Compile Data Set for Download or QSAR

Found 27 hits Enz. Inhib. hit(s) with all data for assayid = 1 entry = 1843   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Isoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D] (Homo sapiens (Human))	BDBM343674 (6-Chloro-3-(4-methoxy-1-benzofuran-2-yl)imidazo[1,...) Show SMILES C(Oc1ccc2ncc(-c3cc4ccccc4o3)n2n1)C1CNCCO1 Show InChI InChI=1S/C19H18N4O3/c1-2-4-16-13(3-1)9-17(26-16)15-11-21-18-5-6-19(22-23(15)18)25-12-14-10-20-7-8-24-14/h1-6,9,11,14,20H,7-8,10,12H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent					Assay Description For the assay 50 nL of a 100fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384well microtiter plate (Gr...				US Patent US9777004 (2017) BindingDB Entry DOI: 10.7270/Q2B27XDM
					More data for this Ligand-Target Pair
Isoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D] (Homo sapiens (Human))	BDBM343675 (6-Chloro-3-(5-methoxy-1-benzofuran-2-yl)imidazo[1,...) Show SMILES CC(C)(C)CNCCCOc1ccc2ncc(-c3cc4ccccc4o3)n2n1 Show InChI InChI=1S/C22H26N4O2/c1-22(2,3)15-23-11-6-12-27-21-10-9-20-24-14-17(26(20)25-21)19-13-16-7-4-5-8-18(16)28-19/h4-5,7-10,13-14,23H,6,11-12,15H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent					Assay Description For the assay 50 nL of a 100fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384well microtiter plate (Gr...				US Patent US9777004 (2017) BindingDB Entry DOI: 10.7270/Q2B27XDM
					More data for this Ligand-Target Pair
Isoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D] (Homo sapiens (Human))	BDBM343673 (3-(1-Benzofuran-2-yl)-6-[2-(morpholin-2-yl)ethoxy]...) Show SMILES C(CC1CNCCO1)Oc1ccc2ncc(-c3cc4ccccc4o3)n2n1 Show InChI InChI=1S/C20H20N4O3/c1-2-4-17-14(3-1)11-18(27-17)16-13-22-19-5-6-20(23-24(16)19)26-9-7-15-12-21-8-10-25-15/h1-6,11,13,15,21H,7-10,12H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent					Assay Description For the assay 50 nL of a 100fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384well microtiter plate (Gr...				US Patent US9777004 (2017) BindingDB Entry DOI: 10.7270/Q2B27XDM
					More data for this Ligand-Target Pair
Isoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D] (Homo sapiens (Human))	BDBM343677 (3-(1-Benzofuran-2-yl)-6-{2-[(3R)-morpholin-3-yl]et...) Show SMILES C(C[C@@H]1COCCN1)Oc1ccc2ncc(-c3cc4ccccc4o3)n2n1 |r| Show InChI InChI=1S/C20H20N4O3/c1-2-4-17-14(3-1)11-18(27-17)16-12-22-19-5-6-20(23-24(16)19)26-9-7-15-13-25-10-8-21-15/h1-6,11-12,15,21H,7-10,13H2/t15-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent					Assay Description For the assay 50 nL of a 100fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384well microtiter plate (Gr...				US Patent US9777004 (2017) BindingDB Entry DOI: 10.7270/Q2B27XDM
					More data for this Ligand-Target Pair
Isoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D] (Homo sapiens (Human))	BDBM343676 (2-{[3-(1-Benzofuran-2-yl)imidazo[1,2-b]pyridazin-6...) Show SMILES C(COc1ccc2ncc(-c3cc4ccccc4o3)n2n1)NCC1CC1 Show InChI InChI=1S/C20H20N4O2/c1-2-4-17-15(3-1)11-18(26-17)16-13-22-19-7-8-20(23-24(16)19)25-10-9-21-12-14-5-6-14/h1-4,7-8,11,13-14,21H,5-6,9-10,12H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent					Assay Description For the assay 50 nL of a 100fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384well microtiter plate (Gr...				US Patent US9777004 (2017) BindingDB Entry DOI: 10.7270/Q2B27XDM
					More data for this Ligand-Target Pair
Isoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D] (Homo sapiens (Human))	BDBM343678 (3-{[3-(1-Benzofuran-2-yl)imidazo[1,2-b]pyridazin-6...) Show SMILES CC(C)NCCCOc1ccc2ncc(-c3cc4ccccc4o3)n2n1 Show InChI InChI=1S/C20H22N4O2/c1-14(2)21-10-5-11-25-20-9-8-19-22-13-16(24(19)23-20)18-12-15-6-3-4-7-17(15)26-18/h3-4,6-9,12-14,21H,5,10-11H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent					Assay Description For the assay 50 nL of a 100fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384well microtiter plate (Gr...				US Patent US9777004 (2017) BindingDB Entry DOI: 10.7270/Q2B27XDM
					More data for this Ligand-Target Pair
Isoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D] (Homo sapiens (Human))	BDBM343685 (N-(2-{[3-(1-Benzofuran-2-yl)imidazo[1,2-b]pyridazi...) Show SMILES C(COc1ccc2ncc(-c3cc4ccccc4o3)n2n1)NC1CC1 Show InChI InChI=1S/C19H18N4O2/c1-2-4-16-13(3-1)11-17(25-16)15-12-21-18-7-8-19(22-23(15)18)24-10-9-20-14-5-6-14/h1-4,7-8,11-12,14,20H,5-6,9-10H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent					Assay Description For the assay 50 nL of a 100fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384well microtiter plate (Gr...				US Patent US9777004 (2017) BindingDB Entry DOI: 10.7270/Q2B27XDM
					More data for this Ligand-Target Pair
Isoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D] (Homo sapiens (Human))	BDBM343679 (N-(2-{[3-(1-Benzofuran-2-yl)imidazo[1,2-b]pyridazi...) Show SMILES CC(C)NCCOc1ccc2ncc(-c3cc4ccccc4o3)n2n1 Show InChI InChI=1S/C19H20N4O2/c1-13(2)20-9-10-24-19-8-7-18-21-12-15(23(18)22-19)17-11-14-5-3-4-6-16(14)25-17/h3-8,11-13,20H,9-10H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent					Assay Description For the assay 50 nL of a 100fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384well microtiter plate (Gr...				US Patent US9777004 (2017) BindingDB Entry DOI: 10.7270/Q2B27XDM
					More data for this Ligand-Target Pair
Isoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D] (Homo sapiens (Human))	BDBM343682 (3-(1-Benzofuran-2-yl)-6-{2-[(3S)-morpholin-3-yl]et...) Show SMILES C(C[C@H]1COCCN1)Oc1ccc2ncc(-c3cc4ccccc4o3)n2n1 |r| Show InChI InChI=1S/C20H20N4O3/c1-2-4-17-14(3-1)11-18(27-17)16-12-22-19-5-6-20(23-24(16)19)26-9-7-15-13-25-10-8-21-15/h1-6,11-12,15,21H,7-10,13H2/t15-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent					Assay Description For the assay 50 nL of a 100fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384well microtiter plate (Gr...				US Patent US9777004 (2017) BindingDB Entry DOI: 10.7270/Q2B27XDM
					More data for this Ligand-Target Pair
Isoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D] (Homo sapiens (Human))	BDBM343698 (3-(4-Fluoro-1-benzofuran-2-yl)-6-[(2R)-morpholin-2...) Show SMILES Fc1cccc2oc(cc12)-c1cnc2ccc(OC[C@H]3CNCCO3)nn12 |r| Show InChI InChI=1S/C19H17FN4O3/c20-14-2-1-3-16-13(14)8-17(27-16)15-10-22-18-4-5-19(23-24(15)18)26-11-12-9-21-6-7-25-12/h1-5,8,10,12,21H,6-7,9,11H2/t12-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent					Assay Description For the assay 50 nL of a 100fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384well microtiter plate (Gr...				US Patent US9777004 (2017) BindingDB Entry DOI: 10.7270/Q2B27XDM
					More data for this Ligand-Target Pair
Isoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D] (Homo sapiens (Human))	BDBM343699 (3-(5-Fluoro-1-benzofuran-2-yl)-6-[(2R)-morpholin-2...) Show SMILES Fc1ccc2oc(cc2c1)-c1cnc2ccc(OC[C@H]3CNCCO3)nn12 |r| Show InChI InChI=1S/C19H17FN4O3/c20-13-1-2-16-12(7-13)8-17(27-16)15-10-22-18-3-4-19(23-24(15)18)26-11-14-9-21-5-6-25-14/h1-4,7-8,10,14,21H,5-6,9,11H2/t14-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent					Assay Description For the assay 50 nL of a 100fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384well microtiter plate (Gr...				US Patent US9777004 (2017) BindingDB Entry DOI: 10.7270/Q2B27XDM
					More data for this Ligand-Target Pair
Isoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D] (Homo sapiens (Human))	BDBM343681 (N-(2-{[3-(1-Benzofuran-2-yl)imidazo[1,2-b]pyridazi...) Show SMILES CC(C)(C)CNCCOc1ccc2ncc(-c3cc4ccccc4o3)n2n1 Show InChI InChI=1S/C21H24N4O2/c1-21(2,3)14-22-10-11-26-20-9-8-19-23-13-16(25(19)24-20)18-12-15-6-4-5-7-17(15)27-18/h4-9,12-13,22H,10-11,14H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent					Assay Description For the assay 50 nL of a 100fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384well microtiter plate (Gr...				US Patent US9777004 (2017) BindingDB Entry DOI: 10.7270/Q2B27XDM
					More data for this Ligand-Target Pair
Isoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D] (Homo sapiens (Human))	BDBM343680 (3-(1-Benzofuran-2-yl)-6-[(2S)-morpholin-2-ylmethox...) Show SMILES C(Oc1ccc2ncc(-c3cc4ccccc4o3)n2n1)[C@@H]1CNCCO1 |r| Show InChI InChI=1S/C19H18N4O3/c1-2-4-16-13(3-1)9-17(26-16)15-11-21-18-5-6-19(22-23(15)18)25-12-14-10-20-7-8-24-14/h1-6,9,11,14,20H,7-8,10,12H2/t14-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent					Assay Description For the assay 50 nL of a 100fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384well microtiter plate (Gr...				US Patent US9777004 (2017) BindingDB Entry DOI: 10.7270/Q2B27XDM
					More data for this Ligand-Target Pair
Isoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D] (Homo sapiens (Human))	BDBM343683 (3-(1-Benzofuran-2-yl)-6-{2-[(2S)-pyrrolidin-2-yl]e...) Show SMILES C(C[C@@H]1CCCN1)Oc1ccc2ncc(-c3cc4ccccc4o3)n2n1 |r| Show InChI InChI=1S/C20H20N4O2/c1-2-6-17-14(4-1)12-18(26-17)16-13-22-19-7-8-20(23-24(16)19)25-11-9-15-5-3-10-21-15/h1-2,4,6-8,12-13,15,21H,3,5,9-11H2/t15-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent					Assay Description For the assay 50 nL of a 100fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384well microtiter plate (Gr...				US Patent US9777004 (2017) BindingDB Entry DOI: 10.7270/Q2B27XDM
					More data for this Ligand-Target Pair
Isoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D] (Homo sapiens (Human))	BDBM343688 (3-(1-Benzofuran-2-yl)-6-[(2R)-pyrrolidin-2-ylmetho...) Show SMILES C(Oc1ccc2ncc(-c3cc4ccccc4o3)n2n1)C1CCCN1 Show InChI InChI=1S/C19H18N4O2/c1-2-6-16-13(4-1)10-17(25-16)15-11-21-18-7-8-19(22-23(15)18)24-12-14-5-3-9-20-14/h1-2,4,6-8,10-11,14,20H,3,5,9,12H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent					Assay Description For the assay 50 nL of a 100fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384well microtiter plate (Gr...				US Patent US9777004 (2017) BindingDB Entry DOI: 10.7270/Q2B27XDM
					More data for this Ligand-Target Pair
Isoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D] (Homo sapiens (Human))	BDBM343687 (2-{[3-(1-Benzofuran-2-yl)imidazo[1,2-b]pyridazin-6...) Show SMILES CC(C)NCC(C)Oc1ccc2ncc(-c3cc4ccccc4o3)n2n1 |w:5.5| Show InChI InChI=1S/C20H22N4O2/c1-13(2)21-11-14(3)25-20-9-8-19-22-12-16(24(19)23-20)18-10-15-6-4-5-7-17(15)26-18/h4-10,12-14,21H,11H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent					Assay Description For the assay 50 nL of a 100fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384well microtiter plate (Gr...				US Patent US9777004 (2017) BindingDB Entry DOI: 10.7270/Q2B27XDM
					More data for this Ligand-Target Pair
Isoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D] (Homo sapiens (Human))	BDBM343684 (3-(1-Benzofuran-2-yl)-6-(piperidin-2-ylmethoxy)imi...) Show SMILES C(Oc1ccc2ncc(-c3cc4ccccc4o3)n2n1)C1CCCCN1 |w:20.23| Show InChI InChI=1S/C20H20N4O2/c1-2-7-17-14(5-1)11-18(26-17)16-12-22-19-8-9-20(23-24(16)19)25-13-15-6-3-4-10-21-15/h1-2,5,7-9,11-12,15,21H,3-4,6,10,13H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent					Assay Description For the assay 50 nL of a 100fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384well microtiter plate (Gr...				US Patent US9777004 (2017) BindingDB Entry DOI: 10.7270/Q2B27XDM
					More data for this Ligand-Target Pair
Isoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D] (Homo sapiens (Human))	BDBM343696 (3-(1-Benzofuran-2-yl)-6-[(3R)-pyrrolidin-3-yloxy]i...) Show SMILES C1C[C@H](CN1)Oc1ccc2ncc(-c3cc4ccccc4o3)n2n1 |r| Show InChI InChI=1S/C18H16N4O2/c1-2-4-15-12(3-1)9-16(24-15)14-11-20-17-5-6-18(21-22(14)17)23-13-7-8-19-10-13/h1-6,9,11,13,19H,7-8,10H2/t13-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent					Assay Description For the assay 50 nL of a 100fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384well microtiter plate (Gr...				US Patent US9777004 (2017) BindingDB Entry DOI: 10.7270/Q2B27XDM
					More data for this Ligand-Target Pair
Isoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D] (Homo sapiens (Human))	BDBM343686 (N-(2-{[3-(1-Benzofuran-2-yl)imidazo[1,2-b]pyridazi...) Show SMILES CC(C)(C)NCCOc1ccc2ncc(-c3cc4ccccc4o3)n2n1 Show InChI InChI=1S/C20H22N4O2/c1-20(2,3)22-10-11-25-19-9-8-18-21-13-15(24(18)23-19)17-12-14-6-4-5-7-16(14)26-17/h4-9,12-13,22H,10-11H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent					Assay Description For the assay 50 nL of a 100fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384well microtiter plate (Gr...				US Patent US9777004 (2017) BindingDB Entry DOI: 10.7270/Q2B27XDM
					More data for this Ligand-Target Pair
Isoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D] (Homo sapiens (Human))	BDBM343689 (3-(1-Benzofuran-2-yl)-6-(piperidin-3-yloxy)imidazo...) Show SMILES C1CNCC(C1)Oc1ccc2ncc(-c3cc4ccccc4o3)n2n1 |w:6.6| Show InChI InChI=1S/C19H18N4O2/c1-2-6-16-13(4-1)10-17(25-16)15-12-21-18-7-8-19(22-23(15)18)24-14-5-3-9-20-11-14/h1-2,4,6-8,10,12,14,20H,3,5,9,11H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent					Assay Description For the assay 50 nL of a 100fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384well microtiter plate (Gr...				US Patent US9777004 (2017) BindingDB Entry DOI: 10.7270/Q2B27XDM
					More data for this Ligand-Target Pair
Isoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D] (Homo sapiens (Human))	BDBM343688 (3-(1-Benzofuran-2-yl)-6-[(2R)-pyrrolidin-2-ylmetho...) Show SMILES C(Oc1ccc2ncc(-c3cc4ccccc4o3)n2n1)C1CCCN1 Show InChI InChI=1S/C19H18N4O2/c1-2-6-16-13(4-1)10-17(25-16)15-11-21-18-7-8-19(22-23(15)18)24-12-14-5-3-9-20-14/h1-2,4,6-8,10-11,14,20H,3,5,9,12H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent					Assay Description For the assay 50 nL of a 100fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384well microtiter plate (Gr...				US Patent US9777004 (2017) BindingDB Entry DOI: 10.7270/Q2B27XDM
					More data for this Ligand-Target Pair
Isoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D] (Homo sapiens (Human))	BDBM343697 (3-(1-Benzofuran-2-yl)-6-[(3R)-piperidin-3-yloxy]im...) Show SMILES C1CNC[C@@H](C1)Oc1ccc2ncc(-c3cc4ccccc4o3)n2n1 |r| Show InChI InChI=1S/C19H18N4O2/c1-2-6-16-13(4-1)10-17(25-16)15-12-21-18-7-8-19(22-23(15)18)24-14-5-3-9-20-11-14/h1-2,4,6-8,10,12,14,20H,3,5,9,11H2/t14-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent					Assay Description For the assay 50 nL of a 100fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384well microtiter plate (Gr...				US Patent US9777004 (2017) BindingDB Entry DOI: 10.7270/Q2B27XDM
					More data for this Ligand-Target Pair
Isoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D] (Homo sapiens (Human))	BDBM343692 (Formic acid-N-(2-{[3-(1-benzofuran-2-yl)imidazo[1,...) Show SMILES CC(C)NCC(Oc1ccc2ncc(-c3cc4ccccc4o3)n2n1)c1ccccc1 |w:6.5| Show InChI InChI=1S/C25H24N4O2/c1-17(2)26-16-23(18-8-4-3-5-9-18)31-25-13-12-24-27-15-20(29(24)28-25)22-14-19-10-6-7-11-21(19)30-22/h3-15,17,23,26H,16H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent					Assay Description For the assay 50 nL of a 100fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384well microtiter plate (Gr...				US Patent US9777004 (2017) BindingDB Entry DOI: 10.7270/Q2B27XDM
					More data for this Ligand-Target Pair
Isoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D] (Homo sapiens (Human))	BDBM343691 (3-(5-Chloro-1-benzofuran-2-yl)-6-{2-[(2S)-pyrrolid...) Show SMILES Clc1ccc2oc(cc2c1)-c1cnc2ccc(OCC[C@@H]3CCCN3)nn12 |r| Show InChI InChI=1S/C20H19ClN4O2/c21-14-3-4-17-13(10-14)11-18(27-17)16-12-23-19-5-6-20(24-25(16)19)26-9-7-15-2-1-8-22-15/h3-6,10-12,15,22H,1-2,7-9H2/t15-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent					Assay Description For the assay 50 nL of a 100fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384well microtiter plate (Gr...				US Patent US9777004 (2017) BindingDB Entry DOI: 10.7270/Q2B27XDM
					More data for this Ligand-Target Pair
Isoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D] (Homo sapiens (Human))	BDBM343693 (N-(2-{[3-(1-Benzofuran-2-yl)imidazo[1,2-b]pyridazi...) Show SMILES CC(C)CNCC(Oc1ccc2ncc(-c3cc4ccccc4o3)n2n1)c1ccccc1 |w:6.29| Show InChI InChI=1S/C26H26N4O2/c1-18(2)15-27-17-24(19-8-4-3-5-9-19)32-26-13-12-25-28-16-21(30(25)29-26)23-14-20-10-6-7-11-22(20)31-23/h3-14,16,18,24,27H,15,17H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	59	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent					Assay Description For the assay 50 nL of a 100fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384well microtiter plate (Gr...				US Patent US9777004 (2017) BindingDB Entry DOI: 10.7270/Q2B27XDM
					More data for this Ligand-Target Pair
Isoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D] (Homo sapiens (Human))	BDBM343694 ((-)-2-{[3-(1-Benzofuran-2-yl)imidazo[1,2-b]pyridaz...) Show SMILES CNCC(Oc1ccc2ncc(-c3cc4ccccc4o3)n2n1)c1ccccc1 Show InChI InChI=1S/C23H20N4O2/c1-24-15-21(16-7-3-2-4-8-16)29-23-12-11-22-25-14-18(27(22)26-23)20-13-17-9-5-6-10-19(17)28-20/h2-14,21,24H,15H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	98	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent					Assay Description For the assay 50 nL of a 100fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384well microtiter plate (Gr...				US Patent US9777004 (2017) BindingDB Entry DOI: 10.7270/Q2B27XDM
					More data for this Ligand-Target Pair
Isoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D] (Homo sapiens (Human))	BDBM343695 (N-(2-{[3-(1-Benzofuran-2-yl)imidazo[1,2-b]pyridazi...) Show SMILES CC(C)(C)CNCC(Oc1ccc2ncc(-c3cc4ccccc4o3)n2n1)c1ccccc1 |w:8.7| Show InChI InChI=1S/C27H28N4O2/c1-27(2,3)18-28-17-24(19-9-5-4-6-10-19)33-26-14-13-25-29-16-21(31(25)30-26)23-15-20-11-7-8-12-22(20)32-23/h4-16,24,28H,17-18H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	227	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent					Assay Description For the assay 50 nL of a 100fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384well microtiter plate (Gr...				US Patent US9777004 (2017) BindingDB Entry DOI: 10.7270/Q2B27XDM
					More data for this Ligand-Target Pair