Affinity Data by PubMed id=14711305

PubMed code 14711305

Found 26 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50082556 ((S)-2,2-Dimethyl-4-[4-(pyridin-4-yloxy)-benzenesul...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	0.0500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens Curated by ChEMBL					Assay Description Inhibition of Matrix metalloprotease-2				J Med Chem 47: 325-36 (2004) Article DOI: 10.1021/jm0308491 BindingDB Entry DOI: 10.7270/Q27080V1
University of Athens Curated by ChEMBL					More data for this Ligand-Target Pair
Neutrophil collagenase (Homo sapiens (Human))	BDBM50138684 ((1-Benzyloxycarbonylamino-2-phenyl-ethyl)-{2-[1-ca...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens Curated by ChEMBL					Assay Description Inhibition of matrix metalloprotease-8				J Med Chem 47: 325-36 (2004) Article DOI: 10.1021/jm0308491 BindingDB Entry DOI: 10.7270/Q27080V1
University of Athens Curated by ChEMBL					More data for this Ligand-Target Pair
Stromelysin-3 (Mus musculus)	BDBM50138684 ((1-Benzyloxycarbonylamino-2-phenyl-ethyl)-{2-[1-ca...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens Curated by ChEMBL					Assay Description Inhibition of Matrix metalloprotease-11				J Med Chem 47: 325-36 (2004) Article DOI: 10.1021/jm0308491 BindingDB Entry DOI: 10.7270/Q27080V1
University of Athens Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50138684 ((1-Benzyloxycarbonylamino-2-phenyl-ethyl)-{2-[1-ca...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens Curated by ChEMBL					Assay Description Inhibition of Matrix metalloprotease-9				J Med Chem 47: 325-36 (2004) Article DOI: 10.1021/jm0308491 BindingDB Entry DOI: 10.7270/Q27080V1
University of Athens Curated by ChEMBL					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50138684 ((1-Benzyloxycarbonylamino-2-phenyl-ethyl)-{2-[1-ca...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens Curated by ChEMBL					Assay Description Inhibition of Matrix metalloprotease-2				J Med Chem 47: 325-36 (2004) Article DOI: 10.1021/jm0308491 BindingDB Entry DOI: 10.7270/Q27080V1
University of Athens Curated by ChEMBL					More data for this Ligand-Target Pair
Matrix metalloproteinase-14 (Homo sapiens (Human))	BDBM50138684 ((1-Benzyloxycarbonylamino-2-phenyl-ethyl)-{2-[1-ca...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	105	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens Curated by ChEMBL					Assay Description Inhibition of Matrix metalloprotease-14				J Med Chem 47: 325-36 (2004) Article DOI: 10.1021/jm0308491 BindingDB Entry DOI: 10.7270/Q27080V1
University of Athens Curated by ChEMBL					More data for this Ligand-Target Pair
Stromelysin-3 (Mus musculus)	BDBM50138683 ((1-Benzyloxycarbonylamino-2-phenyl-ethyl)-{3-(2-br...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens Curated by ChEMBL					Assay Description Inhibition of Matrix metalloprotease-11				J Med Chem 47: 325-36 (2004) Article DOI: 10.1021/jm0308491 BindingDB Entry DOI: 10.7270/Q27080V1
University of Athens Curated by ChEMBL					More data for this Ligand-Target Pair
Stromelysin-3 (Mus musculus)	BDBM50138685 ((1-Benzyloxycarbonylamino-2-phenyl-ethyl)-[2-[1-ca...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	230	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens Curated by ChEMBL					Assay Description Inhibition of Matrix metalloprotease-11				J Med Chem 47: 325-36 (2004) Article DOI: 10.1021/jm0308491 BindingDB Entry DOI: 10.7270/Q27080V1
University of Athens Curated by ChEMBL					More data for this Ligand-Target Pair
Stromelysin-3 (Mus musculus)	BDBM50138686 ((1-Benzyloxycarbonylamino-2-phenyl-ethyl)-[2-[1-ca...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	410	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens Curated by ChEMBL					Assay Description Inhibition of Matrix metalloprotease-11				J Med Chem 47: 325-36 (2004) Article DOI: 10.1021/jm0308491 BindingDB Entry DOI: 10.7270/Q27080V1
University of Athens Curated by ChEMBL					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM50138684 ((1-Benzyloxycarbonylamino-2-phenyl-ethyl)-{2-[1-ca...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens Curated by ChEMBL					Assay Description Inhibition of matrix metalloprotease-1				J Med Chem 47: 325-36 (2004) Article DOI: 10.1021/jm0308491 BindingDB Entry DOI: 10.7270/Q27080V1
University of Athens Curated by ChEMBL					More data for this Ligand-Target Pair
Matrilysin (Homo sapiens (Human))	BDBM50138684 ((1-Benzyloxycarbonylamino-2-phenyl-ethyl)-{2-[1-ca...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens Curated by ChEMBL					Assay Description Inhibition of Matrix metalloprotease-7				J Med Chem 47: 325-36 (2004) Article DOI: 10.1021/jm0308491 BindingDB Entry DOI: 10.7270/Q27080V1
University of Athens Curated by ChEMBL					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50138683 ((1-Benzyloxycarbonylamino-2-phenyl-ethyl)-{3-(2-br...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.91E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens Curated by ChEMBL					Assay Description Inhibition of Matrix metalloprotease-9				J Med Chem 47: 325-36 (2004) Article DOI: 10.1021/jm0308491 BindingDB Entry DOI: 10.7270/Q27080V1
University of Athens Curated by ChEMBL					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50138683 ((1-Benzyloxycarbonylamino-2-phenyl-ethyl)-{3-(2-br...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.65E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens Curated by ChEMBL					Assay Description Inhibition of Matrix metalloprotease-2				J Med Chem 47: 325-36 (2004) Article DOI: 10.1021/jm0308491 BindingDB Entry DOI: 10.7270/Q27080V1
University of Athens Curated by ChEMBL					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50138683 ((1-Benzyloxycarbonylamino-2-phenyl-ethyl)-{3-(2-br...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens Curated by ChEMBL					Assay Description Inhibition of matrix metalloprotease-13				J Med Chem 47: 325-36 (2004) Article DOI: 10.1021/jm0308491 BindingDB Entry DOI: 10.7270/Q27080V1
University of Athens Curated by ChEMBL					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50138685 ((1-Benzyloxycarbonylamino-2-phenyl-ethyl)-[2-[1-ca...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.57E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens Curated by ChEMBL					Assay Description Inhibition of matrix metalloprotease-13				J Med Chem 47: 325-36 (2004) Article DOI: 10.1021/jm0308491 BindingDB Entry DOI: 10.7270/Q27080V1
University of Athens Curated by ChEMBL					More data for this Ligand-Target Pair
Neutrophil collagenase (Homo sapiens (Human))	BDBM50138683 ((1-Benzyloxycarbonylamino-2-phenyl-ethyl)-{3-(2-br...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.84E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens Curated by ChEMBL					Assay Description Inhibition of matrix metalloprotease-8				J Med Chem 47: 325-36 (2004) Article DOI: 10.1021/jm0308491 BindingDB Entry DOI: 10.7270/Q27080V1
University of Athens Curated by ChEMBL					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50138685 ((1-Benzyloxycarbonylamino-2-phenyl-ethyl)-[2-[1-ca...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens Curated by ChEMBL					Assay Description Inhibition of Matrix metalloprotease-2				J Med Chem 47: 325-36 (2004) Article DOI: 10.1021/jm0308491 BindingDB Entry DOI: 10.7270/Q27080V1
University of Athens Curated by ChEMBL					More data for this Ligand-Target Pair
Matrix metalloproteinase-14 (Homo sapiens (Human))	BDBM50138686 ((1-Benzyloxycarbonylamino-2-phenyl-ethyl)-[2-[1-ca...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens Curated by ChEMBL					Assay Description Inhibition of Matrix metalloprotease-14				J Med Chem 47: 325-36 (2004) Article DOI: 10.1021/jm0308491 BindingDB Entry DOI: 10.7270/Q27080V1
University of Athens Curated by ChEMBL					More data for this Ligand-Target Pair
Matrix metalloproteinase-14 (Homo sapiens (Human))	BDBM50138683 ((1-Benzyloxycarbonylamino-2-phenyl-ethyl)-{3-(2-br...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.01E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens Curated by ChEMBL					Assay Description Inhibition of Matrix metalloprotease-14				J Med Chem 47: 325-36 (2004) Article DOI: 10.1021/jm0308491 BindingDB Entry DOI: 10.7270/Q27080V1
University of Athens Curated by ChEMBL					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50138685 ((1-Benzyloxycarbonylamino-2-phenyl-ethyl)-[2-[1-ca...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.56E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens Curated by ChEMBL					Assay Description Inhibition of Matrix metalloproteinase-9				J Med Chem 47: 325-36 (2004) Article DOI: 10.1021/jm0308491 BindingDB Entry DOI: 10.7270/Q27080V1
University of Athens Curated by ChEMBL					More data for this Ligand-Target Pair
Neutrophil collagenase (Homo sapiens (Human))	BDBM50138685 ((1-Benzyloxycarbonylamino-2-phenyl-ethyl)-[2-[1-ca...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.89E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens Curated by ChEMBL					Assay Description Inhibition of matrix metalloprotease-8				J Med Chem 47: 325-36 (2004) Article DOI: 10.1021/jm0308491 BindingDB Entry DOI: 10.7270/Q27080V1
University of Athens Curated by ChEMBL					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50138686 ((1-Benzyloxycarbonylamino-2-phenyl-ethyl)-[2-[1-ca...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.48E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens Curated by ChEMBL					Assay Description Inhibition of Matrix metalloprotease-9				J Med Chem 47: 325-36 (2004) Article DOI: 10.1021/jm0308491 BindingDB Entry DOI: 10.7270/Q27080V1
University of Athens Curated by ChEMBL					More data for this Ligand-Target Pair
Matrix metalloproteinase-14 (Homo sapiens (Human))	BDBM50138685 ((1-Benzyloxycarbonylamino-2-phenyl-ethyl)-[2-[1-ca...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.60E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens Curated by ChEMBL					Assay Description Inhibition of Matrix metalloprotease-14				J Med Chem 47: 325-36 (2004) Article DOI: 10.1021/jm0308491 BindingDB Entry DOI: 10.7270/Q27080V1
University of Athens Curated by ChEMBL					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50138686 ((1-Benzyloxycarbonylamino-2-phenyl-ethyl)-[2-[1-ca...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens Curated by ChEMBL					Assay Description Inhibition of Matrix metalloprotease-2				J Med Chem 47: 325-36 (2004) Article DOI: 10.1021/jm0308491 BindingDB Entry DOI: 10.7270/Q27080V1
University of Athens Curated by ChEMBL					More data for this Ligand-Target Pair
Neutrophil collagenase (Homo sapiens (Human))	BDBM50138686 ((1-Benzyloxycarbonylamino-2-phenyl-ethyl)-[2-[1-ca...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens Curated by ChEMBL					Assay Description Inhibition of matrix metalloprotease-8				J Med Chem 47: 325-36 (2004) Article DOI: 10.1021/jm0308491 BindingDB Entry DOI: 10.7270/Q27080V1
University of Athens Curated by ChEMBL					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50138686 ((1-Benzyloxycarbonylamino-2-phenyl-ethyl)-[2-[1-ca...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens Curated by ChEMBL					Assay Description Inhibition of matrix metalloprotease-13				J Med Chem 47: 325-36 (2004) Article DOI: 10.1021/jm0308491 BindingDB Entry DOI: 10.7270/Q27080V1
University of Athens Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%