Found 60 hits of Enzyme Inhibition Constant Data Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM10880
(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| 5.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Cagliari
Curated by ChEMBL
| Assay Description Inhibition of human recombinant transmembrane tumor associated carbonic anhydrase-12 incubated for 15 mins prior to testing by stopped-flow CO2 hydra... |
Bioorg Med Chem Lett 24: 1776-9 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.030 BindingDB Entry DOI: 10.7270/Q25D8TC6 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50008327
(CHEMBL3235167)Show SMILES NS(=O)(=O)c1ccc(cc1)N(CC(=O)c1ccccc1)\C=C\C(=O)C(F)(F)F Show InChI InChI=1S/C18H15F3N2O4S/c19-18(20,21)17(25)10-11-23(12-16(24)13-4-2-1-3-5-13)14-6-8-15(9-7-14)28(22,26)27/h1-11H,12H2,(H2,22,26,27)/b11-10+ | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 9.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Cagliari
Curated by ChEMBL
| Assay Description Inhibition of human recombinant transmembrane tumor associated carbonic anhydrase-9 incubated for 15 mins prior to testing by stopped-flow CO2 hydras... |
Bioorg Med Chem Lett 24: 1776-9 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.030 BindingDB Entry DOI: 10.7270/Q25D8TC6 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM10880
(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| DrugBank MMDB PDB Article PubMed
| 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Cagliari
Curated by ChEMBL
| Assay Description Inhibition of human recombinant cytosolic human carbonic anhydrase-2 incubated for 15 mins prior to testing by stopped-flow CO2 hydrase assay |
Bioorg Med Chem Lett 24: 1776-9 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.030 BindingDB Entry DOI: 10.7270/Q25D8TC6 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM50008345
(CHEMBL3235173)Show SMILES NS(=O)(=O)c1ccc(cc1)-n1cc([nH]c1=O)-c1ccccc1 Show InChI InChI=1S/C15H13N3O3S/c16-22(20,21)13-8-6-12(7-9-13)18-10-14(17-15(18)19)11-4-2-1-3-5-11/h1-10H,(H,17,19)(H2,16,20,21) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Cagliari
Curated by ChEMBL
| Assay Description Inhibition of human recombinant transmembrane tumor associated carbonic anhydrase-12 incubated for 15 mins prior to testing by stopped-flow CO2 hydra... |
Bioorg Med Chem Lett 24: 1776-9 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.030 BindingDB Entry DOI: 10.7270/Q25D8TC6 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM50008350
(CHEMBL3235176)Show SMILES NS(=O)(=O)c1ccc(cc1)-n1cc([nH]c1=S)-c1ccc(F)cc1 Show InChI InChI=1S/C15H12FN3O2S2/c16-11-3-1-10(2-4-11)14-9-19(15(22)18-14)12-5-7-13(8-6-12)23(17,20)21/h1-9H,(H,18,22)(H2,17,20,21) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Cagliari
Curated by ChEMBL
| Assay Description Inhibition of human recombinant transmembrane tumor associated carbonic anhydrase-12 incubated for 15 mins prior to testing by stopped-flow CO2 hydra... |
Bioorg Med Chem Lett 24: 1776-9 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.030 BindingDB Entry DOI: 10.7270/Q25D8TC6 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50008349
(CHEMBL3235175)Show SMILES NS(=O)(=O)c1ccc(cc1)-n1cc([nH]c1=S)-c1ccccc1 Show InChI InChI=1S/C15H13N3O2S2/c16-22(19,20)13-8-6-12(7-9-13)18-10-14(17-15(18)21)11-4-2-1-3-5-11/h1-10H,(H,17,21)(H2,16,19,20) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Cagliari
Curated by ChEMBL
| Assay Description Inhibition of human recombinant transmembrane tumor associated carbonic anhydrase-9 incubated for 15 mins prior to testing by stopped-flow CO2 hydras... |
Bioorg Med Chem Lett 24: 1776-9 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.030 BindingDB Entry DOI: 10.7270/Q25D8TC6 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50008334
(CHEMBL3235169)Show SMILES NS(=O)(=O)c1ccc(cc1)N(CC(=O)c1ccc(F)cc1)\C=C\C(=O)C(F)(F)F Show InChI InChI=1S/C18H14F4N2O4S/c19-13-3-1-12(2-4-13)16(25)11-24(10-9-17(26)18(20,21)22)14-5-7-15(8-6-14)29(23,27)28/h1-10H,11H2,(H2,23,27,28)/b10-9+ | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Cagliari
Curated by ChEMBL
| Assay Description Inhibition of human recombinant transmembrane tumor associated carbonic anhydrase-9 incubated for 15 mins prior to testing by stopped-flow CO2 hydras... |
Bioorg Med Chem Lett 24: 1776-9 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.030 BindingDB Entry DOI: 10.7270/Q25D8TC6 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM50008343
(CHEMBL3235172)Show SMILES CCOC(=O)NC(=S)N(CC(=O)c1ccc(Cl)cc1)c1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C18H18ClN3O5S2/c1-2-27-18(24)21-17(28)22(11-16(23)12-3-5-13(19)6-4-12)14-7-9-15(10-8-14)29(20,25)26/h3-10H,2,11H2,1H3,(H2,20,25,26)(H,21,24,28) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 14 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Cagliari
Curated by ChEMBL
| Assay Description Inhibition of human recombinant transmembrane tumor associated carbonic anhydrase-12 incubated for 15 mins prior to testing by stopped-flow CO2 hydra... |
Bioorg Med Chem Lett 24: 1776-9 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.030 BindingDB Entry DOI: 10.7270/Q25D8TC6 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50008332
(CHEMBL3235168)Show SMILES NS(=O)(=O)c1ccc(cc1)N(CC(=O)c1ccc(Cl)cc1)\C=C\C(=O)C(F)(F)F Show InChI InChI=1S/C18H14ClF3N2O4S/c19-13-3-1-12(2-4-13)16(25)11-24(10-9-17(26)18(20,21)22)14-5-7-15(8-6-14)29(23,27)28/h1-10H,11H2,(H2,23,27,28)/b10-9+ | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 17 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Cagliari
Curated by ChEMBL
| Assay Description Inhibition of human recombinant transmembrane tumor associated carbonic anhydrase-9 incubated for 15 mins prior to testing by stopped-flow CO2 hydras... |
Bioorg Med Chem Lett 24: 1776-9 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.030 BindingDB Entry DOI: 10.7270/Q25D8TC6 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50008338
(CHEMBL3235170)Show SMILES Cc1ccc(cc1)C(=O)CN(\C=C\C(=O)C(F)(F)F)c1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C19H17F3N2O4S/c1-13-2-4-14(5-3-13)17(25)12-24(11-10-18(26)19(20,21)22)15-6-8-16(9-7-15)29(23,27)28/h2-11H,12H2,1H3,(H2,23,27,28)/b11-10+ | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 18 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Cagliari
Curated by ChEMBL
| Assay Description Inhibition of human recombinant transmembrane tumor associated carbonic anhydrase-9 incubated for 15 mins prior to testing by stopped-flow CO2 hydras... |
Bioorg Med Chem Lett 24: 1776-9 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.030 BindingDB Entry DOI: 10.7270/Q25D8TC6 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM50008349
(CHEMBL3235175)Show SMILES NS(=O)(=O)c1ccc(cc1)-n1cc([nH]c1=S)-c1ccccc1 Show InChI InChI=1S/C15H13N3O2S2/c16-22(19,20)13-8-6-12(7-9-13)18-10-14(17-15(18)21)11-4-2-1-3-5-11/h1-10H,(H,17,21)(H2,16,19,20) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 21 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Cagliari
Curated by ChEMBL
| Assay Description Inhibition of human recombinant transmembrane tumor associated carbonic anhydrase-12 incubated for 15 mins prior to testing by stopped-flow CO2 hydra... |
Bioorg Med Chem Lett 24: 1776-9 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.030 BindingDB Entry DOI: 10.7270/Q25D8TC6 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM50008323
(CHEMBL3235166)Show SMILES NS(=O)(=O)c1ccc(cc1)N(Cc1ccc(Cl)cc1)\C=C\C(=O)C(F)(F)F Show InChI InChI=1S/C17H14ClF3N2O3S/c18-13-3-1-12(2-4-13)11-23(10-9-16(24)17(19,20)21)14-5-7-15(8-6-14)27(22,25)26/h1-10H,11H2,(H2,22,25,26)/b10-9+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 24 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Cagliari
Curated by ChEMBL
| Assay Description Inhibition of human recombinant transmembrane tumor associated carbonic anhydrase-12 incubated for 15 mins prior to testing by stopped-flow CO2 hydra... |
Bioorg Med Chem Lett 24: 1776-9 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.030 BindingDB Entry DOI: 10.7270/Q25D8TC6 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM50008340
(CHEMBL3235171)Show SMILES CCOC(=O)NC(=S)N(CC(=O)c1ccccc1)c1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C18H19N3O5S2/c1-2-26-18(23)20-17(27)21(12-16(22)13-6-4-3-5-7-13)14-8-10-15(11-9-14)28(19,24)25/h3-11H,2,12H2,1H3,(H2,19,24,25)(H,20,23,27) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 24 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Cagliari
Curated by ChEMBL
| Assay Description Inhibition of human recombinant transmembrane tumor associated carbonic anhydrase-12 incubated for 15 mins prior to testing by stopped-flow CO2 hydra... |
Bioorg Med Chem Lett 24: 1776-9 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.030 BindingDB Entry DOI: 10.7270/Q25D8TC6 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM10880
(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| 25 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Cagliari
Curated by ChEMBL
| Assay Description Inhibition of human recombinant transmembrane tumor associated carbonic anhydrase-9 incubated for 15 mins prior to testing by stopped-flow CO2 hydras... |
Bioorg Med Chem Lett 24: 1776-9 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.030 BindingDB Entry DOI: 10.7270/Q25D8TC6 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50008340
(CHEMBL3235171)Show SMILES CCOC(=O)NC(=S)N(CC(=O)c1ccccc1)c1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C18H19N3O5S2/c1-2-26-18(23)20-17(27)21(12-16(22)13-6-4-3-5-7-13)14-8-10-15(11-9-14)28(19,24)25/h3-11H,2,12H2,1H3,(H2,19,24,25)(H,20,23,27) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 25 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Cagliari
Curated by ChEMBL
| Assay Description Inhibition of human recombinant transmembrane tumor associated carbonic anhydrase-9 incubated for 15 mins prior to testing by stopped-flow CO2 hydras... |
Bioorg Med Chem Lett 24: 1776-9 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.030 BindingDB Entry DOI: 10.7270/Q25D8TC6 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50008346
(CHEMBL3235174)Show SMILES NS(=O)(=O)c1ccc(cc1)-n1cc([nH]c1=O)-c1ccc(F)cc1 Show InChI InChI=1S/C15H12FN3O3S/c16-11-3-1-10(2-4-11)14-9-19(15(20)18-14)12-5-7-13(8-6-12)23(17,21)22/h1-9H,(H,18,20)(H2,17,21,22) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 25 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Cagliari
Curated by ChEMBL
| Assay Description Inhibition of human recombinant transmembrane tumor associated carbonic anhydrase-9 incubated for 15 mins prior to testing by stopped-flow CO2 hydras... |
Bioorg Med Chem Lett 24: 1776-9 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.030 BindingDB Entry DOI: 10.7270/Q25D8TC6 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50008343
(CHEMBL3235172)Show SMILES CCOC(=O)NC(=S)N(CC(=O)c1ccc(Cl)cc1)c1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C18H18ClN3O5S2/c1-2-27-18(24)21-17(28)22(11-16(23)12-3-5-13(19)6-4-12)14-7-9-15(10-8-14)29(20,25)26/h3-10H,2,11H2,1H3,(H2,20,25,26)(H,21,24,28) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 25 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Cagliari
Curated by ChEMBL
| Assay Description Inhibition of human recombinant transmembrane tumor associated carbonic anhydrase-9 incubated for 15 mins prior to testing by stopped-flow CO2 hydras... |
Bioorg Med Chem Lett 24: 1776-9 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.030 BindingDB Entry DOI: 10.7270/Q25D8TC6 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM50008332
(CHEMBL3235168)Show SMILES NS(=O)(=O)c1ccc(cc1)N(CC(=O)c1ccc(Cl)cc1)\C=C\C(=O)C(F)(F)F Show InChI InChI=1S/C18H14ClF3N2O4S/c19-13-3-1-12(2-4-13)16(25)11-24(10-9-17(26)18(20,21)22)14-5-7-15(8-6-14)29(23,27)28/h1-10H,11H2,(H2,23,27,28)/b10-9+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 27 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Cagliari
Curated by ChEMBL
| Assay Description Inhibition of human recombinant transmembrane tumor associated carbonic anhydrase-12 incubated for 15 mins prior to testing by stopped-flow CO2 hydra... |
Bioorg Med Chem Lett 24: 1776-9 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.030 BindingDB Entry DOI: 10.7270/Q25D8TC6 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM50008338
(CHEMBL3235170)Show SMILES Cc1ccc(cc1)C(=O)CN(\C=C\C(=O)C(F)(F)F)c1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C19H17F3N2O4S/c1-13-2-4-14(5-3-13)17(25)12-24(11-10-18(26)19(20,21)22)15-6-8-16(9-7-15)29(23,27)28/h2-11H,12H2,1H3,(H2,23,27,28)/b11-10+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 28 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Cagliari
Curated by ChEMBL
| Assay Description Inhibition of human recombinant transmembrane tumor associated carbonic anhydrase-12 incubated for 15 mins prior to testing by stopped-flow CO2 hydra... |
Bioorg Med Chem Lett 24: 1776-9 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.030 BindingDB Entry DOI: 10.7270/Q25D8TC6 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM50008327
(CHEMBL3235167)Show SMILES NS(=O)(=O)c1ccc(cc1)N(CC(=O)c1ccccc1)\C=C\C(=O)C(F)(F)F Show InChI InChI=1S/C18H15F3N2O4S/c19-18(20,21)17(25)10-11-23(12-16(24)13-4-2-1-3-5-13)14-6-8-15(9-7-14)28(22,26)27/h1-11H,12H2,(H2,22,26,27)/b11-10+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 29 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Cagliari
Curated by ChEMBL
| Assay Description Inhibition of human recombinant transmembrane tumor associated carbonic anhydrase-12 incubated for 15 mins prior to testing by stopped-flow CO2 hydra... |
Bioorg Med Chem Lett 24: 1776-9 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.030 BindingDB Entry DOI: 10.7270/Q25D8TC6 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM50008334
(CHEMBL3235169)Show SMILES NS(=O)(=O)c1ccc(cc1)N(CC(=O)c1ccc(F)cc1)\C=C\C(=O)C(F)(F)F Show InChI InChI=1S/C18H14F4N2O4S/c19-13-3-1-12(2-4-13)16(25)11-24(10-9-17(26)18(20,21)22)14-5-7-15(8-6-14)29(23,27)28/h1-10H,11H2,(H2,23,27,28)/b10-9+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 29 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Cagliari
Curated by ChEMBL
| Assay Description Inhibition of human recombinant transmembrane tumor associated carbonic anhydrase-12 incubated for 15 mins prior to testing by stopped-flow CO2 hydra... |
Bioorg Med Chem Lett 24: 1776-9 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.030 BindingDB Entry DOI: 10.7270/Q25D8TC6 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50008354
(CHEMBL3235177)Show SMILES COc1ccc(cc1)-c1cn(-c2ccc(cc2)S(N)(=O)=O)c(=S)[nH]1 Show InChI InChI=1S/C16H15N3O3S2/c1-22-13-6-2-11(3-7-13)15-10-19(16(23)18-15)12-4-8-14(9-5-12)24(17,20)21/h2-10H,1H3,(H,18,23)(H2,17,20,21) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Cagliari
Curated by ChEMBL
| Assay Description Inhibition of human recombinant transmembrane tumor associated carbonic anhydrase-9 incubated for 15 mins prior to testing by stopped-flow CO2 hydras... |
Bioorg Med Chem Lett 24: 1776-9 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.030 BindingDB Entry DOI: 10.7270/Q25D8TC6 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50008323
(CHEMBL3235166)Show SMILES NS(=O)(=O)c1ccc(cc1)N(Cc1ccc(Cl)cc1)\C=C\C(=O)C(F)(F)F Show InChI InChI=1S/C17H14ClF3N2O3S/c18-13-3-1-12(2-4-13)11-23(10-9-16(24)17(19,20)21)14-5-7-15(8-6-14)27(22,25)26/h1-10H,11H2,(H2,22,25,26)/b10-9+ | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 33 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Cagliari
Curated by ChEMBL
| Assay Description Inhibition of human recombinant transmembrane tumor associated carbonic anhydrase-9 incubated for 15 mins prior to testing by stopped-flow CO2 hydras... |
Bioorg Med Chem Lett 24: 1776-9 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.030 BindingDB Entry DOI: 10.7270/Q25D8TC6 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50008345
(CHEMBL3235173)Show SMILES NS(=O)(=O)c1ccc(cc1)-n1cc([nH]c1=O)-c1ccccc1 Show InChI InChI=1S/C15H13N3O3S/c16-22(20,21)13-8-6-12(7-9-13)18-10-14(17-15(18)19)11-4-2-1-3-5-11/h1-10H,(H,17,19)(H2,16,20,21) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 34 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Cagliari
Curated by ChEMBL
| Assay Description Inhibition of human recombinant transmembrane tumor associated carbonic anhydrase-9 incubated for 15 mins prior to testing by stopped-flow CO2 hydras... |
Bioorg Med Chem Lett 24: 1776-9 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.030 BindingDB Entry DOI: 10.7270/Q25D8TC6 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM50008354
(CHEMBL3235177)Show SMILES COc1ccc(cc1)-c1cn(-c2ccc(cc2)S(N)(=O)=O)c(=S)[nH]1 Show InChI InChI=1S/C16H15N3O3S2/c1-22-13-6-2-11(3-7-13)15-10-19(16(23)18-15)12-4-8-14(9-5-12)24(17,20)21/h2-10H,1H3,(H,18,23)(H2,17,20,21) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 35 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Cagliari
Curated by ChEMBL
| Assay Description Inhibition of human recombinant transmembrane tumor associated carbonic anhydrase-12 incubated for 15 mins prior to testing by stopped-flow CO2 hydra... |
Bioorg Med Chem Lett 24: 1776-9 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.030 BindingDB Entry DOI: 10.7270/Q25D8TC6 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM50008322
(CHEMBL3235165)Show SMILES NS(=O)(=O)c1ccc(cc1)N(Cc1ccccc1)\C=C\C(=O)C(F)(F)F Show InChI InChI=1S/C17H15F3N2O3S/c18-17(19,20)16(23)10-11-22(12-13-4-2-1-3-5-13)14-6-8-15(9-7-14)26(21,24)25/h1-11H,12H2,(H2,21,24,25)/b11-10+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 36 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Cagliari
Curated by ChEMBL
| Assay Description Inhibition of human recombinant transmembrane tumor associated carbonic anhydrase-12 incubated for 15 mins prior to testing by stopped-flow CO2 hydra... |
Bioorg Med Chem Lett 24: 1776-9 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.030 BindingDB Entry DOI: 10.7270/Q25D8TC6 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM10857
(4-aminobenzene-1-sulfonamide | CHEMBL21 | Sulfanil...)Show InChI InChI=1S/C6H8N2O2S/c7-5-1-3-6(4-2-5)11(8,9)10/h1-4H,7H2,(H2,8,9,10) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| 37 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Cagliari
Curated by ChEMBL
| Assay Description Inhibition of human recombinant transmembrane tumor associated carbonic anhydrase-12 incubated for 15 mins prior to testing by stopped-flow CO2 hydra... |
Bioorg Med Chem Lett 24: 1776-9 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.030 BindingDB Entry DOI: 10.7270/Q25D8TC6 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50008350
(CHEMBL3235176)Show SMILES NS(=O)(=O)c1ccc(cc1)-n1cc([nH]c1=S)-c1ccc(F)cc1 Show InChI InChI=1S/C15H12FN3O2S2/c16-11-3-1-10(2-4-11)14-9-19(15(22)18-14)12-5-7-13(8-6-12)23(17,20)21/h1-9H,(H,18,22)(H2,17,20,21) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 37 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Cagliari
Curated by ChEMBL
| Assay Description Inhibition of human recombinant transmembrane tumor associated carbonic anhydrase-9 incubated for 15 mins prior to testing by stopped-flow CO2 hydras... |
Bioorg Med Chem Lett 24: 1776-9 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.030 BindingDB Entry DOI: 10.7270/Q25D8TC6 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM50008346
(CHEMBL3235174)Show SMILES NS(=O)(=O)c1ccc(cc1)-n1cc([nH]c1=O)-c1ccc(F)cc1 Show InChI InChI=1S/C15H12FN3O3S/c16-11-3-1-10(2-4-11)14-9-19(15(20)18-14)12-5-7-13(8-6-12)23(17,21)22/h1-9H,(H,18,20)(H2,17,21,22) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 38 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Cagliari
Curated by ChEMBL
| Assay Description Inhibition of human recombinant transmembrane tumor associated carbonic anhydrase-12 incubated for 15 mins prior to testing by stopped-flow CO2 hydra... |
Bioorg Med Chem Lett 24: 1776-9 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.030 BindingDB Entry DOI: 10.7270/Q25D8TC6 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50008322
(CHEMBL3235165)Show SMILES NS(=O)(=O)c1ccc(cc1)N(Cc1ccccc1)\C=C\C(=O)C(F)(F)F Show InChI InChI=1S/C17H15F3N2O3S/c18-17(19,20)16(23)10-11-22(12-13-4-2-1-3-5-13)14-6-8-15(9-7-14)26(21,24)25/h1-11H,12H2,(H2,21,24,25)/b11-10+ | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 39 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Cagliari
Curated by ChEMBL
| Assay Description Inhibition of human recombinant transmembrane tumor associated carbonic anhydrase-9 incubated for 15 mins prior to testing by stopped-flow CO2 hydras... |
Bioorg Med Chem Lett 24: 1776-9 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.030 BindingDB Entry DOI: 10.7270/Q25D8TC6 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM10880
(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| DrugBank PDB Article PubMed
| 250 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Cagliari
Curated by ChEMBL
| Assay Description Inhibition of human recombinant cytosolic human carbonic anhydrase-1 incubated for 15 mins prior to testing by stopped-flow CO2 hydrase assay |
Bioorg Med Chem Lett 24: 1776-9 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.030 BindingDB Entry DOI: 10.7270/Q25D8TC6 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50008354
(CHEMBL3235177)Show SMILES COc1ccc(cc1)-c1cn(-c2ccc(cc2)S(N)(=O)=O)c(=S)[nH]1 Show InChI InChI=1S/C16H15N3O3S2/c1-22-13-6-2-11(3-7-13)15-10-19(16(23)18-15)12-4-8-14(9-5-12)24(17,20)21/h2-10H,1H3,(H,18,23)(H2,17,20,21) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 274 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Cagliari
Curated by ChEMBL
| Assay Description Inhibition of human recombinant cytosolic human carbonic anhydrase-2 incubated for 15 mins prior to testing by stopped-flow CO2 hydrase assay |
Bioorg Med Chem Lett 24: 1776-9 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.030 BindingDB Entry DOI: 10.7270/Q25D8TC6 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50008332
(CHEMBL3235168)Show SMILES NS(=O)(=O)c1ccc(cc1)N(CC(=O)c1ccc(Cl)cc1)\C=C\C(=O)C(F)(F)F Show InChI InChI=1S/C18H14ClF3N2O4S/c19-13-3-1-12(2-4-13)16(25)11-24(10-9-17(26)18(20,21)22)14-5-7-15(8-6-14)29(23,27)28/h1-10H,11H2,(H2,23,27,28)/b10-9+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 275 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Cagliari
Curated by ChEMBL
| Assay Description Inhibition of human recombinant cytosolic human carbonic anhydrase-2 incubated for 15 mins prior to testing by stopped-flow CO2 hydrase assay |
Bioorg Med Chem Lett 24: 1776-9 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.030 BindingDB Entry DOI: 10.7270/Q25D8TC6 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50008322
(CHEMBL3235165)Show SMILES NS(=O)(=O)c1ccc(cc1)N(Cc1ccccc1)\C=C\C(=O)C(F)(F)F Show InChI InChI=1S/C17H15F3N2O3S/c18-17(19,20)16(23)10-11-22(12-13-4-2-1-3-5-13)14-6-8-15(9-7-14)26(21,24)25/h1-11H,12H2,(H2,21,24,25)/b11-10+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 276 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Cagliari
Curated by ChEMBL
| Assay Description Inhibition of human recombinant cytosolic human carbonic anhydrase-2 incubated for 15 mins prior to testing by stopped-flow CO2 hydrase assay |
Bioorg Med Chem Lett 24: 1776-9 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.030 BindingDB Entry DOI: 10.7270/Q25D8TC6 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM10857
(4-aminobenzene-1-sulfonamide | CHEMBL21 | Sulfanil...)Show InChI InChI=1S/C6H8N2O2S/c7-5-1-3-6(4-2-5)11(8,9)10/h1-4H,7H2,(H2,8,9,10) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| 294 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Cagliari
Curated by ChEMBL
| Assay Description Inhibition of human recombinant transmembrane tumor associated carbonic anhydrase-9 incubated for 15 mins prior to testing by stopped-flow CO2 hydras... |
Bioorg Med Chem Lett 24: 1776-9 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.030 BindingDB Entry DOI: 10.7270/Q25D8TC6 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50008349
(CHEMBL3235175)Show SMILES NS(=O)(=O)c1ccc(cc1)-n1cc([nH]c1=S)-c1ccccc1 Show InChI InChI=1S/C15H13N3O2S2/c16-22(19,20)13-8-6-12(7-9-13)18-10-14(17-15(18)21)11-4-2-1-3-5-11/h1-10H,(H,17,21)(H2,16,19,20) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 296 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Cagliari
Curated by ChEMBL
| Assay Description Inhibition of human recombinant cytosolic human carbonic anhydrase-2 incubated for 15 mins prior to testing by stopped-flow CO2 hydrase assay |
Bioorg Med Chem Lett 24: 1776-9 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.030 BindingDB Entry DOI: 10.7270/Q25D8TC6 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50008323
(CHEMBL3235166)Show SMILES NS(=O)(=O)c1ccc(cc1)N(Cc1ccc(Cl)cc1)\C=C\C(=O)C(F)(F)F Show InChI InChI=1S/C17H14ClF3N2O3S/c18-13-3-1-12(2-4-13)11-23(10-9-16(24)17(19,20)21)14-5-7-15(8-6-14)27(22,25)26/h1-10H,11H2,(H2,22,25,26)/b10-9+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 297 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Cagliari
Curated by ChEMBL
| Assay Description Inhibition of human recombinant cytosolic human carbonic anhydrase-2 incubated for 15 mins prior to testing by stopped-flow CO2 hydrase assay |
Bioorg Med Chem Lett 24: 1776-9 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.030 BindingDB Entry DOI: 10.7270/Q25D8TC6 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM10857
(4-aminobenzene-1-sulfonamide | CHEMBL21 | Sulfanil...)Show InChI InChI=1S/C6H8N2O2S/c7-5-1-3-6(4-2-5)11(8,9)10/h1-4H,7H2,(H2,8,9,10) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| 300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Cagliari
Curated by ChEMBL
| Assay Description Inhibition of human recombinant cytosolic human carbonic anhydrase-2 incubated for 15 mins prior to testing by stopped-flow CO2 hydrase assay |
Bioorg Med Chem Lett 24: 1776-9 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.030 BindingDB Entry DOI: 10.7270/Q25D8TC6 |
More data for this Ligand-Target Pair | 3D Structure (docked) |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50008322
(CHEMBL3235165)Show SMILES NS(=O)(=O)c1ccc(cc1)N(Cc1ccccc1)\C=C\C(=O)C(F)(F)F Show InChI InChI=1S/C17H15F3N2O3S/c18-17(19,20)16(23)10-11-22(12-13-4-2-1-3-5-13)14-6-8-15(9-7-14)26(21,24)25/h1-11H,12H2,(H2,21,24,25)/b11-10+ | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 302 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Cagliari
Curated by ChEMBL
| Assay Description Inhibition of human recombinant cytosolic human carbonic anhydrase-1 incubated for 15 mins prior to testing by stopped-flow CO2 hydrase assay |
Bioorg Med Chem Lett 24: 1776-9 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.030 BindingDB Entry DOI: 10.7270/Q25D8TC6 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50008346
(CHEMBL3235174)Show SMILES NS(=O)(=O)c1ccc(cc1)-n1cc([nH]c1=O)-c1ccc(F)cc1 Show InChI InChI=1S/C15H12FN3O3S/c16-11-3-1-10(2-4-11)14-9-19(15(20)18-14)12-5-7-13(8-6-12)23(17,21)22/h1-9H,(H,18,20)(H2,17,21,22) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 336 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Cagliari
Curated by ChEMBL
| Assay Description Inhibition of human recombinant cytosolic human carbonic anhydrase-2 incubated for 15 mins prior to testing by stopped-flow CO2 hydrase assay |
Bioorg Med Chem Lett 24: 1776-9 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.030 BindingDB Entry DOI: 10.7270/Q25D8TC6 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50008332
(CHEMBL3235168)Show SMILES NS(=O)(=O)c1ccc(cc1)N(CC(=O)c1ccc(Cl)cc1)\C=C\C(=O)C(F)(F)F Show InChI InChI=1S/C18H14ClF3N2O4S/c19-13-3-1-12(2-4-13)16(25)11-24(10-9-17(26)18(20,21)22)14-5-7-15(8-6-14)29(23,27)28/h1-10H,11H2,(H2,23,27,28)/b10-9+ | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 336 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Cagliari
Curated by ChEMBL
| Assay Description Inhibition of human recombinant cytosolic human carbonic anhydrase-1 incubated for 15 mins prior to testing by stopped-flow CO2 hydrase assay |
Bioorg Med Chem Lett 24: 1776-9 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.030 BindingDB Entry DOI: 10.7270/Q25D8TC6 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50008350
(CHEMBL3235176)Show SMILES NS(=O)(=O)c1ccc(cc1)-n1cc([nH]c1=S)-c1ccc(F)cc1 Show InChI InChI=1S/C15H12FN3O2S2/c16-11-3-1-10(2-4-11)14-9-19(15(22)18-14)12-5-7-13(8-6-12)23(17,20)21/h1-9H,(H,18,22)(H2,17,20,21) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 351 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Cagliari
Curated by ChEMBL
| Assay Description Inhibition of human recombinant cytosolic human carbonic anhydrase-2 incubated for 15 mins prior to testing by stopped-flow CO2 hydrase assay |
Bioorg Med Chem Lett 24: 1776-9 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.030 BindingDB Entry DOI: 10.7270/Q25D8TC6 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50008345
(CHEMBL3235173)Show SMILES NS(=O)(=O)c1ccc(cc1)-n1cc([nH]c1=O)-c1ccccc1 Show InChI InChI=1S/C15H13N3O3S/c16-22(20,21)13-8-6-12(7-9-13)18-10-14(17-15(18)19)11-4-2-1-3-5-11/h1-10H,(H,17,19)(H2,16,20,21) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 375 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Cagliari
Curated by ChEMBL
| Assay Description Inhibition of human recombinant cytosolic human carbonic anhydrase-2 incubated for 15 mins prior to testing by stopped-flow CO2 hydrase assay |
Bioorg Med Chem Lett 24: 1776-9 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.030 BindingDB Entry DOI: 10.7270/Q25D8TC6 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50008327
(CHEMBL3235167)Show SMILES NS(=O)(=O)c1ccc(cc1)N(CC(=O)c1ccccc1)\C=C\C(=O)C(F)(F)F Show InChI InChI=1S/C18H15F3N2O4S/c19-18(20,21)17(25)10-11-23(12-16(24)13-4-2-1-3-5-13)14-6-8-15(9-7-14)28(22,26)27/h1-11H,12H2,(H2,22,26,27)/b11-10+ | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 397 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Cagliari
Curated by ChEMBL
| Assay Description Inhibition of human recombinant cytosolic human carbonic anhydrase-1 incubated for 15 mins prior to testing by stopped-flow CO2 hydrase assay |
Bioorg Med Chem Lett 24: 1776-9 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.030 BindingDB Entry DOI: 10.7270/Q25D8TC6 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50008323
(CHEMBL3235166)Show SMILES NS(=O)(=O)c1ccc(cc1)N(Cc1ccc(Cl)cc1)\C=C\C(=O)C(F)(F)F Show InChI InChI=1S/C17H14ClF3N2O3S/c18-13-3-1-12(2-4-13)11-23(10-9-16(24)17(19,20)21)14-5-7-15(8-6-14)27(22,25)26/h1-10H,11H2,(H2,22,25,26)/b10-9+ | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 405 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Cagliari
Curated by ChEMBL
| Assay Description Inhibition of human recombinant cytosolic human carbonic anhydrase-1 incubated for 15 mins prior to testing by stopped-flow CO2 hydrase assay |
Bioorg Med Chem Lett 24: 1776-9 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.030 BindingDB Entry DOI: 10.7270/Q25D8TC6 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50008338
(CHEMBL3235170)Show SMILES Cc1ccc(cc1)C(=O)CN(\C=C\C(=O)C(F)(F)F)c1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C19H17F3N2O4S/c1-13-2-4-14(5-3-13)17(25)12-24(11-10-18(26)19(20,21)22)15-6-8-16(9-7-15)29(23,27)28/h2-11H,12H2,1H3,(H2,23,27,28)/b11-10+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 408 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Cagliari
Curated by ChEMBL
| Assay Description Inhibition of human recombinant cytosolic human carbonic anhydrase-2 incubated for 15 mins prior to testing by stopped-flow CO2 hydrase assay |
Bioorg Med Chem Lett 24: 1776-9 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.030 BindingDB Entry DOI: 10.7270/Q25D8TC6 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50008354
(CHEMBL3235177)Show SMILES COc1ccc(cc1)-c1cn(-c2ccc(cc2)S(N)(=O)=O)c(=S)[nH]1 Show InChI InChI=1S/C16H15N3O3S2/c1-22-13-6-2-11(3-7-13)15-10-19(16(23)18-15)12-4-8-14(9-5-12)24(17,20)21/h2-10H,1H3,(H,18,23)(H2,17,20,21) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 411 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Cagliari
Curated by ChEMBL
| Assay Description Inhibition of human recombinant cytosolic human carbonic anhydrase-1 incubated for 15 mins prior to testing by stopped-flow CO2 hydrase assay |
Bioorg Med Chem Lett 24: 1776-9 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.030 BindingDB Entry DOI: 10.7270/Q25D8TC6 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50008340
(CHEMBL3235171)Show SMILES CCOC(=O)NC(=S)N(CC(=O)c1ccccc1)c1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C18H19N3O5S2/c1-2-26-18(23)20-17(27)21(12-16(22)13-6-4-3-5-7-13)14-8-10-15(11-9-14)28(19,24)25/h3-11H,2,12H2,1H3,(H2,19,24,25)(H,20,23,27) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 415 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Cagliari
Curated by ChEMBL
| Assay Description Inhibition of human recombinant cytosolic human carbonic anhydrase-2 incubated for 15 mins prior to testing by stopped-flow CO2 hydrase assay |
Bioorg Med Chem Lett 24: 1776-9 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.030 BindingDB Entry DOI: 10.7270/Q25D8TC6 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50008334
(CHEMBL3235169)Show SMILES NS(=O)(=O)c1ccc(cc1)N(CC(=O)c1ccc(F)cc1)\C=C\C(=O)C(F)(F)F Show InChI InChI=1S/C18H14F4N2O4S/c19-13-3-1-12(2-4-13)16(25)11-24(10-9-17(26)18(20,21)22)14-5-7-15(8-6-14)29(23,27)28/h1-10H,11H2,(H2,23,27,28)/b10-9+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 419 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Cagliari
Curated by ChEMBL
| Assay Description Inhibition of human recombinant cytosolic human carbonic anhydrase-2 incubated for 15 mins prior to testing by stopped-flow CO2 hydrase assay |
Bioorg Med Chem Lett 24: 1776-9 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.030 BindingDB Entry DOI: 10.7270/Q25D8TC6 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50008327
(CHEMBL3235167)Show SMILES NS(=O)(=O)c1ccc(cc1)N(CC(=O)c1ccccc1)\C=C\C(=O)C(F)(F)F Show InChI InChI=1S/C18H15F3N2O4S/c19-18(20,21)17(25)10-11-23(12-16(24)13-4-2-1-3-5-13)14-6-8-15(9-7-14)28(22,26)27/h1-11H,12H2,(H2,22,26,27)/b11-10+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 421 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Cagliari
Curated by ChEMBL
| Assay Description Inhibition of human recombinant cytosolic human carbonic anhydrase-2 incubated for 15 mins prior to testing by stopped-flow CO2 hydrase assay |
Bioorg Med Chem Lett 24: 1776-9 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.030 BindingDB Entry DOI: 10.7270/Q25D8TC6 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50008334
(CHEMBL3235169)Show SMILES NS(=O)(=O)c1ccc(cc1)N(CC(=O)c1ccc(F)cc1)\C=C\C(=O)C(F)(F)F Show InChI InChI=1S/C18H14F4N2O4S/c19-13-3-1-12(2-4-13)16(25)11-24(10-9-17(26)18(20,21)22)14-5-7-15(8-6-14)29(23,27)28/h1-10H,11H2,(H2,23,27,28)/b10-9+ | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 433 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Cagliari
Curated by ChEMBL
| Assay Description Inhibition of human recombinant cytosolic human carbonic anhydrase-1 incubated for 15 mins prior to testing by stopped-flow CO2 hydrase assay |
Bioorg Med Chem Lett 24: 1776-9 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.030 BindingDB Entry DOI: 10.7270/Q25D8TC6 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50008338
(CHEMBL3235170)Show SMILES Cc1ccc(cc1)C(=O)CN(\C=C\C(=O)C(F)(F)F)c1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C19H17F3N2O4S/c1-13-2-4-14(5-3-13)17(25)12-24(11-10-18(26)19(20,21)22)15-6-8-16(9-7-15)29(23,27)28/h2-11H,12H2,1H3,(H2,23,27,28)/b11-10+ | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 455 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Cagliari
Curated by ChEMBL
| Assay Description Inhibition of human recombinant cytosolic human carbonic anhydrase-1 incubated for 15 mins prior to testing by stopped-flow CO2 hydrase assay |
Bioorg Med Chem Lett 24: 1776-9 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.030 BindingDB Entry DOI: 10.7270/Q25D8TC6 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50008346
(CHEMBL3235174)Show SMILES NS(=O)(=O)c1ccc(cc1)-n1cc([nH]c1=O)-c1ccc(F)cc1 Show InChI InChI=1S/C15H12FN3O3S/c16-11-3-1-10(2-4-11)14-9-19(15(20)18-14)12-5-7-13(8-6-12)23(17,21)22/h1-9H,(H,18,20)(H2,17,21,22) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 497 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Cagliari
Curated by ChEMBL
| Assay Description Inhibition of human recombinant cytosolic human carbonic anhydrase-1 incubated for 15 mins prior to testing by stopped-flow CO2 hydrase assay |
Bioorg Med Chem Lett 24: 1776-9 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.030 BindingDB Entry DOI: 10.7270/Q25D8TC6 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50008350
(CHEMBL3235176)Show SMILES NS(=O)(=O)c1ccc(cc1)-n1cc([nH]c1=S)-c1ccc(F)cc1 Show InChI InChI=1S/C15H12FN3O2S2/c16-11-3-1-10(2-4-11)14-9-19(15(22)18-14)12-5-7-13(8-6-12)23(17,20)21/h1-9H,(H,18,22)(H2,17,20,21) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 498 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Cagliari
Curated by ChEMBL
| Assay Description Inhibition of human recombinant cytosolic human carbonic anhydrase-1 incubated for 15 mins prior to testing by stopped-flow CO2 hydrase assay |
Bioorg Med Chem Lett 24: 1776-9 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.030 BindingDB Entry DOI: 10.7270/Q25D8TC6 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50008340
(CHEMBL3235171)Show SMILES CCOC(=O)NC(=S)N(CC(=O)c1ccccc1)c1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C18H19N3O5S2/c1-2-26-18(23)20-17(27)21(12-16(22)13-6-4-3-5-7-13)14-8-10-15(11-9-14)28(19,24)25/h3-11H,2,12H2,1H3,(H2,19,24,25)(H,20,23,27) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 498 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Cagliari
Curated by ChEMBL
| Assay Description Inhibition of human recombinant cytosolic human carbonic anhydrase-1 incubated for 15 mins prior to testing by stopped-flow CO2 hydrase assay |
Bioorg Med Chem Lett 24: 1776-9 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.030 BindingDB Entry DOI: 10.7270/Q25D8TC6 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50008343
(CHEMBL3235172)Show SMILES CCOC(=O)NC(=S)N(CC(=O)c1ccc(Cl)cc1)c1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C18H18ClN3O5S2/c1-2-27-18(24)21-17(28)22(11-16(23)12-3-5-13(19)6-4-12)14-7-9-15(10-8-14)29(20,25)26/h3-10H,2,11H2,1H3,(H2,20,25,26)(H,21,24,28) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 510 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Cagliari
Curated by ChEMBL
| Assay Description Inhibition of human recombinant cytosolic human carbonic anhydrase-2 incubated for 15 mins prior to testing by stopped-flow CO2 hydrase assay |
Bioorg Med Chem Lett 24: 1776-9 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.030 BindingDB Entry DOI: 10.7270/Q25D8TC6 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50008349
(CHEMBL3235175)Show SMILES NS(=O)(=O)c1ccc(cc1)-n1cc([nH]c1=S)-c1ccccc1 Show InChI InChI=1S/C15H13N3O2S2/c16-22(19,20)13-8-6-12(7-9-13)18-10-14(17-15(18)21)11-4-2-1-3-5-11/h1-10H,(H,17,21)(H2,16,19,20) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 521 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Cagliari
Curated by ChEMBL
| Assay Description Inhibition of human recombinant cytosolic human carbonic anhydrase-1 incubated for 15 mins prior to testing by stopped-flow CO2 hydrase assay |
Bioorg Med Chem Lett 24: 1776-9 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.030 BindingDB Entry DOI: 10.7270/Q25D8TC6 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50008345
(CHEMBL3235173)Show SMILES NS(=O)(=O)c1ccc(cc1)-n1cc([nH]c1=O)-c1ccccc1 Show InChI InChI=1S/C15H13N3O3S/c16-22(20,21)13-8-6-12(7-9-13)18-10-14(17-15(18)19)11-4-2-1-3-5-11/h1-10H,(H,17,19)(H2,16,20,21) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 572 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Cagliari
Curated by ChEMBL
| Assay Description Inhibition of human recombinant cytosolic human carbonic anhydrase-1 incubated for 15 mins prior to testing by stopped-flow CO2 hydrase assay |
Bioorg Med Chem Lett 24: 1776-9 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.030 BindingDB Entry DOI: 10.7270/Q25D8TC6 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50008343
(CHEMBL3235172)Show SMILES CCOC(=O)NC(=S)N(CC(=O)c1ccc(Cl)cc1)c1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C18H18ClN3O5S2/c1-2-27-18(24)21-17(28)22(11-16(23)12-3-5-13(19)6-4-12)14-7-9-15(10-8-14)29(20,25)26/h3-10H,2,11H2,1H3,(H2,20,25,26)(H,21,24,28) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 593 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Cagliari
Curated by ChEMBL
| Assay Description Inhibition of human recombinant cytosolic human carbonic anhydrase-1 incubated for 15 mins prior to testing by stopped-flow CO2 hydrase assay |
Bioorg Med Chem Lett 24: 1776-9 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.030 BindingDB Entry DOI: 10.7270/Q25D8TC6 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM10857
(4-aminobenzene-1-sulfonamide | CHEMBL21 | Sulfanil...)Show InChI InChI=1S/C6H8N2O2S/c7-5-1-3-6(4-2-5)11(8,9)10/h1-4H,7H2,(H2,8,9,10) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| 2.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Cagliari
Curated by ChEMBL
| Assay Description Inhibition of human recombinant cytosolic human carbonic anhydrase-1 incubated for 15 mins prior to testing by stopped-flow CO2 hydrase assay |
Bioorg Med Chem Lett 24: 1776-9 (2014)
Article DOI: 10.1016/j.bmcl.2014.02.030 BindingDB Entry DOI: 10.7270/Q25D8TC6 |
More data for this Ligand-Target Pair | |