Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Phosphoethanolamine N-methyltransferase 2 (Caenorhabditis elegans) | BDBM50034220 (2-(((Hexadecyloxy)hydroxyphosphinyl)oxy)-N,N,N-tri...) | PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.25E+4 | n/a | n/a | n/a | n/a | 8.0 | 25 |
Washington University | Assay Description A radiochemical assay was used to measure enzymatic activity. | J Biol Chem 286: 38060-8 (2011) Article DOI: 10.1074/jbc.M111.290619 BindingDB Entry DOI: 10.7270/Q2GF0S39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphoethanolamine N-methyltransferase 1 (Caenorhabditis elegans) | BDBM92471 (Sinefungin) | UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 3.38E+4 | n/a | n/a | n/a | n/a | 8.0 | 25 |
Washington University | Assay Description A radiochemical assay was used to measure enzymatic activity. | J Biol Chem 286: 38060-8 (2011) Article DOI: 10.1074/jbc.M111.290619 BindingDB Entry DOI: 10.7270/Q2GF0S39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphoethanolamine N-methyltransferase (Plasmodium falciparum) | BDBM50462274 (CHEMBL4246869) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.43E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Siena Curated by ChEMBL | Assay Description Inhibition of plasmodium falciparum phosphoethanolamine N-methyltransferase expressed in Escherichia coli using phosphoethanolamine as substrate and ... | Eur J Med Chem 150: 698-718 (2018) Article DOI: 10.1016/j.ejmech.2018.03.024 BindingDB Entry DOI: 10.7270/Q2PC3518 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphoethanolamine N-methyltransferase 2 (Caenorhabditis elegans) | BDBM92471 (Sinefungin) | PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 9.15E+4 | n/a | n/a | n/a | n/a | 8.0 | 25 |
Washington University | Assay Description A radiochemical assay was used to measure enzymatic activity. | J Biol Chem 286: 38060-8 (2011) Article DOI: 10.1074/jbc.M111.290619 BindingDB Entry DOI: 10.7270/Q2GF0S39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphoethanolamine N-methyltransferase 1 (Caenorhabditis elegans) | BDBM50034220 (2-(((Hexadecyloxy)hydroxyphosphinyl)oxy)-N,N,N-tri...) | UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.25E+5 | n/a | n/a | n/a | n/a | 8.0 | 25 |
Washington University | Assay Description A radiochemical assay was used to measure enzymatic activity. | J Biol Chem 286: 38060-8 (2011) Article DOI: 10.1074/jbc.M111.290619 BindingDB Entry DOI: 10.7270/Q2GF0S39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphoethanolamine N-methyltransferase (Plasmodium falciparum) | BDBM50149893 (4-(6-Methoxy-quinolin-8-ylamino)-pentyl-ammonium |...) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.60E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Washington University Curated by ChEMBL | Assay Description Inhibition of Plasmodium falciparum phosphoethanolamine methyltransferase using phospethanolamine as substrate by radiochemical assay in presence of ... | Bioorg Med Chem Lett 22: 4990-3 (2012) Article DOI: 10.1016/j.bmcl.2012.06.032 BindingDB Entry DOI: 10.7270/Q29G5NWN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphoethanolamine N-methyltransferase (Plasmodium falciparum) | BDBM22985 (Aralen | CHEMBL76 | CHLOROQUINE PHOSPHATE | Chloro...) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 5.54E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Washington University Curated by ChEMBL | Assay Description Inhibition of Plasmodium falciparum phosphoethanolamine methyltransferase using phospethanolamine as substrate by radiochemical assay in presence of ... | Bioorg Med Chem Lett 22: 4990-3 (2012) Article DOI: 10.1016/j.bmcl.2012.06.032 BindingDB Entry DOI: 10.7270/Q29G5NWN | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
Phosphoethanolamine N-methyltransferase (Plasmodium falciparum) | BDBM50041457 (4-[(7-chloroquinolin-4-yl)amino]-2-[(diethylamino)...) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 1.35E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Washington University Curated by ChEMBL | Assay Description Inhibition of Plasmodium falciparum phosphoethanolamine methyltransferase using phospethanolamine as substrate by radiochemical assay in presence of ... | Bioorg Med Chem Lett 22: 4990-3 (2012) Article DOI: 10.1016/j.bmcl.2012.06.032 BindingDB Entry DOI: 10.7270/Q29G5NWN | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Phosphoethanolamine N-methyltransferase 2 (Caenorhabditis elegans) | BDBM50041457 (4-[(7-chloroquinolin-4-yl)amino]-2-[(diethylamino)...) | PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 3.10E+6 | n/a | n/a | n/a | n/a | 8.0 | 25 |
Washington University | Assay Description A radiochemical assay was used to measure enzymatic activity. | J Biol Chem 286: 38060-8 (2011) Article DOI: 10.1074/jbc.M111.290619 BindingDB Entry DOI: 10.7270/Q2GF0S39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphoethanolamine N-methyltransferase 1 (Caenorhabditis elegans) | BDBM50041457 (4-[(7-chloroquinolin-4-yl)amino]-2-[(diethylamino)...) | UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 3.40E+6 | n/a | n/a | n/a | n/a | 8.0 | 25 |
Washington University | Assay Description A radiochemical assay was used to measure enzymatic activity. | J Biol Chem 286: 38060-8 (2011) Article DOI: 10.1074/jbc.M111.290619 BindingDB Entry DOI: 10.7270/Q2GF0S39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphoethanolamine N-methyltransferase 2 (Caenorhabditis elegans) | BDBM8961 (1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...) | PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 3.50E+6 | n/a | n/a | n/a | n/a | 8.0 | 25 |
Washington University | Assay Description A radiochemical assay was used to measure enzymatic activity. | J Biol Chem 286: 38060-8 (2011) Article DOI: 10.1074/jbc.M111.290619 BindingDB Entry DOI: 10.7270/Q2GF0S39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphoethanolamine N-methyltransferase 2 (Caenorhabditis elegans) | BDBM50017674 ((2-Benzhydryloxy-ethyl)-dimethyl-amine | 2-(benzhy...) | PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.30E+7 | n/a | n/a | n/a | n/a | 8.0 | 25 |
Washington University | Assay Description A radiochemical assay was used to measure enzymatic activity. | J Biol Chem 286: 38060-8 (2011) Article DOI: 10.1074/jbc.M111.290619 BindingDB Entry DOI: 10.7270/Q2GF0S39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphoethanolamine N-methyltransferase 1 (Caenorhabditis elegans) | BDBM8961 (1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...) | UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 2.34E+7 | n/a | n/a | n/a | n/a | 8.0 | 25 |
Washington University | Assay Description A radiochemical assay was used to measure enzymatic activity. | J Biol Chem 286: 38060-8 (2011) Article DOI: 10.1074/jbc.M111.290619 BindingDB Entry DOI: 10.7270/Q2GF0S39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphoethanolamine N-methyltransferase 1 (Caenorhabditis elegans) | BDBM28422 ((2S)-2-amino-4-({[(2S,3S,4R,5R)-5-(6-amino-9H-puri...) | UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase MCE KEGG MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | 1.14E+4 | n/a | n/a | n/a | 7.5 | 15 |
Washington University | Assay Description For standard ITC analysis of ligand binding, proteins were dialyzed overnight in 25 mm Hepes (pH 7.5), 100 mm NaCl, 5 mm ??-mercaptoethanol, and 5% g... | J Biol Chem 286: 38060-8 (2011) Article DOI: 10.1074/jbc.M111.290619 BindingDB Entry DOI: 10.7270/Q2GF0S39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphoethanolamine N-methyltransferase 1 (Caenorhabditis elegans) | BDBM50308984 (AdoCys | CHEMBL597532 | S-Adenosylhomocysteine) | UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 700 | n/a | n/a | n/a | 7.5 | 5 |
Washington University | Assay Description For standard ITC analysis of ligand binding, proteins were dialyzed overnight in 25 mm Hepes (pH 7.5), 100 mm NaCl, 5 mm ??-mercaptoethanol, and 5% g... | J Biol Chem 286: 38060-8 (2011) Article DOI: 10.1074/jbc.M111.290619 BindingDB Entry DOI: 10.7270/Q2GF0S39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphoethanolamine N-methyltransferase 1 (Caenorhabditis elegans) | BDBM50308984 (AdoCys | CHEMBL597532 | S-Adenosylhomocysteine) | UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 800 | n/a | n/a | n/a | 7.5 | 10 |
Washington University | Assay Description For standard ITC analysis of ligand binding, proteins were dialyzed overnight in 25 mm Hepes (pH 7.5), 100 mm NaCl, 5 mm ??-mercaptoethanol, and 5% g... | J Biol Chem 286: 38060-8 (2011) Article DOI: 10.1074/jbc.M111.290619 BindingDB Entry DOI: 10.7270/Q2GF0S39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphoethanolamine N-methyltransferase 1 (Caenorhabditis elegans) | BDBM50308984 (AdoCys | CHEMBL597532 | S-Adenosylhomocysteine) | UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 1.10E+3 | n/a | n/a | n/a | 7.5 | 15 |
Washington University | Assay Description For standard ITC analysis of ligand binding, proteins were dialyzed overnight in 25 mm Hepes (pH 7.5), 100 mm NaCl, 5 mm ??-mercaptoethanol, and 5% g... | J Biol Chem 286: 38060-8 (2011) Article DOI: 10.1074/jbc.M111.290619 BindingDB Entry DOI: 10.7270/Q2GF0S39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphoethanolamine N-methyltransferase 1 (Caenorhabditis elegans) | BDBM50308984 (AdoCys | CHEMBL597532 | S-Adenosylhomocysteine) | UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 1.60E+3 | n/a | n/a | n/a | 7.5 | 20 |
Washington University | Assay Description For standard ITC analysis of ligand binding, proteins were dialyzed overnight in 25 mm Hepes (pH 7.5), 100 mm NaCl, 5 mm ??-mercaptoethanol, and 5% g... | J Biol Chem 286: 38060-8 (2011) Article DOI: 10.1074/jbc.M111.290619 BindingDB Entry DOI: 10.7270/Q2GF0S39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphoethanolamine N-methyltransferase 1 (Caenorhabditis elegans) | BDBM50308984 (AdoCys | CHEMBL597532 | S-Adenosylhomocysteine) | UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 2.50E+3 | n/a | n/a | n/a | 7.5 | 25 |
Washington University | Assay Description For standard ITC analysis of ligand binding, proteins were dialyzed overnight in 25 mm Hepes (pH 7.5), 100 mm NaCl, 5 mm ??-mercaptoethanol, and 5% g... | J Biol Chem 286: 38060-8 (2011) Article DOI: 10.1074/jbc.M111.290619 BindingDB Entry DOI: 10.7270/Q2GF0S39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphoethanolamine N-methyltransferase 2 (Caenorhabditis elegans) | BDBM50308984 (AdoCys | CHEMBL597532 | S-Adenosylhomocysteine) | PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | 7.5 | 5 |
Washington University | Assay Description For standard ITC analysis of ligand binding, proteins were dialyzed overnight in 25 mm Hepes (pH 7.5), 100 mm NaCl, 5 mm ??-mercaptoethanol, and 5% g... | J Biol Chem 286: 38060-8 (2011) Article DOI: 10.1074/jbc.M111.290619 BindingDB Entry DOI: 10.7270/Q2GF0S39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphoethanolamine N-methyltransferase 2 (Caenorhabditis elegans) | BDBM50308984 (AdoCys | CHEMBL597532 | S-Adenosylhomocysteine) | PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 2.50E+3 | n/a | n/a | n/a | 7.5 | 10 |
Washington University | Assay Description For standard ITC analysis of ligand binding, proteins were dialyzed overnight in 25 mm Hepes (pH 7.5), 100 mm NaCl, 5 mm ??-mercaptoethanol, and 5% g... | J Biol Chem 286: 38060-8 (2011) Article DOI: 10.1074/jbc.M111.290619 BindingDB Entry DOI: 10.7270/Q2GF0S39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphoethanolamine N-methyltransferase 2 (Caenorhabditis elegans) | BDBM50308984 (AdoCys | CHEMBL597532 | S-Adenosylhomocysteine) | PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 3.00E+3 | n/a | n/a | n/a | 7.5 | 15 |
Washington University | Assay Description For standard ITC analysis of ligand binding, proteins were dialyzed overnight in 25 mm Hepes (pH 7.5), 100 mm NaCl, 5 mm ??-mercaptoethanol, and 5% g... | J Biol Chem 286: 38060-8 (2011) Article DOI: 10.1074/jbc.M111.290619 BindingDB Entry DOI: 10.7270/Q2GF0S39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphoethanolamine N-methyltransferase 2 (Caenorhabditis elegans) | BDBM50308984 (AdoCys | CHEMBL597532 | S-Adenosylhomocysteine) | PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 4.20E+3 | n/a | n/a | n/a | 7.5 | 20 |
Washington University | Assay Description For standard ITC analysis of ligand binding, proteins were dialyzed overnight in 25 mm Hepes (pH 7.5), 100 mm NaCl, 5 mm ??-mercaptoethanol, and 5% g... | J Biol Chem 286: 38060-8 (2011) Article DOI: 10.1074/jbc.M111.290619 BindingDB Entry DOI: 10.7270/Q2GF0S39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphoethanolamine N-methyltransferase 2 (Caenorhabditis elegans) | BDBM50308984 (AdoCys | CHEMBL597532 | S-Adenosylhomocysteine) | PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 5.40E+3 | n/a | n/a | n/a | 7.5 | 25 |
Washington University | Assay Description For standard ITC analysis of ligand binding, proteins were dialyzed overnight in 25 mm Hepes (pH 7.5), 100 mm NaCl, 5 mm ??-mercaptoethanol, and 5% g... | J Biol Chem 286: 38060-8 (2011) Article DOI: 10.1074/jbc.M111.290619 BindingDB Entry DOI: 10.7270/Q2GF0S39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphoethanolamine N-methyltransferase 1 (Caenorhabditis elegans) | BDBM28422 ((2S)-2-amino-4-({[(2S,3S,4R,5R)-5-(6-amino-9H-puri...) | UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase MCE KEGG MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | 4.72E+4 | n/a | n/a | n/a | 7.5 | 4 |
Washington University | Assay Description For standard ITC analysis of ligand binding, proteins were dialyzed overnight in 25 mm Hepes (pH 7.5), 100 mm NaCl, 5 mm ??-mercaptoethanol, and 5% g... | J Biol Chem 286: 38060-8 (2011) Article DOI: 10.1074/jbc.M111.290619 BindingDB Entry DOI: 10.7270/Q2GF0S39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphoethanolamine N-methyltransferase 1 (Caenorhabditis elegans) | BDBM28422 ((2S)-2-amino-4-({[(2S,3S,4R,5R)-5-(6-amino-9H-puri...) | UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase MCE KEGG MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | 1.91E+4 | n/a | n/a | n/a | 7.5 | 4 |
Washington University | Assay Description For standard ITC analysis of ligand binding, proteins were dialyzed overnight in 25 mm Hepes (pH 7.5), 100 mm NaCl, 5 mm ??-mercaptoethanol, and 5% g... | J Biol Chem 286: 38060-8 (2011) Article DOI: 10.1074/jbc.M111.290619 BindingDB Entry DOI: 10.7270/Q2GF0S39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphoethanolamine N-methyltransferase 1 (Caenorhabditis elegans) | BDBM28422 ((2S)-2-amino-4-({[(2S,3S,4R,5R)-5-(6-amino-9H-puri...) | UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase MCE KEGG MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | 1.07E+4 | n/a | n/a | n/a | 7.5 | 4 |
Washington University | Assay Description For standard ITC analysis of ligand binding, proteins were dialyzed overnight in 25 mm Hepes (pH 7.5), 100 mm NaCl, 5 mm ??-mercaptoethanol, and 5% g... | J Biol Chem 286: 38060-8 (2011) Article DOI: 10.1074/jbc.M111.290619 BindingDB Entry DOI: 10.7270/Q2GF0S39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphoethanolamine N-methyltransferase 1 (Caenorhabditis elegans) | BDBM28422 ((2S)-2-amino-4-({[(2S,3S,4R,5R)-5-(6-amino-9H-puri...) | UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase MCE KEGG MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | 5.80E+3 | n/a | n/a | n/a | 7.5 | 4 |
Washington University | Assay Description For standard ITC analysis of ligand binding, proteins were dialyzed overnight in 25 mm Hepes (pH 7.5), 100 mm NaCl, 5 mm ??-mercaptoethanol, and 5% g... | J Biol Chem 286: 38060-8 (2011) Article DOI: 10.1074/jbc.M111.290619 BindingDB Entry DOI: 10.7270/Q2GF0S39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphoethanolamine N-methyltransferase 1 (Caenorhabditis elegans) | BDBM50308984 (AdoCys | CHEMBL597532 | S-Adenosylhomocysteine) | UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 2.90E+3 | n/a | n/a | n/a | 7.5 | 4 |
Washington University | Assay Description For standard ITC analysis of ligand binding, proteins were dialyzed overnight in 25 mm Hepes (pH 7.5), 100 mm NaCl, 5 mm ??-mercaptoethanol, and 5% g... | J Biol Chem 286: 38060-8 (2011) Article DOI: 10.1074/jbc.M111.290619 BindingDB Entry DOI: 10.7270/Q2GF0S39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphoethanolamine N-methyltransferase 1 (Caenorhabditis elegans) | BDBM50308984 (AdoCys | CHEMBL597532 | S-Adenosylhomocysteine) | UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 2.20E+3 | n/a | n/a | n/a | 7.5 | 4 |
Washington University | Assay Description For standard ITC analysis of ligand binding, proteins were dialyzed overnight in 25 mm Hepes (pH 7.5), 100 mm NaCl, 5 mm ??-mercaptoethanol, and 5% g... | J Biol Chem 286: 38060-8 (2011) Article DOI: 10.1074/jbc.M111.290619 BindingDB Entry DOI: 10.7270/Q2GF0S39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphoethanolamine N-methyltransferase 1 (Caenorhabditis elegans) | BDBM50308984 (AdoCys | CHEMBL597532 | S-Adenosylhomocysteine) | UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 1.30E+3 | n/a | n/a | n/a | 7.5 | 4 |
Washington University | Assay Description For standard ITC analysis of ligand binding, proteins were dialyzed overnight in 25 mm Hepes (pH 7.5), 100 mm NaCl, 5 mm ??-mercaptoethanol, and 5% g... | J Biol Chem 286: 38060-8 (2011) Article DOI: 10.1074/jbc.M111.290619 BindingDB Entry DOI: 10.7270/Q2GF0S39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphoethanolamine N-methyltransferase 1 (Caenorhabditis elegans) | BDBM50308984 (AdoCys | CHEMBL597532 | S-Adenosylhomocysteine) | UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 900 | n/a | n/a | n/a | 7.5 | 4 |
Washington University | Assay Description For standard ITC analysis of ligand binding, proteins were dialyzed overnight in 25 mm Hepes (pH 7.5), 100 mm NaCl, 5 mm ??-mercaptoethanol, and 5% g... | J Biol Chem 286: 38060-8 (2011) Article DOI: 10.1074/jbc.M111.290619 BindingDB Entry DOI: 10.7270/Q2GF0S39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphoethanolamine N-methyltransferase 2 (Caenorhabditis elegans) | BDBM50308984 (AdoCys | CHEMBL597532 | S-Adenosylhomocysteine) | PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 8.60E+3 | n/a | n/a | n/a | 7.5 | 4 |
Washington University | Assay Description For standard ITC analysis of ligand binding, proteins were dialyzed overnight in 25 mm Hepes (pH 7.5), 100 mm NaCl, 5 mm ??-mercaptoethanol, and 5% g... | J Biol Chem 286: 38060-8 (2011) Article DOI: 10.1074/jbc.M111.290619 BindingDB Entry DOI: 10.7270/Q2GF0S39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphoethanolamine N-methyltransferase 2 (Caenorhabditis elegans) | BDBM50308984 (AdoCys | CHEMBL597532 | S-Adenosylhomocysteine) | PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 6.00E+3 | n/a | n/a | n/a | 7.5 | 4 |
Washington University | Assay Description For standard ITC analysis of ligand binding, proteins were dialyzed overnight in 25 mm Hepes (pH 7.5), 100 mm NaCl, 5 mm ??-mercaptoethanol, and 5% g... | J Biol Chem 286: 38060-8 (2011) Article DOI: 10.1074/jbc.M111.290619 BindingDB Entry DOI: 10.7270/Q2GF0S39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphoethanolamine N-methyltransferase 2 (Caenorhabditis elegans) | BDBM50308984 (AdoCys | CHEMBL597532 | S-Adenosylhomocysteine) | PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 9.30E+3 | n/a | n/a | n/a | 7.5 | 4 |
Washington University | Assay Description For standard ITC analysis of ligand binding, proteins were dialyzed overnight in 25 mm Hepes (pH 7.5), 100 mm NaCl, 5 mm ??-mercaptoethanol, and 5% g... | J Biol Chem 286: 38060-8 (2011) Article DOI: 10.1074/jbc.M111.290619 BindingDB Entry DOI: 10.7270/Q2GF0S39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphoethanolamine N-methyltransferase 2 (Caenorhabditis elegans) | BDBM50308984 (AdoCys | CHEMBL597532 | S-Adenosylhomocysteine) | PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 6.10E+3 | n/a | n/a | n/a | 7.5 | 4 |
Washington University | Assay Description For standard ITC analysis of ligand binding, proteins were dialyzed overnight in 25 mm Hepes (pH 7.5), 100 mm NaCl, 5 mm ??-mercaptoethanol, and 5% g... | J Biol Chem 286: 38060-8 (2011) Article DOI: 10.1074/jbc.M111.290619 BindingDB Entry DOI: 10.7270/Q2GF0S39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphoethanolamine N-methyltransferase 1 (Caenorhabditis elegans) | BDBM28422 ((2S)-2-amino-4-({[(2S,3S,4R,5R)-5-(6-amino-9H-puri...) | UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase MCE KEGG MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | 8.20E+3 | n/a | n/a | n/a | 7.5 | 10 |
Washington University | Assay Description For standard ITC analysis of ligand binding, proteins were dialyzed overnight in 25 mm Hepes (pH 7.5), 100 mm NaCl, 5 mm ??-mercaptoethanol, and 5% g... | J Biol Chem 286: 38060-8 (2011) Article DOI: 10.1074/jbc.M111.290619 BindingDB Entry DOI: 10.7270/Q2GF0S39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphoethanolamine N-methyltransferase 1 (Caenorhabditis elegans) | BDBM28422 ((2S)-2-amino-4-({[(2S,3S,4R,5R)-5-(6-amino-9H-puri...) | UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase MCE KEGG MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | 6.10E+3 | n/a | n/a | n/a | 7.5 | 5 |
Washington University | Assay Description For standard ITC analysis of ligand binding, proteins were dialyzed overnight in 25 mm Hepes (pH 7.5), 100 mm NaCl, 5 mm ??-mercaptoethanol, and 5% g... | J Biol Chem 286: 38060-8 (2011) Article DOI: 10.1074/jbc.M111.290619 BindingDB Entry DOI: 10.7270/Q2GF0S39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphoethanolamine N-methyltransferase 1 (Caenorhabditis elegans) | BDBM28422 ((2S)-2-amino-4-({[(2S,3S,4R,5R)-5-(6-amino-9H-puri...) | UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase MCE KEGG MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | 1.66E+4 | n/a | n/a | n/a | 7.5 | 20 |
Washington University | Assay Description For standard ITC analysis of ligand binding, proteins were dialyzed overnight in 25 mm Hepes (pH 7.5), 100 mm NaCl, 5 mm ??-mercaptoethanol, and 5% g... | J Biol Chem 286: 38060-8 (2011) Article DOI: 10.1074/jbc.M111.290619 BindingDB Entry DOI: 10.7270/Q2GF0S39 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phosphoethanolamine N-methyltransferase 1 (Caenorhabditis elegans) | BDBM28422 ((2S)-2-amino-4-({[(2S,3S,4R,5R)-5-(6-amino-9H-puri...) | UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase MCE KEGG MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | 2.67E+4 | n/a | n/a | n/a | 7.5 | 25 |
Washington University | Assay Description For standard ITC analysis of ligand binding, proteins were dialyzed overnight in 25 mm Hepes (pH 7.5), 100 mm NaCl, 5 mm ??-mercaptoethanol, and 5% g... | J Biol Chem 286: 38060-8 (2011) Article DOI: 10.1074/jbc.M111.290619 BindingDB Entry DOI: 10.7270/Q2GF0S39 | |||||||||||
More data for this Ligand-Target Pair |