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Patent code US8937070

Compile Data Set for Download or QSAR
Found 24 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tyrosine-protein kinase JAK3


(Homo sapiens (Human))		BDBM100350
PNG
(US10533001, Example 99 | US11414410, Example 99 | ...)
Show SMILES CS(=O)(=O)N1CCN(CC1)c1ccc(Nc2ncc(C(N)=O)c(NC3CC3)n2)cc1
Show InChI InChI=1S/C19H25N7O3S/c1-30(28,29)26-10-8-25(9-11-26)15-6-4-14(5-7-15)23-19-21-12-16(17(20)27)18(24-19)22-13-2-3-13/h4-7,12-13H,2-3,8-11H2,1H3,(H2,20,27)(H2,21,22,23,24)
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n/an/an/a 2.70n/an/an/an/an/a



Portola Pharmaceuticals, Inc.

US Patent


Assay Description
This assay is an ATP-site dependent competition binding assay in which human kinases of interest are fused to a proprietary tag (T7 bacteriophage). T...

US Patent US8937070 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22RV
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK3


(Homo sapiens (Human))		BDBM100350
PNG
(US10533001, Example 99 | US11414410, Example 99 | ...)
Show SMILES CS(=O)(=O)N1CCN(CC1)c1ccc(Nc2ncc(C(N)=O)c(NC3CC3)n2)cc1
Show InChI InChI=1S/C19H25N7O3S/c1-30(28,29)26-10-8-25(9-11-26)15-6-4-14(5-7-15)23-19-21-12-16(17(20)27)18(24-19)22-13-2-3-13/h4-7,12-13H,2-3,8-11H2,1H3,(H2,20,27)(H2,21,22,23,24)
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n/an/an/a 2.70n/an/an/an/an/a



Portola Pharmaceuticals, Inc.

US Patent


Assay Description
This assay is an ATP-site dependent competition binding assay in which human kinases of interest are fused to a proprietary tag (T7 bacteriophage). T...

US Patent US8937070 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22RV
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK3


(Homo sapiens (Human))		BDBM100348
PNG
(US10533001, Example Table 9a.1 | US11414410, Table...)
Show SMILES COCC(=O)N1CCN(CC1)c1ccc(Nc2ncc(C(N)=O)c(NC3CC3)n2)cc1
Show InChI InChI=1S/C21H27N7O3/c1-31-13-18(29)28-10-8-27(9-11-28)16-6-4-15(5-7-16)25-21-23-12-17(19(22)30)20(26-21)24-14-2-3-14/h4-7,12,14H,2-3,8-11,13H2,1H3,(H2,22,30)(H2,23,24,25,26)
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n/an/an/a 2.90n/an/an/an/an/a



Portola Pharmaceuticals, Inc.

US Patent


Assay Description
This assay is an ATP-site dependent competition binding assay in which human kinases of interest are fused to a proprietary tag (T7 bacteriophage). T...

US Patent US8937070 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22RV
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK3


(Homo sapiens (Human))		BDBM100348
PNG
(US10533001, Example Table 9a.1 | US11414410, Table...)
Show SMILES COCC(=O)N1CCN(CC1)c1ccc(Nc2ncc(C(N)=O)c(NC3CC3)n2)cc1
Show InChI InChI=1S/C21H27N7O3/c1-31-13-18(29)28-10-8-27(9-11-28)16-6-4-15(5-7-16)25-21-23-12-17(19(22)30)20(26-21)24-14-2-3-14/h4-7,12,14H,2-3,8-11,13H2,1H3,(H2,22,30)(H2,23,24,25,26)
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n/an/an/a 2.90n/an/an/an/an/a



Portola Pharmaceuticals, Inc.

US Patent


Assay Description
This assay is an ATP-site dependent competition binding assay in which human kinases of interest are fused to a proprietary tag (T7 bacteriophage). T...

US Patent US8937070 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22RV
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK3


(Homo sapiens (Human))		BDBM100349
PNG
(US10533001, Example Table 9a.2 | US11414410, Table...)
Show SMILES CNC(=O)[C@H]1CCCN(C1)c1ccc(Nc2ncc(C(N)=O)c(NC3CC3)n2)cc1 |r|
Show InChI InChI=1S/C21H27N7O2/c1-23-20(30)13-3-2-10-28(12-13)16-8-6-15(7-9-16)26-21-24-11-17(18(22)29)19(27-21)25-14-4-5-14/h6-9,11,13-14H,2-5,10,12H2,1H3,(H2,22,29)(H,23,30)(H2,24,25,26,27)/t13-/m0/s1
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n/an/an/a 3n/an/an/an/an/a



Portola Pharmaceuticals, Inc.

US Patent


Assay Description
This assay is an ATP-site dependent competition binding assay in which human kinases of interest are fused to a proprietary tag (T7 bacteriophage). T...

US Patent US8937070 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22RV
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK3


(Homo sapiens (Human))		BDBM100351
PNG
(US10533001, Example Table 9a.4 | US11414410, Table...)
Show SMILES NC(=O)[C@@H]1CCCN(C1)c1ccc(Nc2ncc(C(N)=O)c(NC3CC3)n2)cc1 |r|
Show InChI InChI=1S/C20H25N7O2/c21-17(28)12-2-1-9-27(11-12)15-7-5-14(6-8-15)25-20-23-10-16(18(22)29)19(26-20)24-13-3-4-13/h5-8,10,12-13H,1-4,9,11H2,(H2,21,28)(H2,22,29)(H2,23,24,25,26)/t12-/m1/s1
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n/an/an/a 4.10n/an/an/an/an/a



Portola Pharmaceuticals, Inc.

US Patent


Assay Description
This assay is an ATP-site dependent competition binding assay in which human kinases of interest are fused to a proprietary tag (T7 bacteriophage). T...

US Patent US8937070 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22RV
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK3


(Homo sapiens (Human))		BDBM100351
PNG
(US10533001, Example Table 9a.4 | US11414410, Table...)
Show SMILES NC(=O)[C@@H]1CCCN(C1)c1ccc(Nc2ncc(C(N)=O)c(NC3CC3)n2)cc1 |r|
Show InChI InChI=1S/C20H25N7O2/c21-17(28)12-2-1-9-27(11-12)15-7-5-14(6-8-15)25-20-23-10-16(18(22)29)19(26-20)24-13-3-4-13/h5-8,10,12-13H,1-4,9,11H2,(H2,21,28)(H2,22,29)(H2,23,24,25,26)/t12-/m1/s1
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n/an/an/a 4.10n/an/an/an/an/a



Portola Pharmaceuticals, Inc.

US Patent


Assay Description
This assay is an ATP-site dependent competition binding assay in which human kinases of interest are fused to a proprietary tag (T7 bacteriophage). T...

US Patent US8937070 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22RV
More data for this
Ligand-Target Pair
Tyrosine-protein kinase SYK


(Homo sapiens (Human))		BDBM100350
PNG
(US10533001, Example 99 | US11414410, Example 99 | ...)
Show SMILES CS(=O)(=O)N1CCN(CC1)c1ccc(Nc2ncc(C(N)=O)c(NC3CC3)n2)cc1
Show InChI InChI=1S/C19H25N7O3S/c1-30(28,29)26-10-8-25(9-11-26)15-6-4-14(5-7-15)23-19-21-12-16(17(20)27)18(24-19)22-13-2-3-13/h4-7,12-13H,2-3,8-11H2,1H3,(H2,20,27)(H2,21,22,23,24)
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n/an/an/a 4.5n/an/an/an/an/a



Portola Pharmaceuticals, Inc.

US Patent


Assay Description
This assay is an ATP-site dependent competition binding assay in which human kinases of interest are fused to a proprietary tag (T7 bacteriophage). T...

US Patent US8937070 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22RV
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))		BDBM100350
PNG
(US10533001, Example 99 | US11414410, Example 99 | ...)
Show SMILES CS(=O)(=O)N1CCN(CC1)c1ccc(Nc2ncc(C(N)=O)c(NC3CC3)n2)cc1
Show InChI InChI=1S/C19H25N7O3S/c1-30(28,29)26-10-8-25(9-11-26)15-6-4-14(5-7-15)23-19-21-12-16(17(20)27)18(24-19)22-13-2-3-13/h4-7,12-13H,2-3,8-11H2,1H3,(H2,20,27)(H2,21,22,23,24)
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n/an/an/a 4.70n/an/an/an/an/a



Portola Pharmaceuticals, Inc.

US Patent


Assay Description
This assay is an ATP-site dependent competition binding assay in which human kinases of interest are fused to a proprietary tag (T7 bacteriophage). T...

US Patent US8937070 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22RV
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))		BDBM100350
PNG
(US10533001, Example 99 | US11414410, Example 99 | ...)
Show SMILES CS(=O)(=O)N1CCN(CC1)c1ccc(Nc2ncc(C(N)=O)c(NC3CC3)n2)cc1
Show InChI InChI=1S/C19H25N7O3S/c1-30(28,29)26-10-8-25(9-11-26)15-6-4-14(5-7-15)23-19-21-12-16(17(20)27)18(24-19)22-13-2-3-13/h4-7,12-13H,2-3,8-11H2,1H3,(H2,20,27)(H2,21,22,23,24)
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n/an/an/a 4.70n/an/an/an/an/a



Portola Pharmaceuticals, Inc.

US Patent


Assay Description
This assay is an ATP-site dependent competition binding assay in which human kinases of interest are fused to a proprietary tag (T7 bacteriophage). T...

US Patent US8937070 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22RV
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK2


(Homo sapiens (Human))		BDBM100348
PNG
(US10533001, Example Table 9a.1 | US11414410, Table...)
Show SMILES COCC(=O)N1CCN(CC1)c1ccc(Nc2ncc(C(N)=O)c(NC3CC3)n2)cc1
Show InChI InChI=1S/C21H27N7O3/c1-31-13-18(29)28-10-8-27(9-11-28)16-6-4-15(5-7-16)25-21-23-12-17(19(22)30)20(26-21)24-14-2-3-14/h4-7,12,14H,2-3,8-11,13H2,1H3,(H2,22,30)(H2,23,24,25,26)
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n/an/an/a 5.10n/an/an/an/an/a



Portola Pharmaceuticals, Inc.

US Patent


Assay Description
This assay is an ATP-site dependent competition binding assay in which human kinases of interest are fused to a proprietary tag (T7 bacteriophage). T...

US Patent US8937070 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22RV
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK2


(Homo sapiens (Human))		BDBM100350
PNG
(US10533001, Example 99 | US11414410, Example 99 | ...)
Show SMILES CS(=O)(=O)N1CCN(CC1)c1ccc(Nc2ncc(C(N)=O)c(NC3CC3)n2)cc1
Show InChI InChI=1S/C19H25N7O3S/c1-30(28,29)26-10-8-25(9-11-26)15-6-4-14(5-7-15)23-19-21-12-16(17(20)27)18(24-19)22-13-2-3-13/h4-7,12-13H,2-3,8-11H2,1H3,(H2,20,27)(H2,21,22,23,24)
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n/an/an/a 5.10n/an/an/an/an/a



Portola Pharmaceuticals, Inc.

US Patent


Assay Description
This assay is an ATP-site dependent competition binding assay in which human kinases of interest are fused to a proprietary tag (T7 bacteriophage). T...

US Patent US8937070 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22RV
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))		BDBM100348
PNG
(US10533001, Example Table 9a.1 | US11414410, Table...)
Show SMILES COCC(=O)N1CCN(CC1)c1ccc(Nc2ncc(C(N)=O)c(NC3CC3)n2)cc1
Show InChI InChI=1S/C21H27N7O3/c1-31-13-18(29)28-10-8-27(9-11-28)16-6-4-15(5-7-16)25-21-23-12-17(19(22)30)20(26-21)24-14-2-3-14/h4-7,12,14H,2-3,8-11,13H2,1H3,(H2,22,30)(H2,23,24,25,26)
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n/an/an/a 6.70n/an/an/an/an/a



Portola Pharmaceuticals, Inc.

US Patent


Assay Description
This assay is an ATP-site dependent competition binding assay in which human kinases of interest are fused to a proprietary tag (T7 bacteriophage). T...

US Patent US8937070 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22RV
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))		BDBM100348
PNG
(US10533001, Example Table 9a.1 | US11414410, Table...)
Show SMILES COCC(=O)N1CCN(CC1)c1ccc(Nc2ncc(C(N)=O)c(NC3CC3)n2)cc1
Show InChI InChI=1S/C21H27N7O3/c1-31-13-18(29)28-10-8-27(9-11-28)16-6-4-15(5-7-16)25-21-23-12-17(19(22)30)20(26-21)24-14-2-3-14/h4-7,12,14H,2-3,8-11,13H2,1H3,(H2,22,30)(H2,23,24,25,26)
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n/an/an/a 6.70n/an/an/an/an/a



Portola Pharmaceuticals, Inc.

US Patent


Assay Description
This assay is an ATP-site dependent competition binding assay in which human kinases of interest are fused to a proprietary tag (T7 bacteriophage). T...

US Patent US8937070 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22RV
More data for this
Ligand-Target Pair
Tyrosine-protein kinase SYK


(Homo sapiens (Human))		BDBM100351
PNG
(US10533001, Example Table 9a.4 | US11414410, Table...)
Show SMILES NC(=O)[C@@H]1CCCN(C1)c1ccc(Nc2ncc(C(N)=O)c(NC3CC3)n2)cc1 |r|
Show InChI InChI=1S/C20H25N7O2/c21-17(28)12-2-1-9-27(11-12)15-7-5-14(6-8-15)25-20-23-10-16(18(22)29)19(26-20)24-13-3-4-13/h5-8,10,12-13H,1-4,9,11H2,(H2,21,28)(H2,22,29)(H2,23,24,25,26)/t12-/m1/s1
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n/an/an/a 9.40n/an/an/an/an/a



Portola Pharmaceuticals, Inc.

US Patent


Assay Description
This assay is an ATP-site dependent competition binding assay in which human kinases of interest are fused to a proprietary tag (T7 bacteriophage). T...

US Patent US8937070 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22RV
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK2


(Homo sapiens (Human))		BDBM100351
PNG
(US10533001, Example Table 9a.4 | US11414410, Table...)
Show SMILES NC(=O)[C@@H]1CCCN(C1)c1ccc(Nc2ncc(C(N)=O)c(NC3CC3)n2)cc1 |r|
Show InChI InChI=1S/C20H25N7O2/c21-17(28)12-2-1-9-27(11-12)15-7-5-14(6-8-15)25-20-23-10-16(18(22)29)19(26-20)24-13-3-4-13/h5-8,10,12-13H,1-4,9,11H2,(H2,21,28)(H2,22,29)(H2,23,24,25,26)/t12-/m1/s1
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n/an/an/a 10n/an/an/an/an/a



Portola Pharmaceuticals, Inc.

US Patent


Assay Description
This assay is an ATP-site dependent competition binding assay in which human kinases of interest are fused to a proprietary tag (T7 bacteriophage). T...

US Patent US8937070 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22RV
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))		BDBM100349
PNG
(US10533001, Example Table 9a.2 | US11414410, Table...)
Show SMILES CNC(=O)[C@H]1CCCN(C1)c1ccc(Nc2ncc(C(N)=O)c(NC3CC3)n2)cc1 |r|
Show InChI InChI=1S/C21H27N7O2/c1-23-20(30)13-3-2-10-28(12-13)16-8-6-15(7-9-16)26-21-24-11-17(18(22)29)19(27-21)25-14-4-5-14/h6-9,11,13-14H,2-5,10,12H2,1H3,(H2,22,29)(H,23,30)(H2,24,25,26,27)/t13-/m0/s1
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n/an/an/a 11n/an/an/an/an/a



Portola Pharmaceuticals, Inc.

US Patent


Assay Description
This assay is an ATP-site dependent competition binding assay in which human kinases of interest are fused to a proprietary tag (T7 bacteriophage). T...

US Patent US8937070 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22RV
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))		BDBM100351
PNG
(US10533001, Example Table 9a.4 | US11414410, Table...)
Show SMILES NC(=O)[C@@H]1CCCN(C1)c1ccc(Nc2ncc(C(N)=O)c(NC3CC3)n2)cc1 |r|
Show InChI InChI=1S/C20H25N7O2/c21-17(28)12-2-1-9-27(11-12)15-7-5-14(6-8-15)25-20-23-10-16(18(22)29)19(26-20)24-13-3-4-13/h5-8,10,12-13H,1-4,9,11H2,(H2,21,28)(H2,22,29)(H2,23,24,25,26)/t12-/m1/s1
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n/an/an/a 14n/an/an/an/an/a



Portola Pharmaceuticals, Inc.

US Patent


Assay Description
This assay is an ATP-site dependent competition binding assay in which human kinases of interest are fused to a proprietary tag (T7 bacteriophage). T...

US Patent US8937070 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22RV
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))		BDBM100351
PNG
(US10533001, Example Table 9a.4 | US11414410, Table...)
Show SMILES NC(=O)[C@@H]1CCCN(C1)c1ccc(Nc2ncc(C(N)=O)c(NC3CC3)n2)cc1 |r|
Show InChI InChI=1S/C20H25N7O2/c21-17(28)12-2-1-9-27(11-12)15-7-5-14(6-8-15)25-20-23-10-16(18(22)29)19(26-20)24-13-3-4-13/h5-8,10,12-13H,1-4,9,11H2,(H2,21,28)(H2,22,29)(H2,23,24,25,26)/t12-/m1/s1
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n/an/an/a 14n/an/an/an/an/a



Portola Pharmaceuticals, Inc.

US Patent


Assay Description
This assay is an ATP-site dependent competition binding assay in which human kinases of interest are fused to a proprietary tag (T7 bacteriophage). T...

US Patent US8937070 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22RV
More data for this
Ligand-Target Pair
Tyrosine-protein kinase SYK


(Homo sapiens (Human))		BDBM100348
PNG
(US10533001, Example Table 9a.1 | US11414410, Table...)
Show SMILES COCC(=O)N1CCN(CC1)c1ccc(Nc2ncc(C(N)=O)c(NC3CC3)n2)cc1
Show InChI InChI=1S/C21H27N7O3/c1-31-13-18(29)28-10-8-27(9-11-28)16-6-4-15(5-7-16)25-21-23-12-17(19(22)30)20(26-21)24-14-2-3-14/h4-7,12,14H,2-3,8-11,13H2,1H3,(H2,22,30)(H2,23,24,25,26)
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n/an/an/a 98n/an/an/an/an/a



Portola Pharmaceuticals, Inc.

US Patent


Assay Description
This assay is an ATP-site dependent competition binding assay in which human kinases of interest are fused to a proprietary tag (T7 bacteriophage). T...

US Patent US8937070 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22RV
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))		BDBM100350
PNG
(US10533001, Example 99 | US11414410, Example 99 | ...)
Show SMILES CS(=O)(=O)N1CCN(CC1)c1ccc(Nc2ncc(C(N)=O)c(NC3CC3)n2)cc1
Show InChI InChI=1S/C19H25N7O3S/c1-30(28,29)26-10-8-25(9-11-26)15-6-4-14(5-7-15)23-19-21-12-16(17(20)27)18(24-19)22-13-2-3-13/h4-7,12-13H,2-3,8-11H2,1H3,(H2,20,27)(H2,21,22,23,24)
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n/an/a 6.70n/an/an/an/an/an/a



Portola Pharmaceuticals, Inc.

US Patent


Assay Description
SYK tyrosine phosphorylation activity is measured using the LANCE Technology developed by Perkin Elmer Life and Analytical Sciences (Boston, Mass.). ...

US Patent US8937070 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22RV
More data for this
Ligand-Target Pair
Tyrosine-protein kinase SYK


(Homo sapiens (Human))		BDBM100350
PNG
(US10533001, Example 99 | US11414410, Example 99 | ...)
Show SMILES CS(=O)(=O)N1CCN(CC1)c1ccc(Nc2ncc(C(N)=O)c(NC3CC3)n2)cc1
Show InChI InChI=1S/C19H25N7O3S/c1-30(28,29)26-10-8-25(9-11-26)15-6-4-14(5-7-15)23-19-21-12-16(17(20)27)18(24-19)22-13-2-3-13/h4-7,12-13H,2-3,8-11H2,1H3,(H2,20,27)(H2,21,22,23,24)
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n/an/a 15n/an/an/an/an/an/a



Portola Pharmaceuticals, Inc.

US Patent


Assay Description
SYK tyrosine phosphorylation activity is measured using the LANCE Technology developed by Perkin Elmer Life and Analytical Sciences (Boston, Mass.). ...

US Patent US8937070 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22RV
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK3


(Homo sapiens (Human))		BDBM100350
PNG
(US10533001, Example 99 | US11414410, Example 99 | ...)
Show SMILES CS(=O)(=O)N1CCN(CC1)c1ccc(Nc2ncc(C(N)=O)c(NC3CC3)n2)cc1
Show InChI InChI=1S/C19H25N7O3S/c1-30(28,29)26-10-8-25(9-11-26)15-6-4-14(5-7-15)23-19-21-12-16(17(20)27)18(24-19)22-13-2-3-13/h4-7,12-13H,2-3,8-11H2,1H3,(H2,20,27)(H2,21,22,23,24)
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n/an/a 0.800n/an/an/an/an/an/a



Portola Pharmaceuticals, Inc.

US Patent


Assay Description
SYK tyrosine phosphorylation activity is measured using the LANCE Technology developed by Perkin Elmer Life and Analytical Sciences (Boston, Mass.). ...

US Patent US8937070 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22RV
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK2


(Homo sapiens (Human))		BDBM100350
PNG
(US10533001, Example 99 | US11414410, Example 99 | ...)
Show SMILES CS(=O)(=O)N1CCN(CC1)c1ccc(Nc2ncc(C(N)=O)c(NC3CC3)n2)cc1
Show InChI InChI=1S/C19H25N7O3S/c1-30(28,29)26-10-8-25(9-11-26)15-6-4-14(5-7-15)23-19-21-12-16(17(20)27)18(24-19)22-13-2-3-13/h4-7,12-13H,2-3,8-11H2,1H3,(H2,20,27)(H2,21,22,23,24)
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n/an/a 3.20n/an/an/an/an/an/a



Portola Pharmaceuticals, Inc.

US Patent


Assay Description
SYK tyrosine phosphorylation activity is measured using the LANCE Technology developed by Perkin Elmer Life and Analytical Sciences (Boston, Mass.). ...

US Patent US8937070 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22RV
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%