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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Seed linoleate 13S-lipoxygenase-1 (Glycine max (soybean)) | BDBM152753 (3-((5-bromo-6-methyl-2-(4-phenylpiperazin-1-yl)pyr...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet  | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >5.00E+5 | n/a | n/a | n/a | n/a | 7.0 | 25 |
Ferdowsi University of Mashhad | Assay Description Linoleic acid and two assay solutions (A and B) were prepared in advance. Solution A was 50 mM 3-(dimethylamino)benzoic acid (DMAB) in a 100 mM phosp... | Chem Biol Drug Des 85: 216-24 (2015) Article DOI: 10.1111/cbdd.12375 BindingDB Entry DOI: 10.7270/Q2ST7NK5 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Seed linoleate 13S-lipoxygenase-1 (Glycine max (soybean)) | BDBM152754 (3-((5-bromo-2-(4-ethylpiperazin-1-yl)-6-methylpyri...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >5.00E+5 | n/a | n/a | n/a | n/a | 7.0 | 25 |
Ferdowsi University of Mashhad | Assay Description Linoleic acid and two assay solutions (A and B) were prepared in advance. Solution A was 50 mM 3-(dimethylamino)benzoic acid (DMAB) in a 100 mM phosp... | Chem Biol Drug Des 85: 216-24 (2015) Article DOI: 10.1111/cbdd.12375 BindingDB Entry DOI: 10.7270/Q2ST7NK5 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Seed linoleate 13S-lipoxygenase-1 (Glycine max (soybean)) | BDBM152755 (3-((5-bromo-6-methyl-2-(pyrrolidin-1-yl)pyrimidin-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >5.00E+5 | n/a | n/a | n/a | n/a | 7.0 | 25 |
Ferdowsi University of Mashhad | Assay Description Linoleic acid and two assay solutions (A and B) were prepared in advance. Solution A was 50 mM 3-(dimethylamino)benzoic acid (DMAB) in a 100 mM phosp... | Chem Biol Drug Des 85: 216-24 (2015) Article DOI: 10.1111/cbdd.12375 BindingDB Entry DOI: 10.7270/Q2ST7NK5 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Seed linoleate 13S-lipoxygenase-1 (Glycine max (soybean)) | BDBM50379791 (METHYLEUGENOL | Methyl eugenol (1)) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.33E+4 | n/a | n/a | n/a | n/a | 7.0 | 25 |
Ferdowsi University of Mashhad | Assay Description Solution A was 50 mm DMAB in an 100 mm phosphate buffer (pH 7.0). Solution B was a mixture of 10 mm MBTH (3 mL) and hemoglobin (5 mg/mL, 3 mL) in 50 ... | Chem Biol Drug Des 88: 460-9 (2016) Article DOI: 10.1111/cbdd.12779 BindingDB Entry DOI: 10.7270/Q2TT4PSF | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Seed linoleate 13S-lipoxygenase-1 (Glycine max (soybean)) | BDBM192756 (1-Allyl-3,5-dimethoxybenzene (2)) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase KEGG PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.32E+4 | n/a | n/a | n/a | n/a | 7.0 | 25 |
Ferdowsi University of Mashhad | Assay Description Solution A was 50 mm DMAB in an 100 mm phosphate buffer (pH 7.0). Solution B was a mixture of 10 mm MBTH (3 mL) and hemoglobin (5 mg/mL, 3 mL) in 50 ... | Chem Biol Drug Des 88: 460-9 (2016) Article DOI: 10.1111/cbdd.12779 BindingDB Entry DOI: 10.7270/Q2TT4PSF | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Seed linoleate 13S-lipoxygenase-1 (Glycine max (soybean)) | BDBM192757 (1,2-dimethoxy-3-(prop-2-en-1-yl)benzene (3) | Meth...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.29E+5 | n/a | n/a | n/a | n/a | 7.0 | 25 |
Ferdowsi University of Mashhad | Assay Description Solution A was 50 mm DMAB in an 100 mm phosphate buffer (pH 7.0). Solution B was a mixture of 10 mm MBTH (3 mL) and hemoglobin (5 mg/mL, 3 mL) in 50 ... | Chem Biol Drug Des 88: 460-9 (2016) Article DOI: 10.1111/cbdd.12779 BindingDB Entry DOI: 10.7270/Q2TT4PSF | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Seed linoleate 13S-lipoxygenase-1 (Glycine max (soybean)) | BDBM192758 (1-Allyl-2,4-dimethoxybenzene (4) | 1-Allyl-2,4-dim...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.14E+4 | n/a | n/a | n/a | n/a | 7.0 | 25 |
Ferdowsi University of Mashhad | Assay Description Solution A was 50 mm DMAB in an 100 mm phosphate buffer (pH 7.0). Solution B was a mixture of 10 mm MBTH (3 mL) and hemoglobin (5 mg/mL, 3 mL) in 50 ... | Chem Biol Drug Des 88: 460-9 (2016) Article DOI: 10.1111/cbdd.12779 BindingDB Entry DOI: 10.7270/Q2TT4PSF | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Seed linoleate 13S-lipoxygenase-1 (Glycine max (soybean)) | BDBM192758 (1-Allyl-2,4-dimethoxybenzene (4) | 1-Allyl-2,4-dim...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.03E+5 | n/a | n/a | n/a | n/a | 7.0 | 25 |
Ferdowsi University of Mashhad | Assay Description Solution A was 50 mm DMAB in an 100 mm phosphate buffer (pH 7.0). Solution B was a mixture of 10 mm MBTH (3 mL) and hemoglobin (5 mg/mL, 3 mL) in 50 ... | Chem Biol Drug Des 88: 460-9 (2016) Article DOI: 10.1111/cbdd.12779 BindingDB Entry DOI: 10.7270/Q2TT4PSF | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Seed linoleate 13S-lipoxygenase-1 (Glycine max (soybean)) | BDBM192760 (2-Allyl-1,3-dimethoxybenzene (6)) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.32E+4 | n/a | n/a | n/a | n/a | 7.0 | 25 |
Ferdowsi University of Mashhad | Assay Description Solution A was 50 mm DMAB in an 100 mm phosphate buffer (pH 7.0). Solution B was a mixture of 10 mm MBTH (3 mL) and hemoglobin (5 mg/mL, 3 mL) in 50 ... | Chem Biol Drug Des 88: 460-9 (2016) Article DOI: 10.1111/cbdd.12779 BindingDB Entry DOI: 10.7270/Q2TT4PSF | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Seed linoleate 13S-lipoxygenase-1 (Glycine max (soybean)) | BDBM192761 (2-Allyl-1,3,5-trimethoxybenzene (7)) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.32E+4 | n/a | n/a | n/a | n/a | 7.0 | 25 |
Ferdowsi University of Mashhad | Assay Description Solution A was 50 mm DMAB in an 100 mm phosphate buffer (pH 7.0). Solution B was a mixture of 10 mm MBTH (3 mL) and hemoglobin (5 mg/mL, 3 mL) in 50 ... | Chem Biol Drug Des 88: 460-9 (2016) Article DOI: 10.1111/cbdd.12779 BindingDB Entry DOI: 10.7270/Q2TT4PSF | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Seed linoleate 13S-lipoxygenase-1 (Glycine max (soybean)) | BDBM192762 (2-Allyl-1,3-dimethoxy-5-methylbenzene (8)) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.05E+4 | n/a | n/a | n/a | n/a | 7.0 | 25 |
Ferdowsi University of Mashhad | Assay Description Solution A was 50 mm DMAB in an 100 mm phosphate buffer (pH 7.0). Solution B was a mixture of 10 mm MBTH (3 mL) and hemoglobin (5 mg/mL, 3 mL) in 50 ... | Chem Biol Drug Des 88: 460-9 (2016) Article DOI: 10.1111/cbdd.12779 BindingDB Entry DOI: 10.7270/Q2TT4PSF | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Seed linoleate 13S-lipoxygenase-1 (Glycine max (soybean)) | BDBM192763 (1,3-Dimethoxy-5-methyl-2-(3-methylbut-2-en-1-yl)be...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.60E+3 | n/a | n/a | n/a | n/a | 7.0 | 25 |
Ferdowsi University of Mashhad | Assay Description Solution A was 50 mm DMAB in an 100 mm phosphate buffer (pH 7.0). Solution B was a mixture of 10 mm MBTH (3 mL) and hemoglobin (5 mg/mL, 3 mL) in 50 ... | Chem Biol Drug Des 88: 460-9 (2016) Article DOI: 10.1111/cbdd.12779 BindingDB Entry DOI: 10.7270/Q2TT4PSF | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Seed linoleate 13S-lipoxygenase-1 (Glycine max (soybean)) | BDBM192764 ((E)-2-(3,7-Dimethylocta-2,6-dien-1-yl)-1,3-dimetho...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.30E+3 | n/a | n/a | n/a | n/a | 7.0 | 25 |
Ferdowsi University of Mashhad | Assay Description Solution A was 50 mm DMAB in an 100 mm phosphate buffer (pH 7.0). Solution B was a mixture of 10 mm MBTH (3 mL) and hemoglobin (5 mg/mL, 3 mL) in 50 ... | Chem Biol Drug Des 88: 460-9 (2016) Article DOI: 10.1111/cbdd.12779 BindingDB Entry DOI: 10.7270/Q2TT4PSF | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Seed linoleate 13S-lipoxygenase-1 (Glycine max (soybean)) | BDBM192765 (1,3-Dimethoxy-5-methyl-2-((2E,6E)-3,7,11-trimethyl...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 520 | n/a | n/a | n/a | n/a | 7.0 | 25 |
Ferdowsi University of Mashhad | Assay Description Solution A was 50 mm DMAB in an 100 mm phosphate buffer (pH 7.0). Solution B was a mixture of 10 mm MBTH (3 mL) and hemoglobin (5 mg/mL, 3 mL) in 50 ... | Chem Biol Drug Des 88: 460-9 (2016) Article DOI: 10.1111/cbdd.12779 BindingDB Entry DOI: 10.7270/Q2TT4PSF | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Seed linoleate 13S-lipoxygenase-1 (Glycine max (soybean)) | BDBM192766 (4-MMPB) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.26E+4 | n/a | n/a | n/a | n/a | 7.0 | 25 |
Ferdowsi University of Mashhad | Assay Description Solution A was 50 mm DMAB in an 100 mm phosphate buffer (pH 7.0). Solution B was a mixture of 10 mm MBTH (3 mL) and hemoglobin (5 mg/mL, 3 mL) in 50 ... | Chem Biol Drug Des 88: 460-9 (2016) Article DOI: 10.1111/cbdd.12779 BindingDB Entry DOI: 10.7270/Q2TT4PSF | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Lipoxygenase (Glycine max (Soybean)) | BDBM111805 (2,6-Bis[4-(methylaminoethanol)benzylidine] cyclohe...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.24E+4 | n/a | n/a | n/a | n/a | 7.0 | 25 |
Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz, 50300, Kuala Lumpur, Malaysia | Assay Description The assay was progressed in 96-well microliter plates containing substrate, soybean LOX enzyme, and respective test substance at room temperature in ... | Chem Biol Drug Des 83: 670-81 (2014) Article DOI: 10.1111/cbdd.12280 BindingDB Entry DOI: 10.7270/Q26H4G2V | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Lipoxygenase (Glycine max (Soybean)) | BDBM111807 (2,6-Bis(2,3-dimethoxybenzylidene)cyclohexanone (3)) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.78E+4 | n/a | n/a | n/a | n/a | 7.0 | 25 |
Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz, 50300, Kuala Lumpur, Malaysia | Assay Description The assay was progressed in 96-well microliter plates containing substrate, soybean LOX enzyme, and respective test substance at room temperature in ... | Chem Biol Drug Des 83: 670-81 (2014) Article DOI: 10.1111/cbdd.12280 BindingDB Entry DOI: 10.7270/Q26H4G2V | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Lipoxygenase (Glycine max (Soybean)) | BDBM111809 (2,6-Bis[2-methyl-4(N-ethyl-N-ethylacetonitrile) an...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.00E+4 | n/a | n/a | n/a | n/a | 7.0 | 25 |
Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz, 50300, Kuala Lumpur, Malaysia | Assay Description The assay was progressed in 96-well microliter plates containing substrate, soybean LOX enzyme, and respective test substance at room temperature in ... | Chem Biol Drug Des 83: 670-81 (2014) Article DOI: 10.1111/cbdd.12280 BindingDB Entry DOI: 10.7270/Q26H4G2V | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Lipoxygenase (Glycine max (Soybean)) | BDBM111810 ((1Z,4Z)-1,5-Bis [4-(methylaminoethanol)phenyl]- 1,...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5.64E+4 | n/a | n/a | n/a | n/a | 7.0 | 25 |
Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz, 50300, Kuala Lumpur, Malaysia | Assay Description The assay was progressed in 96-well microliter plates containing substrate, soybean LOX enzyme, and respective test substance at room temperature in ... | Chem Biol Drug Des 83: 670-81 (2014) Article DOI: 10.1111/cbdd.12280 BindingDB Entry DOI: 10.7270/Q26H4G2V | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Lipoxygenase (Glycine max (Soybean)) | BDBM111811 ((1Z,4Z)–1-5-Bis[2,3(dimethoxy)phenyl]-1,4- pe...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.29E+4 | n/a | n/a | n/a | n/a | 7.0 | 25 |
Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz, 50300, Kuala Lumpur, Malaysia | Assay Description The assay was progressed in 96-well microliter plates containing substrate, soybean LOX enzyme, and respective test substance at room temperature in ... | Chem Biol Drug Des 83: 670-81 (2014) Article DOI: 10.1111/cbdd.12280 BindingDB Entry DOI: 10.7270/Q26H4G2V | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Lipoxygenase (Glycine max (Soybean)) | BDBM111812 ((1E,4E)‐1,5‐bis[4‐(diethylamino)...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9.51E+4 | n/a | n/a | n/a | n/a | 7.0 | 25 |
Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz, 50300, Kuala Lumpur, Malaysia | Assay Description The assay was progressed in 96-well microliter plates containing substrate, soybean LOX enzyme, and respective test substance at room temperature in ... | Chem Biol Drug Des 83: 670-81 (2014) Article DOI: 10.1111/cbdd.12280 BindingDB Entry DOI: 10.7270/Q26H4G2V | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Lipoxygenase (Glycine max (Soybean)) | BDBM111813 ((1E,4E)-1,5-Bis[2-methyl-4(N-ethyl-Nethylacetonitr...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.11E+4 | n/a | n/a | n/a | n/a | 7.0 | 25 |
Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz, 50300, Kuala Lumpur, Malaysia | Assay Description The assay was progressed in 96-well microliter plates containing substrate, soybean LOX enzyme, and respective test substance at room temperature in ... | Chem Biol Drug Des 83: 670-81 (2014) Article DOI: 10.1111/cbdd.12280 BindingDB Entry DOI: 10.7270/Q26H4G2V | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Lipoxygenase (Glycine max (Soybean)) | BDBM111814 (2,5-Bis[4-(methylaminoethanol)benzylidene] cyclope...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.95E+4 | n/a | n/a | n/a | n/a | 7.0 | 25 |
Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz, 50300, Kuala Lumpur, Malaysia | Assay Description The assay was progressed in 96-well microliter plates containing substrate, soybean LOX enzyme, and respective test substance at room temperature in ... | Chem Biol Drug Des 83: 670-81 (2014) Article DOI: 10.1111/cbdd.12280 BindingDB Entry DOI: 10.7270/Q26H4G2V | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Lipoxygenase (Glycine max (Soybean)) | BDBM111816 ((2E,5E)‐2,5‐bis[(2,3‐ dimethoxyp...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.38E+4 | n/a | n/a | n/a | n/a | 7.0 | 25 |
Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz, 50300, Kuala Lumpur, Malaysia | Assay Description The assay was progressed in 96-well microliter plates containing substrate, soybean LOX enzyme, and respective test substance at room temperature in ... | Chem Biol Drug Des 83: 670-81 (2014) Article DOI: 10.1111/cbdd.12280 BindingDB Entry DOI: 10.7270/Q26H4G2V | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Lipoxygenase (Glycine max (Soybean)) | BDBM111817 (2,5-Bis(4-diethylaminobenzylidene)cyclopentanone (...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.68E+4 | n/a | n/a | n/a | n/a | 7.0 | 25 |
Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz, 50300, Kuala Lumpur, Malaysia | Assay Description The assay was progressed in 96-well microliter plates containing substrate, soybean LOX enzyme, and respective test substance at room temperature in ... | Chem Biol Drug Des 83: 670-81 (2014) Article DOI: 10.1111/cbdd.12280 BindingDB Entry DOI: 10.7270/Q26H4G2V | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Lipoxygenase (Glycine max (Soybean)) | BDBM29532 ((1E,6E)-1,7-bis(3-methoxy-4-oxidanyl-phenyl)hepta-...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 5.78E+4 | n/a | n/a | n/a | n/a | 7.0 | 25 |
Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz, 50300, Kuala Lumpur, Malaysia | Assay Description The assay was progressed in 96-well microliter plates containing substrate, soybean LOX enzyme, and respective test substance at room temperature in ... | Chem Biol Drug Des 83: 670-81 (2014) Article DOI: 10.1111/cbdd.12280 BindingDB Entry DOI: 10.7270/Q26H4G2V | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Lipoxygenase (Glycine max (Soybean)) | BDBM32020 (4-[4-(3,4-dihydroxyphenyl)-2,3-dimethyl-butyl]pyro...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 9.23E+3 | n/a | n/a | n/a | n/a | 7.0 | 25 |
Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz, 50300, Kuala Lumpur, Malaysia | Assay Description The assay was progressed in 96-well microliter plates containing substrate, soybean LOX enzyme, and respective test substance at room temperature in ... | Chem Biol Drug Des 83: 670-81 (2014) Article DOI: 10.1111/cbdd.12280 BindingDB Entry DOI: 10.7270/Q26H4G2V | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Seed linoleate 13S-lipoxygenase-1 (Glycine max (soybean)) | BDBM152742 (3,5-bis((5-bromo-6-methyl-2-morpholinopyrimidin-4-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >5.00E+5 | n/a | n/a | n/a | n/a | 7.0 | 25 |
Ferdowsi University of Mashhad | Assay Description Linoleic acid and two assay solutions (A and B) were prepared in advance. Solution A was 50 mM 3-(dimethylamino)benzoic acid (DMAB) in a 100 mM phosp... | Chem Biol Drug Des 85: 216-24 (2015) Article DOI: 10.1111/cbdd.12375 BindingDB Entry DOI: 10.7270/Q2ST7NK5 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Seed linoleate 13S-lipoxygenase-1 (Glycine max (soybean)) | BDBM152743 (3,5-bis((5-bromo-6-methyl-2-(piperidin-1-yl)pyrimi...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >5.00E+5 | n/a | n/a | n/a | n/a | 7.0 | 25 |
Ferdowsi University of Mashhad | Assay Description Linoleic acid and two assay solutions (A and B) were prepared in advance. Solution A was 50 mM 3-(dimethylamino)benzoic acid (DMAB) in a 100 mM phosp... | Chem Biol Drug Des 85: 216-24 (2015) Article DOI: 10.1111/cbdd.12375 BindingDB Entry DOI: 10.7270/Q2ST7NK5 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Seed linoleate 13S-lipoxygenase-1 (Glycine max (soybean)) | BDBM152744 (3,5-bis((5-bromo-6-methyl-2-(4-methylpiperidin-1-y...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >5.00E+5 | n/a | n/a | n/a | n/a | 7.0 | 25 |
Ferdowsi University of Mashhad | Assay Description Linoleic acid and two assay solutions (A and B) were prepared in advance. Solution A was 50 mM 3-(dimethylamino)benzoic acid (DMAB) in a 100 mM phosp... | Chem Biol Drug Des 85: 216-24 (2015) Article DOI: 10.1111/cbdd.12375 BindingDB Entry DOI: 10.7270/Q2ST7NK5 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Seed linoleate 13S-lipoxygenase-1 (Glycine max (soybean)) | BDBM152745 (3,5-bis((5-bromo-6-methyl-2-(4-methylpiperazin-1-y...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9.00E+3 | n/a | n/a | n/a | n/a | 7.0 | 25 |
Ferdowsi University of Mashhad | Assay Description Linoleic acid and two assay solutions (A and B) were prepared in advance. Solution A was 50 mM 3-(dimethylamino)benzoic acid (DMAB) in a 100 mM phosp... | Chem Biol Drug Des 85: 216-24 (2015) Article DOI: 10.1111/cbdd.12375 BindingDB Entry DOI: 10.7270/Q2ST7NK5 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Seed linoleate 13S-lipoxygenase-1 (Glycine max (soybean)) | BDBM152746 (3,5-bis((5-bromo-6-methyl-2-(4-phenylpiperazin-1-y...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >5.00E+5 | n/a | n/a | n/a | n/a | 7.0 | 25 |
Ferdowsi University of Mashhad | Assay Description Linoleic acid and two assay solutions (A and B) were prepared in advance. Solution A was 50 mM 3-(dimethylamino)benzoic acid (DMAB) in a 100 mM phosp... | Chem Biol Drug Des 85: 216-24 (2015) Article DOI: 10.1111/cbdd.12375 BindingDB Entry DOI: 10.7270/Q2ST7NK5 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Seed linoleate 13S-lipoxygenase-1 (Glycine max (soybean)) | BDBM152747 (3,5-bis((5-bromo-6-methyl-2-(4-ethylpiperazin-1-yl...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.20E+4 | n/a | n/a | n/a | n/a | 7.0 | 25 |
Ferdowsi University of Mashhad | Assay Description Linoleic acid and two assay solutions (A and B) were prepared in advance. Solution A was 50 mM 3-(dimethylamino)benzoic acid (DMAB) in a 100 mM phosp... | Chem Biol Drug Des 85: 216-24 (2015) Article DOI: 10.1111/cbdd.12375 BindingDB Entry DOI: 10.7270/Q2ST7NK5 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Seed linoleate 13S-lipoxygenase-1 (Glycine max (soybean)) | BDBM152748 (3,5-bis((5-bromo-6-methyl-2-(pyrrolidin-1-yl)pyrim...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >5.00E+5 | n/a | n/a | n/a | n/a | 7.0 | 25 |
Ferdowsi University of Mashhad | Assay Description Linoleic acid and two assay solutions (A and B) were prepared in advance. Solution A was 50 mM 3-(dimethylamino)benzoic acid (DMAB) in a 100 mM phosp... | Chem Biol Drug Des 85: 216-24 (2015) Article DOI: 10.1111/cbdd.12375 BindingDB Entry DOI: 10.7270/Q2ST7NK5 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Seed linoleate 13S-lipoxygenase-1 (Glycine max (soybean)) | BDBM152749 (4-(5-bromo-4-methyl-6-((6-methyl-8-morpholino-5H-p...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >5.00E+5 | n/a | n/a | n/a | n/a | 7.0 | 25 |
Ferdowsi University of Mashhad | Assay Description Linoleic acid and two assay solutions (A and B) were prepared in advance. Solution A was 50 mM 3-(dimethylamino)benzoic acid (DMAB) in a 100 mM phosp... | Chem Biol Drug Des 85: 216-24 (2015) Article DOI: 10.1111/cbdd.12375 BindingDB Entry DOI: 10.7270/Q2ST7NK5 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Seed linoleate 13S-lipoxygenase-1 (Glycine max (soybean)) | BDBM152750 (3-((5-bromo-6-methyl-2-(piperidin-1-yl)pyrimidin-4...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >5.00E+5 | n/a | n/a | n/a | n/a | 7.0 | 25 |
Ferdowsi University of Mashhad | Assay Description Linoleic acid and two assay solutions (A and B) were prepared in advance. Solution A was 50 mM 3-(dimethylamino)benzoic acid (DMAB) in a 100 mM phosp... | Chem Biol Drug Des 85: 216-24 (2015) Article DOI: 10.1111/cbdd.12375 BindingDB Entry DOI: 10.7270/Q2ST7NK5 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Seed linoleate 13S-lipoxygenase-1 (Glycine max (soybean)) | BDBM152751 (3-((5-bromo-6-methyl-2-(4-methylpiperidin-1-yl)pyr...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >5.00E+5 | n/a | n/a | n/a | n/a | 7.0 | 25 |
Ferdowsi University of Mashhad | Assay Description Linoleic acid and two assay solutions (A and B) were prepared in advance. Solution A was 50 mM 3-(dimethylamino)benzoic acid (DMAB) in a 100 mM phosp... | Chem Biol Drug Des 85: 216-24 (2015) Article DOI: 10.1111/cbdd.12375 BindingDB Entry DOI: 10.7270/Q2ST7NK5 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Seed linoleate 13S-lipoxygenase-1 (Glycine max (soybean)) | BDBM152752 (3-((5-bromo-6-methyl-2-(4-methylpiperazin-1-yl)pyr...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >5.00E+5 | n/a | n/a | n/a | n/a | 7.0 | 25 |
Ferdowsi University of Mashhad | Assay Description Linoleic acid and two assay solutions (A and B) were prepared in advance. Solution A was 50 mM 3-(dimethylamino)benzoic acid (DMAB) in a 100 mM phosp... | Chem Biol Drug Des 85: 216-24 (2015) Article DOI: 10.1111/cbdd.12375 BindingDB Entry DOI: 10.7270/Q2ST7NK5 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Seed linoleate 13S-lipoxygenase-1 (Glycine max (soybean)) | BDBM22340 ((5E)-5-[(3-nitrophenyl)methylidene]-2-(1,3-thiazol...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.91E+4 | n/a | n/a | n/a | n/a | 7.4 | 28 |
Aristotle University | Assay Description The tested compounds were added to the reaction mixture with soybean lipoxygenase. Enzyme reaction was initiated by the addition of sodium linoleate ... | J Med Chem 51: 1601-9 (2008) Article DOI: 10.1021/jm701496h BindingDB Entry DOI: 10.7270/Q2JM27XJ | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Seed linoleate 13S-lipoxygenase-1 (Glycine max (soybean)) | BDBM22339 ((5E)-5-[(4-nitrophenyl)methylidene]-2-(1,3-thiazol...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.51E+5 | n/a | n/a | n/a | n/a | 7.4 | 28 |
Aristotle University | Assay Description The tested compounds were added to the reaction mixture with soybean lipoxygenase. Enzyme reaction was initiated by the addition of sodium linoleate ... | J Med Chem 51: 1601-9 (2008) Article DOI: 10.1021/jm701496h BindingDB Entry DOI: 10.7270/Q2JM27XJ | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Seed linoleate 13S-lipoxygenase-1 (Glycine max (soybean)) | BDBM22338 ((5E)-5-[(4-methoxyphenyl)methylidene]-2-(1,3-thiaz...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.22E+5 | n/a | n/a | n/a | n/a | 7.4 | 28 |
Aristotle University | Assay Description The tested compounds were added to the reaction mixture with soybean lipoxygenase. Enzyme reaction was initiated by the addition of sodium linoleate ... | J Med Chem 51: 1601-9 (2008) Article DOI: 10.1021/jm701496h BindingDB Entry DOI: 10.7270/Q2JM27XJ | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Seed linoleate 13S-lipoxygenase-1 (Glycine max (soybean)) | BDBM22337 ((5E)-5-[(4-hydroxy-3-methoxyphenyl)methylidene]-2-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9.95E+4 | n/a | n/a | n/a | n/a | 7.4 | 28 |
Aristotle University | Assay Description The tested compounds were added to the reaction mixture with soybean lipoxygenase. Enzyme reaction was initiated by the addition of sodium linoleate ... | J Med Chem 51: 1601-9 (2008) Article DOI: 10.1021/jm701496h BindingDB Entry DOI: 10.7270/Q2JM27XJ | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Seed linoleate 13S-lipoxygenase-1 (Glycine max (soybean)) | BDBM22341 ((5E)-5-[(4-chlorophenyl)methylidene]-2-(1,3-thiazo...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.20E+5 | n/a | n/a | n/a | n/a | 7.4 | 28 |
Aristotle University | Assay Description The tested compounds were added to the reaction mixture with soybean lipoxygenase. Enzyme reaction was initiated by the addition of sodium linoleate ... | J Med Chem 51: 1601-9 (2008) Article DOI: 10.1021/jm701496h BindingDB Entry DOI: 10.7270/Q2JM27XJ | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Seed linoleate 13S-lipoxygenase-1 (Glycine max (soybean)) | BDBM22342 ((5E)-5-[(3-chlorophenyl)methylidene]-2-(1,3-thiazo...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.26E+5 | n/a | n/a | n/a | n/a | 7.4 | 28 |
Aristotle University | Assay Description The tested compounds were added to the reaction mixture with soybean lipoxygenase. Enzyme reaction was initiated by the addition of sodium linoleate ... | J Med Chem 51: 1601-9 (2008) Article DOI: 10.1021/jm701496h BindingDB Entry DOI: 10.7270/Q2JM27XJ | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Seed linoleate 13S-lipoxygenase-1 (Glycine max (soybean)) | BDBM22343 ((5E)-5-[(2-chlorophenyl)methylidene]-2-(1,3-thiazo...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.15E+5 | n/a | n/a | n/a | n/a | 7.4 | 28 |
Aristotle University | Assay Description The tested compounds were added to the reaction mixture with soybean lipoxygenase. Enzyme reaction was initiated by the addition of sodium linoleate ... | J Med Chem 51: 1601-9 (2008) Article DOI: 10.1021/jm701496h BindingDB Entry DOI: 10.7270/Q2JM27XJ | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Seed linoleate 13S-lipoxygenase-1 (Glycine max (soybean)) | BDBM22335 ((5E)-5-[(4-hydroxyphenyl)methylidene]-2-(1,3-thiaz...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.16E+5 | n/a | n/a | n/a | n/a | 7.4 | 28 |
Aristotle University | Assay Description The tested compounds were added to the reaction mixture with soybean lipoxygenase. Enzyme reaction was initiated by the addition of sodium linoleate ... | J Med Chem 51: 1601-9 (2008) Article DOI: 10.1021/jm701496h BindingDB Entry DOI: 10.7270/Q2JM27XJ | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Arachidonate 12-lipoxygenase, 12R-type (Homo sapiens (Human)) | BDBM86010 (Chalcone, 10) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | 5.76E+4 | -24.2 | n/a | n/a | n/a | n/a | n/a | 8.0 | 25 |
Quaid-i-Azam University | Assay Description In vitro lipoxygenase inhibition assay, lipoxygenase inhibiting activity was convenintly measured by slightly modifying the spectrometic method devel... | J Enzyme Inhib Med Chem 20: 41-7 (2005) Article DOI: 10.1080/14756360400015231 BindingDB Entry DOI: 10.7270/Q2FX781C | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Arachidonate 12-lipoxygenase, 12R-type (Homo sapiens (Human)) | BDBM86012 (Chalcone, 11) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | 7.17E+4 | -23.7 | n/a | n/a | n/a | n/a | n/a | 8.0 | 25 |
Quaid-i-Azam University | Assay Description In vitro lipoxygenase inhibition assay, lipoxygenase inhibiting activity was convenintly measured by slightly modifying the spectrometic method devel... | J Enzyme Inhib Med Chem 20: 41-7 (2005) Article DOI: 10.1080/14756360400015231 BindingDB Entry DOI: 10.7270/Q2FX781C | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Seed linoleate 13S-lipoxygenase-1 (Glycine max (soybean)) | BDBM32020 (4-[4-(3,4-dihydroxyphenyl)-2,3-dimethyl-butyl]pyro...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 3.27E+4 | n/a | n/a | n/a | n/a | 8.0 | n/a |
CSIR - Indian Institute of Chemical Biology | Assay Description SLO inhibition was studied by spectrophotometric assay by measuring the change in the absorbance at 234 nm due to formation of hydroperoxylinoleic ac... | Bioorg Chem 71: 97-101 (2017) Article DOI: 10.1016/j.bioorg.2017.01.016 BindingDB Entry DOI: 10.7270/Q2F76BCD | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Seed linoleate 13S-lipoxygenase-1 (Glycine max (soybean)) | BDBM233017 (Conferin (1)) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5.52E+4 | n/a | n/a | n/a | n/a | 8.0 | 25 |
University of Karachi | Assay Description A mixture of test compound (10 μL; 1 mM) in MeOH, type-1B lipoxygenase (EC 1.13.11.12; from soyabean) (20 μL; 70 units) in 0.1 M aqueous ph... | J Enzyme Inhib Med Chem 25: 440-4 (2010) Article DOI: 10.1080/14756360903179484 BindingDB Entry DOI: 10.7270/Q2V986X3 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
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