Compile Data Set for Download or QSAR

Found 25 hits Enz. Inhib. hit(s) with all data for assayid = 7 entry = 50014197   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50139391 ((R)-4-(2-(2-(2-methylpyrrolidin-1-yl)ethyl)benzofu...) Show SMILES C[C@@H]1CCCN1CCc1cc2cc(ccc2o1)-c1ccc(cc1)C#N |r| Show InChI InChI=1S/C22H22N2O/c1-16-3-2-11-24(16)12-10-21-14-20-13-19(8-9-22(20)25-21)18-6-4-17(15-23)5-7-18/h4-9,13-14,16H,2-3,10-12H2,1H3/t16-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	0.450	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency was determined by displacement of [3H]N-alpha-methyl histamine from cloned human histamine H3 receptor expressed in C6 cells				Bioorg Med Chem Lett 14: 689-93 (2004) BindingDB Entry DOI: 10.7270/Q20C4V5H
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50139374 ((6-{2-[2-((R)-2-Methyl-pyrrolidin-1-yl)-ethyl]-ben...) Show SMILES C[C@@H]1CCCN1CCc1cc2cc(ccc2o1)-c1ccc(cn1)C(=O)N1CCOCC1 Show InChI InChI=1S/C25H29N3O3/c1-18-3-2-9-27(18)10-8-22-16-21-15-19(5-7-24(21)31-22)23-6-4-20(17-26-23)25(29)28-11-13-30-14-12-28/h4-7,15-18H,2-3,8-14H2,1H3/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.550	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency was determined by displacement of [3H]N-alpha-methyl histamine from cloned human histamine H3 receptor expressed in C6 cells				Bioorg Med Chem Lett 14: 689-93 (2004) BindingDB Entry DOI: 10.7270/Q20C4V5H
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50139389 (4-{2-[2-(2-Methyl-pyrrolidin-1-yl)-ethyl]-benzofur...) Show SMILES CC1CCCN1CCc1cc2cc(ccc2o1)-c1ccc(cc1)C#N Show InChI InChI=1S/C22H22N2O/c1-16-3-2-11-24(16)12-10-21-14-20-13-19(8-9-22(20)25-21)18-6-4-17(15-23)5-7-18/h4-9,13-14,16H,2-3,10-12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	0.950	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency was determined by displacement of [3H]N-alpha-methyl histamine from cloned human histamine H3 receptor expressed in C6 cells				Bioorg Med Chem Lett 14: 689-93 (2004) BindingDB Entry DOI: 10.7270/Q20C4V5H
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50139408 ((4-{2-[2-((S)-2-Hydroxymethyl-pyrrolidin-1-yl)-eth...) Show SMILES OC[C@@H]1CCCN1CCc1cc2cc(ccc2o1)-c1ccc(cc1)C(=O)N1CCOCC1 Show InChI InChI=1S/C26H30N2O4/c29-18-23-2-1-10-27(23)11-9-24-17-22-16-21(7-8-25(22)32-24)19-3-5-20(6-4-19)26(30)28-12-14-31-15-13-28/h3-8,16-17,23,29H,1-2,9-15,18H2/t23-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency was determined by displacement of [3H]N-alpha-methyl histamine from cloned human histamine H3 receptor expressed in C6 cells				Bioorg Med Chem Lett 14: 689-93 (2004) BindingDB Entry DOI: 10.7270/Q20C4V5H
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50139380 (4-{2-[2-((S)-2-Hydroxymethyl-pyrrolidin-1-yl)-ethy...) Show SMILES OC[C@@H]1CCCN1CCc1cc2cc(ccc2o1)-c1ccc(cc1)C#N Show InChI InChI=1S/C22H22N2O2/c23-14-16-3-5-17(6-4-16)18-7-8-22-19(12-18)13-21(26-22)9-11-24-10-1-2-20(24)15-25/h3-8,12-13,20,25H,1-2,9-11,15H2/t20-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency was determined by displacement of [3H]N-alpha-methyl histamine from cloned human histamine H3 receptor expressed in C6 cells				Bioorg Med Chem Lett 14: 689-93 (2004) BindingDB Entry DOI: 10.7270/Q20C4V5H
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50139383 ((4-{2-[2-((2R,5R)-2,5-Dimethyl-pyrrolidin-1-yl)-et...) Show SMILES C[C@@H]1CC[C@@H](C)N1CCc1cc2cc(ccc2o1)-c1ccc(cc1)C(=O)N1CCOCC1 Show InChI InChI=1S/C27H32N2O3/c1-19-3-4-20(2)29(19)12-11-25-18-24-17-23(9-10-26(24)32-25)21-5-7-22(8-6-21)27(30)28-13-15-31-16-14-28/h5-10,17-20H,3-4,11-16H2,1-2H3/t19-,20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency was determined by displacement of [3H]N-alpha-methyl histamine from cloned human histamine H3 receptor expressed in C6 cells				Bioorg Med Chem Lett 14: 689-93 (2004) BindingDB Entry DOI: 10.7270/Q20C4V5H
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50139388 (CHEMBL159565 | Morpholin-4-yl-{4-[2-(2-piperidin-1...) Show SMILES O=C(N1CCOCC1)c1ccc(cc1)-c1ccc2oc(CCN3CCCCC3)cc2c1 Show InChI InChI=1S/C26H30N2O3/c29-26(28-14-16-30-17-15-28)21-6-4-20(5-7-21)22-8-9-25-23(18-22)19-24(31-25)10-13-27-11-2-1-3-12-27/h4-9,18-19H,1-3,10-17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency was determined by displacement of [3H]N-alpha-methyl histamine from cloned human histamine H3 receptor expressed in C6 cells				Bioorg Med Chem Lett 14: 689-93 (2004) BindingDB Entry DOI: 10.7270/Q20C4V5H
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50139407 (4-{2-[2-((2R,6S)-2,6-Dimethyl-piperidin-1-yl)-ethy...) Show SMILES C[C@H]1CCC[C@@H](C)N1CCc1cc2cc(ccc2o1)-c1ccc(cc1)C#N Show InChI InChI=1S/C24H26N2O/c1-17-4-3-5-18(2)26(17)13-12-23-15-22-14-21(10-11-24(22)27-23)20-8-6-19(16-25)7-9-20/h6-11,14-15,17-18H,3-5,12-13H2,1-2H3/t17-,18+	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency was determined by displacement of [3H]N-alpha-methyl histamine from cloned human histamine H3 receptor expressed in C6 cells				Bioorg Med Chem Lett 14: 689-93 (2004) BindingDB Entry DOI: 10.7270/Q20C4V5H
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50139402 ((4-{2-[2-(2-Methyl-piperidin-1-yl)-ethyl]-benzofur...) Show SMILES CC1CCCCN1CCc1cc2cc(ccc2o1)-c1ccc(cc1)C(=O)N1CCOCC1 Show InChI InChI=1S/C27H32N2O3/c1-20-4-2-3-12-28(20)13-11-25-19-24-18-23(9-10-26(24)32-25)21-5-7-22(8-6-21)27(30)29-14-16-31-17-15-29/h5-10,18-20H,2-4,11-17H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency was determined by displacement of [3H]N-alpha-methyl histamine from cloned human histamine H3 receptor expressed in C6 cells				Bioorg Med Chem Lett 14: 689-93 (2004) BindingDB Entry DOI: 10.7270/Q20C4V5H
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50139385 (CHEMBL346562 | {4-[2-(2-Azepan-1-yl-ethyl)-benzofu...) Show SMILES O=C(N1CCOCC1)c1ccc(cc1)-c1ccc2oc(CCN3CCCCCC3)cc2c1 Show InChI InChI=1S/C27H32N2O3/c30-27(29-15-17-31-18-16-29)22-7-5-21(6-8-22)23-9-10-26-24(19-23)20-25(32-26)11-14-28-12-3-1-2-4-13-28/h5-10,19-20H,1-4,11-18H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency was determined by displacement of [3H]N-alpha-methyl histamine from cloned human histamine H3 receptor expressed in C6 cells				Bioorg Med Chem Lett 14: 689-93 (2004) BindingDB Entry DOI: 10.7270/Q20C4V5H
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50139377 (4-[2-(2-Pyrrolidin-1-yl-ethyl)-benzofuran-5-yl]-be...) Show SMILES N#Cc1ccc(cc1)-c1ccc2oc(CCN3CCCC3)cc2c1 Show InChI InChI=1S/C21H20N2O/c22-15-16-3-5-17(6-4-16)18-7-8-21-19(13-18)14-20(24-21)9-12-23-10-1-2-11-23/h3-8,13-14H,1-2,9-12H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency was determined by displacement of [3H]N-alpha-methyl histamine from cloned human histamine H3 receptor expressed in C6 cells				Bioorg Med Chem Lett 14: 689-93 (2004) BindingDB Entry DOI: 10.7270/Q20C4V5H
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50139387 (4-{2-[2-((2R,5R)-2,5-Dimethyl-pyrrolidin-1-yl)-eth...) Show SMILES C[C@@H]1CC[C@@H](C)N1CCc1cc2cc(ccc2o1)-c1ccc(cc1)C#N Show InChI InChI=1S/C23H24N2O/c1-16-3-4-17(2)25(16)12-11-22-14-21-13-20(9-10-23(21)26-22)19-7-5-18(15-24)6-8-19/h5-10,13-14,16-17H,3-4,11-12H2,1-2H3/t16-,17-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency was determined by displacement of [3H]N-alpha-methyl histamine from cloned human histamine H3 receptor expressed in C6 cells				Bioorg Med Chem Lett 14: 689-93 (2004) BindingDB Entry DOI: 10.7270/Q20C4V5H
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50139410 ((6-{2-[2-((2R,6S)-2,6-Dimethyl-piperidin-1-yl)-eth...) Show SMILES C[C@H]1CCC[C@@H](C)N1CCc1cc2cc(ccc2o1)-c1ccc(cn1)C(=O)N1CCOCC1 Show InChI InChI=1S/C27H33N3O3/c1-19-4-3-5-20(2)30(19)11-10-24-17-23-16-21(7-9-26(23)33-24)25-8-6-22(18-28-25)27(31)29-12-14-32-15-13-29/h6-9,16-20H,3-5,10-15H2,1-2H3/t19-,20+	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency was determined by displacement of [3H]N-alpha-methyl histamine from cloned human histamine H3 receptor expressed in C6 cells				Bioorg Med Chem Lett 14: 689-93 (2004) BindingDB Entry DOI: 10.7270/Q20C4V5H
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50139394 (4-{2-[2-(2-Methyl-piperidin-1-yl)-ethyl]-benzofura...) Show SMILES CC1CCCCN1CCc1cc2cc(ccc2o1)-c1ccc(cc1)C#N Show InChI InChI=1S/C23H24N2O/c1-17-4-2-3-12-25(17)13-11-22-15-21-14-20(9-10-23(21)26-22)19-7-5-18(16-24)6-8-19/h5-10,14-15,17H,2-4,11-13H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency was determined by displacement of [3H]N-alpha-methyl histamine from cloned human histamine H3 receptor expressed in C6 cells				Bioorg Med Chem Lett 14: 689-93 (2004) BindingDB Entry DOI: 10.7270/Q20C4V5H
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50139411 ((6-{2-[2-((2R,5R)-2,5-Dimethyl-pyrrolidin-1-yl)-et...) Show SMILES C[C@@H]1CC[C@@H](C)N1CCc1cc2cc(ccc2o1)-c1ccc(cn1)C(=O)N1CCOCC1 Show InChI InChI=1S/C26H31N3O3/c1-18-3-4-19(2)29(18)10-9-23-16-22-15-20(6-8-25(22)32-23)24-7-5-21(17-27-24)26(30)28-11-13-31-14-12-28/h5-8,15-19H,3-4,9-14H2,1-2H3/t18-,19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency was determined by displacement of [3H]N-alpha-methyl histamine from cloned human histamine H3 receptor expressed in C6 cells				Bioorg Med Chem Lett 14: 689-93 (2004) BindingDB Entry DOI: 10.7270/Q20C4V5H
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50404283 (CHEMBL2112921) Show SMILES O[C@@H]1CCN(CCc2cc3cc(ccc3o2)-c2ccc(cc2)C(=O)N2CCOCC2)C1 |r| Show InChI InChI=1S/C25H28N2O4/c28-22-7-9-26(17-22)10-8-23-16-21-15-20(5-6-24(21)31-23)18-1-3-19(4-2-18)25(29)27-11-13-30-14-12-27/h1-6,15-16,22,28H,7-14,17H2/t22-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	6.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency was determined by displacement of [3H]N-alpha-methyl histamine from cloned human histamine H3 receptor expressed in C6 cells				Bioorg Med Chem Lett 14: 689-93 (2004) BindingDB Entry DOI: 10.7270/Q20C4V5H
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50139378 (4-{2-[2-(3-Hydroxy-pyrrolidin-1-yl)-ethyl]-benzofu...) Show SMILES OC1CCN(CCc2cc3cc(ccc3o2)-c2ccc(cc2)C#N)C1 Show InChI InChI=1S/C21H20N2O2/c22-13-15-1-3-16(4-2-15)17-5-6-21-18(11-17)12-20(25-21)8-10-23-9-7-19(24)14-23/h1-6,11-12,19,24H,7-10,14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	8.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency was determined by displacement of [3H]N-alpha-methyl histamine from cloned human histamine H3 receptor expressed in C6 cells				Bioorg Med Chem Lett 14: 689-93 (2004) BindingDB Entry DOI: 10.7270/Q20C4V5H
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50139381 (4-[2-(2-Piperidin-1-yl-ethyl)-benzofuran-5-yl]-ben...) Show SMILES N#Cc1ccc(cc1)-c1ccc2oc(CCN3CCCCC3)cc2c1 Show InChI InChI=1S/C22H22N2O/c23-16-17-4-6-18(7-5-17)19-8-9-22-20(14-19)15-21(25-22)10-13-24-11-2-1-3-12-24/h4-9,14-15H,1-3,10-13H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	8.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency was determined by displacement of [3H]N-alpha-methyl histamine from cloned human histamine H3 receptor expressed in C6 cells				Bioorg Med Chem Lett 14: 689-93 (2004) BindingDB Entry DOI: 10.7270/Q20C4V5H
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50139396 (4-{2-[2-(3,6-Dihydro-2H-pyridin-1-yl)-ethyl]-benzo...) Show SMILES N#Cc1ccc(cc1)-c1ccc2oc(CCN3CCC=CC3)cc2c1 |c:20| Show InChI InChI=1S/C22H20N2O/c23-16-17-4-6-18(7-5-17)19-8-9-22-20(14-19)15-21(25-22)10-13-24-11-2-1-3-12-24/h1-2,4-9,14-15H,3,10-13H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency was determined by displacement of [3H]N-alpha-methyl histamine from cloned human histamine H3 receptor expressed in C6 cells				Bioorg Med Chem Lett 14: 689-93 (2004) BindingDB Entry DOI: 10.7270/Q20C4V5H
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50139400 (4-{2-[2-((R)-3-Dimethylamino-pyrrolidin-1-yl)-ethy...) Show SMILES CN(C)[C@@H]1CCN(CCc2cc3cc(ccc3o2)-c2ccc(cc2)C#N)C1 Show InChI InChI=1S/C23H25N3O/c1-25(2)21-9-11-26(16-21)12-10-22-14-20-13-19(7-8-23(20)27-22)18-5-3-17(15-24)4-6-18/h3-8,13-14,21H,9-12,16H2,1-2H3/t21-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency was determined by displacement of [3H]N-alpha-methyl histamine from cloned human histamine H3 receptor expressed in C6 cells				Bioorg Med Chem Lett 14: 689-93 (2004) BindingDB Entry DOI: 10.7270/Q20C4V5H
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50139406 (CHEMBL159858 | {6-[2-(2-Azepan-1-yl-ethyl)-benzofu...) Show SMILES O=C(N1CCOCC1)c1ccc(nc1)-c1ccc2oc(CCN3CCCCCC3)cc2c1 Show InChI InChI=1S/C26H31N3O3/c30-26(29-13-15-31-16-14-29)21-5-7-24(27-19-21)20-6-8-25-22(17-20)18-23(32-25)9-12-28-10-3-1-2-4-11-28/h5-8,17-19H,1-4,9-16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency was determined by displacement of [3H]N-alpha-methyl histamine from cloned human histamine H3 receptor expressed in C6 cells				Bioorg Med Chem Lett 14: 689-93 (2004) BindingDB Entry DOI: 10.7270/Q20C4V5H
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50139405 ((4-{2-[2-(4-Methyl-piperidin-1-yl)-ethyl]-benzofur...) Show SMILES CC1CCN(CCc2cc3cc(ccc3o2)-c2ccc(cc2)C(=O)N2CCOCC2)CC1 Show InChI InChI=1S/C27H32N2O3/c1-20-8-11-28(12-9-20)13-10-25-19-24-18-23(6-7-26(24)32-25)21-2-4-22(5-3-21)27(30)29-14-16-31-17-15-29/h2-7,18-20H,8-17H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency was determined by displacement of [3H]N-alpha-methyl histamine from cloned human histamine H3 receptor expressed in C6 cells				Bioorg Med Chem Lett 14: 689-93 (2004) BindingDB Entry DOI: 10.7270/Q20C4V5H
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50139390 (4-{2-[2-((R)-2-Hydroxymethyl-pyrrolidin-1-yl)-ethy...) Show SMILES OC[C@H]1CCCN1CCc1cc2cc(ccc2o1)-c1ccc(cc1)C#N Show InChI InChI=1S/C22H22N2O2/c23-14-16-3-5-17(6-4-16)18-7-8-22-19(12-18)13-21(26-22)9-11-24-10-1-2-20(24)15-25/h3-8,12-13,20,25H,1-2,9-11,15H2/t20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency was determined by displacement of [3H]N-alpha-methyl histamine from cloned human histamine H3 receptor expressed in C6 cells				Bioorg Med Chem Lett 14: 689-93 (2004) BindingDB Entry DOI: 10.7270/Q20C4V5H
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50139401 (4-{2-[2-((S)-3-Dimethylamino-pyrrolidin-1-yl)-ethy...) Show SMILES CN(C)[C@H]1CCN(CCc2cc3cc(ccc3o2)-c2ccc(cc2)C#N)C1 Show InChI InChI=1S/C23H25N3O/c1-25(2)21-9-11-26(16-21)12-10-22-14-20-13-19(7-8-23(20)27-22)18-5-3-17(15-24)4-6-18/h3-8,13-14,21H,9-12,16H2,1-2H3/t21-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	49	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency was determined by displacement of [3H]N-alpha-methyl histamine from cloned human histamine H3 receptor expressed in C6 cells				Bioorg Med Chem Lett 14: 689-93 (2004) BindingDB Entry DOI: 10.7270/Q20C4V5H
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50139395 (((R)-1-{2-[5-(4-Cyano-phenyl)-benzofuran-2-yl]-eth...) Show SMILES OC(=O)C[C@H]1CCCN1CCc1cc2cc(ccc2o1)-c1ccc(cc1)C#N Show InChI InChI=1S/C23H22N2O3/c24-15-16-3-5-17(6-4-16)18-7-8-22-19(12-18)13-21(28-22)9-11-25-10-1-2-20(25)14-23(26)27/h3-8,12-13,20H,1-2,9-11,14H2,(H,26,27)/t20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding potency was determined by displacement of [3H]N-alpha-methyl histamine from cloned human histamine H3 receptor expressed in C6 cells				Bioorg Med Chem Lett 14: 689-93 (2004) BindingDB Entry DOI: 10.7270/Q20C4V5H
					More data for this Ligand-Target Pair