Found 60 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50392514
(CHEMBL2152167)Show SMILES FC(F)C(F)(F)Oc1cc(F)cc(c1)[C@](Cc1ccccc1)(NC(=O)N[C@@H]1CCC(F)(F)C1)c1ccc(Cl)cn1 |r| Show InChI InChI=1S/C27H23ClF7N3O2/c28-18-6-7-22(36-15-18)26(13-16-4-2-1-3-5-16,38-24(39)37-20-8-9-25(32,33)14-20)17-10-19(29)12-21(11-17)40-27(34,35)23(30)31/h1-7,10-12,15,20,23H,8-9,13-14H2,(H2,37,38,39)/t20-,26+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CETP using [3H]cholesterol ester/HDL as substrate by scintillation proximity assay |
Bioorg Med Chem Lett 22: 6503-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.011
BindingDB Entry DOI: 10.7270/Q2XP761G |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50392527
(CHEMBL2152180)Show SMILES FC(F)C(F)(F)Oc1cc(F)cc(c1)[C@](Cc1ccccc1)(NC(=O)NCCC(F)(F)F)c1ccc(Cl)cn1 |r| Show InChI InChI=1S/C25H20ClF8N3O2/c26-17-6-7-20(36-14-17)23(13-15-4-2-1-3-5-15,37-22(38)35-9-8-24(30,31)32)16-10-18(27)12-19(11-16)39-25(33,34)21(28)29/h1-7,10-12,14,21H,8-9,13H2,(H2,35,37,38)/t23-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CETP using [3H]cholesterol ester/HDL as substrate by scintillation proximity assay |
Bioorg Med Chem Lett 22: 6503-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.011
BindingDB Entry DOI: 10.7270/Q2XP761G |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50392530
(CHEMBL2152183)Show SMILES FC(F)C(F)(F)Oc1cc(F)cc(c1)[C@](Cc1ccccc1)(NC(=O)NCC(F)(F)F)c1ccc(Cl)cn1 |r| Show InChI InChI=1S/C24H18ClF8N3O2/c25-16-6-7-19(34-12-16)22(11-14-4-2-1-3-5-14,36-21(37)35-13-23(29,30)31)15-8-17(26)10-18(9-15)38-24(32,33)20(27)28/h1-10,12,20H,11,13H2,(H2,35,36,37)/t22-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CETP using [3H]cholesterol ester/HDL as substrate by scintillation proximity assay |
Bioorg Med Chem Lett 22: 6503-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.011
BindingDB Entry DOI: 10.7270/Q2XP761G |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50392513
(CHEMBL2152166)Show SMILES FC(F)C(F)(F)Oc1cc(F)cc(c1)[C@](Cc1ccccc1)(NC(=O)NC1CCC(F)(F)C1)c1ccc(Cl)cn1 |r| Show InChI InChI=1S/C27H23ClF7N3O2/c28-18-6-7-22(36-15-18)26(13-16-4-2-1-3-5-16,38-24(39)37-20-8-9-25(32,33)14-20)17-10-19(29)12-21(11-17)40-27(34,35)23(30)31/h1-7,10-12,15,20,23H,8-9,13-14H2,(H2,37,38,39)/t20?,26-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CETP using [3H]cholesterol ester/HDL as substrate by scintillation proximity assay |
Bioorg Med Chem Lett 22: 6503-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.011
BindingDB Entry DOI: 10.7270/Q2XP761G |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50392512
(CHEMBL2152165)Show SMILES FC(F)C(F)(F)Oc1cc(F)cc(c1)[C@](Cc1ccccc1)(NC(=O)NC1CCCC1)c1ccc(Cl)cn1 |r| Show InChI InChI=1S/C27H25ClF5N3O2/c28-19-10-11-23(34-16-19)26(15-17-6-2-1-3-7-17,36-25(37)35-21-8-4-5-9-21)18-12-20(29)14-22(13-18)38-27(32,33)24(30)31/h1-3,6-7,10-14,16,21,24H,4-5,8-9,15H2,(H2,35,36,37)/t26-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CETP using [3H]cholesterol ester/HDL as substrate by scintillation proximity assay |
Bioorg Med Chem Lett 22: 6503-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.011
BindingDB Entry DOI: 10.7270/Q2XP761G |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50392528
(CHEMBL2152181)Show SMILES FC(F)C(F)(F)Oc1cc(F)cc(c1)[C@](Cc1ccccc1)(NC(=O)NCC(F)(F)C(F)(F)F)c1ccc(Cl)cn1 |r| Show InChI InChI=1S/C25H18ClF10N3O2/c26-16-6-7-19(37-12-16)22(11-14-4-2-1-3-5-14,39-21(40)38-13-23(30,31)25(34,35)36)15-8-17(27)10-18(9-15)41-24(32,33)20(28)29/h1-10,12,20H,11,13H2,(H2,38,39,40)/t22-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CETP using [3H]cholesterol ester/HDL as substrate by scintillation proximity assay |
Bioorg Med Chem Lett 22: 6503-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.011
BindingDB Entry DOI: 10.7270/Q2XP761G |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50392504
(CHEMBL2152158)Show SMILES Fc1cc(cc(c1)[C@](Cc1ccccc1)(NC(=O)NC1CCC(F)(F)C1)c1ccc(Cl)cn1)C(F)(F)F |r| Show InChI InChI=1S/C26H22ClF6N3O/c27-19-6-7-22(34-15-19)25(13-16-4-2-1-3-5-16,17-10-18(26(31,32)33)12-20(28)11-17)36-23(37)35-21-8-9-24(29,30)14-21/h1-7,10-12,15,21H,8-9,13-14H2,(H2,35,36,37)/t21?,25-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CETP using [3H]cholesterol ester/HDL as substrate by scintillation proximity assay |
Bioorg Med Chem Lett 22: 6503-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.011
BindingDB Entry DOI: 10.7270/Q2XP761G |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50392515
(CHEMBL2152168)Show SMILES FC(F)C(F)(F)Oc1cc(F)cc(c1)[C@](Cc1ccccc1)(NC(=O)N[C@H]1CCC(F)(F)C1)c1ccc(Cl)cn1 |r| Show InChI InChI=1S/C27H23ClF7N3O2/c28-18-6-7-22(36-15-18)26(13-16-4-2-1-3-5-16,38-24(39)37-20-8-9-25(32,33)14-20)17-10-19(29)12-21(11-17)40-27(34,35)23(30)31/h1-7,10-12,15,20,23H,8-9,13-14H2,(H2,37,38,39)/t20-,26-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CETP using [3H]cholesterol ester/HDL as substrate by scintillation proximity assay |
Bioorg Med Chem Lett 22: 6503-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.011
BindingDB Entry DOI: 10.7270/Q2XP761G |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50392517
(CHEMBL2152170)Show SMILES FC(F)C(F)(F)Oc1cc(F)cc(c1)[C@](Cc1ccccc1)(NC(=O)NC1CC(F)(F)C1)c1ccc(Cl)cn1 |r| Show InChI InChI=1S/C26H21ClF7N3O2/c27-17-6-7-21(35-14-17)25(11-15-4-2-1-3-5-15,37-23(38)36-19-12-24(31,32)13-19)16-8-18(28)10-20(9-16)39-26(33,34)22(29)30/h1-10,14,19,22H,11-13H2,(H2,36,37,38)/t25-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CETP using [3H]cholesterol ester/HDL as substrate by scintillation proximity assay |
Bioorg Med Chem Lett 22: 6503-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.011
BindingDB Entry DOI: 10.7270/Q2XP761G |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50392526
(CHEMBL2152179)Show SMILES CCCNC(=O)N[C@@](Cc1ccccc1)(c1cc(F)cc(OC(F)(F)C(F)F)c1)c1ccc(Cl)cn1 |r| Show InChI InChI=1S/C25H23ClF5N3O2/c1-2-10-32-23(35)34-24(14-16-6-4-3-5-7-16,21-9-8-18(26)15-33-21)17-11-19(27)13-20(12-17)36-25(30,31)22(28)29/h3-9,11-13,15,22H,2,10,14H2,1H3,(H2,32,34,35)/t24-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CETP using [3H]cholesterol ester/HDL as substrate by scintillation proximity assay |
Bioorg Med Chem Lett 22: 6503-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.011
BindingDB Entry DOI: 10.7270/Q2XP761G |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50392522
(CHEMBL2152175)Show SMILES FC(F)C(F)(F)Oc1cc(F)cc(c1)[C@](Cc1ccccc1)(NC(=O)N1CC(F)(F)C(F)(F)C1)c1ccc(Cl)cn1 |r| Show InChI InChI=1S/C26H19ClF9N3O2/c27-17-6-7-20(37-12-17)23(11-15-4-2-1-3-5-15,38-22(40)39-13-24(31,32)25(33,34)14-39)16-8-18(28)10-19(9-16)41-26(35,36)21(29)30/h1-10,12,21H,11,13-14H2,(H,38,40)/t23-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CETP using [3H]cholesterol ester/HDL as substrate by scintillation proximity assay |
Bioorg Med Chem Lett 22: 6503-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.011
BindingDB Entry DOI: 10.7270/Q2XP761G |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50392516
(CHEMBL2152169)Show SMILES FC(F)C(F)(F)Oc1cc(F)cc(c1)[C@](Cc1ccccc1)(NC(=O)NC1CC1(F)F)c1ccc(Cl)cn1 |r| Show InChI InChI=1S/C25H19ClF7N3O2/c26-16-6-7-19(34-13-16)23(11-14-4-2-1-3-5-14,36-22(37)35-20-12-24(20,30)31)15-8-17(27)10-18(9-15)38-25(32,33)21(28)29/h1-10,13,20-21H,11-12H2,(H2,35,36,37)/t20?,23-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CETP using [3H]cholesterol ester/HDL as substrate by scintillation proximity assay |
Bioorg Med Chem Lett 22: 6503-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.011
BindingDB Entry DOI: 10.7270/Q2XP761G |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50392507
(CHEMBL2152162)Show SMILES Fc1cc(cc(c1)[C@](Cc1ccccc1)(NC(=O)NC1CCCCC1(F)F)c1ccc(Cl)cn1)C(F)(F)F |r| Show InChI InChI=1S/C27H24ClF6N3O/c28-20-9-10-22(35-16-20)25(15-17-6-2-1-3-7-17,18-12-19(27(32,33)34)14-21(29)13-18)37-24(38)36-23-8-4-5-11-26(23,30)31/h1-3,6-7,9-10,12-14,16,23H,4-5,8,11,15H2,(H2,36,37,38)/t23?,25-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CETP using [3H]cholesterol ester/HDL as substrate by scintillation proximity assay |
Bioorg Med Chem Lett 22: 6503-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.011
BindingDB Entry DOI: 10.7270/Q2XP761G |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50392499
(CHEMBL2152152)Show SMILES Fc1cc(cc(c1)[C@](Cc1ccccc1)(NC(=O)NC1CCCC1)c1ccc(Cl)cn1)C(F)(F)F |r| Show InChI InChI=1S/C26H24ClF4N3O/c27-20-10-11-23(32-16-20)25(15-17-6-2-1-3-7-17,34-24(35)33-22-8-4-5-9-22)18-12-19(26(29,30)31)14-21(28)13-18/h1-3,6-7,10-14,16,22H,4-5,8-9,15H2,(H2,33,34,35)/t25-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CETP using [3H]cholesterol ester/HDL as substrate by scintillation proximity assay |
Bioorg Med Chem Lett 22: 6503-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.011
BindingDB Entry DOI: 10.7270/Q2XP761G |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50392529
(CHEMBL2152182)Show SMILES CCNC(=O)N[C@@](Cc1ccccc1)(c1cc(F)cc(OC(F)(F)C(F)F)c1)c1ccc(Cl)cn1 |r| Show InChI InChI=1S/C24H21ClF5N3O2/c1-2-31-22(34)33-23(13-15-6-4-3-5-7-15,20-9-8-17(25)14-32-20)16-10-18(26)12-19(11-16)35-24(29,30)21(27)28/h3-12,14,21H,2,13H2,1H3,(H2,31,33,34)/t23-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 27 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CETP using [3H]cholesterol ester/HDL as substrate by scintillation proximity assay |
Bioorg Med Chem Lett 22: 6503-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.011
BindingDB Entry DOI: 10.7270/Q2XP761G |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50392501
(CHEMBL2152154)Show SMILES Fc1cc(cc(c1)[C@](Cc1ccccc1)(NC(=O)N[C@@H]1CCOC1)c1ccc(Cl)cn1)C(F)(F)F |r| Show InChI InChI=1S/C25H22ClF4N3O2/c26-19-6-7-22(31-14-19)24(13-16-4-2-1-3-5-16,33-23(34)32-21-8-9-35-15-21)17-10-18(25(28,29)30)12-20(27)11-17/h1-7,10-12,14,21H,8-9,13,15H2,(H2,32,33,34)/t21-,24+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CETP using [3H]cholesterol ester/HDL as substrate by scintillation proximity assay |
Bioorg Med Chem Lett 22: 6503-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.011
BindingDB Entry DOI: 10.7270/Q2XP761G |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50392525
(CHEMBL2152178)Show SMILES FC(F)C(F)(F)Oc1cc(F)cc(c1)[C@](Cc1ccccc1)(NC(=O)N1CCC[C@@H]1C(F)(F)F)c1ccc(Cl)cn1 |r| Show InChI InChI=1S/C27H22ClF8N3O2/c28-18-8-9-21(37-15-18)25(14-16-5-2-1-3-6-16,38-24(40)39-10-4-7-22(39)26(32,33)34)17-11-19(29)13-20(12-17)41-27(35,36)23(30)31/h1-3,5-6,8-9,11-13,15,22-23H,4,7,10,14H2,(H,38,40)/t22-,25+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CETP using [3H]cholesterol ester/HDL as substrate by scintillation proximity assay |
Bioorg Med Chem Lett 22: 6503-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.011
BindingDB Entry DOI: 10.7270/Q2XP761G |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50392514
(CHEMBL2152167)Show SMILES FC(F)C(F)(F)Oc1cc(F)cc(c1)[C@](Cc1ccccc1)(NC(=O)N[C@@H]1CCC(F)(F)C1)c1ccc(Cl)cn1 |r| Show InChI InChI=1S/C27H23ClF7N3O2/c28-18-6-7-22(36-15-18)26(13-16-4-2-1-3-5-16,38-24(39)37-20-8-9-25(32,33)14-20)17-10-19(29)12-21(11-17)40-27(34,35)23(30)31/h1-7,10-12,15,20,23H,8-9,13-14H2,(H2,37,38,39)/t20-,26+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 76 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb
Curated by ChEMBL
| Assay Description
Inhibition of CETP in human plasma using [3H]cholesterol ester/HDL as substrate after 10 mins by scintillation counting |
Bioorg Med Chem Lett 22: 6503-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.011
BindingDB Entry DOI: 10.7270/Q2XP761G |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50392506
(CHEMBL2152160)Show SMILES Fc1cc(cc(c1)[C@](Cc1ccccc1)(NC(=O)NC1CCCCC1)c1ccc(Cl)cn1)C(F)(F)F |r| Show InChI InChI=1S/C27H26ClF4N3O/c28-21-11-12-24(33-17-21)26(16-18-7-3-1-4-8-18,35-25(36)34-23-9-5-2-6-10-23)19-13-20(27(30,31)32)15-22(29)14-19/h1,3-4,7-8,11-15,17,23H,2,5-6,9-10,16H2,(H2,34,35,36)/t26-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 90 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CETP using [3H]cholesterol ester/HDL as substrate by scintillation proximity assay |
Bioorg Med Chem Lett 22: 6503-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.011
BindingDB Entry DOI: 10.7270/Q2XP761G |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50392523
(CHEMBL2152176)Show SMILES FC(F)C(F)(F)Oc1cc(F)cc(c1)[C@](Cc1ccccc1)(NC(=O)N1CCC(C1)C(F)(F)F)c1ccc(Cl)cn1 |r| Show InChI InChI=1S/C27H22ClF8N3O2/c28-19-6-7-22(37-14-19)25(13-16-4-2-1-3-5-16,38-24(40)39-9-8-17(15-39)26(32,33)34)18-10-20(29)12-21(11-18)41-27(35,36)23(30)31/h1-7,10-12,14,17,23H,8-9,13,15H2,(H,38,40)/t17?,25-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CETP using [3H]cholesterol ester/HDL as substrate by scintillation proximity assay |
Bioorg Med Chem Lett 22: 6503-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.011
BindingDB Entry DOI: 10.7270/Q2XP761G |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50392509
(CHEMBL2152164)Show SMILES Fc1cc(cc(c1)[C@](Cc1ccccc1)(NC(=O)NC1CCC(F)(F)CC1)c1ccc(Cl)cn1)C(F)(F)F |r| Show InChI InChI=1S/C27H24ClF6N3O/c28-20-6-7-23(35-16-20)26(15-17-4-2-1-3-5-17,18-12-19(27(32,33)34)14-21(29)13-18)37-24(38)36-22-8-10-25(30,31)11-9-22/h1-7,12-14,16,22H,8-11,15H2,(H2,36,37,38)/t26-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CETP using [3H]cholesterol ester/HDL as substrate by scintillation proximity assay |
Bioorg Med Chem Lett 22: 6503-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.011
BindingDB Entry DOI: 10.7270/Q2XP761G |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50392508
(CHEMBL2152163)Show SMILES Fc1cc(cc(c1)[C@](Cc1ccccc1)(NC(=O)NC1CCCC(F)(F)C1)c1ccc(Cl)cn1)C(F)(F)F |r| Show InChI InChI=1S/C27H24ClF6N3O/c28-20-8-9-23(35-16-20)26(14-17-5-2-1-3-6-17,18-11-19(27(32,33)34)13-21(29)12-18)37-24(38)36-22-7-4-10-25(30,31)15-22/h1-3,5-6,8-9,11-13,16,22H,4,7,10,14-15H2,(H2,36,37,38)/t22?,26-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CETP using [3H]cholesterol ester/HDL as substrate by scintillation proximity assay |
Bioorg Med Chem Lett 22: 6503-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.011
BindingDB Entry DOI: 10.7270/Q2XP761G |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50392530
(CHEMBL2152183)Show SMILES FC(F)C(F)(F)Oc1cc(F)cc(c1)[C@](Cc1ccccc1)(NC(=O)NCC(F)(F)F)c1ccc(Cl)cn1 |r| Show InChI InChI=1S/C24H18ClF8N3O2/c25-16-6-7-19(34-12-16)22(11-14-4-2-1-3-5-14,36-21(37)35-13-23(29,30)31)15-8-17(26)10-18(9-15)38-24(32,33)20(27)28/h1-10,12,20H,11,13H2,(H2,35,36,37)/t22-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 170 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb
Curated by ChEMBL
| Assay Description
Inhibition of CETP in human plasma using [3H]cholesterol ester/HDL as substrate after 10 mins by scintillation counting |
Bioorg Med Chem Lett 22: 6503-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.011
BindingDB Entry DOI: 10.7270/Q2XP761G |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50392517
(CHEMBL2152170)Show SMILES FC(F)C(F)(F)Oc1cc(F)cc(c1)[C@](Cc1ccccc1)(NC(=O)NC1CC(F)(F)C1)c1ccc(Cl)cn1 |r| Show InChI InChI=1S/C26H21ClF7N3O2/c27-17-6-7-21(35-14-17)25(11-15-4-2-1-3-5-15,37-23(38)36-19-12-24(31,32)13-19)16-8-18(28)10-20(9-16)39-26(33,34)22(29)30/h1-10,14,19,22H,11-13H2,(H2,36,37,38)/t25-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb
Curated by ChEMBL
| Assay Description
Inhibition of CETP in human plasma using [3H]cholesterol ester/HDL as substrate after 10 mins by scintillation counting |
Bioorg Med Chem Lett 22: 6503-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.011
BindingDB Entry DOI: 10.7270/Q2XP761G |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50392528
(CHEMBL2152181)Show SMILES FC(F)C(F)(F)Oc1cc(F)cc(c1)[C@](Cc1ccccc1)(NC(=O)NCC(F)(F)C(F)(F)F)c1ccc(Cl)cn1 |r| Show InChI InChI=1S/C25H18ClF10N3O2/c26-16-6-7-19(37-12-16)22(11-14-4-2-1-3-5-14,39-21(40)38-13-23(30,31)25(34,35)36)15-8-17(27)10-18(9-15)41-24(32,33)20(28)29/h1-10,12,20H,11,13H2,(H2,38,39,40)/t22-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 220 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb
Curated by ChEMBL
| Assay Description
Inhibition of CETP in human plasma using [3H]cholesterol ester/HDL as substrate after 10 mins by scintillation counting |
Bioorg Med Chem Lett 22: 6503-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.011
BindingDB Entry DOI: 10.7270/Q2XP761G |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50392502
(CHEMBL2152156)Show SMILES Fc1cc(cc(c1)[C@](Cc1ccccc1)(NC(=O)N[C@@H]1CCOC1=O)c1ccc(Cl)cn1)C(F)(F)F |r| Show InChI InChI=1S/C25H20ClF4N3O3/c26-18-6-7-21(31-14-18)24(13-15-4-2-1-3-5-15,33-23(35)32-20-8-9-36-22(20)34)16-10-17(25(28,29)30)12-19(27)11-16/h1-7,10-12,14,20H,8-9,13H2,(H2,32,33,35)/t20-,24+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 270 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CETP using [3H]cholesterol ester/HDL as substrate by scintillation proximity assay |
Bioorg Med Chem Lett 22: 6503-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.011
BindingDB Entry DOI: 10.7270/Q2XP761G |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50392505
(CHEMBL2152159)Show SMILES Fc1cc(cc(c1)[C@@](Cc1ccccc1)(NC(=O)NC1CCC(F)(F)C1)c1ccc(Cl)cn1)C(F)(F)F |r| Show InChI InChI=1S/C26H22ClF6N3O/c27-19-6-7-22(34-15-19)25(13-16-4-2-1-3-5-16,17-10-18(26(31,32)33)12-20(28)11-17)36-23(37)35-21-8-9-24(29,30)14-21/h1-7,10-12,15,21H,8-9,13-14H2,(H2,35,36,37)/t21?,25-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 340 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CETP using [3H]cholesterol ester/HDL as substrate by scintillation proximity assay |
Bioorg Med Chem Lett 22: 6503-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.011
BindingDB Entry DOI: 10.7270/Q2XP761G |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50392519
(CHEMBL2152172)Show SMILES FC(F)C(F)(F)Oc1cc(F)cc(c1)[C@](Cc1ccccc1)(NC(=O)N1CCC(F)(F)C1)c1ccc(Cl)cn1 |r| Show InChI InChI=1S/C26H21ClF7N3O2/c27-18-6-7-21(35-14-18)25(13-16-4-2-1-3-5-16,36-23(38)37-9-8-24(31,32)15-37)17-10-19(28)12-20(11-17)39-26(33,34)22(29)30/h1-7,10-12,14,22H,8-9,13,15H2,(H,36,38)/t25-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 340 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CETP using [3H]cholesterol ester/HDL as substrate by scintillation proximity assay |
Bioorg Med Chem Lett 22: 6503-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.011
BindingDB Entry DOI: 10.7270/Q2XP761G |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50392500
(CHEMBL2152153)Show SMILES Fc1cc(cc(c1)[C@@](Cc1ccccc1)(NC(=O)NC1CCCC1)c1ccc(Cl)cn1)C(F)(F)F |r| Show InChI InChI=1S/C26H24ClF4N3O/c27-20-10-11-23(32-16-20)25(15-17-6-2-1-3-7-17,34-24(35)33-22-8-4-5-9-22)18-12-19(26(29,30)31)14-21(28)13-18/h1-3,6-7,10-14,16,22H,4-5,8-9,15H2,(H2,33,34,35)/t25-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 480 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CETP using [3H]cholesterol ester/HDL as substrate by scintillation proximity assay |
Bioorg Med Chem Lett 22: 6503-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.011
BindingDB Entry DOI: 10.7270/Q2XP761G |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50392513
(CHEMBL2152166)Show SMILES FC(F)C(F)(F)Oc1cc(F)cc(c1)[C@](Cc1ccccc1)(NC(=O)NC1CCC(F)(F)C1)c1ccc(Cl)cn1 |r| Show InChI InChI=1S/C27H23ClF7N3O2/c28-18-6-7-22(36-15-18)26(13-16-4-2-1-3-5-16,38-24(39)37-20-8-9-25(32,33)14-20)17-10-19(29)12-21(11-17)40-27(34,35)23(30)31/h1-7,10-12,15,20,23H,8-9,13-14H2,(H2,37,38,39)/t20?,26-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 620 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb
Curated by ChEMBL
| Assay Description
Inhibition of CETP in human plasma using [3H]cholesterol ester/HDL as substrate after 10 mins by scintillation counting |
Bioorg Med Chem Lett 22: 6503-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.011
BindingDB Entry DOI: 10.7270/Q2XP761G |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50392512
(CHEMBL2152165)Show SMILES FC(F)C(F)(F)Oc1cc(F)cc(c1)[C@](Cc1ccccc1)(NC(=O)NC1CCCC1)c1ccc(Cl)cn1 |r| Show InChI InChI=1S/C27H25ClF5N3O2/c28-19-10-11-23(34-16-19)26(15-17-6-2-1-3-7-17,36-25(37)35-21-8-4-5-9-21)18-12-20(29)14-22(13-18)38-27(32,33)24(30)31/h1-3,6-7,10-14,16,21,24H,4-5,8-9,15H2,(H2,35,36,37)/t26-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 630 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb
Curated by ChEMBL
| Assay Description
Inhibition of CETP in human plasma using [3H]cholesterol ester/HDL as substrate after 10 mins by scintillation counting |
Bioorg Med Chem Lett 22: 6503-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.011
BindingDB Entry DOI: 10.7270/Q2XP761G |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50392504
(CHEMBL2152158)Show SMILES Fc1cc(cc(c1)[C@](Cc1ccccc1)(NC(=O)NC1CCC(F)(F)C1)c1ccc(Cl)cn1)C(F)(F)F |r| Show InChI InChI=1S/C26H22ClF6N3O/c27-19-6-7-22(34-15-19)25(13-16-4-2-1-3-5-16,17-10-18(26(31,32)33)12-20(28)11-17)36-23(37)35-21-8-9-24(29,30)14-21/h1-7,10-12,15,21H,8-9,13-14H2,(H2,35,36,37)/t21?,25-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 670 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb
Curated by ChEMBL
| Assay Description
Inhibition of CETP in human plasma using [3H]cholesterol ester/HDL as substrate after 10 mins by scintillation counting |
Bioorg Med Chem Lett 22: 6503-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.011
BindingDB Entry DOI: 10.7270/Q2XP761G |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50392527
(CHEMBL2152180)Show SMILES FC(F)C(F)(F)Oc1cc(F)cc(c1)[C@](Cc1ccccc1)(NC(=O)NCCC(F)(F)F)c1ccc(Cl)cn1 |r| Show InChI InChI=1S/C25H20ClF8N3O2/c26-17-6-7-20(36-14-17)23(13-15-4-2-1-3-5-15,37-22(38)35-9-8-24(30,31)32)16-10-18(27)12-19(11-16)39-25(33,34)21(28)29/h1-7,10-12,14,21H,8-9,13H2,(H2,35,37,38)/t23-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 690 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb
Curated by ChEMBL
| Assay Description
Inhibition of CETP in human plasma using [3H]cholesterol ester/HDL as substrate after 10 mins by scintillation counting |
Bioorg Med Chem Lett 22: 6503-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.011
BindingDB Entry DOI: 10.7270/Q2XP761G |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50392521
(CHEMBL2152174)Show SMILES FC(F)C(F)(F)Oc1cc(F)cc(c1)[C@](Cc1ccccc1)(NC(=O)N1CC[C@@H](F)C1)c1ccc(Cl)cn1 |r| Show InChI InChI=1S/C26H22ClF6N3O2/c27-18-6-7-22(34-14-18)25(13-16-4-2-1-3-5-16,35-24(37)36-9-8-19(28)15-36)17-10-20(29)12-21(11-17)38-26(32,33)23(30)31/h1-7,10-12,14,19,23H,8-9,13,15H2,(H,35,37)/t19-,25+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 970 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CETP using [3H]cholesterol ester/HDL as substrate by scintillation proximity assay |
Bioorg Med Chem Lett 22: 6503-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.011
BindingDB Entry DOI: 10.7270/Q2XP761G |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50392518
(CHEMBL2152171)Show SMILES FC(F)C(F)(F)Oc1cc(F)cc(c1)[C@](Cc1ccccc1)(NC(=O)N1CCCC1)c1ccc(Cl)cn1 |r| Show InChI InChI=1S/C26H23ClF5N3O2/c27-19-8-9-22(33-16-19)25(15-17-6-2-1-3-7-17,34-24(36)35-10-4-5-11-35)18-12-20(28)14-21(13-18)37-26(31,32)23(29)30/h1-3,6-9,12-14,16,23H,4-5,10-11,15H2,(H,34,36)/t25-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.27E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CETP using [3H]cholesterol ester/HDL as substrate by scintillation proximity assay |
Bioorg Med Chem Lett 22: 6503-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.011
BindingDB Entry DOI: 10.7270/Q2XP761G |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50392499
(CHEMBL2152152)Show SMILES Fc1cc(cc(c1)[C@](Cc1ccccc1)(NC(=O)NC1CCCC1)c1ccc(Cl)cn1)C(F)(F)F |r| Show InChI InChI=1S/C26H24ClF4N3O/c27-20-10-11-23(32-16-20)25(15-17-6-2-1-3-7-17,34-24(35)33-22-8-4-5-9-22)18-12-19(26(29,30)31)14-21(28)13-18/h1-3,6-7,10-14,16,22H,4-5,8-9,15H2,(H2,33,34,35)/t25-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.57E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb
Curated by ChEMBL
| Assay Description
Inhibition of CETP in human plasma using [3H]cholesterol ester/HDL as substrate after 10 mins by scintillation counting |
Bioorg Med Chem Lett 22: 6503-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.011
BindingDB Entry DOI: 10.7270/Q2XP761G |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50392516
(CHEMBL2152169)Show SMILES FC(F)C(F)(F)Oc1cc(F)cc(c1)[C@](Cc1ccccc1)(NC(=O)NC1CC1(F)F)c1ccc(Cl)cn1 |r| Show InChI InChI=1S/C25H19ClF7N3O2/c26-16-6-7-19(34-13-16)23(11-14-4-2-1-3-5-14,36-22(37)35-20-12-24(20,30)31)15-8-17(27)10-18(9-15)38-25(32,33)21(28)29/h1-10,13,20-21H,11-12H2,(H2,35,36,37)/t20?,23-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.65E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb
Curated by ChEMBL
| Assay Description
Inhibition of CETP in human plasma using [3H]cholesterol ester/HDL as substrate after 10 mins by scintillation counting |
Bioorg Med Chem Lett 22: 6503-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.011
BindingDB Entry DOI: 10.7270/Q2XP761G |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50392522
(CHEMBL2152175)Show SMILES FC(F)C(F)(F)Oc1cc(F)cc(c1)[C@](Cc1ccccc1)(NC(=O)N1CC(F)(F)C(F)(F)C1)c1ccc(Cl)cn1 |r| Show InChI InChI=1S/C26H19ClF9N3O2/c27-17-6-7-20(37-12-17)23(11-15-4-2-1-3-5-15,38-22(40)39-13-24(31,32)25(33,34)14-39)16-8-18(28)10-19(9-16)41-26(35,36)21(29)30/h1-10,12,21H,11,13-14H2,(H,38,40)/t23-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.68E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb
Curated by ChEMBL
| Assay Description
Inhibition of CETP in human plasma using [3H]cholesterol ester/HDL as substrate after 10 mins by scintillation counting |
Bioorg Med Chem Lett 22: 6503-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.011
BindingDB Entry DOI: 10.7270/Q2XP761G |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50392526
(CHEMBL2152179)Show SMILES CCCNC(=O)N[C@@](Cc1ccccc1)(c1cc(F)cc(OC(F)(F)C(F)F)c1)c1ccc(Cl)cn1 |r| Show InChI InChI=1S/C25H23ClF5N3O2/c1-2-10-32-23(35)34-24(14-16-6-4-3-5-7-16,21-9-8-18(26)15-33-21)17-11-19(27)13-20(12-17)36-25(30,31)22(28)29/h3-9,11-13,15,22H,2,10,14H2,1H3,(H2,32,34,35)/t24-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.74E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb
Curated by ChEMBL
| Assay Description
Inhibition of CETP in human plasma using [3H]cholesterol ester/HDL as substrate after 10 mins by scintillation counting |
Bioorg Med Chem Lett 22: 6503-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.011
BindingDB Entry DOI: 10.7270/Q2XP761G |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50392515
(CHEMBL2152168)Show SMILES FC(F)C(F)(F)Oc1cc(F)cc(c1)[C@](Cc1ccccc1)(NC(=O)N[C@H]1CCC(F)(F)C1)c1ccc(Cl)cn1 |r| Show InChI InChI=1S/C27H23ClF7N3O2/c28-18-6-7-22(36-15-18)26(13-16-4-2-1-3-5-16,38-24(39)37-20-8-9-25(32,33)14-20)17-10-19(29)12-21(11-17)40-27(34,35)23(30)31/h1-7,10-12,15,20,23H,8-9,13-14H2,(H2,37,38,39)/t20-,26-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.72E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb
Curated by ChEMBL
| Assay Description
Inhibition of CETP in human plasma using [3H]cholesterol ester/HDL as substrate after 10 mins by scintillation counting |
Bioorg Med Chem Lett 22: 6503-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.011
BindingDB Entry DOI: 10.7270/Q2XP761G |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50392520
(CHEMBL2152173)Show SMILES FC(F)C(F)(F)Oc1cc(F)cc(c1)[C@](Cc1ccccc1)(NC(=O)N1CC[C@H](F)C1)c1ccc(Cl)cn1 |r| Show InChI InChI=1S/C26H22ClF6N3O2/c27-18-6-7-22(34-14-18)25(13-16-4-2-1-3-5-16,35-24(37)36-9-8-19(28)15-36)17-10-20(29)12-21(11-17)38-26(32,33)23(30)31/h1-7,10-12,14,19,23H,8-9,13,15H2,(H,35,37)/t19-,25-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CETP using [3H]cholesterol ester/HDL as substrate by scintillation proximity assay |
Bioorg Med Chem Lett 22: 6503-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.011
BindingDB Entry DOI: 10.7270/Q2XP761G |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50392507
(CHEMBL2152162)Show SMILES Fc1cc(cc(c1)[C@](Cc1ccccc1)(NC(=O)NC1CCCCC1(F)F)c1ccc(Cl)cn1)C(F)(F)F |r| Show InChI InChI=1S/C27H24ClF6N3O/c28-20-9-10-22(35-16-20)25(15-17-6-2-1-3-7-17,18-12-19(27(32,33)34)14-21(29)13-18)37-24(38)36-23-8-4-5-11-26(23,30)31/h1-3,6-7,9-10,12-14,16,23H,4-5,8,11,15H2,(H2,36,37,38)/t23?,25-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.23E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb
Curated by ChEMBL
| Assay Description
Inhibition of CETP in human plasma using [3H]cholesterol ester/HDL as substrate after 10 mins by scintillation counting |
Bioorg Med Chem Lett 22: 6503-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.011
BindingDB Entry DOI: 10.7270/Q2XP761G |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50392525
(CHEMBL2152178)Show SMILES FC(F)C(F)(F)Oc1cc(F)cc(c1)[C@](Cc1ccccc1)(NC(=O)N1CCC[C@@H]1C(F)(F)F)c1ccc(Cl)cn1 |r| Show InChI InChI=1S/C27H22ClF8N3O2/c28-18-8-9-21(37-15-18)25(14-16-5-2-1-3-6-16,38-24(40)39-10-4-7-22(39)26(32,33)34)17-11-19(29)13-20(12-17)41-27(35,36)23(30)31/h1-3,5-6,8-9,11-13,15,22-23H,4,7,10,14H2,(H,38,40)/t22-,25+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.63E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb
Curated by ChEMBL
| Assay Description
Inhibition of CETP in human plasma using [3H]cholesterol ester/HDL as substrate after 10 mins by scintillation counting |
Bioorg Med Chem Lett 22: 6503-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.011
BindingDB Entry DOI: 10.7270/Q2XP761G |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50392501
(CHEMBL2152154)Show SMILES Fc1cc(cc(c1)[C@](Cc1ccccc1)(NC(=O)N[C@@H]1CCOC1)c1ccc(Cl)cn1)C(F)(F)F |r| Show InChI InChI=1S/C25H22ClF4N3O2/c26-19-6-7-22(31-14-19)24(13-16-4-2-1-3-5-16,33-23(34)32-21-8-9-35-15-21)17-10-18(25(28,29)30)12-20(27)11-17/h1-7,10-12,14,21H,8-9,13,15H2,(H2,32,33,34)/t21-,24+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.88E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb
Curated by ChEMBL
| Assay Description
Inhibition of CETP in human plasma using [3H]cholesterol ester/HDL as substrate after 10 mins by scintillation counting |
Bioorg Med Chem Lett 22: 6503-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.011
BindingDB Entry DOI: 10.7270/Q2XP761G |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50392529
(CHEMBL2152182)Show SMILES CCNC(=O)N[C@@](Cc1ccccc1)(c1cc(F)cc(OC(F)(F)C(F)F)c1)c1ccc(Cl)cn1 |r| Show InChI InChI=1S/C24H21ClF5N3O2/c1-2-31-22(34)33-23(13-15-6-4-3-5-7-15,20-9-8-17(25)14-32-20)16-10-18(26)12-19(11-16)35-24(29,30)21(27)28/h3-12,14,21H,2,13H2,1H3,(H2,31,33,34)/t23-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7.03E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb
Curated by ChEMBL
| Assay Description
Inhibition of CETP in human plasma using [3H]cholesterol ester/HDL as substrate after 10 mins by scintillation counting |
Bioorg Med Chem Lett 22: 6503-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.011
BindingDB Entry DOI: 10.7270/Q2XP761G |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50392502
(CHEMBL2152156)Show SMILES Fc1cc(cc(c1)[C@](Cc1ccccc1)(NC(=O)N[C@@H]1CCOC1=O)c1ccc(Cl)cn1)C(F)(F)F |r| Show InChI InChI=1S/C25H20ClF4N3O3/c26-18-6-7-21(31-14-18)24(13-15-4-2-1-3-5-15,33-23(35)32-20-8-9-36-22(20)34)16-10-17(25(28,29)30)12-19(27)11-16/h1-7,10-12,14,20H,8-9,13H2,(H2,32,33,35)/t20-,24+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb
Curated by ChEMBL
| Assay Description
Inhibition of CETP in human plasma using [3H]cholesterol ester/HDL as substrate after 10 mins by scintillation counting |
Bioorg Med Chem Lett 22: 6503-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.011
BindingDB Entry DOI: 10.7270/Q2XP761G |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50392523
(CHEMBL2152176)Show SMILES FC(F)C(F)(F)Oc1cc(F)cc(c1)[C@](Cc1ccccc1)(NC(=O)N1CCC(C1)C(F)(F)F)c1ccc(Cl)cn1 |r| Show InChI InChI=1S/C27H22ClF8N3O2/c28-19-6-7-22(37-14-19)25(13-16-4-2-1-3-5-16,38-24(40)39-9-8-17(15-39)26(32,33)34)18-10-20(29)12-21(11-18)41-27(35,36)23(30)31/h1-7,10-12,14,17,23H,8-9,13,15H2,(H,38,40)/t17?,25-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 8.15E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb
Curated by ChEMBL
| Assay Description
Inhibition of CETP in human plasma using [3H]cholesterol ester/HDL as substrate after 10 mins by scintillation counting |
Bioorg Med Chem Lett 22: 6503-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.011
BindingDB Entry DOI: 10.7270/Q2XP761G |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50392506
(CHEMBL2152160)Show SMILES Fc1cc(cc(c1)[C@](Cc1ccccc1)(NC(=O)NC1CCCCC1)c1ccc(Cl)cn1)C(F)(F)F |r| Show InChI InChI=1S/C27H26ClF4N3O/c28-21-11-12-24(33-17-21)26(16-18-7-3-1-4-8-18,35-25(36)34-23-9-5-2-6-10-23)19-13-20(27(30,31)32)15-22(29)14-19/h1,3-4,7-8,11-15,17,23H,2,5-6,9-10,16H2,(H2,34,35,36)/t26-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 8.89E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb
Curated by ChEMBL
| Assay Description
Inhibition of CETP in human plasma using [3H]cholesterol ester/HDL as substrate after 10 mins by scintillation counting |
Bioorg Med Chem Lett 22: 6503-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.011
BindingDB Entry DOI: 10.7270/Q2XP761G |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50392509
(CHEMBL2152164)Show SMILES Fc1cc(cc(c1)[C@](Cc1ccccc1)(NC(=O)NC1CCC(F)(F)CC1)c1ccc(Cl)cn1)C(F)(F)F |r| Show InChI InChI=1S/C27H24ClF6N3O/c28-20-6-7-23(35-16-20)26(15-17-4-2-1-3-5-17,18-12-19(27(32,33)34)14-21(29)13-18)37-24(38)36-22-8-10-25(30,31)11-9-22/h1-7,12-14,16,22H,8-11,15H2,(H2,36,37,38)/t26-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.31E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb
Curated by ChEMBL
| Assay Description
Inhibition of CETP in human plasma using [3H]cholesterol ester/HDL as substrate after 10 mins by scintillation counting |
Bioorg Med Chem Lett 22: 6503-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.011
BindingDB Entry DOI: 10.7270/Q2XP761G |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50392503
(CHEMBL2152157)Show SMILES Fc1cc(cc(c1)[C@@](Cc1ccccc1)(NC(=O)N[C@@H]1CCOC1=O)c1ccc(Cl)cn1)C(F)(F)F |r| Show InChI InChI=1S/C25H20ClF4N3O3/c26-18-6-7-21(31-14-18)24(13-15-4-2-1-3-5-15,33-23(35)32-20-8-9-36-22(20)34)16-10-17(25(28,29)30)12-19(27)11-16/h1-7,10-12,14,20H,8-9,13H2,(H2,32,33,35)/t20-,24-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.45E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CETP using [3H]cholesterol ester/HDL as substrate by scintillation proximity assay |
Bioorg Med Chem Lett 22: 6503-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.011
BindingDB Entry DOI: 10.7270/Q2XP761G |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50392508
(CHEMBL2152163)Show SMILES Fc1cc(cc(c1)[C@](Cc1ccccc1)(NC(=O)NC1CCCC(F)(F)C1)c1ccc(Cl)cn1)C(F)(F)F |r| Show InChI InChI=1S/C27H24ClF6N3O/c28-20-8-9-23(35-16-20)26(14-17-5-2-1-3-6-17,18-11-19(27(32,33)34)13-21(29)12-18)37-24(38)36-22-7-4-10-25(30,31)15-22/h1-3,5-6,8-9,11-13,16,22H,4,7,10,14-15H2,(H2,36,37,38)/t22?,26-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.72E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb
Curated by ChEMBL
| Assay Description
Inhibition of CETP in human plasma using [3H]cholesterol ester/HDL as substrate after 10 mins by scintillation counting |
Bioorg Med Chem Lett 22: 6503-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.011
BindingDB Entry DOI: 10.7270/Q2XP761G |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50392519
(CHEMBL2152172)Show SMILES FC(F)C(F)(F)Oc1cc(F)cc(c1)[C@](Cc1ccccc1)(NC(=O)N1CCC(F)(F)C1)c1ccc(Cl)cn1 |r| Show InChI InChI=1S/C26H21ClF7N3O2/c27-18-6-7-21(35-14-18)25(13-16-4-2-1-3-5-16,36-23(38)37-9-8-24(31,32)15-37)17-10-19(28)12-20(11-17)39-26(33,34)22(29)30/h1-7,10-12,14,22H,8-9,13,15H2,(H,36,38)/t25-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.91E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb
Curated by ChEMBL
| Assay Description
Inhibition of CETP in human plasma using [3H]cholesterol ester/HDL as substrate after 10 mins by scintillation counting |
Bioorg Med Chem Lett 22: 6503-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.011
BindingDB Entry DOI: 10.7270/Q2XP761G |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50392524
(CHEMBL2152177)Show SMILES FC(F)C(F)(F)Oc1cc(F)cc(c1)[C@](Cc1ccccc1)(NC(=O)N1CCC[C@H]1C(F)(F)F)c1ccc(Cl)cn1 |r| Show InChI InChI=1S/C27H22ClF8N3O2/c28-18-8-9-21(37-15-18)25(14-16-5-2-1-3-6-16,38-24(40)39-10-4-7-22(39)26(32,33)34)17-11-19(29)13-20(12-17)41-27(35,36)23(30)31/h1-3,5-6,8-9,11-13,15,22-23H,4,7,10,14H2,(H,38,40)/t22-,25-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant CETP using [3H]cholesterol ester/HDL as substrate by scintillation proximity assay |
Bioorg Med Chem Lett 22: 6503-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.011
BindingDB Entry DOI: 10.7270/Q2XP761G |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50392505
(CHEMBL2152159)Show SMILES Fc1cc(cc(c1)[C@@](Cc1ccccc1)(NC(=O)NC1CCC(F)(F)C1)c1ccc(Cl)cn1)C(F)(F)F |r| Show InChI InChI=1S/C26H22ClF6N3O/c27-19-6-7-22(34-15-19)25(13-16-4-2-1-3-5-16,17-10-18(26(31,32)33)12-20(28)11-17)36-23(37)35-21-8-9-24(29,30)14-21/h1-7,10-12,15,21H,8-9,13-14H2,(H2,35,36,37)/t21?,25-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.28E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb
Curated by ChEMBL
| Assay Description
Inhibition of CETP in human plasma using [3H]cholesterol ester/HDL as substrate after 10 mins by scintillation counting |
Bioorg Med Chem Lett 22: 6503-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.011
BindingDB Entry DOI: 10.7270/Q2XP761G |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50392500
(CHEMBL2152153)Show SMILES Fc1cc(cc(c1)[C@@](Cc1ccccc1)(NC(=O)NC1CCCC1)c1ccc(Cl)cn1)C(F)(F)F |r| Show InChI InChI=1S/C26H24ClF4N3O/c27-20-10-11-23(32-16-20)25(15-17-6-2-1-3-7-17,34-24(35)33-22-8-4-5-9-22)18-12-19(26(29,30)31)14-21(28)13-18/h1-3,6-7,10-14,16,22H,4-5,8-9,15H2,(H2,33,34,35)/t25-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.33E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb
Curated by ChEMBL
| Assay Description
Inhibition of CETP in human plasma using [3H]cholesterol ester/HDL as substrate after 10 mins by scintillation counting |
Bioorg Med Chem Lett 22: 6503-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.011
BindingDB Entry DOI: 10.7270/Q2XP761G |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50392521
(CHEMBL2152174)Show SMILES FC(F)C(F)(F)Oc1cc(F)cc(c1)[C@](Cc1ccccc1)(NC(=O)N1CC[C@@H](F)C1)c1ccc(Cl)cn1 |r| Show InChI InChI=1S/C26H22ClF6N3O2/c27-18-6-7-22(34-14-18)25(13-16-4-2-1-3-5-16,35-24(37)36-9-8-19(28)15-36)17-10-20(29)12-21(11-17)38-26(32,33)23(30)31/h1-7,10-12,14,19,23H,8-9,13,15H2,(H,35,37)/t19-,25+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.13E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb
Curated by ChEMBL
| Assay Description
Inhibition of CETP in human plasma using [3H]cholesterol ester/HDL as substrate after 10 mins by scintillation counting |
Bioorg Med Chem Lett 22: 6503-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.011
BindingDB Entry DOI: 10.7270/Q2XP761G |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50392510
(CHEMBL2152155)Show SMILES Fc1cc(cc(c1)[C@@](Cc1ccccc1)(NC(=O)N[C@@H]1CCOC1)c1ccc(Cl)cn1)C(F)(F)F |r| Show InChI InChI=1S/C25H22ClF4N3O2/c26-19-6-7-22(31-14-19)24(13-16-4-2-1-3-5-16,33-23(34)32-21-8-9-35-15-21)17-10-18(25(28,29)30)12-20(27)11-17/h1-7,10-12,14,21H,8-9,13,15H2,(H2,32,33,34)/t21-,24-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.46E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb
Curated by ChEMBL
| Assay Description
Inhibition of CETP in human plasma using [3H]cholesterol ester/HDL as substrate after 10 mins by scintillation counting |
Bioorg Med Chem Lett 22: 6503-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.011
BindingDB Entry DOI: 10.7270/Q2XP761G |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50392520
(CHEMBL2152173)Show SMILES FC(F)C(F)(F)Oc1cc(F)cc(c1)[C@](Cc1ccccc1)(NC(=O)N1CC[C@H](F)C1)c1ccc(Cl)cn1 |r| Show InChI InChI=1S/C26H22ClF6N3O2/c27-18-6-7-22(34-14-18)25(13-16-4-2-1-3-5-16,35-24(37)36-9-8-19(28)15-36)17-10-20(29)12-21(11-17)38-26(32,33)23(30)31/h1-7,10-12,14,19,23H,8-9,13,15H2,(H,35,37)/t19-,25-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6.66E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb
Curated by ChEMBL
| Assay Description
Inhibition of CETP in human plasma using [3H]cholesterol ester/HDL as substrate after 10 mins by scintillation counting |
Bioorg Med Chem Lett 22: 6503-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.011
BindingDB Entry DOI: 10.7270/Q2XP761G |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50392511
(CHEMBL2152161)Show SMILES Fc1cc(cc(c1)[C@@](Cc1ccccc1)(NC(=O)NC1CCCCC1)c1ccc(Cl)cn1)C(F)(F)F |r| Show InChI InChI=1S/C27H26ClF4N3O/c28-21-11-12-24(33-17-21)26(16-18-7-3-1-4-8-18,35-25(36)34-23-9-5-2-6-10-23)19-13-20(27(30,31)32)15-22(29)14-19/h1,3-4,7-8,11-15,17,23H,2,5-6,9-10,16H2,(H2,34,35,36)/t26-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 9.18E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb
Curated by ChEMBL
| Assay Description
Inhibition of CETP in human plasma using [3H]cholesterol ester/HDL as substrate after 10 mins by scintillation counting |
Bioorg Med Chem Lett 22: 6503-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.011
BindingDB Entry DOI: 10.7270/Q2XP761G |
More data for this
Ligand-Target Pair | |
Cholesteryl ester transfer protein
(Homo sapiens (Human)) | BDBM50392518
(CHEMBL2152171)Show SMILES FC(F)C(F)(F)Oc1cc(F)cc(c1)[C@](Cc1ccccc1)(NC(=O)N1CCCC1)c1ccc(Cl)cn1 |r| Show InChI InChI=1S/C26H23ClF5N3O2/c27-19-8-9-22(33-16-19)25(15-17-6-2-1-3-7-17,34-24(36)35-10-4-5-11-35)18-12-20(28)14-21(13-18)37-26(31,32)23(29)30/h1-3,6-9,12-14,16,23H,4-5,10-11,15H2,(H,34,36)/t25-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 9.25E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb
Curated by ChEMBL
| Assay Description
Inhibition of CETP in human plasma using [3H]cholesterol ester/HDL as substrate after 10 mins by scintillation counting |
Bioorg Med Chem Lett 22: 6503-8 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.011
BindingDB Entry DOI: 10.7270/Q2XP761G |
More data for this
Ligand-Target Pair | |
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