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PubMed code 16061378

Compile data set for download or QSAR
Found 87 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM50171262
PNG
(1-Butyl-3-(2-dimethylamino-ethyl)-1H-indol-4-ol | ...)
Show SMILES CCCCn1cc(CCN(C)C)c2c(O)cccc12
Show InChI InChI=1S/C16H24N2O/c1-4-5-10-18-12-13(9-11-17(2)3)16-14(18)7-6-8-15(16)19/h6-8,12,19H,4-5,9-11H2,1-3H3
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 4.40n/an/an/an/an/an/an/an/a



Organix Inc.

Curated by ChEMBL


Assay Description
Inhibition constant against human 5-hydroxytryptamine 2C receptor [INI isoforms] using [3H]-mesulergine as radioligand with the compound (10 uM) diss...

Bioorg Med Chem Lett 15: 4555-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.104
BindingDB Entry DOI: 10.7270/Q2PZ58B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2B


(Homo sapiens (Human))		BDBM50171262
PNG
(1-Butyl-3-(2-dimethylamino-ethyl)-1H-indol-4-ol | ...)
Show SMILES CCCCn1cc(CCN(C)C)c2c(O)cccc12
Show InChI InChI=1S/C16H24N2O/c1-4-5-10-18-12-13(9-11-17(2)3)16-14(18)7-6-8-15(16)19/h6-8,12,19H,4-5,9-11H2,1-3H3
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 5.80n/an/an/an/an/an/an/an/a



Organix Inc.

Curated by ChEMBL


Assay Description
Inhibition constant against human 5-hydroxytryptamine 2B receptor using [3H]-LSD as radioligand with the compound (10 uM) dissolved in DMSO

Bioorg Med Chem Lett 15: 4555-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.104
BindingDB Entry DOI: 10.7270/Q2PZ58B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM50171261
PNG
(3-(2-Dimethylamino-ethyl)-1-methyl-1H-indol-4-ol |...)
Show SMILES CN(C)CCc1cn(C)c2cccc(O)c12
Show InChI InChI=1S/C13H18N2O/c1-14(2)8-7-10-9-15(3)11-5-4-6-12(16)13(10)11/h4-6,9,16H,7-8H2,1-3H3
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 7n/an/an/an/an/an/an/an/a



Organix Inc.

Curated by ChEMBL


Assay Description
Inhibition constant against human 5-hydroxytryptamine 2C receptor [INI isoforms] using [3H]-mesulergine as radioligand with the compound (10 uM) diss...

Bioorg Med Chem Lett 15: 4555-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.104
BindingDB Entry DOI: 10.7270/Q2PZ58B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2B


(Homo sapiens (Human))		BDBM50171264
PNG
(CHEMBL197646 | US11427604, Compound (I-43) | US115...)
Show SMILES CN(C)CCc1c[nH]c2cccc(F)c12
Show InChI InChI=1S/C12H15FN2/c1-15(2)7-6-9-8-14-11-5-3-4-10(13)12(9)11/h3-5,8,14H,6-7H2,1-2H3
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 8.39n/an/an/an/an/an/an/an/a



Organix Inc.

Curated by ChEMBL


Assay Description
Inhibition constant against human 5-hydroxytryptamine 2B receptor using [3H]-LSD as radioligand with the compound (10 uM) dissolved in DMSO

Bioorg Med Chem Lett 15: 4555-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.104
BindingDB Entry DOI: 10.7270/Q2PZ58B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM50171272
PNG
(3-Dimethylaminomethyl-1H-indol-4-ol | CHEMBL194588)
Show SMILES CN(C)Cc1c[nH]c2cccc(O)c12
Show InChI InChI=1S/C11H14N2O/c1-13(2)7-8-6-12-9-4-3-5-10(14)11(8)9/h3-6,12,14H,7H2,1-2H3
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 12.6n/an/an/an/an/an/an/an/a



Organix Inc.

Curated by ChEMBL


Assay Description
Inhibition constant against human 5-hydroxytryptamine 2C receptor [VGI isoforms] using [3H]-mesulergine as radioligand with the compound (10 uM) diss...

Bioorg Med Chem Lett 15: 4555-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.104
BindingDB Entry DOI: 10.7270/Q2PZ58B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM50171262
PNG
(1-Butyl-3-(2-dimethylamino-ethyl)-1H-indol-4-ol | ...)
Show SMILES CCCCn1cc(CCN(C)C)c2c(O)cccc12
Show InChI InChI=1S/C16H24N2O/c1-4-5-10-18-12-13(9-11-17(2)3)16-14(18)7-6-8-15(16)19/h6-8,12,19H,4-5,9-11H2,1-3H3
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 14n/an/an/an/an/an/an/an/a



Organix Inc.

Curated by ChEMBL


Assay Description
Inhibition constant against human 5-hydroxytryptamine 2C receptor [VGI isoforms] using [3H]-mesulergine as radioligand with the compound (10 uM) diss...

Bioorg Med Chem Lett 15: 4555-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.104
BindingDB Entry DOI: 10.7270/Q2PZ58B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Rattus norvegicus (Rat))		BDBM50171262
PNG
(1-Butyl-3-(2-dimethylamino-ethyl)-1H-indol-4-ol | ...)
Show SMILES CCCCn1cc(CCN(C)C)c2c(O)cccc12
Show InChI InChI=1S/C16H24N2O/c1-4-5-10-18-12-13(9-11-17(2)3)16-14(18)7-6-8-15(16)19/h6-8,12,19H,4-5,9-11H2,1-3H3
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 15.7n/an/an/an/an/an/an/an/a



Organix Inc.

Curated by ChEMBL


Assay Description
Inhibition constant against rat 5-hydroxytryptamine 2C receptor using [3H]-mesulergine as radioligand with the compound (10 uM) dissolved in DMSO

Bioorg Med Chem Lett 15: 4555-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.104
BindingDB Entry DOI: 10.7270/Q2PZ58B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM50171272
PNG
(3-Dimethylaminomethyl-1H-indol-4-ol | CHEMBL194588)
Show SMILES CN(C)Cc1c[nH]c2cccc(O)c12
Show InChI InChI=1S/C11H14N2O/c1-13(2)7-8-6-12-9-4-3-5-10(14)11(8)9/h3-6,12,14H,7H2,1-2H3
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 24n/an/an/an/an/an/an/an/a



Organix Inc.

Curated by ChEMBL


Assay Description
Inhibition constant against human 5-hydroxytryptamine 2C receptor [INI isoforms] using [3H]-mesulergine as radioligand with the compound (10 uM) diss...

Bioorg Med Chem Lett 15: 4555-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.104
BindingDB Entry DOI: 10.7270/Q2PZ58B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM50171261
PNG
(3-(2-Dimethylamino-ethyl)-1-methyl-1H-indol-4-ol |...)
Show SMILES CN(C)CCc1cn(C)c2cccc(O)c12
Show InChI InChI=1S/C13H18N2O/c1-14(2)8-7-10-9-15(3)11-5-4-6-12(16)13(10)11/h4-6,9,16H,7-8H2,1-3H3
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 33n/an/an/an/an/an/an/an/a



Organix Inc.

Curated by ChEMBL


Assay Description
Inhibition constant against human 5-hydroxytryptamine 2C receptor [VGI isoforms] using [3H]-mesulergine as radioligand with the compound (10 uM) diss...

Bioorg Med Chem Lett 15: 4555-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.104
BindingDB Entry DOI: 10.7270/Q2PZ58B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2B


(Homo sapiens (Human))		BDBM50171261
PNG
(3-(2-Dimethylamino-ethyl)-1-methyl-1H-indol-4-ol |...)
Show SMILES CN(C)CCc1cn(C)c2cccc(O)c12
Show InChI InChI=1S/C13H18N2O/c1-14(2)8-7-10-9-15(3)11-5-4-6-12(16)13(10)11/h4-6,9,16H,7-8H2,1-3H3
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 38n/an/an/an/an/an/an/an/a



Organix Inc.

Curated by ChEMBL


Assay Description
Inhibition constant against human 5-hydroxytryptamine 2B receptor using [3H]-LSD as radioligand with the compound (10 uM) dissolved in DMSO

Bioorg Med Chem Lett 15: 4555-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.104
BindingDB Entry DOI: 10.7270/Q2PZ58B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Rattus norvegicus (Rat))		BDBM50171261
PNG
(3-(2-Dimethylamino-ethyl)-1-methyl-1H-indol-4-ol |...)
Show SMILES CN(C)CCc1cn(C)c2cccc(O)c12
Show InChI InChI=1S/C13H18N2O/c1-14(2)8-7-10-9-15(3)11-5-4-6-12(16)13(10)11/h4-6,9,16H,7-8H2,1-3H3
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 48n/an/an/an/an/an/an/an/a



Organix Inc.

Curated by ChEMBL


Assay Description
Inhibition constant against rat 5-hydroxytryptamine 2C receptor using [3H]-mesulergine as radioligand with the compound (10 uM) dissolved in DMSO

Bioorg Med Chem Lett 15: 4555-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.104
BindingDB Entry DOI: 10.7270/Q2PZ58B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Rattus norvegicus (Rat))		BDBM50171272
PNG
(3-Dimethylaminomethyl-1H-indol-4-ol | CHEMBL194588)
Show SMILES CN(C)Cc1c[nH]c2cccc(O)c12
Show InChI InChI=1S/C11H14N2O/c1-13(2)7-8-6-12-9-4-3-5-10(14)11(8)9/h3-6,12,14H,7H2,1-2H3
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 49n/an/an/an/an/an/an/an/a



Organix Inc.

Curated by ChEMBL


Assay Description
Inhibition constant against rat 5-hydroxytryptamine 2C receptor using [3H]-mesulergine as radioligand with the compound (10 uM) dissolved in DMSO

Bioorg Med Chem Lett 15: 4555-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.104
BindingDB Entry DOI: 10.7270/Q2PZ58B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM50171263
PNG
(CHEMBL371753 | Phosphoric acid mono-[1-butyl-3-(2-...)
Show SMILES CCCCn1cc(CCN(C)C)c2c(OP(O)(O)=O)cccc12
Show InChI InChI=1S/C16H25N2O4P/c1-4-5-10-18-12-13(9-11-17(2)3)16-14(18)7-6-8-15(16)22-23(19,20)21/h6-8,12H,4-5,9-11H2,1-3H3,(H2,19,20,21)
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 73n/an/an/an/an/an/an/an/a



Organix Inc.

Curated by ChEMBL


Assay Description
Inhibition constant against human 5-hydroxytryptamine 2C receptor [INI isoforms] using [3H]-mesulergine as radioligand with the compound (10 uM) diss...

Bioorg Med Chem Lett 15: 4555-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.104
BindingDB Entry DOI: 10.7270/Q2PZ58B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM50171264
PNG
(CHEMBL197646 | US11427604, Compound (I-43) | US115...)
Show SMILES CN(C)CCc1c[nH]c2cccc(F)c12
Show InChI InChI=1S/C12H15FN2/c1-15(2)7-6-9-8-14-11-5-3-4-10(13)12(9)11/h3-5,8,14H,6-7H2,1-2H3
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 82n/an/an/an/an/an/an/an/a



Organix Inc.

Curated by ChEMBL


Assay Description
Inhibition constant against human 5-hydroxytryptamine 2C receptor [INI isoforms] using [3H]-mesulergine as radioligand with the compound (10 uM) diss...

Bioorg Med Chem Lett 15: 4555-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.104
BindingDB Entry DOI: 10.7270/Q2PZ58B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM50171270
PNG
(3-(3-Dimethylamino-propyl)-1H-indol-4-ol | CHEMBL1...)
Show SMILES CN(C)CCCc1c[nH]c2cccc(O)c12
Show InChI InChI=1S/C13H18N2O/c1-15(2)8-4-5-10-9-14-11-6-3-7-12(16)13(10)11/h3,6-7,9,14,16H,4-5,8H2,1-2H3
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 84n/an/an/an/an/an/an/an/a



Organix Inc.

Curated by ChEMBL


Assay Description
Inhibition constant against human 5-hydroxytryptamine 2C receptor [VGI isoforms] using [3H]-mesulergine as radioligand with the compound (10 uM) diss...

Bioorg Med Chem Lett 15: 4555-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.104
BindingDB Entry DOI: 10.7270/Q2PZ58B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM50171264
PNG
(CHEMBL197646 | US11427604, Compound (I-43) | US115...)
Show SMILES CN(C)CCc1c[nH]c2cccc(F)c12
Show InChI InChI=1S/C12H15FN2/c1-15(2)7-6-9-8-14-11-5-3-4-10(13)12(9)11/h3-5,8,14H,6-7H2,1-2H3
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 84n/an/an/an/an/an/an/an/a



Organix Inc.

Curated by ChEMBL


Assay Description
Inhibition constant against human 5-hydroxytryptamine 2C receptor [VGI isoforms] using [3H]-mesulergine as radioligand with the compound (10 uM) diss...

Bioorg Med Chem Lett 15: 4555-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.104
BindingDB Entry DOI: 10.7270/Q2PZ58B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM50171273
PNG
(3-Dimethylaminomethyl-1-methyl-1H-indol-4-ol | CHE...)
Show SMILES CN(C)Cc1cn(C)c2cccc(O)c12
Show InChI InChI=1S/C12H16N2O/c1-13(2)7-9-8-14(3)10-5-4-6-11(15)12(9)10/h4-6,8,15H,7H2,1-3H3
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 87n/an/an/an/an/an/an/an/a



Organix Inc.

Curated by ChEMBL


Assay Description
Inhibition constant against human 5-hydroxytryptamine 2C receptor [INI isoforms] using [3H]-mesulergine as radioligand with the compound (10 uM) diss...

Bioorg Med Chem Lett 15: 4555-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.104
BindingDB Entry DOI: 10.7270/Q2PZ58B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2B


(Homo sapiens (Human))		BDBM50171270
PNG
(3-(3-Dimethylamino-propyl)-1H-indol-4-ol | CHEMBL1...)
Show SMILES CN(C)CCCc1c[nH]c2cccc(O)c12
Show InChI InChI=1S/C13H18N2O/c1-15(2)8-4-5-10-9-14-11-6-3-7-12(16)13(10)11/h3,6-7,9,14,16H,4-5,8H2,1-2H3
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 98n/an/an/an/an/an/an/an/a



Organix Inc.

Curated by ChEMBL


Assay Description
Inhibition constant against human 5-hydroxytryptamine 2B receptor using [3H]-LSD as radioligand with the compound (10 uM) dissolved in DMSO

Bioorg Med Chem Lett 15: 4555-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.104
BindingDB Entry DOI: 10.7270/Q2PZ58B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM50171260
PNG
(3-[2-(4-Methyl-piperazin-1-yl)-ethyl]-1H-indol-4-o...)
Show SMILES CN1CCN(CCc2c[nH]c3cccc(O)c23)CC1
Show InChI InChI=1S/C15H21N3O/c1-17-7-9-18(10-8-17)6-5-12-11-16-13-3-2-4-14(19)15(12)13/h2-4,11,16,19H,5-10H2,1H3
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 103n/an/an/an/an/an/an/an/a



Organix Inc.

Curated by ChEMBL


Assay Description
Inhibition constant against human 5-hydroxytryptamine 2C receptor [INI isoforms] using [3H]-mesulergine as radioligand with the compound (10 uM) diss...

Bioorg Med Chem Lett 15: 4555-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.104
BindingDB Entry DOI: 10.7270/Q2PZ58B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2B


(Homo sapiens (Human))		BDBM50171260
PNG
(3-[2-(4-Methyl-piperazin-1-yl)-ethyl]-1H-indol-4-o...)
Show SMILES CN1CCN(CCc2c[nH]c3cccc(O)c23)CC1
Show InChI InChI=1S/C15H21N3O/c1-17-7-9-18(10-8-17)6-5-12-11-16-13-3-2-4-14(19)15(12)13/h2-4,11,16,19H,5-10H2,1H3
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 116n/an/an/an/an/an/an/an/a



Organix Inc.

Curated by ChEMBL


Assay Description
Inhibition constant against human 5-hydroxytryptamine 2B receptor using [3H]-LSD as radioligand with the compound (10 uM) dissolved in DMSO

Bioorg Med Chem Lett 15: 4555-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.104
BindingDB Entry DOI: 10.7270/Q2PZ58B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Homo sapiens (Human))		BDBM50171274
PNG
(3-(2-Dimethylamino-ethyl)-2-methyl-1H-indol-4-ol |...)
Show SMILES CN(C)CCc1c(C)[nH]c2cccc(O)c12
Show InChI InChI=1S/C13H18N2O/c1-9-10(7-8-15(2)3)13-11(14-9)5-4-6-12(13)16/h4-6,14,16H,7-8H2,1-3H3
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 122n/an/an/an/an/an/an/an/a



Organix Inc.

Curated by ChEMBL


Assay Description
Inhibition constant against human 5-hydroxytryptamine 2A receptor using [3H]-ketanserin as radioligand with the compound (10 uM) dissolved in DMSO

Bioorg Med Chem Lett 15: 4555-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.104
BindingDB Entry DOI: 10.7270/Q2PZ58B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM50171273
PNG
(3-Dimethylaminomethyl-1-methyl-1H-indol-4-ol | CHE...)
Show SMILES CN(C)Cc1cn(C)c2cccc(O)c12
Show InChI InChI=1S/C12H16N2O/c1-13(2)7-9-8-14(3)10-5-4-6-11(15)12(9)10/h4-6,8,15H,7H2,1-3H3
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 125n/an/an/an/an/an/an/an/a



Organix Inc.

Curated by ChEMBL


Assay Description
Inhibition constant against human 5-hydroxytryptamine 2C receptor [VGI isoforms] using [3H]-mesulergine as radioligand with the compound (10 uM) diss...

Bioorg Med Chem Lett 15: 4555-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.104
BindingDB Entry DOI: 10.7270/Q2PZ58B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM50171271
PNG
(3-(2-Dimethylamino-propyl)-1H-indol-4-ol | CHEMBL1...)
Show SMILES CC(Cc1c[nH]c2cccc(O)c12)N(C)C
Show InChI InChI=1S/C13H18N2O/c1-9(15(2)3)7-10-8-14-11-5-4-6-12(16)13(10)11/h4-6,8-9,14,16H,7H2,1-3H3
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 126n/an/an/an/an/an/an/an/a



Organix Inc.

Curated by ChEMBL


Assay Description
Inhibition constant against human 5-hydroxytryptamine 2C receptor [INI isoforms] using [3H]-mesulergine as radioligand with the compound (10 uM) diss...

Bioorg Med Chem Lett 15: 4555-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.104
BindingDB Entry DOI: 10.7270/Q2PZ58B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2B


(Homo sapiens (Human))		BDBM50171263
PNG
(CHEMBL371753 | Phosphoric acid mono-[1-butyl-3-(2-...)
Show SMILES CCCCn1cc(CCN(C)C)c2c(OP(O)(O)=O)cccc12
Show InChI InChI=1S/C16H25N2O4P/c1-4-5-10-18-12-13(9-11-17(2)3)16-14(18)7-6-8-15(16)22-23(19,20)21/h6-8,12H,4-5,9-11H2,1-3H3,(H2,19,20,21)
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 170n/an/an/an/an/an/an/an/a



Organix Inc.

Curated by ChEMBL


Assay Description
Inhibition constant against human 5-hydroxytryptamine 2B receptor using [3H]-LSD as radioligand with the compound (10 uM) dissolved in DMSO

Bioorg Med Chem Lett 15: 4555-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.104
BindingDB Entry DOI: 10.7270/Q2PZ58B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))		BDBM50171262
PNG
(1-Butyl-3-(2-dimethylamino-ethyl)-1H-indol-4-ol | ...)
Show SMILES CCCCn1cc(CCN(C)C)c2c(O)cccc12
Show InChI InChI=1S/C16H24N2O/c1-4-5-10-18-12-13(9-11-17(2)3)16-14(18)7-6-8-15(16)19/h6-8,12,19H,4-5,9-11H2,1-3H3
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 200n/an/an/an/an/an/an/an/a



Organix Inc.

Curated by ChEMBL


Assay Description
Inhibition constant against rat 5-hydroxytryptamine 2A receptor using [3H]-ketanserin as radioligand with the compound (10 uM) dissolved in DMSO

Bioorg Med Chem Lett 15: 4555-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.104
BindingDB Entry DOI: 10.7270/Q2PZ58B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM50171263
PNG
(CHEMBL371753 | Phosphoric acid mono-[1-butyl-3-(2-...)
Show SMILES CCCCn1cc(CCN(C)C)c2c(OP(O)(O)=O)cccc12
Show InChI InChI=1S/C16H25N2O4P/c1-4-5-10-18-12-13(9-11-17(2)3)16-14(18)7-6-8-15(16)22-23(19,20)21/h6-8,12H,4-5,9-11H2,1-3H3,(H2,19,20,21)
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 210n/an/an/an/an/an/an/an/a



Organix Inc.

Curated by ChEMBL


Assay Description
Inhibition constant against human 5-hydroxytryptamine 2C receptor [VGI isoforms] using [3H]-mesulergine as radioligand with the compound (10 uM) diss...

Bioorg Med Chem Lett 15: 4555-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.104
BindingDB Entry DOI: 10.7270/Q2PZ58B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM50171265
PNG
(3-(2-Pyrrolidin-1-yl-ethyl)-1H-indol-4-ol | CHEMBL...)
Show SMILES Oc1cccc2[nH]cc(CCN3CCCC3)c12
Show InChI InChI=1S/C14H18N2O/c17-13-5-3-4-12-14(13)11(10-15-12)6-9-16-7-1-2-8-16/h3-5,10,15,17H,1-2,6-9H2
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 275n/an/an/an/an/an/an/an/a



Organix Inc.

Curated by ChEMBL


Assay Description
Inhibition constant against human 5-hydroxytryptamine 2C receptor [INI isoforms] using [3H]-mesulergine as radioligand with the compound (10 uM) diss...

Bioorg Med Chem Lett 15: 4555-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.104
BindingDB Entry DOI: 10.7270/Q2PZ58B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Homo sapiens (Human))		BDBM50171262
PNG
(1-Butyl-3-(2-dimethylamino-ethyl)-1H-indol-4-ol | ...)
Show SMILES CCCCn1cc(CCN(C)C)c2c(O)cccc12
Show InChI InChI=1S/C16H24N2O/c1-4-5-10-18-12-13(9-11-17(2)3)16-14(18)7-6-8-15(16)19/h6-8,12,19H,4-5,9-11H2,1-3H3
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 310n/an/an/an/an/an/an/an/a



Organix Inc.

Curated by ChEMBL


Assay Description
Inhibition constant against human 5-hydroxytryptamine 2A receptor using [3H]-ketanserin as radioligand with the compound (10 uM) dissolved in DMSO

Bioorg Med Chem Lett 15: 4555-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.104
BindingDB Entry DOI: 10.7270/Q2PZ58B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Homo sapiens (Human))		BDBM50171264
PNG
(CHEMBL197646 | US11427604, Compound (I-43) | US115...)
Show SMILES CN(C)CCc1c[nH]c2cccc(F)c12
Show InChI InChI=1S/C12H15FN2/c1-15(2)7-6-9-8-14-11-5-3-4-10(13)12(9)11/h3-5,8,14H,6-7H2,1-2H3
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 335n/an/an/an/an/an/an/an/a



Organix Inc.

Curated by ChEMBL


Assay Description
Inhibition constant against human 5-hydroxytryptamine 2A receptor using [3H]-ketanserin as radioligand with the compound (10 uM) dissolved in DMSO

Bioorg Med Chem Lett 15: 4555-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.104
BindingDB Entry DOI: 10.7270/Q2PZ58B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Rattus norvegicus (Rat))		BDBM50171264
PNG
(CHEMBL197646 | US11427604, Compound (I-43) | US115...)
Show SMILES CN(C)CCc1c[nH]c2cccc(F)c12
Show InChI InChI=1S/C12H15FN2/c1-15(2)7-6-9-8-14-11-5-3-4-10(13)12(9)11/h3-5,8,14H,6-7H2,1-2H3
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 359n/an/an/an/an/an/an/an/a



Organix Inc.

Curated by ChEMBL


Assay Description
Inhibition constant against rat 5-hydroxytryptamine 2C receptor using [3H]-mesulergine as radioligand with the compound (10 uM) dissolved in DMSO

Bioorg Med Chem Lett 15: 4555-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.104
BindingDB Entry DOI: 10.7270/Q2PZ58B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2B


(Homo sapiens (Human))		BDBM50171265
PNG
(3-(2-Pyrrolidin-1-yl-ethyl)-1H-indol-4-ol | CHEMBL...)
Show SMILES Oc1cccc2[nH]cc(CCN3CCCC3)c12
Show InChI InChI=1S/C14H18N2O/c17-13-5-3-4-12-14(13)11(10-15-12)6-9-16-7-1-2-8-16/h3-5,10,15,17H,1-2,6-9H2
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 423n/an/an/an/an/an/an/an/a



Organix Inc.

Curated by ChEMBL


Assay Description
Inhibition constant against human 5-hydroxytryptamine 2B receptor using [3H]-LSD as radioligand with the compound (10 uM) dissolved in DMSO

Bioorg Med Chem Lett 15: 4555-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.104
BindingDB Entry DOI: 10.7270/Q2PZ58B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Homo sapiens (Human))		BDBM50171265
PNG
(3-(2-Pyrrolidin-1-yl-ethyl)-1H-indol-4-ol | CHEMBL...)
Show SMILES Oc1cccc2[nH]cc(CCN3CCCC3)c12
Show InChI InChI=1S/C14H18N2O/c17-13-5-3-4-12-14(13)11(10-15-12)6-9-16-7-1-2-8-16/h3-5,10,15,17H,1-2,6-9H2
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 429n/an/an/an/an/an/an/an/a



Organix Inc.

Curated by ChEMBL


Assay Description
Inhibition constant against human 5-hydroxytryptamine 2A receptor using [3H]-ketanserin as radioligand with the compound (10 uM) dissolved in DMSO

Bioorg Med Chem Lett 15: 4555-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.104
BindingDB Entry DOI: 10.7270/Q2PZ58B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM50171267
PNG
(3-[2-(3,4-Dihydro-2H-quinolin-1-yl)-ethyl]-1H-indo...)
Show SMILES Oc1cccc2[nH]cc(CCN3CCCc4ccccc34)c12
Show InChI InChI=1S/C19H20N2O/c22-18-9-3-7-16-19(18)15(13-20-16)10-12-21-11-4-6-14-5-1-2-8-17(14)21/h1-3,5,7-9,13,20,22H,4,6,10-12H2
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 468n/an/an/an/an/an/an/an/a



Organix Inc.

Curated by ChEMBL


Assay Description
Inhibition constant against human 5-hydroxytryptamine 2C receptor [INI isoforms] using [3H]-mesulergine as radioligand with the compound (10 uM) diss...

Bioorg Med Chem Lett 15: 4555-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.104
BindingDB Entry DOI: 10.7270/Q2PZ58B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Homo sapiens (Human))		BDBM50171273
PNG
(3-Dimethylaminomethyl-1-methyl-1H-indol-4-ol | CHE...)
Show SMILES CN(C)Cc1cn(C)c2cccc(O)c12
Show InChI InChI=1S/C12H16N2O/c1-13(2)7-9-8-14(3)10-5-4-6-11(15)12(9)10/h4-6,8,15H,7H2,1-3H3
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 498n/an/an/an/an/an/an/an/a



Organix Inc.

Curated by ChEMBL


Assay Description
Inhibition constant against human 5-hydroxytryptamine 2A receptor using [3H]-ketanserin as radioligand with the compound (10 uM) dissolved in DMSO

Bioorg Med Chem Lett 15: 4555-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.104
BindingDB Entry DOI: 10.7270/Q2PZ58B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM50171274
PNG
(3-(2-Dimethylamino-ethyl)-2-methyl-1H-indol-4-ol |...)
Show SMILES CN(C)CCc1c(C)[nH]c2cccc(O)c12
Show InChI InChI=1S/C13H18N2O/c1-9-10(7-8-15(2)3)13-11(14-9)5-4-6-12(13)16/h4-6,14,16H,7-8H2,1-3H3
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 539n/an/an/an/an/an/an/an/a



Organix Inc.

Curated by ChEMBL


Assay Description
Inhibition constant against human 5-hydroxytryptamine 2C receptor [VGI isoforms] using [3H]-mesulergine as radioligand with the compound (10 uM) diss...

Bioorg Med Chem Lett 15: 4555-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.104
BindingDB Entry DOI: 10.7270/Q2PZ58B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM50171266
PNG
(CHEMBL198123 | Phosphoric acid mono-[3-(2-dimethyl...)
Show SMILES CN(C)CCc1cn(C)c2cccc(OP(O)(O)=O)c12
Show InChI InChI=1S/C13H19N2O4P/c1-14(2)8-7-10-9-15(3)11-5-4-6-12(13(10)11)19-20(16,17)18/h4-6,9H,7-8H2,1-3H3,(H2,16,17,18)
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 540n/an/an/an/an/an/an/an/a



Organix Inc.

Curated by ChEMBL


Assay Description
Inhibition constant against human 5-hydroxytryptamine 2C receptor [VGI isoforms] using [3H]-mesulergine as radioligand with the compound (10 uM) diss...

Bioorg Med Chem Lett 15: 4555-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.104
BindingDB Entry DOI: 10.7270/Q2PZ58B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Homo sapiens (Human))		BDBM50171270
PNG
(3-(3-Dimethylamino-propyl)-1H-indol-4-ol | CHEMBL1...)
Show SMILES CN(C)CCCc1c[nH]c2cccc(O)c12
Show InChI InChI=1S/C13H18N2O/c1-15(2)8-4-5-10-9-14-11-6-3-7-12(16)13(10)11/h3,6-7,9,14,16H,4-5,8H2,1-2H3
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 588n/an/an/an/an/an/an/an/a



Organix Inc.

Curated by ChEMBL


Assay Description
Inhibition constant against human 5-hydroxytryptamine 2A receptor using [3H]-ketanserin as radioligand with the compound (10 uM) dissolved in DMSO

Bioorg Med Chem Lett 15: 4555-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.104
BindingDB Entry DOI: 10.7270/Q2PZ58B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))		BDBM50171261
PNG
(3-(2-Dimethylamino-ethyl)-1-methyl-1H-indol-4-ol |...)
Show SMILES CN(C)CCc1cn(C)c2cccc(O)c12
Show InChI InChI=1S/C13H18N2O/c1-14(2)8-7-10-9-15(3)11-5-4-6-12(16)13(10)11/h4-6,9,16H,7-8H2,1-3H3
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 590n/an/an/an/an/an/an/an/a



Organix Inc.

Curated by ChEMBL


Assay Description
Inhibition constant against rat 5-hydroxytryptamine 2A receptor using [3H]-ketanserin as radioligand with the compound (10 uM) dissolved in DMSO

Bioorg Med Chem Lett 15: 4555-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.104
BindingDB Entry DOI: 10.7270/Q2PZ58B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2B


(Homo sapiens (Human))		BDBM50171271
PNG
(3-(2-Dimethylamino-propyl)-1H-indol-4-ol | CHEMBL1...)
Show SMILES CC(Cc1c[nH]c2cccc(O)c12)N(C)C
Show InChI InChI=1S/C13H18N2O/c1-9(15(2)3)7-10-8-14-11-5-4-6-12(16)13(10)11/h4-6,8-9,14,16H,7H2,1-3H3
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 745n/an/an/an/an/an/an/an/a



Organix Inc.

Curated by ChEMBL


Assay Description
Inhibition constant against human 5-hydroxytryptamine 2B receptor using [3H]-LSD as radioligand with the compound (10 uM) dissolved in DMSO

Bioorg Med Chem Lett 15: 4555-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.104
BindingDB Entry DOI: 10.7270/Q2PZ58B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))		BDBM50171272
PNG
(3-Dimethylaminomethyl-1H-indol-4-ol | CHEMBL194588)
Show SMILES CN(C)Cc1c[nH]c2cccc(O)c12
Show InChI InChI=1S/C11H14N2O/c1-13(2)7-8-6-12-9-4-3-5-10(14)11(8)9/h3-6,12,14H,7H2,1-2H3
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 834n/an/an/an/an/an/an/an/a



Organix Inc.

Curated by ChEMBL


Assay Description
Inhibition constant against rat 5-hydroxytryptamine 2A receptor using [3H]-ketanserin as radioligand with the compound (10 uM) dissolved in DMSO

Bioorg Med Chem Lett 15: 4555-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.104
BindingDB Entry DOI: 10.7270/Q2PZ58B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Homo sapiens (Human))		BDBM50171261
PNG
(3-(2-Dimethylamino-ethyl)-1-methyl-1H-indol-4-ol |...)
Show SMILES CN(C)CCc1cn(C)c2cccc(O)c12
Show InChI InChI=1S/C13H18N2O/c1-14(2)8-7-10-9-15(3)11-5-4-6-12(16)13(10)11/h4-6,9,16H,7-8H2,1-3H3
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 900n/an/an/an/an/an/an/an/a



Organix Inc.

Curated by ChEMBL


Assay Description
Inhibition constant against human 5-hydroxytryptamine 2A receptor using [3H]-ketanserin as radioligand with the compound (10 uM) dissolved in DMSO

Bioorg Med Chem Lett 15: 4555-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.104
BindingDB Entry DOI: 10.7270/Q2PZ58B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Homo sapiens (Human))		BDBM50171272
PNG
(3-Dimethylaminomethyl-1H-indol-4-ol | CHEMBL194588)
Show SMILES CN(C)Cc1c[nH]c2cccc(O)c12
Show InChI InChI=1S/C11H14N2O/c1-13(2)7-8-6-12-9-4-3-5-10(14)11(8)9/h3-6,12,14H,7H2,1-2H3
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 923n/an/an/an/an/an/an/an/a



Organix Inc.

Curated by ChEMBL


Assay Description
Inhibition constant against human 5-hydroxytryptamine 2A receptor using [3H]-ketanserin as radioligand with the compound (10 uM) dissolved in DMSO

Bioorg Med Chem Lett 15: 4555-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.104
BindingDB Entry DOI: 10.7270/Q2PZ58B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Homo sapiens (Human))		BDBM50171271
PNG
(3-(2-Dimethylamino-propyl)-1H-indol-4-ol | CHEMBL1...)
Show SMILES CC(Cc1c[nH]c2cccc(O)c12)N(C)C
Show InChI InChI=1S/C13H18N2O/c1-9(15(2)3)7-10-8-14-11-5-4-6-12(16)13(10)11/h4-6,8-9,14,16H,7H2,1-3H3
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 982n/an/an/an/an/an/an/an/a



Organix Inc.

Curated by ChEMBL


Assay Description
Inhibition constant against human 5-hydroxytryptamine 2A receptor using [3H]-ketanserin as radioligand with the compound (10 uM) dissolved in DMSO

Bioorg Med Chem Lett 15: 4555-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.104
BindingDB Entry DOI: 10.7270/Q2PZ58B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))		BDBM50171264
PNG
(CHEMBL197646 | US11427604, Compound (I-43) | US115...)
Show SMILES CN(C)CCc1c[nH]c2cccc(F)c12
Show InChI InChI=1S/C12H15FN2/c1-15(2)7-6-9-8-14-11-5-3-4-10(13)12(9)11/h3-5,8,14H,6-7H2,1-2H3
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 1.01E+3n/an/an/an/an/an/an/an/a



Organix Inc.

Curated by ChEMBL


Assay Description
Inhibition constant against rat 5-hydroxytryptamine 2A receptor using [3H]-ketanserin as radioligand with the compound (10 uM) dissolved in DMSO

Bioorg Med Chem Lett 15: 4555-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.104
BindingDB Entry DOI: 10.7270/Q2PZ58B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM50171270
PNG
(3-(3-Dimethylamino-propyl)-1H-indol-4-ol | CHEMBL1...)
Show SMILES CN(C)CCCc1c[nH]c2cccc(O)c12
Show InChI InChI=1S/C13H18N2O/c1-15(2)8-4-5-10-9-14-11-6-3-7-12(16)13(10)11/h3,6-7,9,14,16H,4-5,8H2,1-2H3
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 1.11E+3n/an/an/an/an/an/an/an/a



Organix Inc.

Curated by ChEMBL


Assay Description
Inhibition constant against human 5-hydroxytryptamine 2C receptor [INI isoforms] using [3H]-mesulergine as radioligand with the compound (10 uM) diss...

Bioorg Med Chem Lett 15: 4555-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.104
BindingDB Entry DOI: 10.7270/Q2PZ58B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2B


(Homo sapiens (Human))		BDBM50171272
PNG
(3-Dimethylaminomethyl-1H-indol-4-ol | CHEMBL194588)
Show SMILES CN(C)Cc1c[nH]c2cccc(O)c12
Show InChI InChI=1S/C11H14N2O/c1-13(2)7-8-6-12-9-4-3-5-10(14)11(8)9/h3-6,12,14H,7H2,1-2H3
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 1.24E+3n/an/an/an/an/an/an/an/a



Organix Inc.

Curated by ChEMBL


Assay Description
Inhibition constant against human 5-hydroxytryptamine 2B receptor using [3H]-LSD as radioligand with the compound (10 uM) dissolved in DMSO

Bioorg Med Chem Lett 15: 4555-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.104
BindingDB Entry DOI: 10.7270/Q2PZ58B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2B


(Homo sapiens (Human))		BDBM50171273
PNG
(3-Dimethylaminomethyl-1-methyl-1H-indol-4-ol | CHE...)
Show SMILES CN(C)Cc1cn(C)c2cccc(O)c12
Show InChI InChI=1S/C12H16N2O/c1-13(2)7-9-8-14(3)10-5-4-6-11(15)12(9)10/h4-6,8,15H,7H2,1-3H3
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 1.24E+3n/an/an/an/an/an/an/an/a



Organix Inc.

Curated by ChEMBL


Assay Description
Inhibition constant against human 5-hydroxytryptamine 2B receptor using [3H]-LSD as radioligand with the compound (10 uM) dissolved in DMSO

Bioorg Med Chem Lett 15: 4555-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.104
BindingDB Entry DOI: 10.7270/Q2PZ58B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Rattus norvegicus (Rat))		BDBM50171274
PNG
(3-(2-Dimethylamino-ethyl)-2-methyl-1H-indol-4-ol |...)
Show SMILES CN(C)CCc1c(C)[nH]c2cccc(O)c12
Show InChI InChI=1S/C13H18N2O/c1-9-10(7-8-15(2)3)13-11(14-9)5-4-6-12(13)16/h4-6,14,16H,7-8H2,1-3H3
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 1.28E+3n/an/an/an/an/an/an/an/a



Organix Inc.

Curated by ChEMBL


Assay Description
Inhibition constant against rat 5-hydroxytryptamine 2C receptor using [3H]-mesulergine as radioligand with the compound (10 uM) dissolved in DMSO

Bioorg Med Chem Lett 15: 4555-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.104
BindingDB Entry DOI: 10.7270/Q2PZ58B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Rattus norvegicus (Rat))		BDBM50171267
PNG
(3-[2-(3,4-Dihydro-2H-quinolin-1-yl)-ethyl]-1H-indo...)
Show SMILES Oc1cccc2[nH]cc(CCN3CCCc4ccccc34)c12
Show InChI InChI=1S/C19H20N2O/c22-18-9-3-7-16-19(18)15(13-20-16)10-12-21-11-4-6-14-5-1-2-8-17(14)21/h1-3,5,7-9,13,20,22H,4,6,10-12H2
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 1.45E+3n/an/an/an/an/an/an/an/a



Organix Inc.

Curated by ChEMBL


Assay Description
Inhibition constant against rat 5-hydroxytryptamine 2C receptor using [3H]-mesulergine as radioligand with the compound (10 uM) dissolved in DMSO

Bioorg Med Chem Lett 15: 4555-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.104
BindingDB Entry DOI: 10.7270/Q2PZ58B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))		BDBM50171274
PNG
(3-(2-Dimethylamino-ethyl)-2-methyl-1H-indol-4-ol |...)
Show SMILES CN(C)CCc1c(C)[nH]c2cccc(O)c12
Show InChI InChI=1S/C13H18N2O/c1-9-10(7-8-15(2)3)13-11(14-9)5-4-6-12(13)16/h4-6,14,16H,7-8H2,1-3H3
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 1.68E+3n/an/an/an/an/an/an/an/a



Organix Inc.

Curated by ChEMBL


Assay Description
Inhibition constant against rat 5-hydroxytryptamine 2A receptor using [3H]-ketanserin as radioligand with the compound (10 uM) dissolved in DMSO

Bioorg Med Chem Lett 15: 4555-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.104
BindingDB Entry DOI: 10.7270/Q2PZ58B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM50171265
PNG
(3-(2-Pyrrolidin-1-yl-ethyl)-1H-indol-4-ol | CHEMBL...)
Show SMILES Oc1cccc2[nH]cc(CCN3CCCC3)c12
Show InChI InChI=1S/C14H18N2O/c17-13-5-3-4-12-14(13)11(10-15-12)6-9-16-7-1-2-8-16/h3-5,10,15,17H,1-2,6-9H2
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 1.77E+3n/an/an/an/an/an/an/an/a



Organix Inc.

Curated by ChEMBL


Assay Description
Inhibition constant against human 5-hydroxytryptamine 2C receptor [VGI isoforms] using [3H]-mesulergine as radioligand with the compound (10 uM) diss...

Bioorg Med Chem Lett 15: 4555-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.104
BindingDB Entry DOI: 10.7270/Q2PZ58B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM50171268
PNG
(1-(2-Dimethylamino-ethyl)-1H-indol-4-ol | CHEMBL19...)
Show SMILES CN(C)CCn1ccc2c(O)cccc12
Show InChI InChI=1S/C12H16N2O/c1-13(2)8-9-14-7-6-10-11(14)4-3-5-12(10)15/h3-7,15H,8-9H2,1-2H3
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 2.18E+3n/an/an/an/an/an/an/an/a



Organix Inc.

Curated by ChEMBL


Assay Description
Inhibition constant against human 5-hydroxytryptamine 2C receptor [INI isoforms] using [3H]-mesulergine as radioligand with the compound (10 uM) diss...

Bioorg Med Chem Lett 15: 4555-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.104
BindingDB Entry DOI: 10.7270/Q2PZ58B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Homo sapiens (Human))		BDBM50171263
PNG
(CHEMBL371753 | Phosphoric acid mono-[1-butyl-3-(2-...)
Show SMILES CCCCn1cc(CCN(C)C)c2c(OP(O)(O)=O)cccc12
Show InChI InChI=1S/C16H25N2O4P/c1-4-5-10-18-12-13(9-11-17(2)3)16-14(18)7-6-8-15(16)22-23(19,20)21/h6-8,12H,4-5,9-11H2,1-3H3,(H2,19,20,21)
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 3.00E+3n/an/an/an/an/an/an/an/a



Organix Inc.

Curated by ChEMBL


Assay Description
Inhibition constant against human 5-hydroxytryptamine 2A receptor using [3H]-ketanserin as radioligand with the compound (10 uM) dissolved in DMSO

Bioorg Med Chem Lett 15: 4555-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.104
BindingDB Entry DOI: 10.7270/Q2PZ58B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM50171268
PNG
(1-(2-Dimethylamino-ethyl)-1H-indol-4-ol | CHEMBL19...)
Show SMILES CN(C)CCn1ccc2c(O)cccc12
Show InChI InChI=1S/C12H16N2O/c1-13(2)8-9-14-7-6-10-11(14)4-3-5-12(10)15/h3-7,15H,8-9H2,1-2H3
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 4.20E+3n/an/an/an/an/an/an/an/a



Organix Inc.

Curated by ChEMBL


Assay Description
Inhibition constant against human 5-hydroxytryptamine 2C receptor [VGI isoforms] using [3H]-mesulergine as radioligand with the compound (10 uM) diss...

Bioorg Med Chem Lett 15: 4555-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.104
BindingDB Entry DOI: 10.7270/Q2PZ58B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2B


(Homo sapiens (Human))		BDBM50171266
PNG
(CHEMBL198123 | Phosphoric acid mono-[3-(2-dimethyl...)
Show SMILES CN(C)CCc1cn(C)c2cccc(OP(O)(O)=O)c12
Show InChI InChI=1S/C13H19N2O4P/c1-14(2)8-7-10-9-15(3)11-5-4-6-12(13(10)11)19-20(16,17)18/h4-6,9H,7-8H2,1-3H3,(H2,16,17,18)
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 5.50E+3n/an/an/an/an/an/an/an/a



Organix Inc.

Curated by ChEMBL


Assay Description
Inhibition constant against human 5-hydroxytryptamine 2B receptor using [3H]-LSD as radioligand with the compound (10 uM) dissolved in DMSO

Bioorg Med Chem Lett 15: 4555-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.104
BindingDB Entry DOI: 10.7270/Q2PZ58B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2B


(Homo sapiens (Human))		BDBM50171267
PNG
(3-[2-(3,4-Dihydro-2H-quinolin-1-yl)-ethyl]-1H-indo...)
Show SMILES Oc1cccc2[nH]cc(CCN3CCCc4ccccc34)c12
Show InChI InChI=1S/C19H20N2O/c22-18-9-3-7-16-19(18)15(13-20-16)10-12-21-11-4-6-14-5-1-2-8-17(14)21/h1-3,5,7-9,13,20,22H,4,6,10-12H2
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 5.57E+3n/an/an/an/an/an/an/an/a



Organix Inc.

Curated by ChEMBL


Assay Description
Inhibition constant against human 5-hydroxytryptamine 2B receptor using [3H]-LSD as radioligand with the compound (10 uM) dissolved in DMSO

Bioorg Med Chem Lett 15: 4555-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.104
BindingDB Entry DOI: 10.7270/Q2PZ58B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Rattus norvegicus (Rat))		BDBM50171263
PNG
(CHEMBL371753 | Phosphoric acid mono-[1-butyl-3-(2-...)
Show SMILES CCCCn1cc(CCN(C)C)c2c(OP(O)(O)=O)cccc12
Show InChI InChI=1S/C16H25N2O4P/c1-4-5-10-18-12-13(9-11-17(2)3)16-14(18)7-6-8-15(16)22-23(19,20)21/h6-8,12H,4-5,9-11H2,1-3H3,(H2,19,20,21)
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 5.70E+3n/an/an/an/an/an/an/an/a



Organix Inc.

Curated by ChEMBL


Assay Description
Inhibition constant against rat 5-hydroxytryptamine 2C receptor using [3H]-mesulergine as radioligand with the compound (10 uM) dissolved in DMSO

Bioorg Med Chem Lett 15: 4555-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.104
BindingDB Entry DOI: 10.7270/Q2PZ58B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2B


(Homo sapiens (Human))		BDBM50171259
PNG
(3-(2-Dimethylamino-ethyl)-1H-indol-6-ol | CHEMBL38...)
Show SMILES CN(C)CCc1c[nH]c2cc(O)ccc12
Show InChI InChI=1S/C12H16N2O/c1-14(2)6-5-9-8-13-12-7-10(15)3-4-11(9)12/h3-4,7-8,13,15H,5-6H2,1-2H3
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 6.30E+3n/an/an/an/an/an/an/an/a



Organix Inc.

Curated by ChEMBL


Assay Description
Inhibition constant against human 5-hydroxytryptamine 2B receptor using [3H]-LSD as radioligand with the compound (10 uM) dissolved in DMSO

Bioorg Med Chem Lett 15: 4555-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.104
BindingDB Entry DOI: 10.7270/Q2PZ58B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM50171259
PNG
(3-(2-Dimethylamino-ethyl)-1H-indol-6-ol | CHEMBL38...)
Show SMILES CN(C)CCc1c[nH]c2cc(O)ccc12
Show InChI InChI=1S/C12H16N2O/c1-14(2)6-5-9-8-13-12-7-10(15)3-4-11(9)12/h3-4,7-8,13,15H,5-6H2,1-2H3
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 6.80E+3n/an/an/an/an/an/an/an/a



Organix Inc.

Curated by ChEMBL


Assay Description
Inhibition constant against human 5-hydroxytryptamine 2C receptor [VGI isoforms] using [3H]-mesulergine as radioligand with the compound (10 uM) diss...

Bioorg Med Chem Lett 15: 4555-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.104
BindingDB Entry DOI: 10.7270/Q2PZ58B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))		BDBM50171260
PNG
(3-[2-(4-Methyl-piperazin-1-yl)-ethyl]-1H-indol-4-o...)
Show SMILES CN1CCN(CCc2c[nH]c3cccc(O)c23)CC1
Show InChI InChI=1S/C15H21N3O/c1-17-7-9-18(10-8-17)6-5-12-11-16-13-3-2-4-14(19)15(12)13/h2-4,11,16,19H,5-10H2,1H3
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 6.90E+3n/an/an/an/an/an/an/an/a



Organix Inc.

Curated by ChEMBL


Assay Description
Inhibition constant against rat 5-hydroxytryptamine 2A receptor using [3H]-ketanserin as radioligand with the compound (10 uM) dissolved in DMSO

Bioorg Med Chem Lett 15: 4555-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.104
BindingDB Entry DOI: 10.7270/Q2PZ58B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Homo sapiens (Human))		BDBM50171259
PNG
(3-(2-Dimethylamino-ethyl)-1H-indol-6-ol | CHEMBL38...)
Show SMILES CN(C)CCc1c[nH]c2cc(O)ccc12
Show InChI InChI=1S/C12H16N2O/c1-14(2)6-5-9-8-13-12-7-10(15)3-4-11(9)12/h3-4,7-8,13,15H,5-6H2,1-2H3
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 7.60E+3n/an/an/an/an/an/an/an/a



Organix Inc.

Curated by ChEMBL


Assay Description
Inhibition constant against human 5-hydroxytryptamine 2A receptor using [3H]-ketanserin as radioligand with the compound (10 uM) dissolved in DMSO

Bioorg Med Chem Lett 15: 4555-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.104
BindingDB Entry DOI: 10.7270/Q2PZ58B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))		BDBM50171267
PNG
(3-[2-(3,4-Dihydro-2H-quinolin-1-yl)-ethyl]-1H-indo...)
Show SMILES Oc1cccc2[nH]cc(CCN3CCCc4ccccc34)c12
Show InChI InChI=1S/C19H20N2O/c22-18-9-3-7-16-19(18)15(13-20-16)10-12-21-11-4-6-14-5-1-2-8-17(14)21/h1-3,5,7-9,13,20,22H,4,6,10-12H2
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 8.37E+3n/an/an/an/an/an/an/an/a



Organix Inc.

Curated by ChEMBL


Assay Description
Inhibition constant against rat 5-hydroxytryptamine 2A receptor using [3H]-ketanserin as radioligand with the compound (10 uM) dissolved in DMSO

Bioorg Med Chem Lett 15: 4555-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.104
BindingDB Entry DOI: 10.7270/Q2PZ58B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Rattus norvegicus (Rat))		BDBM50171268
PNG
(1-(2-Dimethylamino-ethyl)-1H-indol-4-ol | CHEMBL19...)
Show SMILES CN(C)CCn1ccc2c(O)cccc12
Show InChI InChI=1S/C12H16N2O/c1-13(2)8-9-14-7-6-10-11(14)4-3-5-12(10)15/h3-7,15H,8-9H2,1-2H3
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 9.35E+3n/an/an/an/an/an/an/an/a



Organix Inc.

Curated by ChEMBL


Assay Description
Inhibition constant against rat 5-hydroxytryptamine 2C receptor using [3H]-mesulergine as radioligand with the compound (10 uM) dissolved in DMSO

Bioorg Med Chem Lett 15: 4555-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.104
BindingDB Entry DOI: 10.7270/Q2PZ58B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Homo sapiens (Human))		BDBM50171260
PNG
(3-[2-(4-Methyl-piperazin-1-yl)-ethyl]-1H-indol-4-o...)
Show SMILES CN1CCN(CCc2c[nH]c3cccc(O)c23)CC1
Show InChI InChI=1S/C15H21N3O/c1-17-7-9-18(10-8-17)6-5-12-11-16-13-3-2-4-14(19)15(12)13/h2-4,11,16,19H,5-10H2,1H3
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 9.75E+3n/an/an/an/an/an/an/an/a



Organix Inc.

Curated by ChEMBL


Assay Description
Inhibition constant against human 5-hydroxytryptamine 2A receptor using [3H]-ketanserin as radioligand with the compound (10 uM) dissolved in DMSO

Bioorg Med Chem Lett 15: 4555-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.104
BindingDB Entry DOI: 10.7270/Q2PZ58B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Homo sapiens (Human))		BDBM50171266
PNG
(CHEMBL198123 | Phosphoric acid mono-[3-(2-dimethyl...)
Show SMILES CN(C)CCc1cn(C)c2cccc(OP(O)(O)=O)c12
Show InChI InChI=1S/C13H19N2O4P/c1-14(2)8-7-10-9-15(3)11-5-4-6-12(13(10)11)19-20(16,17)18/h4-6,9H,7-8H2,1-3H3,(H2,16,17,18)
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>1.00E+4n/an/an/an/an/an/an/an/a



Organix Inc.

Curated by ChEMBL


Assay Description
Inhibition constant against human 5-hydroxytryptamine 2A receptor using [3H]-ketanserin as radioligand with the compound (10 uM) dissolved in DMSO

Bioorg Med Chem Lett 15: 4555-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.104
BindingDB Entry DOI: 10.7270/Q2PZ58B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM50171259
PNG
(3-(2-Dimethylamino-ethyl)-1H-indol-6-ol | CHEMBL38...)
Show SMILES CN(C)CCc1c[nH]c2cc(O)ccc12
Show InChI InChI=1S/C12H16N2O/c1-14(2)6-5-9-8-13-12-7-10(15)3-4-11(9)12/h3-4,7-8,13,15H,5-6H2,1-2H3
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>1.00E+4n/an/an/an/an/an/an/an/a



Organix Inc.

Curated by ChEMBL


Assay Description
Inhibition constant against human 5-hydroxytryptamine 2C receptor [INI isoforms] using [3H]-mesulergine as radioligand with the compound (10 uM) diss...

Bioorg Med Chem Lett 15: 4555-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.104
BindingDB Entry DOI: 10.7270/Q2PZ58B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))		BDBM50171266
PNG
(CHEMBL198123 | Phosphoric acid mono-[3-(2-dimethyl...)
Show SMILES CN(C)CCc1cn(C)c2cccc(OP(O)(O)=O)c12
Show InChI InChI=1S/C13H19N2O4P/c1-14(2)8-7-10-9-15(3)11-5-4-6-12(13(10)11)19-20(16,17)18/h4-6,9H,7-8H2,1-3H3,(H2,16,17,18)
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>1.00E+4n/an/an/an/an/an/an/an/a



Organix Inc.

Curated by ChEMBL


Assay Description
Inhibition constant against rat 5-hydroxytryptamine 2A receptor using [3H]-ketanserin as radioligand with the compound (10 uM) dissolved in DMSO

Bioorg Med Chem Lett 15: 4555-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.104
BindingDB Entry DOI: 10.7270/Q2PZ58B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM50171266
PNG
(CHEMBL198123 | Phosphoric acid mono-[3-(2-dimethyl...)
Show SMILES CN(C)CCc1cn(C)c2cccc(OP(O)(O)=O)c12
Show InChI InChI=1S/C13H19N2O4P/c1-14(2)8-7-10-9-15(3)11-5-4-6-12(13(10)11)19-20(16,17)18/h4-6,9H,7-8H2,1-3H3,(H2,16,17,18)
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>1.00E+4n/an/an/an/an/an/an/an/a



Organix Inc.

Curated by ChEMBL


Assay Description
Inhibition constant against human 5-hydroxytryptamine 2C receptor [INI isoforms] using [3H]-mesulergine as radioligand with the compound (10 uM) diss...

Bioorg Med Chem Lett 15: 4555-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.104
BindingDB Entry DOI: 10.7270/Q2PZ58B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Rattus norvegicus (Rat))		BDBM50171260
PNG
(3-[2-(4-Methyl-piperazin-1-yl)-ethyl]-1H-indol-4-o...)
Show SMILES CN1CCN(CCc2c[nH]c3cccc(O)c23)CC1
Show InChI InChI=1S/C15H21N3O/c1-17-7-9-18(10-8-17)6-5-12-11-16-13-3-2-4-14(19)15(12)13/h2-4,11,16,19H,5-10H2,1H3
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>1.00E+4n/an/an/an/an/an/an/an/a



Organix Inc.

Curated by ChEMBL


Assay Description
Inhibition constant against rat 5-hydroxytryptamine 2C receptor using [3H]-mesulergine as radioligand with the compound (10 uM) dissolved in DMSO

Bioorg Med Chem Lett 15: 4555-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.104
BindingDB Entry DOI: 10.7270/Q2PZ58B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Rattus norvegicus (Rat))		BDBM50171266
PNG
(CHEMBL198123 | Phosphoric acid mono-[3-(2-dimethyl...)
Show SMILES CN(C)CCc1cn(C)c2cccc(OP(O)(O)=O)c12
Show InChI InChI=1S/C13H19N2O4P/c1-14(2)8-7-10-9-15(3)11-5-4-6-12(13(10)11)19-20(16,17)18/h4-6,9H,7-8H2,1-3H3,(H2,16,17,18)
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>1.00E+4n/an/an/an/an/an/an/an/a



Organix Inc.

Curated by ChEMBL


Assay Description
Inhibition constant against rat 5-hydroxytryptamine 2C receptor using [3H]-mesulergine as radioligand with the compound (10 uM) dissolved in DMSO

Bioorg Med Chem Lett 15: 4555-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.104
BindingDB Entry DOI: 10.7270/Q2PZ58B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))		BDBM50171263
PNG
(CHEMBL371753 | Phosphoric acid mono-[1-butyl-3-(2-...)
Show SMILES CCCCn1cc(CCN(C)C)c2c(OP(O)(O)=O)cccc12
Show InChI InChI=1S/C16H25N2O4P/c1-4-5-10-18-12-13(9-11-17(2)3)16-14(18)7-6-8-15(16)22-23(19,20)21/h6-8,12H,4-5,9-11H2,1-3H3,(H2,19,20,21)
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>1.00E+4n/an/an/an/an/an/an/an/a



Organix Inc.

Curated by ChEMBL


Assay Description
Inhibition constant against rat 5-hydroxytryptamine 2A receptor using [3H]-ketanserin as radioligand with the compound (10 uM) dissolved in DMSO

Bioorg Med Chem Lett 15: 4555-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.104
BindingDB Entry DOI: 10.7270/Q2PZ58B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))		BDBM50171259
PNG
(3-(2-Dimethylamino-ethyl)-1H-indol-6-ol | CHEMBL38...)
Show SMILES CN(C)CCc1c[nH]c2cc(O)ccc12
Show InChI InChI=1S/C12H16N2O/c1-14(2)6-5-9-8-13-12-7-10(15)3-4-11(9)12/h3-4,7-8,13,15H,5-6H2,1-2H3
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>1.00E+4n/an/an/an/an/an/an/an/a



Organix Inc.

Curated by ChEMBL


Assay Description
Inhibition constant against rat 5-hydroxytryptamine 2A receptor using [3H]-ketanserin as radioligand with the compound (10 uM) dissolved in DMSO

Bioorg Med Chem Lett 15: 4555-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.104
BindingDB Entry DOI: 10.7270/Q2PZ58B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))		BDBM50171268
PNG
(1-(2-Dimethylamino-ethyl)-1H-indol-4-ol | CHEMBL19...)
Show SMILES CN(C)CCn1ccc2c(O)cccc12
Show InChI InChI=1S/C12H16N2O/c1-13(2)8-9-14-7-6-10-11(14)4-3-5-12(10)15/h3-7,15H,8-9H2,1-2H3
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>1.00E+4n/an/an/an/an/an/an/an/a



Organix Inc.

Curated by ChEMBL


Assay Description
Inhibition constant against rat 5-hydroxytryptamine 2A receptor using [3H]-ketanserin as radioligand with the compound (10 uM) dissolved in DMSO

Bioorg Med Chem Lett 15: 4555-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.104
BindingDB Entry DOI: 10.7270/Q2PZ58B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Rattus norvegicus (Rat))		BDBM50171259
PNG
(3-(2-Dimethylamino-ethyl)-1H-indol-6-ol | CHEMBL38...)
Show SMILES CN(C)CCc1c[nH]c2cc(O)ccc12
Show InChI InChI=1S/C12H16N2O/c1-14(2)6-5-9-8-13-12-7-10(15)3-4-11(9)12/h3-4,7-8,13,15H,5-6H2,1-2H3
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 1.90E+4n/an/an/an/an/an/an/an/a



Organix Inc.

Curated by ChEMBL


Assay Description
Inhibition constant against rat 5-hydroxytryptamine 2C receptor using [3H]-mesulergine as radioligand with the compound (10 uM) dissolved in DMSO

Bioorg Med Chem Lett 15: 4555-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.104
BindingDB Entry DOI: 10.7270/Q2PZ58B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM50171262
PNG
(1-Butyl-3-(2-dimethylamino-ethyl)-1H-indol-4-ol | ...)
Show SMILES CCCCn1cc(CCN(C)C)c2c(O)cccc12
Show InChI InChI=1S/C16H24N2O/c1-4-5-10-18-12-13(9-11-17(2)3)16-14(18)7-6-8-15(16)19/h6-8,12,19H,4-5,9-11H2,1-3H3
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n/an/an/an/a 595n/an/an/an/a



Organix Inc.

Curated by ChEMBL


Assay Description
Effective concentration required for accumulation of [3H]-inositol phosphate in cells stably expressing human 5-hydroxytryptamine 2C receptor determi...

Bioorg Med Chem Lett 15: 4555-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.104
BindingDB Entry DOI: 10.7270/Q2PZ58B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Homo sapiens (Human))		BDBM50171262
PNG
(1-Butyl-3-(2-dimethylamino-ethyl)-1H-indol-4-ol | ...)
Show SMILES CCCCn1cc(CCN(C)C)c2c(O)cccc12
Show InChI InChI=1S/C16H24N2O/c1-4-5-10-18-12-13(9-11-17(2)3)16-14(18)7-6-8-15(16)19/h6-8,12,19H,4-5,9-11H2,1-3H3
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n/an/an/an/a 32n/an/an/an/a



Organix Inc.

Curated by ChEMBL


Assay Description
Effective concentration required for accumulation of [3H]-inositol phosphate in cells stably expressing human 5-hydroxytryptamine 2A receptor determi...

Bioorg Med Chem Lett 15: 4555-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.104
BindingDB Entry DOI: 10.7270/Q2PZ58B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Homo sapiens (Human))		BDBM50171264
PNG
(CHEMBL197646 | US11427604, Compound (I-43) | US115...)
Show SMILES CN(C)CCc1c[nH]c2cccc(F)c12
Show InChI InChI=1S/C12H15FN2/c1-15(2)7-6-9-8-14-11-5-3-4-10(13)12(9)11/h3-5,8,14H,6-7H2,1-2H3
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n/an/an/an/a 949n/an/an/an/a



Organix Inc.

Curated by ChEMBL


Assay Description
Effective concentration required for accumulation of [3H]-inositol phosphate in cells stably expressing human 5-hydroxytryptamine 2A receptor determi...

Bioorg Med Chem Lett 15: 4555-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.104
BindingDB Entry DOI: 10.7270/Q2PZ58B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Homo sapiens (Human))		BDBM50171261
PNG
(3-(2-Dimethylamino-ethyl)-1-methyl-1H-indol-4-ol |...)
Show SMILES CN(C)CCc1cn(C)c2cccc(O)c12
Show InChI InChI=1S/C13H18N2O/c1-14(2)8-7-10-9-15(3)11-5-4-6-12(16)13(10)11/h4-6,9,16H,7-8H2,1-3H3
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n/an/an/an/a 633n/an/an/an/a



Organix Inc.

Curated by ChEMBL


Assay Description
Effective concentration required for accumulation of [3H]-inositol phosphate in cells stably expressing human 5-hydroxytryptamine 2A receptor determi...

Bioorg Med Chem Lett 15: 4555-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.104
BindingDB Entry DOI: 10.7270/Q2PZ58B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2B


(Homo sapiens (Human))		BDBM50171264
PNG
(CHEMBL197646 | US11427604, Compound (I-43) | US115...)
Show SMILES CN(C)CCc1c[nH]c2cccc(F)c12
Show InChI InChI=1S/C12H15FN2/c1-15(2)7-6-9-8-14-11-5-3-4-10(13)12(9)11/h3-5,8,14H,6-7H2,1-2H3
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n/an/an/an/a 1.18E+3n/an/an/an/a



Organix Inc.

Curated by ChEMBL


Assay Description
Effective concentration required for accumulation of [3H]-inositol phosphate in cells transiently expressing human 5-hydroxytryptamine 2B receptor de...

Bioorg Med Chem Lett 15: 4555-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.104
BindingDB Entry DOI: 10.7270/Q2PZ58B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2B


(Homo sapiens (Human))		BDBM50171269
PNG
(3-[2-(dimethylamino)ethyl]-1H-indol-4-yl dihydroge...)
Show SMILES CN(C)CCc1c[nH]c2cccc(OP(O)(O)=O)c12
Show InChI InChI=1S/C12H17N2O4P/c1-14(2)7-6-9-8-13-10-4-3-5-11(12(9)10)18-19(15,16)17/h3-5,8,13H,6-7H2,1-2H3,(H2,15,16,17)
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n/an/an/an/a 74n/an/an/an/a



Organix Inc.

Curated by ChEMBL


Assay Description
Effective concentration required for accumulation of [3H]-inositol phosphate in cells transiently expressing human 5-hydroxytryptamine 2B receptor de...

Bioorg Med Chem Lett 15: 4555-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.104
BindingDB Entry DOI: 10.7270/Q2PZ58B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Homo sapiens (Human))		BDBM50081701
PNG
(3-[2-(dimethylamino)ethyl]-1H-indol-4-ol | 4-hydro...)
Show SMILES CN(C)CCc1c[nH]c2cccc(O)c12
Show InChI InChI=1S/C12H16N2O/c1-14(2)7-6-9-8-13-10-4-3-5-11(15)12(9)10/h3-5,8,13,15H,6-7H2,1-2H3
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n/an/an/an/a 24n/an/an/an/a



Organix Inc.

Curated by ChEMBL


Assay Description
Effective concentration required for accumulation of [3H]-inositol phosphate in cells stably expressing human 5-hydroxytryptamine 2A receptor determi...

Bioorg Med Chem Lett 15: 4555-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.104
BindingDB Entry DOI: 10.7270/Q2PZ58B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM50171269
PNG
(3-[2-(dimethylamino)ethyl]-1H-indol-4-yl dihydroge...)
Show SMILES CN(C)CCc1c[nH]c2cccc(OP(O)(O)=O)c12
Show InChI InChI=1S/C12H17N2O4P/c1-14(2)7-6-9-8-13-10-4-3-5-11(12(9)10)18-19(15,16)17/h3-5,8,13H,6-7H2,1-2H3,(H2,15,16,17)
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n/an/an/an/a 506n/an/an/an/a



Organix Inc.

Curated by ChEMBL


Assay Description
Effective concentration required for accumulation of [3H]-inositol phosphate in cells stably expressing human 5-hydroxytryptamine 2C receptor determi...

Bioorg Med Chem Lett 15: 4555-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.104
BindingDB Entry DOI: 10.7270/Q2PZ58B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM50171261
PNG
(3-(2-Dimethylamino-ethyl)-1-methyl-1H-indol-4-ol |...)
Show SMILES CN(C)CCc1cn(C)c2cccc(O)c12
Show InChI InChI=1S/C13H18N2O/c1-14(2)8-7-10-9-15(3)11-5-4-6-12(16)13(10)11/h4-6,9,16H,7-8H2,1-3H3
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n/an/an/an/a 12n/an/an/an/a



Organix Inc.

Curated by ChEMBL


Assay Description
Effective concentration required for accumulation of [3H]-inositol phosphate in cells stably expressing human 5-hydroxytryptamine 2C receptor determi...

Bioorg Med Chem Lett 15: 4555-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.104
BindingDB Entry DOI: 10.7270/Q2PZ58B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM50171264
PNG
(CHEMBL197646 | US11427604, Compound (I-43) | US115...)
Show SMILES CN(C)CCc1c[nH]c2cccc(F)c12
Show InChI InChI=1S/C12H15FN2/c1-15(2)7-6-9-8-14-11-5-3-4-10(13)12(9)11/h3-5,8,14H,6-7H2,1-2H3
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n/an/an/an/a 99n/an/an/an/a



Organix Inc.

Curated by ChEMBL


Assay Description
Effective concentration required for accumulation of [3H]-inositol phosphate in cells stably expressing human 5-hydroxytryptamine 2C receptor determi...

Bioorg Med Chem Lett 15: 4555-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.104
BindingDB Entry DOI: 10.7270/Q2PZ58B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2B


(Homo sapiens (Human))		BDBM50081701
PNG
(3-[2-(dimethylamino)ethyl]-1H-indol-4-ol | 4-hydro...)
Show SMILES CN(C)CCc1c[nH]c2cccc(O)c12
Show InChI InChI=1S/C12H16N2O/c1-14(2)7-6-9-8-13-10-4-3-5-11(15)12(9)10/h3-5,8,13,15H,6-7H2,1-2H3
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n/an/an/an/a 58n/an/an/an/a



Organix Inc.

Curated by ChEMBL


Assay Description
Effective concentration required for accumulation of [3H]-inositol phosphate in cells transiently expressing human 5-hydroxytryptamine 2B receptor de...

Bioorg Med Chem Lett 15: 4555-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.104
BindingDB Entry DOI: 10.7270/Q2PZ58B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Homo sapiens (Human))		BDBM50171269
PNG
(3-[2-(dimethylamino)ethyl]-1H-indol-4-yl dihydroge...)
Show SMILES CN(C)CCc1c[nH]c2cccc(OP(O)(O)=O)c12
Show InChI InChI=1S/C12H17N2O4P/c1-14(2)7-6-9-8-13-10-4-3-5-11(12(9)10)18-19(15,16)17/h3-5,8,13H,6-7H2,1-2H3,(H2,15,16,17)
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n/an/an/an/a 3.48E+3n/an/an/an/a



Organix Inc.

Curated by ChEMBL


Assay Description
Effective concentration required for accumulation of [3H]-inositol phosphate in cells stably expressing human 5-hydroxytryptamine 2A receptor determi...

Bioorg Med Chem Lett 15: 4555-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.104
BindingDB Entry DOI: 10.7270/Q2PZ58B5
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM50081701
PNG
(3-[2-(dimethylamino)ethyl]-1H-indol-4-ol | 4-hydro...)
Show SMILES CN(C)CCc1c[nH]c2cccc(O)c12
Show InChI InChI=1S/C12H16N2O/c1-14(2)7-6-9-8-13-10-4-3-5-11(15)12(9)10/h3-5,8,13,15H,6-7H2,1-2H3
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n/an/an/an/a 30n/an/an/an/a



Organix Inc.

Curated by ChEMBL


Assay Description
Effective concentration required for accumulation of [3H]-inositol phosphate in cells stably expressing human 5-hydroxytryptamine 2C receptor determi...

Bioorg Med Chem Lett 15: 4555-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.104
BindingDB Entry DOI: 10.7270/Q2PZ58B5
More data for this
Ligand-Target Pair		3D
3D Structure (crystal)
* indicates data uncertainty>20%