Affinity Data by PubMed id=17988766

PubMed code 17988766

Found 26 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50265433 (1-Isobutyl-4-phenylpiperidine-4-carbonitrile \| CHE...) Show SMILES CC(C)CN1CCC(CC1)(C#N)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.350	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Displacement of [3H](+)-pentazocine from sigma 1 opioid receptor in rat brain cerebellum				Eur J Med Chem 43: 1304-8 (2008) Article DOI: 10.1016/j.ejmech.2007.09.026 BindingDB Entry DOI: 10.7270/Q2W37W3G
University of Maryland Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50265436 (1-Phenylpropyl-4-phenylpiperidine-4-carbonitrile \|...) Show SMILES N#CC1(CCN(CCCc2ccccc2)CC1)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.380	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Displacement of [3H](+)-pentazocine from sigma 1 opioid receptor in rat brain cerebellum				Eur J Med Chem 43: 1304-8 (2008) Article DOI: 10.1016/j.ejmech.2007.09.026 BindingDB Entry DOI: 10.7270/Q2W37W3G
University of Maryland Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50265434 (1-Benzyl-4-phenylpiperidine-4-carbonitrile \| CHEMB...) Show SMILES N#CC1(CCN(Cc2ccccc2)CC1)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	0.410	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Displacement of [3H](+)-pentazocine from sigma 1 opioid receptor in rat brain cerebellum				Eur J Med Chem 43: 1304-8 (2008) Article DOI: 10.1016/j.ejmech.2007.09.026 BindingDB Entry DOI: 10.7270/Q2W37W3G
University of Maryland Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50265407 (1-Propyl-4-phenylpiperidine-4-carbonitrile \| CHEMB...) Show SMILES CCCN1CCC(CC1)(C#N)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Displacement of [3H](+)-pentazocine from sigma 1 opioid receptor in rat brain cerebellum				Eur J Med Chem 43: 1304-8 (2008) Article DOI: 10.1016/j.ejmech.2007.09.026 BindingDB Entry DOI: 10.7270/Q2W37W3G
University of Maryland Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50265406 (1-Allyl-4-phenylpiperidine-4-carbonitrile \| CHEMBL...) Show SMILES C=CCN1CCC(CC1)(C#N)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Displacement of [3H](+)-pentazocine from sigma 1 opioid receptor in rat brain cerebellum				Eur J Med Chem 43: 1304-8 (2008) Article DOI: 10.1016/j.ejmech.2007.09.026 BindingDB Entry DOI: 10.7270/Q2W37W3G
University of Maryland Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50265435 (1-Phenylethyl-4-phenylpiperidine-4-carbonitrile \| ...) Show SMILES N#CC1(CCN(CCc2ccccc2)CC1)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Displacement of [3H](+)-pentazocine from sigma 1 opioid receptor in rat brain cerebellum				Eur J Med Chem 43: 1304-8 (2008) Article DOI: 10.1016/j.ejmech.2007.09.026 BindingDB Entry DOI: 10.7270/Q2W37W3G
University of Maryland Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50265432 (1-(2-Methylallyl)-4-phenylpiperidine-4-carbonitril...) Show SMILES CC(=C)CN1CCC(CC1)(C#N)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Displacement of [3H](+)-pentazocine from sigma 1 opioid receptor in rat brain cerebellum				Eur J Med Chem 43: 1304-8 (2008) Article DOI: 10.1016/j.ejmech.2007.09.026 BindingDB Entry DOI: 10.7270/Q2W37W3G
University of Maryland Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50109389 (1-Phenethyl-piperidine \| 1-phenethylpiperidine \| C...) Show SMILES C(Cc1ccccc1)N1CCCCC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Displacement of [3H](+)-pentazocine from sigma 1 opioid receptor in rat brain cerebellum				Eur J Med Chem 43: 1304-8 (2008) Article DOI: 10.1016/j.ejmech.2007.09.026 BindingDB Entry DOI: 10.7270/Q2W37W3G
University of Maryland Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50265437 (1-Phenylbutyl-4-phenylpiperidine-4-carbonitrile \| ...) Show SMILES N#CC1(CCN(CCCCc2ccccc2)CC1)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	49	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Displacement of [3H](+)-pentazocine from sigma 1 opioid receptor in rat brain cerebellum				Eur J Med Chem 43: 1304-8 (2008) Article DOI: 10.1016/j.ejmech.2007.09.026 BindingDB Entry DOI: 10.7270/Q2W37W3G
University of Maryland Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50265405 (1-Methyl-4-phenylpiperidine-4-carbonitrile \| CHEMB...) Show SMILES CN1CCC(CC1)(C#N)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	113	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Displacement of [3H](+)-pentazocine from sigma 1 opioid receptor in rat brain cerebellum				Eur J Med Chem 43: 1304-8 (2008) Article DOI: 10.1016/j.ejmech.2007.09.026 BindingDB Entry DOI: 10.7270/Q2W37W3G
University of Maryland Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50109388 (1-(2-phenylethyl)-4-(2-pyridyl)piperazine \| 1-Phen...) Show SMILES C(Cc1ccccc1)N1CCN(CC1)c1ccccn1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	322	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Displacement of [3H](+)-pentazocine from sigma 1 opioid receptor in rat brain cerebellum				Eur J Med Chem 43: 1304-8 (2008) Article DOI: 10.1016/j.ejmech.2007.09.026 BindingDB Entry DOI: 10.7270/Q2W37W3G
University of Maryland Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50265432 (1-(2-Methylallyl)-4-phenylpiperidine-4-carbonitril...) Show SMILES CC(=C)CN1CCC(CC1)(C#N)c1ccccc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Binding affinity to delta opioid receptor				Eur J Med Chem 43: 1304-8 (2008) Article DOI: 10.1016/j.ejmech.2007.09.026 BindingDB Entry DOI: 10.7270/Q2W37W3G
University of Maryland Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50265434 (1-Benzyl-4-phenylpiperidine-4-carbonitrile \| CHEMB...) Show SMILES N#CC1(CCN(Cc2ccccc2)CC1)c1ccccc1 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	5.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Binding affinity to mu opioid receptor				Eur J Med Chem 43: 1304-8 (2008) Article DOI: 10.1016/j.ejmech.2007.09.026 BindingDB Entry DOI: 10.7270/Q2W37W3G
University of Maryland Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50265437 (1-Phenylbutyl-4-phenylpiperidine-4-carbonitrile \| ...) Show SMILES N#CC1(CCN(CCCCc2ccccc2)CC1)c1ccccc1 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Binding affinity to mu opioid receptor				Eur J Med Chem 43: 1304-8 (2008) Article DOI: 10.1016/j.ejmech.2007.09.026 BindingDB Entry DOI: 10.7270/Q2W37W3G
University of Maryland Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50265437 (1-Phenylbutyl-4-phenylpiperidine-4-carbonitrile \| ...) Show SMILES N#CC1(CCN(CCCCc2ccccc2)CC1)c1ccccc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Binding affinity to delta opioid receptor				Eur J Med Chem 43: 1304-8 (2008) Article DOI: 10.1016/j.ejmech.2007.09.026 BindingDB Entry DOI: 10.7270/Q2W37W3G
University of Maryland Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50265406 (1-Allyl-4-phenylpiperidine-4-carbonitrile \| CHEMBL...) Show SMILES C=CCN1CCC(CC1)(C#N)c1ccccc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Binding affinity to delta opioid receptor				Eur J Med Chem 43: 1304-8 (2008) Article DOI: 10.1016/j.ejmech.2007.09.026 BindingDB Entry DOI: 10.7270/Q2W37W3G
University of Maryland Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50265437 (1-Phenylbutyl-4-phenylpiperidine-4-carbonitrile \| ...) Show SMILES N#CC1(CCN(CCCCc2ccccc2)CC1)c1ccccc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Binding affinity to kappa opioid receptor				Eur J Med Chem 43: 1304-8 (2008) Article DOI: 10.1016/j.ejmech.2007.09.026 BindingDB Entry DOI: 10.7270/Q2W37W3G
University of Maryland Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50265405 (1-Methyl-4-phenylpiperidine-4-carbonitrile \| CHEMB...) Show SMILES CN1CCC(CC1)(C#N)c1ccccc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Binding affinity to delta opioid receptor				Eur J Med Chem 43: 1304-8 (2008) Article DOI: 10.1016/j.ejmech.2007.09.026 BindingDB Entry DOI: 10.7270/Q2W37W3G
University of Maryland Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50265405 (1-Methyl-4-phenylpiperidine-4-carbonitrile \| CHEMB...) Show SMILES CN1CCC(CC1)(C#N)c1ccccc1 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Binding affinity to mu opioid receptor				Eur J Med Chem 43: 1304-8 (2008) Article DOI: 10.1016/j.ejmech.2007.09.026 BindingDB Entry DOI: 10.7270/Q2W37W3G
University of Maryland Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50265432 (1-(2-Methylallyl)-4-phenylpiperidine-4-carbonitril...) Show SMILES CC(=C)CN1CCC(CC1)(C#N)c1ccccc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Binding affinity to kappa opioid receptor				Eur J Med Chem 43: 1304-8 (2008) Article DOI: 10.1016/j.ejmech.2007.09.026 BindingDB Entry DOI: 10.7270/Q2W37W3G
University of Maryland Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50265432 (1-(2-Methylallyl)-4-phenylpiperidine-4-carbonitril...) Show SMILES CC(=C)CN1CCC(CC1)(C#N)c1ccccc1 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Binding affinity to mu opioid receptor				Eur J Med Chem 43: 1304-8 (2008) Article DOI: 10.1016/j.ejmech.2007.09.026 BindingDB Entry DOI: 10.7270/Q2W37W3G
University of Maryland Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50265434 (1-Benzyl-4-phenylpiperidine-4-carbonitrile \| CHEMB...) Show SMILES N#CC1(CCN(Cc2ccccc2)CC1)c1ccccc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Binding affinity to kappa opioid receptor				Eur J Med Chem 43: 1304-8 (2008) Article DOI: 10.1016/j.ejmech.2007.09.026 BindingDB Entry DOI: 10.7270/Q2W37W3G
University of Maryland Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50265405 (1-Methyl-4-phenylpiperidine-4-carbonitrile \| CHEMB...) Show SMILES CN1CCC(CC1)(C#N)c1ccccc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Binding affinity to kappa opioid receptor				Eur J Med Chem 43: 1304-8 (2008) Article DOI: 10.1016/j.ejmech.2007.09.026 BindingDB Entry DOI: 10.7270/Q2W37W3G
University of Maryland Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50265406 (1-Allyl-4-phenylpiperidine-4-carbonitrile \| CHEMBL...) Show SMILES C=CCN1CCC(CC1)(C#N)c1ccccc1 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Binding affinity to mu opioid receptor				Eur J Med Chem 43: 1304-8 (2008) Article DOI: 10.1016/j.ejmech.2007.09.026 BindingDB Entry DOI: 10.7270/Q2W37W3G
University of Maryland Curated by ChEMBL					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50265434 (1-Benzyl-4-phenylpiperidine-4-carbonitrile \| CHEMB...) Show SMILES N#CC1(CCN(Cc2ccccc2)CC1)c1ccccc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Binding affinity to delta opioid receptor				Eur J Med Chem 43: 1304-8 (2008) Article DOI: 10.1016/j.ejmech.2007.09.026 BindingDB Entry DOI: 10.7270/Q2W37W3G
University of Maryland Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50265406 (1-Allyl-4-phenylpiperidine-4-carbonitrile \| CHEMBL...) Show SMILES C=CCN1CCC(CC1)(C#N)c1ccccc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Binding affinity to kappa opioid receptor				Eur J Med Chem 43: 1304-8 (2008) Article DOI: 10.1016/j.ejmech.2007.09.026 BindingDB Entry DOI: 10.7270/Q2W37W3G
University of Maryland Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%