccc(F)cc1 |r| Show InChI InChI=1S/C26H28FN3O2S/c1-4-33(31,32)29-18-26(2,3)25(19-8-6-5-7-9-19)20-10-15-24-21(16-20)17-28-30(24)23-13-11-22(27)12-14-23/h5-17,25,29H,4,18H2,1-3H3/t25-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 0.720 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
Curated by ChEMBL
| Assay Description Binding affinity to glucocorticoid receptor (unknown origin) by fluorescence assay |
Bioorg Med Chem Lett 23: 5448-51 (2013)
Article DOI: 10.1016/j.bmcl.2013.06.085 BindingDB Entry DOI: 10.7270/Q22R3T2S |
More data for this Ligand-Target Pair | |
Glucocorticoid receptor
(Homo sapiens (Human)) | BDBM50440096
(CHEMBL2426124)Show SMILES CC(C)(CNC(=O)CC(F)(F)F)[C@@H](c1ccccc1)c1ccc2n(ncc2c1)-c1ccc(F)cc1 |r| Show InChI InChI=1S/C27H25F4N3O/c1-26(2,17-32-24(35)15-27(29,30)31)25(18-6-4-3-5-7-18)19-8-13-23-20(14-19)16-33-34(23)22-11-9-21(28)10-12-22/h3-14,16,25H,15,17H2,1-2H3,(H,32,35)/t25-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 0.810 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
Curated by ChEMBL
| Assay Description Binding affinity to glucocorticoid receptor (unknown origin) by fluorescence assay |
Bioorg Med Chem Lett 23: 5448-51 (2013)
Article DOI: 10.1016/j.bmcl.2013.06.085 BindingDB Entry DOI: 10.7270/Q22R3T2S |
More data for this Ligand-Target Pair | |
Glucocorticoid receptor
(Homo sapiens (Human)) | BDBM50440099
(CHEMBL2426121)Show SMILES CCS(=O)(=O)NCC(C)[C@@H](c1ccccc1)c1ccc2n(ncc2c1)-c1ccc(F)cc1 |r| Show InChI InChI=1S/C25H26FN3O2S/c1-3-32(30,31)28-16-18(2)25(19-7-5-4-6-8-19)20-9-14-24-21(15-20)17-27-29(24)23-12-10-22(26)11-13-23/h4-15,17-18,25,28H,3,16H2,1-2H3/t18?,25-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 0.870 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
Curated by ChEMBL
| Assay Description Binding affinity to glucocorticoid receptor (unknown origin) by fluorescence assay |
Bioorg Med Chem Lett 23: 5448-51 (2013)
Article DOI: 10.1016/j.bmcl.2013.06.085 BindingDB Entry DOI: 10.7270/Q22R3T2S |
More data for this Ligand-Target Pair | |
Glucocorticoid receptor
(Homo sapiens (Human)) | BDBM50440100
(CHEMBL2426120)Show SMILES CC(CNS(C)(=O)=O)[C@@H](c1ccccc1)c1ccc2n(ncc2c1)-c1ccc(F)cc1 |r| Show InChI InChI=1S/C24H24FN3O2S/c1-17(15-27-31(2,29)30)24(18-6-4-3-5-7-18)19-8-13-23-20(14-19)16-26-28(23)22-11-9-21(25)10-12-22/h3-14,16-17,24,27H,15H2,1-2H3/t17?,24-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 0.930 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
Curated by ChEMBL
| Assay Description Binding affinity to glucocorticoid receptor (unknown origin) by fluorescence assay |
Bioorg Med Chem Lett 23: 5448-51 (2013)
Article DOI: 10.1016/j.bmcl.2013.06.085 BindingDB Entry DOI: 10.7270/Q22R3T2S |
More data for this Ligand-Target Pair | |
Glucocorticoid receptor
(Homo sapiens (Human)) | BDBM18207
((1R,2S,10S,11S,13R,14R,15S,17S)-1-fluoro-14,17-dih...)Show SMILES [H][C@@]12C[C@@H](C)[C@](O)(C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]1(F)[C@@]2([H])CCC2=CC(=O)C=C[C@]12C |c:28,t:24| Show InChI InChI=1S/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15+,16+,17+,19+,20+,21+,22+/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| DrugBank PDB Article PubMed
| 1.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
Curated by ChEMBL
| Assay Description Binding affinity to glucocorticoid receptor (unknown origin) by fluorescence assay |
Bioorg Med Chem Lett 23: 5448-51 (2013)
Article DOI: 10.1016/j.bmcl.2013.06.085 BindingDB Entry DOI: 10.7270/Q22R3T2S |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Glucocorticoid receptor
(Homo sapiens (Human)) | BDBM50440102
(CHEMBL2426117)Show SMILES CC(C)(CNS(=O)(=O)C1CC1)[C@@H](c1ccccc1)c1ccc2n(ncc2c1)-c1ccc(F)cc1 |r| Show InChI InChI=1S/C27H28FN3O2S/c1-27(2,18-30-34(32,33)24-13-14-24)26(19-6-4-3-5-7-19)20-8-15-25-21(16-20)17-29-31(25)23-11-9-22(28)10-12-23/h3-12,15-17,24,26,30H,13-14,18H2,1-2H3/t26-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
Curated by ChEMBL
| Assay Description Binding affinity to glucocorticoid receptor (unknown origin) by fluorescence assay |
Bioorg Med Chem Lett 23: 5448-51 (2013)
Article DOI: 10.1016/j.bmcl.2013.06.085 BindingDB Entry DOI: 10.7270/Q22R3T2S |
More data for this Ligand-Target Pair | |
Glucocorticoid receptor
(Homo sapiens (Human)) | BDBM50440101
(CHEMBL2426119)Show SMILES CC(CNS(=O)(=O)CC(F)(F)F)[C@@H](c1ccccc1)c1ccc2n(ncc2c1)-c1ccc(F)cc1 |r| Show InChI InChI=1S/C25H23F4N3O2S/c1-17(14-31-35(33,34)16-25(27,28)29)24(18-5-3-2-4-6-18)19-7-12-23-20(13-19)15-30-32(23)22-10-8-21(26)9-11-22/h2-13,15,17,24,31H,14,16H2,1H3/t17?,24-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
Curated by ChEMBL
| Assay Description Binding affinity to glucocorticoid receptor (unknown origin) by fluorescence assay |
Bioorg Med Chem Lett 23: 5448-51 (2013)
Article DOI: 10.1016/j.bmcl.2013.06.085 BindingDB Entry DOI: 10.7270/Q22R3T2S |
More data for this Ligand-Target Pair | |
Glucocorticoid receptor
(Homo sapiens (Human)) | BDBM50440110
(CHEMBL2426128)Show SMILES CC(C)C[C@@H](c1ccc2n(ncc2c1)-c1ccc(F)cc1)C(C)(C)CNC(=O)CC(F)(F)F |r| Show InChI InChI=1S/C25H29F4N3O/c1-16(2)11-21(24(3,4)15-30-23(33)13-25(27,28)29)17-5-10-22-18(12-17)14-31-32(22)20-8-6-19(26)7-9-20/h5-10,12,14,16,21H,11,13,15H2,1-4H3,(H,30,33)/t21-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
Curated by ChEMBL
| Assay Description Binding affinity to glucocorticoid receptor (unknown origin) by fluorescence assay |
Bioorg Med Chem Lett 23: 5448-51 (2013)
Article DOI: 10.1016/j.bmcl.2013.06.085 BindingDB Entry DOI: 10.7270/Q22R3T2S |
More data for this Ligand-Target Pair | |
Glucocorticoid receptor
(Homo sapiens (Human)) | BDBM50440107
(CHEMBL2426111)Show SMILES CC(C)C[C@@H](c1ccc2n(ncc2c1)-c1ccc(F)cc1)C(C)(C)CNC(=O)NCC(F)(F)F |r| Show InChI InChI=1S/C25H30F4N4O/c1-16(2)11-21(24(3,4)14-30-23(34)31-15-25(27,28)29)17-5-10-22-18(12-17)13-32-33(22)20-8-6-19(26)7-9-20/h5-10,12-13,16,21H,11,14-15H2,1-4H3,(H2,30,31,34)/t21-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
Curated by ChEMBL
| Assay Description Binding affinity to glucocorticoid receptor (unknown origin) by fluorescence assay |
Bioorg Med Chem Lett 23: 5448-51 (2013)
Article DOI: 10.1016/j.bmcl.2013.06.085 BindingDB Entry DOI: 10.7270/Q22R3T2S |
More data for this Ligand-Target Pair | |
Glucocorticoid receptor
(Homo sapiens (Human)) | BDBM50440103
(CHEMBL2426116)Show SMILES CCCS(=O)(=O)NCC(C)(C)[C@@H](c1ccccc1)c1ccc2n(ncc2c1)-c1ccc(F)cc1 |r| Show InChI InChI=1S/C27H30FN3O2S/c1-4-16-34(32,33)30-19-27(2,3)26(20-8-6-5-7-9-20)21-10-15-25-22(17-21)18-29-31(25)24-13-11-23(28)12-14-24/h5-15,17-18,26,30H,4,16,19H2,1-3H3/t26-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
Curated by ChEMBL
| Assay Description Binding affinity to glucocorticoid receptor (unknown origin) by fluorescence assay |
Bioorg Med Chem Lett 23: 5448-51 (2013)
Article DOI: 10.1016/j.bmcl.2013.06.085 BindingDB Entry DOI: 10.7270/Q22R3T2S |
More data for this Ligand-Target Pair | |
Glucocorticoid receptor
(Homo sapiens (Human)) | BDBM50440114
(CHEMBL2426123)Show SMILES CC(C)(CNC(=O)C(F)(F)F)[C@@H](c1ccccc1)c1ccc2n(ncc2c1)-c1ccc(F)cc1 |r| Show InChI InChI=1S/C26H23F4N3O/c1-25(2,16-31-24(34)26(28,29)30)23(17-6-4-3-5-7-17)18-8-13-22-19(14-18)15-32-33(22)21-11-9-20(27)10-12-21/h3-15,23H,16H2,1-2H3,(H,31,34)/t23-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
Curated by ChEMBL
| Assay Description Binding affinity to glucocorticoid receptor (unknown origin) by fluorescence assay |
Bioorg Med Chem Lett 23: 5448-51 (2013)
Article DOI: 10.1016/j.bmcl.2013.06.085 BindingDB Entry DOI: 10.7270/Q22R3T2S |
More data for this Ligand-Target Pair | |
Glucocorticoid receptor
(Homo sapiens (Human)) | BDBM50440112
(CHEMBL2426126)Show SMILES CC(C)(C)CC(=O)NCC(C)(C)[C@@H](c1ccccc1)c1ccc2n(ncc2c1)-c1ccc(F)cc1 |r| Show InChI InChI=1S/C30H34FN3O/c1-29(2,3)18-27(35)32-20-30(4,5)28(21-9-7-6-8-10-21)22-11-16-26-23(17-22)19-33-34(26)25-14-12-24(31)13-15-25/h6-17,19,28H,18,20H2,1-5H3,(H,32,35)/t28-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
Curated by ChEMBL
| Assay Description Binding affinity to glucocorticoid receptor (unknown origin) by fluorescence assay |
Bioorg Med Chem Lett 23: 5448-51 (2013)
Article DOI: 10.1016/j.bmcl.2013.06.085 BindingDB Entry DOI: 10.7270/Q22R3T2S |
More data for this Ligand-Target Pair | |
Glucocorticoid receptor
(Homo sapiens (Human)) | BDBM50440113
(CHEMBL2426125)Show SMILES CC(C)(C)C(=O)NCC(C)(C)[C@@H](c1ccccc1)c1ccc2n(ncc2c1)-c1ccc(F)cc1 |r| Show InChI InChI=1S/C29H32FN3O/c1-28(2,3)27(34)31-19-29(4,5)26(20-9-7-6-8-10-20)21-11-16-25-22(17-21)18-32-33(25)24-14-12-23(30)13-15-24/h6-18,26H,19H2,1-5H3,(H,31,34)/t26-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
Curated by ChEMBL
| Assay Description Binding affinity to glucocorticoid receptor (unknown origin) by fluorescence assay |
Bioorg Med Chem Lett 23: 5448-51 (2013)
Article DOI: 10.1016/j.bmcl.2013.06.085 BindingDB Entry DOI: 10.7270/Q22R3T2S |
More data for this Ligand-Target Pair | |
Glucocorticoid receptor
(Homo sapiens (Human)) | BDBM50440109
(CHEMBL2426109)Show SMILES CC(CNC(=O)CC(F)(F)F)[C@@H](c1ccccc1)c1ccc2n(ncc2c1)-c1ccc(F)cc1 |r| Show InChI InChI=1S/C26H23F4N3O/c1-17(15-31-24(34)14-26(28,29)30)25(18-5-3-2-4-6-18)19-7-12-23-20(13-19)16-32-33(23)22-10-8-21(27)9-11-22/h2-13,16-17,25H,14-15H2,1H3,(H,31,34)/t17?,25-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 2.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
Curated by ChEMBL
| Assay Description Binding affinity to glucocorticoid receptor (unknown origin) by fluorescence assay |
Bioorg Med Chem Lett 23: 5448-51 (2013)
Article DOI: 10.1016/j.bmcl.2013.06.085 BindingDB Entry DOI: 10.7270/Q22R3T2S |
More data for this Ligand-Target Pair | |
Glucocorticoid receptor
(Homo sapiens (Human)) | BDBM50440115
(CHEMBL2426122)Show SMILES CC(=O)NCC(C)(C)[C@@H](c1ccccc1)c1ccc2n(ncc2c1)-c1ccc(F)cc1 |r| Show InChI InChI=1S/C26H26FN3O/c1-18(31)28-17-26(2,3)25(19-7-5-4-6-8-19)20-9-14-24-21(15-20)16-29-30(24)23-12-10-22(27)11-13-23/h4-16,25H,17H2,1-3H3,(H,28,31)/t25-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 2.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
Curated by ChEMBL
| Assay Description Binding affinity to glucocorticoid receptor (unknown origin) by fluorescence assay |
Bioorg Med Chem Lett 23: 5448-51 (2013)
Article DOI: 10.1016/j.bmcl.2013.06.085 BindingDB Entry DOI: 10.7270/Q22R3T2S |
More data for this Ligand-Target Pair | |
Glucocorticoid receptor
(Homo sapiens (Human)) | BDBM50440109
(CHEMBL2426109)Show SMILES CC(CNC(=O)CC(F)(F)F)[C@@H](c1ccccc1)c1ccc2n(ncc2c1)-c1ccc(F)cc1 |r| Show InChI InChI=1S/C26H23F4N3O/c1-17(15-31-24(34)14-26(28,29)30)25(18-5-3-2-4-6-18)19-7-12-23-20(13-19)16-32-33(23)22-10-8-21(27)9-11-22/h2-13,16-17,25H,14-15H2,1H3,(H,31,34)/t17?,25-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 2.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
Curated by ChEMBL
| Assay Description Binding affinity to glucocorticoid receptor (unknown origin) by fluorescence assay |
Bioorg Med Chem Lett 23: 5448-51 (2013)
Article DOI: 10.1016/j.bmcl.2013.06.085 BindingDB Entry DOI: 10.7270/Q22R3T2S |
More data for this Ligand-Target Pair | |
Glucocorticoid receptor
(Homo sapiens (Human)) | BDBM50440106
(CHEMBL2426113)Show SMILES CC(C)C[C@@H](c1ccc2n(ncc2c1)-c1ccc(F)cc1)C(C)(C)CNC(=O)NC(C)(C)C |r| Show InChI InChI=1S/C27H37FN4O/c1-18(2)14-23(27(6,7)17-29-25(33)31-26(3,4)5)19-8-13-24-20(15-19)16-30-32(24)22-11-9-21(28)10-12-22/h8-13,15-16,18,23H,14,17H2,1-7H3,(H2,29,31,33)/t23-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 3.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
Curated by ChEMBL
| Assay Description Binding affinity to glucocorticoid receptor (unknown origin) by fluorescence assay |
Bioorg Med Chem Lett 23: 5448-51 (2013)
Article DOI: 10.1016/j.bmcl.2013.06.085 BindingDB Entry DOI: 10.7270/Q22R3T2S |
More data for this Ligand-Target Pair | |
Glucocorticoid receptor
(Homo sapiens (Human)) | BDBM50440098
(CHEMBL2426112)Show SMILES CC(C)(C)NC(=O)NCC(C)(C)[C@@H](c1ccccc1)c1ccc2n(ncc2c1)-c1ccc(F)cc1 |r| Show InChI InChI=1S/C29H33FN4O/c1-28(2,3)33-27(35)31-19-29(4,5)26(20-9-7-6-8-10-20)21-11-16-25-22(17-21)18-32-34(25)24-14-12-23(30)13-15-24/h6-18,26H,19H2,1-5H3,(H2,31,33,35)/t26-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 5.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
Curated by ChEMBL
| Assay Description Binding affinity to glucocorticoid receptor (unknown origin) by fluorescence assay |
Bioorg Med Chem Lett 23: 5448-51 (2013)
Article DOI: 10.1016/j.bmcl.2013.06.085 BindingDB Entry DOI: 10.7270/Q22R3T2S |
More data for this Ligand-Target Pair | |
Glucocorticoid receptor
(Homo sapiens (Human)) | BDBM50440108
(CHEMBL2426110)Show SMILES CC(C)(CNC(=O)NCC(F)(F)F)[C@@H](c1ccccc1)c1ccc2n(ncc2c1)-c1ccc(F)cc1 |r| Show InChI InChI=1S/C27H26F4N4O/c1-26(2,16-32-25(36)33-17-27(29,30)31)24(18-6-4-3-5-7-18)19-8-13-23-20(14-19)15-34-35(23)22-11-9-21(28)10-12-22/h3-15,24H,16-17H2,1-2H3,(H2,32,33,36)/t24-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
Curated by ChEMBL
| Assay Description Binding affinity to glucocorticoid receptor (unknown origin) by fluorescence assay |
Bioorg Med Chem Lett 23: 5448-51 (2013)
Article DOI: 10.1016/j.bmcl.2013.06.085 BindingDB Entry DOI: 10.7270/Q22R3T2S |
More data for this Ligand-Target Pair | |
Progesterone receptor
(Homo sapiens (Human)) | BDBM50440097
(CHEMBL2426118)Show SMILES CC(C)(CNS(=O)(=O)CC(F)(F)F)[C@@H](c1ccccc1)c1ccc2n(ncc2c1)-c1ccc(F)cc1 |r| Show InChI InChI=1S/C26H25F4N3O2S/c1-25(2,16-32-36(34,35)17-26(28,29)30)24(18-6-4-3-5-7-18)19-8-13-23-20(14-19)15-31-33(23)22-11-9-21(27)10-12-22/h3-15,24,32H,16-17H2,1-2H3/t24-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 406 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
Curated by ChEMBL
| Assay Description Binding affinity to progesterone receptor (unknown origin) by fluorescence assay |
Bioorg Med Chem Lett 23: 5448-51 (2013)
Article DOI: 10.1016/j.bmcl.2013.06.085 BindingDB Entry DOI: 10.7270/Q22R3T2S |
More data for this Ligand-Target Pair | |
Androgen receptor
(Homo sapiens (Human)) | BDBM50440096
(CHEMBL2426124)Show SMILES CC(C)(CNC(=O)CC(F)(F)F)[C@@H](c1ccccc1)c1ccc2n(ncc2c1)-c1ccc(F)cc1 |r| Show InChI InChI=1S/C27H25F4N3O/c1-26(2,17-32-24(35)15-27(29,30)31)25(18-6-4-3-5-7-18)19-8-13-23-20(14-19)16-33-34(23)22-11-9-21(28)10-12-22/h3-14,16,25H,15,17H2,1-2H3,(H,32,35)/t25-/m0/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
Curated by ChEMBL
| Assay Description Binding affinity to androgen receptor (unknown origin) by fluorescence assay |
Bioorg Med Chem Lett 23: 5448-51 (2013)
Article DOI: 10.1016/j.bmcl.2013.06.085 BindingDB Entry DOI: 10.7270/Q22R3T2S |
More data for this Ligand-Target Pair | |
Androgen receptor
(Homo sapiens (Human)) | BDBM50440097
(CHEMBL2426118)Show SMILES CC(C)(CNS(=O)(=O)CC(F)(F)F)[C@@H](c1ccccc1)c1ccc2n(ncc2c1)-c1ccc(F)cc1 |r| Show InChI InChI=1S/C26H25F4N3O2S/c1-25(2,16-32-36(34,35)17-26(28,29)30)24(18-6-4-3-5-7-18)19-8-13-23-20(14-19)15-31-33(23)22-11-9-21(27)10-12-22/h3-15,24,32H,16-17H2,1-2H3/t24-/m0/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
Curated by ChEMBL
| Assay Description Binding affinity to androgen receptor (unknown origin) by fluorescence assay |
Bioorg Med Chem Lett 23: 5448-51 (2013)
Article DOI: 10.1016/j.bmcl.2013.06.085 BindingDB Entry DOI: 10.7270/Q22R3T2S |
More data for this Ligand-Target Pair | |
Androgen receptor
(Homo sapiens (Human)) | BDBM50440098
(CHEMBL2426112)Show SMILES CC(C)(C)NC(=O)NCC(C)(C)[C@@H](c1ccccc1)c1ccc2n(ncc2c1)-c1ccc(F)cc1 |r| Show InChI InChI=1S/C29H33FN4O/c1-28(2,3)33-27(35)31-19-29(4,5)26(20-9-7-6-8-10-20)21-11-16-25-22(17-21)18-32-34(25)24-14-12-23(30)13-15-24/h6-18,26H,19H2,1-5H3,(H2,31,33,35)/t26-/m0/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
Curated by ChEMBL
| Assay Description Binding affinity to androgen receptor (unknown origin) by fluorescence assay |
Bioorg Med Chem Lett 23: 5448-51 (2013)
Article DOI: 10.1016/j.bmcl.2013.06.085 BindingDB Entry DOI: 10.7270/Q22R3T2S |
More data for this Ligand-Target Pair | |
Progesterone receptor
(Homo sapiens (Human)) | BDBM50440096
(CHEMBL2426124)Show SMILES CC(C)(CNC(=O)CC(F)(F)F)[C@@H](c1ccccc1)c1ccc2n(ncc2c1)-c1ccc(F)cc1 |r| Show InChI InChI=1S/C27H25F4N3O/c1-26(2,17-32-24(35)15-27(29,30)31)25(18-6-4-3-5-7-18)19-8-13-23-20(14-19)16-33-34(23)22-11-9-21(28)10-12-22/h3-14,16,25H,15,17H2,1-2H3,(H,32,35)/t25-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
Curated by ChEMBL
| Assay Description Binding affinity to progesterone receptor (unknown origin) by fluorescence assay |
Bioorg Med Chem Lett 23: 5448-51 (2013)
Article DOI: 10.1016/j.bmcl.2013.06.085 BindingDB Entry DOI: 10.7270/Q22R3T2S |
More data for this Ligand-Target Pair | |
Progesterone receptor
(Homo sapiens (Human)) | BDBM50440098
(CHEMBL2426112)Show SMILES CC(C)(C)NC(=O)NCC(C)(C)[C@@H](c1ccccc1)c1ccc2n(ncc2c1)-c1ccc(F)cc1 |r| Show InChI InChI=1S/C29H33FN4O/c1-28(2,3)33-27(35)31-19-29(4,5)26(20-9-7-6-8-10-20)21-11-16-25-22(17-21)18-32-34(25)24-14-12-23(30)13-15-24/h6-18,26H,19H2,1-5H3,(H2,31,33,35)/t26-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
Curated by ChEMBL
| Assay Description Binding affinity to progesterone receptor (unknown origin) by fluorescence assay |
Bioorg Med Chem Lett 23: 5448-51 (2013)
Article DOI: 10.1016/j.bmcl.2013.06.085 BindingDB Entry DOI: 10.7270/Q22R3T2S |
More data for this Ligand-Target Pair | |
Mineralocorticoid receptor
(Homo sapiens (Human)) | BDBM50440096
(CHEMBL2426124)Show SMILES CC(C)(CNC(=O)CC(F)(F)F)[C@@H](c1ccccc1)c1ccc2n(ncc2c1)-c1ccc(F)cc1 |r| Show InChI InChI=1S/C27H25F4N3O/c1-26(2,17-32-24(35)15-27(29,30)31)25(18-6-4-3-5-7-18)19-8-13-23-20(14-19)16-33-34(23)22-11-9-21(28)10-12-22/h3-14,16,25H,15,17H2,1-2H3,(H,32,35)/t25-/m0/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
Curated by ChEMBL
| Assay Description Agonist activity at mineralocorticoid receptor in human A549 cells by fluorescence assay |
Bioorg Med Chem Lett 23: 5448-51 (2013)
Article DOI: 10.1016/j.bmcl.2013.06.085 BindingDB Entry DOI: 10.7270/Q22R3T2S |
More data for this Ligand-Target Pair | |
Mineralocorticoid receptor
(Homo sapiens (Human)) | BDBM50440097
(CHEMBL2426118)Show SMILES CC(C)(CNS(=O)(=O)CC(F)(F)F)[C@@H](c1ccccc1)c1ccc2n(ncc2c1)-c1ccc(F)cc1 |r| Show InChI InChI=1S/C26H25F4N3O2S/c1-25(2,16-32-36(34,35)17-26(28,29)30)24(18-6-4-3-5-7-18)19-8-13-23-20(14-19)15-31-33(23)22-11-9-21(27)10-12-22/h3-15,24,32H,16-17H2,1-2H3/t24-/m0/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
Curated by ChEMBL
| Assay Description Agonist activity at mineralocorticoid receptor in human A549 cells by fluorescence assay |
Bioorg Med Chem Lett 23: 5448-51 (2013)
Article DOI: 10.1016/j.bmcl.2013.06.085 BindingDB Entry DOI: 10.7270/Q22R3T2S |
More data for this Ligand-Target Pair | |
Mineralocorticoid receptor
(Homo sapiens (Human)) | BDBM50440098
(CHEMBL2426112)Show SMILES CC(C)(C)NC(=O)NCC(C)(C)[C@@H](c1ccccc1)c1ccc2n(ncc2c1)-c1ccc(F)cc1 |r| Show InChI InChI=1S/C29H33FN4O/c1-28(2,3)33-27(35)31-19-29(4,5)26(20-9-7-6-8-10-20)21-11-16-25-22(17-21)18-32-34(25)24-14-12-23(30)13-15-24/h6-18,26H,19H2,1-5H3,(H2,31,33,35)/t26-/m0/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
Curated by ChEMBL
| Assay Description Agonist activity at mineralocorticoid receptor in human A549 cells by fluorescence assay |
Bioorg Med Chem Lett 23: 5448-51 (2013)
Article DOI: 10.1016/j.bmcl.2013.06.085 BindingDB Entry DOI: 10.7270/Q22R3T2S |
More data for this Ligand-Target Pair | |
Glucocorticoid receptor
(Homo sapiens (Human)) | BDBM50440099
(CHEMBL2426121)Show SMILES CCS(=O)(=O)NCC(C)[C@@H](c1ccccc1)c1ccc2n(ncc2c1)-c1ccc(F)cc1 |r| Show InChI InChI=1S/C25H26FN3O2S/c1-3-32(30,31)28-16-18(2)25(19-7-5-4-6-8-19)20-9-14-24-21(15-20)17-27-29(24)23-12-10-22(26)11-13-23/h4-15,17-18,25,28H,3,16H2,1-2H3/t18?,25-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 13 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
Curated by ChEMBL
| Assay Description Transactivation activity at glucocorticoid receptor ligand binding domain (unknown origin) expressed in human Hela cells co-expressing GAL4 DNA bindi... |
Bioorg Med Chem Lett 23: 5448-51 (2013)
Article DOI: 10.1016/j.bmcl.2013.06.085 BindingDB Entry DOI: 10.7270/Q22R3T2S |
More data for this Ligand-Target Pair | |
Glucocorticoid receptor
(Homo sapiens (Human)) | BDBM18207
((1R,2S,10S,11S,13R,14R,15S,17S)-1-fluoro-14,17-dih...)Show SMILES [H][C@@]12C[C@@H](C)[C@](O)(C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]1(F)[C@@]2([H])CCC2=CC(=O)C=C[C@]12C |c:28,t:24| Show InChI InChI=1S/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15+,16+,17+,19+,20+,21+,22+/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| DrugBank PDB Article PubMed
| n/a | n/a | n/a | n/a | 2.5 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
Curated by ChEMBL
| Assay Description Transrepression activity at glucocorticoid receptor in human A549 cells assessed as inhibition of PMA-stimulated AP1 response element by luciferase r... |
Bioorg Med Chem Lett 23: 5448-51 (2013)
Article DOI: 10.1016/j.bmcl.2013.06.085 BindingDB Entry DOI: 10.7270/Q22R3T2S |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Glucocorticoid receptor
(Homo sapiens (Human)) | BDBM50440101
(CHEMBL2426119)Show SMILES CC(CNS(=O)(=O)CC(F)(F)F)[C@@H](c1ccccc1)c1ccc2n(ncc2c1)-c1ccc(F)cc1 |r| Show InChI InChI=1S/C25H23F4N3O2S/c1-17(14-31-35(33,34)16-25(27,28)29)24(18-5-3-2-4-6-18)19-7-12-23-20(13-19)15-30-32(23)22-10-8-21(26)9-11-22/h2-13,15,17,24,31H,14,16H2,1H3/t17?,24-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 26 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
Curated by ChEMBL
| Assay Description Transactivation activity at glucocorticoid receptor ligand binding domain (unknown origin) expressed in human Hela cells co-expressing GAL4 DNA bindi... |
Bioorg Med Chem Lett 23: 5448-51 (2013)
Article DOI: 10.1016/j.bmcl.2013.06.085 BindingDB Entry DOI: 10.7270/Q22R3T2S |
More data for this Ligand-Target Pair | |
Glucocorticoid receptor
(Homo sapiens (Human)) | BDBM50440097
(CHEMBL2426118)Show SMILES CC(C)(CNS(=O)(=O)CC(F)(F)F)[C@@H](c1ccccc1)c1ccc2n(ncc2c1)-c1ccc(F)cc1 |r| Show InChI InChI=1S/C26H25F4N3O2S/c1-25(2,16-32-36(34,35)17-26(28,29)30)24(18-6-4-3-5-7-18)19-8-13-23-20(14-19)15-31-33(23)22-11-9-21(27)10-12-22/h3-15,24,32H,16-17H2,1-2H3/t24-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 202 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
Curated by ChEMBL
| Assay Description Transactivation activity at glucocorticoid receptor ligand binding domain (unknown origin) expressed in human Hela cells co-expressing GAL4 DNA bindi... |
Bioorg Med Chem Lett 23: 5448-51 (2013)
Article DOI: 10.1016/j.bmcl.2013.06.085 BindingDB Entry DOI: 10.7270/Q22R3T2S |
More data for this Ligand-Target Pair | |
Glucocorticoid receptor
(Homo sapiens (Human)) | BDBM50440102
(CHEMBL2426117)Show SMILES CC(C)(CNS(=O)(=O)C1CC1)[C@@H](c1ccccc1)c1ccc2n(ncc2c1)-c1ccc(F)cc1 |r| Show InChI InChI=1S/C27H28FN3O2S/c1-27(2,18-30-34(32,33)24-13-14-24)26(19-6-4-3-5-7-19)20-8-15-25-21(16-20)17-29-31(25)23-11-9-22(28)10-12-23/h3-12,15-17,24,26,30H,13-14,18H2,1-2H3/t26-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 261 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
Curated by ChEMBL
| Assay Description Transactivation activity at glucocorticoid receptor ligand binding domain (unknown origin) expressed in human Hela cells co-expressing GAL4 DNA bindi... |
Bioorg Med Chem Lett 23: 5448-51 (2013)
Article DOI: 10.1016/j.bmcl.2013.06.085 BindingDB Entry DOI: 10.7270/Q22R3T2S |
More data for this Ligand-Target Pair | |
Glucocorticoid receptor
(Homo sapiens (Human)) | BDBM50440103
(CHEMBL2426116)Show SMILES CCCS(=O)(=O)NCC(C)(C)[C@@H](c1ccccc1)c1ccc2n(ncc2c1)-c1ccc(F)cc1 |r| Show InChI InChI=1S/C27H30FN3O2S/c1-4-16-34(32,33)30-19-27(2,3)26(20-8-6-5-7-9-20)21-10-15-25-22(17-21)18-29-31(25)24-13-11-23(28)12-14-24/h5-15,17-18,26,30H,4,16,19H2,1-3H3/t26-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
Curated by ChEMBL
| Assay Description Transactivation activity at glucocorticoid receptor ligand binding domain (unknown origin) expressed in human Hela cells co-expressing GAL4 DNA bindi... |
Bioorg Med Chem Lett 23: 5448-51 (2013)
Article DOI: 10.1016/j.bmcl.2013.06.085 BindingDB Entry DOI: 10.7270/Q22R3T2S |
More data for this Ligand-Target Pair | |
Glucocorticoid receptor
(Homo sapiens (Human)) | BDBM50440104
(CHEMBL2426115)Show SMILES CCS(=O)(=O)NCC(C)(C)[C@@H](c1ccccc1)c1ccc2n(ncc2c1)-c1ccc(F)cc1 |r| Show InChI InChI=1S/C26H28FN3O2S/c1-4-33(31,32)29-18-26(2,3)25(19-8-6-5-7-9-19)20-10-15-24-21(16-20)17-28-30(24)23-13-11-22(27)12-14-23/h5-17,25,29H,4,18H2,1-3H3/t25-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 214 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
Curated by ChEMBL
| Assay Description Transactivation activity at glucocorticoid receptor ligand binding domain (unknown origin) expressed in human Hela cells co-expressing GAL4 DNA bindi... |
Bioorg Med Chem Lett 23: 5448-51 (2013)
Article DOI: 10.1016/j.bmcl.2013.06.085 BindingDB Entry DOI: 10.7270/Q22R3T2S |
More data for this Ligand-Target Pair | |
Glucocorticoid receptor
(Homo sapiens (Human)) | BDBM50440105
(CHEMBL2426114)Show SMILES CC(C)(CNS(C)(=O)=O)[C@@H](c1ccccc1)c1ccc2n(ncc2c1)-c1ccc(F)cc1 |r| Show InChI InChI=1S/C25H26FN3O2S/c1-25(2,17-28-32(3,30)31)24(18-7-5-4-6-8-18)19-9-14-23-20(15-19)16-27-29(23)22-12-10-21(26)11-13-22/h4-16,24,28H,17H2,1-3H3/t24-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 148 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
Curated by ChEMBL
| Assay Description Transactivation activity at glucocorticoid receptor ligand binding domain (unknown origin) expressed in human Hela cells co-expressing GAL4 DNA bindi... |
Bioorg Med Chem Lett 23: 5448-51 (2013)
Article DOI: 10.1016/j.bmcl.2013.06.085 BindingDB Entry DOI: 10.7270/Q22R3T2S |
More data for this Ligand-Target Pair | |
Glucocorticoid receptor
(Homo sapiens (Human)) | BDBM50440106
(CHEMBL2426113)Show SMILES CC(C)C[C@@H](c1ccc2n(ncc2c1)-c1ccc(F)cc1)C(C)(C)CNC(=O)NC(C)(C)C |r| Show InChI InChI=1S/C27H37FN4O/c1-18(2)14-23(27(6,7)17-29-25(33)31-26(3,4)5)19-8-13-24-20(15-19)16-30-32(24)22-11-9-21(28)10-12-22/h8-13,15-16,18,23H,14,17H2,1-7H3,(H2,29,31,33)/t23-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 126 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
Curated by ChEMBL
| Assay Description Transactivation activity at glucocorticoid receptor ligand binding domain (unknown origin) expressed in human Hela cells co-expressing GAL4 DNA bindi... |
Bioorg Med Chem Lett 23: 5448-51 (2013)
Article DOI: 10.1016/j.bmcl.2013.06.085 BindingDB Entry DOI: 10.7270/Q22R3T2S |
More data for this Ligand-Target Pair | |
Glucocorticoid receptor
(Homo sapiens (Human)) | BDBM50440098
(CHEMBL2426112)Show SMILES CC(C)(C)NC(=O)NCC(C)(C)[C@@H](c1ccccc1)c1ccc2n(ncc2c1)-c1ccc(F)cc1 |r| Show InChI InChI=1S/C29H33FN4O/c1-28(2,3)33-27(35)31-19-29(4,5)26(20-9-7-6-8-10-20)21-11-16-25-22(17-21)18-32-34(25)24-14-12-23(30)13-15-24/h6-18,26H,19H2,1-5H3,(H2,31,33,35)/t26-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 429 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
Curated by ChEMBL
| Assay Description Transactivation activity at glucocorticoid receptor ligand binding domain (unknown origin) expressed in human Hela cells co-expressing GAL4 DNA bindi... |
Bioorg Med Chem Lett 23: 5448-51 (2013)
Article DOI: 10.1016/j.bmcl.2013.06.085 BindingDB Entry DOI: 10.7270/Q22R3T2S |
More data for this Ligand-Target Pair | |
Glucocorticoid receptor
(Homo sapiens (Human)) | BDBM50440107
(CHEMBL2426111)Show SMILES CC(C)C[C@@H](c1ccc2n(ncc2c1)-c1ccc(F)cc1)C(C)(C)CNC(=O)NCC(F)(F)F |r| Show InChI InChI=1S/C25H30F4N4O/c1-16(2)11-21(24(3,4)14-30-23(34)31-15-25(27,28)29)17-5-10-22-18(12-17)13-32-33(22)20-8-6-19(26)7-9-20/h5-10,12-13,16,21H,11,14-15H2,1-4H3,(H2,30,31,34)/t21-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 501 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
Curated by ChEMBL
| Assay Description Transactivation activity at glucocorticoid receptor ligand binding domain (unknown origin) expressed in human Hela cells co-expressing GAL4 DNA bindi... |
Bioorg Med Chem Lett 23: 5448-51 (2013)
Article DOI: 10.1016/j.bmcl.2013.06.085 BindingDB Entry DOI: 10.7270/Q22R3T2S |
More data for this Ligand-Target Pair | |
Glucocorticoid receptor
(Homo sapiens (Human)) | BDBM50440108
(CHEMBL2426110)Show SMILES CC(C)(CNC(=O)NCC(F)(F)F)[C@@H](c1ccccc1)c1ccc2n(ncc2c1)-c1ccc(F)cc1 |r| Show InChI InChI=1S/C27H26F4N4O/c1-26(2,16-32-25(36)33-17-27(29,30)31)24(18-6-4-3-5-7-18)19-8-13-23-20(14-19)15-34-35(23)22-11-9-21(28)10-12-22/h3-15,24H,16-17H2,1-2H3,(H2,32,33,36)/t24-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
Curated by ChEMBL
| Assay Description Transactivation activity at glucocorticoid receptor ligand binding domain (unknown origin) expressed in human Hela cells co-expressing GAL4 DNA bindi... |
Bioorg Med Chem Lett 23: 5448-51 (2013)
Article DOI: 10.1016/j.bmcl.2013.06.085 BindingDB Entry DOI: 10.7270/Q22R3T2S |
More data for this Ligand-Target Pair | |
Glucocorticoid receptor
(Homo sapiens (Human)) | BDBM50440109
(CHEMBL2426109)Show SMILES CC(CNC(=O)CC(F)(F)F)[C@@H](c1ccccc1)c1ccc2n(ncc2c1)-c1ccc(F)cc1 |r| Show InChI InChI=1S/C26H23F4N3O/c1-17(15-31-24(34)14-26(28,29)30)25(18-5-3-2-4-6-18)19-7-12-23-20(13-19)16-32-33(23)22-10-8-21(27)9-11-22/h2-13,16-17,25H,14-15H2,1H3,(H,31,34)/t17?,25-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 21 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
Curated by ChEMBL
| Assay Description Transactivation activity at glucocorticoid receptor ligand binding domain (unknown origin) expressed in human Hela cells co-expressing GAL4 DNA bindi... |
Bioorg Med Chem Lett 23: 5448-51 (2013)
Article DOI: 10.1016/j.bmcl.2013.06.085 BindingDB Entry DOI: 10.7270/Q22R3T2S |
More data for this Ligand-Target Pair | |
Glucocorticoid receptor
(Homo sapiens (Human)) | BDBM50440109
(CHEMBL2426109)Show SMILES CC(CNC(=O)CC(F)(F)F)[C@@H](c1ccccc1)c1ccc2n(ncc2c1)-c1ccc(F)cc1 |r| Show InChI InChI=1S/C26H23F4N3O/c1-17(15-31-24(34)14-26(28,29)30)25(18-5-3-2-4-6-18)19-7-12-23-20(13-19)16-32-33(23)22-10-8-21(27)9-11-22/h2-13,16-17,25H,14-15H2,1H3,(H,31,34)/t17?,25-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 20.7 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
Curated by ChEMBL
| Assay Description Transactivation activity at glucocorticoid receptor ligand binding domain (unknown origin) expressed in human Hela cells co-expressing GAL4 DNA bindi... |
Bioorg Med Chem Lett 23: 5448-51 (2013)
Article DOI: 10.1016/j.bmcl.2013.06.085 BindingDB Entry DOI: 10.7270/Q22R3T2S |
More data for this Ligand-Target Pair | |
Glucocorticoid receptor
(Homo sapiens (Human)) | BDBM50440110
(CHEMBL2426128)Show SMILES CC(C)C[C@@H](c1ccc2n(ncc2c1)-c1ccc(F)cc1)C(C)(C)CNC(=O)CC(F)(F)F |r| Show InChI InChI=1S/C25H29F4N3O/c1-16(2)11-21(24(3,4)15-30-23(33)13-25(27,28)29)17-5-10-22-18(12-17)14-31-32(22)20-8-6-19(26)7-9-20/h5-10,12,14,16,21H,11,13,15H2,1-4H3,(H,30,33)/t21-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 262 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
Curated by ChEMBL
| Assay Description Transactivation activity at glucocorticoid receptor ligand binding domain (unknown origin) expressed in human Hela cells co-expressing GAL4 DNA bindi... |
Bioorg Med Chem Lett 23: 5448-51 (2013)
Article DOI: 10.1016/j.bmcl.2013.06.085 BindingDB Entry DOI: 10.7270/Q22R3T2S |
More data for this Ligand-Target Pair | |
Glucocorticoid receptor
(Homo sapiens (Human)) | BDBM50440111
(CHEMBL2426127)Show SMILES CC(C)(CNC(=O)Cc1ccccc1)[C@@H](c1ccccc1)c1ccc2n(ncc2c1)-c1ccc(F)cc1 |r| Show InChI InChI=1S/C32H30FN3O/c1-32(2,22-34-30(37)19-23-9-5-3-6-10-23)31(24-11-7-4-8-12-24)25-13-18-29-26(20-25)21-35-36(29)28-16-14-27(33)15-17-28/h3-18,20-21,31H,19,22H2,1-2H3,(H,34,37)/t31-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 977 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
Curated by ChEMBL
| Assay Description Transactivation activity at glucocorticoid receptor ligand binding domain (unknown origin) expressed in human Hela cells co-expressing GAL4 DNA bindi... |
Bioorg Med Chem Lett 23: 5448-51 (2013)
Article DOI: 10.1016/j.bmcl.2013.06.085 BindingDB Entry DOI: 10.7270/Q22R3T2S |
More data for this Ligand-Target Pair | |
Glucocorticoid receptor
(Homo sapiens (Human)) | BDBM50440112
(CHEMBL2426126)Show SMILES CC(C)(C)CC(=O)NCC(C)(C)[C@@H](c1ccccc1)c1ccc2n(ncc2c1)-c1ccc(F)cc1 |r| Show InChI InChI=1S/C30H34FN3O/c1-29(2,3)18-27(35)32-20-30(4,5)28(21-9-7-6-8-10-21)22-11-16-26-23(17-22)19-33-34(26)25-14-12-24(31)13-15-25/h6-17,19,28H,18,20H2,1-5H3,(H,32,35)/t28-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
Curated by ChEMBL
| Assay Description Transactivation activity at glucocorticoid receptor ligand binding domain (unknown origin) expressed in human Hela cells co-expressing GAL4 DNA bindi... |
Bioorg Med Chem Lett 23: 5448-51 (2013)
Article DOI: 10.1016/j.bmcl.2013.06.085 BindingDB Entry DOI: 10.7270/Q22R3T2S |
More data for this Ligand-Target Pair | |
Glucocorticoid receptor
(Homo sapiens (Human)) | BDBM50440113
(CHEMBL2426125)Show SMILES CC(C)(C)C(=O)NCC(C)(C)[C@@H](c1ccccc1)c1ccc2n(ncc2c1)-c1ccc(F)cc1 |r| Show InChI InChI=1S/C29H32FN3O/c1-28(2,3)27(34)31-19-29(4,5)26(20-9-7-6-8-10-20)21-11-16-25-22(17-21)18-32-33(25)24-14-12-23(30)13-15-24/h6-18,26H,19H2,1-5H3,(H,31,34)/t26-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 394 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
Curated by ChEMBL
| Assay Description Transactivation activity at glucocorticoid receptor ligand binding domain (unknown origin) expressed in human Hela cells co-expressing GAL4 DNA bindi... |
Bioorg Med Chem Lett 23: 5448-51 (2013)
Article DOI: 10.1016/j.bmcl.2013.06.085 BindingDB Entry DOI: 10.7270/Q22R3T2S |
More data for this Ligand-Target Pair | |
Glucocorticoid receptor
(Homo sapiens (Human)) | BDBM50440096
(CHEMBL2426124)Show SMILES CC(C)(CNC(=O)CC(F)(F)F)[C@@H](c1ccccc1)c1ccc2n(ncc2c1)-c1ccc(F)cc1 |r| Show InChI InChI=1S/C27H25F4N3O/c1-26(2,17-32-24(35)15-27(29,30)31)25(18-6-4-3-5-7-18)19-8-13-23-20(14-19)16-33-34(23)22-11-9-21(28)10-12-22/h3-14,16,25H,15,17H2,1-2H3,(H,32,35)/t25-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 129 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
Curated by ChEMBL
| Assay Description Transactivation activity at glucocorticoid receptor ligand binding domain (unknown origin) expressed in human Hela cells co-expressing GAL4 DNA bindi... |
Bioorg Med Chem Lett 23: 5448-51 (2013)
Article DOI: 10.1016/j.bmcl.2013.06.085 BindingDB Entry DOI: 10.7270/Q22R3T2S |
More data for this Ligand-Target Pair | |
Glucocorticoid receptor
(Homo sapiens (Human)) | BDBM50440114
(CHEMBL2426123)Show SMILES CC(C)(CNC(=O)C(F)(F)F)[C@@H](c1ccccc1)c1ccc2n(ncc2c1)-c1ccc(F)cc1 |r| Show InChI InChI=1S/C26H23F4N3O/c1-25(2,16-31-24(34)26(28,29)30)23(17-6-4-3-5-7-17)18-8-13-22-19(14-18)15-32-33(22)21-11-9-20(27)10-12-21/h3-15,23H,16H2,1-2H3,(H,31,34)/t23-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
Curated by ChEMBL
| Assay Description Transactivation activity at glucocorticoid receptor ligand binding domain (unknown origin) expressed in human Hela cells co-expressing GAL4 DNA bindi... |
Bioorg Med Chem Lett 23: 5448-51 (2013)
Article DOI: 10.1016/j.bmcl.2013.06.085 BindingDB Entry DOI: 10.7270/Q22R3T2S |
More data for this Ligand-Target Pair | |