Found 58 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50023344
(CHEMBL3334569)Show SMILES C[C@@H](c1ccn2nccc2c1)n1nnc2ncc(nc12)-c1cnn(CCO)c1 |r| Show InChI InChI=1S/C18H17N9O/c1-12(13-3-5-26-15(8-13)2-4-20-26)27-18-17(23-24-27)19-10-16(22-18)14-9-21-25(11-14)6-7-28/h2-5,8-12,28H,6-7H2,1H3/t12-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Hutchison MediPharma Limited
Curated by ChEMBL
| Assay Description
Inhibition of c-Met autophosphorylation in human NCI-H441 cells for 1 hr by ELISA |
J Med Chem 57: 7577-89 (2014)
Article DOI: 10.1021/jm500510f
BindingDB Entry DOI: 10.7270/Q2JD4ZCR |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50023342
(CHEMBL3334567)Show SMILES C[C@@H](c1ccc2nccn2c1)n1nnc2ncc(nc12)-c1cnn(C)c1 |r| Show InChI InChI=1S/C17H15N9/c1-11(12-3-4-15-18-5-6-25(15)10-12)26-17-16(22-23-26)19-8-14(21-17)13-7-20-24(2)9-13/h3-11H,1-2H3/t11-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
PDB
UniChem
Similars
| PDB
Article
PubMed
| n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Hutchison MediPharma Limited
Curated by ChEMBL
| Assay Description
Inhibition of c-Met autophosphorylation in human NCI-H441 cells for 1 hr by ELISA |
J Med Chem 57: 7577-89 (2014)
Article DOI: 10.1021/jm500510f
BindingDB Entry DOI: 10.7270/Q2JD4ZCR |
More data for this
Ligand-Target Pair | 
3D Structure (crystal) |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50023335
(CHEMBL3334540)Show SMILES FC(F)(F)Cn1cc(cn1)-c1cnc2nnn(Cc3ccc4nccn4c3)c2n1 Show InChI InChI=1S/C17H12F3N9/c18-17(19,20)10-28-9-12(5-23-28)13-6-22-15-16(24-13)29(26-25-15)8-11-1-2-14-21-3-4-27(14)7-11/h1-7,9H,8,10H2 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Hutchison MediPharma Limited
Curated by ChEMBL
| Assay Description
Inhibition of c-Met (unknown origin) using Poly E4Y substrate and ATP incubated for 45 mins by fluorescence polarization assay |
J Med Chem 57: 7577-89 (2014)
Article DOI: 10.1021/jm500510f
BindingDB Entry DOI: 10.7270/Q2JD4ZCR |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50023283
(CHEMBL3334556)Show SMILES OCCn1cc(cn1)-c1cnc2nnn(Cc3c[nH]c4ncccc34)c2n1 Show InChI InChI=1S/C17H15N9O/c27-5-4-25-9-12(7-21-25)14-8-20-16-17(22-14)26(24-23-16)10-11-6-19-15-13(11)2-1-3-18-15/h1-3,6-9,27H,4-5,10H2,(H,18,19) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Hutchison MediPharma Limited
Curated by ChEMBL
| Assay Description
Inhibition of c-Met (unknown origin) using Poly E4Y substrate and ATP incubated for 45 mins by fluorescence polarization assay |
J Med Chem 57: 7577-89 (2014)
Article DOI: 10.1021/jm500510f
BindingDB Entry DOI: 10.7270/Q2JD4ZCR |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50023333
(CHEMBL3334551)Show InChI InChI=1S/C17H15N9O/c27-6-5-24-11-13(8-20-24)15-9-18-16-17(21-15)26(23-22-16)10-12-2-4-25-14(7-12)1-3-19-25/h1-4,7-9,11,27H,5-6,10H2 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Hutchison MediPharma Limited
Curated by ChEMBL
| Assay Description
Inhibition of c-Met (unknown origin) using Poly E4Y substrate and ATP incubated for 45 mins by fluorescence polarization assay |
J Med Chem 57: 7577-89 (2014)
Article DOI: 10.1021/jm500510f
BindingDB Entry DOI: 10.7270/Q2JD4ZCR |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50023342
(CHEMBL3334567)Show SMILES C[C@@H](c1ccc2nccn2c1)n1nnc2ncc(nc12)-c1cnn(C)c1 |r| Show InChI InChI=1S/C17H15N9/c1-11(12-3-4-15-18-5-6-25(15)10-12)26-17-16(22-23-26)19-8-14(21-17)13-7-20-24(2)9-13/h3-11H,1-2H3/t11-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
PDB
UniChem
Similars
| PDB
Article
PubMed
| n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Hutchison MediPharma Limited
Curated by ChEMBL
| Assay Description
Inhibition of c-Met (unknown origin) using Poly E4Y substrate and ATP incubated for 45 mins by fluorescence polarization assay |
J Med Chem 57: 7577-89 (2014)
Article DOI: 10.1021/jm500510f
BindingDB Entry DOI: 10.7270/Q2JD4ZCR |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50396943
(CHEMBL2170816)Show InChI InChI=1S/C18H14N8/c1-25-11-14(8-21-25)16-9-20-17-18(22-16)26(24-23-17)10-12-4-5-15-13(7-12)3-2-6-19-15/h2-9,11H,10H2,1H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Hutchison MediPharma Limited
Curated by ChEMBL
| Assay Description
Inhibition of c-Met (unknown origin) using Poly E4Y substrate and ATP incubated for 45 mins by fluorescence polarization assay |
J Med Chem 57: 7577-89 (2014)
Article DOI: 10.1021/jm500510f
BindingDB Entry DOI: 10.7270/Q2JD4ZCR |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50023284
(CHEMBL3334557)Show SMILES Cn1cc(cn1)-c1cnc2nnn(Cc3n[nH]c4ncccc34)c2n1 Show InChI InChI=1S/C15H12N10/c1-24-7-9(5-18-24)11-6-17-14-15(19-11)25(23-22-14)8-12-10-3-2-4-16-13(10)21-20-12/h2-7H,8H2,1H3,(H,16,20,21) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Hutchison MediPharma Limited
Curated by ChEMBL
| Assay Description
Inhibition of c-Met autophosphorylation in human NCI-H441 cells for 1 hr by ELISA |
J Med Chem 57: 7577-89 (2014)
Article DOI: 10.1021/jm500510f
BindingDB Entry DOI: 10.7270/Q2JD4ZCR |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50023339
(CHEMBL3334564)Show SMILES Fc1ccc(cc1)-c1cnc2nnn(Cc3n[nH]c4ncccc34)c2n1 Show InChI InChI=1S/C17H11FN8/c18-11-5-3-10(4-6-11)13-8-20-16-17(21-13)26(25-24-16)9-14-12-2-1-7-19-15(12)23-22-14/h1-8H,9H2,(H,19,22,23) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Hutchison MediPharma Limited
Curated by ChEMBL
| Assay Description
Inhibition of c-Met (unknown origin) using Poly E4Y substrate and ATP incubated for 45 mins by fluorescence polarization assay |
J Med Chem 57: 7577-89 (2014)
Article DOI: 10.1021/jm500510f
BindingDB Entry DOI: 10.7270/Q2JD4ZCR |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50023289
(CHEMBL3334542)Show InChI InChI=1S/C16H13N9/c1-23-10-12(6-19-23)13-7-18-15-16(20-13)25(22-21-15)9-11-2-3-14-17-4-5-24(14)8-11/h2-8,10H,9H2,1H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Hutchison MediPharma Limited
Curated by ChEMBL
| Assay Description
Inhibition of c-Met (unknown origin) using Poly E4Y substrate and ATP incubated for 45 mins by fluorescence polarization assay |
J Med Chem 57: 7577-89 (2014)
Article DOI: 10.1021/jm500510f
BindingDB Entry DOI: 10.7270/Q2JD4ZCR |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50023306
(CHEMBL3334549)Show SMILES OCCn1cc(cn1)-c1cnc2nnn(Cc3n[nH]c4ncccc34)c2n1 Show InChI InChI=1S/C16H14N10O/c27-5-4-25-8-10(6-19-25)12-7-18-15-16(20-12)26(24-23-15)9-13-11-2-1-3-17-14(11)22-21-13/h1-3,6-8,27H,4-5,9H2,(H,17,21,22) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Hutchison MediPharma Limited
Curated by ChEMBL
| Assay Description
Inhibition of c-Met (unknown origin) using Poly E4Y substrate and ATP incubated for 45 mins by fluorescence polarization assay |
J Med Chem 57: 7577-89 (2014)
Article DOI: 10.1021/jm500510f
BindingDB Entry DOI: 10.7270/Q2JD4ZCR |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50396943
(CHEMBL2170816)Show InChI InChI=1S/C18H14N8/c1-25-11-14(8-21-25)16-9-20-17-18(22-16)26(24-23-17)10-12-4-5-15-13(7-12)3-2-6-19-15/h2-9,11H,10H2,1H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Hutchison MediPharma Limited
Curated by ChEMBL
| Assay Description
Inhibition of c-Met autophosphorylation in human NCI-H441 cells for 1 hr by ELISA |
J Med Chem 57: 7577-89 (2014)
Article DOI: 10.1021/jm500510f
BindingDB Entry DOI: 10.7270/Q2JD4ZCR |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50023288
(CHEMBL3334541)Show InChI InChI=1S/C14H11N9S/c1-22-6-8(3-17-22)11-4-15-13-14(18-11)23(21-20-13)7-9-2-10-12(24-9)5-16-19-10/h2-6H,7H2,1H3,(H,16,19) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Hutchison MediPharma Limited
Curated by ChEMBL
| Assay Description
Inhibition of c-Met (unknown origin) using Poly E4Y substrate and ATP incubated for 45 mins by fluorescence polarization assay |
J Med Chem 57: 7577-89 (2014)
Article DOI: 10.1021/jm500510f
BindingDB Entry DOI: 10.7270/Q2JD4ZCR |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50023332
(CHEMBL3334550)Show InChI InChI=1S/C17H15N9O/c27-6-5-25-11-13(7-20-25)14-8-19-16-17(21-14)26(23-22-16)10-12-1-2-15-18-3-4-24(15)9-12/h1-4,7-9,11,27H,5-6,10H2 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Hutchison MediPharma Limited
Curated by ChEMBL
| Assay Description
Inhibition of c-Met (unknown origin) using Poly E4Y substrate and ATP incubated for 45 mins by fluorescence polarization assay |
J Med Chem 57: 7577-89 (2014)
Article DOI: 10.1021/jm500510f
BindingDB Entry DOI: 10.7270/Q2JD4ZCR |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50023335
(CHEMBL3334540)Show SMILES FC(F)(F)Cn1cc(cn1)-c1cnc2nnn(Cc3ccc4nccn4c3)c2n1 Show InChI InChI=1S/C17H12F3N9/c18-17(19,20)10-28-9-12(5-23-28)13-6-22-15-16(24-13)29(26-25-15)8-11-1-2-14-21-3-4-27(14)7-11/h1-7,9H,8,10H2 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
Hutchison MediPharma Limited
Curated by ChEMBL
| Assay Description
Inhibition of c-Met autophosphorylation in human NCI-H441 cells for 1 hr by ELISA |
J Med Chem 57: 7577-89 (2014)
Article DOI: 10.1021/jm500510f
BindingDB Entry DOI: 10.7270/Q2JD4ZCR |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50023344
(CHEMBL3334569)Show SMILES C[C@@H](c1ccn2nccc2c1)n1nnc2ncc(nc12)-c1cnn(CCO)c1 |r| Show InChI InChI=1S/C18H17N9O/c1-12(13-3-5-26-15(8-13)2-4-20-26)27-18-17(23-24-27)19-10-16(22-18)14-9-21-25(11-14)6-7-28/h2-5,8-12,28H,6-7H2,1H3/t12-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
Hutchison MediPharma Limited
Curated by ChEMBL
| Assay Description
Inhibition of c-Met (unknown origin) using Poly E4Y substrate and ATP incubated for 45 mins by fluorescence polarization assay |
J Med Chem 57: 7577-89 (2014)
Article DOI: 10.1021/jm500510f
BindingDB Entry DOI: 10.7270/Q2JD4ZCR |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50023340
(CHEMBL3334565)Show InChI InChI=1S/C18H12FN7/c19-14-4-2-13(3-5-14)15-9-21-17-18(22-15)26(24-23-17)11-12-1-6-16-20-7-8-25(16)10-12/h1-10H,11H2 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
Hutchison MediPharma Limited
Curated by ChEMBL
| Assay Description
Inhibition of c-Met (unknown origin) using Poly E4Y substrate and ATP incubated for 45 mins by fluorescence polarization assay |
J Med Chem 57: 7577-89 (2014)
Article DOI: 10.1021/jm500510f
BindingDB Entry DOI: 10.7270/Q2JD4ZCR |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50023337
(CHEMBL3334562)Show SMILES N#Cc1ccc(cn1)-c1cnc2nnn(Cc3n[nH]c4ncccc34)c2n1 Show InChI InChI=1S/C17H10N10/c18-6-11-4-3-10(7-20-11)13-8-21-16-17(22-13)27(26-25-16)9-14-12-2-1-5-19-15(12)24-23-14/h1-5,7-8H,9H2,(H,19,23,24) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
Hutchison MediPharma Limited
Curated by ChEMBL
| Assay Description
Inhibition of c-Met (unknown origin) using Poly E4Y substrate and ATP incubated for 45 mins by fluorescence polarization assay |
J Med Chem 57: 7577-89 (2014)
Article DOI: 10.1021/jm500510f
BindingDB Entry DOI: 10.7270/Q2JD4ZCR |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50023333
(CHEMBL3334551)Show InChI InChI=1S/C17H15N9O/c27-6-5-24-11-13(8-20-24)15-9-18-16-17(21-15)26(23-22-16)10-12-2-4-25-14(7-12)1-3-19-25/h1-4,7-9,11,27H,5-6,10H2 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
Hutchison MediPharma Limited
Curated by ChEMBL
| Assay Description
Inhibition of c-Met autophosphorylation in human NCI-H441 cells for 1 hr by ELISA |
J Med Chem 57: 7577-89 (2014)
Article DOI: 10.1021/jm500510f
BindingDB Entry DOI: 10.7270/Q2JD4ZCR |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50023334
(CHEMBL3334552)Show SMILES FC(F)(F)Cn1cc(cn1)-c1cnc2nnn(Cc3n[nH]c4ncccc34)c2n1 Show InChI InChI=1S/C16H11F3N10/c17-16(18,19)8-28-6-9(4-22-28)11-5-21-14-15(23-11)29(27-26-14)7-12-10-2-1-3-20-13(10)25-24-12/h1-6H,7-8H2,(H,20,24,25) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Hutchison MediPharma Limited
Curated by ChEMBL
| Assay Description
Inhibition of c-Met autophosphorylation in human NCI-H441 cells for 1 hr by ELISA |
J Med Chem 57: 7577-89 (2014)
Article DOI: 10.1021/jm500510f
BindingDB Entry DOI: 10.7270/Q2JD4ZCR |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50023334
(CHEMBL3334552)Show SMILES FC(F)(F)Cn1cc(cn1)-c1cnc2nnn(Cc3n[nH]c4ncccc34)c2n1 Show InChI InChI=1S/C16H11F3N10/c17-16(18,19)8-28-6-9(4-22-28)11-5-21-14-15(23-11)29(27-26-14)7-12-10-2-1-3-20-13(10)25-24-12/h1-6H,7-8H2,(H,20,24,25) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
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| Article
PubMed
| n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
Hutchison MediPharma Limited
Curated by ChEMBL
| Assay Description
Inhibition of c-Met (unknown origin) using Poly E4Y substrate and ATP incubated for 45 mins by fluorescence polarization assay |
J Med Chem 57: 7577-89 (2014)
Article DOI: 10.1021/jm500510f
BindingDB Entry DOI: 10.7270/Q2JD4ZCR |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50023284
(CHEMBL3334557)Show SMILES Cn1cc(cn1)-c1cnc2nnn(Cc3n[nH]c4ncccc34)c2n1 Show InChI InChI=1S/C15H12N10/c1-24-7-9(5-18-24)11-6-17-14-15(19-11)25(23-22-14)8-12-10-3-2-4-16-13(10)21-20-12/h2-7H,8H2,1H3,(H,16,20,21) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
Hutchison MediPharma Limited
Curated by ChEMBL
| Assay Description
Inhibition of c-Met (unknown origin) using Poly E4Y substrate and ATP incubated for 45 mins by fluorescence polarization assay |
J Med Chem 57: 7577-89 (2014)
Article DOI: 10.1021/jm500510f
BindingDB Entry DOI: 10.7270/Q2JD4ZCR |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50023283
(CHEMBL3334556)Show SMILES OCCn1cc(cn1)-c1cnc2nnn(Cc3c[nH]c4ncccc34)c2n1 Show InChI InChI=1S/C17H15N9O/c27-5-4-25-9-12(7-21-25)14-8-20-16-17(22-14)26(24-23-16)10-11-6-19-15-13(11)2-1-3-18-15/h1-3,6-9,27H,4-5,10H2,(H,18,19) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Hutchison MediPharma Limited
Curated by ChEMBL
| Assay Description
Inhibition of c-Met autophosphorylation in human NCI-H441 cells for 1 hr by ELISA |
J Med Chem 57: 7577-89 (2014)
Article DOI: 10.1021/jm500510f
BindingDB Entry DOI: 10.7270/Q2JD4ZCR |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50023336
(CHEMBL3334561)Show SMILES FC(F)(F)Cn1cc(cn1)-c1cnc2nnn(Cc3ccn4nccc4c3)c2n1 Show InChI InChI=1S/C17H12F3N9/c18-17(19,20)10-27-9-12(6-23-27)14-7-21-15-16(24-14)29(26-25-15)8-11-2-4-28-13(5-11)1-3-22-28/h1-7,9H,8,10H2 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Hutchison MediPharma Limited
Curated by ChEMBL
| Assay Description
Inhibition of c-Met autophosphorylation in human NCI-H441 cells for 1 hr by ELISA |
J Med Chem 57: 7577-89 (2014)
Article DOI: 10.1021/jm500510f
BindingDB Entry DOI: 10.7270/Q2JD4ZCR |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50023287
(CHEMBL3334560)Show InChI InChI=1S/C16H12N8S/c1-23-8-11(6-19-23)13-7-18-15-16(20-13)24(22-21-15)9-12-4-10-5-17-3-2-14(10)25-12/h2-8H,9H2,1H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Hutchison MediPharma Limited
Curated by ChEMBL
| Assay Description
Inhibition of c-Met (unknown origin) using Poly E4Y substrate and ATP incubated for 45 mins by fluorescence polarization assay |
J Med Chem 57: 7577-89 (2014)
Article DOI: 10.1021/jm500510f
BindingDB Entry DOI: 10.7270/Q2JD4ZCR |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50023289
(CHEMBL3334542)Show InChI InChI=1S/C16H13N9/c1-23-10-12(6-19-23)13-7-18-15-16(20-13)25(22-21-15)9-11-2-3-14-17-4-5-24(14)8-11/h2-8,10H,9H2,1H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Hutchison MediPharma Limited
Curated by ChEMBL
| Assay Description
Inhibition of c-Met autophosphorylation in human NCI-H441 cells for 1 hr by ELISA |
J Med Chem 57: 7577-89 (2014)
Article DOI: 10.1021/jm500510f
BindingDB Entry DOI: 10.7270/Q2JD4ZCR |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50023340
(CHEMBL3334565)Show InChI InChI=1S/C18H12FN7/c19-14-4-2-13(3-5-14)15-9-21-17-18(22-15)26(24-23-17)11-12-1-6-16-20-7-8-25(16)10-12/h1-10H,11H2 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
Hutchison MediPharma Limited
Curated by ChEMBL
| Assay Description
Inhibition of c-Met autophosphorylation in human NCI-H441 cells for 1 hr by ELISA |
J Med Chem 57: 7577-89 (2014)
Article DOI: 10.1021/jm500510f
BindingDB Entry DOI: 10.7270/Q2JD4ZCR |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50023339
(CHEMBL3334564)Show SMILES Fc1ccc(cc1)-c1cnc2nnn(Cc3n[nH]c4ncccc34)c2n1 Show InChI InChI=1S/C17H11FN8/c18-11-5-3-10(4-6-11)13-8-20-16-17(21-13)26(25-24-16)9-14-12-2-1-7-19-15(12)23-22-14/h1-8H,9H2,(H,19,22,23) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
Hutchison MediPharma Limited
Curated by ChEMBL
| Assay Description
Inhibition of c-Met autophosphorylation in human NCI-H441 cells for 1 hr by ELISA |
J Med Chem 57: 7577-89 (2014)
Article DOI: 10.1021/jm500510f
BindingDB Entry DOI: 10.7270/Q2JD4ZCR |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50023336
(CHEMBL3334561)Show SMILES FC(F)(F)Cn1cc(cn1)-c1cnc2nnn(Cc3ccn4nccc4c3)c2n1 Show InChI InChI=1S/C17H12F3N9/c18-17(19,20)10-27-9-12(6-23-27)14-7-21-15-16(24-14)29(26-25-15)8-11-2-4-28-13(5-11)1-3-22-28/h1-7,9H,8,10H2 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Hutchison MediPharma Limited
Curated by ChEMBL
| Assay Description
Inhibition of c-Met (unknown origin) using Poly E4Y substrate and ATP incubated for 45 mins by fluorescence polarization assay |
J Med Chem 57: 7577-89 (2014)
Article DOI: 10.1021/jm500510f
BindingDB Entry DOI: 10.7270/Q2JD4ZCR |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50023338
(CHEMBL3334563)Show SMILES N#Cc1ccc(cn1)-c1cnc2nnn(Cc3ccc4nccn4c3)c2n1 Show InChI InChI=1S/C18H11N9/c19-7-14-3-2-13(8-21-14)15-9-22-17-18(23-15)27(25-24-17)11-12-1-4-16-20-5-6-26(16)10-12/h1-6,8-10H,11H2 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
Hutchison MediPharma Limited
Curated by ChEMBL
| Assay Description
Inhibition of c-Met (unknown origin) using Poly E4Y substrate and ATP incubated for 45 mins by fluorescence polarization assay |
J Med Chem 57: 7577-89 (2014)
Article DOI: 10.1021/jm500510f
BindingDB Entry DOI: 10.7270/Q2JD4ZCR |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50023293
(CHEMBL3334546)Show InChI InChI=1S/C16H13N9/c1-23-10-12(7-19-23)14-8-17-15-16(20-14)25(22-21-15)9-11-3-5-24-13(6-11)2-4-18-24/h2-8,10H,9H2,1H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
Hutchison MediPharma Limited
Curated by ChEMBL
| Assay Description
Inhibition of c-Met (unknown origin) using Poly E4Y substrate and ATP incubated for 45 mins by fluorescence polarization assay |
J Med Chem 57: 7577-89 (2014)
Article DOI: 10.1021/jm500510f
BindingDB Entry DOI: 10.7270/Q2JD4ZCR |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50023288
(CHEMBL3334541)Show InChI InChI=1S/C14H11N9S/c1-22-6-8(3-17-22)11-4-15-13-14(18-11)23(21-20-13)7-9-2-10-12(24-9)5-16-19-10/h2-6H,7H2,1H3,(H,16,19) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
Hutchison MediPharma Limited
Curated by ChEMBL
| Assay Description
Inhibition of c-Met autophosphorylation in human NCI-H441 cells for 1 hr by ELISA |
J Med Chem 57: 7577-89 (2014)
Article DOI: 10.1021/jm500510f
BindingDB Entry DOI: 10.7270/Q2JD4ZCR |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50023293
(CHEMBL3334546)Show InChI InChI=1S/C16H13N9/c1-23-10-12(7-19-23)14-8-17-15-16(20-14)25(22-21-15)9-11-3-5-24-13(6-11)2-4-18-24/h2-8,10H,9H2,1H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Hutchison MediPharma Limited
Curated by ChEMBL
| Assay Description
Inhibition of c-Met autophosphorylation in human NCI-H441 cells for 1 hr by ELISA |
J Med Chem 57: 7577-89 (2014)
Article DOI: 10.1021/jm500510f
BindingDB Entry DOI: 10.7270/Q2JD4ZCR |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50023292
(CHEMBL3334545)Show InChI InChI=1S/C15H12N10/c1-23-8-10(6-18-23)12-7-17-14-15(19-12)25(22-20-14)9-11-2-3-13-16-4-5-24(13)21-11/h2-8H,9H2,1H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
Hutchison MediPharma Limited
Curated by ChEMBL
| Assay Description
Inhibition of c-Met (unknown origin) using Poly E4Y substrate and ATP incubated for 45 mins by fluorescence polarization assay |
J Med Chem 57: 7577-89 (2014)
Article DOI: 10.1021/jm500510f
BindingDB Entry DOI: 10.7270/Q2JD4ZCR |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50023291
(CHEMBL3334544)Show InChI InChI=1S/C15H12N10/c1-23-8-11(4-18-23)12-5-16-14-15(20-12)25(22-21-14)7-10-2-3-13-17-9-19-24(13)6-10/h2-6,8-9H,7H2,1H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
Hutchison MediPharma Limited
Curated by ChEMBL
| Assay Description
Inhibition of c-Met (unknown origin) using Poly E4Y substrate and ATP incubated for 45 mins by fluorescence polarization assay |
J Med Chem 57: 7577-89 (2014)
Article DOI: 10.1021/jm500510f
BindingDB Entry DOI: 10.7270/Q2JD4ZCR |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50023338
(CHEMBL3334563)Show SMILES N#Cc1ccc(cn1)-c1cnc2nnn(Cc3ccc4nccn4c3)c2n1 Show InChI InChI=1S/C18H11N9/c19-7-14-3-2-13(8-21-14)15-9-22-17-18(23-15)27(25-24-17)11-12-1-4-16-20-5-6-26(16)10-12/h1-6,8-10H,11H2 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
Hutchison MediPharma Limited
Curated by ChEMBL
| Assay Description
Inhibition of c-Met autophosphorylation in human NCI-H441 cells for 1 hr by ELISA |
J Med Chem 57: 7577-89 (2014)
Article DOI: 10.1021/jm500510f
BindingDB Entry DOI: 10.7270/Q2JD4ZCR |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50023306
(CHEMBL3334549)Show SMILES OCCn1cc(cn1)-c1cnc2nnn(Cc3n[nH]c4ncccc34)c2n1 Show InChI InChI=1S/C16H14N10O/c27-5-4-25-8-10(6-19-25)12-7-18-15-16(20-12)26(24-23-15)9-13-11-2-1-3-17-14(11)22-21-13/h1-3,6-8,27H,4-5,9H2,(H,17,21,22) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
Hutchison MediPharma Limited
Curated by ChEMBL
| Assay Description
Inhibition of c-Met autophosphorylation in human NCI-H441 cells for 1 hr by ELISA |
J Med Chem 57: 7577-89 (2014)
Article DOI: 10.1021/jm500510f
BindingDB Entry DOI: 10.7270/Q2JD4ZCR |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50023345
(CHEMBL3334570)Show SMILES C[C@H](c1ccn2nccc2c1)n1nnc2ncc(nc12)-c1cnn(CCO)c1 |r| Show InChI InChI=1S/C18H17N9O/c1-12(13-3-5-26-15(8-13)2-4-20-26)27-18-17(23-24-27)19-10-16(22-18)14-9-21-25(11-14)6-7-28/h2-5,8-12,28H,6-7H2,1H3/t12-/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 27 | n/a | n/a | n/a | n/a | n/a | n/a |
Hutchison MediPharma Limited
Curated by ChEMBL
| Assay Description
Inhibition of c-Met autophosphorylation in human NCI-H441 cells for 1 hr by ELISA |
J Med Chem 57: 7577-89 (2014)
Article DOI: 10.1021/jm500510f
BindingDB Entry DOI: 10.7270/Q2JD4ZCR |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50023345
(CHEMBL3334570)Show SMILES C[C@H](c1ccn2nccc2c1)n1nnc2ncc(nc12)-c1cnn(CCO)c1 |r| Show InChI InChI=1S/C18H17N9O/c1-12(13-3-5-26-15(8-13)2-4-20-26)27-18-17(23-24-27)19-10-16(22-18)14-9-21-25(11-14)6-7-28/h2-5,8-12,28H,6-7H2,1H3/t12-/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
Hutchison MediPharma Limited
Curated by ChEMBL
| Assay Description
Inhibition of c-Met (unknown origin) using Poly E4Y substrate and ATP incubated for 45 mins by fluorescence polarization assay |
J Med Chem 57: 7577-89 (2014)
Article DOI: 10.1021/jm500510f
BindingDB Entry DOI: 10.7270/Q2JD4ZCR |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50023337
(CHEMBL3334562)Show SMILES N#Cc1ccc(cn1)-c1cnc2nnn(Cc3n[nH]c4ncccc34)c2n1 Show InChI InChI=1S/C17H10N10/c18-6-11-4-3-10(7-20-11)13-8-21-16-17(22-13)27(26-25-16)9-14-12-2-1-5-19-15(12)24-23-14/h1-5,7-8H,9H2,(H,19,23,24) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 31 | n/a | n/a | n/a | n/a | n/a | n/a |
Hutchison MediPharma Limited
Curated by ChEMBL
| Assay Description
Inhibition of c-Met autophosphorylation in human NCI-H441 cells for 1 hr by ELISA |
J Med Chem 57: 7577-89 (2014)
Article DOI: 10.1021/jm500510f
BindingDB Entry DOI: 10.7270/Q2JD4ZCR |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50023343
(CHEMBL3334568)Show SMILES C[C@H](c1ccc2nccn2c1)n1nnc2ncc(nc12)-c1cnn(C)c1 |r| Show InChI InChI=1S/C17H15N9/c1-11(12-3-4-15-18-5-6-25(15)10-12)26-17-16(22-23-26)19-8-14(21-17)13-7-20-24(2)9-13/h3-11H,1-2H3/t11-/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 32 | n/a | n/a | n/a | n/a | n/a | n/a |
Hutchison MediPharma Limited
Curated by ChEMBL
| Assay Description
Inhibition of c-Met autophosphorylation in human NCI-H441 cells for 1 hr by ELISA |
J Med Chem 57: 7577-89 (2014)
Article DOI: 10.1021/jm500510f
BindingDB Entry DOI: 10.7270/Q2JD4ZCR |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50023343
(CHEMBL3334568)Show SMILES C[C@H](c1ccc2nccn2c1)n1nnc2ncc(nc12)-c1cnn(C)c1 |r| Show InChI InChI=1S/C17H15N9/c1-11(12-3-4-15-18-5-6-25(15)10-12)26-17-16(22-23-26)19-8-14(21-17)13-7-20-24(2)9-13/h3-11H,1-2H3/t11-/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 32 | n/a | n/a | n/a | n/a | n/a | n/a |
Hutchison MediPharma Limited
Curated by ChEMBL
| Assay Description
Inhibition of c-Met (unknown origin) using Poly E4Y substrate and ATP incubated for 45 mins by fluorescence polarization assay |
J Med Chem 57: 7577-89 (2014)
Article DOI: 10.1021/jm500510f
BindingDB Entry DOI: 10.7270/Q2JD4ZCR |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50023332
(CHEMBL3334550)Show InChI InChI=1S/C17H15N9O/c27-6-5-25-11-13(7-20-25)14-8-19-16-17(21-14)26(23-22-16)10-12-1-2-15-18-3-4-24(15)9-12/h1-4,7-9,11,27H,5-6,10H2 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 33 | n/a | n/a | n/a | n/a | n/a | n/a |
Hutchison MediPharma Limited
Curated by ChEMBL
| Assay Description
Inhibition of c-Met autophosphorylation in human NCI-H441 cells for 1 hr by ELISA |
J Med Chem 57: 7577-89 (2014)
Article DOI: 10.1021/jm500510f
BindingDB Entry DOI: 10.7270/Q2JD4ZCR |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50023287
(CHEMBL3334560)Show InChI InChI=1S/C16H12N8S/c1-23-8-11(6-19-23)13-7-18-15-16(20-13)24(22-21-15)9-12-4-10-5-17-3-2-14(10)25-12/h2-8H,9H2,1H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 61 | n/a | n/a | n/a | n/a | n/a | n/a |
Hutchison MediPharma Limited
Curated by ChEMBL
| Assay Description
Inhibition of c-Met autophosphorylation in human NCI-H441 cells for 1 hr by ELISA |
J Med Chem 57: 7577-89 (2014)
Article DOI: 10.1021/jm500510f
BindingDB Entry DOI: 10.7270/Q2JD4ZCR |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50023292
(CHEMBL3334545)Show InChI InChI=1S/C15H12N10/c1-23-8-10(6-18-23)12-7-17-14-15(19-12)25(22-20-14)9-11-2-3-13-16-4-5-24(13)21-11/h2-8H,9H2,1H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 63 | n/a | n/a | n/a | n/a | n/a | n/a |
Hutchison MediPharma Limited
Curated by ChEMBL
| Assay Description
Inhibition of c-Met autophosphorylation in human NCI-H441 cells for 1 hr by ELISA |
J Med Chem 57: 7577-89 (2014)
Article DOI: 10.1021/jm500510f
BindingDB Entry DOI: 10.7270/Q2JD4ZCR |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50440890
(CHEMBL2431841 | US9066954, 341)Show InChI InChI=1S/C19H15N7/c1-25-12-15(11-21-25)17-6-7-18-22-23-19(26(18)24-17)10-13-4-5-16-14(9-13)3-2-8-20-16/h2-9,11-12H,10H2,1H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 69 | n/a | n/a | n/a | n/a | n/a | n/a |
Hutchison MediPharma Limited
Curated by ChEMBL
| Assay Description
Inhibition of c-Met autophosphorylation in human NCI-H441 cells for 1 hr by ELISA |
J Med Chem 57: 7577-89 (2014)
Article DOI: 10.1021/jm500510f
BindingDB Entry DOI: 10.7270/Q2JD4ZCR |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50023291
(CHEMBL3334544)Show InChI InChI=1S/C15H12N10/c1-23-8-11(4-18-23)12-5-16-14-15(20-12)25(22-21-14)7-10-2-3-13-17-9-19-24(13)6-10/h2-6,8-9H,7H2,1H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 77 | n/a | n/a | n/a | n/a | n/a | n/a |
Hutchison MediPharma Limited
Curated by ChEMBL
| Assay Description
Inhibition of c-Met autophosphorylation in human NCI-H441 cells for 1 hr by ELISA |
J Med Chem 57: 7577-89 (2014)
Article DOI: 10.1021/jm500510f
BindingDB Entry DOI: 10.7270/Q2JD4ZCR |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50023280
(CHEMBL3334553)Show InChI InChI=1S/C19H15N7/c1-25-11-15(8-23-25)17-9-21-18-19(24-17)26(12-22-18)10-13-4-5-16-14(7-13)3-2-6-20-16/h2-9,11-12H,10H2,1H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 96 | n/a | n/a | n/a | n/a | n/a | n/a |
Hutchison MediPharma Limited
Curated by ChEMBL
| Assay Description
Inhibition of c-Met (unknown origin) using Poly E4Y substrate and ATP incubated for 45 mins by fluorescence polarization assay |
J Med Chem 57: 7577-89 (2014)
Article DOI: 10.1021/jm500510f
BindingDB Entry DOI: 10.7270/Q2JD4ZCR |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50023280
(CHEMBL3334553)Show InChI InChI=1S/C19H15N7/c1-25-11-15(8-23-25)17-9-21-18-19(24-17)26(12-22-18)10-13-4-5-16-14(7-13)3-2-6-20-16/h2-9,11-12H,10H2,1H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
Hutchison MediPharma Limited
Curated by ChEMBL
| Assay Description
Inhibition of c-Met autophosphorylation in human NCI-H441 cells for 1 hr by ELISA |
J Med Chem 57: 7577-89 (2014)
Article DOI: 10.1021/jm500510f
BindingDB Entry DOI: 10.7270/Q2JD4ZCR |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50023290
(CHEMBL3334543)Show InChI InChI=1S/C15H12N10/c1-23-7-10(4-19-23)12-5-18-14-15(20-12)25(22-21-14)9-11-8-24-3-2-16-13(24)6-17-11/h2-8H,9H2,1H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
Hutchison MediPharma Limited
Curated by ChEMBL
| Assay Description
Inhibition of c-Met (unknown origin) using Poly E4Y substrate and ATP incubated for 45 mins by fluorescence polarization assay |
J Med Chem 57: 7577-89 (2014)
Article DOI: 10.1021/jm500510f
BindingDB Entry DOI: 10.7270/Q2JD4ZCR |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50023294
(CHEMBL3334547)Show InChI InChI=1S/C15H12N10/c1-23-8-10(6-18-23)12-7-16-14-15(20-12)25(22-21-14)9-11-3-5-24-13(19-11)2-4-17-24/h2-8H,9H2,1H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 142 | n/a | n/a | n/a | n/a | n/a | n/a |
Hutchison MediPharma Limited
Curated by ChEMBL
| Assay Description
Inhibition of c-Met (unknown origin) using Poly E4Y substrate and ATP incubated for 45 mins by fluorescence polarization assay |
J Med Chem 57: 7577-89 (2014)
Article DOI: 10.1021/jm500510f
BindingDB Entry DOI: 10.7270/Q2JD4ZCR |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50023286
(CHEMBL3334559)Show InChI InChI=1S/C16H12N8S/c1-23-8-11(6-19-23)13-7-18-14-15(20-13)24(22-21-14)9-12-5-10-3-2-4-17-16(10)25-12/h2-8H,9H2,1H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 194 | n/a | n/a | n/a | n/a | n/a | n/a |
Hutchison MediPharma Limited
Curated by ChEMBL
| Assay Description
Inhibition of c-Met (unknown origin) using Poly E4Y substrate and ATP incubated for 45 mins by fluorescence polarization assay |
J Med Chem 57: 7577-89 (2014)
Article DOI: 10.1021/jm500510f
BindingDB Entry DOI: 10.7270/Q2JD4ZCR |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50440890
(CHEMBL2431841 | US9066954, 341)Show InChI InChI=1S/C19H15N7/c1-25-12-15(11-21-25)17-6-7-18-22-23-19(26(18)24-17)10-13-4-5-16-14(9-13)3-2-8-20-16/h2-9,11-12H,10H2,1H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 210 | n/a | n/a | n/a | n/a | n/a | n/a |
Hutchison MediPharma Limited
Curated by ChEMBL
| Assay Description
Inhibition of c-Met (unknown origin) using Poly E4Y substrate and ATP incubated for 45 mins by fluorescence polarization assay |
J Med Chem 57: 7577-89 (2014)
Article DOI: 10.1021/jm500510f
BindingDB Entry DOI: 10.7270/Q2JD4ZCR |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50023282
(CHEMBL3334555)Show SMILES OCCn1cc(cn1)-c1cnc2nnn(Cc3cc4cccnc4[nH]3)c2n1 Show InChI InChI=1S/C17H15N9O/c27-5-4-25-9-12(7-20-25)14-8-19-16-17(22-14)26(24-23-16)10-13-6-11-2-1-3-18-15(11)21-13/h1-3,6-9,27H,4-5,10H2,(H,18,21) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 227 | n/a | n/a | n/a | n/a | n/a | n/a |
Hutchison MediPharma Limited
Curated by ChEMBL
| Assay Description
Inhibition of c-Met (unknown origin) using Poly E4Y substrate and ATP incubated for 45 mins by fluorescence polarization assay |
J Med Chem 57: 7577-89 (2014)
Article DOI: 10.1021/jm500510f
BindingDB Entry DOI: 10.7270/Q2JD4ZCR |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50023297
(CHEMBL3334548)Show InChI InChI=1S/C15H12N10/c1-23-8-11(5-18-23)12-6-16-14-15(20-12)25(22-21-14)7-10-2-3-24-13(4-10)17-9-19-24/h2-6,8-9H,7H2,1H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 359 | n/a | n/a | n/a | n/a | n/a | n/a |
Hutchison MediPharma Limited
Curated by ChEMBL
| Assay Description
Inhibition of c-Met (unknown origin) using Poly E4Y substrate and ATP incubated for 45 mins by fluorescence polarization assay |
J Med Chem 57: 7577-89 (2014)
Article DOI: 10.1021/jm500510f
BindingDB Entry DOI: 10.7270/Q2JD4ZCR |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50023285
(CHEMBL3334558)Show InChI InChI=1S/C16H12N8S/c1-23-7-10(5-19-23)13-6-18-14-15(20-13)24(22-21-14)8-11-9-25-16-12(11)3-2-4-17-16/h2-7,9H,8H2,1H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 378 | n/a | n/a | n/a | n/a | n/a | n/a |
Hutchison MediPharma Limited
Curated by ChEMBL
| Assay Description
Inhibition of c-Met (unknown origin) using Poly E4Y substrate and ATP incubated for 45 mins by fluorescence polarization assay |
J Med Chem 57: 7577-89 (2014)
Article DOI: 10.1021/jm500510f
BindingDB Entry DOI: 10.7270/Q2JD4ZCR |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50023341
(CHEMBL3334566)Show InChI InChI=1S/C16H16N8O/c1-2-13-17-3-4-23(13)10-12(1)11-24-16-15(20-21-24)18-9-14(19-16)22-5-7-25-8-6-22/h1-4,9-10H,5-8,11H2 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 787 | n/a | n/a | n/a | n/a | n/a | n/a |
Hutchison MediPharma Limited
Curated by ChEMBL
| Assay Description
Inhibition of c-Met (unknown origin) using Poly E4Y substrate and ATP incubated for 45 mins by fluorescence polarization assay |
J Med Chem 57: 7577-89 (2014)
Article DOI: 10.1021/jm500510f
BindingDB Entry DOI: 10.7270/Q2JD4ZCR |
More data for this
Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50023281
(CHEMBL3334554)Show InChI InChI=1S/C19H15N7/c1-25-12-16(10-22-25)15-8-18-19(21-9-15)23-24-26(18)11-13-4-5-17-14(7-13)3-2-6-20-17/h2-10,12H,11H2,1H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Hutchison MediPharma Limited
Curated by ChEMBL
| Assay Description
Inhibition of c-Met (unknown origin) using Poly E4Y substrate and ATP incubated for 45 mins by fluorescence polarization assay |
J Med Chem 57: 7577-89 (2014)
Article DOI: 10.1021/jm500510f
BindingDB Entry DOI: 10.7270/Q2JD4ZCR |
More data for this
Ligand-Target Pair | |
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