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PubMed code 21295477

Compile data set for download or QSAR
Found 24 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sphingosine 1-phosphate receptor 1


(Homo sapiens (Human))
BDBM50337597
PNG
(CHEMBL1683047 | trans-3-(3-(4-(3-phenylpropoxy)phe...)
Show SMILES C\C(=C/CNCCC(O)=O)c1ccc(OCCCc2ccccc2)cc1
Show InChI InChI=1S/C22H27NO3/c1-18(13-15-23-16-14-22(24)25)20-9-11-21(12-10-20)26-17-5-8-19-6-3-2-4-7-19/h2-4,6-7,9-13,23H,5,8,14-17H2,1H3,(H,24,25)/b18-13+
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n/an/an/an/a 21n/an/an/an/a



Ono Pharmaceutical Co., Ltd

Curated by ChEMBL


Assay Description
Agonist activity at human S1P1 receptor expressed in CHO cells assessed as intracellular calcium levels


Bioorg Med Chem Lett 21: 1390-3 (2011)


Article DOI: 10.1016/j.bmcl.2011.01.029
BindingDB Entry DOI: 10.7270/Q26973VP
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 1


(Homo sapiens (Human))
BDBM50337590
PNG
(3-(3-(4-(4-phenylbutoxy)phenyl)propylamino)propano...)
Show SMILES OC(=O)CCNCCCc1ccc(OCCCCc2ccccc2)cc1
Show InChI InChI=1S/C22H29NO3/c24-22(25)15-17-23-16-6-10-20-11-13-21(14-12-20)26-18-5-4-9-19-7-2-1-3-8-19/h1-3,7-8,11-14,23H,4-6,9-10,15-18H2,(H,24,25)
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n/an/an/an/a 1.50E+3n/an/an/an/a



Ono Pharmaceutical Co., Ltd

Curated by ChEMBL


Assay Description
Agonist activity at human S1P1 receptor expressed in CHO cells assessed as intracellular calcium levels


Bioorg Med Chem Lett 21: 1390-3 (2011)


Article DOI: 10.1016/j.bmcl.2011.01.029
BindingDB Entry DOI: 10.7270/Q26973VP
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 1


(Homo sapiens (Human))
BDBM50337591
PNG
(3-(3-(4-(3-phenylpropoxy)phenyl)propylamino)propan...)
Show SMILES OC(=O)CCNCCCc1ccc(OCCCc2ccccc2)cc1
Show InChI InChI=1S/C21H27NO3/c23-21(24)14-16-22-15-4-8-19-10-12-20(13-11-19)25-17-5-9-18-6-2-1-3-7-18/h1-3,6-7,10-13,22H,4-5,8-9,14-17H2,(H,23,24)
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n/an/an/an/a 2.60E+3n/an/an/an/a



Ono Pharmaceutical Co., Ltd

Curated by ChEMBL


Assay Description
Agonist activity at human S1P1 receptor expressed in CHO cells assessed as intracellular calcium levels


Bioorg Med Chem Lett 21: 1390-3 (2011)


Article DOI: 10.1016/j.bmcl.2011.01.029
BindingDB Entry DOI: 10.7270/Q26973VP
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 1


(Homo sapiens (Human))
BDBM50337592
PNG
(3-(3-(4-(5-phenylpentyloxy)phenyl)propylamino)prop...)
Show SMILES OC(=O)CCNCCCc1ccc(OCCCCCc2ccccc2)cc1
Show InChI InChI=1S/C23H31NO3/c25-23(26)16-18-24-17-7-11-21-12-14-22(15-13-21)27-19-6-2-5-10-20-8-3-1-4-9-20/h1,3-4,8-9,12-15,24H,2,5-7,10-11,16-19H2,(H,25,26)
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n/an/an/an/a 160n/an/an/an/a



Ono Pharmaceutical Co., Ltd

Curated by ChEMBL


Assay Description
Agonist activity at human S1P1 receptor expressed in CHO cells assessed as intracellular calcium levels


Bioorg Med Chem Lett 21: 1390-3 (2011)


Article DOI: 10.1016/j.bmcl.2011.01.029
BindingDB Entry DOI: 10.7270/Q26973VP
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 3


(Homo sapiens (Human))
BDBM50337598
PNG
(CHEMBL1683046 | trans-3-(2-methyl-3-(4-(3-phenylpr...)
Show SMILES C\C(CNCCC(O)=O)=C/c1ccc(OCCCc2ccccc2)cc1
Show InChI InChI=1S/C22H27NO3/c1-18(17-23-14-13-22(24)25)16-20-9-11-21(12-10-20)26-15-5-8-19-6-3-2-4-7-19/h2-4,6-7,9-12,16,23H,5,8,13-15,17H2,1H3,(H,24,25)/b18-16+
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n/an/an/an/a 1.90E+3n/an/an/an/a



Ono Pharmaceutical Co., Ltd

Curated by ChEMBL


Assay Description
Agonist activity at human S1P3 receptor expressed in CHO cells assessed as intracellular calcium levels


Bioorg Med Chem Lett 21: 1390-3 (2011)


Article DOI: 10.1016/j.bmcl.2011.01.029
BindingDB Entry DOI: 10.7270/Q26973VP
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 3


(Homo sapiens (Human))
BDBM50337592
PNG
(3-(3-(4-(5-phenylpentyloxy)phenyl)propylamino)prop...)
Show SMILES OC(=O)CCNCCCc1ccc(OCCCCCc2ccccc2)cc1
Show InChI InChI=1S/C23H31NO3/c25-23(26)16-18-24-17-7-11-21-12-14-22(15-13-21)27-19-6-2-5-10-20-8-3-1-4-9-20/h1,3-4,8-9,12-15,24H,2,5-7,10-11,16-19H2,(H,25,26)
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n/an/an/an/a 4.20E+3n/an/an/an/a



Ono Pharmaceutical Co., Ltd

Curated by ChEMBL


Assay Description
Agonist activity at human S1P3 receptor expressed in CHO cells assessed as intracellular calcium levels


Bioorg Med Chem Lett 21: 1390-3 (2011)


Article DOI: 10.1016/j.bmcl.2011.01.029
BindingDB Entry DOI: 10.7270/Q26973VP
More data for this
Ligand-Target Pair
Sphingosine 1-Phosphate Receptor 2


(Homo sapiens (Human))
BDBM50337592
PNG
(3-(3-(4-(5-phenylpentyloxy)phenyl)propylamino)prop...)
Show SMILES OC(=O)CCNCCCc1ccc(OCCCCCc2ccccc2)cc1
Show InChI InChI=1S/C23H31NO3/c25-23(26)16-18-24-17-7-11-21-12-14-22(15-13-21)27-19-6-2-5-10-20-8-3-1-4-9-20/h1,3-4,8-9,12-15,24H,2,5-7,10-11,16-19H2,(H,25,26)
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n/an/an/an/a>1.00E+4n/an/an/an/a



Ono Pharmaceutical Co., Ltd

Curated by ChEMBL


Assay Description
Agonist activity at human S1P2 receptor expressed in CHO cells assessed as intracellular calcium levels


Bioorg Med Chem Lett 21: 1390-3 (2011)


Article DOI: 10.1016/j.bmcl.2011.01.029
BindingDB Entry DOI: 10.7270/Q26973VP
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 1


(Homo sapiens (Human))
BDBM50337594
PNG
(3-(4-(4-(3-phenylpropoxy)phenyl)piperidin-1-yl)pro...)
Show SMILES OC(=O)CCN1CCC(CC1)c1ccc(OCCCc2ccccc2)cc1
Show InChI InChI=1S/C23H29NO3/c25-23(26)14-17-24-15-12-21(13-16-24)20-8-10-22(11-9-20)27-18-4-7-19-5-2-1-3-6-19/h1-3,5-6,8-11,21H,4,7,12-18H2,(H,25,26)
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n/an/an/an/a 1.60E+3n/an/an/an/a



Ono Pharmaceutical Co., Ltd

Curated by ChEMBL


Assay Description
Agonist activity at human S1P1 receptor expressed in CHO cells assessed as intracellular calcium levels


Bioorg Med Chem Lett 21: 1390-3 (2011)


Article DOI: 10.1016/j.bmcl.2011.01.029
BindingDB Entry DOI: 10.7270/Q26973VP
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 1


(Homo sapiens (Human))
BDBM50337595
PNG
(3-(4-(4-(3-phenylpropoxy)phenyl)-5,6-dihydropyridi...)
Show SMILES OC(=O)CCN1CCC(=CC1)c1ccc(OCCCc2ccccc2)cc1 |c:8|
Show InChI InChI=1S/C23H27NO3/c25-23(26)14-17-24-15-12-21(13-16-24)20-8-10-22(11-9-20)27-18-4-7-19-5-2-1-3-6-19/h1-3,5-6,8-12H,4,7,13-18H2,(H,25,26)
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n/an/an/an/a 45n/an/an/an/a



Ono Pharmaceutical Co., Ltd

Curated by ChEMBL


Assay Description
Agonist activity at human S1P1 receptor expressed in CHO cells assessed as intracellular calcium levels


Bioorg Med Chem Lett 21: 1390-3 (2011)


Article DOI: 10.1016/j.bmcl.2011.01.029
BindingDB Entry DOI: 10.7270/Q26973VP
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 3


(Homo sapiens (Human))
BDBM50337594
PNG
(3-(4-(4-(3-phenylpropoxy)phenyl)piperidin-1-yl)pro...)
Show SMILES OC(=O)CCN1CCC(CC1)c1ccc(OCCCc2ccccc2)cc1
Show InChI InChI=1S/C23H29NO3/c25-23(26)14-17-24-15-12-21(13-16-24)20-8-10-22(11-9-20)27-18-4-7-19-5-2-1-3-6-19/h1-3,5-6,8-11,21H,4,7,12-18H2,(H,25,26)
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n/an/an/an/a>1.00E+4n/an/an/an/a



Ono Pharmaceutical Co., Ltd

Curated by ChEMBL


Assay Description
Agonist activity at human S1P3 receptor expressed in CHO cells assessed as intracellular calcium levels


Bioorg Med Chem Lett 21: 1390-3 (2011)


Article DOI: 10.1016/j.bmcl.2011.01.029
BindingDB Entry DOI: 10.7270/Q26973VP
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 3


(Homo sapiens (Human))
BDBM50337597
PNG
(CHEMBL1683047 | trans-3-(3-(4-(3-phenylpropoxy)phe...)
Show SMILES C\C(=C/CNCCC(O)=O)c1ccc(OCCCc2ccccc2)cc1
Show InChI InChI=1S/C22H27NO3/c1-18(13-15-23-16-14-22(24)25)20-9-11-21(12-10-20)26-17-5-8-19-6-3-2-4-7-19/h2-4,6-7,9-13,23H,5,8,14-17H2,1H3,(H,24,25)/b18-13+
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n/an/an/an/a>1.00E+4n/an/an/an/a



Ono Pharmaceutical Co., Ltd

Curated by ChEMBL


Assay Description
Agonist activity at human S1P3 receptor expressed in CHO cells assessed as intracellular calcium levels


Bioorg Med Chem Lett 21: 1390-3 (2011)


Article DOI: 10.1016/j.bmcl.2011.01.029
BindingDB Entry DOI: 10.7270/Q26973VP
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 3


(Homo sapiens (Human))
BDBM50337599
PNG
((E/Z)-3-(3-(4-(3-phenylpropoxy)phenyl)allylamino)p...)
Show SMILES OC(=O)CCNC\C=C\c1ccc(OCCCc2ccccc2)cc1
Show InChI InChI=1S/C21H25NO3/c23-21(24)14-16-22-15-4-8-19-10-12-20(13-11-19)25-17-5-9-18-6-2-1-3-7-18/h1-4,6-8,10-13,22H,5,9,14-17H2,(H,23,24)/b8-4+
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n/an/an/an/a 3.30E+3n/an/an/an/a



Ono Pharmaceutical Co., Ltd

Curated by ChEMBL


Assay Description
Agonist activity at human S1P3 receptor expressed in CHO cells assessed as intracellular calcium levels


Bioorg Med Chem Lett 21: 1390-3 (2011)


Article DOI: 10.1016/j.bmcl.2011.01.029
BindingDB Entry DOI: 10.7270/Q26973VP
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 3


(Homo sapiens (Human))
BDBM50337590
PNG
(3-(3-(4-(4-phenylbutoxy)phenyl)propylamino)propano...)
Show SMILES OC(=O)CCNCCCc1ccc(OCCCCc2ccccc2)cc1
Show InChI InChI=1S/C22H29NO3/c24-22(25)15-17-23-16-6-10-20-11-13-21(14-12-20)26-18-5-4-9-19-7-2-1-3-8-19/h1-3,7-8,11-14,23H,4-6,9-10,15-18H2,(H,24,25)
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n/an/an/an/a>1.00E+4n/an/an/an/a



Ono Pharmaceutical Co., Ltd

Curated by ChEMBL


Assay Description
Agonist activity at human S1P3 receptor expressed in CHO cells assessed as intracellular calcium levels


Bioorg Med Chem Lett 21: 1390-3 (2011)


Article DOI: 10.1016/j.bmcl.2011.01.029
BindingDB Entry DOI: 10.7270/Q26973VP
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 3


(Homo sapiens (Human))
BDBM50337596
PNG
(CHEMBL1683048 | cis-3-(3-(4-(3-phenylpropoxy)pheny...)
Show SMILES C\C(=C\CNCCC(O)=O)c1ccc(OCCCc2ccccc2)cc1
Show InChI InChI=1S/C22H27NO3/c1-18(13-15-23-16-14-22(24)25)20-9-11-21(12-10-20)26-17-5-8-19-6-3-2-4-7-19/h2-4,6-7,9-13,23H,5,8,14-17H2,1H3,(H,24,25)/b18-13-
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n/an/an/an/a>1.00E+4n/an/an/an/a



Ono Pharmaceutical Co., Ltd

Curated by ChEMBL


Assay Description
Agonist activity at human S1P3 receptor expressed in CHO cells assessed as intracellular calcium levels


Bioorg Med Chem Lett 21: 1390-3 (2011)


Article DOI: 10.1016/j.bmcl.2011.01.029
BindingDB Entry DOI: 10.7270/Q26973VP
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 3


(Homo sapiens (Human))
BDBM50337591
PNG
(3-(3-(4-(3-phenylpropoxy)phenyl)propylamino)propan...)
Show SMILES OC(=O)CCNCCCc1ccc(OCCCc2ccccc2)cc1
Show InChI InChI=1S/C21H27NO3/c23-21(24)14-16-22-15-4-8-19-10-12-20(13-11-19)25-17-5-9-18-6-2-1-3-7-18/h1-3,6-7,10-13,22H,4-5,8-9,14-17H2,(H,23,24)
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n/an/an/an/a 9.00E+3n/an/an/an/a



Ono Pharmaceutical Co., Ltd

Curated by ChEMBL


Assay Description
Agonist activity at human S1P3 receptor expressed in CHO cells assessed as intracellular calcium levels


Bioorg Med Chem Lett 21: 1390-3 (2011)


Article DOI: 10.1016/j.bmcl.2011.01.029
BindingDB Entry DOI: 10.7270/Q26973VP
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 1


(Homo sapiens (Human))
BDBM50337599
PNG
((E/Z)-3-(3-(4-(3-phenylpropoxy)phenyl)allylamino)p...)
Show SMILES OC(=O)CCNC\C=C\c1ccc(OCCCc2ccccc2)cc1
Show InChI InChI=1S/C21H25NO3/c23-21(24)14-16-22-15-4-8-19-10-12-20(13-11-19)25-17-5-9-18-6-2-1-3-7-18/h1-4,6-8,10-13,22H,5,9,14-17H2,(H,23,24)/b8-4+
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n/an/an/an/a 70n/an/an/an/a



Ono Pharmaceutical Co., Ltd

Curated by ChEMBL


Assay Description
Agonist activity at human S1P1 receptor expressed in CHO cells assessed as intracellular calcium levels


Bioorg Med Chem Lett 21: 1390-3 (2011)


Article DOI: 10.1016/j.bmcl.2011.01.029
BindingDB Entry DOI: 10.7270/Q26973VP
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 3


(Homo sapiens (Human))
BDBM50337589
PNG
(3-(3-(4-(6-phenylhexyloxy)phenyl)propylamino)propa...)
Show SMILES OC(=O)CCNCCCc1ccc(OCCCCCCc2ccccc2)cc1
Show InChI InChI=1S/C24H33NO3/c26-24(27)17-19-25-18-8-12-22-13-15-23(16-14-22)28-20-7-2-1-4-9-21-10-5-3-6-11-21/h3,5-6,10-11,13-16,25H,1-2,4,7-9,12,17-20H2,(H,26,27)
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n/an/an/an/a>1.00E+4n/an/an/an/a



Ono Pharmaceutical Co., Ltd

Curated by ChEMBL


Assay Description
Agonist activity at human S1P3 receptor expressed in CHO cells assessed as intracellular calcium levels


Bioorg Med Chem Lett 21: 1390-3 (2011)


Article DOI: 10.1016/j.bmcl.2011.01.029
BindingDB Entry DOI: 10.7270/Q26973VP
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 1


(Homo sapiens (Human))
BDBM50337593
PNG
(CHEMBL1683051 | trans-3-(3-(4-(3-phenylpropoxy)ben...)
Show SMILES OC(=O)CCN1CCC\C(C1)=C/c1ccc(OCCCc2ccccc2)cc1
Show InChI InChI=1S/C24H29NO3/c26-24(27)14-16-25-15-4-8-22(19-25)18-21-10-12-23(13-11-21)28-17-5-9-20-6-2-1-3-7-20/h1-3,6-7,10-13,18H,4-5,8-9,14-17,19H2,(H,26,27)/b22-18+
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n/an/an/an/a 1.50E+3n/an/an/an/a



Ono Pharmaceutical Co., Ltd

Curated by ChEMBL


Assay Description
Agonist activity at human S1P1 receptor expressed in CHO cells assessed as intracellular calcium levels


Bioorg Med Chem Lett 21: 1390-3 (2011)


Article DOI: 10.1016/j.bmcl.2011.01.029
BindingDB Entry DOI: 10.7270/Q26973VP
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 1


(Homo sapiens (Human))
BDBM50337598
PNG
(CHEMBL1683046 | trans-3-(2-methyl-3-(4-(3-phenylpr...)
Show SMILES C\C(CNCCC(O)=O)=C/c1ccc(OCCCc2ccccc2)cc1
Show InChI InChI=1S/C22H27NO3/c1-18(17-23-14-13-22(24)25)16-20-9-11-21(12-10-20)26-15-5-8-19-6-3-2-4-7-19/h2-4,6-7,9-12,16,23H,5,8,13-15,17H2,1H3,(H,24,25)/b18-16+
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n/an/an/an/a 33n/an/an/an/a



Ono Pharmaceutical Co., Ltd

Curated by ChEMBL


Assay Description
Agonist activity at human S1P1 receptor expressed in CHO cells assessed as intracellular calcium levels


Bioorg Med Chem Lett 21: 1390-3 (2011)


Article DOI: 10.1016/j.bmcl.2011.01.029
BindingDB Entry DOI: 10.7270/Q26973VP
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 5


(Homo sapiens (Human))
BDBM50337592
PNG
(3-(3-(4-(5-phenylpentyloxy)phenyl)propylamino)prop...)
Show SMILES OC(=O)CCNCCCc1ccc(OCCCCCc2ccccc2)cc1
Show InChI InChI=1S/C23H31NO3/c25-23(26)16-18-24-17-7-11-21-12-14-22(15-13-21)27-19-6-2-5-10-20-8-3-1-4-9-20/h1,3-4,8-9,12-15,24H,2,5-7,10-11,16-19H2,(H,25,26)
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n/an/an/an/a 170n/an/an/an/a



Ono Pharmaceutical Co., Ltd

Curated by ChEMBL


Assay Description
Agonist activity at human S1P5 receptor expressed in CHO cells assessed as intracellular calcium levels


Bioorg Med Chem Lett 21: 1390-3 (2011)


Article DOI: 10.1016/j.bmcl.2011.01.029
BindingDB Entry DOI: 10.7270/Q26973VP
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 3


(Homo sapiens (Human))
BDBM50337593
PNG
(CHEMBL1683051 | trans-3-(3-(4-(3-phenylpropoxy)ben...)
Show SMILES OC(=O)CCN1CCC\C(C1)=C/c1ccc(OCCCc2ccccc2)cc1
Show InChI InChI=1S/C24H29NO3/c26-24(27)14-16-25-15-4-8-22(19-25)18-21-10-12-23(13-11-21)28-17-5-9-20-6-2-1-3-7-20/h1-3,6-7,10-13,18H,4-5,8-9,14-17,19H2,(H,26,27)/b22-18+
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n/an/an/an/a>1.00E+4n/an/an/an/a



Ono Pharmaceutical Co., Ltd

Curated by ChEMBL


Assay Description
Agonist activity at human S1P3 receptor expressed in CHO cells assessed as intracellular calcium levels


Bioorg Med Chem Lett 21: 1390-3 (2011)


Article DOI: 10.1016/j.bmcl.2011.01.029
BindingDB Entry DOI: 10.7270/Q26973VP
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 3


(Homo sapiens (Human))
BDBM50337595
PNG
(3-(4-(4-(3-phenylpropoxy)phenyl)-5,6-dihydropyridi...)
Show SMILES OC(=O)CCN1CCC(=CC1)c1ccc(OCCCc2ccccc2)cc1 |c:8|
Show InChI InChI=1S/C23H27NO3/c25-23(26)14-17-24-15-12-21(13-16-24)20-8-10-22(11-9-20)27-18-4-7-19-5-2-1-3-6-19/h1-3,5-6,8-12H,4,7,13-18H2,(H,25,26)
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n/an/an/an/a 1.20E+3n/an/an/an/a



Ono Pharmaceutical Co., Ltd

Curated by ChEMBL


Assay Description
Agonist activity at human S1P3 receptor expressed in CHO cells assessed as intracellular calcium levels


Bioorg Med Chem Lett 21: 1390-3 (2011)


Article DOI: 10.1016/j.bmcl.2011.01.029
BindingDB Entry DOI: 10.7270/Q26973VP
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 1


(Homo sapiens (Human))
BDBM50337596
PNG
(CHEMBL1683048 | cis-3-(3-(4-(3-phenylpropoxy)pheny...)
Show SMILES C\C(=C\CNCCC(O)=O)c1ccc(OCCCc2ccccc2)cc1
Show InChI InChI=1S/C22H27NO3/c1-18(13-15-23-16-14-22(24)25)20-9-11-21(12-10-20)26-17-5-8-19-6-3-2-4-7-19/h2-4,6-7,9-13,23H,5,8,14-17H2,1H3,(H,24,25)/b18-13-
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n/an/an/an/a 930n/an/an/an/a



Ono Pharmaceutical Co., Ltd

Curated by ChEMBL


Assay Description
Agonist activity at human S1P1 receptor expressed in CHO cells assessed as intracellular calcium levels


Bioorg Med Chem Lett 21: 1390-3 (2011)


Article DOI: 10.1016/j.bmcl.2011.01.029
BindingDB Entry DOI: 10.7270/Q26973VP
More data for this
Ligand-Target Pair
Sphingosine 1-phosphate receptor 1


(Homo sapiens (Human))
BDBM50337589
PNG
(3-(3-(4-(6-phenylhexyloxy)phenyl)propylamino)propa...)
Show SMILES OC(=O)CCNCCCc1ccc(OCCCCCCc2ccccc2)cc1
Show InChI InChI=1S/C24H33NO3/c26-24(27)17-19-25-18-8-12-22-13-15-23(16-14-22)28-20-7-2-1-4-9-21-10-5-3-6-11-21/h3,5-6,10-11,13-16,25H,1-2,4,7-9,12,17-20H2,(H,26,27)
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n/an/an/an/a 2.70E+3n/an/an/an/a



Ono Pharmaceutical Co., Ltd

Curated by ChEMBL


Assay Description
Agonist activity at human S1P1 receptor expressed in CHO cells assessed as intracellular calcium levels


Bioorg Med Chem Lett 21: 1390-3 (2011)


Article DOI: 10.1016/j.bmcl.2011.01.029
BindingDB Entry DOI: 10.7270/Q26973VP
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%